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. 2026 Jun 15:21925682261458255. Online ahead of print. doi: 10.1177/21925682261458255

Posterior Transdural Decompression for Thoracic Disc Herniation Causing Myelopathy: A Systematic Review of Outcomes and Safety

Hussein Akil 1, Deya AlWady 2,✉, Rodrigo Muscogliati 3, Mohammad Badra 4, Rami Abou Faour 5, Spyridon Komaitis 2, Khalid M Salem 2, Zeinab Nahle 6, Farwa Abbas 2, Elie Najjar 2
PMCID: PMC13269113  PMID: 42295993

Abstract

Study Design

Systematic Review.

Objective

To evaluate neurological outcomes, complication rates, and operative characteristics of the posterior transdural approach for thoracic disc herniation causing myelopathy.

Methods

A systematic review was conducted in accordance with PRISMA 2020 guidelines. MEDLINE, Embase, and PubMed were searched from inception to January 2026. Studies including adult patients undergoing posterior transdural decompression for thoracic disc herniation were eligible. Two reviewers independently performed study selection, data extraction, and methodological quality assessment using the Joanna Briggs Institute checklist for case series. Extracted variables included patient demographics, disc characteristics, operative details, neurological outcomes, follow-up duration, and complications.

Results

Seven Level IV studies comprising 74 patients were included. The weighted mean age was 52.8 years, and 70.3% of discs were calcified. The posterior transdural corridor was utilized in all cases; however, ventral durotomy was performed in 72 of 74 patients (97.3%), with preservation of the ventral dura reported in selected cases. Across studies reporting extractable outcome data, 76% of patients demonstrated neurological improvement, 21% remained stable, and 1.4% experienced persistent neurological deterioration. Transient postoperative neurological worsening occurred in 9.5% of patients and resolved in nearly all cases. Cerebrospinal fluid leakage occurred in 4.1%, with reoperation required in 2.7%. No mortality was reported. Reported operative time varied across studies, ranging from a mean of 124 min in the prospective cohort to a mean of 241 min in the transpedicular–transdural series, with other studies reporting median values between 152 and 210 min.

Conclusion

Posterior transdural decompression for thoracic disc herniation causing myelopathy is associated with favorable neurological outcomes and a low rate of permanent morbidity, even in predominantly calcified or giant disc pathology. In appropriately selected patients, this technique appears to provide effective ventral decompression with an acceptable safety profile.

Keywords: thoracic spine, thoracic disc herniation, transdural approach, complications

Introduction

Thoracic disc herniation (TDH) is an uncommon but potentially disabling cause of myelopathy, accounting for less than 1% of symptomatic disc disease. Owing to the narrow thoracic spinal canal, kyphotic alignment, and frequent ventral or calcified disc morphology, surgical management remains technically demanding. Historically, simple laminectomy was associated with poor neurological outcomes due to inadequate ventral decompression and spinal cord manipulation, prompting the development of alternative approaches, including transthoracic, thoracoscopic, transpedicular, costotransversectomy, and transfacet pedicle-sparing techniques.1,2

Although anterior and thoracoscopic approaches provide direct ventral access, they are associated with approach-related morbidity, including pulmonary and cardiothoracic complications. Posterolateral strategies aim to reduce systemic morbidity but may provide limited visualization of centrally located or densely calcified discs. The posterior transdural approach has emerged as an alternative technique that allows direct visualization and removal of ventral pathology through a posterior corridor while avoiding thoracotomy. However, this technique requires intentional dural opening and manipulation of neural structures, raising concerns regarding cerebrospinal fluid leakage and neurological injury.

Despite increasing use in selected cases, the existing literature on transdural decompression for thoracic myelopathy consists primarily of small retrospective case series. Outcomes, complication profiles, and operative characteristics have not been systematically synthesised, and the relative safety of this approach—particularly in calcified or giant disc pathology—remains incompletely defined.

The purpose of this study was to perform a systematic review of published case series reporting outcomes of posterior transdural decompression for thoracic disc herniation presenting with myelopathy. We aimed to evaluate neurological outcomes, complication rates, and operative metrics in order to better define the safety profile and clinical role of this technique.

Methods

Protocol and Reporting

This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA 2020) guidelines. 3 The review protocol was developed a priori and followed throughout the study.

Data Sources and Search Strategy

A comprehensive electronic search was performed in the following databases from inception to the final search date, January 2026: MEDLINE, Embase, and PubMed. The search strategy combined controlled vocabulary (eg, MeSH/Emtree terms) with free-text keywords and applied Boolean operators, truncation, and database-specific syntax. Key concepts included (1) thoracic disc herniation (eg, thoracic disc herniation, thoracic vertebrae, disc, disk, herniation, prolapse, extrusion, protrusion) and (2) surgical approach (eg, transdural, trans-dural, intradural, intra-dural, posterior, dorsal, transpedicular, laminectomy, laminoplasty, costotransversectomy).

No language limits were applied during the search. During screening, only English-language full-text articles were included due to feasibility constraints.

Eligibility Criteria

Studies were selected according to the PICOTS framework as follows:

  • • Population: Adult patients (≥18 years) diagnosed with symptomatic thoracic disc herniation undergoing surgical management. Studies including patients with myelopathy, radiculopathy, axial thoracic pain, or mixed presentations were eligible. Both calcified and non-calcified thoracic disc herniations, as well as primary and recurrent cases, were included.

  • • Intervention: Transdural surgical approach for thoracic disc herniation, including posterior transdural discectomy, intradural discectomy, or surgical techniques involving intentional durotomy to facilitate disc removal.

  • • Comparator: When available, comparator groups may include alternative surgical approaches for thoracic disc herniation, such as transthoracic, thoracoscopic, costotransversectomy, lateral extracavitary, transfacet, or other posterolateral approaches. However, studies without a comparator group were also considered eligible.

  • • Outcomes: Eligible studies must report at least one clinical, perioperative, radiological, or complication-related outcome. Clinical outcomes may include measures of neurological status, functional recovery, or pain improvement. Perioperative outcomes may include operative time, estimated blood loss, and length of hospital stay. Complication outcomes may include cerebrospinal fluid leakage, neurological deterioration, infection, reoperation, or mortality. Radiological outcomes such as adequacy of decompression or recurrence were also considered.

  • • Timing: Any postoperative follow-up duration.

  • • Study design: Randomized controlled trials, prospective or retrospective cohort studies, case-control studies, and case series were eligible.

Exclusion Criteria

Studies were excluded if they involved pediatric patients, non-thoracic disc herniations, or do not specifically evaluate a transdural surgical approach. Case reports, review articles, editorials, conference abstracts without full data, technical notes lacking clinical outcomes, and cadaveric or biomechanical studies were excluded. Studies not reporting postoperative outcomes or with insufficient methodological detail were also excluded, as will non-English publications.

Study Selection

Two reviewers independently screened titles and abstracts, followed by full-text review. Disagreements were resolved by consensus with the senior author. A total of 3056 records were identified, of which 992 duplicates were removed. After screening 2064 abstracts, 7 studies met the inclusion criteria, as shown in Figure 1.

Figure 1.

Figure 1.

PRISMA chart

Data Extraction

Two reviewers independently performed data extraction using a standardized form that included study characteristics (author, year, country, design), patient demographics and clinical presentation, radiological features of the thoracic disc herniation (level, location, calcification, canal occupation), detailed surgical technique variables related to the transdural approach, perioperative parameters (operative time, blood loss, length of stay), postoperative neurological and functional outcomes, duration of follow-up, and reported intraoperative and postoperative complications.

Quality Assessment

Methodological quality of the included studies was independently assessed by two reviewers using the Joanna Briggs Institute (JBI) Critical Appraisal Checklist for Case Series. 4 Each study was evaluated across the checklist domains addressing clear inclusion criteria, standardized and reliable measurement of condition, consecutive inclusion of participants, complete inclusion, reporting of demographics, clinical information, outcomes, follow-up, and appropriateness of statistical analysis. Discrepancies between reviewers were resolved through discussion to reach consensus. The results of the quality assessment were summarized in a standardized table (Table 1).

Table 1.

Risk of Bias Assessment Using JBI Critical Appraisal Checklist for Case Seeies

Question Bocchetti, 2017 Coppes, 2012 Dogan, 2023 Moon, 2010 Negwer, 2020 Alam, 2025 Komaiti s, 2025
1. Were there clear criteria for inclusion in the case series? No Yes Yes No Yes Yes Yes
2. Was the condition measured in a standard, reliable way for all participants included in the case series? Yes Yes Yes Yes Yes Yes Yes
3. Were valid methods used for identification of the condition for all participants included in the case series? Yes Yes Yes Yes Yes Yes Yes
4. Did the case series have consecutive inclusion of participants? No Yes Yes No Yes Unclear Yes
5. Did the case series have complete inclusion of participants? No Yes Yes No Yes Yes Yes
6. Was there clear reporting of the demographics of the participants in the study? Yes Yes Yes Yes Yes Yes Yes
7. Was there clear reporting of clinical information of the participants? Yes Yes Yes Yes Yes Yes Yes
8. Were the outcomes or follow up results of cases clearly reported? Yes Yes Yes Yes Yes Yes Yes
9. Was there clear reporting of the presenting site(s)/clinic(s) demographic information? Yes Yes Yes Yes Yes Yes Yes
10. Was statistical analysis appropriate? N/A Yes Yes N/A Yes Yes Yes

Results

Seven Level IV studies5-11 comprising 74 patients were included (Table 1). Six were retrospective case series5-11 and one was a prospective observational cohort. 10 The pooled cohort included 42 males and 32 females (male-to-female ratio 1.3:1). The weighted mean age across all studies was 52.8 years, with individual study means ranging from 45.2 to 58.0 years and an overall reported age range of 17 to 94 years.

Calcified disc herniations were reported in 52 of 74 patients (70.3%). Giant disc herniations, defined as occupying more than 40-50% of the spinal canal, were explicitly described in 19 patients (25.7%), all of whom were included in two dedicated giant-disc cohorts.7,11 Ventral dural opening was performed in 72 of 74 patients (97.3%), ventral dura preservation was reported by Bocchetti et al. 9 Posterior instrumentation was used in 7 patients (9.5%), all within a single study. 11 Intraoperative neuromonitoring was reported in four studies7-9,11 and was utilized in 28 of 74 patients (37.8%).

Mean follow-up duration varied substantially across studies, ranging from 1.0 to 24.2 months, with the longest individual follow-up extending to 66 months. Detailed study-level characteristics are presented in Table 2.

Table 2.

Studies Demographics and Characteristics

Study Design LOE n Age (yrs) mean ± SD (Range) M/F Calcified n (%) Giant n (%) Ventral dura Fixation IONM Follow- up (months)
Moon, 2010 5 Retrospective IV 3 57.3 ± 15.6 (41-72) 2/1 0 0 Opened No No 16.0 ± 3.5
Coppes, 2012 6 Retrospective IV 13 55.4 ± 18.4 (20-79) 9/4 30.8 46.2 Opened No No 24.2 ± 19.4
Negwer, 2020 7 Retrospective IV 12 57.4 ± 21.7 (28-94) 4/8 100 100 Opened No Yes Median 10.0
Dogan, 2023 8 Retrospective IV 7 51.4 ± 19.7 (17-74) 5/2 71.4 0 Opened No Yes 13.3 ± 3.9
Bocchetti, 2017 9 Retrospective IV 2 51.5 ± 21.9 (36-67) 0/2 100% 0 Preserved No Yes 6.0 ± 0
Alam, 2025 10 Prospective IV 30 45.2 ± 9.6 (28-69) 18/12 73.3 0 Opened No No 1.0 ± 0.0
Komaitis, 2025 11 Retrospective IV 7 58.0 ± 10.2 (37-68) 4/3 100 100 Opened Yes Yes 3.0 ± 0.0

Technical Strategies

Across the included studies, several recurring technical strategies were described to improve ventral access while minimizing spinal cord manipulation. These included CSF drainage after durotomy, sectioning or suspension of the dentate ligament, microscope-assisted visualization, gentle or gravity-assisted cord displacement, and avoidance of forceful disc-space exploration. For calcified or giant discs, authors described controlled internal debulking or piecemeal removal using hooks, punches, high-speed drilling, CUSA, or ultrasonic bone instruments. Intraoperative neuromonitoring was reported in four studies and was used in 28 of 74 patients, most commonly in contemporary series involving calcified or giant discs. Detailed study-level technical strategies are provided in Supplemental Table 1.

Clinical Neurological Outcome

Neurological assessment methods varied across studies and included Frankel grade, ASIA scale, mJOA, and Nurick score, with two early series reporting qualitative clinical outcomes only.5,9 Across the five studies providing individual-level outcome categorisation,5-11 outcome data were extractable for 34 patients with available follow-up. Of these, 26 (76%) demonstrated neurological improvement, 7 (21%) remained stable, and 1 (3%) experienced persistent deterioration at final follow-up. Transient postoperative neurological worsening was reported in two series but resolved in all except one patient7,11 (Table 3).

Table 3.

Summary of Outcomes

Study n Baseline deficit Outcome measure Improved Stable Worsened Notes
Moon, 2010 5 3 1 sensory-only; 2 mild motor (4/5) ± sensory Qualitative 3 0 0 No formal score used
Coppes, 2012 6 13 All myelopathic; Frankel C (3), D (8), E (2) Frankel + Likert 12 1 0 Frankel improved in 6; clinical improvement in 12
Negwer, 2020 7 12 All myelopathic; mean mJOA 15 mJOA 6/9 3/9 0 Follow-up in 9/12; transient deterioration resolved
Dogan, 2023 8 7 All myelopathic; ASIA ASIA NR NR 0 No separation of improved vs stable
Bocchetti, 2017 9 2 Both myelopathic; mild paraparesis + sensory ± bladder dysfunction Qualitative 2 0 0 Small preliminary series; ventral dura preserved
Alam, 2025 10 30 Mean mJOA 13.1 ± 2.4 mJOA NR NR 0 Only mean improvement reported (13.1→16.3); no individual-level outcome distribution
Komaitis, 2025 11 7 Moderate–severe myelopathy; mean Nurick 3.9 Nurick + Modified Frankel 3 3 1 1 persistent deficit; transient deterioration in 1 resolved

Two studies8,10 did not provide categorical patient-level distribution. Dogan et al. 8 reported that all seven patients were neurologically stable or improved at follow-up, with no deterioration. Alam et al. 10 demonstrated significant mean mJOA improvement (13.1 to 16.3; P < 0.001) in a prospective cohort of 30 patients, with no permanent neurological deficits reported, although individual outcome stratification was not available.

Across the total pooled cohort of 74 patients, only one case of persistent neurological deterioration was reported (1.4%), with the majority of patients demonstrating neurological improvement or stability at final follow-up.

Follow-up duration varied substantially between studies, limiting comparability of long-term neurological recovery rates.

Dural Repair

Dural repair techniques varied across studies (Table 4). Ventral dural management included preservation in selected cases,9,10 patching with biological or synthetic materials such as TachoSil or Tissuedura,6,11 and fibrin sealant-based inlay–outlay techniques. 7 In several series, suturing of the ventral dura was not required due to adherence to the posterior longitudinal ligament.5,8

Table 4.

Dural Repair Techniques

Study ID Ventral dura repair technique Dorsal dura repair technique
Bocchetti, 2017 Ventral dura was preserved Watertight manner
Coppes, 2012 Patched with Tissuedura or TachoSil + extradurally sealed with fibrin glue Running sutures and sealed with TachoSil and/or fibrin glue
Dogan, 2023 Suturing was not required because of tight adherence to PLL Watertight manner + fibrin glue
Moon, 2010 Suturing was not required because of tight adherence to PLL Watertight manner + fibrin glue
Negwer, 2020 Inlay-outlay fibrin sealant patch Running Gore-Tex suture
Alam, 2025 Ventral dura was preserved Watertight suture using interrupted 6-0 prolene + dural sealant in selective cases
Komaitis, 2025 Patched with TachoSil Watertight suture using interrupted 5-0 prolene and patched with TachoSil

Dorsal dural closure was consistently performed in a watertight fashion, most commonly using running or interrupted sutures (eg, Prolene or Gore-Tex), frequently augmented with fibrin sealants or patch materials. Despite variability in technique, the overall CSF leak rate remained low (4.1%), with only one case requiring reoperation.

Complications

Across the seven included studies,5-11 postoperative complications were infrequent and predominantly transient (Table 5). Transient neurological deterioration was reported in 7 patients (9.5%), most commonly in the Negwer series (4/12), 7 where all cases resolved prior to discharge. Two additional transient deficits were described by Alam et al (1/30) 10 and Komaitis et al (1/7), 11 both of which fully recovered.

Table 5.

Summary of Complications

Study n Transient neuro Permanent neuro CSF leak Reoperation Other complications Notes
Coppes 2012 6 13 1 0 1 1 1 superficial infection CSF leak required re-exploration
Negwer 2020 7 12 4 0 0 0 2 UTI All neurological deterioration resolved before discharge
Dogan 2023 8 7 0 0 0 0 None reported No neurological or CSF complications
Bocchetti 2017 9 2 0 0 0 0 None reported Preliminary 2- case series; ventral dura preserved
Alam 2025 10 30 1 0 2 0 None reported All CSF leaks treated conservatively
Komaitis 2025 11 7 1 1 0 1 None reported Pt 4 persistent deficit after intraop MEP loss; Pt 5 transient deficit after hypotension → negative re- exploration, full recovery
Moon 2010 5 3 0 0 0 0 None reported No intraoperative monitoring used

Persistent neurological deterioration was reported in a single patient (1.4% of the total cohort), occurring in the Komaitis series following intraoperative neuromonitoring signal loss. 11

Cerebrospinal fluid (CSF) leakage occurred in three patients overall (4.1%). Two cases were reported in the prospective cohort by Alam et al. 10 (6.7%) and were managed conservatively without reoperation. One case was reported by Coppes et al. 6 (7.7%) and required surgical re-exploration. No CSF leaks were observed in the remaining studies.

Reoperation was required in two patients (2.7%): one for persistent CSF leakage 6 and one for postoperative neurological deterioration with negative surgical exploration. 11 Other reported complications included two urinary tract infections 7 and one superficial wound infection. 6 No mortality was reported in any study.

Within the limitations of small case series and short follow-up in several studies, permanent neurological morbidity and reoperation rates were low.

Operative Metrics

Operative metrics varied considerably across studies (Table 6). Operative time reporting varied across studies, with some reporting mean values and others median values. Mean operative time ranged from 124 ± 17 minutes in the prospective cohort by Alam et al. 10 to 241 minutes (range 217-263) in the transpedicular–transdural series by Komaitis et al. 11 Among studies reporting median values, operative duration ranged from 152 minutes (range 83-289) 7 to 210 minutes (range 140-360). 6 Estimated blood loss was inconsistently reported; where available, it ranged from a mean of 143 ± 40 mL 10 to 385 mL. 11 Length of hospital stay also demonstrated variability, ranging from 3 days in the Dogan series 8 to a median of 10 days in the Negwer cohort. 7 Several early case series did not report operative time, blood loss, or length of stay.

Table 6.

Summary of Operative Metrics

Study n Operative time Blood loss Hospital stay Notes
Moon, 2010 5 3 NR NR NR Mobilized POD 3
Coppes, 2012 6 13 Median 210 min (140-360) NR Median 6 d (4-20) —
Negwer, 2020 7 12 Median 152 min (83-289) NR Median 10 d (3-18) Giant calcified discs
Dogan, 2023 8 7 NR NR 3 d All discharged POD3
Bocchetti, 2017 9 2 NR NR 7-10 d Preliminary series
Alam, 2025 10 30 124 ± 17 min 143 ± 40 mL 4.2 ± 1.1 d Prospective cohort
Komaitis, 2025 11 7 Mean 241 min (217-263) Mean 385 mL (280-520) NR Instrumented transpedicular approach

Discussion

Thoracic disc herniation (TDH) causing myelopathy remains a surgically challenging entity due to the narrow thoracic canal, kyphotic alignment, and frequent ventral or calcified disc morphology. The optimal surgical approach remains debated, with options including transthoracic, thoracoscopic, transpedicular, costotransversectomy, transfacet pedicle-sparing, and transdural posterior techniques. This systematic review specifically evaluated outcomes of the posterior transdural approach in 74 patients across seven Level IV series5-11 and demonstrates three principal findings: (1) neurological improvement or stability was achieved in the majority of cases; (2) permanent neurological deterioration was rare; and (3) overall complication and reoperation rates were low despite a high proportion of calcified or giant disc pathology.

Interpretation of Neurological Outcomes

Across studies reporting extractable patient-level data, neurological improvement was observed in approximately three-quarters of patients, with only one case of persistent deterioration in the pooled cohort. 11 Importantly, the majority of included cases involved centrally located and frequently calcified discs, a pathology typically considered technically demanding. This suggests that direct ventral decompression through a transdural corridor can achieve satisfactory cord decompression without the morbidity traditionally associated with anterior access.

The favorable neurological profile observed in this review aligns with larger posterolateral and transfacet pedicle-sparing series, which report neurological improvement rates between 60-80% with low permanent deficit rates. 12 However, those series often include mixed soft and calcified discs and employ indirect or lateralized decompression techniques rather than direct intradural ventral exposure. The transdural approach differs conceptually by providing direct visualization of ventral pathology without thoracotomy, potentially reducing manipulation of the spinal cord during ventral disc removal.

In comparison, anterior and transthoracic approaches historically offer excellent ventral exposure but at the cost of approach-related morbidity, including pulmonary complications, chest tube requirements, and longer recovery. 1 Systematic comparisons between anterior and posterior strategies suggest that posterior-based approaches may carry lower systemic morbidity while achieving comparable neurological recovery. 1 Our findings support this trend, particularly in centrally located calcified discs where posterior transdural decompression avoids thoracotomy.

Calcified and Giant Discs: Complexity vs Prognosis

A notable feature of the included cohorts is the high proportion of calcified and giant discs. Calcified morphology is frequently associated with dural adherence, intradural extension, and greater operative complexity. In a comparative cohort of soft vs calcified TDH, 13 calcified discs were associated with significantly higher blood loss and increased intraoperative neuromonitoring alerts, although long-term neurological outcomes were comparable between groups. This pattern is consistent with the broader literature: disc consistency appears to influence surgical complexity rather than ultimate neurological prognosis. 13

Within the transdural series included in this review, transient neurological worsening was more frequently reported in cohorts composed entirely of giant calcified discs. However, persistent deterioration remained rare. This suggests that while calcified morphology increases intraoperative risk, careful microsurgical technique and neuromonitoring can mitigate permanent injury. These findings contrast with earlier historical laminectomy-only series, where cord manipulation without direct disc removal was associated with high paralysis and mortality rates. 14 Modern microsurgical techniques, magnification, and neuromonitoring likely account for the improved safety profile seen in contemporary series.

Complication Profile in Context

The pooled CSF leak rate in this review was approximately 4%, with only one case requiring reoperation. This rate compares favorably with reports of posterolateral and costotransversectomy approaches, where CSF leak and wound complications are not uncommon.2,15 Transthoracic and thoracoscopic series report approach-specific pulmonary and cardiopulmonary complications in up to 15-20% of cases.1,16 Notably, the transdural approach shifts risk from pulmonary morbidity to dural management; however, modern watertight closure techniques appear to limit clinically significant CSF-related sequelae.

Reoperation rates across the pooled cohort were low (approximately 3%). This is comparable to, and in some series lower than, rates reported following costotransversectomy or transthoracic discectomy.1,2 Importantly, no mortality was reported in the transdural cohorts, whereas historical laminectomy-only strategies in elderly calcified discs demonstrated nontrivial mortality in medically complex patients. 14

Operative Metrics and Surgical Trade-Offs

Operative time and blood loss varied substantially between series. Instrumented or giant-disc cohorts demonstrated longer operative duration and higher blood loss, reflecting underlying pathology rather than approach-specific inefficiency. Compared with published transthoracic series, which often report prolonged operative times and higher systemic morbidity, the transdural approach may offer a less physiologically demanding alternative in selected patients. However, direct comparisons remain limited by heterogeneity in patient selection and reporting.

Selection Bias and Approach-specific Indications

It is critical to emphasize that transdural approaches are typically selected for centrally located, ventral, or calcified pathology where standard posterolateral exposure may be insufficient. Therefore, outcomes reported in these series likely reflect highly selected cases managed in experienced centers. The absence of comparative controlled trials prevents definitive conclusions regarding superiority over alternative approaches. Rather, the data suggest that the transdural technique represents a viable posterior strategy in appropriately selected patients, particularly when anterior access is undesirable.

Limitations

This review is limited by the exclusively Level IV nature of the included studies, small sample sizes, and retrospective design. Neurological outcomes were assessed using heterogeneous scoring systems (mJOA, Frankel, ASIA, qualitative assessment), necessitating harmonization into simplified categories of improvement, stability, or deterioration. Follow-up duration varied substantially across studies, limiting direct comparison of long-term recovery trajectories. Subgroup analysis by disc consistency, giant morphology, or fixation status was not feasible due to inconsistent reporting and limited stratified data. Publication bias and underreporting of minor complications remain possible. Additionally, no formal meta-analysis was performed due to methodological heterogeneity and low event rates; therefore, the findings should be interpreted descriptively.

Clinical Implications

Despite these limitations, the available evidence suggests that posterior transdural decompression for thoracic myelopathy can achieve favorable neurological outcomes with low permanent morbidity, even in predominantly calcified or giant disc pathology. When compared with anterior or thoracoscopic strategies, the transdural approach may avoid thoracotomy-related systemic complications while providing direct ventral decompression. The choice of approach should remain individualized, guided by disc morphology, surgeon expertise, and patient comorbidity profile.

Future multicenter prospective studies with standardized neurological scoring and direct comparative cohorts are required to better define the relative merits of transdural vs alternative posterior and anterior techniques.

Conclusion

The posterior transdural approach for thoracic disc herniation causing myelopathy demonstrates favorable neurological outcomes with a low rate of permanent morbidity across predominantly calcified and giant disc pathology. Despite technical complexity and the need for dural opening, pooled data from available case series suggest that direct ventral decompression via a transdural corridor can be performed safely in experienced hands. Complication and reoperation rates were low, and persistent neurological deterioration was uncommon.

Supplemental Material

Supplemental material - Posterior Transdural Decompression for Thoracic Disc Herniation Causing Myelopathy: A Systematic Review of Outcomes and Safety

Supplemental material for Posterior Transdural Decompression for Thoracic Disc Herniation Causing Myelopathy: A Systematic Review of Outcomes and Safety by Hussein Akil, MD, Deya AlWady, MD, Rodrigo Muscogliati, MD, Mohammad Badra, MD, Rami Abou Faour, MD, Spyridon Komaitis, MD, Khalid M. Salem, MD, Zeinab Nahle, MD, Farwa Abbas, Elie Najjar, MD in Global Spine Journal

Funding: The authors received no financial support for the research, authorship, and/or publication of this article.

The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Supplemental Material: Supplemental material for this article is available online.

ORCID iDs

Hussein Akil https://orcid.org/0009-0006-2110-6164

Deya AlWady https://orcid.org/0009-0009-8165-7859

Rodrigo Muscogliati https://orcid.org/0009-0005-9667-787X

Mohammad Badra https://orcid.org/0000-0002-2018-3022

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Supplementary Materials

Supplemental material - Posterior Transdural Decompression for Thoracic Disc Herniation Causing Myelopathy: A Systematic Review of Outcomes and Safety

Supplemental material for Posterior Transdural Decompression for Thoracic Disc Herniation Causing Myelopathy: A Systematic Review of Outcomes and Safety by Hussein Akil, MD, Deya AlWady, MD, Rodrigo Muscogliati, MD, Mohammad Badra, MD, Rami Abou Faour, MD, Spyridon Komaitis, MD, Khalid M. Salem, MD, Zeinab Nahle, MD, Farwa Abbas, Elie Najjar, MD in Global Spine Journal


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