Simona Esposito
Simona Esposito
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
2
Department of Medicine and Surgery, LUM University, Bari, Italy
1,2,
Augusto Di Castelnuovo
Augusto Di Castelnuovo
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Simona Costanzo
Simona Costanzo
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
3
Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
1,3,
Alessandro Gialluisi
Alessandro Gialluisi
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
2
Department of Medicine and Surgery, LUM University, Bari, Italy
1,2,
Antonietta Pepe
Antonietta Pepe
2
Department of Medicine and Surgery, LUM University, Bari, Italy
2,
Emilia Ruggiero
Emilia Ruggiero
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Amalia De Curtis
Amalia De Curtis
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Sara Magnacca
Sara Magnacca
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Mariarosaria Persichillo
Mariarosaria Persichillo
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Francesc Casanovas-Garriga
Francesc Casanovas-Garriga
4
Department of Internal Medicine, Hospital Clínic de Barcelona, University of Barcelona (UB), Barcelona, Spain
5
Institut de Recerca en Nutrició i Seguretat Alimentaria (INSA-UB), University of Barcelona (UB), Barcelona, Spain
6
Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
4,5,6,
Chiara Cerletti
Chiara Cerletti
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Maria Benedetta Donati
Maria Benedetta Donati
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Giovanni de Gaetano
Giovanni de Gaetano
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1,
Licia Iacoviello
Licia Iacoviello
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
2
Department of Medicine and Surgery, LUM University, Bari, Italy
1,2,*,
Marialaura Bonaccio
Marialaura Bonaccio
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
1
1
Research Unit of Epidemiology and Prevention, IRCCS Neuromed, Pozzilli, Isernia, Italy
2
Department of Medicine and Surgery, LUM University, Bari, Italy
3
Department of Medicine and Surgery, Research Center in Epidemiology and Preventive Medicine (EPIMED), University of Insubria, Varese, Italy
4
Department of Internal Medicine, Hospital Clínic de Barcelona, University of Barcelona (UB), Barcelona, Spain
5
Institut de Recerca en Nutrició i Seguretat Alimentaria (INSA-UB), University of Barcelona (UB), Barcelona, Spain
6
Institut d’Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain
*
Correspondence: Licia Iacoviello, licia.iacoviello@moli-sani.org
This Original Article is part of the IJPH Special Issue “The Effects of Wine in Moderation in the Context of Mediterranean or Other Healthy Diets.”
Received 2026 Apr 1; Revised 2026 Apr 7; Accepted 2026 Apr 9; Collection date 2026.
Keywords: biological aging, mediterranean diet, neurological decline, prevention, wine consumption
Copyright © 2026 Esposito, Di Castelnuovo, Costanzo, Gialluisi, Pepe, Ruggiero, De Curtis, Magnacca, Persichillo, Casanovas-Garriga, Cerletti, Donati, de Gaetano, Iacoviello and Bonaccio.
This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.