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Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1981 Jan;45(1):82–86.

Failure to Detect Soluble Tumor Associated Antigen by Radioimmunoassay in Bovine Lymphoma

RM Jacobs, VEO Valli, BN Wilkie
PMCID: PMC1320125  PMID: 7272845

Abstract

The detection of circulating soluble tumor-associated antigen by radioimmunoassay was attempted in cows with lymphoma. The assay system did detect PAGE-purified tumor-associated antigen but did not detect immunoreactive substances in the sera of 20 affected animals and 20 normal cattle. Similarly, ultrafiltration of low pH-dissociated serum to separate immune complexes did not aid in the detection of antigen.

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Selected References

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