Skip to main content
The British Journal of General Practice logoLink to The British Journal of General Practice
. 2004 Mar;54(500):201–206.

Early detection of COPD in primary care: screening by invitation of smokers aged 40 to 55 years.

Georgios Stratelis 1, Per Jakobsson 1, Siguard Molstad 1, Olle Zetterstrom 1
PMCID: PMC1314831  PMID: 15006126

Abstract

BACKGROUND: The incidence of chronic obstructive pulmonary disease (COPD) is increasing in developed countries, as is the mortality rate. The main cause of COPD is smoking, and COPD is usually diagnosed at a late stage. AIM: To evaluate a method to detect COPD at an early stage in smokers in a young age group (40-55 years). DESIGN OF STUDY: Prospective descriptive study. SETTING: The city of Motala (45,000 inhabitants) and its surrounding rural areas (43,000 inhabitants) in south-east Sweden. Nineteen thousand, seven hundred and fifty subjects were between 40 and 55 years of age. According to Swedish statistics, approximately 27% of this population are smokers. METHOD: Smokers aged between 40 and 55 years were invited to have free spirometry testing in primary healthcare centres. Placards were placed in pharmacies and health centres and advertising was carried out locally twice a year. RESULTS: A total of 512 smokers responded. The prevalence of COPD was 27% (n = 141). The COPD was classified as mild obstruction in 85% (n = 120), moderate in 13% (n = 18) and severe in 2% (n = 3) according to the European Respiratory Society classification. Knowledge of the disease COPD was acknowledged by 39% of the responders to the questionnaire. Logistic regression analysis showed that age, male sex, number of pack years, dyspnoea and symptoms of chronic bronchitis significantly increased the odds of having COPD. The adjusted odds ratio was significant for having > 30 pack years. CONCLUSIONS: This method of inviting relatively young smokers selected a population of smokers with a high incidence of COPD, and may be one way of identifying smokers with COPD in the early stages.

Full Text

The Full Text of this article is available as a PDF (51.3 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Anthonisen N. R., Connett J. E., Kiley J. P., Altose M. D., Bailey W. C., Buist A. S., Conway W. A., Jr, Enright P. L., Kanner R. E., O'Hara P. Effects of smoking intervention and the use of an inhaled anticholinergic bronchodilator on the rate of decline of FEV1. The Lung Health Study. JAMA. 1994 Nov 16;272(19):1497–1505. [PubMed] [Google Scholar]
  2. Britton M. The burden of COPD in the U.K.: results from the Confronting COPD survey. Respir Med. 2003 Mar;97 (Suppl 100):S71–S79. doi: 10.1016/s0954-6111(03)80027-6. [DOI] [PubMed] [Google Scholar]
  3. Ekberg-Jansson A., Andersson B., Bake B., Boijsen M., Enanden I., Rosengren A., Skoogh B. E., Tylén U., Venge P., Löfdahl C. G. Neutrophil-associated activation markers in healthy smokers relates to a fall in DL(CO) and to emphysematous changes on high resolution CT. Respir Med. 2001 May;95(5):363–373. doi: 10.1053/rmed.2001.1050. [DOI] [PubMed] [Google Scholar]
  4. Fletcher C., Peto R. The natural history of chronic airflow obstruction. Br Med J. 1977 Jun 25;1(6077):1645–1648. doi: 10.1136/bmj.1.6077.1645. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Laitinen L. A., Koskela K. Chronic bronchitis and chronic obstructive pulmonary disease: Finnish National Guidelines for Prevention and Treatment 1998-2007. Respir Med. 1999 May;93(5):297–332. doi: 10.1016/s0954-6111(99)90313-x. [DOI] [PubMed] [Google Scholar]
  6. Lundbäck B., Lindberg A., Lindström M., Rönmark E., Jonsson A. C., Jönsson E., Larsson L. G., Andersson S., Sandström T., Larsson K. Not 15 but 50% of smokers develop COPD?--Report from the Obstructive Lung Disease in Northern Sweden Studies. Respir Med. 2003 Feb;97(2):115–122. doi: 10.1053/rmed.2003.1446. [DOI] [PubMed] [Google Scholar]
  7. Peña V. S., Miravitlles M., Gabriel R., Jiménez-Ruiz C. A., Villasante C., Masa J. F., Viejo J. L., Fernández-Fau L. Geographic variations in prevalence and underdiagnosis of COPD: results of the IBERPOC multicentre epidemiological study. Chest. 2000 Oct;118(4):981–989. doi: 10.1378/chest.118.4.981. [DOI] [PubMed] [Google Scholar]
  8. Siafakas N. M., Vermeire P., Pride N. B., Paoletti P., Gibson J., Howard P., Yernault J. C., Decramer M., Higenbottam T., Postma D. S. Optimal assessment and management of chronic obstructive pulmonary disease (COPD). The European Respiratory Society Task Force. Eur Respir J. 1995 Aug;8(8):1398–1420. doi: 10.1183/09031936.95.08081398. [DOI] [PubMed] [Google Scholar]
  9. Walters Nikki, Coleman Tim. Comparison of the smoking behaviour and attitudes of smokers who attribute respiratory symptoms to smoking with those who do not. Br J Gen Pract. 2002 Feb;52(475):132–134. [PMC free article] [PubMed] [Google Scholar]
  10. Zieliñski J., Bednarek M., Know the Age of Your Lung Study Group Early detection of COPD in a high-risk population using spirometric screening. Chest. 2001 Mar;119(3):731–736. doi: 10.1378/chest.119.3.731. [DOI] [PubMed] [Google Scholar]

Articles from The British Journal of General Practice are provided here courtesy of Royal College of General Practitioners

RESOURCES