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. 1980 Apr;30(1):199–204. doi: 10.1016/S0006-3495(80)85089-2

A model for the effects of potential and external K+ concentration on the Cs+ blocking of inward rectification.

S Ciani, S Krasne, S Hagiwara
PMCID: PMC1328725  PMID: 7260268

Abstract

Inward rectification in starfish egg cell membranes is blocked by external Cs+, the degree of blocking being an increasing function of hyperpolarizing potentials and of the external concentration of K+. While the effect of K+ and the particular functional dependence of blocking on potential are difficult to reconcile with a one-ion pore model, both features can be accounted for assuming that the pore has at least two sites and tat a considerable fraction of the blocked pores is simultaneously occupied by a Cs+ ion in the inner site and by a K+ in the outer one.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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