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International Journal of Molecular Sciences logoLink to International Journal of Molecular Sciences
. 2026 Apr 29;27(9):3976. doi: 10.3390/ijms27093976

RETRACTED: Richards et al. Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC). Int. J. Mol. Sci. 2023, 24, 10545

Cathy E Richards 1,*, Yasir Y Elamin 1,2, Aoife Carr 1, Kathy Gately 3, Shereen Rafee 3, Mattia Cremona 1, Emer Hanrahan 4, Robert Smyth 1, Daniel Ryan 1,5, Ross K Morgan 5, Susan Kennedy 6, Lance Hudson 7, Joanna Fay 8, Kenneth O’Byrne 9, Bryan T Hennessy 1,†, Sinead Toomey 1,†
PMCID: PMC13131995  PMID: 42060675

IJMS is retracting the article titled “Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC)” [1], cited above.

Following publication, concerns were brought to the attention of the Editorial Office regarding the integrity of a figure presented in this publication [1].

In accordance with the journal’s standard procedures, the Editorial Office and Editorial Board conducted an investigation that identified indications of inappropriate editing in Figure 4 and duplication between Figure 3D in [1] and Figure 3D in [2], previously published by a different author group. Although the authors cooperated with the investigation, the explanations and supporting materials provided were not deemed sufficient by the Editorial Board to resolve the identified concerns. As a consequence, the Editorial Board has lost confidence in the reliability of the reported findings and has decided to retract this publication in accordance with MDPI’s retraction policy.

This retraction was approved by the Editor-in-Chief of IJMS.

The authors have been informed of this retraction and have indicated their agreement with this decision.

Footnotes

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References

  • 1.Richards C.E., Elamin Y.Y., Carr A., Gately K., Rafee S., Cremona M., Hanrahan E., Smyth R., Ryan D., Morgan R.K., et al. RETRACTED: Protein Tyrosine Phosphatase Non-Receptor 11 (PTPN11/Shp2) as a Driver Oncogene and a Novel Therapeutic Target in Non-Small Cell Lung Cancer (NSCLC) Int. J. Mol. Sci. 2023;24:10545. doi: 10.3390/ijms241310545. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
  • 2.Engelman J.A., Chen L., Tan X., Crosby K., Guimaraes A.R., Upadhyay R., Maira M., McNamara K., Perera S.A., Song Y., et al. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat. Med. 2008;14:1351–1356. doi: 10.1038/nm.1890. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from International Journal of Molecular Sciences are provided here courtesy of Multidisciplinary Digital Publishing Institute (MDPI)

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