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. 1975 Apr;246(3):673–694. doi: 10.1113/jphysiol.1975.sp010910

Effects of post-operative visual environments on reorganization of retinotectal projection in goldfish.

M G Yoon
PMCID: PMC1309441  PMID: 1133792

Abstract

1. Possible influence of different visual environments on the reorganization of retinotectal projection was studied with neurophysiological mapping methods following excision of the caudal half of the optic tectum in adult goldfish. 2. Post-operative light-deprivation showed no significant effects: in the absence of visual input, the visual projection from the whole retina because compressed on to the remaining rostral half-tectum in correct retinotopic order within 4 months, regardless of whether the contralateral optic nerve was left intact, or severed and then allowed to regenerate. 3. When the operated goldfish were continually exposed to visual stimuli without any dark period (post-operative dark-deprivation), two different results were observed: if the optic nerve was sectioned, in addition to excision of the caudal tectum, an orderly field compression was observed within 70 days in the re-established retinotectal projection; on the other hand, if the optic nerve was left intact, the dark-deprived fish retained the original connexions between the remaining rostral half-tectum and the temporal hemiretina without showing any sign of field compression for up to 253 days. 4. When the dark-deprived fish was then transferred into darkness, the suppressive effect disappeared: a compression of the retinotectal projection was induced within 2 or 3 weeks after the transfer. 5. Histological preparations of the fish brains showed consistent morphologic changes in the laminar structure of the remaining half-tectum. The stratum opticum and the stratum fibrosum et griseum superficiale merged together to form a new layer which contained an intricate network of thick fibre bundles.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ATTARDI D. G., SPERRY R. W. Preferential selection of central pathways by regenerating optic fibers. Exp Neurol. 1963 Jan;7:46–64. doi: 10.1016/0014-4886(63)90093-1. [DOI] [PubMed] [Google Scholar]
  2. GAZE R. M. The representation of the retina on the optic lobe of the frog. Q J Exp Physiol Cogn Med Sci. 1958 Apr;43(2):209–214. doi: 10.1113/expphysiol.1958.sp001318. [DOI] [PubMed] [Google Scholar]
  3. Gaze R. M., Sharma S. C. Axial differences in the reinnervation of the goldfish optic tectum by regenerating optic nerve fibres. Exp Brain Res. 1970;10(2):171–181. [PubMed] [Google Scholar]
  4. HAMDI F. A., WHITTERIDGE D. The representation of the retina on the optic tectum of the pigeon. Q J Exp Physiol Cogn Med Sci. 1954;39(2):111–119. doi: 10.1113/expphysiol.1954.sp001053. [DOI] [PubMed] [Google Scholar]
  5. Hunt R. K., Jacobson M. Neuronal specificity revisited. Curr Top Dev Biol. 1974;8:203–259. [PubMed] [Google Scholar]
  6. JACOBSON M., GAZE R. M. TYPES OF VISUAL RESPONSE FROM SINGLE UNITS IN THE OPTIC TECTUM AND OPTIC NERVE OF THE GOLDFISH. Q J Exp Physiol Cogn Med Sci. 1964 Apr;49:199–209. doi: 10.1113/expphysiol.1964.sp001720. [DOI] [PubMed] [Google Scholar]
  7. Jacobson M., Gaze R. M. Selection of appropriate tectal connections by regenerating optic nerve fibers in adult goldfish. Exp Neurol. 1965 Dec;13(4):418–430. doi: 10.1016/0014-4886(65)90128-7. [DOI] [PubMed] [Google Scholar]
  8. LEGHISSA S. La struttura microscopica e la citoarchitettonica del tetto ottico dei pesci teleostei. Z Anat Entwicklungsgesch. 1955;118(5):427–463. [PubMed] [Google Scholar]
  9. Laufer M., Vanegas H. The optic tectum of a perciform teleost. 3. Electron microscopy of degenerating retino-tectal afferents. J Comp Neurol. 1974 Mar 1;154(1):97–115. doi: 10.1002/cne.901540106. [DOI] [PubMed] [Google Scholar]
  10. Laufer M., Vanegas H. The optic tectum of a perciform teleost. II. Fine structure. J Comp Neurol. 1974 Mar 1;154(1):61–95. doi: 10.1002/cne.901540105. [DOI] [PubMed] [Google Scholar]
  11. SCHWASSMAN H. O., KRUGER L. ORGANIZATION OF THE VISUAL PROJECTION UPON THE OPTIC TECTUM OF SOME FRESHWATER FISH. J Comp Neurol. 1965 Feb;124:113–126. doi: 10.1002/cne.901240109. [DOI] [PubMed] [Google Scholar]
  12. SPERRY R. W. CHEMOAFFINITY IN THE ORDERLY GROWTH OF NERVE FIBER PATTERNS AND CONNECTIONS. Proc Natl Acad Sci U S A. 1963 Oct;50:703–710. doi: 10.1073/pnas.50.4.703. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Sharma S. C. Anomalous retinal projection after removal of contralateral optic tectum in adult goldfish. Exp Neurol. 1973 Dec;41(3):661–669. doi: 10.1016/0014-4886(73)90058-7. [DOI] [PubMed] [Google Scholar]
  14. Sharma S. C. Redistribution of visual projections in altered optic tecta of adult goldfish. Proc Natl Acad Sci U S A. 1972 Sep;69(9):2637–2639. doi: 10.1073/pnas.69.9.2637. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Sharma S. C. Reformation of retinotectal projections after various tectal ablations in adult goldfish. Exp Neurol. 1972 Jan;34(1):171–182. doi: 10.1016/0014-4886(72)90197-5. [DOI] [PubMed] [Google Scholar]
  16. Sharma S. C. The retinal projections in the goldfish: an experimental study. Brain Res. 1972 Apr 14;39(1):213–223. doi: 10.1016/0006-8993(72)90796-2. [DOI] [PubMed] [Google Scholar]
  17. Vanegas H., Ebbesson S. O. Retinal projections in the perch-like teleost Eugerres plumieri. J Comp Neurol. 1973 Oct 15;151(4):331–357. doi: 10.1002/cne.901510404. [DOI] [PubMed] [Google Scholar]
  18. Vanegas H., Laufer M., Amat J. The optic tectum of a perciform teleost. I. General configuration and cytoarchitecture. J Comp Neurol. 1974 Mar 1;154(1):43–60. doi: 10.1002/cne.901540104. [DOI] [PubMed] [Google Scholar]
  19. Yoon M. G. Retention of the original topographic polarity by the 180 degrees rotated tectal reimplant in young adult goldfish. J Physiol. 1973 Sep;233(3):575–588. doi: 10.1113/jphysiol.1973.sp010324. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Yoon M. G. Transposition of the visual projection from the nasal hemiretina onto the foreign rostral zone of the optic tectum in goldfish. Exp Neurol. 1972 Dec;37(3):451–462. doi: 10.1016/0014-4886(72)90088-x. [DOI] [PubMed] [Google Scholar]
  21. Yoon M. Reorganization of retinotectal projection following surgical operations on the optic tectum in goldfish. Exp Neurol. 1971 Nov;33(2):395–411. doi: 10.1016/0014-4886(71)90031-8. [DOI] [PubMed] [Google Scholar]
  22. Yoon M. Reversibility of the reorganization of retinotectal projection in goldfish. Exp Neurol. 1972 Jun;35(3):565–577. doi: 10.1016/0014-4886(72)90128-8. [DOI] [PubMed] [Google Scholar]

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