Goto T, Saligan LN, Juneau P, Gonsalves SG, Rio CJ, Graves LY, Von Ah D. Characterization of Cancer Survivors Clustered by Subjective and Objective Cognitive Function Scores. Cancer Medicine. 2024;(12):e7255. doi: https://doi.org/10.1002/cam4.7255.
Following publication of the article [1], we became aware that the SF‐36 Bodily Pain measure had been described and interpreted with an incorrect score direction. Specifically, the 2‐item Bodily Pain subscale of the 36‐Item Short‐Form Health Survey (SF‐36) is scored on a 0–100 transformed scale in which higher values represent less bodily pain (better health status) and lower values represent more bodily pain (worse health status) [2]. In the published version, we mistakenly stated/implied that higher Bodily Pain scores reflected greater pain severity, which is opposite to the SF‐36 scoring convention.
This issue is limited to the narrative description and interpretation of the Bodily Pain scale and does not change any statistical results (including p‐values), because all analyses were performed using appropriately scored SF‐36 Bodily Pain values. We have revised the relevant statements in the Methods, Results, Discussion, and Supporting Information to ensure that the interpretation of SF‐36 Bodily Pain scores is accurate and consistent throughout.
Methods
Psychoneurological (PN) Symptoms
Bodily pain was measured using the SF‐36 [2]. For this subscale, higher scores indicate less bodily pain (i.e., better health status), whereas lower scores indicate more bodily pain.
In contrast, higher scores on the respective questionnaires indicate more pronounced symptomatology for anxiety, depression, fatigue, neuropathic pain, and sleep disturbance. The directions and ranges of scores are available in Table S3.
Results
Symptom Phenotypes of Each Cluster
Bodily pain was greatest (lowest SF‐36 Bodily Pain scores) in Cluster 1 and least (highest scores) in Cluster 5 (Kruskal–Wallis test, p < 0.0001) (Figure 5B).
Discussion
Cluster 5 had graduate educational degrees, the highest physical function, dispositional optimism, overall social support, and the mildest symptomatology. On the contrary, participants in Cluster 1 were mostly unemployed or homemakers, mostly earning < $15 K, with the lowest educational attainment and physical function, but the greatest bodily pain, fatigue, and neuropathic pain.
Supplementary Materials
Table S3. Symptom phenotypes in each cluster group.
| Direction higher is | Range of scores | Central tendency (N = 414) | Cluster | p‐value | Test | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 (n = 59) | 2 (n = 59) | 3 (n = 102) | 4 (n = 92) | 5 (n = 102) | |||||||
| PROMIS | Anxiety [square root] | Worse | 8–40 [2.8–6.3] | 4.3 (0.8) | 4.9 (0.6) | 5.2 (0.5) | 4.4 (0.5) | 3.6 (0.5) | 3.9 (0.7) | <0.001 | a |
| Depression | Worse | 8–40 | 15 (11.8) | 22 (9) | 28 (6.5) | 16.5 (7) | 11 (6) | 10 (4) | <0.001 | k | |
| Fatigue | Worse | 8–40 | 24.2 (8.5) | 33.6 (5.7) | 30.0 (6.3) | 26.5 (5.8) | 21.3 (6.7) | 15.7 (5.0) | <0.001 | a | |
| Neuropathic Pain | Worse | 5–25 | 8 (7) | 19 (6) | 9 (3.5) | 7 (5) | 9 (7) | 5 (2) | <0.001 | k | |
| Sleep Disturbance | Worse | 8–40 | 23.9 (8.2) | 30.1 (7.4) | 30.0 (6.2) | 27.3 (6.4) | 18.0 (5.6) | 18.7 (6.1) | <0.001 | a | |
| SF‐36 | Bodily Pain | Better | 0–100 | 57.5 (45) | 32.5 (11.2) | 45 (35) | 67.5 (32.5) | 45 (25) | 90 (12.5) | <0.001 | k |
a, analysis of variance, the values are shown as mean (standard deviation); k, Kruskal‐Wallis test, the values are shown as median (interquartile range); PROMIS, Patient‐Reported Outcomes Measurement Information System; SF‐36, 36‐Item Short‐Form Health Survey.
We apologize for this error.
References
- 1. Goto T., Saligan L. N., Juneau P., et al., “Characterization of cancer survivors clustered by subjective and objective cognitive function scores,” Cancer Medicine 13, no. 12 (2024): e7255, 10.1002/cam4.7255. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2. Hays R. D., Sherbourne C. D., and Mazel R. M., “The RAND 36‐Item Health Survey 1.0,” Health Economics 2, no. 3 (1993): 217–227, 10.1002/hec.4730020305. [DOI] [PubMed] [Google Scholar]
