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. 2026 Apr 16;18(4):r225. doi: 10.7759/cureus.r225

Retraction: Evaluating the Anticancer Activity of Blocking TNF Type 1 Receptors in Thioacetamide-Induced Hepatocellular Carcinoma in a Rat Model

Alaa Bagalagel 1,2, Reem Diri 2, Ahmed Noor 2, Deina Almasri 2, Hussain Bakhsh 3, Hussam I Kutbi 2, Mohammed M Al-Gayyar 4,5,
Editors: Alexander Muacevic, John R Adler
PMCID: PMC13086177  PMID: 42006517

The Editor-in-Chief is retracting this article because it contains multiple internal inconsistencies between the reported results, their interpretation, and the stated conclusions, particularly regarding expression of Nrf2 and HO-1. Their expression is described in conflicting directions across different sections, and the findings are not coherently aligned with the proposed mechanisms. These discrepancies raise concerns about the accuracy of data interpretation and the reliability of the study’s conclusions, thereby undermining its overall scientific validity. The authors disagree with the decision to retract.

No competing interests declared.


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