Abstract
Five sows were inoculated with a cell-cultured, cytopathic strain of the virus of transmissible gastroenteritis (TGE). Two sows were inoculated intramuscularly, and three by the intramammary route. The response was measured by the neutralizing antibody titers in the serum and the milk, and by the protection against experimental challenge of piglets nursing the sows. There were no marked differences in the serum or milk antibody titers resulting after the two methods of inoculation, although milk titers at the time of challenge were higher after intramammary inoculation. Piglets nursing sows inoculated by the intramammary route were protected to a greater extent than those nursing sows inoculated intramuscularly.
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Selected References
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- Cederblad G., Johansson B. G., Rymo L. Reduction and proteolytic degradation of immunoglobulin A from human colostrum. Acta Chem Scand. 1966;20(9):2349–2357. doi: 10.3891/acta.chem.scand.20-2349. [DOI] [PubMed] [Google Scholar]
- Ditchfield J., Pearce H. G., Jolly R. D., Curtis R. A. A viral gastroenteritis of Ontario swine. 1. Clinical illness and recovery of the virus. Can J Comp Med Vet Sci. 1967 Aug;31(8):193–196. [PMC free article] [PubMed] [Google Scholar]
- Djurickovic S., Thorsen J., Duncan J. R., Roe C. K. Transmissible gastroenteritis of swine in Ontario. Can J Comp Med. 1969 Jan;33(1):59–63. [PMC free article] [PubMed] [Google Scholar]
- Lascelles A. K., Outteridge P. M., Mackenzie D. D. Local production of antibody by the lactating mammary gland following antigenic stimulation. Aust J Exp Biol Med Sci. 1966 Apr;44(2):169–180. doi: 10.1038/icb.1966.18. [DOI] [PubMed] [Google Scholar]
- MITCHELL C. A., WALKER R. V., BANNISTER G. L. Studies relating to the formation of neutralizing antibody following the propagation of influenza and Newcastle disease virus in the bovine mammary gland. Can J Microbiol. 1956 May;2(3):322–328. doi: 10.1139/m56-037. [DOI] [PubMed] [Google Scholar]
- Mitchell C. A., Guerin L. F., Pasieka A. E. Antibody production in milk serum after virus instillation of goat mammary gland. I. Responses to influenza virus, mumps virus, and adenovirus 3. Can J Microbiol. 1967 Aug;13(8):1069–1078. doi: 10.1139/m67-143. [DOI] [PubMed] [Google Scholar]
- OUTTERIDGE P. M., ROCK J. D., LASCELLES A. K. THE IMMUNE RESPONSE OF THE MAMMARY GLAND AND REGIONAL LYMPH NODE FOLLOWING ANTIGENIC STIMULATION. Aust J Exp Biol Med Sci. 1965 Jun;43:265–274. doi: 10.1038/icb.1965.25. [DOI] [PubMed] [Google Scholar]
- Pasieka A. E., Guerin L. F., Mitchell C. A. Antibody production in milk serum after virus instillation of goat mammary gland. II. Biochemical isolation and purification of antibody to influenza virus. Can J Microbiol. 1967 Sep;13(9):1195–1201. doi: 10.1139/m67-164. [DOI] [PubMed] [Google Scholar]
- Sarwar M., Campbell B., Petersen W. E. Production of Antibody in Mammary Gland of Pregnant, Non-Lactating and Lactating Cows, Evoked by Polyvalent Antigen with Reference to Dosage and Frequency of Immunization. Can J Comp Med Vet Sci. 1964 Aug;28(8):183–192. [PMC free article] [PubMed] [Google Scholar]
- THOMAS J. A., LECLERC J. [Preliminary research on the obtention of antibodies of the aftosa fever virus in cow's milk after injection of virus into the teat duct (diathelic immunization)]. C R Hebd Seances Acad Sci. 1961 Mar 13;252:1690–1692. [PubMed] [Google Scholar]
- Thorsen J., Macpherson L. W. A study of procine enteroviruses isolated from swine in the Toronto area. I. Isolation and serological grouping of viruses. Can J Comp Med Vet Sci. 1966 Nov;30(11):308–310. [PMC free article] [PubMed] [Google Scholar]