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. 2026 May 22;7(5):692–703. doi: 10.1302/2633-1462.75.BJO-2025-0127.R1

Primary anterior cruciate ligament reconstruction in female athlete-specific literature lacks standardization in outcome reporting

a scoping review

Brian Gibbs 1,✉, Aikaterini Eleftheriadou 2, Jayson Saleet 1, Miho J Tanaka 3, Xinning Li 1, Khalid Al-Hourani 2
PMCID: PMC13196632  PMID: 42171509

Abstract

Aims

Female athletes sustain anterior cruciate ligament (ACL) ruptures at higher rates than male athletes. There is limited literature focusing on outcomes after ACL reconstruction (ACLR) in this population. The purpose of this study was to conduct a scoping review into female-specific literature for primary ACLR procedure, and to ascertain the variability in reporting outcomes in the literature. ‘Female’ was defined as sex assigned at birth for the purposes of this study.

Methods

The systematic review was conducted according to PRISMA, and also used Arksey and O’Malley’s established five-stage process for scoping reviews to map the literature for primary ACLR in female-specific literature. After screening, data were extracted and mapped to provide a descriptive and thematic analysis.

Results

A total of 1,172 studies were identified from the initial search with 16 studies eligible for final scoping review published from 2004 to 2024. Studies were identified from eight countries, with 9/16 (56.3%) from the USA. The mean age was 23.4 years (16 to 32). Key variables such as graft type (7/16, 43.8%) and graft diameter (2/16, 12.5%) were significantly under-reported. Of the functional outcomes, Tegner Activity Score was reported in seven studies (7/16, 43.8%), the International Knee Documentation Committee Score (IKDC) in six studies (6/16, 37.5%), and the Knee Injury and Osteoarthritis Outcome Score (KOOS) in six studies (6/16, 37.5%). Overall, 25 clinical outcomes were recorded spanning all studies including graft re-rupture (4/16, 25.0%), Lachman’s score (3/16, 18.8%), pivot shift (4/16, 25.0%), and return to sport (5/16, 31.3%).

Conclusion

This review identified 16 studies which analyzed female-specific literature for primary ACLR over the last 20 years. There is a significant lack of studies in the literature reporting on female-specific outcomes, and in the eligible studies, there was a significant lack of standardization of variable and outcome reporting.

Cite this article: Bone Jt Open 2026;7(5):692–703.

Keywords: ACL, Knee, Female, Outcomes, primary anterior cruciate ligament reconstruction, anterior cruciate ligament (ACL) reconstructions (ACLR), Knee Injury and Osteoarthritis Outcome Score (KOOS), International Knee Documentation Committee Score, re-rupture, clinical outcomes, functional outcomes, graft diameter, Tegner Activity Score, anterior cruciate ligament (ACL) ruptures

Introduction

Approximately 400,000 anterior cruciate ligament (ACL) reconstructions (ACLR) occur in the USA every year, with this injury being three to eight times higher in the female population compared with males.1-4 Furthermore, the risk of re-rupture and revision surgery in the female population is also higher.5 With the rate of female participation in both recreational and college sports expected to rise, and with the significant investment in female professional sport, this discrepancy in rate of injury is likely to amplify.6

Sex discrepancies in the incidence of ACL injury, clinical outcomes, complication, and revision rates following reconstruction in the female athlete are not completely understood. Several factors have been proposed as being contributory to these discrepancies, including anatomical, biomechanical, endocrine, and sport-specific.7,8 Anatomical factors that may increase risk of re-rupture include a higher Q-angle, smaller femoral notch, increased tibial torsion, increased posterior tibial slope, quadriceps dominance, diameter of hamstrings tendons, and collagen content of tendons. Literature also reports a significant impact on landing mechanics leading to poorer postural control and dynamic knee valgus on landing, thereby increasing strain on the native ACL.9,10 Additionally, more attention has been paid recently to hormonal variations as a result of the menstrual cycle and their effects on injury rates.11 Furthermore, the cyclical variations in the hormones progesterone, oestrogen, and relaxin have been shown to have an effect on ACL metabolism, particularly during days 21 to 24 of the menstrual cycle, representing a time of increased ACL injury risk.12 Certain sports may represent an added risk, with contact sports such as soccer and netball representing a particular risk,13 in comparison to sports such as lacrosse.14

Despite the recognized issues and rising concern of ACL injuries in female athletes, a recent study highlighted that annual publication of female-specific studies was around eight times less than that of male publications in sports science and in the sports medicine literature.15 Additionally, as a result of the aforementioned higher risks and complications surrounding female ACL injuries, it is important to consider females as a distinct group from males. The aim of this study is to provide a methodologically robust scoping review to map the available literature surrounding female-only studies in primary ACLR, adding to the focus on female-specific literature. This review should further inform evidence-based practice, and systematically identify the gaps in reporting criteria.

Methods

The five-stage scoping review process proposed by Arksey and O’Malley16 was adopted, with the recommended adaptations by the Joanna Briggs Institute incorporated.17 This protocol has been previously published by Makaram et al.18 This study was conducted in line with the PRISMA extension for Scoping Reviews (PRISMA-ScR) guidelines.19 The five-stage process was conducted as follows:

Stage 1: Determining the research question

The authors aimed for a broad research question in order to capture as much data as possible in relation to the aim. Therefore, the research question formulated was: what studies have been published with regard to female-specific outcomes in primary ACLR? This would allow capture of the population, variables, and outcomes required to address the aim of the study.

Stage 2: Identifying relevant studies

For this scoping review, the term ‘female’ related to sex assigned at birth. Inclusion and exclusion criteria to delineate eligible studies is summarized in Table I. MEDLINE via PubMed was searched from inception to 1 August 2024. Grey literature sources such as OpenGrey were reviewed, but did not yield any relevant results. Additional articles were sought by reviewing the reference lists on applicable articles. The following medical subject headings (MeSH) and terms were used in our search strategy: (acl) OR (anterior cruciate ligament) AND ((repair) OR (reconstruction)) and ((outcome) OR (measure) OR (strength) OR (stability) OR (range of motion)) AND ((female) OR (girl) OR (female population)). Studies were limited to the English language. A PRISMA flow diagram is presented in Figure 1. After removal of duplicates, three authors (BG, JS, KAH) independently screened the remaining titles and abstracts against the earlier defined eligibility criteria. Differences were resolved by consensus.

Table I.

Study inclusion and exclusion criteria.

Inclusion criteria Exclusion criteria
Anterior cruciate ligament tears Individual case reports, opinion pieces, and narrative reviews
Studies involving skeletally mature (aged 16 years) patients only Studies including paediatric patients (aged < 16, skeletally immature)
Studies involving female athletes only Studies including male athletic population
Studies not describing outcomes of operative management
Studies written in a primary language other than English

Fig. 1.

Flowchart of study selection: 1172 records screened after removing 4 duplicates; 1137 excluded; 35 reports assessed; 19 excluded for various reasons; 16 studies included. A flow diagram shows the process of identifying and selecting studies for a review. Records were identified from MEDLINE via PubMed, with 4 duplicate records removed before screening. A total of 1172 records were screened, and 1137 records were excluded at this stage. Then, 35 reports were sought for retrieval, with none reported as not retrieved. All 35 reports were assessed for eligibility. Of these, 19 reports were excluded for specific reasons: 13 had irrelevant outcome measures, 3 had full text unavailable, 2 were review articles, and 1 was a non-English manuscript. The process resulted in 16 studies included in the review, corresponding to 16 reports.

PRISMA diagram for study selection.

Stage 3: Study selection

After removal of duplicates, two authors (BG, JS) independently screened the remaining titles and abstracts against the earlier defined eligibility criteria. A third senior reviewer (KAH) then completed the screening process with a random selection of 10% of the articles remaining after initial duplicates were removed in order to validate concordance with the inclusion/exclusion decision making. Differences were resolved by consensus after full-text review.

Stage 4: Charting the data

Data were extracted and tabulated by two reviewers (BG, JS), who analyzed all included studies. Data from each study were charted and these were tabulated into both a priori categories and emerging themes to include: study characteristics (study type, level of evidence, country, and year), patient demographic details, variables reported (including data on graft type, cost, processing, sterilization, and storage), and outcomes reported (functional and clinical) (Table II). This was charted into a heat map (Figure 2) for ease of analysis and to give a gross impression of the results. Any discrepancies were resolved via consensus following consultation with a senior author (KAH), who also checked > 10% (4/35) of the eligible articles for accuracy of data extraction. Accuracy was confirmed by reviewing the article and confirming that all data points measured in each study were included in the heatmap created to track outcome variables.

Table II.

Variables which may critically influence outcomes that were collected in the assessment of reporting standards.

Study design:
Study conducted in accordance with CONSORT, STROBE, or PRISMA guidelines
Patient-based details:
Age
BMI
Laterality
Activity or competition level
Prior injury to knee
Injury management details:
Timing from injury to surgery
Length of follow-up postoperatively
Associated injury to ipsilateral knee
Activity during injury
Use of physical therapy prior to ACL repair
Graft type
Graft size
Repair technique
Concomitant treatment of meniscal injury
Secondary outcome measure - Quality of reporting of clinical and patient -reported outcomes following management of ACL tear in female athletes:
Clinical outcomes described:
Reinjury or retear
Failure method
Time to failure
Reoperation rate
Osteoarthritis on postoperative radiograph
Lachman’s test
Pivot shift test
KT-2000 Stress test
Pain with acitivity
Pain with kneeling
Active position sense accuracy
Dynamic position sense
Reaction time
Passive position sense accuary
EMG
Ankle dorsiflexion
Hip and knee mechanics during jumping
Tibiofemoral compressive force
Muscle forces at compression
Isokinetic strength
Goniometric flexion angle
One leg rise
Triple single leg hop
Return to sport
Time to return to sport
Patient-reported outcome measures described:
Tegner activity store
IKDC scores
Lysholm scores
KOOS scores
Kujala scores
VAS
KSES score
ACL-RSI score
TSK-11 score
Joint laxity
Marx activity score
SF36
Patient satisfaction rate

ACL, anterior cruciate ligament; ACL-RSI, anterior cruciate ligament return to sport after injury; EMG, electromyography; IKDC, International Knee Documentation Committee; KOOS, Knee Injury and Osteoarthritis Outcome Score; KSES, Knee Self-Efficacy Scale; STROBE, Strengthening the Reporting of Observational Studies in Epidemiology; TSK-11, Tampa Scale of Kinesiophobia-11; VAS, visual analogue scale.

Fig. 2.

Matrix showing which study variables were reported across multiple studies, with rows for outcomes and demographics and columns for authors; filled cells indicate reported items and empty cells indicate missing data. A large grid-style table summarises reporting across multiple studies listed in columns by author and year. Rows represent categories of variables including patient demographics, injury and treatment details, patient-reported outcomes, re-injury outcomes, and clinical measures. Each cell in the matrix indicates whether a specific variable was reported in a given study. The variables include age, body measures, injury characteristics, surgical details, functional scores such as IKDC and KOOS, return-to-sport timing, reoperation and failure outcomes, and clinical assessments such as joint laxity, strength, and movement tests. The table shows that reporting is inconsistent across studies, with many variables frequently unreported while some commonly used outcomes and basic demographics appear more often.

Heatmap demonstrating data reported in each study, stratified into patient demographic details, variables reported, and outcomes reported. ACL-RSI, anterior cruciate ligament-return to sport after injury; EMG, electromyography; IKDC, International Knee Documentation Committee; KOOS, Knee Injury and Osteoarthritis Outcome Score; KSES, Knee Self-Efficacy Scale; OA, osteoarthritis; PT, physical therapy; RTS, return to sports; SF-36, 36-Item Short-Form Health Survey questionnaire; TSK-11, Tampa Scale of Kinesiophobia-11; VAS, visual analogue scale; WNBA, Women’s National Basketball Association; XR, X-ray.

Stage 5: Collating, summarizing, and reporting results

Analysis and summarization of data was grouped into two domains: the first was descriptive analysis, outlining basic data pertaining to study characteristics as outlined in stage 4. The second domain was thematic summary, as per the a priori categories in stage 4 and their relation to the aim of the study and the broad research question posed in stage 1. These were mapped out accordingly into four main themes: 1) patient demographic details; 2) study independent variables; 3) patient-reported outcomes; and 4) clinical outcome reporting (Figure 2).

Results

Descriptive analysis

The screening process is outlined in Figure 1. A total of 1,172 studies were identified from two different databases (MEDLINE and PubMed). From these, 35 studies were isolated after removing duplicates, and were screened using a title and abstract keyword search, through which 1,137 studies were excluded due to not meeting the inclusion criteria. The remaining 35 studies were then subjected to full-text screening, 19 of which were excluded for reasons such as irrelevance, language, and lack of full-text accessibility. Following the screening process, 16 studies were identified as eligible to be included in final analysis. A summary of each study can be found in Table III.

Table III.

Full-text articles eligible for final analysis.

Authors Journal Year LOE Country Study design Objective
Namdari et al20 The Physician and Sports Medicine 2011 3 USA Cohort To compare athletes who underwent ACL reconstruction with pre-injury and matched controls to determine differences in performance and return to play.
Shakked et al21 Journal of Knee Surgery 2017 3 USA Cohort To evaluate patient-reported outcomes, objective knee stability, complication rates, and the incidence of failure after ACL reconstruction using bone–patellar tendon–bone autograft compared with hamstring autograft in young female patients.
Littmann et al22 Journal of Sport Rehabilitation 2012 4 USA Cross-sectional To compare proprioception of knee movement in women with ACLR and healthy controls.
Stanley et al23 Research in Sports Medicine 2019 3 USA Cohort To examine associations between ankle dorsiflexion displacement and knee and hip kinematics and kinetics during a jump-landing task in females following anterior cruciate ligament reconstruction.
Tsai et al24 American Journal of Sports Medicine 2013 4 USA Controlled laboratory study To examine whether muscle co-contraction and tibiofemoral compressive forces in females after undergoing ACLR can be reduced through the use of a landing strategy that emphasizes greater hip and knee flexion.
Briem et al25 Knee Surgery, Sports Traumatology, Arthroscopy 2016 3 Iceland Cohort To assess activation patterns of medial versus lateral hamstrings in female athletes who had undergone ACL reconstruction using a hamstrings-graft during single-limb functional testing.
Vairo et al26 Arthroscopy: The journal of arthroscopic and related surgery 2013 4 USA Therapeutic study, case series 1) To profile the standing flexion angle and its association with subjective outcomes in ipsilateral hamstring tendon autograft anterior cruciate ligament reconstructed patients. 2) To describe prone position measured hamstring strength as a predictor of flexion angle.
Guzzini et al27 International Orthopedics 2016 3 Italy Cohort To report subjective and objective outcomes after combined ACL and lateral extra-articular tenodesis with a minimum 4-year follow-up in a selected high-risk population of elite female football players.
Hill et al28 American Journal of Sports Medicine 2005 2 Australia RCT To determine whether reinforcement of the tibial fixation would reduce the increased laxity seen in female patients undergoing ACL reconstruction using hamstring tendon graft.
Lohmander et al29 Arthritis and Rheumatism 2004 3 Sweden Cohort To determine the prevalence of radiological knee osteoarthritis as well as knee-related symptoms and functional limitations in female soccer players 12 years after an anterior cruciate ligament injury.
Tiplady et al30 American Journal of Sports Medicine 2023 2 New Zealand Cohort To assess the effect of graft choice on ACL reconstruction failure rates among young women in New Zealand.
Ezzat et al31 American Journal of Sports Medicine 2021 3 Canada Cohort 1) To assess whether female youth and young adults who have had ACLR in the previous 1 to 2 years would have less moderate or vigorous physical activity compared with healthy matched controls. 2) To assess if the ACLR group would report lower levels of sports participation, patient-reported health outcomes, and physical function.
Allen et al32 American Journal of Sports Medicine 2016 3 USA Cohort To 1) report the rates of subsequent ACL injury (ipsilateral graft rupture or contralateral tear) in competitive female soccer players; 2) compare these rates with those of other female athletes of similar competitive level; 3) determine risk factors for second ACL injury; and 4) report clinical outcome scores in this population.
Lee et al33 Orthopaedic Journal of Sports Medicine 2023 3 South Korea Cohort To evaluate the results of combined ACLR and anterolateral ligament reconstruction in young females with a high-grade pivot shift (grade 2).
Tramer et al34 Orthopaedic Journal of Sports Medicine 2020 3 USA Cohort To quantify RTP rates and performance after ACL reconstruction in WNBA athletes.
Zarzycki et al35 Sports Health 2024 3 USA Secondary analysis of RCT To assess whether greater kinesiophobia, less knee confidence, and lower psychological readiness would be associated with second ACL injury.

ACL, anterior cruciate ligament; ACLR, anterior cruciate ligament reconstruction; LOE, level of evidence; RCT, randomized controlled trial; RTP, return to play; WNBA, Women's National Basketball Association.

The distribution of the 16 studies by the year of publication can be seen in Figure 3. The studies span from 2004 to 2024, with all articles published in the last 20 years, and 10/16 (62.5%) published in the last ten years.

Fig. 3.

Bar chart of publications by year shows mostly one publication per year, with increases to two in 2013 and 2023 and a peak of three in 2016. A bar chart displays the number of publications for selected years between 2004 and 2024. The horizontal axis lists years including 2004, 2005, 2011, 2012, 2013, 2016, 2017, 2019, 2020, 2021, 2023, and 2024, while the vertical axis shows publication counts from zero to three. Most years have one publication, specifically 2004, 2005, 2011, 2012, 2017, 2019, 2020, 2021, and 2024. There are increases to two publications in 2013 and 2023. The highest value occurs in 2016 with three publications. Overall, the chart shows a generally low and steady output with occasional peaks.

Number of publications per year reporting on primary anterior cruciate ligament reconstruction in females.

Studies were identified from eight countries, with 9/16 (56.3%) from the USA and the remaining 7/16 (43.7%) from other countries, including Australia, Republic of Korea, Canada, Iceland, Italy, New Zealand, and Sweden.

The type of sport studied in the included studies is outlined in Figure 4. Two studies (2/16, 12.5%) analyzed more than one sport. The most frequently analyzed sports were soccer and basketball (4/16 studies for each, 25.0%); volleyball and handball were assessed in separate studies (1/16, 6.25%). Eight studies did not assess type of sport (8/16, 50.0%).

Fig. 4.

Bar chart comparing publications by sport shows the highest count for no sport, moderate counts for basketball and soccer, and lower counts for multiple sports, volleyball, and handball. A bar chart illustrates the number of publications by sport category. The horizontal axis lists categories: no sport, multiple sports, basketball, soccer, volleyball, and handball, while the vertical axis shows publication counts from zero up to eight. The no sport category has the highest value at eight publications. Basketball and soccer each have four publications. Multiple sports has two publications. Volleyball and handball each have one publication. The distribution shows that publications are most concentrated in the no sport category, with smaller but notable contributions in basketball and soccer, and relatively few publications in the remaining categories.

Type of sport reported in studies reporting on primary anterior cruciate ligament reconstruction in females.

The classification of the included studies is outlined in Figure 5. Out of the included studies, 15/16 (93.75%) were primary studies and 1/16 (6.25%) was a secondary study. Of the primary studies, 9/16 (56.25%) were cohort studies, 2/16 (12.5%) were case-control studies, 1/16 (6.25%) was a randomized controlled trial (RCT), 2/16 (12.5%) were cross-sectional studies, and 1/16 (6.25%) was a controlled laboratory study. The single secondary study was a secondary analysis of a prospective randomized trial.

Fig. 5.

Bar chart of publications by study type shows cohort studies dominate with nine, while cross sectional and case-control have two each, and RCT, controlled laboratory, and secondary RCT have one each. A bar chart presents the number of publications by study type along the horizontal axis, including cohort, RCT, cross sectional, case-control, controlled laboratory study, and secondary analysis of RCT. The vertical axis shows counts from zero to ten. Cohort studies have the highest number of publications at nine. Cross sectional and case-control studies each have two publications. Randomised controlled trials, controlled laboratory studies, and secondary analyses of RCTs each have one publication. The overall pattern indicates a strong predominance of cohort studies, with relatively limited representation of other study designs.

Type of study reporting on primary anterior cruciate ligament reconstruction in females. RCT, randomized controlled trial.

Level of evidence (LoE) was determined in accordance with the Oxford Centre for Evidence Based Medicine Levels of Evidence.36 The distribution of studies by LoE can be seen in Figure 6. There were 2/16 (12.5%) studies at level II evidence, 11/16 (68.75%) at level III, and 3/16 (18.75%) at level IV.

Fig. 6.

Bar chart of publications by level of evidence shows most at level 3, with fewer at level 4 and the least at level 2. A bar chart presents the number of publications by level of evidence, with levels 2, 3, and 4 shown along the horizontal axis and counts up to twelve on the vertical axis. Level 3 has the highest number of publications at eleven, indicating a strong concentration in this category. Level 4 has three publications, while level 2 has two publications, making it the least represented. The overall pattern shows that most studies fall within level 3 evidence, with comparatively fewer studies at levels 2 and 4.

Level of evidence for studies reporting on primary anterior cruciate ligament reconstruction in females.

Given the heterogeneity in study parameters as described above, and the remit of this scoping review, no formal quality assessment of the studies was attempted, as this fell outside the remit of the aim and broad research question.

Thematic analysis

A representative heatmap for patient demographic details is shown in Figure 2. The sample size of female patients with ACLR ranged from 10 to 180. The most frequently reported demographic characteristics were participant age and BMI, documented in 14/16 and 10/16 studies, respectively. The range of patient age was 16 to 32 years, with 14/16 studies including patient age with a mean age of 23.4 years. The mechanism of injury and activity during injury was rarely reported, with both metrics being recorded in 3/16 (18.8%) studies. Details on prior knee injury reported in 1/16 studies (6.25%) were largely excluded. BMI was noted in 10/16 studies (62.5%), and height and weight were reported in 5/16 (31.3%) and 6/16 (37.%) studies, respectively.

The most commonly reported independent study variable with patient demographic details was the type of graft used for primary ACLR with 7/16 studies (43.8%). Two of these studies analyzed one graft type (2/16, 12.5%), with the remaining five studies analyzing more than one graft type (5/16, 31.3%). A total of 1,677 patients had graft type reported: the majority underwent hamstrings autograft (1,007/1,677, 60.0%), followed by BTB autograft (562/1,677, 33.5%), with the remainder being allograft reconstruction (108/1,677, 6.5%). In comparison, another important graft characteristic, namely graft diameter, was only reported in 2/16 studies (12.5%).

A total of 13 functional outcomes were reported across the studies. The most commonly reported outcomes were patient-reported outcome measures, namely the Tegner Activity Score in seven studies (7/16, 43.8%),37 the International Knee Documentation Committee Score (IKDC) in six studies (6/16, 37.5%),38 and the Knee Injury and Osteoarthritis Outcome Score (KOOS) score also in six studies (6/16, 37.5%).39 There were no functional outcomes reported in three studies (3/16, 18.8%).

In total, 25 clinical outcomes were recorded across the studies. Clinical outcomes were widely under-reported. This includes graft re-rupture (4/16, 25.0%), Lachman’s score (3/16, 18.8%), pivot shift (4/16, 25.0%), and return to sport (5/16, 31.3%).

Discussion

This scoping review is the first to thematically and descriptively assess reporting standards for female athlete-specific primary ACLR literature. Additionally, it has mapped out the breadth of reporting standards and ascertained the variability in the reporting of key variables and outcomes. To the best of the authors’ knowledge, this is the first scoping review to assess this aim.

Clinical variables

While this scoping review has served to highlight the deficiency in key reporting outcomes, it is important to assess key clinical and functional variables. In this review, it was observed that just under half the studies in the literature reported on type of graft used. In a New Zealand ACL registry study by Tiplady et al,30 data were prospectively captured on 1,261 primary ACLRs in young females between 2014 and 2022, noting a higher rate of hamstrings autograft use (63%), compared with bone-patellar tendon-bone graft (37%), with a subsequent higher failure rate seen in the hamstrings group (7.7% vs 1.1%). A further 2023 study by Zarzycki et al35 analyzed 39 high-level female athletes and their psychological readiness for return to sport; 18 female athletes underwent hamstrings soft-tissue autograft, 16 bone-patellar tendon-bone (BTB) autograft, and five patients underwent allograft reconstruction. Nine patients sustained a re-rupture of their graft within two years, all of whom underwent hamstrings autograft reconstruction. It was noted that these patients had an earlier return to sports and psychological readiness to return, and it was recommended that those female athletes who display earlier psychological readiness to return to sport should be delayed. Furthermore, a key graft characteristic, namely graft diameter, was only reported in two studies. Tiplady et al30 noted a mean BTB autograft diameter of 9.8 mm, with mean hamstrings autograft of 8.1 mm. In the only other study recording graft diameter, Hill et al28 observed a median diameter of hamstrings tendon autograft of 7.5 mm (6.5 to 8), in a study of 56 females assessing supplementary tibial fixation on outcomes. There was a discernible paucity in the reporting of other independent study variables (Figure 2).

Clinical and functional outcomes

The three most commonly reported functional outcomes, namely Tegner, IKDC, and KOOS, were also reported in under half the studies included. Littmann et al22 assessed 11 females who had undergone ACLR compared to 20 who had not. In a comprehensive assessment of patient-reported function, while there was no difference in Tegner activity score between the groups, there was a clear, significantly lower IKDC score in those who had undergone ACLR. Additionally, in particular domains of the KOOS score (pain, quality of life, symptoms, and sport/recreation), there was a significantly lower score noted in those who had undergone ACLR compared with controls. This was also backed by a larger study of 180 female ACLR patients who were compared with athletes of a similar competitive level, and noted no difference in IKDC or Tegner scores at latest follow-up.32 Briem et al25 compared 18 ACLR female patients with 18 control patients and only found a lower KOOS score for the symptoms sub-scale at latest six-year follow-up. Vairo et al26 compared 15 hamstring autograft ACLR female patients with 15 healthy controls, and noted a lower KOOS for the pain and sports/recreation sub-scales, supporting the work by Littmann et al.22 Shakked et al21 assessed 66 young female patients (aged 15 to 25 years), 37 of whom underwent BTB autograft ACLR, and 28 hamstrings autograft ACLR. While there was a lower graft re-rupture rate noted in the BTB group, there was no significant difference noted in Tegner or IKDC scores. The KOOS score was not assessed.21

Of the 25 clinical outcomes reported, those of graft re-rupture, Lachman’s score, pivot shift, and return to sport were reported in under one-third of all included studies. Hill et al28 randomized 56 female patients undergoing hamstrings autograft ACLR into two groups, to assess whether supplementary fixation of the graft on the tibial side (staple) led to an effect on outcomes. At two-year follow-up, a significant difference favoured the supplementary tibial fixation group for Lachman’s grading, but no difference between the groups was noted for pivot shift grade.28 All studies included which assessed graft re-rupture rate favoured BTB autograft ACLR over hamstrings autograft ACLR, with this being most pronounced in the national New Zealand registry study by Tiplady et al,30 as described earlier.

The main message of this scoping review is the considerable lack of reporting and, when reporting is available, the lack of standardized reporting for variables and outcomes in female-specific ACLR literature. Scoping reviews are designed to identify the types of available evidence in a given field, identify the key characteristics related to the concept at hand, highlight potential knowledge gaps, clarify concepts in the literature, and provide a precursor to systematic reviews.40 This is particularly important in female-specific literature in recognition of the significant differences in both ACL injury rates, as well as postoperative complications. Subsequently, considering female ACL injuries as a separate entity to males is important, as this will advance our understanding of sex differences and, consequently, outcomes for this patient group.

We acknowledge that our decision to focus solely on female athletes may be seen as a limitation, as there is a similar dearth of articles that focus on male athletes. Though many of the larger studies on outcomes after ACLR feature both sexes, the female sex is often less represented as a percentage of the study population, and is consistently found to be a predictor of worse outcomes.41-45 We hope to highlight the lack of female athlete-specific outcome studies, not to suggest that they are more important than outcome studies in male athletes, but rather to further investigate a population that historically has worse outcomes after ACLR in an attempt to understand why.

Additionally, this scoping review employed rigorous methodology in order to map the data, identify gaps in the literature, and highlight controversies regarding this issue in primary ACLR surgery for female-specific literature. This is a novel study providing a broad and contextual overview of the literature regardless of the quality, encompassing studies since inception. While the review is not designed to analyze data subsets statistically, it is clear that there would be risk of a lack of granularity in reporting variables and outcomes to enable a robust systematic review and meta-analysis. There would also be a significant risk of data heterogeneity. For the purposes of this scoping review, ‘female’ was defined as sex assigned at birth. While the authors did not encounter any studies which highlighted any transgender patients, or those who had undergone hormonal treatment/sex reassignment surgery, it is important to note that this may need to be a consideration in the future.

Future research priorities

Given the main message of this scoping review with regard to lack of standardized reporting, there is clearly a need for standardization of reporting criteria for female-specific studies looking at primary ligament injuries around the knee. This would enable greater comparison of data in the future, and allow more robust conclusions to be drawn from any meta-analysis. Relevant data should be standard in ACLR outcome literature, including age, height/weight/BMI, and notch width (demographic data), time from injury to operation, graft type, graft size, and meniscal treatment (operative criteria), IKDC and KOOS (patient-reported outcome measures), re-rupture rate, time to failure, and return to sport rates (clinical outcomes). The authors of this paper suggest the need for further discussion regarding the most relevant reporting criteria through an international consensus statement of experts in order to accurately assess the future validity of studies. There is a clear need for a drive for female-specific studies to be conducted in the future, in order to truly assess the impact this injury has on this sub-group of patients and their outcomes, as current literature is heavily biased towards males.46

In conclusion, this scoping review identified 16 studies which analyzed specific outcomes in female athletes after primary ACLR. There is a significant lack of studies in the literature reporting on female-specific outcomes, and in those studies eligible for the scoping review, there was a significant lack of standardization of variable and outcome reporting. Further research is required to develop standardized reporting criteria in order to accurately reflect the outcomes of primary ACLR in female athletes.

Take home message

- Anterior cruciate ligament outcomes research that focuses on female athletes lacks standardized outcome variables.

- By highlighting the gaps and inconsistencies in data reporting, we hope to work towards developing a more unified approach to outcomes reporting in this population.

Author contributions

B. Gibbs: Conceptualization, Data curation, Methodology, Writing – original draft, Writing – review & editing

A. Eleftheriadou: Formal analysis, Writing – original draft, Writing – review & editing

J. Saleet: Data curation, Methodology

M. J. Tanaka: Conceptualization, Writing – original draft, Writing – review & editing

X. Li: Conceptualization, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

K. Al-Hourani: Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Supervision, Writing – original draft, Writing – review & editing

Funding statement

The author(s) received no financial or material support for the research, authorship, and/or publication of this article.

ICMJE COI statement

K. Al-Hourani reports consulting fees from Joint Operations, and support for attending meetings and/or travel from Joint Operations and AAOS/AOSSM, unrelated to this study. X. Li reports consulting fees from FH Ortho, unrelated to this study. M. J. Tanaka reports grants or contracts from AANA, FujiFilm Corporation, and Voice in Sports, and consulting fees from Arthrex, Johnson & Johnson, Vericel, and Verywell Health, all of which are unrelated to this study. M. J. Tanaka is also on the editorial board of Arthroscopy Journal, the AO Sports Medicine Steering Board, is Editor in Chief of the Journal of Women’s Sports Medicine, Associate Editor of AJSM, and CME Associate Editor of JBJS.

Data sharing

The data that support the findings for this study are available to other researchers from the corresponding author upon reasonable request.

Open access funding

The open access fee for this article was self-funded.

© 2026 Gibbs et al. This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives (CC BY-NC-ND 4.0) licence, which permits the copying and redistribution of the work only, and provided the original author and source are credited. See https://creativecommons.org/licenses/by-nc-nd/4.0/

Data Availability

The data that support the findings for this study are available to other researchers from the corresponding author upon reasonable request.

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Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Data Availability Statement

The data that support the findings for this study are available to other researchers from the corresponding author upon reasonable request.


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