Abstract
Milk whey from immunized sows increased the survival time of gnotobiotic piglets infected with Escherichia coli. The survival time of infected piglets fed milk whey from non-vaccinated sow's was the same as that of similar pigs fed condensed cow milk.
The significance of milk antibodies in immune protection against E. coli enteritis is discussed and compared with that of absorbed colostral antibodies. From calculations presented it would appear that seven day old piglets receive approximately 1 g of gamma globulin daily from milk and that this is equal to the piglets total serum gamma globulin content. After seven days of age the gamma globulin content of piglet serum falls, whereas that of milk remains constant; milk is, therefore, potentially a major source of immunoglobulins with protective activity against E. coli associated enteritides.
Full text
PDF




Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Alexander T. J., Miniats O. P., Ingram D. G., Thomson R. G., Thackeray E. L. Gnotobiotic pigs: procurement, microbial flora, serum proteins and lymphatic tissues. Can Vet J. 1969 Apr;10(4):98–105. [PMC free article] [PubMed] [Google Scholar]
- Cartwright S. F. Transmissible gastro-enteritis of swine (TGE). Br Vet J. 1969 Aug;125(8):410–413. doi: 10.1016/s0007-1935(17)48811-7. [DOI] [PubMed] [Google Scholar]
- Djurickovic S., Thorsen J. Experimental immunisation of sows against transmissible gastroenteritis. I. Immunisation with a bacteria-free suspension of transmissible gastroenteritis virus prepared from the intestines of infected pigs. Vet Rec. 1970 Jul 18;87(3):62–64. doi: 10.1136/vr.87.3.62. [DOI] [PubMed] [Google Scholar]
- Kohler E. M., Bohl E. H. Studies of Escherichia coli in gnotobiotic pigs 3. Evaluation of orally administered specific antisera. Can J Comp Med Vet Sci. 1966 Aug;30(8):233–237. [PMC free article] [PubMed] [Google Scholar]
- Kohler E. M. Studies of escherichia coli in gnotobiotic pigs. IV. Comparison of enteropathogenic and nonenteropathogenic strains. Can J Comp Med Vet Sci. 1967 Nov;31(11):277–282. [PMC free article] [PubMed] [Google Scholar]
- LECCE J. G., MATRONE G., MORGAN D. O. The effect of diet on the maturation of the neonatal piglet's serum protein profile and resistance to disease. Ann N Y Acad Sci. 1961 Aug 31;94:250–264. doi: 10.1111/j.1749-6632.1961.tb35545.x. [DOI] [PubMed] [Google Scholar]