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Evidence-based Complementary and Alternative Medicine : eCAM logoLink to Evidence-based Complementary and Alternative Medicine : eCAM
. 2026 Apr 7;2026:9832583. doi: 10.1155/ecam/9832583

RETRACTION: Antiproliferative Effect of Rottlerin on Sk‐Mel‐28 Melanoma Cells

Evidence-Based Complementary and Alternative Medicine
PMCID: PMC13063789  PMID: 41971410

RETRACTION: E. Daveri, G. Valacchi, R. Romagnoli, E. Maellaro, and E. Maioli, “Antiproliferative Effect of Rottlerin on Sk‐Mel‐28 Melanoma Cells,” Evidence-Based Complementary and Alternative Medicine, 2015, 545838, https://doi.org/10.1155/2015/545838.

The above article, published online on 28 May 2015 in Wiley Online Library (https://wileyonlinelibrary.com), has been retracted by John Wiley & Sons Ltd. The retraction has been agreed due to concerns raised with the figures. Specifically:

  • After resizing, the ß‐actin bands in Figure 2 appear highly similar to lanes 2–5 of the first set of ß‐actin bands shown in Figure 2 of [1].

  • In Figure 4, there are areas of the Western blot background that appear identical between lanes 2 and 4 of Cyclin D1 and lanes 1 and 3 of p21/Cip1

  • Multiple other blots in the article show evidence of undeclared splicing

The authors provided a response to the concerns but were unable to provide the original western blots. After assessment, the results and conclusions presented can no longer be considered reliable, and the article is retracted.

The authors disagree with the retraction.

References

  • 1. Torricelli C., Salvadori S., Valacchi G. et al., Alternative Pathways of Cancer Cell Death by Rottlerin: Apoptosis Versus Autophagy, Evidence-Based Complementary and Alternative Medicine. (2012) 10.1155/2012/980658, 2-s2.0-84872168410. [DOI] [PMC free article] [PubMed] [Google Scholar]

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