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Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1972 Oct;36(4):339–344.

The ERA Strain of Rabies Vaccine

K F Lawson, J F Crawley
PMCID: PMC1319696  PMID: 4263912

Abstract

An antigenic extinction trial in cats showed that the ERA rabies vaccine had superior antigenic properties over Flury H.E.P. C.E.O. and killed tissue culture rabies vaccine.

Dogs and cats on a duration of immunity study of ERA rabies vaccine were challenged with fox salivary gland “street” rabies virus. The results of this challenge show a duration of immunity of five years in dogs and four years in cats.

Vaccination of dams in late pregnancy with ERA rabies vaccine resulted in transference of maternal antibody to the newborn, in both cattle and dogs. This maternally derived antibody interfered with the successful active immunization of the young calf. Calves free of antibodies for rabies could be successfully vaccinated as early as 17 days of age and were able to withstand a challenge with virulent “street” rabies virus two years later.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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Articles from Canadian Journal of Comparative Medicine are provided here courtesy of Canadian Veterinary Medical Association

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