Abstract
Tests were carried out on the efficacy of Cambendazole (5-isopropoxy carbonylamino-2-(4-thiazolyl) benzimidazole) against lungworm and gastrointestinal parasites of calves and lambs. Against Dictyocaulus viviparus the compound was highly effective (80%) against mature worms at levels of 35 mg/kg and over and immature “arrested” worms at 60 mg/kg (71% efective).
In the Calves the compound was very effective (90 to 99%) against adult Haemonchus placei, Ostertagia spp., Trichostrongylus axei and Cooperia oncophora at all levels tested (15, 20, 25, 30, 40 and 60 mg/kg). Against adult Nematodirus spp. dosages of 30, 40 and 60 mg/kg were 81%, 94% and 99% effective respectively
Against arrested Ostertagia spp. larvae, a dosage of 60 mg/kg was 90% effective. Immature stages of Cooperia spp. were susceptible at all levels used but those of Nematodirus spp. required levels of 60 mg/kg for 99% removal.
In the lambs the compound was highly effective against immature and mature nematodes when given orally at all levels tested from 15 mg/kg to 30 mg/kg. Significant reductions (81%) in Moniezia expansa scolices were also observed at dosages from 15 mg/kg to 30 mg/kg.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Baker N. F., Walters G. T. Anthelmintic efficacy of cambendazole in cattle. Am J Vet Res. 1971 Jan;32(1):29–33. [PubMed] [Google Scholar]
- Egerton J. R., Campbell W. C. The efficacy of 5-isopropoxy-carbonylamino-2-(4-thiazolyl) benzimidazole against helminths of sheep. Res Vet Sci. 1970 Mar;11(2):193–195. [PubMed] [Google Scholar]
- Egerton J. R., Eary C. H., Lanza G. R., Wombolt T. H., Campbell W. C. The efficacy of cambendazole against gastrointestinal nematodes of cattle. Res Vet Sci. 1970 Sep;11(5):495–499. [PubMed] [Google Scholar]
- Gupta R. P., Gibbs H. C. Epidemiological investigations on Dictyocaulus viviparus (Bloch, 1782) infection in cattle. Can Vet J. 1970 Aug;11(8):149–156. [PMC free article] [PubMed] [Google Scholar]
