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The Journal of Pharmacology and Experimental Therapeutics logoLink to The Journal of Pharmacology and Experimental Therapeutics
. 2025 Jun 11;392(7):103628. doi: 10.1016/j.jpet.2025.103628

Corrigendum to ‘A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption’ [The Journal of Pharmacology and Experimental Therapeutics 392 (2025) 103597]

Christopher M Arian 1, Eimear T O’Mahony 1, Preston K Manwill 2, Tyler N Graf 2, Nicholas H Oberlies 2,3, Nadja B Cech 2,3, John D Clarke 3,4, Jason G Smith 5, Mary F Paine 3,4, Edward J Kelly 1,6, Kenneth E Thummel 1,3,∗
PMCID: PMC13169306  PMID: 40505413

The authors would like to correct an error in Figure 1 of their paper “A gut response: Application of human enteroid monolayers to probe the mechanism of the goldenseal-mediated inhibition of metformin intestinal absorption”, which published in the June 2025 issue of The Journal of Pharmacology and Experimental Therapeutics. Upon investigation, it was noted that the leftmost panel of Figure 1A was inadvertently replicated in the leftmost panel of Figure 1B. This has been corrected in the Figure included herein.

Fig. 1.

Fig. 1

Metformin uptake kinetics. Concentration-dependent kinetics for metformin intracellular uptake (A) and transcellular flux (B) across enteroid monolayers for 3 donors. Data points correspond to uptake values for individual culture replicates. The red lines correspond to the fit of a Michaelis-Menten model (A) or linear model (B) to the data.


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