Abstract
A drug-induced lipidosis of the central nervous system of chickens is reported. Membranous cytoplastic neuronal inclusions similar to those seen in Tay-sach's disease in man and in spontaneous or drug-induced disease in swine were seen by electron microscopy. Fat was demonstrated in frozen sections.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Gleiser C. A., Bay W. W., Dukes T. W., Brown R. S., Read W. K., Pierce K. R. Study of chloroquine toxicity and a drug-induced cerebrospinal lipodystrophy in swine. Am J Pathol. 1968 Jul;53(1):27–45. [PMC free article] [PubMed] [Google Scholar]
- HAGEN L. O. Lipid dystrophic changes in the central nervous system in dogs. Acta Pathol Microbiol Scand. 1953;33(1):22–35. doi: 10.1111/j.1699-0463.1953.tb04796.x. [DOI] [PubMed] [Google Scholar]
- Karbe E., Schiefer B. Familial amaurotic idiocy in male German shorthair pointers. Pathol Vet. 1967;4(3):223–232. doi: 10.1177/030098586700400302. [DOI] [PubMed] [Google Scholar]
- Koppang N. Familiäre Glykosphingolipoidose des Hundes (Juvenile Amaurotische Idiotie) Ergeb Allg Pathol Pathol Anat. 1966;47:1–43. [PubMed] [Google Scholar]
- LUFT J. H. Improvements in epoxy resin embedding methods. J Biophys Biochem Cytol. 1961 Feb;9:409–414. doi: 10.1083/jcb.9.2.409. [DOI] [PMC free article] [PubMed] [Google Scholar]
- REYNOLDS E. S. The use of lead citrate at high pH as an electron-opaque stain in electron microscopy. J Cell Biol. 1963 Apr;17:208–212. doi: 10.1083/jcb.17.1.208. [DOI] [PMC free article] [PubMed] [Google Scholar]
- RIBELIN W. E., KINTNER L. D. Lipodystrophy of the central nervous system in a dog; a disease with similarities to Tay-Sachs disease of man. Cornell Vet. 1956 Oct;46(4):532–537. [PubMed] [Google Scholar]
- Read W. K., Bridges C. H. Cerebrospinal lipodystrophy in swine. A new disease model in comparative pathology. Pathol Vet. 1968;5(1):67–74. doi: 10.1177/030098586800500108. [DOI] [PubMed] [Google Scholar]
- TERRY R. D., WEISS M. Studies in Tay-Sachs disease. II. Ultrastructure of the cerebrum. J Neuropathol Exp Neurol. 1963 Jan;22:18–55. doi: 10.1097/00005072-196301000-00003. [DOI] [PubMed] [Google Scholar]
- Wallace B. J., Schneck L., Kaplan H., Volk B. W. Fine structure of the cerebellum of children with lipidoses. Arch Pathol. 1965 Nov;80(5):466–486. [PubMed] [Google Scholar]