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. 2026 Jun 5;21(6):e0349413. doi: 10.1371/journal.pone.0349413

Gender differences in provider practice characteristics and medicare payment & services among diagnostic radiologists

Ajay Malhotra 1,*, Chris J Lee 1, Mihir Khunte 1, Raj Moily 1, Dheeman Futela 1, Seyedmehdi Payabvash 2, David Seidenwurm 3, Dheeraj Gandhi 4
Editor: Lorenzo Faggioni5
PMCID: PMC13240891  PMID: 42247376

Abstract

Background

Gender-based differences in representation, practice settings, sub-specialty, billings, and payments among radiologists are poorly understood.

Purpose

To compare representation, scope of practice, productivity, and Medicare payments between female and male diagnostic radiologists.

Methods and materials

This cross-sectional (2017–2021) retrospective study examined the CMS Medicare Fee-for-Service Provider Utilization and Payment Database for payments to male and female diagnostic radiologists. The study practice setting, volume of services provided, number of unique beneficiaries served and financial data. Descriptive statistics were reported as mean with standard error (SE) for financial variables and median with interquartile range (IQR) for non-financial variables.

Results

Between 2017–2021 data, a total of 33,029 diagnostic radiologists provided services to Medicare fee-for-service beneficiaries, of whom 8,217 (24.9%) were female. Female radiologists were disproportionately in academic versus non-academic radiology (34.2% vs 22.6%); practicing in urban versus rural areas (26.3% vs 17.0%); in larger practices (30.1% in practices with ≥100 radiologists vs 17.5% in practices with 1–9 radiologists); and in certain subspecialties (breast imaging- 64.9%). On average, female radiologists received 86% of the total Medicare payments received by male radiologists (mean [SE], $301,931 [$1810] vs $352,604 [$1,164]; p < .001). Female radiologists billed fewer median total services (6,660 vs 9,859; p < .001), served fewer beneficiaries (5,441 vs 7,678; p < .001), and billed fewer unique codes (20 vs 39; p < .001). Overall, female radiologists’ average (SE) payment per service was 18% higher than males [$36.26 (0.13) versus $30.71 (0.06), respectively, but were similar within each subspecialty.

Conclusion

Female radiologists are disproportionately in academic, urban, and large practices and work as subspecialists. Further, while total Medicare payments received by females were less than males, average payments per service were higher for females overall, but comparable by sex in the same subspecialty.

Introduction

Female representation in the radiology workforce is less than for males and has only marginally increased in the last decade [1–3]. Financial compensation is important for physician recruitment and retention, and recent studies have shown differences in salaries between females and males in academic radiology [4–7]. However, the gender-based differences in representation, practice settings, sub-specialty, billings, and payments in radiology practice remain poorly understood.

Since 2010, the Centers for Medicare & Medicaid Services (CMS) has published data on physician demographics and reimbursements that is publicly available [8]. These data allow for a thorough analysis of billing and payments for physicians in different practice settings throughout the United States. Previous studies using these data have shown the existence of a gender pay gap for physicians overall and in specialties such as, but not limited to, radiation oncology, ophthalmology, otolaryngologists, cardiology, and neurosurgery [9–13]. Female physicians are estimated to earn approximately $2 million less than their male counterparts over a 40-year career even when controlling for the number of hours worked, clinical volume, and specialty [14]. This trend has been demonstrated in studies focusing on different physician subpopulations across different specialties, different practice types, as well as geographic locations [15]. However, these differences for female and male U.S. radiologists have not been well described.

As pay differences between genders are associated with various factors, the objective of this study is to assess any gender-based differences in radiologists’ practice volume (number of charged services and beneficiaries), breadth of practice (number of unique Medicare billing codes), charges and payments (the mean dollar amount Medicare was charged and the payment received from Medicare) by analyzing the publicly available CMS data over a 5-year period (2017–2021).

Methods

Data

This cross-sectional retrospective study examined the CMS Medicare Fee-for-Service Provider Utilization and Payment Database for payments to diagnostic radiologists from January 1, 2017, to December 31, 2021 [8]. As the data are publicly available, the study was not subject to institutional review board review oversight. The data was accessed in October 2024. Physician-level payment information was obtained for services performed and their corresponding Medicare reimbursements from 2017 to 2021. Each row of the dataset contains a unique combination of Current Procedural Terminology (CPT) or Healthcare Common Procedure Coding System (HCPCS) codes and National Provider Identifier (NPI) allowing identification of services provided by individual physicians. These data were supplemented with physician demographic information, practice location, number of services rendered, number of beneficiaries served, and Medicare payments and charges. Information on the number of years in practice was derived from the physician’s medical school graduation year obtained from the publicly available National Plan & Provider Enumeration System’s database and linked using the clinician’s NPI [16]. The Neiman Imaging Types of Service (NITOS) database was used to categorize CPT/HCPCS codes based on characteristics such as invasiveness, modality, body region, and focus [17]. Specifically, NITOS was used to categorize the modality and body region of the imaging for each service rendered by radiologists. The unit of analysis was at the individual physician level. Physicians were included in the study if their self-reported specialty code for Medicare was diagnostic radiology, and they practiced in the 50 states or District of Columbia.

Variables

The primary variable of interest was gender, which was a self-reported binary variable obtained from the National Plan & Provider Enumeration System’s database. Diagnostic radiologists were classified by gender to examine differences in clinical practice characteristics and Medicare-related financial outcomes. First, clinical practice volume was assessed by the total number of services provided and the number of unique beneficiaries served. To characterize the breadth of practice for each physician, we identified the number of unique CPT/HCPCS codes billed. Financial variables included were charges submitted to Medicare and payments received from Medicare. All financial data were adjusted for inflation to 2021 values using the Consumer Price Index [18].

Radiologists were categorized as either generalists or in one of five subspecialties: abdominal, breast, cardiothoracic, musculoskeletal, and neuroradiology. Subspecialty identification was based on work relative value units (wRVUs) linked to claims in the CMS “Medicare Physician & Other Practitioners – by Provider and Service” database. Each claim code was categorized into one of the five subspecialties using imaging modality and body region according to the NITOS system. This was necessary because CMS specialty data simply identify diagnostic radiologists. They do not indicate the radiologic subspecialty. Each radiologist was identified as practicing within a certain subspecialty if more than 50% of their total wRVUs were in that subspecialty. Those not meeting the 50% threshold for a subspecialty were categorized as generalists. This threshold and the NITOS-based classification system have been validated in both the academic and private practice settings in previous studies and sensitivity analyses as a robust approach for subspecialty identification [19–21]. Radiologists subspecializing in nuclear medicine and vascular & interventional radiology were excluded from the dataset to focus exclusively on diagnostic radiologists. Academic and non-academic status was determined using data from the Harvey L. Neiman Health Policy Institute Academic Radiology Practices categorized the academic status of practices associated with radiologists in CMS files [22]. Urban and rural practice locations were determined using Rural-Urban Commuting Area (RUCA) codes based on the practice ZIP code [23]. Practice size was defined as the number of physicians working in the same group, which is available within the CMS data.

Statistical analyses

All analyses were conducted with R version 4.4.2 (R Foundation for Statistical Computing, Vienna, Austria). All statistical tests were two-tailed, with an alpha level of 0.05 used to determine significance. Trends in payment amounts over time were determined with a time-series analysis with a two-tailed alpha level (α = 0.05). Descriptive statistics were reported as mean with standard error (SE) for parametric data (e.g., charges, payments) and median with interquartile range (IQR) for nonparametric data (e.g., number of services, beneficiaries, and codes). Independent t-test were used to compare mean values while the Mann-Whitney U test (also known as the Wilcoxon t-test) was used to compare medians.

Results

The 2017–2021 data included a total of 33,029 diagnostic radiologists who provided services to Medicare beneficiaries, of whom 8,217 (24.9%) were female and 24,812 (75.1%) were male. The number of female radiologists increased from 6,747 in 2017–7,321 in 2021 (p < .001), and the number of male radiologists increased from 21,033 in 2017–21,610 in 2021 (p = .003). Hence, over the 2017–2021 period, the female representation increased 1 percentage point from 24.3% to 25.3% of all radiologists (Table 1).

Table 1. Demographics and percentage representation of women in radiology.

Percent female % (No./Total no.)
2017 2021 All years
Overall 24.3 (6,747/27,780) 25.3 (7,321/28,931) 24.9 (8,217/33,029)
Academic status
 Academic 34.5 (1,619/4,692) 34.3 (1,983/5,774) 34.2 (221/948)
 Nonacademic 22.2 (3,380/15,232) 22.6 (3,975/17,619) 22.6 (176/1,131)
Practice rurality
 Urban 25.8 (5,146/19,909) 26.3 (6,194/23,559) 26.3 (425/2,199)
 Rural 16.7 (476/2,843) 17.0 (547/3,216) 17.0 (32/182)
Years in practice
  < 10 24.9 (101/405) 25.6 (934/3,651) 25.5 (59/365)
 10-24 27.5 (3,242/11,804) 28.0 (3,505/12,535) 28.0 (260/1,239)
  ≥ 25 22.0 (2,420/10,997) 22.2 (2,467/11,126) 22.2 (147/806)
Group practice size
  < 10 members 16.9 (275/1,625) 17.3 (312/1,799) 17.5 (4/36)
 10–49 member 19.5 (1,246/6,380) 19.7 (1,450/7,344) 19.8 (51/284)
 50–99 members 22.9 (813/3,552) 23.3 (981/4,207) 23.1 (60/425)
  ≥ 100 members 29.7 (3,363/11,317) 30.1 (4,100/13,630) 30.1 (352/1,663)
Geographic region
 Midwest 22.0 (1,355/6,167) 23.2 (1,585/6,830) 22.3 (108/608)
 Northeast 30.9 (1,952/6,309) 32.0 (2,049/6,399) 31.6 (164/688)
 South 21.7 (2,034/9,374) 22.8 (2,209/9,695) 22.4 (149/896)
 West 23.5 (1,350/5,742) 24.4 (1,420/5,811) 24.2 (105/509)
Subspecialty
 Abdominal 29.7 (969/3,265) 29.6 (1,077/3,634) 29.4 (1,203/4,088)
 Breast 64.2 (2,345/3,654) 67.9 (2,498/3,681) 64.9 (2,749/4,236)
 Cardiothoracic 28.8 (373/1,295) 31.1 (442/1,421) 29.7 (571/1,923)
 Musculoskeletal 20.9 (339/1,621) 21.5 (373/1,734) 21.7 (430/1,983)
 Neuroradiology 19.6 (451/2,298) 20.3 (534/2,631) 20.6 (603/2,933)
 Generalists 14.5 (2,270/15,647) 15.1 (2,397/15,830) 14.9 (2,661/17,866)

Relative to their overall mean representation among diagnostic radiologists (24.9%), 34.2% of academic radiologists were female, compared to 22.6% in non-academic settings; The proportion of female radiologists also varied by practice location and size: 26.3% practiced in urban areas versus 17.0% in rural areas, and 30.1% were in large practices (≥100 radiologists) compared to 17.5% in small practices (1–9 radiologists). Subspecialty distribution showed the highest female representation particularly in breast imaging, where 64.9% of practitioners were female, followed by cardiothoracic (29.7%) and abdominal imaging (29.4%), while lower proportions were observed in neuroradiology (21.7%), musculoskeletal imaging (14.9%), and general radiology (20.6%) (Table 1). By years of practice, female radiologists had disproportionately higher representation with 10–24 years (28.0%) or 1–9 years (25.5%) versus those with ≥25 years of practice (22.2%). The Northeast region had the highest share of female radiologists (31.6%). Geographically, there was variation between states. The highest female representation was seen in the Northeast, near Washington D.C., California, and Washington state (Fig 1).

Fig 1. Heat map of female radiologist representation by state.

Fig 1

On average, female radiologists submitted charges annually that were 76% of that submitted by males (mean [SE], $1,472,306 [$9,066] vs $1,928,044 [$6,363]; p < .001) and were paid by Medicare 86% of what males were (mean [SE], $301,931 [$1810] vs $352,604 [$1,164]; p < .001). The total number of annual services that female billed were 68% of the services billed by males (6,660 [IQR, 3,168–11,990] vs 9,859 [IQR, 4,938–16,575]; p < .001). Females annually served 71% as many beneficiaries (5,441 [IQR, 2,694–9,159] vs 7,678 [IQR, 3,958–12,231]; p < .001), and billed 51% as many unique codes (20 [IQR, 10–37] vs 39 [IQR, 21–55]; p < .001) (Table 2). Hence, normalizing payments based on services rendered, female radiologists received an average (SE) payment of $36.26 (0.13) that is 18% higher than the $30.71 (0.06) average payment per service rendered by male radiologists (Table 3).

Table 2. Medicare annual charges, payments, and practice volume metrics by gender.

Females Males P-value
Charges and payments* Mean (SE)
 Total submitted charges $1,472,306 (9,066) $1,928,044 (6,363) <.001
 Total payments $301,931 (1,810) $352,604 (1,164) <.001
 Payment-to-charge ratio 0.23 (0.0006) 0.21 (0.0003) <.001
 Payment-per-Service $36 (0.13) $31 (0.06) <.001
Practice volume Median (IQR)
 Total services 6,660 (3,168−11,990) 9,859 (4,938−16,575) <.001
 Total beneficiaries 5,441 (2,694−9,159) 7,678 (3,958−12,231) <.001
 Unique codes 20 (10-37) 39 (21-55) <.001

*Adjusted by Consumer Product Index (CPI).

Table 3. Medicare payments by demographic characteristic and gender.

Medicare payments, services, and payment per service by gender
Females Males Female-to-male ratio
Average payments per radiologist Average services per radiologist Payment per service Average payments per radiologist Average services per radiologist Payment per service Average payments per radiologist Average services per radiologist Payment

per service
Overall $301,931 6600 $36.26 $352,604 9859 $30.71 0.86 0.67 1.18
Academic status
 Academic $214,777 7521 $32.99 $241,078 9553 $30.96 0.89 0.79 1.07
 Nonacademic $321,905 9725 $36.50 $369,876 13483 $29.68 0.87 0.72 1.23
Practice rurality
 Urban $293,304 9068 $36.14 $344,718 12517 $30.90 0.85 0.72 1.17
 Rural $285,182 10483 $28.90 $366,273 14243 $26.73 0.78 0.74 1.08
Years in practice
  < 10 $162,896 5543 $30.81 $181,277 6970 $27.07 0.9 0.8 1.14
 10-24 $297,113 9316 $36.01 $361,802 13257 $30.56 0.82 0.7 1.18
  ≥ 25 $333,339 10141 $37.70 $380,922 13827 $31.54 0.88 0.73 1.2
Group practice size
  < 10 members $347,853 9432 $46.93 $437,750 14613 $34.83 0.79 0.65 1.35
 10–49 member $356,377 10890 $35.71 $395,448 14493 $29.49 0.9 0.75 1.21
 50–99 memers $347,673 10887 $35.51 $373,203 14110 $29.01 0.93 0.77 1.22
  ≥ 100 members $250,529 8056 $34.85 $287,700 10767 $30.37 0.87 0.75 1.15
Geographic region
 Midwest $245,397 8837 $30.56 $279,083 10774 $28.38 0.88 0.82 1.08
 Northeast $281,299 8261 $39.56 $341,685 11436 $34.79 0.82 0.72 1.14
 South $305,434 9676 $35.40 $356,204 13537 $29.47 0.86 0.71 1.2
 West $270,707 7790 $36.76 $310,045 11325 $30.50 0.87 0.69 1.21
Subspecialty
 Abdominal $256,901 9002 $34.23 $339,337 12421 $33.25 0.76 0.72 1.03
 Breast $348,755 7289 $46.62 $409,468 8815 $46.41 0.85 0.83 1
 Cardiothoracic $142,146 6021 $16.74 $153,356 7185 $16.03 0.93 0.84 1.04
 Musculoskeletal $208,936 7441 $36.00 $277,424 8861 $38.40 0.75 0.84 0.94
 Neuroradiology $237,174 6523 $39.91 $310,432 8631 $39.91 0.76 0.76 1
 Generalists $326,939 11130 $29.07 $375,572 13391 $27.56 0.87 0.83 1.05

Table 3 shows similar patterns by the characteristics of the radiologists. Female academic radiologists’ payments from Medicare were 89% of academic males ($214,777 vs $241 078). The results show similar patterns for urban/rural, years of practice, practice size, region, and subspecialty. For example, females received lower total payments than males for every subspecialty. The smallest female-to-male payment ratio was 75% for musculoskeletal imaging ($208,936 for females vs $277,424 for males; p < 0.001) and the largest ratio was 93% for cardiothoracic imaging ($153,356 vs $142,146; p = 0.016). Normalizing these payments based on services rendered, Table 3 also shows the average payments per service for female and male radiologists by their characteristics. Female compared with male average payments per service are 7% higher for academic radiologists ($32.99 vs $30.96) and 23% higher for non-academic radiologists. Likewise, average payments per service are higher for female than male radiologists in both urban (17%) and rural areas (8%) and regardless of years of practice, practice size, or region of the county. In contrast, there is generally parity between female and male radiologists in payments per service for those in the same subspecialty, ranging from 6% less for musculoskeletal to 5% more for generalists.

To better understand whether the observed gender differences persisted after accounting for practice and workload variables, we performed a multivariable linear regression analysis. The model adjusted for the number of services provided, number of beneficiaries, rural versus urban practice location, years in practice, group size, geographic region, and subspecialty. After adjustment, female radiologists remained significantly associated with lower total annual submitted charges (p = 0.004). However, they were also associated with higher total Medicare payments, independent of clinical volume and practice characteristics (p = 0.001). These findings suggest that female radiologists, on average, may provide a mix of services that are reimbursed at higher rates, potentially reflecting differences in procedural focus, coding strategies, or patient complexity not captured by raw service counts.

For the entire 2017–2021 period, Medicare payments to female radiologists were 86% that of males. However, over this period, this ratio trended upward from 83% in 2017 to 89% in 2021 (Fig 2). At the same time, the ratio of female-to-male services rendered also increased from 64% in 2017 to 72% in 2021, and the ratio of female-to-male payments per service rendered was 115% in 2017 and 116% in 2021. The combination of the constant parity per service and increasing number of services are associated with the improving aggregate Medicare payment parity between female and male radiologists.

Fig 2. Change over time in median number of services, mean payment per service and mean total payment to females compared to male radiologists.

Fig 2

Discussion

This retrospective analysis of gender-based differences among diagnostic radiologists found that relative to the one-quarter of radiologists who are female, female radiologists are disproportionately in academic settings, urban, and large practices and work as subspecialists particularly in breast, cardiothoracic, and abdominal imaging. Further, total Medicare payments received by females are less than males as are the services they rendered to Medicare patients, but on a per service basis, female radiologists’ Medicare payments per services were 18% more than males.

We found that female radiologists were disproportionately in academic radiology at 34.2%. This is consistent with previous studies of academic radiologists published in 2016 and 2017, which ranged from 29–34% [24,25]. The share of females in academic radiology has risen over time from 11.5% in 1978 to 28.1% in 2013 [26]. We found that by years of practice, females represented 25.5%, 28.0%, and 22.2% of radiologists with 1–9, 10–24 and ≥25 years of practice, respectively. While these shares indicate some increase in female representation over time because the share was lowest for those with ≥25 years of practice, we did not observe those with 1–9 years of practice having the highest female representation. Hence, if such a trend continues, female representation in radiology may plateau.

We found that female radiologists were disproportionately subspecialized, most commonly working in breast, cardiothoracic, and abdominal imaging. This is consistent with a study that found female radiologists were more likely to only practice in one specialty [27]. Interestingly, while we found that females were the least represented in musculoskeletal imaging, this likely does not translate to females being less represented in academic musculoskeletal radiology as a previous study found that 30.7% of these faculty were females [28]. We found that females were more likely in urban areas, which is consistent with the prior study [29]. This combined with females’ higher propensity to be employees and disproportionate representation in academic practices is consistent with our finding that females are disproportionately in large practices [29].

An array of similar studies found the existence of a gender-based payment difference in other specialties, such as but not limited to radiation oncology, ophthalmology, otolaryngologists, cardiology, and neurosurgery [9–13]. Considering only total Medicare payments, we found that female radiologists’ payments from Medicare were 86% that of males. While some studies have found a gender pay difference for radiologists, our results are only representative of payments from Medicare not all sources. For example, a 2021 study found the female physicians’ income was 12% less than males after adjusting for covariates. [14] This same study found that females Medicare reimbursement was 52% less than males [14]. This may suggest that female radiologists may derive a relatively larger proportion of their income from non-Medicare sources such as commercial insurance or institutional compensation models, though this remains a hypothesis and was not directly tested in our analysis. Consequently, these findings represent differences in Medicare FFS reimbursement and should not be interpreted as a measure of total physician compensation.

Furthermore, our multivariable, regression-adjusted results offer deeper insight into the observed gender-based differences in radiology practice. Even after controlling for service volume, practice setting, years of experience, and subspecialty, female radiologists continued to submit lower annual charges yet received higher Medicare payments. This divergence indicates that compensation differences are not solely attributable to differences in workload or access to billing opportunities, but may reflect underlying variations in clinical roles, coding patterns, or the relative value of services performed. Importantly, payment per service is influenced by differences in subspecialty, modality mix, and geographic adjustment factors. The higher adjusted payments observed among female radiologists may suggest a focus on more complex or evaluative services that yield greater reimbursement per encounter. Taken together, these findings underscore the importance of examining not only how much radiologists work, but also the nature and structure of the work they perform, when evaluating gender-based disparities in compensation. Surveys have also found that female radiologists earned less than males with varying estimates of differences with one study finding a 23% difference [29,30]. A recent study of academic U.S. radiology faculty using AAMC data found that female radiologist’s earnings were 3–6% lower than their male counterparts [4,7]. While these studies have all adjusted for covariates, the greatest differences are derived from surveys of radiologists generally, with smaller differences from surveys of like radiologists, such as surveys of only academic radiologists, and no difference for the study of reported salaries of all academic radiologists of the institutions included in the study. This may suggest that covariates in some studies insufficiently capture differences across radiologists as estimated earnings differences decrease or become insignificant as the samples because more alike. This possibility is consistent with our finding that once Medicare payments were normalized by differences in the number of services rendered, females were paid 18% more per service. Concluding that females are paid 18% more than males is misleading because Medicare payments are set by the Medicare Physician Fee Schedule. Hence, differences in payments per service can only stem from differences in the mix and count of specific services rendered, the share of services that include the technical component in addition to the professional component, and reimbursement differences associated with the Geographic Practice Cost Index. Such differences would be associated with how female and male radiologists sort themselves across practice type, location, and size, but principally by subspecialty. We found that for radiologists in the same subspecialty, there was generally gender parity in payments per service, which is logical given the Medicare Physician Fee Schedule.

Limitations

Our study has limitations. First, the data are limited to Medicare billing data from 2017–2021, which excludes data for physicians who do not accept Medicare; however, only fewer than 0.1% of radiologists do not accept Medicare [31]. The uniformity of the Medicare data was crucial to this study’s objective to examine payment trends among diagnostic radiologists submitting Medicare fee-for-service claims. Second, since services provided to patients are covered by other payors (i.e., commercial insurers, Medicaid, and Medicare Advantage), it is possible that characterization of radiologists’ subspecialties based on Medicare fee-for-service data alone, may mischaracterize the subspecialty in some instances. Further, we used a previously established method (using wRVUs and NITOS codes) to determine radiologists’ subspecialties based on services rendered, not fellowship training [19–21]. Lastly, while this study focused on Medicare payments to physicians, factors including practice type (private vs employed) and hospital policies may differentially affect reimbursement and the amount of actual dollars that end up in doctors’ take-home salaries and compensation. Additionally, it is important to note that data on working hours or full-time equivalent (FTE) status were not available and could influence payment differences. Furthermore, gender was captured as a self-reported binary variable within the CMS/NPPES datasets; consequently, this study is limited by the lack of representation for non-binary gender identities.

In conclusion, we found that relative to the one-quarter of radiologists overall who are female, female radiologists are disproportionately in academic, urban, and large practices and work as subspecialists particularly in breast, cardiothoracic, and abdominal imaging. Further, while total Medicare payments received by females are less than males, payments per service rendered were higher for female radiologists than for males overall, but were comparable between genders for the same subspecialty.

Key points

  1. Female radiologists are better represented in academic radiology, practice in urban areas, in larger practices and in certain subspecialties.

  2. On average, female radiologists submitted charges that were 76% of that submitted by males and were paid by Medicare 86% of what male radiologists were paid.

  3. There was generally parity between female and male radiologists in payments per service for those in the same subspecialty

Data Availability

DATA AVAILABILITY STATEMENT This study used publicly available data from the CMS Medicare Physician & Other Practitioners dataset (2017–2021). The data are accessible at: https://data.cms.gov/provider-summary-by-type-of-service/medicare-physician-other-practitioners-by-provider-and-service. The data was accessed in October 2024.

Funding Statement

The author(s) received no specific funding for this work.

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Decision Letter 0

Muhammad Muntazir Mehdi Khan

6 Jun 2025

-->PONE-D-25-20867-->-->Gender Differences in Provider Practice Characteristics and Medicare Payment & Services Among Diagnostic Radiologists-->-->PLOS ONE

Dear Dr. Malhotra,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Jul 21 2025 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:-->

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

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If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

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We look forward to receiving your revised manuscript.

Kind regards,

Muhammad Muntazir Mehdi Khan, M.B.B.S.

Academic Editor

PLOS ONE

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[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

-->Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. -->

Reviewer #1: Yes

Reviewer #2: Partly

**********

-->2. Has the statistical analysis been performed appropriately and rigorously? -->

Reviewer #1: Yes

Reviewer #2: No

**********

-->3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.-->

Reviewer #1: No

Reviewer #2: Yes

**********

-->4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.-->

Reviewer #1: Yes

Reviewer #2: Yes

**********

-->5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)-->

Reviewer #1: The manuscript presents an original and timely analysis of gender-based disparities in practice characteristics and Medicare payments among diagnostic radiologists. The topic is highly relevant, and the analysis is based on a large, publicly available dataset, with appropriate statistical comparisons. The manuscript is technically sound, and the conclusions are well-supported by the data. However, I recommend minor revisions to address key clarifications and align with PLOS ONE’s standards for reproducibility and transparency.

Abstract: On Line 28, correct “differences among radiologists is poorly understood” to “are poorly understood.” On Lines 57–60, clarify the payment comparison: “female radiologists received 86% of the total Medicare payments received by male radiologists.” Remove space before semicolons in statistical reporting (e.g., Line 55: “9,859 ;” → “9,859;”). This line is a little confusing, please fix this.

Methods (Lines 91–141): The methodology is appropriate, but a few key variable definitions are missing. Please clarify:

How gender was assigned (e.g., from NPPES or another linked source) — not specified in current version.

How academic vs. non-academic status was defined (Line 112 onward).

How urban vs. rural practice was classified (Line 114).

How practice size was measured (Line 116).

Line 120 contains a typo: correct “breath of practice” to “breadth of practice.” On Line 133, clarify whether a two-tailed alpha level (e.g., α = 0.05) was used and if any R packages were applied in analysis.

Results (Lines 142–191): The results are clearly presented and statistically robust. To improve clarity:

On Lines 158–161, rephrase for interpretability: “34.2% of academic radiologists were female, compared to 22.6% in non-academic settings.”

On Line 164, clarify that 64.9% refers to female representation within breast imaging.

On Lines 142–145, specify how p-values for time trends were calculated (e.g., test for trend vs simple comparison).

For statements like “per-service payments were similar within subspecialties” (Line 172), consider adding whether statistical testing confirmed this or clarify as an observation.

Discussion (Lines 192–247): Well-structured and grounded in existing literature. On Line 193, fix heading typo: “DICUSSION” → “DISCUSSION.” Line 184 contains a grammatical error: “the a prior study” → “a prior study.” On Line 159, temper speculation: replace “will plateau” with “may plateau.” Similarly, Line 107–110 speculates about non-Medicare income sources — please clearly frame this as a hypothesis. Consider briefly discussing implications or areas for future research (e.g., understanding drivers of volume differences).

Limitations (Lines 248–266): Strong and transparent. On Line 252, rephrase “only <0.1%” to “fewer than 0.1%.” Consider noting that working hours or FTE status were not available and could influence payment differences. Also mention that multivariable adjustment was not performed.

Conclusion (Lines 263–266): Appropriate and data-aligned. Line 264 may read better as: “payments per service were higher for female radiologists than for males overall, but were comparable between genders within the same subspecialty.”

Data Availability (Lines 93–95, 267–268): Current statement (“CMS Public files”) is insufficient. Please expand to include dataset name, years used, and a direct URL (e.g., “https://data.cms.gov/...”).

Minor Style Issues: Maintain consistent terminology (e.g., “female/male radiologists”), fix small typos, and add table/figure cross-references where appropriate in Results.

In summary, this is a strong manuscript that requires minor revisions to address transparency, clarify definitions, and polish a few points of language and formatting. Once addressed, it will meet the publication standards of PLOS ONE.

Reviewer #2: In the study by Malhotra et al., the authors sought to compare Medicare payments between female and male diagnostic radiologists. Overall, this is an interesting study and is well written. I have a major concern:

Why did the authors not conduct a multivariate regression to see an independent association between and medicare payments? From the results, it is seen that female radiologists are more likely to be in academic practice compared to male radiologists. The practice type could be a confounder/ effect modifier and therefore, we cannot draw conclusions without multivariate analysis.

**********

-->6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.-->

Reviewer #1: Yes: N/A

Reviewer #2: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

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PLoS One. 2026 Jun 5;21(6):e0349413. doi: 10.1371/journal.pone.0349413.r002

Author response to Decision Letter 1


10 Jul 2025

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Partly

Response: We have added to the analysis as suggested.

________________________________________

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: No

Response: We have added to the statistical analysis as suggested and performed multivariable regression- this has been added to the Methods, Results and Discussion sections.

________________________________________

3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

Response: We have now added the Data Availability Statement and clarified that the data is publicly available and provided the source.

________________________________________

4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: Yes

________________________________________

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: The manuscript presents an original and timely analysis of gender-based disparities in practice characteristics and Medicare payments among diagnostic radiologists. The topic is highly relevant, and the analysis is based on a large, publicly available dataset, with appropriate statistical comparisons. The manuscript is technically sound, and the conclusions are well-supported by the data. However, I recommend minor revisions to address key clarifications and align with PLOS ONE’s standards for reproducibility and transparency.

Abstract: On Line 28, correct “differences among radiologists is poorly understood” to “are poorly understood.” On Lines 57–60, clarify the payment comparison: “female radiologists received 86% of the total Medicare payments received by male radiologists.” Remove space before semicolons in statistical reporting (e.g., Line 55: “9,859 ;” → “9,859;”). This line is a little confusing, please fix this.

Response: We have now incorporated the suggestions and made corrections.

Methods (Lines 91–141): The methodology is appropriate, but a few key variable definitions are missing. Please clarify:

How gender was assigned (e.g., from NPPES or another linked source) — not specified in current version.

How academic vs. non-academic status was defined (Line 112 onward).

How urban vs. rural practice was classified (Line 114).

How practice size was measured (Line 116).

Response: We have now incorporated the suggestions and clarified the definition sources.

Line 120 contains a typo: correct “breath of practice” to “breadth of practice.” On Line 133, clarify whether a two-tailed alpha level (e.g., α = 0.05) was used and if any R packages were applied in analysis.

Results (Lines 142–191): The results are clearly presented and statistically robust. To improve clarity:

On Lines 158–161, rephrase for interpretability: “34.2% of academic radiologists were female, compared to 22.6% in non-academic settings.”

On Line 164, clarify that 64.9% refers to female representation within breast imaging.

Response: We have now incorporated the suggestions and made corrections.

On Lines 142–145, specify how p-values for time trends were calculated (e.g., test for trend vs simple comparison).

Response: We have now incorporated the suggestion and added to Methods and Results. Trends in payment amounts over time were determined with a time-series analysis with a two-tailed alpha level (α = 0.05).

For statements like “per-service payments were similar within subspecialties” (Line 172), consider adding whether statistical testing confirmed this or clarify as an observation.

Response: We have now incorporated the suggestion.

Discussion (Lines 192–247): Well-structured and grounded in existing literature. On Line 193, fix heading typo: “DICUSSION” → “DISCUSSION.” Line 184 contains a grammatical error: “the a prior study” → “a prior study.” On Line 159, temper speculation: replace “will plateau” with “may plateau.” Similarly, Line 107–110 speculates about non-Medicare income sources — please clearly frame this as a hypothesis. Consider briefly discussing implications or areas for future research (e.g., understanding drivers of volume differences).

Response: We have now incorporated the suggestions and made corrections.

Limitations (Lines 248–266): Strong and transparent. On Line 252, rephrase “only <0.1%” to “fewer than 0.1%.” Consider noting that working hours or FTE status were not available and could influence payment differences. Also mention that multivariable adjustment was not performed.

Response: We have now incorporated the suggestions and made corrections.

Conclusion (Lines 263–266): Appropriate and data-aligned. Line 264 may read better as: “payments per service were higher for female radiologists than for males overall, but were comparable between genders within the same subspecialty.”

Response: We have now incorporated the suggestions and made corrections.

Data Availability (Lines 93–95, 267–268): Current statement (“CMS Public files”) is insufficient. Please expand to include dataset name, years used, and a direct URL (e.g., “https://data.cms.gov/...”).

Response: We have now incorporated the suggestions and made corrections.

Minor Style Issues: Maintain consistent terminology (e.g., “female/male radiologists”), fix small typos, and add table/figure cross-references where appropriate in Results.

In summary, this is a strong manuscript that requires minor revisions to address transparency, clarify definitions, and polish a few points of language and formatting. Once addressed, it will meet the publication standards of PLOS ONE.

Reviewer #2: In the study by Malhotra et al., the authors sought to compare Medicare payments between female and male diagnostic radiologists. Overall, this is an interesting study and is well written. I have a major concern:

Why did the authors not conduct a multivariate regression to see an independent association between and medicare payments? From the results, it is seen that female radiologists are more likely to be in academic practice compared to male radiologists. The practice type could be a confounder/ effect modifier and therefore, we cannot draw conclusions without multivariate analysis.

Response: We have now incorporated the suggestions and performed multivariate regression- this has been added to the Methods, Results and Discussion sections.

________________________________________

6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: Yes: N/A

Reviewer #2: No

Attachment

Submitted filename: PLOS Reviewers.docx

pone.0349413.s002.docx (18.8KB, docx)

Decision Letter 1

Lorenzo Faggioni

10 Mar 2026

-->PONE-D-25-20867R1-->-->Gender Differences in Provider Practice Characteristics and Medicare Payment & Services Among Diagnostic Radiologists-->-->PLOS One

Dear Dr. Malhotra,

Thank you for submitting your revised manuscript to PLOS ONE. Several issues have been addressed, but other ones have been raised by the reviewers in the last review round. Therefore, we invite you to submit a further revised version of the manuscript that addresses the latest points.

Please submit your revised manuscript by Apr 24 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:-->

  • A letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: https://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

We look forward to receiving your revised manuscript.

Kind regards,

Lorenzo Faggioni, M.D., Ph.D.

Academic Editor

PLOS One

Journal Requirements:

If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

-->Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.-->

Reviewer #3: (No Response)

Reviewer #4: (No Response)

**********

-->2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented. -->

Reviewer #3: Partly

Reviewer #4: Yes

**********

-->3. Has the statistical analysis been performed appropriately and rigorously? -->

Reviewer #3: No

Reviewer #4: Yes

**********

-->4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.-->

Reviewer #3: Yes

Reviewer #4: Yes

**********

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Reviewer #3: Yes

Reviewer #4: Yes

**********

-->6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)-->

Reviewer #3: Doctors --

OVERALL

This manuscript addresses an interesting, policy-relevant question; the CMS Physician/Other Practitioners public files are a reasonable source for a descriptive look at radiology workload and Medicare payments.

Your headline findings: women are ~25% of diagnostic radiologists; more likely to be academic, urban, in large groups, and in certain subspecialties (notably breast); women have lower total Medicare payments but higher payment per service overall, with parity within the same subspecialty. All of that is clearly stated.

RECOMMENDATIONS

1. Adjust beyond bivariate tests.

Right now, means/medians are compared with t-tests/Wilcoxon. That’s not enough for a question this confounded (years in practice, region, urbanicity, practice size, subspecialty mix, year). Add multivariable models (e.g., panel OLS/GLM with radiologist and year fixed effects or at least covariate adjustment with clustered SEs by NPI).

Report adjusted differences and CIs.

2. Decompose “payment per service.”

Your own discussion concedes this metric reflects code mix, professional vs global billing, facility vs non-facility, and regional GPCI, not “pay” per se. Do a mix-adjustment: (i) show the top CPT/HCPCS distributions by sex; (ii) reweight to a common code mix; (iii) report a case-mix–adjusted payment per service. That will test whether the 18% higher female PPS is mix, geography, or true per-code differences (which should be zero under the fee schedule).

Also break out professional-only vs global where feasible.

3. Subspecialty classification transparency.

You infer subspecialty by >50% wRVUs using NITOS modality/body-region mapping. Clever idea — recommend to document it fully in the Methods (code lists, thresholds, sensitivity with 60%/70% cutoffs). Right now the summary references prior validation but your implementation details (exact crosswalks) need to be reproducible. Deposit the mapping.

4. Define “academic vs non-academic,” “urban vs rural,” and “years in practice.”

You cite practice location and NPPES for “years in practice,” but the operational definitions aren’t spelled out (RUCA vs MSA? Years since NPI enumeration != years in practice). Add precise algorithms and references.

5. Repeated measures / clustering.

Are observations pooled across 2017–2021 at the physician-year level? If so, your tests must account for within-physician correlation across years (clustered SEs) and secular trends (year fixed effects). The time-trend figure suggests a panel; analyze it as such.

6. Tables contain obvious inconsistencies.

In Table 1, the “All years” column shows tiny denominators (e.g., “Academic 34.2% (221/948)”) that don’t match the reported overall N (33,029). Audit and correct these lines before anything else. Similar spot-checks across Table 3 are prudent.

7. Terminology and source for “gender.”

State explicitly how “gender” is obtained in CMS files (binary sex field, self-report, inference?). Use consistent terminology and acknowledge limitations (non-binary not captured).

8. Scope the inference carefully.

You study FFS Medicare claims only. Don’t imply salary conclusions or “pay gaps”; these are Medicare reimbursements, not total compensation, and exclude Medicare Advantage/commercial. You mention this in Limitations—bring that caution forward into the Abstract and Conclusions.

9. Data/code availability.

In the spirit of replicability: provide exact dataset names/years/URLs and deposit all code and crosswalks (wRVU/NITOS subspecialty assignment, urban/rural rules, academic flag) in a public repo. The current data statement should point precisely to those sources.

MINOR NOTES

- Use rates per radiologist-year (or per 1,000 services) in the text instead of raw totals; keep totals to the tables.

- Report both means and medians for skewed financial variables.

- Tighten typos (e.g., “DICUSSION”), and standardize style in tables/figures.

ASSESSMENT

Publishable as a descriptive claims analysis once you fix the table errors, add proper adjustment/mix-decomposition, define classification rules, and scope claims to Medicare reimbursements (not income).

The current unadjusted comparisons over-interpret the 18% PPS difference.

Reviewer #4: Thank you for the opportunity to review this manuscript. The manuscript can benefit from the following revisions:

1) The manuscript does not define how “academic” radiologists were identified. Was this based on practice setting codes, affiliation with teaching hospitals, or another CMS variable? Please specify in the Methods.

2) The result that females receive 18% higher payment per service is interesting.

a) Could it be that female radiologists perform more complex/higher RVU studies?

b) Are they more likely to bill for the technical component (e.g., in breast imaging)?

c) Is there a geographic concentration in higher-GPCI regions?

A brief discussion should be added for these points.

3) The use of wRVU-based assignment is validated, but it remains an approximation.

4) The authors should explain that why they chose only medicare population because the real pay disparity lies in the commercial payer rates.

5) The authors note that female representation is not increasing among newer radiologists (1–9 years) compared to mid-career (10–24 years), suggesting a potential plateau. This is an important observation and should be discussed in the context of national workforce trends and potential barriers to entry.

**********

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Reviewer #3: No

Reviewer #4: No

**********

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PLoS One. 2026 Jun 5;21(6):e0349413. doi: 10.1371/journal.pone.0349413.r004

Author response to Decision Letter 2


20 Apr 2026

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #3: Doctors --

OVERALL

This manuscript addresses an interesting, policy-relevant question; the CMS Physician/Other Practitioners public files are a reasonable source for a descriptive look at radiology workload and Medicare payments.

Your headline findings: women are ~25% of diagnostic radiologists; more likely to be academic, urban, in large groups, and in certain subspecialties (notably breast); women have lower total Medicare payments but higher payment per service overall, with parity within the same subspecialty. All of that is clearly stated.

RECOMMENDATIONS

1. Adjust beyond bivariate tests.

Right now, means/medians are compared with t-tests/Wilcoxon. That’s not enough for a question this confounded (years in practice, region, urbanicity, practice size, subspecialty mix, year). Add multivariable models (e.g., panel OLS/GLM with radiologist and year fixed effects or at least covariate adjustment with clustered SEs by NPI).

Report adjusted differences and CIs.

Response: Thank you for your comment. In our analysis, we aggregated the data at the NPI level for each individual calendar year, such that each observation represents a physician-year. While this structure allows for repeated observations of the same physician across years, practice patterns may vary meaningfully over time (e.g., due to sabbaticals, transitions to part-time work, or retirement). Because these factors cannot be reliably captured in the dataset, we did not consider it appropriate to pool observations across years at the physician level.

Also, we do not observe substantial year-to-year variations, and the calendar year was not considered a significant confounder. Accordingly, we utilized unadjusted comparisons (t-tests and Wilcoxon rank-sum tests) to evaluate differences between groups.

2. Decompose “payment per service.”

Your own discussion concedes this metric reflects code mix, professional vs global billing, facility vs non-facility, and regional GPCI, not “pay” per se. Do a mix-adjustment: (i) show the top CPT/HCPCS distributions by sex; (ii) reweight to a common code mix; (iii) report a case-mix–adjusted payment per service. That will test whether the 18% higher female PPS is mix, geography, or true per-code differences (which should be zero under the fee schedule).

Also break out professional-only vs global where feasible.

Response: We agree that the observed difference in payment per service likely reflects variations in code mix, billing composition, and geographic factors. While a formal case-mix adjustment falls outside the macro-level scope of our study, Table 1 outlines broad distributional differences in practice composition by gender. To address this important point, we have added a sentence to the Discussion clarifying that this metric is driven by differences in subspecialty and modality mix.

3. Subspecialty classification transparency.

You infer subspecialty by >50% wRVUs using NITOS modality/body-region mapping. Clever idea — recommend to document it fully in the Methods (code lists, thresholds, sensitivity with 60%/70% cutoffs). Right now the summary references prior validation but your implementation details (exact crosswalks) need to be reproducible. Deposit the mapping.

Response: Thank you for your comment. We will document it in the Methods. This threshold and classification strategy were derived from the methodology described by Rosenkrantz et al. (J Am Coll Radiol, 2017), which validated a claims-based approach to subspecialty assignment using Medicare data. We adapted their approach by applying the same >50% wRVU threshold to assign each radiologist a single dominant subspecialty based on their distribution of billed services.

Rosenkrantz AB, Wang W, Hughes DR, Ginocchio LA, Rosman DA, Duszak R Jr. Academic Radiologist Subspecialty Identification Using a Novel Claims-Based Classification System. AJR Am J Roentgenol. 2017 Jun;208(6):1249-1255. doi: 10.2214/AJR.16.17323. Epub 2017 Mar 16. Erratum in: AJR Am J Roentgenol. 2017 Aug;209(2):472. doi: 10.2214/AJR.17.18609. PMID: 28301213.

Rosenkrantz AB, Wang W, Bodapati S, Hughes DR, Duszak R Jr. Private Practice Radiologist Subspecialty Classification Using Medicare Claims. J Am Coll Radiol. 2017 Nov;14(11):1419-1425. doi: 10.1016/j.jacr.2017.04.025. Epub 2017 Jun 30. PMID: 28673776.

4. Define “academic vs non-academic,” “urban vs rural,” and “years in practice.”

You cite practice location and NPPES for “years in practice,” but the operational definitions aren’t spelled out (RUCA vs MSA? Years since NPI enumeration != years in practice). Add precise algorithms and references.

Response: Thank you for your comment. We have clarified the operational definitions in the Methods section. The academic status of practices associated with radiologists in the CMS files was obtained from the Harvey L. Neiman Health Policy Institute. Per the methodology provided by the institute, practices were classified as academic if their names contained terms such as “university,” “faculty,” “college,” or “school,” and were further validated through manual review against the list of diagnostic radiology residency programs provided by the AAMC. Urban versus rural status was determined using Rural-Urban Commuting Area (RUCA) codes based on practice ZIP code. “Years in practice” was derived from the physician’s medical school graduation year as reported in the publicly available National Plan & Provider Enumeration System (NPPES) database and linked via NPI.

5. Repeated measures / clustering.

Are observations pooled across 2017–2021 at the physician-year level? If so, your tests must account for within-physician correlation across years (clustered SEs) and secular trends (year fixed effects). The time-trend figure suggests a panel; analyze it as such.

Response: Thank you for this comment. Our dataset is structured at the physician-year level, with each observation representing a unique NPI in a given calendar year. While this allows for repeated observations of the same physician across years, we did not model the data as a longitudinal panel. This decision was based on the potential for meaningful year-to-year variation in individual practice patterns (e.g., sabbaticals, transitions to part-time work, or retirement), which cannot be reliably captured in the dataset.

Also, we do not observe substantial year-to-year variations, and the calendar year was not considered a significant confounder. Accordingly, we utilized unadjusted comparisons (t-tests and Wilcoxon rank-sum tests) to evaluate differences between groups.

6. Tables contain obvious inconsistencies.

In Table 1, the “All years” column shows tiny denominators (e.g., “Academic 34.2% (221/948)”) that don’t match the reported overall N (33,029). Audit and correct these lines before anything else. Similar spot-checks across Table 3 are prudent.

Response: The denominators in Table 1 reflect only physicians with available data for the specified variable (e.g., practice type. As such, we excluded analysis like “Academic vs Non Academic” for physicians who did not have data available.

7. Terminology and source for “gender.”

State explicitly how “gender” is obtained in CMS files (binary sex field, self-report, inference?). Use consistent terminology and acknowledge limitations (non-binary not captured).

Response: Thank you for your comment. Gender was obtained from the CMS dataset as a self-reported, binary variable (male/female). We have clarified this in the Methods section and now acknowledge this as a limitation, as non-binary gender identities are not captured in the dataset.

8. Scope the inference carefully.

You study FFS Medicare claims only. Don’t imply salary conclusions or “pay gaps”; these are Medicare reimbursements, not total compensation, and exclude Medicare Advantage/commercial. You mention this in Limitations—bring that caution forward into the Abstract and Conclusions.

Response: Thank you for your comment. We agree that our inferences should be carefully scoped to reflect that the analysis is based on FFS Medicare claims data and does not represent total physician compensation. We have detailed this in the limitations section and added a sentence about this in the discussion.

9. Data/code availability.

In the spirit of replicability: provide exact dataset names/years/URLs and deposit all code and crosswalks (wRVU/NITOS subspecialty assignment, urban/rural rules, academic flag) in a public repo. The current data statement should point precisely to those sources.

Response: Thank you for your comment. All data used in this study are publicly available, and specific references to the datasets, including the CMS Medicare Fee-for-Service Provider Utilization and Payment Data (2017–2021) and the National Plan & Provider Enumeration System (NPPES), are provided in the Methods section and references. The code is available from the authors upon request.

MINOR NOTES

- Use rates per radiologist-year (or per 1,000 services) in the text instead of raw totals; keep totals to the tables.

- Report both means and medians for skewed financial variables.

- Tighten typos (e.g., “DICUSSION”), and standardize style in tables/figures.

Thank you for your comment.

Attachment

Submitted filename: ResponsetoReviewCL_MKedits.docx

pone.0349413.s003.docx (33.5KB, docx)

Decision Letter 2

Lorenzo Faggioni

29 Apr 2026

Gender Differences in Provider Practice Characteristics and Medicare Payment & Services Among Diagnostic Radiologists

PONE-D-25-20867R2

Dear Dr. Malhotra,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Academic Editor

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Acceptance letter

Lorenzo Faggioni

PONE-D-25-20867R2

PLOS One

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Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    Attachment

    Submitted filename: PLOS Reviewers.docx

    pone.0349413.s002.docx (18.8KB, docx)
    Attachment

    Submitted filename: ResponsetoReviewCL_MKedits.docx

    pone.0349413.s003.docx (33.5KB, docx)

    Data Availability Statement

    DATA AVAILABILITY STATEMENT This study used publicly available data from the CMS Medicare Physician & Other Practitioners dataset (2017–2021). The data are accessible at: https://data.cms.gov/provider-summary-by-type-of-service/medicare-physician-other-practitioners-by-provider-and-service. The data was accessed in October 2024.


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