Abstract
PURPOSE: To complete the first independent and largest multicenter outcome investigation to analyze the motor and functional results of a series of patients surgically aligned prior to age 6 months and followed for a minimum of 4 years. METHODS: Sixteen patients, surgically aligned at an average age of 4.2 months, were examined at an average of 7.1 years to assess their motor and functional outcomes. RESULTS: Motor and sensory tests showed 11 patients to have a small or negligible motor misalignment at near point with both binocular fusion and gross stereopsis ability. A single patient aligned by 3 months of age demonstrated reproducible refined stereoacuity on sensory testing. However, the patients who achieved alignment by 4 or 5 months did not demonstrate any better quality of binocularity than that found in a previously studied group of patients aligned at 6 months. CONCLUSION: Binocularity that includes refined stereoacuity remains an elusive target and a rare outcome for an ophthalmologist treating congenital esotropia, despite very early surgical alignment.
Full text
PDF![135](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/60d7d6cbb9f4/taos00006-0162.png)
![136](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/f76ec7a79b0b/taos00006-0163.png)
![137](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/f699413e1df8/taos00006-0164.png)
![138](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/e82eb07ee175/taos00006-0165.png)
![139](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/639d5d059895/taos00006-0166.png)
![140](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/ad42efc9b3af/taos00006-0167.png)
![141](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/4e830b37f66e/taos00006-0168.png)
![142](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/e39925697519/taos00006-0169.png)
![143](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/72ea179dc0c7/taos00006-0170.png)
![144](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/8f09b01f29e9/taos00006-0171.png)
![145](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/2e23c95bd50c/taos00006-0172.png)
![146](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7f98/1312054/81a3abf266e3/taos00006-0173.png)
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Archer S. M., Helveston E. M., Miller K. K., Ellis F. D. Stereopsis in normal infants and infants with congenital esotropia. Am J Ophthalmol. 1986 May 15;101(5):591–596. doi: 10.1016/0002-9394(86)90950-5. [DOI] [PubMed] [Google Scholar]
- Crawford M. L., von Noorden G. K. Optically induced concomitant strabismus in monkeys. Invest Ophthalmol Vis Sci. 1980 Sep;19(9):1105–1109. [PubMed] [Google Scholar]
- Crawford M. L., von Noorden G. K. The effects of short-term experimental strabismus on the visual system in Macaca mulatta. Invest Ophthalmol Vis Sci. 1979 May;18(5):496–505. [PubMed] [Google Scholar]
- Crawford M. L., von Noorden G. K. The effects of short-term experimental strabismus on the visual system in Macaca mulatta. Invest Ophthalmol Vis Sci. 1979 May;18(5):496–505. [PubMed] [Google Scholar]
- Helveston E. M., Ellis F. D., Plager D. A., Miller K. K. Early surgery for essential infantile esotropia. J Pediatr Ophthalmol Strabismus. 1990 May-Jun;27(3):115–119. doi: 10.3928/0191-3913-19900501-03. [DOI] [PubMed] [Google Scholar]
- Helveston E. M. Esotropia. Trans Am Ophthalmol Soc. 1988;86:441–460. [PMC free article] [PubMed] [Google Scholar]
- Helveston E. M. Esotropia. Trans Am Ophthalmol Soc. 1988;86:441–460. [PMC free article] [PubMed] [Google Scholar]
- Ing M. R. Early surgical alignment for congenital esotropia. Trans Am Ophthalmol Soc. 1981;79:625–663. [PMC free article] [PubMed] [Google Scholar]
- Ing M. R. Progressive increase in the angle of deviation in congenital esotropia. Trans Am Ophthalmol Soc. 1994;92:117–131. [PMC free article] [PubMed] [Google Scholar]
- Mohindra I., Zwaan J., Held R., Brill S., Zwaan F. Development of acuity and stereopsis in infants with esotropia. Ophthalmology. 1985 May;92(5):691–697. doi: 10.1016/s0161-6420(85)33980-5. [DOI] [PubMed] [Google Scholar]
- Nixon R. B., Helveston E. M., Miller K., Archer S. M., Ellis F. D. Incidence of strabismus in neonates. Am J Ophthalmol. 1985 Dec 15;100(6):798–801. doi: 10.1016/s0002-9394(14)73370-7. [DOI] [PubMed] [Google Scholar]
- Parks M. M. Congenital esotropia with a bifixation result. Report of a case. Doc Ophthalmol. 1984 Aug 15;58(1):109–114. doi: 10.1007/BF00140907. [DOI] [PubMed] [Google Scholar]
- Parks M. M. Congenital esotropia with a bifixation result. Report of a case. Doc Ophthalmol. 1984 Aug 15;58(1):109–114. doi: 10.1007/BF00140907. [DOI] [PubMed] [Google Scholar]
- Parks M. M. Th monofixation syndrome. Trans Am Ophthalmol Soc. 1969;67:609–657. [PMC free article] [PubMed] [Google Scholar]
- Scott M. H., Noble A. G., Raymond W. R., 4th, Parks M. M. Prevalence of primary monofixation syndrome in parents of children with congenital esotropia. J Pediatr Ophthalmol Strabismus. 1994 Sep-Oct;31(5):298–302. doi: 10.3928/0191-3913-19940901-06. [DOI] [PubMed] [Google Scholar]
- Wright K. W., Edelman P. M., McVey J. H., Terry A. P., Lin M. High-grade stereo acuity after early surgery for congenital esotropia. Arch Ophthalmol. 1994 Jul;112(7):913–919. doi: 10.1001/archopht.1994.01090190061022. [DOI] [PubMed] [Google Scholar]
- Wright K. W., Edelman P. M., McVey J. H., Terry A. P., Lin M. High-grade stereo acuity after early surgery for congenital esotropia. Arch Ophthalmol. 1994 Jul;112(7):913–919. doi: 10.1001/archopht.1994.01090190061022. [DOI] [PubMed] [Google Scholar]
- von Noorden G. K. A reassessment of infantile esotropia. XLIV Edward Jackson memorial lecture. Am J Ophthalmol. 1988 Jan 15;105(1):1–10. doi: 10.1016/0002-9394(88)90113-4. [DOI] [PubMed] [Google Scholar]