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Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1982 Jul;46(3):264–266.

Immune Responses of Dairy Cattle to Parainfluenza-3 Virus in Intranasal Infectious Bovine Rhinotracheitis-Parainfluenza-3 Virus Vaccines

AL Burroughs, JL Morrill, JL Bostwick, RK Ridley, HC Fryer
PMCID: PMC1320320  PMID: 6290012

Abstract

Two hundred and fifty dairy heifers were vaccinated at three to six months of age with an intranasal infectious bovine rhinotracheitis-parainfluenza-3 vaccine. Eighteen additional heifers were tested prior to vaccination and again three to four weeks after vaccination. Neither cell-mediated nor humoral immunity was significantly raised to parainfluenza-3 virus in either group of cattle.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fukumi H. Meaning of circulating antibody titers in the infections of parainfluenza 3 virus and RS virus. Dev Biol Stand. 1975;28:159–166. [PubMed] [Google Scholar]
  2. Gerber J. D., Brown A. L. Effect of development and aging on the response of canine lymphocytes to phytohemagglutinin. Infect Immun. 1974 Oct;10(4):695–699. doi: 10.1128/iai.10.4.695-699.1974. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. HAMPARIAN V. V., WASHKO F. V., KETLER A., HILLEMAN M. R. Laboratory and field investigations of bovine Myxovirus parainfluenza 3 virus and vaccine. III. Evaluation of an SF-4 (shipping fever) virus vaccine in cattle. J Immunol. 1961 Aug;87:139–146. [PubMed] [Google Scholar]
  4. HOERLEIN A. B., MANSFIELD M. E., ABINANTI F. R., HUEBNER R. J. Studies of shipping fever of cattle. I. Para-influenza 3 virus antibodies in feeder calves. J Am Vet Med Assoc. 1959 Aug 1;135(3):153–160. [PubMed] [Google Scholar]
  5. Johnson K., Morein B. In vitro stimulation of bovine circulating lymphocytes by parainfluenza type 3 virus. Res Vet Sci. 1977 Jan;22(1):83–85. [PubMed] [Google Scholar]
  6. Moreno-López J. Cell-mediated immunity to parainfluenza-3 (PIV-3) in cattle. Evaluation of in vivo and in vitro tests. Zentralbl Veterinarmed B. 1977 Mar;24(3):231–240. doi: 10.1111/j.1439-0450.1977.tb00993.x. [DOI] [PubMed] [Google Scholar]
  7. Muscoplat C. C., Chen A. W., Johnson D. W., Alhaji I. In vitro stimulation of bovine peripheral blood lymphocytes: standardization and kinetics of the response. Am J Vet Res. 1974 Dec;35(12):1557–1561. [PubMed] [Google Scholar]
  8. Naylor P. F., Little T. W. A simple method for isolating leucocytes from bovine blood and their separation into lymphocyte and granulocyte fractions. Res Vet Sci. 1975 May;18(3):336–337. [PubMed] [Google Scholar]
  9. Park B. H., Good R. A. A new micromethod for evaluating lymphocyte responses to phytohemagglutinin: quantitative analysis of the function of thymus-dependent cells. Proc Natl Acad Sci U S A. 1972 Feb;69(2):371–373. doi: 10.1073/pnas.69.2.371. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Smith W. D., Dawson A. M., Wells P. W., Burrells C. Immunoglobulins in the serum and nasal secretions of lambs following vaccination and aerosol challenge with parainfluenza 3 virus. Res Vet Sci. 1976 Nov;21(3):341–348. [PubMed] [Google Scholar]

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