Skip to main content
Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1972 Oct;36(4):398–402.

Vitamin E, Selenium and Methionine Supplementation of Dystrophogenic Diets for Pigs

B A Sharp 1,2, L G Young 1,2, A A van Dreumel 1,2
PMCID: PMC1319707  PMID: 4263922

Abstract

Forty-eight weanling S.P.F. Yorshire pigs were used to study the influence of supplemental vitamin E (25 IU per kg of diet) selenium (0.5 ppm in diet) and methionine (0.1% in diet) on the incidence of hepatosis dietetica and mulberry heart disease when fed a torula yeast-corn diet. Vitamin E and/or selenium increased pig survival. Supplemental selenium resulted in increased liver selenium concentrations. No hepatosis dietetica was observed in any of the pigs. The addition of vitamin E and/or selenium at the levels used did not reduce the frequency of myocardial lesions; however, they prevented skeletal muscular dystrophy and exudative diathesis. The myocardial lesions were less severe in supplemented pigs compared with unsupplemented controls.

Full text

PDF
398

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Baustad B., Nafstad I. Gastric ulcers in swine. 4. Effects of dietary particle size and crude fiber contents on ulceration. Pathol Vet. 1969;6(6):546–556. doi: 10.1177/030098586900600608. [DOI] [PubMed] [Google Scholar]
  2. CURTIN T. M., GOETSCH G. D., HOLLANDBECK R. CLINICAL AND PATHOLOGIC CHARACTERIZATION OF ESOPHAGOGASTRIC ULCERS IN SWINE. J Am Vet Med Assoc. 1963 Oct 15;143:854–860. [PubMed] [Google Scholar]
  3. Cuperlović M., Stosić D. Some effects of protein deficiency in young growing pigs. II. Blood plasma free amino acids. Acta Vet Scand. 1970;11(1):1–15. doi: 10.1186/BF03547999. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Michel R. L., Whitehair C. K., Keahey K. K. Dietary hepatic necrosis associated with selenium-vitamin E deficiency in swine. J Am Vet Med Assoc. 1969 Jul 1;155(1):50–59. [PubMed] [Google Scholar]
  5. Reid I. M., Barnes R. H., Pond W. G., Krook L. Methionine-responsive liver damage in young pigs fed a diet low in protien and vitamin E. J Nutr. 1968 Aug;95(4):499–508. doi: 10.1093/jn/95.4.499. [DOI] [PubMed] [Google Scholar]
  6. Sharp B. A., Young L. G., Van Dreumel A. A. Dietary induction of mulberry heart disease and hepatosis dietetica in pigs. I. Nutritional aspects. Can J Comp Med. 1972 Oct;36(4):371–376. [PMC free article] [PubMed] [Google Scholar]

Articles from Canadian Journal of Comparative Medicine are provided here courtesy of Canadian Veterinary Medical Association

RESOURCES