. 2026 Jan 10;399(6):8693–8707. doi: 10.1007/s00210-025-04920-3

Table 2.

The effect of LF (10 mg/kg/48 h, p.o.) and PZQ (300 mg/kg/day, p.o) co-treatment for 8 weeks on serum creatinine, blood urea nitrogen, and albumin

Groups	Serum creatinine (mg/dl)	BUN (mg/dl)	Albumin (g/dl)
Control	0.16 ± 0.01	32.52 ± 1.18	3.8 ± 0.23
LF	0.88 ± 0.01^a	69.15 ± 3.73^a	2.77 ± 0.14^a
LF + PZQ	0.25 ± 0.02^ab	45.48 ± 1.49^ab	3.31 ± 0.18^ab
PZQ	0.15 ± 0.01^b	34.2 ± 2.17^b	3.68 ± 0.22^b

Mean ± S.D. (n = 6) is how the data are presented. a, b: Statistically distinct from the control and LF groups, respectively, at P < 0.05, as determined by ANOVA with subsequent Tukey–Kramer post-hoc analysis

LF Leflunomide, PZQ Praziquantel, BUN Blood Urea Nitrogen