Skip to main content

. 1982;80:218–234.

The Kearns-Sayre syndrome: a light and electron microscopic study.

R C Eagle Jr, T R Hedges, M Yanoff

PMCID: PMC1312266 PMID: 7182961

218

Images in this article

FIGURE 1 A
on p.221

FIGURE 1 B
on p.221

FIGURE 2
on p.222

FIGURE 3 A
on p.223

FIGURE 3 B
on p.223

FIGURE 4 A
on p.224

FIGURE 4 B
on p.224

FIGURE 5 A
on p.225

FIGURE 5 B
on p.225

FIGURE 6
on p.226

FIGURE 7
on p.227

FIGURE 8
on p.228

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

Bec P., Arne J. L. L'ophtalmoplégie externe progressive et ses associations. A propos d'n cas avec hypertonie oculaire, dégénérescence tapéto-rétinienne etaltérations cardiaques. Arch Ophtalmol Rev Gen Ophtalmol. 1974 Dec;34(12):879–886. [PubMed] [Google Scholar]
Beckerman B. L., Henkind P. Progressive external ophthalmoplegia and benign retinal pigmentation. Am J Ophthalmol. 1976 Jan;81(1):89–92. doi: 10.1016/0002-9394(76)90197-5. [DOI] [PubMed] [Google Scholar]
Berenberg R. A., Pellock J. M., DiMauro S., Schotland D. L., Bonilla E., Eastwood A., Hays A., Vicale C. T., Behrens M., Chutorian A. Lumping or splitting? "Ophthalmoplegia-plus" or Kearns-Sayre syndrome? Ann Neurol. 1977 Jan;1(1):37–54. doi: 10.1002/ana.410010104. [DOI] [PubMed] [Google Scholar]
COGAN D. G. Primary chorioretinal aberrations with night blindness; pathology. Trans Am Acad Ophthalmol Otolaryngol. 1950 Jul-Aug;54:629–661. [PubMed] [Google Scholar]
Celić M., Dorn V., Zeskov P., Raić N. Ophthalmoplegia externa chronica progressiva mit atypischer Netzhautpigmentdystrophie. Klin Monbl Augenheilkd. 1980 Dec;177(6):677–683. [PubMed] [Google Scholar]
Daniele S., Cianchetti C., Cao A. Progressive external ophthalmoplegia associated with retinal pigment epitheliopathy. Am J Ophthalmol. 1975 Oct;80(4):585–590. doi: 10.1016/0002-9394(75)90388-8. [DOI] [PubMed] [Google Scholar]
Daroff R. B., Solitare G. B., Pincus J. H., Glaser G. H. Spongiform encephalopathy with chronic progressive external ophthalmoplegia. Central ophthalmoplegia mimicking ocular myopathy. Neurology. 1966 Feb;16(2):161–169. doi: 10.1212/wnl.16.2_part_1.161. [DOI] [PubMed] [Google Scholar]
Drachman D. A. Ophthalmoplegia plus. The neurodegenerative disorders associated with progressive external ophthalmoplegia. Arch Neurol. 1968 Jun;18(6):654–674. doi: 10.1001/archneur.1968.00470360076008. [DOI] [PubMed] [Google Scholar]
Eagle R. C., Jr, Lucier A. C., Bernardino V. B., Jr, Yanoff M. Retinal pigment epithelial abnormalities in fundus flavimaculatus: a light and electron microscopic study. Ophthalmology. 1980 Dec;87(12):1189–1200. doi: 10.1016/s0161-6420(80)35106-3. [DOI] [PubMed] [Google Scholar]
Eshaghian J., Anderson R. L., Weingeist T. A., Hart M. N., Cancilla P. A. Orbicularis oculi muscle in chronic progressive external ophthalmoplegia. Arch Ophthalmol. 1980 Jun;98(6):1070–1073. doi: 10.1001/archopht.1980.01020031060010. [DOI] [PubMed] [Google Scholar]
Horwitz S. J., Roessmann U. Kearns-Sayre syndrome with hypoparathyroidism. Ann Neurol. 1978 Jun;3(6):513–518. doi: 10.1002/ana.410030611. [DOI] [PubMed] [Google Scholar]
Hyman B. N., Patten B. M., Dodson R. F. Mitochondrial abnormalities in progressive external ophthalmoplegia. Am J Ophthalmol. 1977 Mar;83(3):362–371. doi: 10.1016/0002-9394(77)90735-8. [DOI] [PubMed] [Google Scholar]
KEARNS T. P., SAYRE G. P. Retinitis pigmentosa, external ophthalmophegia, and complete heart block: unusual syndrome with histologic study in one of two cases. AMA Arch Ophthalmol. 1958 Aug;60(2):280–289. [PubMed] [Google Scholar]
Kearns T. P. External Ophthalmoplegia, Pigmentary Degeneration of the Retina, and Cardiomyopathy: A Newly Recognized Syndrome. Trans Am Ophthalmol Soc. 1965;63:559–625. [PMC free article] [PubMed] [Google Scholar]
Koerner F. Pigmentary retinopathy in cases of chronic progressive external ophthalmoplegia. Visual sensory aspects. Trans Ophthalmol Soc U K. 1972;92:251–263. [PubMed] [Google Scholar]
Kolb H., Gouras P. Electron microscopic observations of human retinitis pigmentosa, dominantly inherited. Invest Ophthalmol. 1974 Jul;13(7):487–498. [PubMed] [Google Scholar]
Kuwabara T., Ishikawa Y., Kaiser-Kupfer M. I. Experimental model of gyrate atrophy in animals. Ophthalmology. 1981 Apr;88(4):331–335. doi: 10.1016/s0161-6420(81)35027-1. [DOI] [PubMed] [Google Scholar]
Körner F., Probst I. Typische Retinopathia pigmentosa bei chronisch-progressiver Ophthalmoplegie. Albrecht Von Graefes Arch Klin Exp Ophthalmol. 1975 Jun 6;195(3):195–200. doi: 10.1007/BF00410471. [DOI] [PubMed] [Google Scholar]
LUCAS D. R. Retinitis pigmentosa; pathological findings in two cases. Br J Ophthalmol. 1956 Jan;40(1):14–23. doi: 10.1136/bjo.40.1.14. [DOI] [PMC free article] [PubMed] [Google Scholar]
Leveille A. S., Newell F. W. Autosomal dominant Kearns-Sayre syndrome. Ophthalmology. 1980 Feb;87(2):99–108. doi: 10.1016/s0161-6420(80)35262-7. [DOI] [PubMed] [Google Scholar]
Lowes M. Chronic progressive external ophthalmoplegia, pigmentary retinopathy, and heart block (Kearns-Sayre syndrome). Report of a case. Acta Ophthalmol (Copenh) 1975 Sep;53(4):610–619. doi: 10.1111/j.1755-3768.1975.tb01779.x. [DOI] [PubMed] [Google Scholar]
Metz H. S., Cohen M. Progressive external ophthalmoplegia. Ann Ophthalmol. 1973 Jul;5(7):775–778. [PubMed] [Google Scholar]
Mills P. V., Bowen D. I., Thomson D. S. Chronic progressive external ophthalmoplegia and pigmentary degeneration of the retina. Br J Ophthalmol. 1971 May;55(5):302–311. doi: 10.1136/bjo.55.5.302. [DOI] [PMC free article] [PubMed] [Google Scholar]
Mizuno K., Nishida S. Electron microscopic studies of human retinitis pigmentosa. I. Two cases of advanced retinitis pigmentosa. Am J Ophthalmol. 1967 Apr;63(4):791–803. doi: 10.1016/0002-9394(67)91306-2. [DOI] [PubMed] [Google Scholar]
Reske-Nielsen E., Lou H. C., Lowes M. Progressive external ophthalmoplegia. Evidence for a generalised mitochondrial disease with a defect in pyruvate metabolism. Acta Ophthalmol (Copenh) 1976 Oct;54(5):553–573. doi: 10.1111/j.1755-3768.1976.tb01285.x. [DOI] [PubMed] [Google Scholar]
Ringel S. P., Wilson W. B., Barden M. T. Extraocular muscle biopsy in chronic progressive external ophthalmoplegia. Ann Neurol. 1979 Oct;6(4):326–339. doi: 10.1002/ana.410060406. [DOI] [PubMed] [Google Scholar]
Seigel R. S., Seeger J. F., Gabrielsen T. O., Allen R. J. Computed tomography in oculocraniosomatic disease (Kearns-Sayre syndrome). Radiology. 1979 Jan;130(1):159–164. doi: 10.1148/130.1.159. [DOI] [PubMed] [Google Scholar]
Szamier R. B., Berson E. L., Klein R., Meyers S. Sex-linked retinitis pigmentosa: ultrastructure of photoreceptors and pigment epithelium. Invest Ophthalmol Vis Sci. 1979 Feb;18(2):145–160. [PubMed] [Google Scholar]
Szamier R. B., Berson E. L. Retinal ultrastructure in advanced retinitis pigmentosa. Invest Ophthalmol Vis Sci. 1977 Oct;16(10):947–962. [PubMed] [Google Scholar]
THORSON J. C., BELL W. E. Progressive dystrophic external ophthalmoplegia with abiotrophic fundus changes. Arch Ophthalmol. 1959 Nov;62:833–838. doi: 10.1001/archopht.1959.04220050095015. [DOI] [PubMed] [Google Scholar]
Zintz R., Villiger W. Elektronenmikroskopische Befunde bei 3 Fällen von chronisch progressiver okulärer Muskeldystrophie. Ophthalmologica. 1967;153(6):439–459. doi: 10.1159/000305086. [DOI] [PubMed] [Google Scholar]

ACTIONS

PDF (4.3 MB)

RESOURCES