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[Preprint]. 2026 May 28:2026.05.26.26354165. [Version 1] doi: 10.64898/2026.05.26.26354165

Grounding Language Models in Behavioral Science to Scale Physical Activity Interventions for Hispanic/Latinx Populations

Sriya Mantena, Anders Johnson, Narayan Schuetz, Alexander Tolas, Samuel Montalvo, Juan Delgado-SanMartin, Mariana Ramirez-Posada, Lina Du, Sophia Zhang, Andy Duc Huynh, Marily Oppezzo, Abby C King, Paul Schmiedmayer, Allan Lawrie, Fatima Rodriguez, Euan A Ashley, Daniel Seung Kim
PMCID: PMC13232421  PMID: 42245042

ABSTRACT

Objective

Hispanic/Latinx populations in the U.S. experience higher rates of chronic disease linked to physical inactivity, yet digital health interventions remain largely inaccessible to more than 16 million Hispanic/Latinx adults with limited English proficiency. While large language models (LLMs) offer scalable personalization, their use in non-English behavioral coaching is unexplored. This study introduces MHC-Coach-ES, a Spanish-language LLM fine-tuned on the Transtheoretical Model (TTM) of behavior change.

Materials and Methods

We fine-tuned Llama 3-70B-Instruct using a two-stage pipeline. First, the model was adapted to Spanish health and motivational language using a 2.21-million-token corpus. Second, it was instruction-tuned on 3,268 translated human written messages to align the model with the Transtheoretical Model (TTM) of Behavioral Change. We compared MHC-Coach-ES with Llama 3-70B-Instruct and translated human-expert messages using a forced-choice preference survey (N = 77) and blinded expert review (N = 2).

Results

Spanish-speaking participants significantly preferred MHC-Coach-ES messages over translated human-expert messages (81% preference, P <0.001). Linguistic analysis showed that MHC-Coach-ES produced more temporally anchored messages than the base model (65% vs. 20%), while maintaining readability. In blinded evaluation, clinical experts rated MHC-Coach-ES higher for alignment with Transtheoretical Model stages than human-expert messages (4.83 vs. 4.38 out of 5). The base model also outperformed translated expert messages across preference and expert ratings.

Conclusions

Generative AI can operationalize behavioral science frameworks in Spanish, offering a scalable approach to reducing health disparities. The strong performance of both MHC-Coach-ES and the base model highlights the promise of generative and personalized approaches over translation-based localization for theory-driven behavioral interventions.

Full Text Availability

The license terms selected by the author(s) for this preprint version do not permit archiving in PMC. The full text is available from the preprint server.


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