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Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1969 Apr;33(2):141–147.

Immunofluorescent Studies of Bovine Para-Influenza 3 Virus II. Experimentally Infected Calves

M J Van Der Maaten 1
PMCID: PMC1319400  PMID: 4305759

Abstract

Fluorescent antibody (FA) studies of tissues from three colostrum deprived calves inoculated intranasally with the SF-4 strain of bovine para-influenza 3 (PI-3) virus indicated that these calves developed a mild upper respiratory infection but infected cells were not identified in the lower respiratory tract. Three other calves inoculated intranasally and intratracheally with PI-3 virus developed more severe clinical signs of infection and virus was identified, by FA techniques, in the upper and lower respiratory tract of all three calves and in the spleen of one calf. PI-3 virus was detected in smears of nasal epithelium from five of six calves at some time during the observation period.

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Selected References

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