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. 1967;65:661–704.

Cataracts and galactose metabolism.

W A Wilson
PMCID: PMC1310285  PMID: 6083070

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ANDERSON E. P., KALCKAR H. M., KURAHASHI K., ISSELBACHER K. J. A specific enzymatic assay for the diagnosis of congenital galactosemia. I. The consumption test. J Lab Clin Med. 1957 Sep;50(3):469–477. [PubMed] [Google Scholar]
  2. CAPUTTO R., LELOIR L. F., CARDINI C. E., PALADINI A. C. Isolation of the coenzyme of the galactose phosphate-glucose phosphate transformation. J Biol Chem. 1950 May;184(1):333–350. [PubMed] [Google Scholar]
  3. COTLIER E. Hypophysectomy effect on lens epithelium mitosis and galactose cataract development in rats. Arch Ophthalmol. 1962 Apr;67:476–482. doi: 10.1001/archopht.1962.00960020476016. [DOI] [PubMed] [Google Scholar]
  4. Cotlier E., Becker B. Topical corticosteroids and galactose cataracts. Invest Ophthalmol. 1965 Oct;4(5):806–814. [PubMed] [Google Scholar]
  5. DISCHE Z., BORENFREUND E., ZELMENIS G. Proteins and protein synthesis in rat lenses with galactose cataract. AMA Arch Ophthalmol. 1956 May;55(5):633–642. doi: 10.1001/archopht.1956.00930030637003. [DOI] [PubMed] [Google Scholar]
  6. DONNELL G. N., BERGREN W. R., BRETTHAUER R. K., HANSEN R. G. The enzymatic expression of heterozygosity in families of children with galactosemia. Pediatrics. 1960 Apr;25:572–581. [PubMed] [Google Scholar]
  7. DONNELL G. N., BERGREN W. R., ROLDAN M. Genetic studies in galactosemia. I. The oral galactose tolerance test and the heterozygous state. Pediatrics. 1959 Sep;24:418–426. [PubMed] [Google Scholar]
  8. DONNELL G. N., LANN S. H. Galactosemia. Report of four cases. Pediatrics. 1951 Apr;7(4):503–515. [PubMed] [Google Scholar]
  9. FENTON J. C. THE ESTIMATION OF GALACTOSE-I-PHOSPHATE IN RED CELLS. Clin Chim Acta. 1965 Mar;11:205–211. doi: 10.1016/0009-8981(65)90064-1. [DOI] [PubMed] [Google Scholar]
  10. FRIEDENWALD J. S., RYTEL D. Contribution to the histopathology of cataract. AMA Arch Ophthalmol. 1955 Jun;53(6):825–831. doi: 10.1001/archopht.1955.00930010833007. [DOI] [PubMed] [Google Scholar]
  11. GILLOT F., SCHAEFER J. C., DALAUT J. C. Premiere observation algérienne de galactosémie congénitale. Arch Fr Pediatr. 1957;14(7):724–732. [PubMed] [Google Scholar]
  12. HANSEN R. G., BRETTHAUER R. K., MAYES J., NORDIN J. H. ESTIMATION OF FREQUENCY OF OCCURRENCE OF GALACTOSEMIA IN THE POPULATION. Proc Soc Exp Biol Med. 1964 Feb;115:560–563. doi: 10.3181/00379727-115-28968. [DOI] [PubMed] [Google Scholar]
  13. HOLZEL A., KOMROWER G. M. A study of the genetics of galactosaemia. Arch Dis Child. 1955 Apr;30(150):155–159. doi: 10.1136/adc.30.150.155. [DOI] [PMC free article] [PubMed] [Google Scholar]
  14. HSIA D. Y., HUANG I., DRISCOLL S. G. The heterozygous carrier in galactosaemia. Nature. 1958 Nov 15;182(4646):1389–1390. doi: 10.1038/1821389a0. [DOI] [PubMed] [Google Scholar]
  15. HSIA D. Y., WALKER F. A. Variability in the clinical manifestations of galactosemia. J Pediatr. 1961 Dec;59:872–883. doi: 10.1016/s0022-3476(61)80317-x. [DOI] [PubMed] [Google Scholar]
  16. ISSELBACHER K. J. Evidence for accessory pathway of galactose metabolism in mammalian liver. Science. 1957 Oct 4;126(3275):652–654. doi: 10.1126/science.126.3275.652-a. [DOI] [PubMed] [Google Scholar]
  17. JOHNSON J. Cataracts in galactosemia. Am J Ophthalmol. 1953 Oct;36(10):1380–1386. doi: 10.1016/0002-9394(53)90796-x. [DOI] [PubMed] [Google Scholar]
  18. KALCKAR H. M., ANDERSON E. P., ISSELBACHER K. J. Galactosemia, a congenital defect in a nucleotide transferase. Biochim Biophys Acta. 1956 Apr;20(1):262–268. doi: 10.1016/0006-3002(56)90285-2. [DOI] [PubMed] [Google Scholar]
  19. KINOSHITA J. H., MEROLA L. O., DIKMAK E. The accumulation of dulcitol and water in rabbit lens incubated with galactose. Biochim Biophys Acta. 1962 Jul 30;62:176–178. doi: 10.1016/0006-3002(62)90508-5. [DOI] [PubMed] [Google Scholar]
  20. KINOSHITA J. H., MEROLA L. O., DIKMAK E. The accumulation of dulcitol and water in rabbit lens incubated with galactose. Biochim Biophys Acta. 1962 Jul 30;62:176–178. doi: 10.1016/0006-3002(62)90508-5. [DOI] [PubMed] [Google Scholar]
  21. KINOSHITA J. H., MEROLA L. O. HYDRATION OF THE LENS DURING THE DEVELOPMENT OF GALACTOSE CATARACT. Invest Ophthalmol. 1964 Dec;3:577–584. [PubMed] [Google Scholar]
  22. KIRKMAN H. N., BYNUM E. Enzymic evidence of a galactosemic trait in parents of galactosemic children. Ann Hum Genet. 1959 Apr;23(2):117–126. doi: 10.1111/j.1469-1809.1958.tb01456.x. [DOI] [PubMed] [Google Scholar]
  23. KIRKMAN H. N., MAXWELL E. S. Enzymatic estimation of erythrocytic galactose-1-phosphate. J Lab Clin Med. 1960 Jul;56:161–166. [PubMed] [Google Scholar]
  24. Kalckar H. M., Anderson E. P., Isselbacher K. J. GALACTOSEMIA, A CONGENITAL DEFECT IN A NUCLEOTIDE TRANSFERASE: A PRELIMINARY REPORT. Proc Natl Acad Sci U S A. 1956 Feb;42(2):49–51. doi: 10.1073/pnas.42.2.49. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. Kinoshita J. H. Cataracts in galactosemia. The Jonas S. Friedenwald Memorial Lecture. Invest Ophthalmol. 1965 Oct;4(5):786–799. [PubMed] [Google Scholar]
  26. LELOIR L. F. The enzymatic transformation of uridine diphosphate glucose into a galactose derivative. Arch Biochem Biophys. 1951 Sep;33(2):186–190. doi: 10.1016/0003-9861(51)90096-3. [DOI] [PubMed] [Google Scholar]
  27. LERMAN S., DEVI A., HAWES S. The incorporation of labelled amino acids into lens protein of normal, galactose, and xylose-fed rats. Am J Ophthalmol. 1961 May;51:1012–1017. doi: 10.1016/0002-9394(61)91787-1. [DOI] [PubMed] [Google Scholar]
  28. MARIE J., ROYER P., LESTRADET H., ELIACHAR E., RAPPOPORT R. Galactosémie; modalités évolutives et explorations biochimiques dans deux observations. Sem Hop. 1958 May 24;34(24/5):1499–504/P. [PubMed] [Google Scholar]
  29. MARIS L., VALCKE J. La galactosémie; aperçu général et relation d'un cas personnel. Arch Fr Pediatr. 1953;10(1):36–46. [PubMed] [Google Scholar]
  30. PATZ A. Cataracts in galactosemia; observations in three cases. Am J Ophthalmol. 1953 Apr;36(4):453–462. doi: 10.1016/0002-9394(53)90556-x. [DOI] [PubMed] [Google Scholar]
  31. Quan-Ma R., Wells W. W. The distribution of galactitol in tissues of rats fed galactose. Biochem Biophys Res Commun. 1965 Aug 16;20(4):486–490. doi: 10.1016/0006-291x(65)90605-4. [DOI] [PubMed] [Google Scholar]
  32. RITTER J. A., CANNON E. J. Galactosemia with cataracts; report of a case, with notes on physiopathology. N Engl J Med. 1955 May 5;252(18):747–752. doi: 10.1056/NEJM195505052521802. [DOI] [PubMed] [Google Scholar]
  33. SCHREIER K., ACKER R., HENCKEL H. Uber die Galaktosämie Mit einer Erörterung der Besonderheiten des Galaktosestoffwechsels. Z Kinderheilkd. 1957;79(6):666–679. [PubMed] [Google Scholar]
  34. SCHWARZ V., GOLBERG L., KOMROWER G. M., HOLZEL A. Some disturbances of erythrocyte metabolism in galactosaemia. Biochem J. 1956 Jan;62(1):34–40. doi: 10.1042/bj0620034. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. SCHWARZ V., WELLS A. R., HOLZEL A., KOMROWER G. M. A study of the genetics of galactosaemia. Ann Hum Genet. 1961 Dec;25:179–188. doi: 10.1111/j.1469-1809.1962.tb01518.x. [DOI] [PubMed] [Google Scholar]
  36. Schmidt B. J., Ramos A. O., Caldeira J. A., Monteiro D. C. Orotic acid and experimental galactosemia. J Pediatr. 1966 Jan;68(1):138–139. doi: 10.1016/s0022-3476(66)80430-4. [DOI] [PubMed] [Google Scholar]
  37. Segal S., Blair A. SOME OBSERVATIONS ON THE METABOLISM OF D-GALACTOSE IN NORMAL MAN. J Clin Invest. 1961 Nov;40(11):2016–2025. doi: 10.1172/JCI104428. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Segal S., Roth H., Blair A. Observations on the influence of orotic acid on galactose metabolism in congenital galactosemia. J Pediatr. 1966 Jan;68(1):135–138. doi: 10.1016/s0022-3476(66)80429-8. [DOI] [PubMed] [Google Scholar]
  39. TOWNSEND E. H., Jr, MASON H. H., STRONG P. S. Galactosemia and its relation to Laennec's cirrhosis; review of the literature and presentation of six additional cases. Pediatrics. 1951 Jun;7(6):760–773. [PubMed] [Google Scholar]
  40. TURNBULL D. C. Galactosemic cataracts; a report of two cases. Am J Ophthalmol. 1956 Oct;42(4 Pt 1):602–606. [PubMed] [Google Scholar]
  41. VAN HEYNINGEN R. Metabolism of xylose by the lens, 2. Rat lens in vivo and in vitro. Biochem J. 1959 Sep;73:197–207. doi: 10.1042/bj0730197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  42. VARMA S. N., SCHWARZ V., SIMPSON I. M. The role of dietary lactose in the synthesis of brain galactolipids. Biochem J. 1962 Dec;85:546–549. doi: 10.1042/bj0850546. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. WALKER F. A., HSIA D. Y., SLATIS H. M., STEINBERG A. G. Galactosemia: a study of twenty-seven kindreds in North America. Ann Hum Genet. 1962 May;25:287–311. doi: 10.1111/j.1469-1809.1962.tb01767.x. [DOI] [PubMed] [Google Scholar]
  44. WEINBERG A. N., SEGAL S. Effect of galactose-1-phosphate on glucose oxidation by normal and galactosemic leukocytes. Science. 1960 Oct 14;132(3433):1015–1016. doi: 10.1126/science.132.3433.1015. [DOI] [PubMed] [Google Scholar]
  45. WELLS W. W., PITTMAN T. A., EGAN T. J. THE ISOLATION AND IDENTIFICATION OF GALACTITOL FROM THE URINE OF PATIENTS WITH GALACTOSEMIA. J Biol Chem. 1964 Oct;239:3192–3195. [PubMed] [Google Scholar]
  46. WELLS W. W., PITTMAN T. A., WELLS H. J., EGAN T. J. THE ISOLATION AND IDENTIFICATION OF GALACTITOL FROM THE BRAINS OF GALACTOSEMIA PATIENTS. J Biol Chem. 1965 Mar;240:1002–1004. [PubMed] [Google Scholar]
  47. WILSON W. A., DONNELL G. N. Cataracts in galactosemia. AMA Arch Ophthalmol. 1958 Aug;60(2):215–222. doi: 10.1001/archopht.1958.00940080229005. [DOI] [PubMed] [Google Scholar]
  48. WONGIN N. G., BERGREN W. R., DONNELL G. N. GALACTOSE-1-PHOSPHATE URIDYL TRANSFERASE ACTIVITY IN GALACTOSAEMIA. Nature. 1964 Aug 22;203:845–847. doi: 10.1038/203845a0. [DOI] [PubMed] [Google Scholar]

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