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Italian Journal of Pediatrics logoLink to Italian Journal of Pediatrics
. 2026 May 5;52:107. doi: 10.1186/s13052-026-02256-z

Global burden and time trends of vaccine-preventable diseases in children and adolescents

Xingyi Jin 1, Rui Wang 1, Siying Tu 1, Chunyan Yuan 2,4, Fei Ge 2, Yong Liu 2, Shaokang Wang 1,5,✉, Ying Ma 3,✉, Guiju Sun 1
PMCID: PMC13289554  PMID: 42087201

Abstract

Background

Vaccine-preventable diseases (VPDs) are a major global health concern for children and adolescents. The COVID-19 pandemic further complicated VPDs prevention by halting vaccinations in many areas. This study aimed to analyze the global burden and trends of eight high - burden VPDs in 0 – 19 - year - olds from 1990 to 2021.

Methods

Using data from the Global Burden of Disease 2021 database across 204 countries, incidence and DALYs were stratified by age, sex, and SDI. A linear regression model calculated AAPCs, and a joinpoint regression model identified a significant trend - change years. The SII and CII quantified SDI-related burden inequality.

Results

From 1990 to 2021, global VPDs incidence and DALYs decreased. However, in 2021, there were still a large number of cases and DALYs. Hepatitis E DALYs rose, especially in males and infants. Males generally had a higher incidence of most VPDs. Lower SDI regions had heavier burdens, except for varicella and herpes zoster in high-SDI areas. The COVID-19 pandemic increased the incidence of some VPDs.

Conclusions

Despite progress in VPDs control, gaps in vaccination, socioeconomic inequalities, and new threats like hepatitis E remain. Targeted actions such as perinatal immunization, hepatitis E vaccination in endemic areas, and restoring pandemic-affected health systems are needed to achieve global health equity.

Keywords: Vaccine-preventable diseases, Global burden of disease, Children and adolescents, Incidence, DALYs

Introduction

Vaccines, the most cost-effective public health intervention of modern medicine, have succeeded in averting millions of premature deaths due to infectious diseases over the past half-century. Over the past 50 years, the Essential Programme on Immunization (EPI) has saved about 154 million lives. Vaccinations have also contributed to improved infant survival rates globally and reduced the mortality rate among children in low- and middle-income countries by half [1].

In addition, the economic benefits of vaccines cannot be ignored. Vaccination is not only effective in preventing disease, but also delivers a health return of $54 for every $1 invested [1]. Reports from the World Health Organization (WHO) show that vaccinating against 23 vaccine-preventable diseases (VPDs) could cut the need for antibiotics around the world by 22% per year. This would help the fight against antimicrobial resistance and generate substantial cost savings [2]. However, some of these vaccines are not utilized properly. There are still big differences in the number of people 0–19 years old who have been vaccinated around the world, and an estimated 14.5 million children did not receive any vaccines in 2023 [3]. This means that diseases like measles, which can be prevented, are still a threat to children’s health.

The current global immunization system is facing three problems: first, the COVID-19 pandemic disrupted routine vaccination services, which can indirectly exacerbate antimicrobial resistance by increasing the incidence of treatable infections. Second, vaccine hesitancy and antimicrobial drug resistance have been named by the WHO as two of the top 10 threats to global health; and third, vaccination rates have not yet rebounded to pre-pandemic levels in 2019. Additionally, climate change is altering the transmission dynamics of infectious diseases. For example, over the past 10 years, dengue fever has caused eight times as many illnesses in the tropics [3–5].

In this context, our study focused on the eight VPDs with the highest incidence in the global pediatric and adolescent population in 2021: acute hepatitis A, varicella and herpes zoster, acute hepatitis E, pertussis, acute hepatitis B, typhoid fever, measles, and meningitis. These diseases are associated with considerable morbidity and potential for serious complications. For example, varicella and herpes zoster, which result from the reactivation of the varicella-zoster virus, can lead to debilitating conditions such as postherpetic neuralgia [6]. Meanwhile, the number of children vaccinated against diphtheria-tetanus-pertussis (DTP) has stagnated, with the number of unvaccinated increasing to 14.5 million in 2023 [7]. Measles outbreaks have begun in 103 countries worldwide. These outbreaks affect populations that collectively account for approximately three-quarters of all infants globally. Low vaccine coverage (80% or less) was a major factor. In contrast, 91 countries with high measles vaccine coverage had no outbreaks [7]. Similarly, vaccination rates for these VPDs remain significantly lower in many low- and middle-income countries, exacerbating the disease burden in these regions.

Against this backdrop of persistent coverage gaps, compounded by pandemic-related disruptions, vaccine hesitancy, and the evolving challenges of antimicrobial resistance and climate change, a detailed and updated assessment of the VPD landscape among children and adolescents is urgently needed. However, recent comprehensive analyses that simultaneously examine the burden, long-term trends, and socioeconomic inequalities across multiple high-burden VPDs in this age group are lacking. Therefore, this study aims to fill this gap by utilizing data from the Global Burden of Disease (GBD) 2021 study [8] to: (1) quantify the current incidence and DALYs of eight high-burden VPDs among individuals aged 0–19 years globally and across key strata (age, sex, SDI); (2) analyze their temporal trends from 1990 to 2021; and (3) assess socioeconomic inequalities in this burden. The findings are intended to identify persistent gaps and inform targeted strategies to accelerate progress towards equitable VPD control and related Sustainable Development Goals.

Methodologies and materials

Overview

The estimates for incidence and DALYs attributable to VPDs in the 0–19-year-old population were obtained from the GBD 2021 database. Data were extracted using the GBD Results Tool (available at: https://ghdx.healthdata.org/gbd-results-tool), which provides access to the standardized, modelled estimates generated by the GBD collaboration. According to WHO definitions, children and adolescents were defined as aged 0 to 19 years and were further categorized into 5 age subgroups: (1) less than 1 year old, (2) 2 to 4 years old, (3) 5 to 9 years old, (4) 10 to 14 years old, and (5) 15 to 19 years old [9].

Sociodemographic Index (SDI) serves as a comprehensive measure of a country’s or region’s socio-economic development. This index encompasses various dimensions, including but not limited to the economic structure and size, educational attainment, living standards, and social welfare and security. The index values range from 0 to 1, with higher values indicating greater socio-economic development. According to the GBD database, countries and regions are categorized into five classes based on their SDI: low, low-middle, middle, middle-high, and high.

The design and methodology of the GBD studies have been comprehensively documented in the existing GBD literature [8]. This study followed the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guidelines.

Based on factors including population incidence, data quality, and surveillance limitations, this study focused on eight VPDs: acute hepatitis A, varicella and herpes zoster, acute hepatitis E, acute hepatitis B, pertussis, typhoid fever, measles, and meningitis. These diseases were selected after a detailed analysis of the GBD database for the year 2021 in conjunction with the WHO report. Of the 13 vaccine-preventable infectious diseases listed in the GBD database, the incidence rates in 2021 for people aged 0–19, in descending order, are as follows: acute hepatitis A (4,763.70 per 100,000 population), varicella and herpes zoster (2,481.70 per 100,000 population), acute hepatitis E (483.60 per 100,000), acute hepatitis B (358.13 per 100,000), pertussis (268.69 per 100,000), typhoid fever (189.05 per 100,000), measles (189.05 per 100,000), and other diseases. The following are the most common diseases: diarrhea, measles (180.57 per 100,000), meningitis (54.59 per 100,000), yellow fever (1.92 per 100,000), tetanus (0.90 per 100,000), diphtheria (0.44 per 100,000), rabies (0.15 per 100,000) and cervical cancer (0.11 per 100,000). Starting with yellow fever, the incidence of these diseases declined significantly. Disease selection was based on two primary criteria: (1) high incidence rates within the 0–19-year-old population globally in 2021, and (2) significant public health relevance as evidenced by their inclusion in major immunization programs or WHO priority disease lists.

The diseases in this study followed the standard WHO definitions. GBD 2021 integrates International Classification of Diseases (ICD) codes with disease burden analysis results to provide burden estimates for eight VPDs (https://ghdx.healthdata.org/record/ihme-data/gbd-2021-cause-icd-code-mappings). The ICD-10 codes are as follows: acute hepatitis A(B15–B15.9), varicella and herpes zoster(B01–B02.9), acute hepatitis E(B17.2), acute hepatitis B(B16–B16.9, B17.0, B18.0-B18.1, B19.1-B19.11), pertussis(A37–A37.91), typhoid fever(A01.0-A01.09), measles(B05–B05.9), meningitis(A39–A39.9, A87–A87.9, D86.81, G00–G03.9, G06–G09.9).

Statistical analysis

This study used incidence and DALYs estimated annual percentage change (EAPC) in prevalence to quantify the global burden of VPDs. Annual percent change (APC) and its 95% confidence intervals (CI) were computed using the joinpoint regression model to assess internal trends over each independent time period. The average estimated annual percentage change (EAPC) and its CI were calculated using a log-transformed linear regression model to analyze temporal trends in VPDs incidence and DALYs from 1990 to 2021. Fitted curves were utilized to analyze the relationship between disease burden indicators and the SDI. Pearson’s correlation coefficient was used to evaluate the relationship between VPDs and different SDI regions. In addition, to explore the influences of EAPC, we evaluated the association between EAPC and VPDs (2021) and the SDI (2021) separately at the national level.

Slope index of inequality (SII) and concentration index (CII) were used to quantify socioeconomic inequities in the burden of VPDs across countries, as measured by the SDI. SII was calculated by regression of the country-level prevalence due to VDPs loss in all age populations on the sociodemographic development-related relative position scale, defined by the midpoint of the cumulative class range of the population ranked by SDI. CII was calculated by fitting a Lorenz concentration curve to the observed cumulative relative distribution of the populations ranked by SDI and the prevalence of disease, as well as numerically integrating the area under the curve. All statistical analyses and visualisations in this study were performed using R language version 4.3.3, with a significance level of p < 0.05.

GBD modelling assumptions

The estimates produced by GBD 2021 rely on several key methodological principles: (1) the use of all available eligible data from censuses, surveys, vital registration, disease registries, and scientific literature; (2) a standardized, Bayesian meta-regression framework (DisMod-MR 2.1) and other cause-specific models to synthesize data, address biases, and estimate rates for every location-year even in the presence of data sparsity; (3) the correction of case data for under-reporting and misclassification where possible; and (4) the coherent estimation of incidence, prevalence, and mortality such that these metrics are internally consistent. A comprehensive description of these models, data processing steps, and uncertainty propagation is provided in the GBD 2021 capstone methodology paper and cause-specific publications [8, 10].

Result

Diseases with very low incidence rates (e.g., yellow fever, tetanus, diphtheria, rabies, cervical cancer) were not analyzed in detail as stratified estimates by age, sex, and SDI were unstable or unavailable, limiting meaningful comparative analysis. Therefore, the results of the following eight VPDs were included: acute hepatitis A, varicella and herpes zoster, acute hepatitis E, pertussis, acute hepatitis B, typhoid fever, measles, and meningitis.

Global trends

In 2021, the global burden of VPDs among individuals under 20 years remained high, with 231,427,150 estimated new cases (95% UI: 213,068,912 to 252,452,755). This corresponds to an incidence rate of 8,780.03 per 100,000 population (95% UI: 8,083.52 to 9,577.69) (Table 1; Fig. 1). In 2021, the global number of DALYs attributable to these eight diseases was 72,850,844 (95% UI: 17,348,230 to 43,927,979), with an overall DALY rate of 1,081.57 per 100,000 population (95% UI: 658.16 to 1,704.54).

Table 1.

Incidence, disability-adjusted life-years (DALYs), and Estimated annual percentage changes (EAPCs) for vaccine preventable diseases (VPDs) among children and adolescents from 1990 to 2021 at the global level, stratified by sex, age, and sociodemographic index (SDI)

Location Incidence DALYs
1990 2021 EAPCs, 2019–2021 EAPCs, 1990–2021 1990 2021 EAPCs, 2019–2021 EAPCs, 1990–2021
Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI)
Overall

92,972,252.9426222

(114944684.27771,

76148117.8540194)

15,194.43(12087.47,19956.84)

231,427,150.26

(213068912.48,

252452754.78)

8780.03(8083.52,9577.69) −12.62(−57.40,79.25) −2.67(−4.19,−1.12)

130,274,887.71

(68553491.00,

231179630.22)

5768.01(3035.25,10235.64)

28,508,441.17

(17348229.67,

43927979.18)

1081.57(658.16,1704.54) −14.20(−60.87,88.14) −3.15(−5.39,−0.85)
acute hepatitis A
Global

132,219,138.79

(124369519.51,

141636079.11)

5854.10(5506.55,6271.04)

125,563,617.13

(118596854.14,

132931558.35)

4763.70(4499.39,5043.23) −1.02(−2.51,0.50) −0.59(−0.65,−0.53) 4,521,917.68(3621823.40,5365456.02) 200.21(160.36,237.56)

1,121,482.66

(717955.53,

1905085.85)

42.55(27.24,72.28) −11.41(−20.99,−0.66) −4.18(−4.92,−3.44)
SEX
Male

66,076,129.15

(62050891.41,

70761021.15)

5709.13(5361.34,6113.92)

64,712,630.91

(61079811.69,

68631677.32)

4763.55(4496.14,5052.04) −0.93(−1.30,−0.55) −0.52(−0.58,−0.47)

2,008,963.64

(1598543.29,

2444163.15)

173.58(138.12,211.18)

604,289.97

(293315.88,

1112491.89)

44.48(21.59,81.89) −9.32(−14.54,−3.79) −3.74(−4.42,−3.05)
Female

66,143,009.65

(62243200.64,

70875057.96)

6006.46(5652.31,6436.18)

60,850,986.22

(57524127.89,

64335343.20)

4763.86(4503.41,5036.64) −1.11(−3.78,1.63) −0.67(−0.74,−0.59)

2,512,954.05

(1836700.93,

3094081.80)

228.20(166.79,280.97)

517,192.69

(319908.20,

812695.27)

40.49(25.04,63.62) −13.67(−36.56,17.46) −4.59(−5.39,−3.79)
Age
<1 year

29,659,645.44

(25017628.92,

35259742.85)

23,217.38

(19583.64,

27601.10)

19,856,103.46

(16665634.16,

23681336.89)

15,672.43

(13154.19,

18691.68)

−1.84(−10.45,7.60) −1.20(−1.38,−1.01)

1,599,147.93

(1188699.61,

1928293.94)

1251.80(930.51,1509.46)

338,989.85

(173672.83,

659099.23)

267.56(137.08,520.23) −15.52(−41.63,22.27) −3.98(−4.71,−3.25)
2–4 years

37,831,652.69

(35485649.41,

39704490.70)

10,292.30(9654.06,10801.82)

36,100,122.84

(32859882.74,

38957584.80)

8956.37(8152.47,9665.30) 0.09(−2.11,2.34) −0.45(−0.49,−0.42)

1,130,078.05

(840633.14,

1435800.97)

307.44(228.70,390.62)

211,228.70

(117965.54,

367940.90)

52.41(29.27,91.29) −8.42(−21.31,6.59) −5.12(−5.97,−4.26)
5–9 years

24,663,228.99

(23293625.45,

25837852.25)

4226.55(3991.84,4427.85)

28,486,500.47

(27769954.06,

29016461.54)

4146.18(4041.89,4223.32) 0.04(−0.79,0.87) −0.14(−0.20,−0.09) 611,264.63(475895.97,752771.33) 104.75(81.55,129.00)

162,902.52

(109745.55,

252738.20)

23.71(15.97,36.79) −12.25(−32.99,14.91) −4.07(−4.97,−3.15)
10–14 years

13,633,724.73

(11890405.58,

15494259.14)

2545.11(2219.67,2892.43)

16,126,100.04

(15026061.70,

16844099.59)

2419.03(2254.01,2526.73) 0.27(−1.68,2.26) −0.25(−0.33,−0.17) 405,703.99(320754.34,493007.76) 75.74(59.88,92.03)

186,879.49

(133555.04,

278798.56)

28.03(20.03,41.82) −7.89(−10.95,−4.72) −2.66(−3.29,−2.03)
15–19 years 9,708,991.34(8069939.10,11641903.13) 1869.19(1553.63,2241.31)

10,309,996.76

(9333759.29,

11109464.89)

1652.30(1495.84,1780.42) 0.24(−2.61,3.17) −0.51(−0.61,−0.41)

290,988.05

(235933.71,

356801.72)

56.02(45.42,68.69)

130,465.86

(90775.35,

193480.32)

20.91(14.55,31.01) −2.38(−14.18,11.04) −3.07(−3.56,−2.57)
SDI
High SDI

5,680,834.66

(5117411.79,

6255577.78)

2260.40(2036.21,2489.09)

4,863,616.16

(4311595.81,

5410653.30)

2089.88(1852.67,2324.93) −0.4682 −0.15(−0.23,−0.07) 15,910.44(12101.24,20930.79) 6.33(4.82,8.33) 7238.68(4698.13,10715.94) 3.11(2.02,4.60) −0.47(−1.37,0.44) −1.94(−2.26,−1.63)
High−middle SDI

16,429,424.29

(15260531.34,

17583613.68)

4438.40(4122.62,4750.20)

11,364,902.70

(10256047.95,

12333979.64)

3746.31(3380.79,4065.76) −1.23632 −0.41(−0.54,−0.27)

140,083.81

(107881.55,

172960.71)

37.84(29.14,46.73)

19,011.33

(13174.79,

27437.26)

6.27(4.34,9.04) −1.24(−2.36,−0.10) −5.79(−6.12,−5.47)
Middle SDI

42,152,581.58

(39656024.20,

44872439.85)

5513.36(5186.82,5869.10)

32,845,375.63

(30632059.53,

35002004.52)

4384.11(4088.68,4671.97) −1.05924 −0.63(−0.76,−0.50)

1,022,357.52

(818962.58,

1209923.58)

133.72(107.12,158.25)

125,668.85

(79180.16,

218991.69)

16.77(10.57,29.23) −1.06(−1.36,−0.76) −6.20(−6.37,−6.03)
Low−middle SDI

44,611,056.08

(41124261.25,

48539959.47)

7548.10(6958.14,8212.86)

40,508,019.97

(38300857.41,

42947686.90)

5299.41(5010.66,5618.57) −1.4987 −1.03(−1.16,−0.90)

2,343,907.85

(1850145.28,

2871187.05)

396.58(313.04,485.80)

615,132.63

(366649.02,

1152244.21)

80.47(47.97,150.74) −1.50(−4.11,1.18) −4.26(−5.06,−3.45)
Low SDI

23,255,585.86

(21612219.92,

24999172.89)

8318.15(7730.35,8941.81)

35,890,788.19

(33957234.78,

38000353.52)

6143.52(5812.55,6504.62) −0.87008 −1.10(−1.22,−0.98) 998,762.97(738373.71,1268215.95) 357.24(264.10,453.62) 354,101.24(230392.87,553042.94) 60.61(39.44,94.67) −0.87(−3.21,1.52) −5.16(−5.95,−4.35)
varicella and herpes zoster
Global

61,880,769.26

(59720590.46,

63794834.56)

2739.82(2644.17,2824.56)

65,413,599.06

(63228478.89,

67592619.02)

2481.70(2398.80,2564.37) −1.72(−2.20,−1.24) −0.09(−0.18,−0.01) 801,783.82(683699.27,949219.50) 35.50(30.27,42.03)

529,582.15

(425268.53,

641724.45)

20.09(16.13,24.35) −4.44(−7.45,−1.33) −1.57(−1.67,−1.47)
SEX
Male

31,729,711.12

(30483284.83,

32759273.75)

2741.52

(2633.83,

2830.48)

33,655,280.99

(32443148.03,

34795857.55)

2477.39(2388.17,2561.35) −1.70(−2.12,−1.28) −0.10(−0.19,−0.02)

413,414.26

(354207.28,

486440.70)

35.72(30.60,42.03)

271,751.31

(217828.27,

334062.94)

20.00(16.03,24.59) −4.33(−7.30,−1.27) −1.61(−1.70,−1.51)
Female

30,151,058.14

(29161351.82,

31050905.63)

2738.02(2648.15,2819.74)

31,758,318.07

(30772639.25,

32787762.66)

2486.27(2409.11,2566.87) −1.74(−2.27,−1.21) −0.08(−0.16,0.01)

388,369.56

(325292.41,

464624.63)

35.27(29.54,42.19) 257,830.84(208264.23,309332.14) 20.18(16.30,24.22) −4.55(−7.61,−1.39) −1.53(−1.63,−1.43)
Age
<1 year

22,707,765.13

(16324995.25,

29710103.96)

17,775.49(12779.10,23256.88)

21,715,385.92

(15593851.24,

28438508.92)

17,139.96(12308.23,22446.52) −0.05(−1.29,1.21) −0.08(−0.10,−0.06)

306,137.68

(264106.92,

362107.88)

239.64(206.74,283.46)

193,679.42

(148355.62,

245603.32)

152.87(117.10,193.85) −2.62(−5.36,0.20) −1.46(−1.54,−1.39)
2–4 years

17,301,348.12

(11208982.88,

25096349.75)

4706.92(3049.46,6827.59)

19,237,290.61

(12637428.46,

27938304.74)

4772.73(3135.32,6931.44) −0.04(−2.92,2.92) 0.06(0.04,0.09)

157,106.31

(126937.62,

198099.67)

42.74(34.53,53.89)

97,537.27

(72125.94,

126090.89)

24.20(17.89,31.28) −3.81(−7.57,0.10) −1.68(−1.79,−1.57)
5–9 years

6,001,437.16

(3257232.67,

9392774.37)

1028.47(558.19,1609.65)

7,202,028.94

(3867198.85,

11267016.61)

1048.25(562.87,1639.90) −0.34(−2.60,1.98) −0.07(−0.15,−0.00) 123,038.18(100020.40,149390.45) 21.09(17.14,25.60) 84,894.18(70572.79,102327.90) 12.36(10.27,14.89) −4.11(−6.30,−1.86) −1.53(−1.68,−1.39)
10–14 years 1,884,525.42(950567.03,3574198.91) 351.80(177.45,667.22)

2,450,904.76

(1205871.50,

4520507.49)

367.65(180.89,678.11) −0.18(−0.99,0.65) −0.07(−0.17,0.02)

41,386.96

(34875.62,

48737.99)

7.73(6.51,9.10) 33,440.17(27726.96,40638.15) 5.02(4.16,6.10) −2.79(−3.81,−1.77) −1.26(−1.33,−1.18)
15–19 years

1,226,870.75

(706124.74,

2036411.63)

236.20(135.94,392.05)

1,581,977.26

(875047.07,

2675344.54)

253.53(140.24,428.75) −0.04(−2.42,2.40) 0.06(−0.03,0.14) 26,185.52(21866.44,32424.44) 5.04(4.21,6.24) 22,292.56(17696.82,29227.73) 3.57(2.84,4.68) −1.57(−2.91,−0.21) −1.10(−1.14,−1.05)
SDI
High SDI

6,308,527.61

(6141786.21,

6495058.85)

2510.16(2443.81,2584.38)

5,484,337.08

(5311454.58,

5672666.44)

2356.60(2282.31,2437.52) −1.14(−1.50,−0.77) −0.05(−0.13,0.04) 16,140.38(14195.44,18754.43) 6.42(5.65,7.46) 7489.32(6038.87,9546.98) 3.22(2.59,4.10) −1.60(−3.68,0.54) −2.09(−2.39,−1.79)
High−middle SDI

9,244,486.91

(8990946.13,

9561777.46)

2497.39(2428.90,2583.11)

6,869,460.57

(6526839.43,

7242328.46)

2264.44(2151.50,2387.35) −4.34(−6.48,−2.16) 0.36(0.10,0.63) 58,441.34(50225.03,68510.50) 15.79(13.57,18.51) 12,776.19(10805.76,15191.97) 4.21(3.56,5.01) −4.64(−6.57,−2.67) −4.05(−4.21,−3.89)
Middle SDI

19,719,944.57

(18912615.48,

20420801.66)

2579.28(2473.68,2670.94)

17,188,303.53

(16416412.18,

17958052.76)

2294.25(2191.22,2396.99) −2.81(−4.37,−1.22) −0.06(−0.21,0.09) 205,910.48(183194.69,232997.35) 26.93(23.96,30.47) 65,285.92(54887.25,76965.62) 8.71(7.33,10.27) −5.33(−5.76,−4.90) −3.39(−3.53,−3.26)
Low−middle SDI

17,122,993.23

(16326483.64,

17722867.02)

2897.17(2762.41,2998.67)

19,012,034.82

(18274162.27,

19581311.06)

2487.22(2390.69,2561.70) −1.01(−1.10,−0.93) −0.38(−0.41,−0.34) 288,763.15(235980.99,346094.21) 48.86(39.93,58.56) 182,286.41(149550.39,219995.84) 23.85(19.56,28.78) −4.94(−5.32,−4.55) −2.11(−2.21,−2.01)
Low SDI

9,434,472.93

(9103743.77,

9714585.90)

3374.56(3256.26,3474.75)

16,809,017.59

(16363885.82,

17206143.08)

2877.24(2801.05,2945.22) −0.63(−0.95,−0.32) −0.51(−0.57,−0.45)

231,955.50

(181542.68,

299574.21)

82.97(64.93,107.15) 261,263.88(195710.78,329368.02) 44.72(33.50,56.38) −4.87(−11.18,1.89) −1.77(−1.86,−1.68)
acute hepatitis E
Global

11,194,967.36

(8754133.40,

14135793.04)

495.67(387.60,625.87)

12,746,798.20

(9906793.01,

16239504.32)

483.60(375.85,616.10) −0.01(−0.60,0.58) −0.12(−0.15,−0.10)

126,576.93

(46512.93,

234575.57)

5.60(2.06,10.39)

137,635.38

(63461.33,

243810.03)

5.22(2.41,9.25) −7.30(−24.01,13.08) 0.25(0.02,0.48)
SEX
Male

5,795,510.04

(4536984.54,

7325154.20)

500.75(392.01,632.91)

6,649,824.14

(5161736.78,

8481596.58)

489.50(379.96,624.34) −0.09(−1.30,1.13) −0.12(−0.15,−0.09) 64,722.81(15823.87,177645.17) 5.59(1.37,15.35) 81,240.53(24666.31,150883.54) 5.98(1.82,11.11) −4.64(−6.39,−2.86) 0.54(0.36,0.73)
Female

5,399,457.32

(4222650.36,

6817853.14)

490.33(383.46,619.13)

6,096,974.07

(4750075.20,

7758242.26)

477.32(371.87,607.37) 0.08(−2.46,2.68) −0.13(−0.15,−0.10)

61,854.12

(16809.40,

172122.81)

5.62(1.53,15.63) 56,394.85(14558.65,125348.23) 4.42(1.14,9.81) −10.77(−42.51,38.48) −0.10(−0.40,0.20)
Age
<1 year

468,936.60

(304950.06,

699173.08)

367.08(238.71,547.31)

446,194.75

(287816.75,

665485.79)

352.18(227.17,525.27) −0.59(−1.54,0.37) −0.03(−0.07,0.01) 67,335.75(18021.69,134398.70) 52.71(14.11,105.21) 67,369.48(25199.81,124096.29) 53.17(19.89,97.95) −9.38(−38.26,33.01) 0.47(0.23,0.70)
2–4 years

1,971,562.23

(1282061.20,

2799471.45)

536.37(348.79,761.61)

2,125,166.54

(1389666.67,

3006804.18)

527.25(344.77,745.98) −0.25(−1.88,1.40) 0.02(−0.02,0.06) 11,134.85(1941.90,33805.50) 3.03(0.53,9.20) 9897.61(3095.65,19846.69) 2.46(0.77,4.92) −3.05(−17.22,13.53) −0.75(−0.89,−0.60)
5–9 years

3,722,840.31

(2499824.23,

5216075.85)

637.99(428.40,893.88)

4,347,034.81

(2943730.86,

6171607.43)

632.71(428.46,898.27) 0.11(−0.57,0.80) −0.05(−0.07,−0.03) 12,152.46(5907.46,22457.46) 2.08(1.01,3.85) 13,565.52(6993.63,22256.61) 1.97(1.02,3.24) −6.29(−21.44,11.80) 0.35(−0.04,0.74)
10–14 years

2,626,086.71

(1581497.66,

4055790.80)

490.23(295.23,757.13)

3,208,721.17

(1936346.51,

5051698.31)

481.33(290.47,757.79) −0.09(−0.77,0.59) −0.17(−0.24,−0.09) 12,731.43(6757.53,20076.21) 2.38(1.26,3.75)

18,633.44

(10204.76,

33341.52)

2.80(1.53,5.00) −2.97(−7.12,1.35) 0.83(0.62,1.03)
15–19 years

1,921,675.51

(1232366.10,

2778862.73)

369.96(237.26,534.99)

2,138,408.94

(1382499.80,

3060800.04)

342.70(221.56,490.53) 0.17(−3.08,3.54) −0.33(−0.39,−0.27)

12,591.09

(7684.73,

19264.87)

2.42(1.48,3.71) 15,531.46(9238.93,27383.06) 2.49(1.48,4.39) 0.62(−0.13,1.37) −0.01(−0.13,0.10)
SDI
High SDI

573,539.56

(443444.99,

735717.45)

228.21(176.45,292.74)

487,365.26

(374919.12,

633186.68)

209.42(161.10,272.08) 0.15(−2.17,2.52) −0.34(−0.41,−0.27) 1615.55(1075.14,2230.90) 0.64(0.43,0.89) 790.87(557.48,1162.02) 0.34(0.24,0.50) −1.46(−4.42,1.60) −2.03(−2.38,−1.67)
High−middle SDI

1,733,259.09

(1365288.22,

2174519.90)

468.24(368.83,587.44)

1,336,525.56

(1040008.37,

1713857.39)

440.57(342.83,564.95) 0.70(0.49,0.91) −0.41(−0.50,−0.31) 9972.80(4566.65,14244.30) 2.69(1.23,3.85) 3216.39(2004.05,4879.45) 1.06(0.66,1.61) −3.48(−3.67,−3.28) −2.88(−3.06,−2.69)
Middle SDI

3,979,054.20

(3106518.24,

5042774.83)

520.44(406.32,659.57)

3,672,867.01

(2838166.58,

4709518.86)

490.24(378.83,628.61) 0.18(−1.09,1.46) −0.27(−0.36,−0.19) 36,185.97(17910.37,62385.68) 4.73(2.34,8.16) 32,906.45(17372.60,54214.99) 4.39(2.32,7.24) −8.16(−18.98,4.09) 0.56(0.23,0.88)
Low−middle SDI

3,373,681.51

(2642266.72,

4251272.64)

570.82(447.07,719.31)

4,185,472.08

(3295318.73,

5287414.28)

547.56(431.11,691.72) −0.34(−0.35,−0.32) −0.16(−0.22,−0.09) 43,737.46(15442.90,101484.79) 7.40(2.61,17.17)

65,967.35

(26478.10,

125845.37)

8.63(3.46,16.46) −7.78(−30.84,22.98) 1.10(0.79,1.42)
Low SDI

1,527,707.28

(1192795.29,

1955235.76)

546.44(426.64,699.36)

3,056,972.13

(2357553.05,

3909977.73)

523.27(403.55,669.28) −0.35(−1.73,1.05) −0.11(−0.14,−0.09) 35,020.84(6782.12,91271.73) 12.53(2.43,32.65) 34,723.92(13017.44,62490.35) 5.94(2.23,10.70) −6.30(−16.30,4.90) −2.53(−2.77,−2.28)
pertussis
Global

31,776,782.88

(24234235.06,

40469256.02)

1406.94(1072.99,1791.81)

7,082,164.21

(5025544.12,

10038839.40)

268.69(190.66,380.86) −40.73(−74.31,36.73) −2.67(−3.39,−1.94)

23,114,984.91

(10420343.26,

48510037.12)

1023.43(461.37,2147.82)

4,556,396.34

(2052140.26,

9124986.01)

172.86(77.86,346.19) −38.36(−83.89,135.85) −3.28(−4.00,−2.56)
SEX
Male

14,793,674.96

(11282323.80,

18840148.88)

1278.21(974.82,1627.83)

3,291,315.61

(2333336.35,

4669817.45)

242.28(171.76,343.75) −40.73(−74.59,38.26) −2.70(−3.41,−1.97)

10,813,099.20

(4771386.55,

22902440.13)

934.28(412.26,1978.82)

2,226,020.94

(1023922.41,

4414940.96)

163.86(75.37,324.99) −37.25(−81.90,117.49) −3.24(−3.93,−2.54)
Female

16,983,107.92

(12951911.27,

21629107.14)

1542.24(1176.17,1964.14)

3,790,848.60

(2692207.77,

5360101.76)

296.78(210.77,419.63) −40.73(−74.06,35.42) −2.64(−3.36,−1.92)

12,301,885.71

(5650609.85,

25806164.39)

1117.14(513.13,2343.46)

2,330,375.40

(1030698.88,

4605406.09)

182.44(80.69,360.55) −39.37(−85.52,153.94) −3.33(−4.07,−2.58)
Age
<1 year 12,299,142.80(9379424.14,15663951.99) 9627.69(7342.15,12261.64)

2,659,313.79

(1894014.58,

3747320.69)

2099.00(1494.95,2957.76) −39.18(−73.64,40.32) −2.57(−3.23,−1.90)

9,381,225.86

(4152707.04,

20181178.73)

7343.56(3250.71,15797.70)

1,791,020.15

(767626.82,

3509799.48)

1413.65(605.89,2770.29) −37.70(−85.38,165.47) −3.14(−3.83,−2.45)
2–4 years

6,956,932.44

(5305742.59,

8859870.00)

1892.67(1443.46,2410.37)

1,574,577.28

(1115908.10,

2234807.28)

390.65(276.85,554.45) −40.01(−73.73,36.99) −2.56(−3.26,−1.85)

5,322,383.34

(2335213.90,

11232238.75)

1447.98(635.31,3055.79)

1,080,746.85

(475601.61,

2175227.26)

268.13(118.00,539.67) −35.42(−81.55,126.12) −3.30(−3.96,−2.63)
5–9 years

3,623,964.55

(2763902.07,

4615182.68)

621.04(473.65,790.91)

852,714.28

(599548.65,

1214924.09)

124.11(87.26,176.83) −40.92(−73.02,29.33) −2.49(−3.21,−1.76)

2,435,558.97

(1088708.78,

5355910.57)

417.38(186.57,917.85)

460,500.98

(202699.91,

884164.74)

67.03(29.50,128.69) −40.64(−82.94,106.52) −3.26(−4.06,−2.46)
10–14 years

732,098.81

(558398.07,

932221.29)

136.67(104.24,174.02)

184,070.09

(128480.79,

263909.87)

27.61(19.27,39.59) −40.95(−73.83,33.26) −2.41(−3.13,−1.68)

496,570.18

(212383.49,

1117178.77)

92.70(39.65,208.55) 99,991.90(41359.91,206174.93) 15.00(6.20,30.93) −40.60(−86.33,158.17) −3.21(−4.00,−2.42)
15–19 years 142,992.73(109279.21,182032.85) 27.53(21.04,35.05) 35,863.55(24588.00,52084.26) 5.75(3.94,8.35) −40.97(−74.15,34.83) −2.43(−3.13,−1.73) 98,817.08(40920.15,227950.84) 19.02(7.88,43.89) 20,141.73(8101.71,42765.32) 3.23(1.30,6.85) −38.50(−86.12,172.48) −3.37(−4.07,−2.67)
SDI
High SDI

1,093,301.58

(846200.31,

1389667.86)

435.02(336.70,552.95)

64,364.83

(39428.39,

107353.38)

27.66(16.94,46.13) −68.08(−99.90,10296.13) −3.70(−5.05,−2.32)

90,725.67

(34150.40,

176874.93)

603.02(247.19,1305.43)

3141.11

(1050.94,

7358.55)

46.50(19.19,93.36) −53.23(−93.75,249.71) −6.85(−7.67,−6.02)
High−middle SDI

2,860,408.66

(2214169.27,

3636919.67)

772.74(598.16,982.51)

123,176.97

(82419.61,

174735.90)

40.60(27.17,57.60) −62.81(−98.38,753.14) −4.17(−5.40,−2.93)

860,813.24

(293336.66,

2019858.18)

232.55(79.24,545.66)

34,827.57

(11847.67,

73463.22)

11.48(3.91,24.22) −43.47(−69.19,3.70) −7.14(−7.76,−6.52)
Middle SDI

8,431,867.86

(6486275.81,

10710191.58)

1102.85(848.37,1400.84)

1,007,217.41

(652455.31,

1548840.61)

134.44(87.09,206.74) −53.81(−70.71,−27.14) −2.57(−3.60,−1.53)

4,610,397.11

(1889890.67,

9980733.72)

1575.52(608.50,3690.45)

348,385.28

(143770.92,

699452.89)

170.25(64.51,376.11) −49.11(−77.15,13.36) −4.61(−5.55,−3.66)
Low−middle SDI

11,875,210.74

(8992061.29,

15107160.48)

2009.26(1521.44,2556.10)

2,259,713.01

(1458410.74,

3471563.54)

295.62(190.79,454.16) −38.40(−88.38,226.53) −3.68(−4.39,−2.96)

9,311,692.68

(3596406.80,

21811414.78)

36.10(13.59,70.38)

1,301,350.41

(493140.72,

2874961.33)

1.35(0.45,3.16) −38.75(−87.99,212.24) −4.56(−5.31,−3.80)
Low SDI

7,494,953.13

(5666723.31,

9502984.81)

2680.83(2026.90,3399.07)

3,625,764.39

(2660978.89,

5035843.97)

620.63(455.49,862.00) −32.97(−82.73,160.10) −3.02(−3.63,−2.41)

8,225,572.28

(3633164.96,

16831556.47)

2942.16(1299.53,6020.38)

2,866,876.60

(1176277.68,

5676333.82)

490.73(201.35,971.63) −36.89(−82.89,132.75) −3.77(−4.42,−3.12)
acute hepatitis B
Global

26,255,680.72

(20652223.14,

32448364.45)

1162.49(914.39,1436.67)

9,439,749.66

(7414215.27,

11886378.19)

358.13(281.28,450.95) −2.66(−3.70,−1.61) −3.88(−4.23,−3.53)

1,288,988.00

(649903.11,

1998207.29)

57.07(28.77,88.47)

749,145.51

(519650.11,

980880.39)

28.42(19.71,37.21) −8.05(−20.95,6.94) −1.92(−2.12,−1.72)
SEX
Male

15,257,112.90

(11965631.99,

19561949.14)

1318.25(1033.86,1690.20)

5,556,712.26

(4151545.28,

7003816.55)

409.03(305.60,515.56) −2.65(−3.74,−1.55) −3.86(−4.22,−3.50) 574,153.90(288738.29,913158.74) 49.61(24.95,78.90)

393,480.74

(242249.60,

594089.12)

28.96(17.83,43.73) −5.41(−6.82,−3.98) −1.52(−1.71,−1.34)
Female

10,998,567.82

(8196814.33,

14489556.25)

998.78(744.35,1315.80)

3,883,037.41

(2959073.94,

5138693.48)

303.99(231.66,402.29) −2.67(−3.63,−1.70) −3.90(−4.24,−3.57) 714,834.10(327982.74,1153321.79) 64.91(29.78,104.73) 355,664.77(248352.40,542590.48) 27.84(19.44,42.48) −10.74(−35.33,23.21) −2.28(−2.52,−2.03)
Age
<1 year

2,061,011.34

(1508072.72,

2636227.34)

1613.35(1180.51,2063.62)

602,881.22

(455308.42,

759618.22)

475.85(359.38,599.57) 5.66(−4.92,17.42) −4.93(−5.23,−4.62) 641,451.02(292775.00,1043738.67) 502.12(229.18,817.03)

356,846.30

(244502.51,

492756.81)

281.66(192.99,388.93) −9.31(−36.43,29.38) −1.52(−1.66,−1.39)
2–4 years 3,317,660.77(2101445.84,4806786.89) 902.59(571.71,1307.71)

970,400.75

(625698.98,

1390295.94)

240.75(155.23,344.93) 6.86(−18.03,39.30) −5.15(−5.41,−4.89)

227,255.05

(93767.58,

381436.32)

61.83(25.51,103.77) 79,666.98(54268.35,109088.69) 19.77(13.46,27.06) −4.93(−20.63,13.87) −4.19(−4.69,−3.69)
5–9 years

5,399,033.69

(3707052.84,

7634171.33)

925.24(635.28,1308.27)

1,580,401.05

(1123726.86,

2228829.97)

230.03(163.56,324.40) −3.73(−14.63,8.55) −4.86(−5.23,−4.48) 95,037.65(57344.95,142416.09) 16.29(9.83,24.41) 56,896.39(40041.67,75672.90) 8.28(5.83,11.01) −8.78(−23.19,8.34) −1.65(−2.16,−1.14)
10–14 years

6,051,292.08

(4139895.08,

8503796.68)

1129.64(772.83,1587.47)

2,222,405.32

(1521584.48,

3153283.89)

333.38(228.25,473.01) −5.66(−24.25,17.47) −3.87(−4.39,−3.35) 86,962.28(57355.51,126817.83) 16.23(10.71,23.67) 83,184.84(56736.07,110589.32) 12.48(8.51,16.59) −7.06(−13.74,0.13) −0.34(−0.67,−0.01)
15–19 years 7,601,880.50(5087982.66,11146102.10) 1463.52(979.54,2145.86)

3,550,353.53

(2365075.15,

5272453.79)

568.99(379.03,844.97) −5.24(−8.09,−2.31) −2.64(−3.07,−2.20)

113,805.12

(81697.07,

149074.08)

21.91(15.73,28.70)

112,087.82

(74386.25,

147454.86)

17.96(11.92,23.63) 0.14(−7.04,7.88) −0.67(−0.90,−0.44)
SDI
High SDI

1,196,831.18

(975886.49,

1448089.00)

476.22(388.30,576.19)

209,293.27

(166326.19,

266716.58)

89.93(71.47,114.61) −6.41(−34.60,33.92) −5.35(−5.49,−5.21) 8597.84(5892.22,12231.74) 3.42(2.34,4.87) 737.87(598.39,911.65) 0.32(0.26,0.39) −5.90(−7.10,−4.69) −7.85(−8.31,−7.38)
High−middle SDI

4,394,321.70

(3474844.94,

5536375.60)

1187.12(938.73,1495.65)

274,375.05

(213809.99,

351653.18)

90.44(70.48,115.92) −4.01(−26.38,25.14) −8.65(−9.75,−7.54)

98,831.43

(70995.60,

132934.79)

26.70(19.18,35.91) 10,369.45(7109.61,15336.31) 3.42(2.34,5.06) −7.07(−10.87,−3.11) −6.38(−6.64,−6.11)
Middle SDI

10,266,932.00

(8161310.58,

12869908.81)

1342.87(1067.46,1683.32)

1,833,083.59

(1428446.51,

2341178.33)

244.68(190.67,312.49) −2.61(−6.73,1.69) −5.59(−6.07,−5.11)

421,666.55

(278735.11,

611309.43)

55.15(36.46,79.96)

149,239.28

(86201.26,

232293.86)

19.92(11.51,31.01) −9.14(−20.31,3.60) −2.43(−2.90,−1.96)
Low−middle SDI

5,824,702.29

(4560116.45,

7312350.39)

985.53(771.56,1237.23)

2,509,472.68

(1956004.71,

3190367.95)

328.30(255.89,417.38) −5.67(−7.26,−4.06) −3.36(−3.74,−2.99) 298,014.82(147203.99,550225.86) 50.42(24.91,93.10) 307,971.03(187099.53,443716.34) 40.29(24.48,58.05) −8.61(−31.45,21.83) −0.08(−0.41,0.25)
Low SDI

4,556,810.81

(3556794.30,

5676284.09)

1629.90(1272.21,2030.32)

4,606,831.13

(3627633.16,

5729866.91)

788.56(620.95,980.80) −1.56(−3.47,0.38) −2.45(−2.76,−2.14)

461,559.01

(161137.63,

785395.49)

165.09(57.64,280.92)

280,669.17

(189524.23,

399152.05)

48.04(32.44,68.32) −7.57(−8.55,−6.58) −4.30(−4.75,−3.86)
typhoid fever
Global

14,757,433.12

(10933996.26,

19472954.81)

653.40(484.11,862.18)

4,982,996.09

(3509379.63,

6698319.70)

189.05(133.14,254.12) −4.70(−5.02,−4.38) −4.06(−4.32,−3.79)

12,933,488.82

(6358555.83,

22333343.57)

572.64(281.53,988.82)

5,861,753.75

(2924820.63,

10097163.40)

222.39(110.96,383.07) −7.42(−10.06,−4.72) −2.89(−3.08,−2.70)
SEX
Male

8,059,106.37

(5950106.00,

10653496.71)

696.33(514.10,920.49)

2,797,485.30

(1979987.84,

3760162.31)

205.93(145.75,276.79) −4.69(−5.02,−4.36) −4.00(−4.28,−3.72)

6,899,964.69

(3387873.60,

11854535.53)

596.17(292.72,1024.26)

3,164,635.48

(1570109.98,

5491623.75)

232.95(115.58,404.24) −6.48(−12.63,0.10) −2.91(−3.09,−2.74)
Female

6,698,326.75

(4916771.21,

8928220.51)

608.28(446.49,810.77)

2,185,510.79

(1551666.11,

2936085.16)

171.10(121.48,229.86) −4.71(−5.03,−4.40) −4.13(−4.38,−3.88)

6,033,524.13

(2970841.11,

10478808.04)

547.91(269.78,951.58)

2,697,118.28

(1334594.65,

4681885.12)

211.15(104.48,366.53) −8.49(−20.50,5.33) −2.86(−3.08,−2.65)
Age
<1 year

1,203,170.31

(837061.75,

1534717.40)

941.83(655.25,1201.37)

404,700.77

(247093.93,

598789.80)

319.43(195.03,472.62) −2.76(−3.87,−1.65) −3.90(−4.23,−3.58)

1,307,226.86

(577096.82,

2523597.91)

1023.29(451.75,1975.46) 696,246.89(272225.82,1455033.39) 549.55(214.87,1148.46) −8.11(−32.93,25.90) −2.08(−2.28,−1.89)
2–4 years

3,971,597.72

(2675273.19,

5420842.42)

1080.49(727.82,1474.77)

1,287,368.55

(829048.71,

1842367.68)

319.39(205.69,457.09) −3.68(−6.84,−0.41) −4.13(−4.48,−3.78)

4,004,150.98

(1941882.00,

7302506.07)

1089.35(528.30,1986.69) 1,695,984.98(772840.49,2959138.06) 420.77(191.74,734.16) −5.24(−11.24,1.17) −3.13(−3.30,−2.95)
5–9 years

3,891,313.54

(2480819.34,

5769822.29)

666.86(425.14,988.78)

1,243,736.01

(784955.32,

1839632.60)

181.02(114.25,267.76) −5.31(−5.75,−4.87) −4.16(−4.49,−3.84)

3,095,055.55

(1504038.59,

5762929.81)

530.40(257.75,987.60)

1,181,522.93

(556154.71,

2144873.78)

171.97(80.95,312.18) −10.37(−24.51,6.41) −3.20(−3.63,−2.77)
10–14 years

2,379,794.91

(1434659.45,

3624808.21)

444.25(267.82,676.67) 860,101.83(536825.01,1314788.93) 129.02(80.53,197.23) −4.79(−5.34,−4.25) −3.91(−4.16,−3.66)

1,795,808.95

(829464.49,

3127402.38)

335.24(154.84,583.82)

839,012.93

(392271.05,

1538512.44)

125.86(58.84,230.79) −7.77(−10.88,−4.56) −2.87(−3.12,−2.62)
15–19 years

1,252,497.05

(656879.73,

1965330.66)

241.13(126.46,378.37) 490,294.79(257883.35,781275.94) 78.58(41.33,125.21) −4.27(−5.04,−3.50) −3.67(−3.81,−3.53) 884,222.73(358756.01,1726243.53) 170.23(69.07,332.34) 450,529.60(184841.97,903996.22) 72.20(29.62,144.88) −3.56(−13.47,7.50) −2.66(−2.88,−2.44)
SDI
High SDI 17,132.98(12066.30,24094.03) 6.82(4.80,9.59) 4503.06(3246.53,6058.12) 1.93(1.40,2.60) −3.49(−4.28,−2.68) −3.79(−4.02,−3.56) 11,867.68(3954.54,27665.27) 4.72(1.57,11.01) 2304.08(755.56,5492.36) 0.99(0.32,2.36) −8.44(−35.91,30.79) −4.58(−4.78,−4.39)
High−middle SDI

255,876.05

(185238.09,

345848.70)

69.12(50.04,93.43) 89,669.29(64314.21,118492.18) 29.56(21.20,39.06) −5.09(−5.21,−4.98) −2.54(−2.83,−2.25) 221,388.97(104800.41,394212.66) 59.81(28.31,106.50)

70,753.74

(35756.91,

122938.82)

23.32(11.79,40.53) −10.66(−28.96,12.35) −2.38(−2.84,−1.91)
Middle SDI

2,788,321.50

(2072804.03,

3664604.90)

364.70(271.11,479.31) 892,061.72(630019.24,1196722.01) 119.07(84.09,159.74) −4.75(−5.04,−4.46) −3.54(−3.75,−3.34) 2,379,803.15(1196824.34,4042875.66) 311.27(156.54,528.79)

899,478.71

(449763.57,

1550395.57)

120.06(60.03,206.94) −8.88(−14.18,−3.25) −2.74(−2.93,−2.54)
Low−middle SDI

8,762,194.50

(6477051.25,

11704843.27)

1482.55(1095.90,1980.44)

2,633,083.51

(1861501.13,

3531878.04)

344.47(243.53,462.05) −4.86(−4.90,−4.81) −4.82(−5.09,−4.56)

7,431,062.97

(3713940.46,

12533344.76)

1257.32(628.39,2120.62)

3,088,909.67

(1571368.19,

5212640.98)

404.10(205.57,681.94) −8.05(−15.10,−0.41) −3.57(−3.75,−3.38)
Low SDI

2,927,827.69

(2138345.26,

3859572.22)

1047.24(764.85,1380.51)

1,361,186.89

(963826.14,

1827228.22)

233.00(164.98,312.77) −4.80(−5.14,−4.46) −4.94(−5.13,−4.75)

2,883,660.98

(1351089.66,

5307733.12)

1031.44(483.26,1898.49)

1,797,171.43

(816883.68,

3314596.69)

307.63(139.83,567.37) −5.94(−14.52,3.52) −3.82(−3.92,−3.71)
measles
Global

62,087,466.81

(21921838.14,

135130901.73)

2748.97(970.60,5983.02) 4,759,421.16(4189082.17,5376013.35) 180.57(158.93,203.96) −35.22(−42.12,−27.49) −6.80(−7.78,−5.81)

58,581,088.94

(21863110.63,

117684915.66)

2593.72(968.00,5210.58) 4,839,654.44(2792705.27,7500361.47) 183.61(105.95,284.55) −23.25(−46.04,9.17) −8.02(−8.60,−7.43)
SEX
Male

31,314,713.90

(11073841.98,

67341697.80)

2705.66(956.81,5818.48)

2,394,022.02

(2105315.05,

2706306.22)

176.23(154.97,199.21) −35.32(−42.10,−27.75) −6.81(−7.80,−5.82)

29,482,835.55

(10778976.15,

59288994.35)

2547.39(931.33,5122.71) 2,612,287.71(1499674.51,4083243.31) 192.29(110.39,300.57) −22.10(−46.70,13.86) −7.90(−8.46,−7.34)
Female

30,772,752.91

(10847996.15,

67789203.93)

2794.48(985.11,6155.95)

2,365,399.13

(2081837.26,

2671168.68)

185.18(162.98,209.12) −35.11(−42.15,−27.22) −6.79(−7.77,−5.81)

29,098,253.39

(10617095.37,

57245486.90)

2642.42(964.14,5198.47) 2,227,366.73(1253206.63,3481651.72) 174.37(98.11,272.57) −24.54(−45.18,3.88) −8.15(−8.76,−7.53)
Age
<1 year

15,250,951.39

(5464812.23,

31075025.31)

11,938.35(4277.82,24325.33)

1,167,884.70

(1026275.33,

1321867.39)

921.81(810.04,1043.35) −32.93(−39.56,−25.57) −6.73(−7.67,−5.78)

14,527,523.72

(5454536.53,

29541127.31)

11,372.05(4269.78,23124.60) 1,295,797.14(748185.51,2048984.67) 1022.77(590.54,1617.26) −20.90(−46.40,16.74) −7.61(−8.20,−7.01)
2–4 years

18,839,300.96

(6612033.34,

41818417.88)

5125.33(1798.84,11376.92) 1,441,547.24(1269077.97,1628034.19) 357.65(314.86,403.91) −34.54(−40.25,−28.28) −6.74(−7.77,−5.70)

19,279,875.61

(6943462.35,

39333295.49)

5245.19(1889.01,10700.83) 1,582,826.24(877907.78,2538972.86) 392.70(217.81,629.91) −20.91(−47.26,18.60) −8.09(−8.73,−7.46)
5–9 years

6,631,490.46

(2330637.38,

14712655.75)

1136.44(399.40,2521.32) 510,020.08(449654.40,575581.57) 74.23(65.45,83.78) −36.65(−47.10,−24.14) −6.57(−7.65,−5.48)

5,612,431.97

(2064922.54,

11376676.95)

961.81(353.87,1949.63) 441,494.47(269633.35,687280.79) 64.26(39.24,100.03) −26.20(−32.36,−19.49) −7.90(−8.61,−7.17)
10–14 years

1,546,726.35

(545332.87,

3427240.18)

288.74(101.80,639.79) 125,224.60(110263.28,141371.29) 18.78(16.54,21.21) −37.60(−48.89,−23.81) −6.40(−7.47,−5.32)

1,327,056.33

(453111.62,

2966003.65)

247.73(84.59,553.69) 109,708.72(63390.90,181591.07) 16.46(9.51,27.24) −26.54(−40.78,−8.88) −7.83(−8.47,−7.20)
15–19 years

526,032.79

(186428.08,

1163592.75)

101.27(35.89,224.02) 43,889.40(38579.30,49630.33) 7.03(6.18,7.95) −38.33(−50.77,−22.76) −6.30(−7.36,−5.24)

457,228.28

(148727.86,

1059147.49)

88.03(28.63,203.91) 39,451.94(21344.65,71510.91) 6.32(3.42,11.46) −24.53(−53.31,21.99) −7.95(−8.57,−7.32)
SDI
High SDI

800,350.54

(478613.05,

1414862.71)

318.46(190.44,562.97) 2288.52(1228.35,3729.19) 0.98(0.53,1.60) −73.89(−95.80,62.50) −12.90(−14.38,−11.39) 87,820.67(34198.64,178036.64) 34.94(13.61,70.84) 177.15(79.91,342.25) 0.08(0.03,0.15) −57.99(−63.62,−51.49) −15.16(−16.91,−13.37)
High−middle SDI

2,204,878.12

(833113.45,

4744091.07)

595.65(225.06,1281.61) 29,664.06(23588.32,35889.13) 9.78(7.78,11.83) −77.51(−99.81,2596.09) −6.14(−7.99,−4.25) 719,340.82(255831.33,1437384.58) 194.33(69.11,388.31) 4202.47(2020.42,10102.34) 1.39(0.67,3.33) −68.85(−99.00,874.82) −10.27(−11.71,−8.81)
Middle SDI

13,872,963.96

(4979430.77,

30274609.98)

1814.52(651.29,3959.78)

348,113.26

(287072.82,

413324.72)

46.47(38.32,55.17) −58.04(−91.86,116.23) −6.84(−8.35,−5.31)

4,903,288.28

(1832546.24,

9770334.37)

641.33(239.69,1277.91)

49,894.42

(28549.56,

82191.60)

6.66(3.81,10.97) −59.81(−85.56,11.84) −9.80(−11.11,−8.47)
Low−middle SDI

28,009,642.80

(9694192.85,

61372843.60)

4739.17(1640.24,10384.16)

1,256,324.90

(1040171.59,

1492539.36)

164.36(136.08,195.26) −37.32(−62.70,5.34) −8.26(−9.57,−6.93)

21,588,806.61

(7897701.23,

43105962.85)

3652.78(1336.27,7293.44)

458,703.02

(270959.79,

710467.92)

60.01(35.45,92.95) −36.54(−57.68,−4.83) −10.99(−12.07,−9.91)
Low SDI

17,165,711.40

(5923433.96,

37309545.15)

6139.90(2118.72,13345.03)

3,120,567.76

(2727109.07,

3572898.17)

534.16(466.81,611.58) −25.65(−43.36,−2.41) −7.36(−8.04,−6.68)

31,255,194.01

(11020474.99,

63175796.12)

11,179.49(3941.85,22596.98)

4,324,210.53

(2433827.37,

6779754.15)

740.19(416.60,1160.51) −20.76(−48.71,22.41) −8.75(−9.32,−8.16)
meningitis
Global

3,004,827.94

(2418042.88,

3651840.48)

133.04(107.06,161.69)

1,438,804.75

(1198565.25,

1689522.45)

54.59(45.47,64.10) −1.87(−2.84,−0.89) −2.93(−3.22,−2.65)

28,906,058.61

(24909542.57,

34103875.49)

1279.84(1102.89,1509.97)

10,712,790.94

(7852228.01,

14434967.58)

406.43(297.90,547.64) −7.06(−11.51,−2.40) −3.36(−3.70,−3.03)
SEX
Male

1,632,304.84

(1313384.11,

1982888.40)

141.03(113.48,171.33) 786,425.26(657599.18,923729.45) 57.89(48.41,68.00) −1.50(−3.42,0.46) −2.95(−3.22,−2.68)

15,711,786.68

(13127437.83,

18628703.85)

1357.53(1134.24,1609.56)

5,868,181.55

(4062519.12,

8343949.74)

431.96(299.05,614.21) −6.36(−7.25,−5.46) −3.43(−3.74,−3.11)
Female

1,372,523.09

(1104839.28,

1663949.70)

124.64(100.33,151.10) 652,379.48(544137.18,766324.90) 51.07(42.60,59.99) −2.31(−6.64,2.23) −2.91(−3.21,−2.61)

13,194,271.93

(11154815.56,

16116119.19)

1198.17(1012.97,1463.51)

4,844,609.40

(3618632.10,

6415738.94)

379.27(283.29,502.27) −7.89(−16.30,1.37) −3.29(−3.65,−2.93)
Age
<1 year

1,186,495.13

(937834.50,

1451823.94)

928.78(734.13,1136.48)

578,616.95

(478529.20,

690397.28)

456.70(377.70,544.93) −0.41(−6.82,6.44) −2.53(−2.80,−2.26)

12,795,672.89

(11010725.02,

15395609.85)

10,016.37(8619.12,12051.58)

4,676,025.49

(3507522.30,

6221156.22)

3690.79(2768.49,4910.36) −6.56(−20.85,10.32) −3.08(−3.44,−2.72)
2–4 years

695,922.57

(488385.04,

950737.08)

189.33(132.87,258.65)

263,384.83

(189044.53,

352886.22)

65.35(46.90,87.55) −1.53(−10.84,8.75) −3.56(−3.95,−3.16)

7,141,243.18

(5634411.90,

8984303.90)

1942.81(1532.87,2444.23)

2,224,251.82

(1291136.89,

3624879.54)

551.83(320.33,899.33) −5.43(−19.43,11.00) −3.89(−4.31,−3.47)
5–9 years

356,926.78

(243226.60,

510614.17)

61.17(41.68,87.50)

190,952.44

(132649.77,

266805.98)

27.79(19.31,38.83) −0.64(−1.91,0.66) −2.82(−3.18,−2.46) 2,432,676.09(2073664.28,2827121.20) 416.89(355.37,484.49) 1,038,136.72(846402.75,1338187.00) 151.10(123.19,194.77) −6.03(−9.43,−2.49) −3.08(−3.41,−2.76)
10–14 years

186,141.77

(115969.75,

280703.92)

34.75(21.65,52.40) 126,175.74(82780.51,181112.11) 18.93(12.42,27.17) −0.62(−2.24,1.02) −2.18(−2.45,−1.92)

1,272,995.14

(1122400.27,

1421439.97)

237.64(209.53,265.35)

800,779.82

(688577.96,

960159.24)

120.12(103.29,144.03) −3.52(−4.69,−2.34) −2.13(−2.34,−1.92)
15–19 years

138,788.06

(94517.81,

199040.37)

26.72(18.20,38.32) 106,070.29(75008.91,151242.91) 17.00(12.02,24.24) −0.34(−3.73,3.17) −1.83(−2.04,−1.62)

971,775.35

(881118.68,

1072393.32)

187.09(169.63,206.46)

740,574.79

(644099.77,

876053.86)

118.69(103.22,140.40) −0.44(−1.32,0.44) −1.76(−1.96,−1.57)
SDI
High SDI

182,797.82

(141677.61,

225564.39)

49.38(38.27,60.94)

35,671.17

(27357.79,

46367.65)

11.76(9.02,15.28) 0.68(−5.88,7.70) −4.04(−4.25,−3.83)

251,659.10

(241656.56,

264100.33)

100.13(96.15,105.09)

36,732.92

(33615.02,

39798.15)

15.78(14.44,17.10) −7.76(−32.19,25.49) −5.88(−6.11,−5.65)
High−middle SDI

1,021,996.36

(828786.48,

1238941.05)

172.92(140.23,209.63)

437,995.88

(363088.03,

520116.67)

57.30(47.50,68.04) −2.57(−4.17,−0.94) −4.74(−4.85,−4.63)

1,364,568.00

(1178438.19,

1621209.26)

368.64(318.35,437.97)

127,438.19

(110963.12,

147186.40)

42.01(36.58,48.52) −11.00(−25.80,6.75) −6.52(−6.73,−6.31)
Middle SDI

55,230.75

(40281.21,

73491.87)

21.98(16.03,29.24)

16,499.72

(12339.99,

22008.88)

7.09(5.30,9.46) −2.51(−2.63,−2.39) −3.98(−4.20,−3.75)

5,595,476.98

(4949258.14,

6252267.42)

731.86(647.34,817.77)

1,018,732.21

(827969.94,

1235592.78)

135.98(110.52,164.92) −9.59(−22.50,5.46) −4.85(−5.14,−4.56)
Low−middle SDI

1,112,859.11

(902039.05,

1342347.48)

398.05(322.65,480.14)

766,595.11

(645400.35,

899656.23)

131.22(110.47,154.00) −2.52(−8.26,3.58) −3.60(−3.92,−3.27)

9,612,108.80

(8371938.03,

11208910.99)

1626.35(1416.51,1896.52)

3,049,813.48

(2360381.55,

3979191.40)

398.99(308.79,520.57) −9.03(−23.60,8.32) −4.06(−4.45,−3.66)
Low SDI

629,882.55

(500800.81,

771965.88)

82.39(65.50,100.97)

181,077.75

(144014.55,

223578.82)

24.17(19.22,29.84) −2.37(−3.99,−0.72) −3.75(−4.03,−3.47) 12,063,413.42(9970396.31,15065823.39) 4314.89(3566.25,5388.81)

6,473,668.20

(4501869.01,

9482221.07)

1108.11(770.60,1623.10) −6.61(−10.14,−2.93) −4.27(−4.60,−3.94)

Fig. 1.

Fig. 1

Global trends in incidence and DALYs for 8 vaccine-preventable diseases in children and adolescents, 1990–2021

The incidence of acute hepatitis A was the highest at 4,763.70 per 100,000 (95% UI: 4,499.39 to 5,043.23), followed by varicella and herpes zoster at 2,481.70 per 100,000 (95% UI: 2,398.80 to 2,564.37) (Table 1; Fig. 1). This was closely followed by acute hepatitis E at 483.60 (95% UI: 375.85 to 616.10), acute hepatitis B at 358.13 (95%UI: 281.28 to 450.95), pertussis at 268.69 (95% UI: 190.66 to 380.86), typhoid fever at 189.05 (95% UI: 133.14 to 254.12) and measles at 180.57 (95% UI: 158.93 to 203.96). Meningitis was the lowest with 54.59 cases per 100,000 population (95% UI: 45.47 to 64.10). Furthermore, the global DALYs rates for all eight diseases exhibited a downwards trend.

From 1990 to 2021, global VPD incidence and DALYs among individuals under 20 years declined substantially, with EAPCs of −2.67 (95% CI: −4.19 to −1.12) for incidence and −3.15 (95% CI: −5.39 to −0.85) for DALYs (Table 1; Fig. 1). Notably, hepatitis E represented an exception, with DALYs increasing at an EAPC of 0.25 (95% CI: 0.02 to 0.48) from 1990 to 2021, contrasting with declines observed in other VPD. Joinpoint regression further identified distinct temporal phases: hepatitis E exhibited an initial rise during 1990–1995 (annual percent change (APC) = 0.01), followed by an upward and a decline (1995–1999, APC = 0.15, p < 0.001; 1999–2009, APC = −0.36, p < 0.001), and a resurgence post to 2009 (APC = 0.05, p < 0.001) (Fig. 2, Table 2).

Fig. 2.

Fig. 2

Fig. 2

Fig. 2

Fig. 2

Fig. 2

Fig. 2

Fig. 2

Fig. 2

Jointpoint regression of incidence and DALYs for 8 vaccine-preventable diseases in children and adolescents globally, 1990–2021

Table 2.

Joinpoint regression analysis of vaccine-preventable diseases (VPDs) burden among children and adolescents from 1990 to 2019 at the Global level

Cause Measure Year APC(95%CI)
acute hepatitis A Incidence 1990–1992 −0.082(−0.541,0.378) P
acute hepatitis A Incidence 1992–1999 −0.886(−1.008,−0.764) <0.01
acute hepatitis A Incidence 1999–2011 −0.190(−0.252,−0.128) <0.01
acute hepatitis A Incidence 2011–2021 −1.204(−1.265,−1.143) <0.01
acute hepatitis A DALYS 1990–2003 −1.799(−1.955,−1.643) <0.01
acute hepatitis A DALYS 2003–2006 −0.566(−1.516,0.393)
acute hepatitis A DALYS 2006–2012 −3.958(−4.450,−3.464) <0.01
acute hepatitis A DALYS 2012–2021 −11.731(−11.975,−11.486) <0.01
varicella and herpes zoster Incidence 1990–1994 8.547(2.716,14.709) <0.01
varicella and herpes zoster Incidence 1994–2005 −1.307(−2.462,−0.139) <0.01
varicella and herpes zoster Incidence 2005–2013 −6.293(−7.775,−4.788) <0.01
varicella and herpes zoster Incidence 2013–2021 −2.454(−4.295,−0.578) <0.01
varicella and herpes zoster DALYS 1990–1994 6.494(2.101,11.077) <0.01
varicella and herpes zoster DALYS 1994–2005 −1.675(−2.446,−0.897) <0.01
varicella and herpes zoster DALYS 2005–2013 −6.033(−7.389,−4.657) <0.01
varicella and herpes zoster DALYS 2013–2021 −2.909(−4.310,−1.488) <0.01
acute hepatitis E Incidence 1990–1995 0.003(−0.026,0.032)
acute hepatitis E Incidence 1995–1999 0.156(0.101,0.210) <0.01
acute hepatitis E Incidence 1999–2009 −0.357(−0.371,−0.344) <0.01
acute hepatitis E Incidence 2009–2021 0.049(0.039,0.059) <0.01
acute hepatitis E DALYS 1990–2004 0.584(0.482,0.686) <0.01
acute hepatitis E DALYS 2004–2012 1.212(0.948,1.477) <0.01
acute hepatitis E DALYS 2012–2019 −1.759(−2.157,−1.360) <0.01
acute hepatitis E DALYS 2019–2021 −7.222(−8.328,−6.102) <0.01
pertussis Incidence 1990–1994 −4.513(−5.764,−3.246) <0.01
pertussis Incidence 1994–2013 −1.634(−1.821,−1.448) <0.01
pertussis Incidence 2013–2019 −1.250(−2.229,−0.261) <0.01
pertussis Incidence 2019–2021 −40.732(−42.454,−38.959) <0.01
pertussis DALYS 1990–1995 −4.624(−6.136,−3.088) <0.01
pertussis DALYS 1995–2001 −1.274(−2.839,0.316)
pertussis DALYS 2001–2019 −2.458(−2.780,−2.135) <0.01
pertussis DALYS 2019–2021 −38.359(−41.204,−35.376) <0.01
acute hepatitis B Incidence 1990–2001 −1.441(−1.593,−1.288) <0.01
acute hepatitis B Incidence 2001–2011 −4.354(−4.582,−4.125) <0.01
acute hepatitis B Incidence 2011–2019 −6.230(−6.453,−6.006) <0.01
acute hepatitis B Incidence 2019–2021 −2.777(−5.286,−0.201) <0.01
acute hepatitis B DALYS 1990–2000 −0.988(−1.280,−0.695) <0.01
acute hepatitis B DALYS 2000–2013 −1.709(−1.904,−1.513) <0.01
acute hepatitis B DALYS 2013–2019 −3.413(−3.902,−2.923) <0.01
acute hepatitis B DALYS 2019–2021 −7.814(−11.244,−4.252) <0.01
typhoid fever Incidence 1990–1995 −2.213(−2.451,−1.975) <0.01
typhoid fever Incidence 1995–2011 −3.215(−3.274,−3.156) <0.01
typhoid fever Incidence 2011–2014 −9.110(−9.523,−8.696) <0.01
typhoid fever Incidence 2014–2021 −3.744(−3.929,−3.559) <0.01
typhoid fever DALYS 1990–1995 −0.787(−1.495,−0.074) <0.01
typhoid fever DALYS 1995–2009 −2.520(−2.652,−2.388) <0.01
typhoid fever DALYS 2009–2019 −3.927(−4.166,−3.687) <0.01
typhoid fever DALYS 2019–2021 −7.040(−9.969,−4.016) <0.01
measles Incidence 19,990–2001 −1.550(−2.365,−0.728) <0.01
measles Incidence 2001–2011 −6.746(−7.518,−5.967) <0.01
measles Incidence 2011–2019 −9.889(−11.362,−8.392) <0.01
measles Incidence 2019–2021 −35.217(−39.091,−31.096) <0.01
measles DALYS 1990–2001 −2.844(−3.757,−1.922) <0.01
measles DALYS 2001–2009 −11.928(−13.265,−10.572) <0.01
measles DALYS 2009–2011 0.103(−6.669,7.367)
measles DALYS 2011–2021 −11.965(−12.921,−11.001) <0.01
meningitis Incidence 1990–1996 −1.391(−1.698,−1.084) <0.01
meningitis Incidence 1996–2009 −1.901(−2.020,−1.781) <0.01
meningitis Incidence 2009–2017 −5.810(−6.103,−5.517) <0.01
meningitis Incidence 2017–2021 −2.809(−3.313,−2.301) <0.01
meningitis DALYS 1990–1996 −1.738(−2.113,−1.362) <0.01
meningitis DALYS 1996–2008 −2.305(−2.435,−2.174) <0.01
meningitis DALYS 2008–2014 −3.848(−4.215,−3.480) <0.01
meningitis DALYS 2014–2021 −7.031(−7.260,−6.801) <0.01

In the period coinciding with the COVID-19 pandemic (2019–2021), accelerated declines were observed in measles (EAPC = −0.35, 95% CI: −0.42 to −0.27) and pertussis (EAPC = −0.41, 95% CI: −0.74 to 0.37) (Table 1). It was found that the rates of acute hepatitis A (EAPC = −1.02, 95%CI = −2.51 to 0.50), varicella, and herpes zoster (EAPC = −1.72, 95%CI = −2.20 to −1.24) all went down more than they did from 1990 to 2021. However, the rates of acute hepatitis E (EAPC = −0.01, 95%CI:95% CI: −0.60 to 0.58) were less than they were from 1990 to 2021. Acute hepatitis B (EAPC = −1.87, 95% CI: −3.70 to −1.61), and meningitis (EAPC = −2.66, 95% CI: −2.84 to −0.89), the downward trend was smaller than that of the 1990–2021 period. Typhoid fever was almost unaffected. The incidence of pertussis in 1-year-old infants and hepatitis A and B in children aged 2–4 years both showed an inflection point in 2019, trending upward (Fig. 3).

Fig. 3.

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Fig. 3

Jointpoint regression of incidence for 8 vaccine-preventable diseases in children and adolescents globally, by age Group,1990–2021

Gender and age

Sex differences persisted across all VPDs. Males almost consistently experienced higher incidence rates than females, exemplified by typhoid (205.9 vs. 171.1 per 100,000 in 2021; difference: 34.8 per 100,000) (Table 1). DALY patterns mirrored this disparity, except for pertussis, where the female burden slightly exceeded males (182.44 vs. 163.86 per 100,000 in 2021; difference: 18.58 per 100,000) (Fig. 4). Notably, hepatitis E DALYs increased exclusively among males (EAPC = 0.54, 95% CI: 0.36 to 0.73).

Fig. 4.

Fig. 4

Fig. 4

Fig. 4

Fig. 4

Age-sex cross-Section of Global incidence of vaccine-preventable diseases in children and adolescents in 2021

Between 1990 and 2021, the burden of incidence and DALYs varied considerably by different age groups (Fig. 5). The VPDs burden in 2021 was concentrated in the <1 year age group, the 2 to 4 year age group, and the 5 to 9 year age group (Fig. 6). The incidence and DALYs of multiple VPDs are higher in the younger than 1 year age group than in other age groups. The incidence of most VPDs and DALYs progressively decreased with age, but fluctuations may occur in some age groups, such as children aged 2–4 years who still have a higher risk of incidence for some diseases (Fig. 4 in Supplement3). Critical inflection points were identified through joinpoint regression: Acute hepatitis B surged in infants post-2018 (APC = 3.642, 95% CI: 2.08 to 5.22), contrasting with sharp declines in pertussis after 2019 (APC = −38.49, 95% CI: −42.95 to −33.68). Hepatitis E in 2 to 4-year-olds escalated continuously since 2004 (APC = 0.171, 95% CI: 0.148 to 0.193), reaching peak incidence in 2021. Varicella and herpes zoster peaked in 2019 (APC 0.279, 95% CI: 0.127 to 0.431) before declining post-pandemic (APC = −0.153, 95% C:-0.455 to 0.150) (Table 3; Fig. 3).

Fig. 5.

Fig. 5

Fig. 5

Fig. 5

Global trends in incidence and DALYs for 8 vaccine-preventable diseases in children and adolescents, by age group, 1990–2021

Fig. 6.

Fig. 6

Description of Global vaccine preventable disease incidence and DALYs by age and sex group for children and adolescents in 2021

Table 3.

Jointpoint regression of incidence for 8 vaccine−preventable diseases in children and adolescents globally, by age Group,1990–2021

Cause Age Year APC(95%CI) P
acute hepatitis A <1 year 1990–2000 −0.380(−0.488,−0.272) <0.01
acute hepatitis A <1 year 2000–2013 −0.846(−0.940,−0.752) <0.01
acute hepatitis A <1 year 2013–2019 −3.528(−3.789,−3.266) <0.01
acute hepatitis A <1 year 2019–2021 −1.835(−2.618,−1.046) <0.01
acute hepatitis A 2–4 years 1990–1999 −0.506(−0.554,−0.458) <0.01
acute hepatitis A 2–4 years 1999–2005 0.037(−0.053,0.127)
acute hepatitis A 2–4 years 2005–2018 −0.707(−0.732,−0.682) <0.01
acute hepatitis A 2–4 years 2018–2021 0.089(−0.176,0.355)
acute hepatitis A 5–9 years 1990–1992 0.880(−0.543,2.323)
acute hepatitis A 5–9 years 1992–2008 −0.027(−0.135,0.082)
acute hepatitis A 5–9 years 2008–2015 −0.573(−0.950,−0.195) <0.01
acute hepatitis A 5–9 years 2015–2021 0.166(−0.314,0.648)
acute hepatitis A 10–14 years 1990–1992 0.840(−1.612,3.354)
acute hepatitis A 10–14 years 1992–2009 0.048(−0.039,0.134)
acute hepatitis A 10–14 years 2009–2016 −1.070(−1.335,−0.803) <0.01
acute hepatitis A 10–14 years 2016–2021 0.173(−0.377,0.726)
acute hepatitis A 15–19 years 1990–2005 −0.038(−0.097,0.021)
acute hepatitis A 15–19 years 2005–2011 −0.722(−1.064,−0.378) <0.01
acute hepatitis A 15–19 years 2011–2016 −1.735(−1.992,−1.478) <0.01
acute hepatitis A 15–19 years 2016–2021 0.293(−0.053,0.640)
varicella and herpes zoster <1 year 1990–1993 −0.516(−0.606,−0.426) <0.01
varicella and herpes zoster <1 year 1993–2000 −0.102(−0.140,−0.063) <0.01
varicella and herpes zoster <1 year 2000–2004 0.289(0.146,0.433) <0.01
varicella and herpes zoster <1 year 2004–2021 −0.133(−0.142,−0.124) <0.01
varicella and herpes zoster 2–4 years 1990–2002 −0.139(−0.157,−0.121) <0.01
varicella and herpes zoster 2–4 years 2002–2016 0.150(0.137,0.163) <0.01
varicella and herpes zoster 2–4 years 2016–2019 0.279(0.127,0.431) <0.01
varicella and herpes zoster 2–4 years 2019–2021 −0.153(−0.455,0.150)
varicella and herpes zoster 5–9 years 1990–1993 1.454(1.229,1.680) <0.01
varicella and herpes zoster 5–9 years 1993–2001 0.587(0.538,0.636) <0.01
varicella and herpes zoster 5–9 years 2001–2005 −0.994(−1.133,−0.855) <0.01
varicella and herpes zoster 5–9 years 2005–2021 −0.135(−0.150,−0.119) <0.01
varicella and herpes zoster 10–14 years 1990–1994 2.460(2.083,2.840) <0.01
varicella and herpes zoster 10–14 years 1994–2008 −0.293(−0.370,−0.215) <0.01
varicella and herpes zoster 10–14 years 2008–2014 −0.001(−0.370,0.369)
varicella and herpes zoster 10–14 years 2014–2021 −0.422(−0.602,−0.243) <0.01
varicella and herpes zoster 15–19 years 1990–1998 1.389(1.200,1.580) <0.01
varicella and herpes zoster 15–19 years 1998–2005 −0.865(−1.050,−0.679) <0.01
varicella and herpes zoster 15–19 years 2005–2014 0.480(0.292,0.669) <0.01
varicella and herpes zoster 15–19 years 2014–2021 −0.293(−0.480,−0.106) <0.01
acute hepatitis E <1 year 1990–1994 −0.842(−1.084,−0.600) <0.01
acute hepatitis E <1 year 1994–2006 −0.136(−0.182,−0.091) <0.01
acute hepatitis E <1 year 2006–2018 0.216(0.170,0.262) <0.01
acute hepatitis E <1 year 2018–2021 −0.576(−0.818,−0.333) <0.01
acute hepatitis E 2–4 years 1990–1995 −0.810(−0.917,−0.703) <0.01
acute hepatitis E 2–4 years 1995–1999 0.499(0.296,0.703) <0.01
acute hepatitis E 2–4 years 1999–2004 −0.390(−0.533,−0.248) <0.01
acute hepatitis E 2–4 years 2004–2021 0.171(0.148,0.193) <0.01
acute hepatitis E 5–9 years 1990–2000 0.114(0.076,0.151) <0.01
acute hepatitis E 5–9 years 2000–2009 −0.261(−0.304,−0.217) <0.01
acute hepatitis E 5–9 years 2009–2014 0.168(0.061,0.275) <0.01
acute hepatitis E 5–9 years 2014–2021 −0.093(−0.145,−0.041) <0.01
acute hepatitis E 10–14 years 1990–1999 0.610(0.566,0.654) <0.01
acute hepatitis E 10–14 years 1999–2001 −0.320(−0.873,0.237)
acute hepatitis E 10–14 years 2001–2010 −0.628(−0.679,−0.578) <0.01
acute hepatitis E 10–14 years 2010–2021 −0.068(−0.105,−0.030) <0.01
acute hepatitis E 15–19 years 1990–1999 0.610(0.566,0.654) <0.01
acute hepatitis E 15–19 years 1999–2005 −0.320(−0.873,0.237)
acute hepatitis E 15–19 years 2005–2013 −0.628(−0.679,−0.578) <0.01
acute hepatitis E 15–19 years 2013–2021 −0.068(−0.105,−0.030) <0.01
pertussis <1 year 1990–1995 −3.301(−4.524,−2.063) <0.01
pertussis <1 year 1995–2000 −0.691(−2.348,0.995)
pertussis <1 year 2000–2019 −1.928(−2.147,−1.709) <0.01
pertussis <1 year 2019–2021 −38.489(−42.949,−33.679) <0.01
pertussis 2–4 years 1990–1994 −4.104(−5.511,−2.675) <0.01
pertussis 2–4 years 1994–2001 −0.674(−1.547,0.208)
pertussis 2–4 years 2001–2019 −1.880(−2.106,−1.652) <0.01
pertussis 2–4 years 2019–2021 −40.020(−41.971,−38.004) <0.01
pertussis 5–9 years 1990–1996 −4.183(−5.131,−3.226) <0.01
pertussis 5–9 years 1996–2002 −0.518(−1.501,0.476)
pertussis 5–9 years 2002–2019 −1.700(−1.902,−1.497) <0.01
pertussis 5–9 years 2019–2021 −40.943(−42.654,−39.181) <0.01
pertussis 10–14 years 1990–1992 −4.972(−7.490,−2.386) <0.01
pertussis 10–14 years 1992–1998 −3.160(−4.316,−1.990) <0.01
pertussis 10–14 years 1998–2019 −1.177(−1.312,−1.042) <0.01
pertussis 10–14 years 2019–2021 −40.955(−42.519,−39.348) <0.01
pertussis 15–19 years 1990–1995 −3.435(−4.337,−2.523) <0.01
pertussis 15–19 years 1995–2007 −2.142(−2.508,−1.774) <0.01
pertussis 15–19 years 2007–2019 −0.492(−0.818,−0.164) <0.01
pertussis 15–19 years 2019–2021 −41.002(−42.619,−39.340) <0.01
acute hepatitis B <1 year 1990–2000 −2.684(−3.048,−2.318) <0.01
acute hepatitis B <1 year 2000–2009 −6.942(−7.290,−6.592) <0.01
acute hepatitis B <1 year 2009–2018 −4.826(−5.325,−4.325) <0.01
acute hepatitis B <1 year 2018–2021 3.642(2.076,5.233) <0.01
acute hepatitis B 2–4 years 1990–2001 −3.675(−3.955,−3.394) <0.01
acute hepatitis B 2–4 years 2001–2004 −9.060(−10.293,−7.811) <0.01
acute hepatitis B 2–4 years 2004–2019 −5.144(−5.336,−4.952) <0.01
acute hepatitis B 2–4 years 2019–2021 6.860(4.578,9.191) <0.01
acute hepatitis B 5–9 years 1990–1996 −1.007(−1.512,−0.498) <0.01
acute hepatitis B 5–9 years 1996–2001 −2.308(−3.142,−1.467) <0.01
acute hepatitis B 5–9 years 2001–2018 −6.290(−6.428,−6.152) <0.01
acute hepatitis B 5–9 years 2018–2021 −4.120(−5.275,−2.950) <0.01
acute hepatitis B 10–14 years 1990–2001 −0.383(−0.614,−0.152) <0.01
acute hepatitis B 10–14 years 2001–2011 −4.174(−4.516,−3.830) <0.01
acute hepatitis B 10–14 years 2011–2016 −7.841(−8.450,−7.229) <0.01
acute hepatitis B 10–14 years 2016–2021 −6.017(−6.837,−5.190) <0.01
acute hepatitis B 15–19 years 1990–1994 −2.055(−3.178,−0.920) <0.01
acute hepatitis B 15–19 years 1994–2006 −0.560(−0.774,−0.345) <0.01
acute hepatitis B 15–19 years 2006–2015 −3.671(−3.991,−3.350) <0.01
acute hepatitis B 15–19 years 2015–2021 −7.310(−7.760,−6.857) <0.01
typhoid fever <1 year 1990–2000 −2.684(−3.048,−2.318) <0.01
typhoid fever <1 year 2000–2009 −6.942(−7.290,−6.592) <0.01
typhoid fever <1 year 2009–2016 −4.826(−5.325,−4.325) <0.01
typhoid fever <1 year 2016–2021 3.642(2.076,5.233) <0.01
typhoid fever 2–4 years 1990–2001 −3.675(−3.955,−3.394) <0.01
typhoid fever 2–4 years 2001–2004 −9.060(−10.293,−7.811) <0.01
typhoid fever 2–4 years 2004–2015 −5.144(−5.336,−4.952) <0.01
typhoid fever 2–4 years 2015–2021 6.860(4.578,9.191) <0.01
typhoid fever 5–9 years 1990–1996 −1.007(−1.512,−0.498) <0.01
typhoid fever 5–9 years 1996–2001 −2.308(−3.142,−1.467) <0.01
typhoid fever 5–9 years 2001–2018 −6.290(−6.428,−6.152) <0.01
typhoid fever 5–9 years 2018–2021 −4.120(−5.275,−2.950) <0.01
typhoid fever 10–14 years 1990–2001 −0.383(−0.614,−0.152) <0.01
typhoid fever 10–14 years 2001–2011 −4.174(−4.516,−3.830) <0.01
typhoid fever 10–14 years 2011–2016 −7.841(−8.450,−7.229) <0.01
typhoid fever 10–14 years 2016–2021 −6.017(−6.837,−5.190) <0.01
typhoid fever 15–19 years 1990–1994 −2.055(−3.178,−0.920) <0.01
typhoid fever 15–19 years 1994–2006 −0.560(−0.774,−0.345) <0.01
typhoid fever 15–19 years 2006–2015 −3.671(−3.991,−3.350) <0.01
typhoid fever 15–19 years 2015–2021 −7.310(−7.760,−6.857) <0.01
measles <1 year 1990–2001 −0.694(−1.616,0.237)
measles <1 year 2001–2012 −7.459(−8.318,−6.591) <0.01
measles <1 year 2012–2019 −9.610(−11.265,−7.924) <0.01
measles <1 year 2019–2021 −32.932(−37.415,−28.129) <0.01
measles 2–4 years 1990–2001 −0.880(−1.580,−0.175) <0.01
measles 2–4 years 2001–2011 −7.376(−8.236,−6.508) <0.01
measles 2–4 years 2011–2019 −9.830(−11.263,−8.374) <0.01
measles 2–4 years 2019–2021 −34.536(−38.344,−30.493) <0.01
measles 5–9 years 1990–2002 −1.361(−2.075,−0.642) <0.01
measles 5–9 years 2002–2011 −6.662(−7.703,−5.610) <0.01
measles 5–9 years 2011–2019 −9.979(−11.178,−8.765) <0.01
measles 5–9 years 2019–2021 −35.834(−39.657,−31.770) <0.01
measles 10–14 years 1990–2001 −2.018(−2.711,−1.321) <0.01
measles 10–14 years 2001–2011 −5.396(−6.426,−4.354) <0.01
measles 10–14 years 2011–2018 −9.856(−11.028,−8.669) <0.01
measles 10–14 years 2018–2021 −36.928(−40.600,−33.030) <0.01
measles 15–19 years 1990–1999 −0.412(−1.583,0.773)
measles 15–19 years 1999–2011 −5.501(−6.222,−4.774) <0.01
measles 15–19 years 2011–2018 −8.721(−10.003,−7.421) <0.01
measles 15–19 years 2018–2021 −38.333(−42.202,−34.205) <0.01
meningitis <1 year 1990–2005 −1.071(−1.167,−0.974) <0.01
meningitis <1 year 2005–2011 −3.254(−3.553,−2.955) <0.01
meningitis <1 year 2011–2017 −5.028(−5.398,−4.656) <0.01
meningitis <1 year 2017–2021 −0.672(−1.395,0.057)
meningitis 2–4 years 1990–2001 −1.226(−1.384,−1.068) <0.01
meningitis 2–4 years 2001–2009 −2.794(−3.045,−2.543) <0.01
meningitis 2–4 years 2009–2019 −6.422(−6.594,−6.249) <0.01
meningitis 2–4 years 2019–2021 −1.534(−2.693,−0.362) <0.01
meningitis 5–9 years 1990–2005 −1.123(−1.187,−1.058) <0.01
meningitis 5–9 years 2005–2010 −2.978(−3.347,−2.606) <0.01
meningitis 5–9 years 2010–2015 −8.645(−9.137,−8.151) <0.01
meningitis 5–9 years 2015–2021 −1.394(−1.618,−1.168) <0.01
meningitis 10–14 years 1990–1995 −0.242(−0.616,0.133)
meningitis 10–14 years 1995–2010 −1.337(−1.440,−1.234) <0.01
meningitis 10–14 years 2010–2015 −5.824(−6.177,−5.470) <0.01
meningitis 10–14 years 2015–2021 −1.439(−1.808,−1.069) <0.01
meningitis 15–19 years 1990–1997 0.587(0.401,0.774) <0.01
meningitis 15–19 years 1997–2011 −1.887(−1.975,−1.800) <0.01
meningitis 15–19 years 2011–2015 −4.377(−4.740,−4.013) <0.01
Meningitis 15–19 years 2015–2021 −0.734(−1.019,−0.448) <0.01

Regional and national trends

In 2021, the disease burden was predominated by acute hepatitis A and varicella and herpes zoster, which accounted for the largest share of cases. All 21 regions had high incidence rates, with Eastern Sub-Saharan Africa (6548.54 per 100,000 population) and Western Sub-Saharan Africa (6099.39 per 100,000 population) having the highest incidence rates of acute hepatitis A (Table 4, Fig. 7A). The incidence of acute hepatitis A was highest in all 21 regions, with the highest incidence rates in Eastern Sub-Saharan Africa (6,548.54 per 100,000 population) and Western Sub-Saharan Africa (6,099.39 per 100,000 population). Western Sub-Saharan Africa (3043.63 per 100,000) and Oceania (2983.62 per 100,000) had the highest incidence of varicella and herpes zoster. From 1990 to 2021, 10 countries/areas exhibited an increasing trend. The top three being the Kingdom of Spain, the Kingdom of Thailand, and Japan, with an EAPC ranging from 0.94 to 1.00 (Table 5; Fig. 8).The incidence of varicella and herpes zoster has increased in 57 countries, the top three being the Russian Federation, Czech Republic and Republic of Slovenia, with EAPCs ranging from 0.99 to 1.28.

Table 4.

Incidence, disability-adjusted life-years (DALYs), and Estimated annual percentage changes (EAPCs) for vaccine preventable diseases (VPDs) among children and adolescents from 1990 to 2021 at the regional level

Location Incidence DALYs □
1990 2021 Estimated annual
percentage
change, 1990–2021
1990 2021 Estimated annual
percentage
change, 1990–2021
Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI)
acute hepatitis A
Andean Latin America

1,105,813.80

(1044528.34,

1171028.13)

5833.55

(5510.25,

6177.58)

1,276,908.78

(1200166.83,

1356207.06)

5393.82

(5069.65,

5728.78)

−0.29(−0.33,−0.25)

3644.05

(2839.51,

4586.03)

19.22(14.98,24.19) 1835.20(1330.56,2495.84) 7.75(5.62,10.54) −3.12(−3.22,−3.03)
Australasia

110,438.78

(96625.66,

124754.32)

1760.50(1540.30,1988.70)

142,804.60

(125092.34,

161333.53)

1893.51(1658.66,2139.20) 0.24(0.11,0.38) 168.77(104.64,251.10) 2.69(1.67,4.00) 200.04(118.08,306.45) 2.65(1.57,4.06) −0.22(−0.43,−0.00)
Caribbean

833,277.03

(779435.30,

891261.55)

5518.76(5162.17,5902.79) 765,936.19(709597.49,821862.21) 5018.40(4649.27,5384.82) −0.36(−0.43,−0.30)

5273.31

(2973.77,

9007.27)

34.92(19.70,59.65)

2630.77

(1665.26,

3933.64)

17.24(10.91,25.77) −2.41(−2.52,−2.30)
Central Asia

1,974,408.04

(1845755.43,

2107415.58)

6252.11(5844.72,6673.29)

1,934,293.45

(1795827.90,

2078820.63)

5586.47(5186.56,6003.88) −0.16(−0.38,0.06)

56,642.40

(45058.01,

70530.57)

179.36(142.68,223.34) 3774.56(2816.41,5109.79) 10.90(8.13,14.76) −8.87(−9.30,−8.44)
Central Europe

1,413,185.78

(1278651.27,

1539387.11)

3598.79(3256.19,3920.17)

744,533.88

(670854.31,

814816.98)

3160.53(2847.77,3458.88) −0.15(−0.29,−0.01) 2835.04(2112.49,3752.48) 7.22(5.38,9.56) 1078.15(704.31,1536.04) 4.58(2.99,6.52) −1.29(−1.51,−1.08)
Central Latin America

4,996,322.80

(4718906.64,

5297355.19)

6046.53(5710.80,6410.84)

4,352,153.87

(4116918.43,

4613919.35)

5103.07(4827.25,5410.00) −0.48(−0.60,−0.36) 20,892.06(17993.01,24327.62) 25.28(21.78,29.44) 7322.65(5478.72,9725.80) 8.59(6.42,11.40) −3.29(−3.52,−3.07)
Central Sub−Saharan Africa 2,403,249.22(2255647.64,2560899.07) 7755.37(7279.06,8264.11)

4,346,371.85

(4069419.55,

4624301.65)

5908.55(5532.05,6286.37) −0.81(−0.84,−0.77)

60,504.86

(21219.69,

128346.87)

195.25(68.48,414.18) 11,635.71(5967.32,20783.78) 15.82(8.11,28.25) −7.78(−8.27,−7.29)
East Asia

23,018,656.70

(21361624.00,

24648720.69)

5002.53(4642.42,5356.79)

12,601,760.41

(11297941.67,

13841048.16)

3653.20(3275.23,4012.46) −0.78(−0.97,−0.59)

401,894.74

(270926.96,

533849.75)

87.34(58.88,116.02) 18,293.02(11960.31,26826.66) 5.30(3.47,7.78) −9.11(−10.19,−8.03)
Eastern Europe

2,697,630.41

(2441921.48,

2942380.67)

4009.83(3629.74,4373.64)

1,782,756.36

(1614146.75,

1938004.33)

3862.16(3496.88,4198.49) 0.07(−0.10,0.25) 4831.95(3548.59,6550.80) 7.18(5.27,9.74) 2525.86(1659.79,3748.44) 5.47(3.60,8.12) −1.34(−1.52,−1.16)
Eastern Sub−Saharan Africa

8,418,387.63

(7861455.43,

8949724.70)

7591.15(7088.94,8070.27)

14,903,480.23

(13971227.68,

15801765.95)

6548.54(6138.91,6943.25) −0.46(−0.50,−0.42)

163,192.59

(99926.41,

231825.89)

147.16(90.11,209.05)

73,919.56

(39664.60,

135310.05)

32.48(17.43,59.45) −4.78(−4.87,−4.70)
High−income Asia Pacific

953,823.22

(842664.76,

1057764.89)

1895.26(1674.39,2101.80)

600,119.38

(526422.74,

674277.92)

1949.13(1709.77,2190.00) 0.39(0.22,0.56) 2583.09(1935.31,3359.70) 5.13(3.85,6.68) 910.18(590.02,1332.36) 2.96(1.92,4.33) −1.99(−2.17,−1.81)
High−income North America 1,558,490.18(1370000.18,1759189.52) 1906.88(1676.25,2152.44)

1,706,116.87

(1493486.62,

1911125.44)

1905.04(1667.62,2133.95) −0.14(−0.26,−0.02) 2542.67(1696.20,3524.50) 3.11(2.08,4.31) 2720.43(1738.69,3979.23) 3.04(1.94,4.44) −0.50(−0.67,−0.33)
North Africa and Middle East

11,085,772.85

(10384462.88,

11840858.69)

6271.22(5874.49,6698.37)

12,076,196.92

(11265398.27,

12823145.02)

5106.39(4763.55,5422.24) −0.53(−0.61,−0.44)

292,100.65

(207832.42,

391468.24)

165.24(117.57,221.45) 50,353.97(34448.42,70393.68) 21.29(14.57,29.77) −6.39(−6.72,−6.07)
Oceania

163,553.69

(149136.77,

177929.60)

4858.43(4430.17,5285.47)

341,847.31

(313078.78,

368982.34)

5352.76(4902.29,5777.64) 0.35(0.26,0.44) 2805.75(1402.96,4860.92) 83.35(41.68,144.40) 1710.35(924.26,2930.48) 26.78(14.47,45.89) −3.94(−4.13,−3.75)
South Asia

45,993,868.90

(41770387.33,

50818741.86)

8479.25(7700.63,9368.75)

35,539,142.37

(33293893.14,

37701584.46)

5199.62(4871.13,5516.00) −1.57(−1.77,−1.37)

3,195,730.39

(2517390.69,

3954452.07)

589.15(464.10,729.03)

867,553.17

(510863.65,

1628347.91)

126.93(74.74,238.24) −4.12(−4.94,−3.30)
Southeast Asia

10,104,432.01

(9354748.59,

10933307.55)

4594.99(4254.07,4971.92)

9,314,686.56

(8498354.24,

10161147.18)

4062.73(3706.68,4431.93) −0.34(−0.40,−0.27)

144,348.30

(103278.48,

185373.99)

65.64(46.97,84.30) 24,792.71(18799.09,33301.44) 10.81(8.20,14.52) −6.08(−6.27,−5.89)
Southern Latin America

981,225.38

(900856.37,

1063307.18)

5063.26(4648.55,5486.82)

740,262.87

(667803.73,

812483.21)

3794.34(3422.94,4164.52) −0.93(−1.00,−0.86) 2269.67(1715.31,3258.66) 11.71(8.85,16.82) 1097.38(728.80,1608.49) 5.62(3.74,8.24) −2.74(−2.92,−2.55)
Southern Sub−Saharan Africa

1,712,365.32

(1594516.88,

1827456.30)

6471.36(6025.99,6906.31) 1,872,770.37(1748856.06,1985615.72) 5990.09(5593.75,6351.03) −0.03(−0.13,0.07) 7524.08(5108.41,11773.66) 28.43(19.31,44.49) 4354.55(3111.35,6327.28) 13.93(9.95,20.24) −0.86(−1.61,−0.10)
Tropical Latin America

3,275,658.83

(3049331.89,

3491420.44)

4729.39(4402.62,5040.91)

2,640,379.68

(2395936.95,

2870123.29)

3965.28(3598.18,4310.30) −0.78(−1.00,−0.56) 10,352.36(8753.77,12529.65) 14.95(12.64,18.09) 3846.61(2620.00,5541.38) 5.78(3.93,8.32) −3.10(−3.27,−2.93)
Western Europe

1,668,527.63

(1486509.13,

1857833.98)

1696.60(1511.52,1889.09)

1,499,590.83

(1311595.28,

1689528.54)

1635.13(1430.14,1842.23) −0.04(−0.07,−0.00) 2688.93(1762.71,3799.95) 2.73(1.79,3.86) 2238.51(1446.42,3306.42) 2.44(1.58,3.61) −0.29(−0.42,−0.17)
Western Sub−Saharan Africa

7,750,050.62

(7267341.25,

8258576.33)

7209.74(6760.68,7682.81)

16,381,504.36

(15458189.57,

17389741.34)

6099.39(5755.61,6474.79) −0.50(−0.54,−0.47) 139,092.02(52847.58,286576.28) 129.39(49.16,266.60) 38,689.27(24262.56,58334.02) 14.41(9.03,21.72) −7.71(−8.24,−7.17)
varicella and herpes zoster
Andean Latin America

531,584.16

(511808.09,

546079.50)

2804.29(2699.97,2880.76)

611,651.69

(589136.76,

630587.88)

2583.69(2488.58,2663.68) 1.09(0.53,1.65) 7092.17(5037.67,9607.88) 37.41(26.58,50.68) 2359.08(1690.43,3221.70) 9.97(7.14,13.61) −4.18(−4.28,−4.09)
Australasia

153,733.90

(148588.91,

159698.85)

2450.66(2368.65,2545.75) 183,446.23(177281.45,190237.48) 2432.40(2350.66,2522.45) 0.54(0.32,0.77) 203.86(171.18,243.67) 3.25(2.73,3.88) 269.58(208.63,346.44) 3.57(2.77,4.59) −0.27(−0.73,0.18)
Caribbean

414,959.95

(398666.54,

426934.94)

2748.26(2640.35,2827.57)

385,912.40

(372561.67,

396505.86)

2528.49(2441.02,2597.90) 0.40(0.01,0.79) 6983.46(4646.23,9755.49) 46.25(30.77,64.61) 5411.30(3260.63,8269.34) 35.45(21.36,54.18) −0.62(−0.89,−0.36)
Central Asia 945,631.61(918101.90,980733.73) 2994.41(2907.24,3105.57) 999,614.45(973278.26,1035045.41) 2887.00(2810.94,2989.33) 0.30(0.24,0.36) 2432.69(1862.47,3036.08) 7.70(5.90,9.61) 1789.17(1258.21,2443.65) 5.17(3.63,7.06) −0.88(−0.99,−0.76)
Central Europe 921,186.08(896804.72,956203.85) 2345.87(2283.78,2435.05) 560,859.68(545211.90,584485.62) 2380.84(2314.42,2481.13) 0.27(−0.11,0.65) 2127.49(1851.01,2485.86) 5.42(4.71,6.33) 377.39(268.31,536.03) 1.60(1.14,2.28) −4.02(−4.33,−3.71)
Central Latin America 2,364,218.33(2314207.62,2412518.65) 2861.17(2800.64,2919.62)

1,989,570.90

(1958187.87,

2027588.30)

2332.85(2296.05,2377.43) 0.09(0.01,0.17) 24,223.06(22112.40,26535.50) 29.31(26.76,32.11) 6801.56(5408.61,8621.28) 7.98(6.34,10.11) −4.63(−5.08,−4.18)
Central Sub−Saharan Africa

1,102,016.05

(1067016.63,

1131618.93)

3556.25(3443.30,3651.78)

2,127,602.78

(2084664.86,

2183435.51)

2892.31(2833.94,2968.21) 0.08(0.03,0.12) 26,433.49(16975.86,37770.63) 85.30(54.78,121.89) 27,896.79(17652.67,40841.57) 37.92(24.00,55.52) −2.17(−2.43,−1.91)
East Asia

11,690,038.26

(11425450.72,

12027772.67)

2540.54(2483.04,2613.94)

7,679,056.02

(7128139.52,

8302502.71)

2226.13(2066.42,2406.86) 0.06(−0.06,0.17) 118,473.58(100855.82,139558.46) 25.75(21.92,30.33) 12,575.10(9808.90,16038.55) 3.65(2.84,4.65) −6.33(−6.57,−6.08)
Eastern Europe

1,677,914.15

(1615656.31,

1760844.11)

2494.10(2401.56,2617.37) 1,011,203.98(970443.15,1056083.96) 2190.67(2102.36,2287.90) 0.04(−0.05,0.12) 4631.41(4209.44,5193.29) 6.88(6.26,7.72) 2876.04(2483.47,3271.02) 6.23(5.38,7.09) 0.92(0.45,1.39)
Eastern Sub−Saharan Africa

3,820,646.09

(3697204.52,

3925922.86)

3445.21(3333.90,3540.14)

6,477,813.44

(6348079.69,

6625171.43)

2846.33(2789.33,2911.08) 0.03(−0.09,0.16) 101,426.49(76688.30,136743.27) 91.46(69.15,123.31) 104,865.61(77002.57,136543.00) 46.08(33.83,60.00) −1.87(−2.01,−1.74)
High−income Asia Pacific

1,067,868.65

(1030826.14,

1103545.05)

2121.87(2048.27,2192.76)

671,170.52

(641557.07,

699209.29)

2179.90(2083.72,2270.97) −0.03(−0.15,0.10) 2930.17(2267.81,3811.55) 5.82(4.51,7.57) 785.25(552.46,1141.56) 2.55(1.79,3.71) −2.64(−2.98,−2.29)
High−income North America 2,209,451.61(2152227.96,2278812.52) 2703.36(2633.34,2788.23)

2,090,096.61

(2032294.62,

2152517.15)

2333.79(2269.25,2403.49) −0.13(−0.15,−0.11) 4608.65(4130.00,5253.50) 5.64(5.05,6.43) 3146.77(2559.12,3954.12) 3.51(2.86,4.42) −1.26(−1.74,−0.77)
North Africa and Middle East

5,122,957.30

(4934358.53,

5332168.73)

2898.06(2791.37,3016.41)

6,164,509.86

(5964439.43,

6409230.89)

2606.65(2522.05,2710.13) −0.25(−0.32,−0.17) 56,130.82(45057.68,72123.81) 31.75(25.49,40.80) 31,287.96(23394.57,39797.60) 13.23(9.89,16.83) −2.32(−2.48,−2.16)
Oceania

98,575.65

(92876.92,

102754.91)

2928.23(2758.95,3052.38) 190,545.47(179886.73,198931.49) 2983.62(2816.72,3114.93) −0.26(−0.35,−0.17) 1445.99(938.67,2149.00) 42.95(27.88,63.84) 2618.71(1658.84,3920.60) 41.00(25.97,61.39) 0.09(−0.11,0.30)
South Asia

15,368,031.52

(14604236.29,

15915375.63)

2833.19(2692.38,2934.10)

15,792,557.03

(15031277.72,

16327924.12)

2310.56(2199.18,2388.89) −0.32(−0.46,−0.18) 259,963.68(206516.44,317659.74) 47.93(38.07,58.56) 151,868.62(122678.74,190796.74) 22.22(17.95,27.91) −2.46(−2.53,−2.38)
Southeast Asia

5,247,785.65

(4670847.59,

5720758.51)

2386.43(2124.07,2601.51) 5,167,763.44(4626028.29,5605339.11) 2253.99(2017.71,2444.85) −0.36(−0.46,−0.26) 69,181.15(56614.84,84852.20) 31.46(25.75,38.59) 35,631.15(28916.65,43563.27) 15.54(12.61,19.00) −2.13(−2.31,−1.95)
Southern Latin America 529,151.28(517562.81,544742.94) 2730.50(2670.70,2810.95) 428,434.51(409912.14,450103.43) 2196.01(2101.07,2307.08) −0.42(−0.50,−0.35) 2984.83(2528.97,3492.52) 15.40(13.05,18.02) 1324.68(1045.82,1669.07) 6.79(5.36,8.56) −2.50(−2.69,−2.30)
Southern Sub−Saharan Africa

757,214.23

(740729.45,

775749.31)

2861.66(2799.36,2931.71)

807,813.81

(793611.43,

827549.91)

2583.81(2538.38,2646.93) −0.55(−0.65,−0.45) 7955.28(6462.01,9813.80) 30.06(24.42,37.09) 7881.57(5963.28,10619.54) 25.21(19.07,33.97) −0.12(−0.36,0.13)
Tropical Latin America 1,686,978.75(1656360.78,1727505.23) 2435.66(2391.45,2494.17)

1,720,679.24

(1693878.67,

1751321.89)

2584.09(2543.84,2630.11) −0.56(−0.62,−0.50) 17,587.77(14884.13,21201.01) 25.39(21.49,30.61) 8055.84(6241.08,9907.06) 12.10(9.37,14.88) −1.79(−2.70,−0.87)
Western Europe

2,369,217.44

(2305478.66,

2435408.36)

2409.07(2344.26,2476.38)

2,178,846.34

(2117552.70,

2255853.18)

2375.78(2308.95,2459.75) −0.59(−0.61,−0.57) 4961.83(4276.75,5993.55) 5.05(4.35,6.09) 2909.89(2213.77,3923.98) 3.17(2.41,4.28) −1.37(−1.47,−1.27)
Western Sub−Saharan Africa

3,801,608.61

(3666562.09,

3913196.45)

3536.57(3410.94,3640.38)

8,174,450.64

(7989272.51,

8357411.63)

3043.63(2974.68,3111.75) −0.62(−0.68,−0.56) 80,005.92(62039.92,103608.15) 74.43(57.71,96.38) 118,850.09(82890.01,157517.26) 44.25(30.86,58.65) −1.36(−1.49,−1.22)
acute hepatitis E
Andean Latin America

78,263.24

(59522.03,

102050.42)

412.87(314.00,538.35) 93,388.32(70455.34,120545.17) 394.48(297.61,509.20) −0.20(−0.22,−0.18) 116.71(68.28,183.27) 10.40(3.82,26.45) 116.21(68.21,194.65) 15.25(6.61,29.57) −0.81(−0.89,−0.73)
Australasia 8807.59(6766.29,11204.56) 140.40(107.86,178.61)

10,797.29

(8310.98,

13818.08)

143.17(110.20,183.22) 0.03(0.01,0.05) 12.71(8.53,18.67) 3.21(1.54,4.79) 15.06(9.73,23.08) 1.58(0.95,2.29) 0.06(−0.17,0.30)
Caribbean

60,485.62

(45984.59,

80149.31)

400.59(304.55,530.83) 60,244.42(45825.40,80171.24) 394.72(300.25,525.28) −0.04(−0.10,0.02) 125.26(71.42,204.68) 0.86(0.73,1.03) 126.38(75.00,192.30) 0.30(0.22,0.40) 0.03(−0.05,0.12)
Central Asia

119,601.14

(90671.46,

154270.37)

378.73(287.12,488.51)

128,098.76

(96889.53,

168634.76)

369.96(279.83,487.04) −0.13(−0.20,−0.06) 943.92(677.32,1370.93) 1.08(0.69,1.48) 220.28(149.52,335.34) 0.61(0.38,0.99) −4.44(−5.07,−3.81)
Central Europe 176,063.89(133430.59,231452.36) 448.36(339.79,589.41)

101,505.05

(77326.41,

133743.33)

430.89(328.25,567.74) −0.09(−0.15,−0.03) 424.03(269.44,580.97) 4.30(1.69,10.61) 144.08(90.50,233.32) 1.68(0.80,3.50) −1.75(−1.95,−1.56)
Central Latin America

197,885.93

(152383.05,

253366.99)

239.48(184.41,306.62)

198,800.41

(151632.20,

262075.18)

233.10(177.79,307.29) 0.00(−0.03,0.03) 1959.46(1608.04,2338.56) 0.73(0.57,0.96) 573.37(400.98,782.49) 0.49(0.35,0.72) −4.28(−4.84,−3.71)
Central Sub−Saharan Africa

170,882.42

(133618.36,

220795.34)

551.44(431.19,712.51)

400,721.78

(310006.43,

517046.81)

544.75(421.43,702.88) −0.04(−0.06,−0.02) 1620.37(329.38,3817.54) 2.99(2.14,4.34) 1234.33(489.05,2563.22) 0.64(0.43,0.97) −3.44(−3.78,−3.09)
East Asia

3,481,997.71

(2705282.64,

4424230.24)

756.73(587.93,961.50)

2,481,668.95

(1915528.41,

3165882.31)

719.43(555.30,917.78) −0.36(−0.51,−0.22) 14,814.09(5794.36,22979.97) 0.45(0.34,0.59) 3080.12(1849.85,4961.31) 0.25(0.16,0.37) −4.71(−5.13,−4.29)
Eastern Europe 120,161.25(90753.46,154454.46) 178.61(134.90,229.59) 78,082.71(59163.60,101478.45) 169.16(128.17,219.84) 0.05(−0.08,0.18) 300.77(228.27,400.22) 2.37(1.95,2.83) 113.66(75.52,172.28) 0.67(0.47,0.92) −1.67(−1.84,−1.50)
Eastern Sub−Saharan Africa

643,031.17

(497975.56,

830456.40)

579.84(449.04,748.85)

1,275,025.97

(986821.30,

1635677.57)

560.24(433.61,718.71) −0.08(−0.10,−0.05) 9121.33(1933.93,27957.06) 0.26(0.19,0.38) 11,268.18(3801.07,26250.81) 0.27(0.19,0.40) −1.73(−1.82,−1.63)
High−income Asia Pacific

133,013.95

(103397.07,

173445.73)

264.30(205.45,344.64)

83,225.68

(64115.75,

108162.64)

270.31(208.24,351.30) 0.06(0.02,0.11) 369.57(287.76,483.03) 0.83(0.47,1.36) 151.51(106.35,221.36) 0.83(0.49,1.26) −1.79(−2.14,−1.44)
High−income North America

133,038.27

(101651.46,

168459.02)

162.78(124.37,206.12)

144,955.67

(111401.97,

185538.86)

161.86(124.39,207.17) −0.03(−0.05,−0.01) 215.16(157.42,307.09) 3.22(1.26,4.99) 244.14(172.94,356.24) 0.89(0.54,1.44) 0.15(−0.09,0.40)
North Africa and Middle East

375,531.51

(288209.55,

482579.16)

212.44(163.04,272.99)

482,973.72

(362946.88,

637763.13)

204.22(153.47,269.68) −0.11(−0.17,−0.06) 11,941.79(4520.01,27147.19) 0.20(0.14,0.30) 4403.35(2141.64,8497.52) 0.20(0.13,0.31) −4.23(−4.42,−4.04)
Oceania 15,050.13(11622.07,19619.28) 447.07(345.24,582.80) 28,904.09(21801.82,37585.70) 452.59(341.38,588.53) 0.02(−0.01,0.04) 144.79(56.95,357.11) 8.23(1.74,25.21) 107.05(51.24,223.39) 4.95(1.67,11.53) −3.42(−3.58,−3.26)
South Asia

3,932,386.61

(3085929.35,

4945631.56)

724.96(568.91,911.76)

4,929,235.56

(3879920.22,

6249623.97)

721.18(567.66,914.36) −0.06(−0.10,−0.01) 56,386.12(20726.86,143485.68) 6.76(2.56,15.36)

104,218.06

(45147.12,

202120.27)

1.86(0.91,3.59) 1.92(1.59,2.25)
Southeast Asia

781,834.84

(596756.14,

1016614.12)

355.54(271.37,462.31)

801,362.96

(609829.18,

1044714.05)

349.53(265.99,455.67) 0.07(0.01,0.12) 7064.12(3396.89,10543.21) 5.23(1.06,12.32) 3615.40(2173.98,5250.14) 1.68(0.66,3.48) −2.83(−3.08,−2.58)
Southern Latin America 14,937.79(11724.76,19018.58) 77.08(60.50,98.14)

13,724.14

(10472.37,

17825.91)

70.35(53.68,91.37) −0.25(−0.28,−0.21) 31.61(20.57,49.75) 0.16(0.11,0.23) 19.50(12.88,30.08) 0.21(0.15,0.29) −1.31(−1.63,−1.00)
Southern Sub−Saharan Africa 103,547.70(79226.66,133799.30) 391.33(299.41,505.65)

130,312.06

(100142.15,

170106.14)

416.81(320.31,544.09) 0.32(0.27,0.38) 693.20(251.11,1307.31) 2.62(0.95,4.94) 680.03(354.17,1078.10) 2.18(1.13,3.45) −0.20(−0.48,0.09)
Tropical Latin America 102,879.71(77621.81,131438.50) 148.54(112.07,189.77) 99,099.65(75583.32,127505.89) 148.83(113.51,191.49) 0.02(−0.01,0.05) 592.36(504.24,713.28) 18.18(3.01,51.49) 200.29(143.46,269.39) 2.57(0.95,5.17) −2.56(−3.10,−2.01)
Western Europe 106,663.56(82537.78,135391.34) 108.46(83.93,137.67)

100,081.42

(77565.67,

128176.56)

109.13(84.58,139.76) 0.16(0.07,0.24) 155.16(107.51,226.73) 0.16(0.11,0.26) 191.29(140.92,262.96) 0.10(0.07,0.15) 1.44(1.21,1.67)
Western Sub−Saharan Africa 438,903.34(338893.04,563058.55) 408.30(315.27,523.80)

1,104,589.60

(841727.98,

1430167.16)

411.28(313.40,532.50) 0.05(0.03,0.08) 19,544.38(3235.42,55348.29) 0.62(0.36,0.97) 6913.09(2548.52,13891.77) 0.49(0.29,0.82) −6.76(−7.29,−6.23)
pertussis
Andean Latin America 252,102.98(193369.58,320043.23) 1329.93(1020.09,1688.34)

84,714.13

(27792.01,

183801.64)

357.84(117.40,776.40) −3.08(−3.84,−2.33) 28,319.13(14020.88,55387.87) 995.84(258.37,2543.80) 1425.28(425.84,3376.32) 73.22(5.17,288.29) −7.27(−8.55,−5.97)
Australasia

29,133.93

(22510.26,

37120.33)

464.42(358.83,591.73) 200.65(49.61,457.57) 2.66(0.66,6.07) −5.20(−8.64,−1.63)

2,034,033.32

(249690.22,

5920018.34)

3.23(1.90,5.16) 89,738.90(10160.94,244543.58) 0.03(0.01,0.08) −4.72(−7.97,−1.36)
Caribbean

194,635.60

(149097.05,

247697.86)

1289.06(987.46,1640.49) 733.92(212.59,3452.20) 4.81(1.39,22.62) −4.37(−7.60,−1.03)

133,362.55

(76179.61,

234034.02)

1221.48(212.67,3397.40) 5216.58(1776.46,14790.99) 35.04(1.90,123.36) −3.27(−5.24,−1.26)
Central Asia

339,151.22

(260082.18,

432472.57)

1073.95(823.57,1369.46) 19,474.67(10614.02,33510.21) 56.25(30.65,96.78) −3.94(−5.43,−2.42) 39,051.36(7074.62,111021.91) 235.51(70.03,568.99) 20.64(2.01,108.34) 8.25(1.87,23.09) −5.17(−6.61,−3.71)
Central Europe

131,711.16

(101940.25,

169052.01)

335.41(259.60,430.50) 999.83(309.23,2210.45) 4.24(1.31,9.38) −2.71(−5.37,0.04)

74,372.67

(22116.95,

179686.53)

43.62(18.41,82.78) 2857.45(646.32,7995.44) 1.58(0.53,3.21) −5.43(−6.78,−4.07)
Central Latin America

1,195,377.89

(912547.40,

1522668.45)

1446.64(1104.36,1842.73) 82,479.08(48218.43,128878.88) 96.71(56.54,151.12) −2.88(−4.22,−1.52) 17,129.28(7227.96,32507.56) 161.39(92.19,283.23) 371.30(123.92,756.59) 6.12(2.08,17.34) −6.27(−7.34,−5.19)
Central Sub−Saharan Africa

839,829.16

(634771.35,

1065005.09)

2710.16(2048.43,3436.81)

970,854.70

(493784.22,

1701433.71)

1319.80(671.26,2312.96) −1.89(−2.25,−1.52) 7389.00(4902.02,10804.52) 3147.37(662.53,8305.37) 129.85(58.73,225.76) 902.84(188.27,2530.44) −3.09(−3.50,−2.67)
East Asia

3,206,868.86

(2481509.92,

4070585.68)

696.93(539.29,884.64) 128,961.40(67858.66,221970.17) 37.39(19.67,64.35) −5.17(−6.43,−3.90)

3,108,286.75

(1257723.13,

6544885.75)

442.05(54.26,1286.57)

1,438,092.65

(430801.96,

3504774.74)

26.01(2.95,70.89) −9.12(−9.79,−8.44)
Eastern Europe

878,633.79

(673584.03,

1118431.22)

1306.03(1001.23,1662.47) 13,217.74(6376.81,23927.53) 28.63(13.81,51.84) −3.63(−5.80,−1.41) 5174.52(3425.66,7553.82) 10.98(7.29,16.06) 95.33(54.60,170.97) 0.28(0.13,0.49) −4.11(−6.05,−2.13)
Eastern Sub−Saharan Africa

2,460,726.78

(1866566.34,

3132863.45)

2218.92(1683.15,2825.01)

1,261,463.95

(819051.91,

1837765.46)

554.28(359.89,807.51) −3.16(−3.83,−2.48) 1560.74(1096.04,2194.98) 2742.46(986.70,6202.34) 369.92(158.69,738.88) 444.55(165.01,920.43) −4.26(−4.97,−3.55)
High−income Asia Pacific

305,765.49

(237109.30,

386974.66)

607.56(471.14,768.92) 67.76(10.00,253.71) 0.22(0.03,0.82) −9.90(−13.60,−6.04) 3,041,311.34(1094221.72,6878236.54) 77.60(14.06,220.60)

1,011,732.04

(375544.85,

2094760.32)

0.07(0.01,0.35) −11.89(−14.27,−9.44)
High−income North America 146,979.64(111960.25,191294.45) 179.84(136.99,234.06) 41,977.20(19482.27,77228.41) 46.87(21.75,86.23) −0.98(−2.40,0.46)

184,431.20

(32111.12,

512972.25)

1.91(1.34,2.69) 5347.35(289.24,18827.23) 0.41(0.18,0.83) −0.83(−2.30,0.66)
North Africa and Middle East 2,261,486.03(1734683.51,2866573.51) 1279.32(981.31,1621.62)

370,487.70

(183839.99,

680686.03)

156.66(77.74,287.83) −2.64(−3.60,−1.68) 170,447.38(41140.22,437599.70) 884.25(386.01,1767.18) 25,299.24(6613.17,66066.02) 72.76(23.10,168.10) −4.12(−5.08,−3.15)
Oceania

63,519.01

(48201.87,

80875.05)

1886.86(1431.86,2402.43) 5359.36(2576.41,9425.41) 83.92(40.34,147.59) −2.03(−3.97,−0.06) 9,340,239.46(2493739.32,25785421.91) 1405.24(327.25,3727.84)

1,043,654.98

(218574.85,

2690977.24)

166.10(39.59,478.82) −1.22(−2.65,0.23)
South Asia

11,431,574.57

(8648949.85,

14528371.85)

2107.48(1594.49,2678.39)

2,044,642.41

(932289.21,

3661968.25)

299.15(136.40,535.77) −4.31(−5.14,−3.48) 47,305.97(11016.42,125493.61) 1721.93(459.74,4753.70) 10,607.65(2528.41,30579.22) 152.69(31.98,393.71) −5.44(−6.33,−4.54)
Southeast Asia

3,259,385.24

(2487407.79,

4151530.31)

1482.20(1131.15,1887.91) 124,816.59(75543.16,198458.21) 54.44(32.95,86.56) −2.97(−4.72,−1.19)

1,563,100.84

(682354.71,

3123877.32)

978.09(339.06,2108.95) 172,062.54(54624.74,397532.87) 29.58(9.47,67.64) −4.28(−5.87,−2.66)
Southern Latin America

154,015.31

(119284.94,

194585.56)

794.74(615.53,1004.09) 5494.23(2300.70,10700.73) 28.16(11.79,54.85) −4.73(−6.60,−2.82) 188,771.96(48976.77,482204.63) 22.47(15.06,31.47) 17,334.02(1224.46,68247.74) 0.46(0.14,1.10) −5.01(−7.65,−2.31)
Southern Sub−Saharan Africa 277,558.81(214658.69,352410.09) 1048.95(811.24,1331.83)

55,185.99

(22110.30,

111090.53)

176.51(70.72,355.33) −1.39(−3.20,0.45) 202.42(119.14,323.93) 644.15(155.48,1653.77) 2.23(0.53,5.97) 80.92(21.15,211.31) −1.75(−3.71,0.24)
Tropical Latin America 838,519.38(641694.47,1067324.98) 1210.65(926.48,1541.00)

114,746.81

(32890.83,

257103.41)

172.32(49.39,386.11) −4.54(−6.70,−2.33) 4354.18(2917.64,6098.78) 40.89(20.24,79.97) 89.50(27.07,214.05) 2.14(0.64,5.07) −5.15(−6.59,−3.69)
Western Europe

576,228.68

(446118.21,

730889.53)

585.92(453.62,743.18) 9521.05(5739.26,14905.74) 10.38(6.26,16.25) −5.73(−7.41,−4.03)

2,150,827.84

(745592.96,

4637596.86)

5.26(3.48,7.68) 67,816.23(21721.67,155084.87) 0.10(0.06,0.19) −4.99(−6.72,−3.22)
Western Sub−Saharan Africa

2,933,579.32

(2218586.14,

3725104.58)

2729.06(2063.91,3465.40)

1,746,765.04

(1106253.62,

2552749.94)

650.38(411.90,950.48) −2.43(−3.16,−1.70) 975,312.97(205306.42,2573684.81) 2891.58(1170.04,6088.59)

664,132.68

(138490.60,

1861410.06)

535.45(160.40,1304.95) −3.13(−3.85,−2.41)
acute hepatitis B
Andean Latin America 69,249.47(56592.13,83822.36) 365.32(298.54,442.19)

20,500.66

(16407.66,

25925.65)

86.60(69.31,109.51) −4.54(−5.20,−3.88)

255,437.53

(119752.62,

567940.62)

2.95(1.75,5.02) 462,048.61(248647.92,663969.31) 0.95(0.61,1.44) −4.06(−4.54,−3.58)
Australasia 41,851.14(32395.00,52453.41) 667.15(516.41,836.16) 6800.15(5479.01,8470.86) 90.17(72.65,112.32) −7.35(−7.97,−6.73) 42,021.08(30877.77,60909.89) 0.82(0.59,1.16) 11,043.13(6703.08,16596.92) 0.23(0.19,0.29) −5.08(−5.60,−4.57)
Caribbean 52,920.98(40621.63,69033.55) 350.49(269.04,457.21)

24,950.24

(18318.85,

32529.36)

163.47(120.02,213.13) −2.50(−2.65,−2.36) 2122.96(1818.36,2572.07) 3.08(1.47,8.48) 768.19(631.88,937.67) 3.57(1.78,7.69) −0.03(−0.34,0.28)
Central Asia

236,285.50

(189446.51,

290489.96)

748.22(599.90,919.86) 36,526.28(29665.62,44421.04) 105.49(85.68,128.29) −5.98(−7.11,−4.83) 1064.78(813.59,1385.33) 201.32(156.95,249.25) 159.83(119.63,207.53) 20.93(12.85,36.42) −6.93(−7.27,−6.59)
Central Europe

200,475.94

(163125.53,

244267.60)

510.53(415.41,622.05) 15,406.29(12446.19,18678.10) 65.40(52.83,79.29) −7.38(−7.95,−6.81) 1411.18(737.90,2776.53) 2.71(2.07,3.53) 535.02(260.52,1130.25) 0.68(0.51,0.88) −4.66(−5.65,−3.66)
Central Latin America

382,536.81

(280989.06,

506270.47)

462.94(340.05,612.69) 62,179.65(46330.31,82585.59) 72.91(54.32,96.83) −6.36(−6.70,−6.02) 1181.23(853.62,1664.96) 3.70(3.09,4.46) 153.85(121.49,200.63) 2.82(2.00,3.88) −0.28(−0.89,0.34)
Central Sub−Saharan Africa 833,901.73(605817.60,1089218.12) 2691.03(1955.00,3514.95)

1,019,467.85

(789709.99,

1290997.21)

1385.89(1073.55,1755.01) −2.22(−2.58,−1.86) 63,577.11(49564.07,78712.62) 121.04(28.41,359.51) 7246.43(4448.99,12609.33) 17.27(7.69,36.52) −5.94(−6.51,−5.37)
East Asia

9,365,119.12

(7408718.11,

11864839.24)

2035.28(1610.10,2578.53) 472,744.63(359119.41,619385.79) 137.05(104.11,179.56) −8.76(−9.94,−7.57) 125,595.14(42583.78,225475.01) 63.72(35.11,97.02) 37,583.90(23665.20,55302.04) 2.11(1.47,2.98) −11.34(−11.90,−10.78)
Eastern Europe

226,303.54

(167296.22,

302515.34)

336.38(248.67,449.67) 21,117.26(15482.56,28336.64) 45.75(33.54,61.39) −6.50(−7.82,−5.17) 14,203.98(12709.05,15538.47) 21.11(18.89,23.10) 1298.98(1068.13,1471.87) 2.81(2.31,3.19) −5.81(−6.55,−5.07)
Eastern Sub−Saharan Africa

1,750,536.84

(1355816.43,

2179064.13)

1578.52(1222.59,1964.94)

1,255,941.95

(965356.11,

1592792.91)

551.86(424.17,699.87) −3.60(−4.01,−3.18) 3056.56(2553.47,3684.76) 67.05(28.12,122.65) 2408.95(1705.22,3306.83) 31.17(17.47,51.90) −2.65(−2.86,−2.44)
High−income Asia Pacific

404,531.82

(329128.16,

506238.10)

803.81(653.98,1005.90) 86,124.33(67946.58,111418.87) 279.72(220.68,361.88) −2.61(−2.83,−2.39) 843.57(765.51,922.70) 2.35(1.70,3.31) 191.60(161.83,222.73) 0.50(0.39,0.65) −7.06(−8.69,−5.40)
High−income North America 139,933.71(111274.67,175116.58) 171.21(136.15,214.26)

31,595.25

(25219.28,

39940.52)

35.28(28.16,44.60) −5.53(−5.86,−5.19) 465.78(222.27,1280.86) 1.03(0.94,1.13) 544.53(271.32,1174.11) 0.21(0.18,0.25) −6.00(−6.67,−5.32)
North Africa and Middle East

1,505,525.11

(1193642.70,

1863241.46)

851.68(675.24,1054.04)

397,747.48

(316500.98,

480757.69)

168.19(133.83,203.29) −5.40(−5.73,−5.07)

293,198.25

(161571.95,

446416.44)

71.05(24.09,127.55) 7289.66(5066.04,10287.71) 15.89(10.01,23.38) −4.55(−4.89,−4.20)
Oceania

63,960.97

(46673.77,

82030.47)

1899.99(1386.46,2436.75) 61,979.85(47351.44,78768.51) 970.50(741.44,1233.38) −2.90(−3.20,−2.61) 51.63(37.25,72.53) 41.92(21.92,82.48) 17.47(14.05,21.94) 8.38(4.08,17.70) −5.72(−5.99,−5.46)
South Asia

3,986,682.01

(3036284.84,

5099497.62)

734.97(559.76,940.12)

1,891,681.91

(1429418.11,

2513823.15)

276.77(209.13,367.79) −2.61(−3.01,−2.21) 74,351.78(31186.36,136017.31) 47.09(22.08,104.70)

70,948.74

(39759.23,

118126.72)

67.60(36.38,97.14) 1.90(1.50,2.29)
Southeast Asia

3,156,895.68

(2513692.53,

3882663.96)

1435.60(1143.10,1765.64)

918,181.89

(739502.86,

1143638.49)

400.48(322.54,498.81) −4.36(−4.68,−4.05) 37,506.95(8802.84,111404.26) 19.11(14.04,27.70) 12,706.66(5659.30,26862.99) 4.82(2.92,7.24) −4.82(−5.03,−4.62)
Southern Latin America

31,617.78

(25571.69,

39382.29)

163.15(131.95,203.22) 5443.42(4251.99,6831.76) 27.90(21.79,35.02) −5.35(−6.12,−4.58) 809.33(681.03,963.24) 1.42(0.95,2.63) 168.47(136.13,208.12) 0.28(0.20,0.36) −5.38(−5.89,−4.87)
Southern Sub−Saharan Africa

384,259.17

(312843.40,

466573.98)

1452.19(1182.30,1763.27)

102,226.09

(79980.55,

129198.15)

326.97(255.82,413.24) −5.16(−5.51,−4.81) 1661.73(1014.20,2390.51) 6.28(3.83,9.03) 648.69(442.16,942.92) 2.07(1.41,3.02) −3.39(−3.82,−2.95)
Tropical Latin America

434,506.59

(342791.12,

550818.51)

627.34(494.92,795.27) 55,596.62(40987.33,73968.92) 83.49(61.55,111.09) −8.19(−9.00,−7.38) 369,592.61(140117.70,639917.33) 3.07(2.63,3.71) 133,103.37(79876.35,213269.15) 1.15(0.95,1.41) −3.49(−4.40,−2.58)
Western Europe

329,164.19

(258701.24,

415436.44)

334.70(263.05,422.43)

71,720.64

(55867.19,

92938.13)

78.20(60.92,101.34) −4.72(−4.82,−4.62) 275.87(183.67,509.01) 0.82(0.69,0.98) 53.86(39.72,70.66) 0.18(0.15,0.23) −5.50(−6.19,−4.82)
Western Sub−Saharan Africa

2,659,422.64

(2089955.77,

3313765.49)

2474.01(1944.25,3082.74)

2,881,817.20

(2255955.40,

3612717.31)

1073.00(839.97,1345.14) −2.76(−3.08,−2.43) 558.96(330.93,951.99) 343.83(130.35,595.30) 225.56(144.88,341.27) 49.56(29.74,79.41) −6.56(−7.20,−5.92)
typhoid fever
Andean Latin America 216.84(127.28,346.49) 1.14(0.67,1.83) 131.13(77.38,210.89) 0.55(0.33,0.89) −2.62(−2.80,−2.44) 114,400.06(49509.05,230838.39) 15.42(12.86,17.89) 23,713.70(10400.01,44618.31) 0.34(0.14,0.71) −12.60(−13.37,−11.82)
Australasia 5.40(2.54,10.05) 0.09(0.04,0.16) 7.12(3.32,14.14) 0.09(0.04,0.19) 0.47(0.31,0.62) 1258.85(653.71,2231.77) 0.00(0.00,0.00) 112.42(46.36,233.23) 0.00(0.00,0.00) −0.93(−1.97,0.13)
Caribbean 4590.84(3322.42,6205.66) 30.40(22.00,41.10) 1687.77(1198.29,2324.73) 11.06(7.85,15.23) −3.04(−3.17,−2.91) 9.89(5.44,19.15) 43.61(19.47,87.97) 3.08(1.26,6.87) 16.32(7.33,34.05) −2.72(−2.86,−2.58)
Central Asia 171.59(109.26,265.44) 0.54(0.35,0.84) 76.86(45.33,125.21) 0.22(0.13,0.36) −3.05(−3.18,−2.92) 7.17(4.32,12.43) 1.42(0.84,2.41) 2.99(1.58,5.36) 0.11(0.06,0.22) −7.93(−8.18,−7.69)
Central Europe 80.93(50.65,128.57) 0.21(0.13,0.33) 39.31(22.08,64.71) 0.17(0.09,0.27) −0.14(−0.59,0.32) 56.94(41.40,85.79) 0.02(0.01,0.03) 12.40(5.59,24.90) 0.01(0.01,0.02) −0.02(−0.65,0.61)
Central Latin America 10,270.08(7288.60,14025.21) 12.43(8.82,16.97) 3425.64(2399.57,4701.49) 4.02(2.81,5.51) −3.73(−3.94,−3.52) 446.90(266.01,760.75) 28.84(26.30,31.63) 39.22(20.20,77.85) 1.34(1.06,1.73) −9.04(−10.07,−8.00)
Central Sub−Saharan Africa

33,161.60

(23180.23,

45348.88)

107.01(74.80,146.34) 28,275.08(19242.52,38673.63) 38.44(26.16,52.57) −3.10(−3.21,−2.99) 794,467.37(367467.72,1508364.00) 99.47(45.61,202.71)

593,196.56

(269360.67,

1119812.26)

35.25(15.18,73.67) −2.74(−2.95,−2.54)
East Asia

100,953.73

(70193.24,

142374.37)

21.94(15.25,30.94) 31,056.19(22434.79,41577.73) 9.00(6.50,12.05) −2.48(−2.73,−2.22) 906,924.30(417890.51,1704769.75) 24.86(10.76,50.17)

739,307.29

(327372.64,

1475377.23)

6.87(3.01,12.93) −3.28(−3.61,−2.94)
Eastern Europe 198.21(125.11,302.02) 0.29(0.19,0.45) 118.04(76.09,178.43) 0.26(0.16,0.39) 0.03(−0.18,0.24) 34.06(28.20,41.15) 0.08(0.06,0.13) 7.07(4.73,11.11) 0.03(0.01,0.05) −2.73(−3.15,−2.32)
Eastern Sub−Saharan Africa

711,612.21

(506160.04,

956740.69)

641.69(456.42,862.73)

398,847.54

(283996.39,

527185.37)

175.25(124.79,231.64) −4.13(−4.18,−4.08) 414.41(346.73,490.45) 716.40(331.36,1360.14) 4.22(3.19,5.70) 260.65(118.36,492.04) −2.82(−2.98,−2.66)
High−income Asia Pacific 46.71(27.11,74.96) 0.09(0.05,0.15) 32.77(17.04,58.33) 0.11(0.06,0.19) 0.48(0.25,0.70)

23,834.46

(21730.60,

26134.35)

0.02(0.01,0.04) 1143.41(901.80,1472.48) 0.01(0.00,0.02) −1.76(−2.15,−1.36)
High−income North America 65.70(34.81,109.68) 0.08(0.04,0.13) 62.21(30.41,108.77) 0.07(0.03,0.12) −0.12(−0.27,0.03) 4.50(3.90,5.18) 0.01(0.00,0.01) 4.15(3.48,4.97) 0.00(0.00,0.01) −0.01(−1.30,1.30)
North Africa and Middle East

262,254.85

(189040.03,

349839.89)

148.36(106.94,197.90) 78,676.77(54175.53,107324.78) 33.27(22.91,45.38) −4.68(−4.74,−4.63) 36,816.25(16925.85,69894.45) 142.57(66.52,271.54) 35,215.05(16107.98,65072.28) 32.99(15.65,61.15) −4.22(−4.37,−4.07)
Oceania

39,334.59

(26582.90,

54153.50)

1168.45(789.66,1608.65) 27,438.93(18763.73,39072.37) 429.65(293.81,611.81) −3.28(−3.34,−3.21) 6585.09(2939.19,13283.10) 1093.64(502.79,2076.24) 2490.61(1118.64,5197.33) 551.41(252.22,1018.92) −2.25(−2.39,−2.11)
South Asia

10,947,689.38

(7974107.58,

14788121.93)

2018.27(1470.08,2726.28)

3,370,919.10

(2365480.02,

4573742.04)

493.19(346.09,669.17) −4.71(−5.00,−4.43)

9,104,404.93

(4507507.63,

15447302.55)

1678.45(830.99,2847.81)

3,735,941.18

(1873909.18,

6208563.82)

546.59(274.17,908.36) −3.57(−3.77,−3.37)
Southeast Asia

1,891,988.34

(1365586.87,

2463795.43)

860.38(621.00,1120.41)

555,802.94

(397337.94,

751339.16)

242.42(173.30,327.71) −3.97(−4.04,−3.91) 0.17(0.13,0.22) 753.73(384.17,1378.06) 0.09(0.05,0.17) 272.97(132.40,484.12) −3.15(−3.20,−3.10)
Southern Latin America 318.01(186.48,512.28) 1.64(0.96,2.64) 104.70(62.21,161.18) 0.54(0.32,0.83) −3.41(−3.65,−3.17) 2923.86(2437.23,3390.79) 2.14(1.79,2.53) 81.36(33.81,168.76) 0.02(0.02,0.03) −11.81(−13.97,−9.60)
Southern Sub−Saharan Africa 681.99(465.20,937.93) 2.58(1.76,3.54) 668.25(458.40,908.96) 2.14(1.47,2.91) −0.19(−0.29,−0.09)

252,021.69

(117591.35,

480009.72)

2.24(0.98,4.52)

78,024.58

(37008.45,

144621.11)

2.22(1.00,4.33) 0.60(0.20,1.00)
Tropical Latin America 1713.33(1019.54,2678.22) 2.47(1.47,3.87) 322.25(199.94,486.75) 0.48(0.30,0.73) −5.34(−5.57,−5.11) 591.59(260.35,1196.39) 1.82(0.94,3.22) 693.29(314.18,1353.40) 0.17(0.07,0.35) −7.05(−7.20,−6.91)
Western Europe 633.60(401.10,981.98) 0.64(0.41,1.00) 548.96(340.73,854.83) 0.60(0.37,0.93) −0.20(−0.38,−0.02)

1,657,462.15

(844792.47,

3030377.89)

0.03(0.03,0.04)

625,832.50

(303547.94,

1109947.78)

0.01(0.01,0.01) −3.34(−3.90,−2.78)
Western Sub−Saharan Africa 751,445.17(521820.10,995277.48) 699.06(485.44,925.89)

484,754.51

(344745.53,

644817.39)

180.49(128.36,240.09) −4.44(−4.56,−4.32) 30,824.19(14134.70,62814.99) 843.70(388.76,1585.92)

25,928.59

(11166.51,

54193.94)

275.27(121.89,549.33) −3.39(−3.50,−3.29)
measles
Andean Latin America 3106.77(3005.98,3228.08) 16.39(15.86,17.03) 0.00(0.00,0.00) 0.00(0.00,0.00) −22.99(−29.91,−15.38) 11,843.23(9142.52,14417.53) 62.48(48.23,76.06) 0.00(0.00,0.00) 0.00(0.00,0.00) −34.16(−40.47,−27.17)
Australasia 7692.58(7528.50,7876.76) 122.63(120.01,125.56) 2.26(1.63,3.55) 0.03(0.02,0.05) −13.81(−18.85,−8.46) 171.21(128.21,210.15) 2.73(2.04,3.35) 0.03(0.01,0.17) 0.00(0.00,0.00) −10.53(−16.75,−3.84)
Caribbean 9869.59(9662.62,10066.27) 65.37(64.00,66.67) 0.00(0.00,0.00) 0.00(0.00,0.00) −29.42(−36.53,−21.51) 4230.39(2773.59,5969.72) 28.02(18.37,39.54) 0.07(0.04,0.14) 0.00(0.00,0.00) −33.62(−42.29,−23.66)
Central Asia

18,577.30

(18341.76,

18841.03)

58.83(58.08,59.66) 34.49(23.44,47.45) 0.10(0.07,0.14) −6.18(−12.15,0.18) 7142.02(5097.93,9377.04) 22.62(16.14,29.69) 732.57(457.15,1096.58) 2.12(1.32,3.17) −9.59(−15.01,−3.84)
Central Europe 144,918.34(144234.42,145566.14) 369.05(367.30,370.70) 21.17(13.07,30.30) 0.09(0.06,0.13) −5.32(−11.74,1.56) 19,192.98(14383.84,24769.66) 48.88(36.63,63.08) 123.84(57.61,205.45) 0.53(0.24,0.87) −5.55(−11.85,1.21)
Central Latin America

109,286.87

(108690.70,

109915.23)

132.26(131.54,133.02) 0.00(0.00,0.00) 0.00(0.00,0.00) −17.60(−27.12,−6.83) 118,830.31(99285.53,139470.25) 143.81(120.15,168.79) 0.01(0.00,0.02) 0.00(0.00,0.00) −31.68(−37.75,−25.02)
Central Sub−Saharan Africa

1,932,050.74

(669151.66,

4191674.22)

6234.80(2159.38,13526.68) 185,861.42(140504.53,232017.80) 252.66(191.00,315.41) −7.83(−9.15,−6.49) 1,951,718.29(630481.01,4310740.73) 6298.27(2034.59,13910.92) 68,388.96(23054.68,119657.38) 92.97(31.34,162.66) −9.83(−11.34,−8.31)
East Asia

222,896.52

(132788.10,

415526.46)

48.44(28.86,90.30) 722.88(659.22,782.63) 0.21(0.19,0.23) −12.47(−15.09,−9.77) 25,921.79(17091.06,36469.90) 5.63(3.71,7.93) 1158.41(701.95,1814.57) 0.34(0.20,0.53) −12.20(−14.78,−9.53)
Eastern Europe

28,384.17

(28066.41,

28698.49)

42.19(41.72,42.66) 21.19(14.32,28.70) 0.05(0.03,0.06) −7.84(−14.30,−0.89) 890.46(610.50,1292.49) 1.32(0.91,1.92) 2.36(0.75,4.88) 0.01(0.00,0.01) −7.30(−12.31,−1.99)
Eastern Sub−Saharan Africa

6,574,998.25

(2274618.48,

14325437.28)

5928.90(2051.10,12917.74)

1,381,078.33

(988812.22,

1905690.96)

606.84(434.48,837.35) −7.15(−7.79,−6.51) 13,237,424.08(4650391.27,26949990.82) 11,936.64(4193.42,24301.73)

1,946,843.07

(932997.94,

3576554.31)

855.44(409.96,1571.53) −8.38(−8.86,−7.90)
High−income Asia Pacific 6587.81(6432.75,6744.98) 13.09(12.78,13.40) 6.77(1.97,12.49) 0.02(0.01,0.04) −14.92(−19.57,−10.01) 4179.00(3730.88,4625.91) 8.30(7.41,9.19) 1.01(0.34,1.94) 0.00(0.00,0.01) −17.28(−20.12,−14.33)
High−income North America 28,844.92(28345.04,29566.40) 35.29(34.68,36.18) 50.58(37.68,65.16) 0.06(0.04,0.07) −9.10(−13.05,−4.98) 2051.72(1343.07,2955.23) 2.51(1.64,3.62) 3.26(0.91,7.47) 0.00(0.00,0.01) −8.75(−12.23,−5.13)
North Africa and Middle East

6,295,001.65

(2190768.05,

13826293.95)

3561.08(1239.32,7821.53) 357,726.91(300257.86,411478.64) 151.26(126.96,173.99) −8.62(−9.55,−7.69)

4,417,138.04

(1637154.58,

8859421.45)

2498.77(926.14,5011.77) 369,838.00(228203.21,583254.83) 156.39(96.50,246.63) −10.42(−11.27,−9.56)
Oceania

148,124.01

(52058.60,

324992.03)

4400.09(1546.42,9654.03) 15,571.71(9765.49,25658.50) 243.83(152.91,401.77) −4.36(−6.17,−2.51) 112,964.25(40971.19,227809.06) 3355.65(1217.07,6767.16) 7901.13(3083.28,17396.77) 123.72(48.28,272.40) −5.11(−7.06,−3.13)
South Asia

29,234,487.52

(10054213.82,

63495398.83)

5389.56(1853.56,11705.77) 684,611.72(523481.16,842123.04) 100.16(76.59,123.21) −8.55(−10.46,−6.59)

19,506,340.34

(7135270.72,

38838655.42)

3596.11(1315.43,7160.15) 175,952.89(98439.99,301947.22) 25.74(14.40,44.18) −11.65(−13.43,−9.84)
Southeast Asia

9,170,078.35

(3174248.55,

20242787.94)

4170.09(1443.49,9205.40)

146,493.02

(107824.58,

186252.13)

63.89(47.03,81.24) −8.15(−9.62,−6.66)

4,589,296.12

(1673924.83,

9213169.21)

2086.98(761.22,4189.69) 31,853.85(17650.86,55214.11) 13.89(7.70,24.08) −11.13(−12.41,−9.83)
Southern Latin America 3964.43(3847.43,4080.14) 20.46(19.85,21.05) 2.42(0.45,6.08) 0.01(0.00,0.03) −19.55(−27.19,−11.11) 1795.94(1201.97,2318.69) 9.27(6.20,11.96) 0.24(0.05,0.53) 0.00(0.00,0.00) −25.93(−32.72,−18.45)
Southern Sub−Saharan Africa 1,071,340.66(381192.55,2375031.59) 4048.80(1440.60,8975.70) 30,268.93(22908.39,38704.57) 96.82(73.27,123.80) −6.95(−9.25,−4.59)

465,558.27

(166311.64,

966728.67)

1759.43(628.52,3653.45) 8739.34(3956.71,16454.82) 27.95(12.66,52.63) −8.20(−10.48,−5.87)
Tropical Latin America

60,065.00

(59592.54,

60528.07)

86.72(86.04,87.39) 695.34(641.40,748.54) 1.04(0.96,1.12) −3.22(−16.20,11.77) 24,893.18(19539.63,29801.44) 35.94(28.21,43.03) 33.67(12.58,69.32) 0.05(0.02,0.10) −12.56(−23.51,−0.05)
Western Europe

226,074.85

(225149.59,

226987.80)

229.88(228.94,230.81) 67.87(53.32,83.58) 0.07(0.06,0.09) −15.11(−18.44,−11.64) 1870.77(1559.37,2175.86) 1.90(1.59,2.21) 35.34(23.90,46.05) 0.04(0.03,0.05) −8.61(−10.80,−6.36)
Western Sub−Saharan Africa

6,791,116.47

(2354018.34,

14735365.58)

6317.66(2189.90,13708.05)

1,956,184.13

(1633919.20,

2295166.54)

728.35(608.36,854.57) −7.22(−8.21,−6.22)

14,077,636.54

(5071323.34,

28355390.26)

13,096.18(4717.76,26378.52)

2,228,046.42

(1241162.79,

3535984.51)

829.58(462.13,1316.57) −9.22(−10.02,−8.40)
meningitis
Andean Latin America 7524.67(6210.20,8921.29) 39.70(32.76,47.06) 2237.24(1778.21,2847.99) 9.45(7.51,12.03) −4.99(−5.16,−4.81) 83,699.51(73045.18,100030.25) 441.54(385.34,527.69) 11,458.49(8836.84,15150.47) 48.40(37.33,64.00) −7.06(−7.27,−6.86)
Australasia 998.35(769.45,1253.16) 15.91(12.27,19.98) 449.81(345.98,588.49) 5.96(4.59,7.80) −4.26(−4.69,−3.82) 5860.78(5459.03,6249.85) 93.43(87.02,99.63) 1488.39(1289.64,1702.02) 19.74(17.10,22.57) −5.62(−6.28,−4.96)
Caribbean

21,105.96

(17665.78,

24651.08)

139.78(117.00,163.26) 9711.01(8184.52,11444.90) 63.63(53.62,74.99) −2.31(−2.51,−2.11)

207,368.99

(175401.96,

249498.53)

1373.40(1161.68,1652.42)

69,744.42

(49670.01,

98849.14)

456.96(325.44,647.66) −3.12(−3.37,−2.87)
Central Asia

29,372.05

(24499.80,

34609.62)

93.01(77.58,109.59) 11,073.89(8689.06,14024.63) 31.98(25.10,40.50) −3.72(−3.88,−3.56)

216,024.28

(197265.19,

237555.45)

684.06(624.65,752.24) 29,361.14(23316.90,37865.32) 84.80(67.34,109.36) −6.76(−7.03,−6.49)
Central Europe 12,884.66(10126.32,16284.94) 32.81(25.79,41.47) 2023.10(1536.11,2659.49) 8.59(6.52,11.29) −4.35(−4.50,−4.21)

84,570.76

(80131.22,

89214.77)

215.37(204.06,227.19) 4603.10(3886.98,5403.77) 19.54(16.50,22.94) −6.80(−7.09,−6.50)
Central Latin America

32,128.68

(25788.24,

38769.12)

38.88(31.21,46.92) 8698.81(6827.27,11223.52) 10.20(8.01,13.16) −4.42(−4.80,−4.04)

320,241.32

(298936.53,

344794.40)

387.55(361.77,417.27) 48,381.06(38257.80,61205.90) 56.73(44.86,71.77) −6.20(−6.73,−5.66)
Central Sub−Saharan Africa

106,970.97

(88480.82,

127563.23)

345.20(285.53,411.65)

76,365.89

(64925.89,

89348.54)

103.81(88.26,121.46) −4.21(−4.67,−3.75)

1,180,991.27

(898247.80,

1510601.86)

3811.10(2898.68,4874.77)

565,705.99

(399315.85,

949525.54)

769.03(542.84,1290.80) −5.05(−5.66,−4.44)
East Asia

265,558.86

(203582.08,

334209.32)

57.71(44.24,72.63) 30,529.71(22751.70,40559.04) 8.85(6.60,11.76) −6.52(−6.83,−6.20)

2,622,819.43

(1997954.50,

3274512.14)

570.00(434.21,711.63)

143,482.39

(118614.98,

170442.79)

41.59(34.39,49.41) −8.13(−8.68,−7.58)
Eastern Europe

44,416.96

(34940.12,

54460.79)

66.02(51.94,80.95) 8571.35(6430.84,11137.38) 18.57(13.93,24.13) −3.57(−3.97,−3.16)

175,332.12

(167021.81,

184344.34)

260.62(248.27,274.01)

20,537.54

(18793.28,

22461.64)

44.49(40.71,48.66) −4.45(−4.92,−3.98)
Eastern Sub−Saharan Africa

484,891.81

(396899.32,

582968.43)

437.24(357.90,525.68)

256,853.72

(216500.15,

299270.16)

112.86(95.13,131.50) −4.62(−4.87,−4.37)

5,309,761.32

(4143606.29,

6819119.52)

4787.99(3736.43,6149.03)

2,059,220.32

(1517053.01,

2803294.37)

904.81(666.59,1231.76) −5.38(−5.64,−5.12)
High−income Asia Pacific

8026.42

(5604.45,

11293.87)

15.95(11.14,22.44) 3077.36(2224.76,4231.68) 9.99(7.23,13.74) −2.05(−2.55,−1.55)

26,513.45

(23624.19,

29353.44)

52.68(46.94,58.33) 2038.59(1854.72,2242.98) 6.62(6.02,7.28) −6.49(−6.79,−6.19)
High−income North America

17,873.53

(12558.72,

24572.65)

21.87(15.37,30.07) 3448.34(2651.11,4494.58) 3.85(2.96,5.02) −6.09(−6.77,−5.41) 70,593.89(67561.88,74098.38) 86.37(82.66,90.66) 12,361.58(11252.72,13624.84) 13.80(12.56,15.21) −5.87(−6.20,−5.53)
North Africa and Middle East

124,822.00

(101336.24,

148777.98)

70.61(57.33,84.16)

55,372.63

(44656.51,

69165.78)

23.41(18.88,29.25) −3.58(−3.93,−3.23)

1,170,385.87

(975490.53,

1445685.84)

662.09(551.83,817.82)

282,316.84

(206192.19,

401503.26)

119.38(87.19,169.77) −5.12(−5.61,−4.63)
Oceania 5052.14(4222.93,6038.63) 150.08(125.44,179.38) 5047.59(4262.93,5959.91) 79.04(66.75,93.32) −2.68(−2.85,−2.50) 28,466.79(22234.16,37189.75) 845.62(660.48,1104.74)

21,006.60

(14061.22,

31620.98)

328.93(220.18,495.13) −4.48(−5.08,−3.87)
South Asia 895,309.27(726840.89,1088496.54) 165.06(134.00,200.67)

364,197.73

(298120.33,

437832.16)

53.28(43.62,64.06) −3.68(−4.03,−3.33)

7,335,668.33

(6204798.50,

8759651.91)

1352.38(1143.89,1614.90)

2,214,388.92

(1735944.69,

2856879.38)

323.98(253.98,417.98) −4.06(−4.44,−3.69)
Southeast Asia

254,658.26

(203321.22,

315190.19)

115.81(92.46,143.33)

67,624.00

(54385.41,

81743.54)

29.50(23.72,35.65) −4.34(−4.60,−4.08) 2,700,461.63(2181029.70,3330722.76) 1228.03(991.82,1514.65)

653,853.92

(519068.55,

809190.91)

285.19(226.40,352.94) −4.37(−4.66,−4.07)
Southern Latin America

7021.44

(5841.22,

8465.96)

36.23(30.14,43.69) 1826.59(1445.71,2316.48) 9.36(7.41,11.87) −4.46(−4.66,−4.25)

56,216.87

(52638.35,

59947.51)

290.09(271.62,309.34) 7774.10(6629.95,9062.96) 39.85(33.98,46.45) −5.76(−5.98,−5.54)
Southern Sub−Saharan Africa

25,444.70

(20665.65,

30657.62)

96.16(78.10,115.86) 16,665.40(13931.15,19770.75) 53.30(44.56,63.24) −1.85(−2.18,−1.52)

230,026.10

(191440.40,

273985.96)

869.31(723.49,1035.45) 128,324.07(100976.09,158740.48) 410.45(322.97,507.73) −2.07(−2.51,−1.63)
Tropical Latin America

58,016.34

(47361.86,

69916.84)

83.76(68.38,100.95)

15,928.76

(12473.94,

20314.86)

23.92(18.73,30.51) −5.08(−5.45,−4.70)

518,643.87

(468492.74,

569096.38)

748.82(676.41,821.66) 43,722.45(36559.49,51689.53) 65.66(54.90,77.63) −7.96(−8.32,−7.59)
Western Europe 18,346.91(13761.08,23869.22) 18.66(13.99,24.27) 5585.23(4224.07,7427.95) 6.09(4.61,8.10) −3.95(−4.13,−3.78)

101,103.52

(98630.60,

103728.12)

102.80(100.29,105.47)

18,014.70

(16319.14,

19821.76)

19.64(17.79,21.61) −5.37(−5.59,−5.16)
Western Sub−Saharan Africa

584,403.96

(466080.57,

715995.71)

543.66(433.59,666.08)

493,516.61

(413377.51,

582897.59)

183.75(153.91,217.03) −3.57(−3.93,−3.22)

6,461,308.51

(5013798.31,

8318127.78)

6010.84(4664.25,7738.21)

4,375,006.34

(2697629.24,

6813248.32)

1628.96(1004.42,2536.80) −3.95(−4.40,−3.50)

Fig. 7.

Fig. 7

Global incidence and burden of 8 vaccine-preventable diseases in children and adolescents in 21 regions, 1990–2021

Table 5.

Incidence, disability-adjusted life-years (DALYs), and Estimated annual percentage changes (EAPCs) for vaccine preventable diseases (VPDs) among children and adolescents from 1990 to 2021 at the national level

Cause Location Incidence DALYs □
1990 2021 Estimated annual percentage change, 1990–2021 1990 2021 Estimated annual percentage change, 1990–2021
Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI) Cases,(95%CI) Rate per 100,000 people (95% UI)
Acute hepatitis A American Samoa 1053.68(940.70,1166.11) 4403.78(3931.60,4873.67) 709.13(640.40,781.11) 3707.14(3347.85,4083.46) −0.56(−0.61,−0.50) 1.94(1.32,2.69) 8.10(5.53,11.25) 1.28(0.90,1.85) 6.71(4.72,9.69) −0.72(−0.84,−0.61)
Acute hepatitis A Antigua and Barbuda 1222.54(1129.37,1312.89) 5117.36(4727.38,5495.55) 1005.62(912.69,1085.54) 4304.14(3906.40,4646.20) −0.67(−0.71,−0.63) 1.75(1.23,2.48) 7.34(5.14,10.38) 1.31(0.83,1.94) 5.61(3.57,8.30) −0.95(−0.99,−0.91)
Acute hepatitis A Arab Republic of Egypt 1,860,614.83(1734991.18,1993501.34) 6663.44(6213.54,7139.34) 2,391,551.22(2192466.65,2576575.94) 5137.57(4709.89,5535.04) −0.54(−0.66,−0.42) 69,769.29(29296.25,134423.88) 249.87(104.92,481.41) 5720.01(3255.63,9692.81) 12.29(6.99,20.82) −8.49(−9.15,−7.83)
Acute hepatitis A Argentine Republic 643,529.58(580187.77,706333.81) 4940.04(4453.80,5422.15) 508,717.36(459514.47,559451.87) 3710.15(3351.31,4080.17) −1.02(−1.09,−0.96) 1605.94(1168.03,2569.40) 12.33(8.97,19.72) 782.59(515.46,1132.11) 5.71(3.76,8.26) −2.97(−3.16,−2.77)
Acute hepatitis A Australia 94,144.75(81884.50,106665.08) 1820.25(1583.21,2062.33) 121,334.61(105958.78,136888.28) 1944.99(1698.52,2194.32) 0.21(0.07,0.36) 143.12(87.74,213.39) 2.77(1.70,4.13) 168.80(98.37,261.09) 2.71(1.58,4.19) −0.28(−0.52,−0.04)
Acute hepatitis A Barbados 4012.83(3683.33,4305.78) 4726.31(4338.21,5071.34) 2675.25(2429.39,2897.38) 4030.18(3659.80,4364.82) −0.56(−0.60,−0.52) 10.15(7.54,13.20) 11.96(8.88,15.55) 4.49(3.10,6.31) 6.77(4.67,9.50) −2.10(−2.27,−1.92)
Acute hepatitis A Belize 6117.27(5730.62,6530.23) 5963.62(5586.68,6366.21) 8090.18(7514.59,8646.56) 4785.69(4445.20,5114.81) −0.69(−0.73,−0.66) 11.41(8.52,15.03) 11.12(8.31,14.65) 10.40(6.71,15.46) 6.15(3.97,9.14) −2.04(−2.16,−1.92)
Acute hepatitis A Bermuda 785.19(714.94,849.63) 4937.95(4496.11,5343.16) 477.18(433.60,515.67) 4150.42(3771.33,4485.16) −0.55(−0.57,−0.53) 0.94(0.60,1.42) 5.92(3.78,8.96) 0.63(0.39,0.95) 5.47(3.42,8.26) −0.29(−0.33,−0.25)
Acute hepatitis A Bolivarian Republic of Venezuela 539,854.48(506876.83,573920.25) 5948.10(5584.76,6323.44) 448,161.73(413505.08,482590.76) 5120.80(4724.80,5514.19) −0.18(−0.31,−0.04) 1203.44(917.43,1671.97) 13.26(10.11,18.42) 826.27(598.11,1142.42) 9.44(6.83,13.05) −0.99(−1.26,−0.73)
Acute hepatitis A Bosnia and Herzegovina 54,589.01(48941.02,60165.72) 3684.08(3302.91,4060.44) 19,697.91(17358.20,21837.42) 2961.74(2609.95,3283.44) −0.80(−1.01,−0.59) 95.77(60.72,138.72) 6.46(4.10,9.36) 28.64(18.40,43.41) 4.31(2.77,6.53) −1.42(−1.64,−1.19)
Acute hepatitis A Brunei Darussalam 2697.67(2375.07,3056.74) 2345.27(2064.81,2657.44) 2663.53(2335.58,3045.01) 2062.55(1808.59,2357.96) −0.49(−0.56,−0.41) 21.24(10.90,37.85) 18.47(9.48,32.90) 6.10(3.99,9.22) 4.73(3.09,7.14) −4.97(−5.32,−4.61)
Acute hepatitis A Burkina Faso 403,238.60(377749.52,429324.23) 7127.86(6677.30,7588.96) 855,219.95(801410.99,909835.70) 6678.37(6258.18,7104.87) −0.18(−0.21,−0.15) 3554.42(1370.94,7300.18) 62.83(24.23,129.04) 2253.76(1068.28,4820.86) 17.60(8.34,37.65) −3.85(−4.18,−3.52)
Acute hepatitis A Canada 111,248.12(97275.53,126455.49) 1451.43(1269.14,1649.84) 114,121.22(98567.99,131186.37) 1386.84(1197.83,1594.22) 0.41(−0.02,0.84) 162.87(100.11,248.22) 2.12(1.31,3.24) 165.92(96.49,262.35) 2.02(1.17,3.19) 0.12(−0.23,0.47)
Acute hepatitis A Central African Republic 125,814.83(116840.79,134852.32) 8403.67(7804.25,9007.32) 177,169.61(166759.12,188146.67) 6121.95(5762.22,6501.25) −0.88(−0.97,−0.79) 5550.23(1693.03,12785.02) 370.72(113.08,853.96) 2007.93(628.05,4114.48) 69.38(21.70,142.17) −4.73(−5.04,−4.42)
Acute hepatitis A Commonwealth of Dominica 1751.44(1635.19,1861.98) 5344.23(4989.51,5681.53) 800.42(735.59,858.89) 4120.38(3786.68,4421.40) −0.87(−0.94,−0.81) 2.92(2.10,4.05) 8.90(6.40,12.35) 1.32(0.89,1.92) 6.82(4.60,9.86) −0.99(−1.08,−0.90)
Acute hepatitis A Commonwealth of the Bahamas 5228.19(4798.46,5626.94) 4856.18(4457.03,5226.55) 4559.73(4162.82,4934.60) 3955.82(3611.48,4281.04) −0.71(−0.78,−0.64) 8.35(5.77,11.82) 7.76(5.36,10.98) 6.94(4.44,10.42) 6.02(3.85,9.04) −0.97(−1.06,−0.89)
Acute hepatitis A Cook Islands 340.27(305.41,373.54) 3951.80(3546.95,4338.19) 193.85(175.04,213.86) 3740.16(3377.32,4126.34) −0.21(−0.28,−0.15) 0.47(0.30,0.69) 5.46(3.51,8.00) 0.27(0.17,0.41) 5.22(3.28,7.82) −0.16(−0.23,−0.10)
Acute hepatitis A Czech Republic 81,645.23(71257.06,91034.47) 2682.27(2340.99,2990.73) 56,992.29(50503.04,64371.56) 2566.62(2274.38,2898.94) 0.60(0.33,0.88) 251.79(198.40,313.42) 8.27(6.52,10.30) 84.33(54.82,124.47) 3.80(2.47,5.61) −1.53(−2.02,−1.03)
Acute hepatitis A Democratic People’s Republic of Korea 341,049.75(304338.63,376021.66) 4378.41(3907.11,4827.38) 216,873.35(193217.85,241177.02) 3284.82(2926.53,3652.93) −1.10(−1.16,−1.03) 1536.75(695.77,3829.05) 19.73(8.93,49.16) 313.98(192.74,481.25) 4.76(2.92,7.29) −4.47(−4.88,−4.05)
Acute hepatitis A Democratic Republic of Sao Tome and Principe 4580.56(4297.70,4853.99) 6554.51(6149.76,6945.77) 5594.68(5293.60,5933.26) 5495.59(5199.84,5828.17) −0.47(−0.61,−0.33) 24.96(12.85,40.35) 35.71(18.39,57.74) 6.56(4.30,9.46) 6.44(4.22,9.29) −5.58(−6.02,−5.14)
Acute hepatitis A Democratic Republic of the Congo 1,496,946.13(1395197.33,1598722.76) 6914.24(6444.28,7384.34) 2,819,175.14(2648182.26,3010042.32) 5884.68(5527.75,6283.09) −0.46(−0.52,−0.39) 12,235.31(6284.12,20522.89) 56.51(29.03,94.79) 5068.71(2975.02,7818.91) 10.58(6.21,16.32) −5.04(−5.57,−4.50)
Acute hepatitis A Democratic Republic of Timor−Leste 21,886.16(19630.78,24119.34) 5381.88(4827.27,5931.02) 28,625.31(25642.17,31515.94) 4176.25(3741.03,4597.98) −0.94(−0.99,−0.90) 162.91(63.93,466.47) 40.06(15.72,114.71) 54.96(32.43,81.37) 8.02(4.73,11.87) −5.90(−6.41,−5.38)
Acute hepatitis A Democratic Socialist Republic of Sri Lanka 224,580.10(197147.35,251254.77) 3101.88(2722.99,3470.31) 176,313.22(155778.38,200287.68) 2555.29(2257.68,2902.75) −0.53(−0.61,−0.44) 810.10(564.21,1127.83) 11.19(7.79,15.58) 272.22(178.63,398.27) 3.95(2.59,5.77) −3.67(−4.08,−3.27)
Acute hepatitis A Dominican Republic 211,115.70(198531.75,225481.19) 6028.19(5668.86,6438.38) 202,608.50(186212.70,218378.01) 5207.53(4786.11,5612.84) −0.77(−0.90,−0.63) 448.35(323.15,636.83) 12.80(9.23,18.18) 264.70(175.33,374.83) 6.80(4.51,9.63) −3.32(−3.74,−2.89)
Acute hepatitis A Eastern Republic of Uruguay 49,696.40(45200.48,53841.61) 4614.23(4196.79,4999.10) 33,248.58(29684.72,36565.03) 3680.67(3286.15,4047.81) −0.80(−0.89,−0.70) 83.94(60.31,114.78) 7.79(5.60,10.66) 47.34(30.11,70.17) 5.24(3.33,7.77) −1.59(−1.71,−1.47)
Acute hepatitis A Federal Democratic Republic of Ethiopia 2,276,357.30(2127971.04,2432674.32) 7725.05(7221.48,8255.52) 3,680,471.58(3419795.76,3939983.93) 6434.62(5978.87,6888.33) −0.64(−0.68,−0.60) 53,330.96(28062.91,84174.37) 180.98(95.23,285.65) 26,388.16(11981.89,50996.14) 46.13(20.95,89.16) −4.31(−4.56,−4.07)
Acute hepatitis A Federal Democratic Republic of Nepal 1,175,905.44(1087270.27,1262507.03) 11,362.70(10506.23,12199.53) 637,602.64(603306.63,675102.12) 5119.45(4844.08,5420.54) −2.49(−2.83,−2.14) 88,854.70(43695.04,152054.95) 858.60(422.22,1469.30) 8800.69(5292.89,13581.74) 70.66(42.50,109.05) −7.92(−8.05,−7.80)
Acute hepatitis A Federal Republic of Germany 237,526.13(208668.79,267464.31) 1370.57(1204.06,1543.32) 218,335.26(188594.36,250547.42) 1369.13(1182.64,1571.13) 0.40(0.25,0.55) 379.12(256.66,554.64) 2.19(1.48,3.20) 305.72(183.91,454.78) 1.92(1.15,2.85) −0.06(−0.23,0.11)
Acute hepatitis A Federal Republic of Nigeria 3,499,738.62(3274798.72,3730078.08) 7213.13(6749.52,7687.87) 7,312,743.38(6883534.89,7773806.12) 5723.26(5387.35,6084.11) −0.75(−0.84,−0.66) 109,478.05(32889.27,247180.27) 225.64(67.79,509.45) 22,623.44(12285.58,37208.09) 17.71(9.62,29.12) −8.99(−9.68,−8.30)
Acute hepatitis A Federal Republic of Somalia 365,985.28(340259.30,391130.55) 7733.71(7190.09,8265.06) 950,961.08(893526.43,1012821.37) 7438.45(6989.19,7922.32) −0.06(−0.16,0.05) 14,672.20(5710.97,27971.72) 310.04(120.68,591.08) 11,012.49(3137.96,29896.36) 86.14(24.55,233.85) −3.57(−3.89,−3.25)
Acute hepatitis A Federated States of Micronesia 1685.29(1491.16,1891.87) 2931.05(2593.42,3290.33) 1018.92(910.45,1134.20) 2458.54(2196.81,2736.68) −0.50(−0.68,−0.33) 7.94(2.83,17.53) 13.82(4.92,30.48) 2.00(1.18,3.03) 4.82(2.84,7.32) −3.48(−3.78,−3.17)
Acute hepatitis A Federative Republic of Brazil 3,168,057.12(2949356.83,3374940.38) 4714.89(4389.41,5022.79) 2,540,003.23(2304482.19,2760834.48) 3973.92(3605.44,4319.42) −0.77(−1.00,−0.54) 10,141.85(8590.68,12279.67) 15.09(12.79,18.28) 3700.00(2514.29,5318.05) 5.79(3.93,8.32) −3.12(−3.30,−2.95)
Acute hepatitis A French Republic 340,575.28(299539.70,380534.90) 2109.88(1855.66,2357.43) 273,607.89(238119.09,308474.36) 1737.01(1511.71,1958.36) −0.78(−0.89,−0.66) 528.01(330.95,753.97) 3.27(2.05,4.67) 414.70(256.97,636.27) 2.63(1.63,4.04) −0.95(−1.07,−0.83)
Acute hepatitis A Gabonese Republic 32,520.35(30490.04,34660.85) 6399.36(5999.84,6820.57) 44,016.71(40837.61,46844.34) 5322.14(4937.75,5664.03) −0.54(−0.60,−0.49) 197.56(65.69,382.84) 38.88(12.93,75.34) 58.17(39.61,86.32) 7.03(4.79,10.44) −5.16(−5.39,−4.93)
Acute hepatitis A Georgia 94,230.33(87042.29,100816.14) 5244.29(4844.25,5610.81) 46,304.07(42352.24,49922.63) 4982.70(4557.45,5372.09) 0.09(−0.08,0.26) 207.27(132.52,294.69) 11.54(7.38,16.40) 53.97(33.67,78.90) 5.81(3.62,8.49) −2.07(−2.20,−1.93)
Acute hepatitis A Grand Duchy of Luxembourg 1337.42(1162.34,1522.47) 1515.79(1317.36,1725.52) 1864.43(1613.83,2115.59) 1381.89(1196.15,1568.05) −0.34(−0.38,−0.31) 1.88(1.14,2.83) 2.13(1.30,3.21) 2.58(1.52,4.03) 1.91(1.13,2.99) −0.27(−0.30,−0.23)
Acute hepatitis A Greenland 508.27(447.19,571.65) 2840.80(2499.40,3195.05) 399.53(349.06,454.94) 2599.31(2270.96,2959.83) −0.37(−0.46,−0.28) 1.12(0.73,1.81) 6.27(4.07,10.09) 0.54(0.34,0.82) 3.49(2.18,5.35) −1.81(−2.08,−1.53)
Acute hepatitis A Grenada 2336.03(2149.97,2505.28) 5540.98(5099.65,5942.44) 1309.12(1190.18,1410.41) 4348.58(3953.46,4685.03) −0.73(−0.78,−0.67) 4.28(2.93,6.16) 10.15(6.94,14.61) 1.71(1.08,2.54) 5.68(3.60,8.44) −1.84(−1.93,−1.74)
Acute hepatitis A Guam 2212.19(1972.97,2459.66) 4085.70(3643.89,4542.75) 1916.50(1720.49,2116.08) 3952.75(3548.50,4364.38) −0.23(−0.35,−0.11) 3.47(2.42,4.71) 6.41(4.47,8.71) 2.65(1.77,3.87) 5.47(3.64,7.98) −0.16(−0.40,0.09)
Acute hepatitis A Hashemite Kingdom of Jordan 124,450.53(116170.24,132458.95) 5935.73(5540.80,6317.70) 243,460.99(227875.50,258592.10) 4943.28(4626.83,5250.51) −0.56(−0.60,−0.52) 340.89(223.33,527.99) 16.26(10.65,25.18) 320.08(209.84,469.03) 6.50(4.26,9.52) −3.07(−3.27,−2.86)
Acute hepatitis A Hellenic Republic 58,970.35(51880.72,67081.13) 2098.17(1845.92,2386.76) 38,542.42(33678.50,43931.52) 2022.91(1767.62,2305.75) −0.00(−0.15,0.14) 95.73(61.46,142.49) 3.41(2.19,5.07) 57.55(35.46,87.90) 3.02(1.86,4.61) −0.44(−0.59,−0.29)
Acute hepatitis A Hungary 64,254.45(57046.63,71476.29) 2213.98(1965.62,2462.81) 43,567.30(38332.92,48802.60) 2323.12(2044.01,2602.28) 0.63(0.46,0.81) 151.36(111.28,200.71) 5.22(3.83,6.92) 62.01(40.20,91.63) 3.31(2.14,4.89) −0.48(−0.88,−0.08)
Acute hepatitis A Independent State of Papua New Guinea 107,095.24(97332.96,116604.21) 5031.15(4572.54,5477.87) 274,073.14(251135.39,296012.26) 5594.41(5126.21,6042.24) 0.38(0.28,0.47) 2140.10(939.36,3934.79) 100.54(44.13,184.85) 1441.79(720.56,2567.75) 29.43(14.71,52.41) −4.28(−4.48,−4.09)
Acute hepatitis A Independent State of Samoa 3698.38(3307.59,4104.60) 4037.77(3611.12,4481.27) 4173.40(3676.89,4634.73) 4134.45(3642.58,4591.48) 0.04(−0.03,0.11) 8.39(5.09,12.37) 9.16(5.56,13.50) 5.99(4.01,8.53) 5.93(3.97,8.45) −1.55(−1.71,−1.38)
Acute hepatitis A Ireland 24,675.11(21621.10,27969.16) 1856.92(1627.09,2104.82) 21,392.50(18661.93,24454.34) 1618.69(1412.08,1850.36) −0.34(−0.39,−0.29) 40.66(26.33,59.44) 3.06(1.98,4.47) 31.98(19.64,48.96) 2.42(1.49,3.70) −1.08(−1.22,−0.94)
Acute hepatitis A Islamic Republic of Afghanistan 553,327.38(502272.01,612607.53) 9928.79(9012.66,10992.50) 1,159,590.99(1086173.49,1232915.38) 6523.09(6110.09,6935.56) −1.78(−2.01,−1.55) 38,572.89(17740.92,59369.03) 692.14(318.34,1065.30) 19,983.35(10577.54,33893.68) 112.41(59.50,190.66) −6.13(−6.81,−5.45)
Acute hepatitis A Islamic Republic of Iran 1,640,964.49(1538130.57,1748304.88) 5207.83(4881.47,5548.49) 1,151,782.86(1058499.90,1235211.83) 4454.85(4094.05,4777.54) −0.36(−0.77,0.05) 13,453.65(8717.58,17850.05) 42.70(27.67,56.65) 1725.49(1203.96,2456.01) 6.67(4.66,9.50) −5.86(−6.35,−5.37)
Acute hepatitis A Islamic Republic of Mauritania 80,836.80(75662.59,86053.38) 7128.96(6672.65,7589.01) 141,181.58(133074.26,150577.02) 6053.65(5706.02,6456.51) −0.39(−0.45,−0.33) 833.98(226.53,2239.57) 73.55(19.98,197.51) 211.87(134.48,334.19) 9.08(5.77,14.33) −6.82(−7.05,−6.58)
Acute hepatitis A Islamic Republic of Pakistan 4,738,642.21(4330960.35,5208955.26) 7772.94(7104.21,8544.41) 6,275,183.60(5848132.99,6716348.31) 5745.26(5354.27,6149.16) −0.84(−1.01,−0.67) 271,075.20(161259.04,404279.15) 444.65(264.52,663.15) 104,489.92(55839.45,191603.49) 95.67(51.12,175.42) −3.99(−4.44,−3.53)
Acute hepatitis A Jamaica 53,591.74(49448.84,58057.41) 4905.38(4526.17,5314.13) 33,287.14(30263.10,36134.06) 4082.47(3711.59,4431.63) −0.45(−0.53,−0.37) 105.23(75.71,140.26) 9.63(6.93,12.84) 51.62(33.72,74.43) 6.33(4.14,9.13) −1.32(−1.41,−1.24)
Acute hepatitis A Japan 468,699.79(405222.62,528944.34) 1404.82(1214.56,1585.39) 365,491.83(319491.79,413150.29) 1721.32(1504.68,1945.77) 0.94(0.79,1.08) 1106.47(818.62,1456.02) 3.32(2.45,4.36) 562.92(357.78,827.01) 2.65(1.68,3.89) −1.40(−1.77,−1.03)
Acute hepatitis A Kingdom of Bahrain 11,290.79(10428.58,12134.38) 5642.69(5211.79,6064.28) 18,927.83(17533.14,20268.08) 4690.72(4345.09,5022.86) −0.46(−0.53,−0.39) 24.61(16.70,35.27) 12.30(8.35,17.63) 24.65(15.88,36.58) 6.11(3.94,9.06) −2.19(−2.42,−1.96)
Acute hepatitis A Kingdom of Belgium 42,346.14(37831.86,47342.49) 1713.23(1530.59,1915.37) 42,273.38(37422.42,48084.55) 1661.53(1470.86,1889.93) −0.05(−0.08,−0.02) 72.99(49.60,106.49) 2.95(2.01,4.31) 63.58(38.41,96.94) 2.50(1.51,3.81) −0.55(−0.65,−0.45)
Acute hepatitis A Kingdom of Bhutan 23,438.00(21609.69,25483.33) 6881.10(6344.33,7481.59) 13,422.99(12574.81,14289.82) 5264.42(4931.77,5604.39) −0.78(−1.03,−0.53) 1559.11(537.64,3097.55) 457.74(157.84,909.40) 115.74(57.63,223.41) 45.39(22.60,87.62) −7.85(−8.14,−7.57)
Acute hepatitis A Kingdom of Cambodia 349,600.74(322477.65,376283.11) 6140.44(5664.04,6609.09) 290,480.12(261489.51,317632.98) 4380.57(3943.37,4790.04) −1.11(−1.27,−0.94) 14,071.02(9449.34,20361.61) 247.15(165.97,357.63) 1204.41(810.50,1824.29) 18.16(12.22,27.51) −9.30(−9.78,−8.82)
Acute hepatitis A Kingdom of Denmark 12,543.96(10729.11,14179.93) 1003.29(858.14,1134.14) 12,954.86(11189.04,14671.32) 1000.99(864.55,1133.62) −0.11(−0.17,−0.05) 23.07(15.34,33.66) 1.85(1.23,2.69) 19.42(11.91,30.80) 1.50(0.92,2.38) −0.64(−0.74,−0.54)
Acute hepatitis A Kingdom of Eswatini 33,511.40(31253.75,35844.27) 7023.58(6550.41,7512.52) 33,388.07(31358.84,35472.73) 6240.69(5861.39,6630.34) −0.26(−0.31,−0.21) 327.65(177.42,564.50) 68.67(37.19,118.31) 78.08(52.03,112.73) 14.60(9.73,21.07) −4.46(−5.11,−3.81)
Acute hepatitis A Kingdom of Lesotho 57,589.72(53708.09,61303.28) 6877.86(6414.28,7321.36) 50,006.54(46567.12,53266.76) 5961.51(5551.48,6350.17) −0.38(−0.41,−0.35) 488.39(290.18,787.86) 58.33(34.66,94.09) 170.99(108.47,257.31) 20.38(12.93,30.67) −2.37(−2.87,−1.87)
Acute hepatitis A Kingdom of Morocco 752,794.97(706732.24,803895.57) 6032.09(5662.99,6441.55) 662,984.63(617462.08,707603.09) 5133.20(4780.74,5478.66) −0.44(−0.48,−0.41) 6091.86(3661.28,9531.67) 48.81(29.34,76.38) 1039.18(691.28,1506.71) 8.05(5.35,11.67) −5.89(−5.99,−5.80)
Acute hepatitis A Kingdom of Norway 17,239.43(15081.57,19502.64) 1549.55(1355.59,1752.98) 18,594.86(16165.21,21115.07) 1497.83(1302.12,1700.83) −0.15(−0.18,−0.11) 25.41(15.21,37.72) 2.28(1.37,3.39) 28.21(17.78,42.99) 2.27(1.43,3.46) 0.06(0.02,0.11)
Acute hepatitis A Kingdom of Saudi Arabia 451,602.41(417248.64,482953.61) 5499.70(5081.33,5881.50) 408,120.23(365765.17,446644.22) 4027.49(3609.51,4407.66) −0.95(−1.07,−0.83) 5900.53(3411.11,9824.29) 71.86(41.54,119.64) 557.86(364.06,853.81) 5.51(3.59,8.43) −6.81(−8.05,−5.57)
Acute hepatitis A Kingdom of Spain 167,580.63(153191.95,181512.36) 1503.36(1374.28,1628.35) 147,836.79(129004.32,168823.76) 1678.56(1464.73,1916.85) 1.00(0.74,1.25) 288.24(174.72,422.14) 2.59(1.57,3.79) 220.33(131.33,356.84) 2.50(1.49,4.05) 0.28(0.12,0.43)
Acute hepatitis A Kingdom of Sweden 21,803.90(18586.49,24898.51) 1034.82(882.12,1181.69) 21,322.40(18150.21,24656.72) 882.80(751.46,1020.85) −0.20(−0.44,0.04) 31.09(17.59,48.27) 1.48(0.83,2.29) 31.78(18.14,48.76) 1.32(0.75,2.02) −0.10(−0.45,0.24)
Acute hepatitis A Kingdom of Thailand 550,852.48(497686.78,608346.57) 2421.67(2187.94,2674.42) 416,323.41(370274.62,464735.62) 3050.39(2713.00,3405.11) 0.99(0.65,1.34) 1401.16(902.53,2005.63) 6.16(3.97,8.82) 752.06(526.05,1089.30) 5.51(3.85,7.98) 0.29(−0.08,0.66)
Acute hepatitis A Kingdom of the Netherlands 53,893.35(46967.96,61837.30) 1406.01(1225.34,1613.26) 50,032.21(43765.12,57351.64) 1355.50(1185.70,1553.80) −0.19(−0.31,−0.06) 82.54(51.54,124.13) 2.15(1.34,3.24) 71.38(42.93,111.35) 1.93(1.16,3.02) −0.31(−0.42,−0.19)
Acute hepatitis A Kingdom of Tonga 2523.81(2276.26,2778.89) 4729.58(4265.68,5207.59) 2146.76(1912.00,2371.19) 4329.67(3856.19,4782.30) −0.27(−0.37,−0.17) 93.48(53.89,151.96) 175.19(100.98,284.77) 20.34(11.60,32.26) 41.03(23.39,65.06) −4.86(−5.19,−4.53)
Acute hepatitis A Kyrgyz Republic 125,328.55(116181.72,134374.83) 5935.84(5502.63,6364.29) 154,871.52(141950.93,166352.05) 5486.40(5028.68,5893.10) −0.01(−0.18,0.17) 4080.15(3036.62,5255.24) 193.25(143.82,248.90) 341.84(243.71,478.77) 12.11(8.63,16.96) −8.52(−8.95,−8.09)
Acute hepatitis A Lao People’s Democratic Republic 117,078.15(105922.43,129201.20) 5161.08(4669.31,5695.49) 125,799.29(112989.35,138791.15) 4205.20(3776.99,4639.49) −0.76(−0.82,−0.71) 3891.08(1765.49,7080.78) 171.53(77.83,312.14) 421.09(266.17,647.94) 14.08(8.90,21.66) −8.78(−9.22,−8.34)
Acute hepatitis A Lebanese Republic 76,182.69(70912.10,81417.92) 5688.95(5295.37,6079.89) 78,076.16(71528.02,83892.67) 4685.78(4292.79,5034.86) −0.41(−0.52,−0.31) 160.58(107.56,227.18) 11.99(8.03,16.96) 103.98(68.75,154.15) 6.24(4.13,9.25) −2.10(−2.32,−1.89)
Acute hepatitis A Malaysia 377,172.82(340035.12,411388.23) 4520.84(4075.71,4930.95) 362,739.27(322076.41,406793.05) 3537.12(3140.61,3966.70) −0.74(−0.85,−0.64) 680.05(475.87,924.51) 8.15(5.70,11.08) 524.71(338.09,758.81) 5.12(3.30,7.40) −1.18(−1.37,−0.99)
Acute hepatitis A Mongolia 69,520.07(65148.42,73898.07) 6124.45(5739.33,6510.14) 75,057.54(69212.08,80518.23) 5717.80(5272.50,6133.79) 0.14(−0.06,0.35) 1097.55(420.24,2142.95) 96.69(37.02,188.79) 111.94(73.23,157.37) 8.53(5.58,11.99) −7.32(−7.87,−6.77)
Acute hepatitis A Montenegro 7976.44(7085.95,8816.61) 3718.30(3303.19,4109.96) 5200.28(4607.65,5776.20) 3457.87(3063.80,3840.82) −0.26(−0.28,−0.23) 10.67(6.71,15.57) 4.97(3.13,7.26) 6.83(4.34,10.17) 4.54(2.89,6.77) −0.35(−0.39,−0.32)
Acute hepatitis A New Zealand 16,294.03(14253.29,18425.74) 1479.81(1294.47,1673.41) 21,469.99(18492.66,24399.89) 1647.13(1418.72,1871.91) 0.39(0.29,0.48) 25.65(16.03,38.80) 2.33(1.46,3.52) 31.24(19.19,48.59) 2.40(1.47,3.73) 0.14(0.04,0.24)
Acute hepatitis A North Macedonia 28,613.88(25464.10,31118.85) 4105.67(3653.73,4465.10) 15,004.73(13314.07,16691.85) 3360.09(2981.49,3737.89) −0.69(−0.83,−0.55) 78.93(51.71,119.89) 11.33(7.42,17.20) 20.95(12.86,30.35) 4.69(2.88,6.80) −2.30(−2.75,−1.84)
Acute hepatitis A Northern Mariana Islands 647.82(581.21,720.68) 3994.81(3584.11,4444.13) 560.89(506.17,618.46) 3740.03(3375.18,4123.92) −0.51(−0.65,−0.38) 1.07(0.69,1.50) 6.60(4.27,9.24) 0.91(0.61,1.32) 6.06(4.08,8.82) −0.07(−0.34,0.21)
Acute hepatitis A Palestine 76,064.74(70642.65,81360.71) 6372.84(5918.57,6816.55) 138,886.03(130823.22,146679.44) 5768.07(5433.21,6091.73) −0.34(−0.37,−0.30) 232.20(141.88,358.65) 19.45(11.89,30.05) 143.72(95.00,209.97) 5.97(3.95,8.72) −3.55(−3.89,−3.20)
Acute hepatitis A People’s Democratic Republic of Algeria 782,401.83(736553.38,835166.58) 5788.46(5449.26,6178.83) 903,031.04(834121.23,966433.04) 5489.94(5071.00,5875.39) 0.14(−0.04,0.32) 4582.46(2505.19,8178.65) 33.90(18.53,60.51) 1200.90(805.92,1742.03) 7.30(4.90,10.59) −4.37(−4.67,−4.07)
Acute hepatitis A People’s Republic of Bangladesh 3,999,698.76(3687296.89,4347514.42) 6626.49(6108.91,7202.73) 3,092,275.24(2927289.07,3270945.92) 5070.21(4799.69,5363.17) −0.62(−0.80,−0.44) 184,519.06(126797.79,247090.79) 305.70(210.07,409.37) 21,625.39(12235.23,34242.95) 35.46(20.06,56.15) −6.37(−6.95,−5.78)
Acute hepatitis A People’s Republic of China 22,426,828.10(20826512.41,24010299.49) 5039.27(4679.68,5395.07) 12,263,623.15(10991908.01,13472902.94) 3668.41(3288.00,4030.14) −0.78(−0.97,−0.59) 400,008.25(269531.13,531488.30) 89.88(60.56,119.42) 17,810.32(11651.12,26100.20) 5.33(3.49,7.81) −9.20(−10.27,−8.11)
Acute hepatitis A Plurinational State of Bolivia 216,652.64(203532.78,230634.43) 6469.45(6077.68,6886.96) 249,235.56(232526.88,264990.34) 5481.57(5114.09,5828.08) −0.49(−0.56,−0.42) 1002.08(662.09,1421.08) 29.92(19.77,42.43) 456.83(326.64,603.16) 10.05(7.18,13.27) −3.81(−3.95,−3.67)
Acute hepatitis A Portuguese Republic 67,956.42(59959.79,76179.63) 2279.68(2011.43,2555.54) 36,332.21(31595.25,41406.37) 1895.51(1648.38,2160.24) −0.60(−0.68,−0.52) 118.14(76.06,172.85) 3.96(2.55,5.80) 54.55(32.37,83.09) 2.85(1.69,4.34) −1.13(−1.22,−1.04)
Acute hepatitis A Principality of Andorra 187.93(162.31,215.53) 1396.33(1206.01,1601.45) 181.89(156.82,208.05) 1265.08(1090.72,1446.99) −0.34(−0.45,−0.23) 2.66(1.50,4.42) 19.79(11.11,32.80) 0.62(0.39,0.92) 4.31(2.71,6.42) −4.75(−5.08,−4.42)
Acute hepatitis A Principality of Monaco 71.41(62.15,81.39) 1474.01(1282.88,1679.99) 92.36(79.58,106.64) 1364.21(1175.56,1575.14) −0.29(−0.32,−0.25) 0.10(0.06,0.16) 2.12(1.25,3.23) 0.13(0.08,0.21) 1.96(1.20,3.05) −0.16(−0.19,−0.12)
Acute hepatitis A Puerto Rico 62,160.77(57040.75,66927.35) 4666.42(4282.06,5024.25) 24,448.27(22427.40,26283.94) 3741.23(3431.98,4022.13) −0.67(−0.71,−0.63) 122.53(90.91,161.67) 9.20(6.82,12.14) 39.53(25.40,58.80) 6.05(3.89,9.00) −1.72(−1.87,−1.56)
Acute hepatitis A Republic of Albania 79,293.55(73157.93,85443.13) 5483.98(5059.63,5909.28) 30,262.06(28105.30,32536.52) 4903.75(4554.26,5272.31) −0.60(−0.77,−0.43) 324.03(227.17,462.97) 22.41(15.71,32.02) 38.31(25.92,55.96) 6.21(4.20,9.07) −3.93(−4.47,−3.39)
Acute hepatitis A Republic of Angola 644,968.49(601865.13,687501.60) 11,185.68(10438.14,11923.33) 1,129,281.43(1049388.34,1209800.63) 6046.79(5619.00,6477.93) −1.94(−2.13,−1.75) 40,024.37(9375.20,99200.38) 694.14(162.59,1720.43) 4129.16(1555.39,10225.24) 22.11(8.33,54.75) −10.65(−11.30,−10.00)
Acute hepatitis A Republic of Armenia 66,782.25(60147.77,73084.48) 5029.47(4529.81,5504.10) 32,683.15(29553.70,35633.01) 4282.83(3872.75,4669.39) −0.24(−0.47,−0.00) 204.59(148.26,289.73) 15.41(11.17,21.82) 41.51(26.59,59.79) 5.44(3.48,7.83) −2.85(−3.22,−2.47)
Acute hepatitis A Republic of Austria 31,619.23(27672.63,35811.70) 1687.98(1477.29,1911.80) 28,707.82(25057.51,32873.06) 1635.87(1427.87,1873.22) −0.16(−0.22,−0.11) 48.80(30.69,73.16) 2.61(1.64,3.91) 40.40(23.73,61.04) 2.30(1.35,3.48) −0.41(−0.51,−0.30)
Acute hepatitis A Republic of Azerbaijan 184,540.76(173178.70,196979.84) 5895.68(5532.69,6293.08) 151,021.83(139262.28,161613.61) 4956.75(4570.79,5304.39) −0.41(−0.60,−0.22) 1623.17(952.42,2485.19) 51.86(30.43,79.40) 225.80(152.81,328.38) 7.41(5.02,10.78) −6.53(−7.05,−6.01)
Acute hepatitis A Republic of Belarus 154,888.06(142070.26,166980.04) 4935.86(4527.40,5321.20) 78,200.52(69752.52,86340.92) 3861.25(3444.12,4263.19) −0.50(−0.77,−0.22) 507.45(340.44,644.83) 16.17(10.85,20.55) 123.25(83.45,173.40) 6.09(4.12,8.56) −3.33(−3.54,−3.12)
Acute hepatitis A Republic of Benin 208,796.29(195702.29,221555.51) 7275.89(6819.61,7720.51) 487,747.88(456703.42,518888.32) 6489.20(6076.17,6903.51) −0.32(−0.35,−0.29) 1477.14(789.23,2546.07) 51.47(27.50,88.72) 723.91(457.74,1137.19) 9.63(6.09,15.13) −5.45(−5.54,−5.36)
Acute hepatitis A Republic of Botswana 49,828.36(46337.15,52862.29) 6729.26(6257.78,7138.99) 55,957.97(52679.63,59513.01) 6102.25(5744.74,6489.93) −0.22(−0.28,−0.15) 257.75(166.25,403.14) 34.81(22.45,54.44) 106.54(70.60,159.56) 11.62(7.70,17.40) −2.44(−3.10,−1.79)
Acute hepatitis A Republic of Bulgaria 108,381.23(98867.86,117009.11) 4586.04(4183.49,4951.12) 62,884.55(57553.07,67597.05) 4858.62(4446.70,5222.72) 0.53(0.39,0.66) 252.15(184.98,329.57) 10.67(7.83,13.95) 81.20(54.26,118.51) 6.27(4.19,9.16) −1.29(−1.57,−1.01)
Acute hepatitis A Republic of Burundi 243,149.53(227265.52,258842.95) 7706.49(7203.05,8203.88) 496,417.19(468598.62,525892.33) 6824.04(6441.63,7229.22) −0.20(−0.29,−0.11) 2243.63(902.35,4555.34) 71.11(28.60,144.38) 1383.28(602.76,3423.03) 19.02(8.29,47.06) −3.40(−3.73,−3.07)
Acute hepatitis A Republic of Cabo Verde 12,948.73(12137.96,13770.63) 6658.42(6241.51,7081.06) 10,118.60(9561.75,10683.11) 5249.72(4960.82,5542.60) −0.70(−0.80,−0.61) 20.83(11.29,37.18) 10.71(5.81,19.12) 12.13(7.82,18.04) 6.29(4.06,9.36) −2.27(−2.54,−2.00)
Acute hepatitis A Republic of Cameroon 428,427.78(400602.93,459505.35) 7216.15(6747.49,7739.60) 1,052,813.54(995029.36,1112900.65) 6228.64(5886.78,6584.13) −0.31(−0.37,−0.24) 1031.11(547.55,1967.91) 17.37(9.22,33.15) 1159.27(756.50,1730.07) 6.86(4.48,10.24) −2.88(−3.02,−2.73)
Acute hepatitis A Republic of Chad 264,840.67(247469.40,282659.18) 7512.61(7019.85,8018.06) 758,052.68(711848.54,812603.12) 6923.13(6501.16,7421.33) −0.25(−0.28,−0.23) 2816.63(1181.95,5522.41) 79.90(33.53,156.65) 2752.94(1424.53,5329.02) 25.14(13.01,48.67) −3.55(−3.70,−3.40)
Acute hepatitis A Republic of Chile 287,952.80(265935.20,307057.32) 5459.29(5041.86,5821.49) 198,256.07(178186.60,215992.37) 4051.22(3641.11,4413.65) −0.70(−0.97,−0.43) 579.69(467.63,733.05) 10.99(8.87,13.90) 267.40(175.94,408.01) 5.46(3.60,8.34) −2.29(−2.62,−1.97)
Acute hepatitis A Republic of Colombia 848,933.97(788419.45,912928.66) 5639.70(5237.68,6064.83) 661,534.01(607427.62,717617.69) 4543.69(4172.06,4928.89) −0.82(−0.95,−0.69) 1836.99(1440.78,2376.99) 12.20(9.57,15.79) 947.88(652.75,1337.09) 6.51(4.48,9.18) −2.17(−2.32,−2.02)
Acute hepatitis A Republic of Costa Rica 79,249.24(73035.67,84753.53) 5588.21(5150.06,5976.34) 66,370.70(62022.24,70819.74) 4848.20(4530.56,5173.19) −0.31(−0.42,−0.20) 120.60(86.08,163.28) 8.50(6.07,11.51) 86.74(57.67,126.16) 6.34(4.21,9.22) −0.98(−1.07,−0.90)
Acute hepatitis A Republic of Croatia 40,891.20(36234.68,45518.40) 3082.78(2731.73,3431.63) 22,373.85(19649.85,25057.81) 2776.84(2438.76,3109.95) −0.49(−0.74,−0.23) 59.92(37.18,87.75) 4.52(2.80,6.62) 31.25(19.18,47.15) 3.88(2.38,5.85) −0.69(−0.97,−0.42)
Acute hepatitis A Republic of Cuba 177,856.48(164260.89,190985.79) 4870.08(4497.81,5229.59) 103,734.93(94451.16,112918.29) 4320.14(3933.51,4702.59) −0.41(−0.52,−0.31) 331.69(239.43,439.31) 9.08(6.56,12.03) 136.94(87.86,206.21) 5.70(3.66,8.59) −1.73(−1.83,−1.64)
Acute hepatitis A Republic of Cyprus 3579.67(3081.92,4167.24) 1381.78(1189.65,1608.59) 3747.62(3200.40,4324.68) 1314.55(1122.60,1516.97) 0.06(−0.10,0.23) 6.87(4.45,10.22) 2.65(1.72,3.95) 5.17(3.07,8.25) 1.82(1.08,2.90) −1.04(−1.15,−0.93)
Acute hepatitis A Republic of C么te d’Ivoire 488,396.89(459367.27,521212.64) 7059.29(6639.69,7533.60) 913,256.49(856319.01,971970.13) 6348.83(5953.01,6757.00) −0.17(−0.23,−0.11) 2324.03(1246.95,3886.64) 33.59(18.02,56.18) 1146.15(764.83,1677.46) 7.97(5.32,11.66) −4.40(−4.55,−4.25)
Acute hepatitis A Republic of Djibouti 15,375.93(14238.07,16399.45) 6855.89(6348.53,7312.26) 33,917.13(32033.75,35956.95) 6419.18(6062.73,6805.24) −0.09(−0.16,−0.02) 112.79(52.37,216.88) 50.29(23.35,96.71) 89.32(48.10,168.30) 16.90(9.10,31.85) −3.57(−4.01,−3.14)
Acute hepatitis A Republic of Ecuador 261,635.07(241407.10,279516.02) 5277.54(4869.51,5638.22) 353,251.39(332545.14,376753.82) 5339.13(5026.17,5694.36) −0.05(−0.08,−0.01) 651.12(505.03,825.01) 13.13(10.19,16.64) 487.06(349.52,680.85) 7.36(5.28,10.29) −2.02(−2.25,−1.80)
Acute hepatitis A Republic of El Salvador 171,494.40(160525.94,183795.60) 6223.95(5825.88,6670.39) 128,864.93(120315.85,137127.50) 5409.77(5050.88,5756.63) −0.64(−0.76,−0.51) 363.02(253.53,485.60) 13.17(9.20,17.62) 146.70(95.39,215.19) 6.16(4.00,9.03) −2.38(−2.66,−2.09)
Acute hepatitis A Republic of Equatorial Guinea 16,931.04(15858.42,18110.38) 7055.18(6608.22,7546.61) 40,176.37(37434.50,42798.39) 5216.83(4860.80,5557.29) −0.97(−1.01,−0.92) 57.55(32.74,110.48) 23.98(13.64,46.04) 49.41(32.41,74.03) 6.42(4.21,9.61) −5.01(−5.45,−4.56)
Acute hepatitis A Republic of Estonia 17,614.89(15814.22,19443.60) 3834.97(3442.94,4233.10) 9412.95(8287.50,10417.45) 3358.14(2956.63,3716.51) −0.14(−0.31,0.04) 62.15(49.58,78.11) 13.53(10.79,17.01) 13.46(8.74,19.61) 4.80(3.12,7.00) −3.13(−3.33,−2.94)
Acute hepatitis A Republic of Fiji 15,526.03(13952.73,17088.27) 4328.35(3889.75,4763.87) 14,759.74(13283.25,16265.25) 4209.50(3788.40,4638.87) 0.04(−0.04,0.12) 77.04(47.75,124.23) 21.48(13.31,34.63) 27.63(18.71,37.43) 7.88(5.34,10.67) −3.93(−4.26,−3.59)
Acute hepatitis A Republic of Finland 11,430.36(9958.87,12985.20) 900.90(784.92,1023.45) 8492.39(7306.29,9610.48) 739.42(636.15,836.77) −0.14(−0.26,−0.02) 17.59(11.08,26.93) 1.39(0.87,2.12) 13.24(7.51,20.96) 1.15(0.65,1.83) −0.33(−0.44,−0.21)
Acute hepatitis A Republic of Ghana 568,186.39(532919.19,609418.03) 6879.11(6452.12,7378.30) 996,408.55(936689.82,1053857.08) 6107.68(5741.62,6459.82) −0.32(−0.35,−0.29) 3121.93(2005.57,4745.55) 37.80(24.28,57.45) 1342.49(926.52,1894.65) 8.23(5.68,11.61) −4.76(−5.04,−4.49)
Acute hepatitis A Republic of Guatemala 345,478.16(322782.12,369882.95) 7035.12(6572.95,7532.08) 387,625.30(362517.37,412388.34) 5859.85(5480.28,6234.20) −0.70(−0.75,−0.65) 1224.67(807.85,1885.17) 24.94(16.45,38.39) 622.00(467.93,840.74) 9.40(7.07,12.71) −2.95(−3.21,−2.69)
Acute hepatitis A Republic of Guinea 246,796.05(230041.85,263996.75) 7507.83(6998.15,8031.09) 475,525.15(446785.74,507735.97) 6370.53(5985.51,6802.05) −0.45(−0.49,−0.40) 3373.03(1454.64,6784.84) 102.61(44.25,206.40) 1234.56(713.74,2083.08) 16.54(9.56,27.91) −5.36(−5.57,−5.14)
Acute hepatitis A Republic of Guinea−Bissau 41,489.80(38904.11,44098.30) 7054.94(6615.27,7498.49) 70,626.96(66413.08,75350.52) 6314.30(5937.56,6736.60) −0.21(−0.26,−0.15) 467.34(206.61,911.80) 79.47(35.13,155.04) 149.60(89.01,269.23) 13.37(7.96,24.07) −5.70(−5.89,−5.52)
Acute hepatitis A Republic of Guyana 22,247.30(20710.33,23943.74) 5830.20(5427.42,6274.78) 13,840.41(12503.43,15043.03) 4930.45(4454.17,5358.87) −0.74(−0.85,−0.64) 107.77(84.53,134.43) 28.24(22.15,35.23) 21.61(14.86,29.91) 7.70(5.30,10.66) −3.20(−3.66,−2.73)
Acute hepatitis A Republic of Haiti 211,788.71(197045.94,226906.10) 6328.81(5888.25,6780.55) 314,767.47(291167.65,337980.68) 5613.08(5192.24,6027.03) −0.29(−0.35,−0.22) 3846.96(1775.38,7387.96) 114.96(53.05,220.77) 1958.90(1104.11,3217.32) 34.93(19.69,57.37) −3.70(−3.86,−3.54)
Acute hepatitis A Republic of Honduras 157,887.21(145473.96,171258.86) 5818.38(5360.93,6311.14) 211,044.43(193210.74,228610.85) 4851.05(4441.13,5254.83) −0.61(−0.64,−0.58) 1452.45(816.03,2265.49) 53.53(30.07,83.49) 411.24(274.76,588.36) 9.45(6.32,13.52) −5.92(−6.13,−5.71)
Acute hepatitis A Republic of Iceland 696.09(610.11,786.71) 823.66(721.92,930.88) 729.03(623.73,835.88) 818.17(700.00,938.09) 0.06(−0.01,0.13) 1.04(0.66,1.63) 1.24(0.78,1.93) 1.04(0.58,1.71) 1.17(0.65,1.92) −0.19(−0.27,−0.10)
Acute hepatitis A Republic of India 36,056,184.50(32647285.98,40039820.61) 8785.27(7954.68,9755.91) 25,520,657.90(23866594.67,27078992.41) 5098.30(4767.86,5409.61) −1.78(−2.07,−1.48) 2,649,722.31(2067822.20,3358534.47) 645.62(503.84,818.32) 732,521.43(417575.04,1424020.61) 146.34(83.42,284.48) −3.99(−4.92,−3.06)
Acute hepatitis A Republic of Indonesia 4,373,157.14(4068159.41,4690662.05) 4999.99(4651.27,5363.00) 4,031,438.45(3711390.97,4343381.43) 4468.56(4113.81,4814.33) −0.29(−0.35,−0.23) 80,096.61(53609.50,112412.62) 91.58(61.29,128.53) 14,199.27(10301.50,20186.23) 15.74(11.42,22.37) −5.86(−6.03,−5.70)
Acute hepatitis A Republic of Iraq 655,895.61(613506.81,700994.18) 6368.82(5957.22,6806.74) 925,067.30(866751.52,981239.13) 5245.06(4914.41,5563.55) −0.55(−0.62,−0.47) 6846.65(4692.47,9968.83) 66.48(45.56,96.80) 1749.79(1278.42,2388.65) 9.92(7.25,13.54) −6.01(−6.20,−5.82)
Acute hepatitis A Republic of Italy 251,944.99(222454.20,282630.50) 1849.86(1633.33,2075.16) 241,206.39(212627.09,269575.77) 2301.67(2028.96,2572.39) 0.41(0.22,0.61) 433.67(270.54,625.17) 3.18(1.99,4.59) 384.52(244.24,570.20) 3.67(2.33,5.44) 0.60(0.20,1.01)
Acute hepatitis A Republic of Kazakhstan 364,441.65(336841.71,392289.85) 5486.01(5070.55,5905.22) 319,391.23(286289.18,347750.94) 4749.97(4257.67,5171.73) −0.16(−0.45,0.14) 1965.59(1208.43,2783.73) 29.59(18.19,41.90) 369.58(246.86,562.19) 5.50(3.67,8.36) −5.61(−6.41,−4.80)
Acute hepatitis A Republic of Kenya 964,569.73(896697.18,1031038.02) 6993.78(6501.65,7475.72) 1,413,204.47(1319697.96,1500113.63) 5744.63(5364.53,6097.91) −0.53(−0.62,−0.45) 9779.97(6277.42,14660.68) 70.91(45.52,106.30) 5005.51(3111.31,8026.79) 20.35(12.65,32.63) −3.37(−3.69,−3.04)
Acute hepatitis A Republic of Kiribati 2355.15(2149.25,2571.77) 6425.51(5863.77,7016.52) 2456.64(2225.55,2671.01) 4596.58(4164.19,4997.68) −1.02(−1.13,−0.92) 108.58(71.10,160.93) 296.23(193.99,439.05) 52.71(30.58,80.59) 98.63(57.22,150.80) −3.30(−3.49,−3.11)
Acute hepatitis A Republic of Korea 465,528.38(419549.04,511767.75) 2922.87(2634.18,3213.19) 210,165.56(184910.45,234918.06) 2506.97(2205.71,2802.23) −0.11(−0.38,0.17) 1427.46(992.64,2038.09) 8.96(6.23,12.80) 315.02(201.14,462.42) 3.76(2.40,5.52) −2.54(−2.77,−2.31)
Acute hepatitis A Republic of Latvia 29,248.93(25870.10,32366.99) 3887.33(3438.26,4301.73) 13,626.46(12098.48,15116.32) 3520.29(3125.54,3905.18) −0.02(−0.22,0.18) 160.86(124.51,204.57) 21.38(16.55,27.19) 21.99(15.34,31.33) 5.68(3.96,8.09) −3.76(−4.38,−3.14)
Acute hepatitis A Republic of Liberia 97,766.09(91310.89,104495.03) 7156.24(6683.73,7648.78) 169,271.26(159744.43,179485.42) 6066.99(5725.53,6433.08) −0.31(−0.41,−0.20) 816.83(402.06,1414.21) 59.79(29.43,103.52) 296.16(183.97,504.42) 10.61(6.59,18.08) −6.23(−6.60,−5.87)
Acute hepatitis A Republic of Lithuania 42,694.02(38056.87,47273.58) 3854.51(3435.86,4267.97) 18,854.39(16691.52,20891.05) 3518.97(3115.30,3899.10) −0.21(−0.38,−0.04) 95.27(72.24,130.83) 8.60(6.52,11.81) 25.46(15.91,38.16) 4.75(2.97,7.12) −1.86(−2.00,−1.71)
Acute hepatitis A Republic of Madagascar 507,879.24(474007.86,541626.50) 7551.00(7047.41,8052.75) 977,461.42(922614.29,1038915.24) 6540.93(6173.91,6952.17) −0.41(−0.47,−0.34) 5189.41(3033.73,7673.41) 77.15(45.10,114.09) 2454.37(1216.66,4654.49) 16.42(8.14,31.15) −4.60(−4.81,−4.39)
Acute hepatitis A Republic of Malawi 441,881.42(412938.28,472664.46) 7928.56(7409.24,8480.89) 656,118.09(618464.57,696791.13) 6195.14(5839.61,6579.18) −0.77(−0.90,−0.64) 9110.94(4706.77,14020.97) 163.48(84.45,251.57) 2784.93(1415.98,4968.03) 26.30(13.37,46.91) −6.35(−6.79,−5.91)
Acute hepatitis A Republic of Maldives 6521.16(5868.74,7248.88) 5081.02(4572.68,5648.03) 4865.97(4350.07,5411.23) 3734.26(3338.35,4152.70) −0.86(−1.05,−0.68) 45.15(25.59,68.82) 35.18(19.94,53.62) 7.33(4.94,10.75) 5.63(3.79,8.25) −5.54(−6.19,−4.89)
Acute hepatitis A Republic of Mali 365,274.36(341232.83,390259.34) 7385.45(6899.36,7890.62) 944,173.38(884386.59,1007268.60) 6633.65(6213.60,7076.95) −0.35(−0.38,−0.32) 889.17(488.03,2095.04) 17.98(9.87,42.36) 1185.35(747.16,1874.49) 8.33(5.25,13.17) −2.24(−2.40,−2.09)
Acute hepatitis A Republic of Malta 2360.57(2074.05,2670.99) 2048.21(1799.60,2317.56) 1635.17(1418.47,1878.84) 1947.65(1689.53,2237.87) −0.11(−0.21,−0.01) 3.69(2.28,5.46) 3.20(1.98,4.74) 2.30(1.47,3.31) 2.74(1.75,3.94) −0.47(−0.61,−0.34)
Acute hepatitis A Republic of Mauritius 19,153.09(17272.41,20723.14) 4445.79(4009.25,4810.23) 9999.30(8865.29,11093.49) 3367.85(2985.91,3736.39) −0.92(−0.98,−0.85) 40.95(31.60,52.46) 9.50(7.33,12.18) 14.40(8.84,21.65) 4.85(2.98,7.29) −2.41(−2.95,−1.86)
Acute hepatitis A Republic of Moldova 72,826.53(65613.51,79636.07) 4605.55(4149.39,5036.18) 27,036.68(24297.74,29722.91) 3883.24(3489.85,4269.06) −0.31(−0.48,−0.15) 145.04(97.87,213.76) 9.17(6.19,13.52) 38.61(24.37,56.17) 5.54(3.50,8.07) −1.61(−1.83,−1.40)
Acute hepatitis A Republic of Mozambique 570,693.10(532069.54,608176.74) 7538.18(7028.00,8033.29) 1,207,160.80(1137846.07,1278692.09) 6799.32(6408.90,7202.22) −0.38(−0.48,−0.27) 15,954.14(7070.61,29458.84) 210.74(93.39,389.12) 3646.45(1742.50,7489.22) 20.54(9.81,42.18) −7.72(−7.98,−7.47)
Acute hepatitis A Republic of Namibia 52,555.69(49056.09,55914.69) 6899.97(6440.51,7340.97) 65,945.03(61914.64,69945.35) 6155.12(5778.93,6528.49) −0.28(−0.35,−0.22) 205.93(134.10,308.09) 27.04(17.61,40.45) 113.82(78.06,158.15) 10.62(7.29,14.76) −2.36(−2.85,−1.86)
Acute hepatitis A Republic of Nauru 231.84(206.49,255.81) 4449.59(3963.10,4909.70) 216.55(193.77,240.24) 4221.95(3777.74,4683.65) −0.15(−0.17,−0.13) 0.99(0.63,1.50) 19.06(12.00,28.72) 0.47(0.32,0.68) 9.19(6.21,13.25) −2.76(−3.30,−2.22)
Acute hepatitis A Republic of Nicaragua 147,773.85(137864.14,157923.22) 6566.95(6126.57,7017.98) 140,485.57(131827.97,149696.14) 5404.83(5071.75,5759.18) −0.58(−0.68,−0.48) 929.08(628.07,1360.50) 41.29(27.91,60.46) 187.23(131.72,262.93) 7.20(5.07,10.12) −5.38(−5.71,−5.04)
Acute hepatitis A Republic of Niue 41.21(36.85,45.43) 4030.68(3604.71,4444.27) 20.20(18.13,22.13) 3825.80(3434.32,4191.42) −0.10(−0.15,−0.05) 0.13(0.08,0.19) 12.42(7.84,18.63) 0.06(0.04,0.09) 10.90(7.17,16.67) −1.77(−2.28,−1.25)
Acute hepatitis A Republic of Palau 238.93(215.03,263.31) 3875.47(3487.86,4270.95) 167.30(150.50,183.88) 3777.97(3398.68,4152.52) −0.13(−0.21,−0.05) 2.35(1.50,3.53) 38.15(24.33,57.23) 0.63(0.40,1.02) 14.29(8.96,23.00) −2.53(−2.93,−2.12)
Acute hepatitis A Republic of Panama 62,736.25(58859.07,66727.01) 5771.33(5414.65,6138.45) 79,384.13(74041.86,84894.26) 5266.88(4912.44,5632.46) −0.26(−0.28,−0.23) 126.37(96.36,166.80) 11.62(8.86,15.34) 106.80(74.69,147.11) 7.09(4.96,9.76) −1.73(−1.94,−1.52)
Acute hepatitis A Republic of Paraguay 107,601.71(98338.13,116478.44) 5200.41(4752.70,5629.43) 100,376.45(89859.36,110554.62) 3758.48(3364.68,4139.59) −1.10(−1.18,−1.03) 210.50(152.07,306.04) 10.17(7.35,14.79) 146.61(96.95,217.98) 5.49(3.63,8.16) −2.05(−2.16,−1.93)
Acute hepatitis A Republic of Peru 627,526.08(589498.43,665195.52) 5892.42(5535.35,6246.14) 674,421.83(628429.50,718891.62) 5390.84(5023.21,5746.30) −0.34(−0.40,−0.28) 1990.85(1470.32,2656.20) 18.69(13.81,24.94) 891.31(617.51,1229.61) 7.12(4.94,9.83) −3.30(−3.44,−3.15)
Acute hepatitis A Republic of Poland 436,886.10(389791.73,482257.85) 3509.27(3130.98,3873.71) 230,552.21(204299.90,255921.74) 2994.73(2653.73,3324.26) 0.03(−0.28,0.35) 673.58(447.36,954.00) 5.41(3.59,7.66) 349.26(225.59,501.00) 4.54(2.93,6.51) −0.49(−0.73,−0.26)
Acute hepatitis A Republic of Rwanda 315,055.03(294293.70,335596.89) 7612.46(7110.82,8108.80) 415,206.54(391628.76,440670.24) 6449.22(6083.00,6844.74) −0.50(−0.54,−0.46) 6495.49(3556.39,9621.32) 156.95(85.93,232.47) 1537.32(836.58,2832.36) 23.88(12.99,43.99) −6.88(−7.40,−6.36)
Acute hepatitis A Republic of San Marino 84.07(73.32,95.49) 1405.29(1225.59,1596.23) 80.98(69.75,92.06) 1297.90(1117.97,1475.49) −0.26(−0.37,−0.15) 1.24(0.81,1.86) 20.79(13.47,31.11) 0.27(0.19,0.40) 4.37(3.07,6.36) −5.54(−5.97,−5.10)
Acute hepatitis A Republic of Senegal 325,423.17(303497.52,347420.59) 7317.91(6824.86,7812.57) 506,024.07(475199.98,537218.66) 6235.43(5855.60,6619.82) −0.40(−0.46,−0.33) 803.23(442.87,1405.52) 18.06(9.96,31.61) 534.24(356.92,784.40) 6.58(4.40,9.67) −3.36(−3.74,−2.98)
Acute hepatitis A Republic of Serbia 134,480.18(123222.07,145756.28) 4635.49(4247.43,5024.18) 78,040.04(71517.47,83978.64) 4164.65(3816.57,4481.57) −0.30(−0.37,−0.23) 193.51(125.35,285.24) 6.67(4.32,9.83) 108.85(70.03,162.27) 5.81(3.74,8.66) −0.44(−0.49,−0.38)
Acute hepatitis A Republic of Seychelles 1210.20(1080.42,1355.82) 3873.67(3458.25,4339.77) 1097.13(966.84,1234.33) 3593.87(3167.07,4043.29) −0.17(−0.21,−0.13) 4.16(2.74,5.82) 13.32(8.77,18.63) 1.69(1.13,2.45) 5.53(3.69,8.04) −2.15(−2.42,−1.89)
Acute hepatitis A Republic of Sierra Leone 163,423.87(152681.35,174675.32) 7409.14(6922.11,7919.25) 285,849.56(268262.29,305687.38) 6281.49(5895.02,6717.43) −0.52(−0.54,−0.49) 2425.47(917.67,4674.79) 109.96(41.60,211.94) 546.16(335.44,839.07) 12.00(7.37,18.44) −7.06(−7.30,−6.82)
Acute hepatitis A Republic of Singapore 16,897.38(14976.77,18962.59) 1834.74(1626.19,2058.98) 21,798.46(18936.01,24928.97) 2089.18(1814.84,2389.21) 0.11(−0.06,0.29) 27.92(18.26,41.13) 3.03(1.98,4.47) 26.14(15.80,40.68) 2.51(1.51,3.90) −1.11(−1.34,−0.88)
Acute hepatitis A Republic of Slovenia 18,604.63(16660.55,20718.01) 3341.51(2992.34,3721.09) 13,387.19(11844.66,14888.52) 3306.93(2925.89,3677.79) 0.23(0.13,0.33) 32.47(22.37,45.56) 5.83(4.02,8.18) 17.76(11.18,26.45) 4.39(2.76,6.53) −0.78(−0.93,−0.64)
Acute hepatitis A Republic of South Africa 1,110,816.09(1031887.09,1194048.76) 6303.68(5855.77,6776.01) 1,148,347.91(1069980.36,1222134.82) 5765.38(5371.93,6135.83) −0.04(−0.16,0.09) 3420.26(2593.00,4676.59) 19.41(14.71,26.54) 1581.83(1181.11,2102.49) 7.94(5.93,10.56) −2.26(−2.84,−1.68)
Acute hepatitis A Republic of South Sudan 241,993.95(224750.50,258069.33) 7364.24(6839.50,7853.44) 376,020.47(350444.89,400863.90) 6852.50(6386.42,7305.24) −0.24(−0.35,−0.13) 3235.97(1745.92,5051.91) 98.48(53.13,153.74) 3072.02(1485.84,5281.70) 55.98(27.08,96.25) −1.23(−1.70,−0.75)
Acute hepatitis A Republic of Sudan 953,731.01(866679.05,1038066.17) 8634.08(7846.00,9397.56) 1,226,425.07(1154862.30,1305072.44) 5737.64(5402.85,6105.58) −1.10(−1.21,−0.98) 67,208.41(39522.43,99664.63) 608.43(357.79,902.26) 9196.71(4308.01,16366.22) 43.03(20.15,76.57) −8.14(−8.50,−7.78)
Acute hepatitis A Republic of Suriname 9217.82(8568.37,9797.26) 5390.83(5011.01,5729.70) 8738.65(7989.95,9474.37) 4602.85(4208.49,4990.37) −0.48(−0.51,−0.45) 18.52(13.27,25.02) 10.83(7.76,14.63) 11.68(8.07,17.13) 6.15(4.25,9.02) −1.95(−2.15,−1.75)
Acute hepatitis A Republic of Tajikistan 188,956.86(175586.25,202642.87) 6573.60(6108.45,7049.72) 274,531.23(255849.28,293538.45) 6162.13(5742.80,6588.77) −0.17(−0.32,−0.01) 4022.14(1696.71,7260.89) 139.93(59.03,252.60) 821.54(437.54,1723.63) 18.44(9.82,38.69) −6.15(−6.87,−5.43)
Acute hepatitis A Republic of the Congo 86,068.37(80814.85,91648.52) 6487.48(6091.49,6908.09) 136,552.60(127737.10,145288.54) 5491.00(5136.52,5842.29) −0.33(−0.46,−0.20) 2439.83(447.42,7852.91) 183.90(33.72,591.92) 322.32(162.14,680.81) 12.96(6.52,27.38) −8.61(−9.19,−8.03)
Acute hepatitis A Republic of the Gambia 39,309.77(36704.46,42265.53) 6997.22(6533.47,7523.35) 76,775.08(72516.41,81444.65) 6061.43(5725.20,6430.09) −0.39(−0.47,−0.32) 74.62(41.03,130.98) 13.28(7.30,23.32) 81.79(51.34,117.79) 6.46(4.05,9.30) −2.27(−2.60,−1.93)
Acute hepatitis A Republic of the Marshall Islands 1611.13(1512.26,1714.73) 6015.72(5646.56,6402.54) 1243.38(1163.08,1328.22) 5389.14(5041.08,5756.84) −0.26(−0.33,−0.20) 5.61(3.11,9.05) 20.96(11.62,33.81) 2.20(1.49,3.14) 9.55(6.44,13.61) −2.98(−3.20,−2.75)
Acute hepatitis A Republic of the Niger 361,945.59(338291.06,386554.70) 7460.34(6972.78,7967.58) 1,065,382.95(1000155.19,1137463.05) 6835.18(6416.70,7297.62) −0.28(−0.36,−0.21) 5260.39(1957.81,11241.03) 108.43(40.35,231.70) 2136.89(1164.34,4120.36) 13.71(7.47,26.44) −6.58(−6.85,−6.32)
Acute hepatitis A Republic of the Philippines 1,356,295.05(1224775.16,1494129.93) 4231.47(3821.14,4661.49) 1,674,897.36(1517406.05,1840361.67) 3740.47(3388.75,4109.99) −0.39(−0.41,−0.37) 24,499.22(18253.51,32363.55) 76.43(56.95,100.97) 2835.34(2010.42,3913.00) 6.33(4.49,8.74) −8.28(−9.14,−7.41)
Acute hepatitis A Republic of the Union of Myanmar 845,074.81(762796.45,931720.16) 4421.87(3991.35,4875.24) 800,992.08(716010.22,893857.39) 3856.83(3447.64,4303.98) −0.45(−0.48,−0.41) 9177.22(4304.20,18437.96) 48.02(22.52,96.48) 2579.39(1624.02,4162.84) 12.42(7.82,20.04) −4.94(−5.29,−4.59)
Acute hepatitis A Republic of Trinidad and Tobago 26,230.18(24157.54,28215.54) 5049.38(4650.39,5431.56) 15,066.95(13618.57,16362.23) 4139.46(3741.53,4495.32) −0.35(−0.50,−0.20) 58.72(43.84,75.71) 11.30(8.44,14.57) 23.71(16.14,32.38) 6.52(4.43,8.90) −2.03(−2.20,−1.86)
Acute hepatitis A Republic of Tunisia 231,206.29(217819.35,246069.67) 5794.56(5459.06,6167.07) 184,901.97(171772.35,196980.34) 5156.85(4790.67,5493.71) −0.08(−0.24,0.08) 1403.04(752.95,2596.32) 35.16(18.87,65.07) 236.74(158.71,349.70) 6.60(4.43,9.75) −4.43(−5.19,−3.66)
Acute hepatitis A Republic of Turkey 1,386,967.79(1298748.85,1480110.09) 5198.21(4867.58,5547.30) 1,018,358.10(924596.24,1105814.20) 4120.87(3741.46,4474.77) −0.76(−1.05,−0.47) 21,956.54(12932.42,34492.21) 82.29(48.47,129.27) 1467.91(971.29,2158.42) 5.94(3.93,8.73) −9.67(−10.81,−8.51)
Acute hepatitis A Republic of Uganda 839,091.97(781823.85,891371.26) 8148.28(7592.15,8655.95) 1,730,554.28(1617129.61,1831483.61) 6937.89(6483.16,7342.52) −0.54(−0.56,−0.51) 13,426.64(5505.22,25221.17) 130.38(53.46,244.92) 6316.25(2790.60,13487.21) 25.32(11.19,54.07) −5.54(−5.83,−5.23)
Acute hepatitis A Republic of Uzbekistan 749,811.69(699801.41,803293.91) 7023.46(6555.02,7524.43) 776,094.83(721283.17,831840.97) 6154.53(5719.87,6596.61) −0.22(−0.49,0.06) 37,978.41(28998.60,48875.61) 355.74(271.63,457.82) 1491.53(1132.58,1945.85) 11.83(8.98,15.43) −10.76(−11.21,−10.31)
Acute hepatitis A Republic of Vanuatu 4145.45(3757.32,4569.10) 4967.69(4502.58,5475.38) 7087.19(6367.39,7740.81) 4806.87(4318.67,5250.19) −0.05(−0.09,−0.02) 28.51(12.21,55.96) 34.16(14.63,67.06) 18.78(10.73,31.00) 12.74(7.28,21.03) −3.33(−3.54,−3.11)
Acute hepatitis A Republic of Yemen 783,994.35(708743.12,868302.43) 9324.29(8429.30,10326.99) 968,803.24(904610.82,1030021.94) 5544.86(5177.46,5895.24) −1.50(−1.62,−1.39) 50,076.13(24787.57,87647.74) 595.57(294.81,1042.42) 5861.16(3246.42,10076.68) 33.55(18.58,57.67) −9.60(−10.03,−9.16)
Acute hepatitis A Republic of Zambia 352,584.07(329472.33,377107.32) 7501.00(7009.32,8022.72) 687,239.01(649168.40,728710.46) 6573.79(6209.63,6970.49) −0.40(−0.48,−0.32) 7724.64(4183.40,12884.34) 164.34(89.00,274.11) 2138.63(1174.06,3710.23) 20.46(11.23,35.49) −6.84(−7.30,−6.39)
Acute hepatitis A Republic of Zimbabwe 408,064.07(383512.64,433146.72) 6775.81(6368.14,7192.30) 519,124.85(486339.71,551413.70) 6501.87(6091.25,6906.28) 0.07(0.00,0.15) 2824.10(1042.56,6461.07) 46.89(17.31,107.28) 2303.30(1312.06,3973.31) 28.85(16.43,49.76) 1.22(0.07,2.38)
Acute hepatitis A Romania 273,892.65(247976.61,300721.88) 3650.51(3305.09,4008.09) 117,921.73(104540.57,130346.85) 2918.23(2587.08,3225.71) −0.63(−0.71,−0.55) 570.66(394.09,793.43) 7.61(5.25,10.57) 183.45(118.04,265.58) 4.54(2.92,6.57) −1.85(−2.06,−1.65)
Acute hepatitis A Russian Federation 1,833,815.25(1658502.80,2002332.44) 4058.46(3670.47,4431.41) 1,355,552.68(1229226.56,1469817.36) 4011.73(3637.87,4349.90) 0.04(−0.12,0.19) 2877.76(2009.83,4052.50) 6.37(4.45,8.97) 1860.37(1208.37,2789.63) 5.51(3.58,8.26) −1.18(−1.44,−0.92)
Acute hepatitis A Saint Kitts and Nevis 938.42(863.80,1004.32) 5108.13(4701.95,5466.83) 590.30(532.60,638.43) 4197.85(3787.48,4540.08) −0.70(−0.77,−0.64) 2.20(1.62,2.99) 11.97(8.80,16.29) 0.84(0.56,1.22) 6.00(4.00,8.70) −2.43(−2.57,−2.29)
Acute hepatitis A Saint Lucia 3559.37(3297.56,3811.39) 5330.26(4938.20,5707.67) 1771.56(1602.83,1920.14) 4222.20(3820.06,4576.31) −0.82(−0.92,−0.72) 6.80(5.04,9.12) 10.18(7.55,13.65) 2.43(1.54,3.51) 5.78(3.67,8.38) −1.93(−2.05,−1.81)
Acute hepatitis A Saint Vincent and the Grenadines 2814.11(2628.14,2981.22) 5235.28(4889.31,5546.17) 1491.23(1359.99,1607.04) 4424.45(4035.06,4768.08) −0.52(−0.56,−0.48) 3.34(2.17,4.97) 6.21(4.03,9.24) 1.97(1.23,2.93) 5.85(3.64,8.70) −0.77(−1.25,−0.29)
Acute hepatitis A Slovak Republic 61,077.75(54022.22,68185.19) 3479.80(3077.82,3884.73) 37,812.78(33314.31,42237.79) 3372.82(2971.57,3767.53) 0.08(−0.04,0.21) 94.85(60.90,135.42) 5.40(3.47,7.72) 49.64(31.05,74.50) 4.43(2.77,6.65) −0.65(−0.71,−0.59)
Acute hepatitis A Socialist Republic of Viet Nam 1,847,233.13(1706054.82,1993390.75) 5486.79(5067.45,5920.92) 1,378,123.65(1225212.65,1516038.11) 4358.54(3874.94,4794.72) −0.61(−0.80,−0.42) 9259.86(6278.22,12736.36) 27.50(18.65,37.83) 1891.27(1277.16,2686.00) 5.98(4.04,8.49) −4.88(−5.26,−4.51)
Acute hepatitis A Solomon Islands 9472.93(8542.02,10334.02) 4867.47(4389.14,5309.93) 15,529.71(14039.17,16954.29) 4695.41(4244.74,5126.13) −0.08(−0.10,−0.06) 145.05(45.06,353.39) 74.53(23.15,181.58) 55.35(26.20,107.77) 16.74(7.92,32.58) −4.73(−4.84,−4.61)
Acute hepatitis A State of Eritrea 146,696.61(136444.87,156331.16) 7458.69(6937.44,7948.55) 214,841.45(202146.19,228154.84) 6679.05(6284.38,7092.94) −0.32(−0.35,−0.28) 1860.49(946.00,2993.58) 94.60(48.10,152.21) 874.96(398.87,1752.49) 27.20(12.40,54.48) −3.74(−3.96,−3.52)
Acute hepatitis A State of Israel 37,961.69(33349.59,43395.18) 1892.11(1662.23,2162.93) 58,654.57(50675.56,66409.82) 1738.73(1502.20,1968.62) −0.56(−0.71,−0.42) 56.01(34.66,84.08) 2.79(1.73,4.19) 76.65(47.00,119.88) 2.27(1.39,3.55) −1.04(−1.20,−0.87)
Acute hepatitis A State of Kuwait 37,519.88(34627.01,39932.75) 5469.73(5048.00,5821.48) 52,153.66(48018.91,56018.50) 4760.88(4383.43,5113.68) −0.35(−0.42,−0.28) 39.86(25.36,58.15) 5.81(3.70,8.48) 62.59(38.59,92.05) 5.71(3.52,8.40) −0.16(−0.23,−0.10)
Acute hepatitis A State of Libya 128,747.02(119939.68,136811.98) 5577.60(5196.04,5926.99) 94,731.25(88211.05,100323.92) 4537.97(4225.62,4805.87) −0.58(−0.62,−0.54) 553.96(276.39,974.89) 24.00(11.97,42.23) 168.42(110.46,238.92) 8.07(5.29,11.44) −2.96(−3.51,−2.41)
Acute hepatitis A State of Qatar 8962.42(8247.66,9683.65) 5854.76(5387.84,6325.90) 31,757.92(28858.82,34303.15) 5318.76(4833.22,5745.03) −0.13(−0.21,−0.05) 17.70(12.57,25.10) 11.56(8.21,16.40) 34.21(23.01,50.65) 5.73(3.85,8.48) −2.23(−2.44,−2.01)
Acute hepatitis A Sultanate of Oman 62,693.57(58285.55,67252.39) 6255.00(5815.20,6709.83) 78,061.81(71581.64,83998.67) 5232.61(4798.24,5630.57) −0.32(−0.55,−0.09) 1152.03(798.92,1634.63) 114.94(79.71,163.09) 199.36(150.30,262.32) 13.36(10.07,17.58) −5.23(−6.22,−4.24)
Acute hepatitis A Swiss Confederation 18,399.12(15928.36,20908.09) 1166.59(1009.93,1325.67) 21,024.48(18062.46,23925.69) 1192.82(1024.77,1357.42) 0.11(0.07,0.14) 42.07(30.52,57.01) 2.67(1.94,3.61) 33.02(21.46,48.96) 1.87(1.22,2.78) −1.35(−1.59,−1.12)
Acute hepatitis A Syrian Arab Republic 459,886.23(430381.67,490806.07) 6255.31(5854.00,6675.88) 245,075.65(231869.64,257675.31) 4504.98(4262.23,4736.59) −1.01(−1.13,−0.90) 3488.96(2449.08,4876.22) 47.46(33.31,66.33) 406.24(281.63,557.92) 7.47(5.18,10.26) −5.67(−6.53,−4.81)
Acute hepatitis A Taiwan (Province of China) 250,778.85(224712.27,277617.56) 3431.12(3074.48,3798.32) 121,263.92(107024.25,136232.72) 2997.53(2645.54,3367.55) −0.40(−0.78,−0.02) 349.75(218.26,522.05) 4.79(2.99,7.14) 168.72(101.67,257.44) 4.17(2.51,6.36) −0.34(−0.66,−0.02)
Acute hepatitis A Togolese Republic 148,374.83(139044.70,157660.47) 6892.42(6459.01,7323.77) 254,547.47(240124.97,270414.99) 6096.35(5750.93,6476.37) −0.28(−0.35,−0.21) 294.28(163.22,526.45) 13.67(7.58,24.46) 291.54(189.68,434.34) 6.98(4.54,10.40) −2.13(−2.24,−2.02)
Acute hepatitis A Tokelau 32.52(29.23,35.53) 4287.59(3854.51,4684.42) 19.48(17.57,21.18) 3807.31(3433.70,4139.97) −0.37(−0.45,−0.28) 0.14(0.07,0.25) 18.21(9.52,32.68) 0.08(0.05,0.13) 16.42(10.12,26.15) −2.52(−3.36,−1.68)
Acute hepatitis A Turkmenistan 130,795.89(120911.85,140761.74) 6937.92(6413.63,7466.54) 104,338.04(96412.08,112971.71) 5321.87(4917.59,5762.24) −0.66(−0.79,−0.53) 5463.51(3254.11,8064.64) 289.81(172.61,427.78) 316.84(206.59,466.10) 16.16(10.54,23.77) −9.03(−9.41,−8.65)
Acute hepatitis A Tuvalu 207.97(186.74,230.25) 4866.91(4370.13,5388.45) 206.54(185.95,228.09) 4204.17(3784.91,4642.81) −0.49(−0.59,−0.40) 1.50(0.78,2.61) 35.15(18.21,61.06) 0.41(0.28,0.57) 8.28(5.67,11.52) −4.68(−4.95,−4.42)
Acute hepatitis A Ukraine 546,542.72(486257.40,602762.38) 3631.11(3230.58,4004.62) 280,072.68(250368.14,307118.77) 3316.34(2964.61,3636.60) 0.31(0.03,0.60) 983.42(680.18,1385.08) 6.53(4.52,9.20) 442.72(286.02,656.89) 5.24(3.39,7.78) −0.69(−0.85,−0.54)
Acute hepatitis A Union of the Comoros 19,410.17(18096.90,20625.34) 7343.50(6846.65,7803.24) 19,600.31(18390.93,20743.89) 6243.17(5857.96,6607.43) −0.55(−0.56,−0.53) 147.35(69.09,251.44) 55.75(26.14,95.13) 58.20(31.39,107.54) 18.54(10.00,34.25) −3.77(−4.03,−3.52)
Acute hepatitis A United Arab Emirates 40,409.62(37081.41,43647.04) 5715.50(5244.76,6173.39) 83,185.46(76459.26,89652.42) 4907.46(4510.65,5288.97) −0.13(−0.34,0.07) 68.63(45.00,103.28) 9.71(6.36,14.61) 104.66(70.09,153.98) 6.17(4.13,9.08) −1.15(−1.32,−0.98)
Acute hepatitis A United Kingdom of Great Britain and Northern Ireland 262,373.06(230628.16,294745.80) 1768.73(1554.73,1986.97) 250,628.57(218095.50,283334.33) 1600.98(1393.16,1809.90) −0.24(−0.34,−0.14) 386.07(240.54,558.99) 2.60(1.62,3.77) 377.38(238.56,579.58) 2.41(1.52,3.70) −0.31(−0.43,−0.18)
Acute hepatitis A United Mexican States 2,642,915.25(2474159.13,2809289.48) 6094.28(5705.14,6477.92) 2,228,683.07(2119671.10,2352469.50) 5164.87(4912.24,5451.74) −0.41(−0.59,−0.23) 13,635.45(11747.49,15864.18) 31.44(27.09,36.58) 3987.80(3043.83,5246.63) 9.24(7.05,12.16) −3.65(−4.01,−3.29)
Acute hepatitis A United Republic of Tanzania 1,111,647.96(1034605.18,1183320.33) 7449.11(6932.85,7929.39) 2,031,331.58(1917114.58,2158274.97) 6582.78(6212.65,6994.16) −0.37(−0.43,−0.32) 19,791.34(9618.64,31589.56) 132.62(64.45,211.68) 7093.32(3749.96,13056.57) 22.99(12.15,42.31) −5.37(−5.59,−5.15)
Acute hepatitis A United States of America 1,446,698.05(1269455.62,1634262.94) 1953.80(1714.43,2207.11) 1,591,569.36(1390885.34,1783680.57) 1957.35(1710.55,2193.62) −0.18(−0.30,−0.07) 2378.62(1583.93,3289.58) 3.21(2.14,4.44) 2553.92(1626.90,3747.61) 3.14(2.00,4.61) −0.54(−0.72,−0.37)
Acute hepatitis A United States Virgin Islands 2087.17(1912.35,2253.06) 5003.40(4584.32,5401.09) 753.15(682.19,817.48) 4133.77(3744.30,4486.85) −0.63(−0.65,−0.60) 2.85(1.94,4.14) 6.82(4.64,9.92) 1.02(0.63,1.53) 5.60(3.46,8.42) −0.66(−0.73,−0.59)
Acute hepatitis B American Samoa 282.78(218.64,355.43) 1181.87(913.81,1485.51) 53.70(41.85,69.01) 280.71(218.76,360.77) −0.03(−0.08,0.01) 1.13(0.79,1.64) 4.73(3.32,6.84) 0.53(0.32,0.78) 2.75(1.69,4.08) −1.99(−2.19,−1.80)
Acute hepatitis B Antigua and Barbuda 74.67(54.63,97.92) 312.55(228.66,409.87) 5.91(4.33,7.78) 25.30(18.52,33.29) −0.22(−0.24,−0.20) 0.31(0.20,0.45) 1.28(0.84,1.90) 0.10(0.08,0.13) 0.44(0.33,0.55) −3.83(−4.45,−3.20)
Acute hepatitis B Arab Republic of Egypt 367,737.14(279262.94,484910.76) 1316.98(1000.13,1736.62) 41,078.91(31475.14,52495.76) 88.25(67.62,112.77) −0.30(−0.33,−0.26) 35,897.84(8903.39,72006.62) 128.56(31.89,257.88) 10,230.30(4287.45,19180.21) 21.98(9.21,41.20) −4.66(−5.37,−3.95)
Acute hepatitis B Argentine Republic 19,553.70(15313.53,24548.29) 150.10(117.55,188.44) 4162.42(3211.06,5268.96) 30.36(23.42,38.43) −0.36(−0.39,−0.32) 249.83(160.34,478.78) 1.92(1.23,3.68) 46.74(33.48,62.55) 0.34(0.24,0.46) −5.62(−6.04,−5.20)
Acute hepatitis B Australia 34,234.18(26618.90,42436.81) 661.91(514.67,820.50) 4599.44(3697.23,5814.60) 73.73(59.27,93.21) −0.51(−0.56,−0.45) 41.92(30.41,58.87) 0.81(0.59,1.14) 15.52(12.58,19.28) 0.25(0.20,0.31) −4.81(−5.32,−4.29)
Acute hepatitis B Barbados 226.63(161.81,307.01) 266.92(190.58,361.60) 27.27(19.91,37.55) 41.08(29.99,56.57) −0.66(−0.95,−0.37) 2.26(1.41,3.59) 2.66(1.66,4.23) 1.58(1.03,2.38) 2.39(1.56,3.59) −0.10(−0.61,0.40)
Acute hepatitis B Belize 395.84(287.01,544.17) 385.90(279.81,530.50) 143.52(104.69,201.05) 84.90(61.93,118.93) −0.80(−1.17,−0.43) 2.37(1.49,3.92) 2.31(1.45,3.82) 0.81(0.62,1.05) 0.48(0.36,0.62) −5.61(−6.17,−5.05)
Acute hepatitis B Bermuda 39.98(29.59,54.73) 251.43(186.10,344.18) 3.92(2.76,5.45) 34.11(23.99,47.40) −0.86(−1.09,−0.63) 0.06(0.04,0.10) 0.38(0.26,0.60) 0.02(0.01,0.04) 0.20(0.13,0.31) −2.41(−2.82,−1.99)
Acute hepatitis B Bolivarian Republic of Venezuela 32,455.88(23041.91,43828.40) 357.60(253.88,482.90) 9294.51(6608.18,12561.10) 106.20(75.51,143.53) −1.16(−1.47,−0.85) 108.74(67.59,174.95) 1.20(0.74,1.93) 249.56(133.04,421.16) 2.85(1.52,4.81) 3.19(2.45,3.95)
Acute hepatitis B Bosnia and Herzegovina 5507.34(4414.63,6983.19) 371.68(297.93,471.28) 485.05(388.21,611.76) 72.93(58.37,91.98) −1.35(−1.63,−1.07) 96.24(47.67,181.60) 6.50(3.22,12.26) 16.65(8.54,28.57) 2.50(1.28,4.30) −2.84(−3.06,−2.61)
Acute hepatitis B Brunei Darussalam 573.16(427.78,785.08) 498.29(371.90,682.52) 83.04(60.77,113.29) 64.30(47.06,87.73) −1.42(−1.69,−1.16) 64.29(36.94,101.31) 55.89(32.12,88.07) 8.26(4.20,15.18) 6.40(3.25,11.76) −8.22(−8.95,−7.49)
Acute hepatitis B Burkina Faso 113,721.17(85719.26,147717.58) 2010.20(1515.22,2611.13) 38,732.07(29589.51,48819.53) 302.46(231.06,381.23) −1.47(−1.66,−1.27) 8682.45(4154.72,13978.17) 153.48(73.44,247.09) 8166.22(3970.72,15724.76) 63.77(31.01,122.79) −2.52(−3.14,−1.89)
Acute hepatitis B Canada 44,093.24(35020.72,53701.14) 575.28(456.91,700.63) 18,123.13(14217.44,23487.42) 220.24(172.78,285.43) −1.56(−1.73,−1.39) 79.02(62.03,100.89) 1.03(0.81,1.32) 23.08(16.51,32.50) 0.28(0.20,0.39) −4.46(−4.78,−4.14)
Acute hepatitis B Central African Republic 33,382.41(24168.87,44922.64) 2229.74(1614.33,3000.56) 40,760.49(29952.36,51337.49) 1408.45(1034.98,1773.92) −1.59(−1.90,−1.28) 3870.28(756.94,13083.60) 258.51(50.56,873.91) 1714.25(657.37,4363.77) 59.23(22.71,150.79) −4.48(−4.71,−4.26)
Acute hepatitis B Commonwealth of Dominica 114.66(85.47,155.84) 349.87(260.79,475.51) 13.69(9.25,19.62) 70.47(47.62,101.00) −1.67(−2.01,−1.33) 0.64(0.38,1.08) 1.94(1.17,3.28) 0.29(0.19,0.45) 1.51(0.96,2.29) −0.72(−1.02,−0.42)
Acute hepatitis B Commonwealth of the Bahamas 356.78(270.30,468.43) 331.39(251.06,435.10) 53.68(40.01,68.42) 46.57(34.71,59.35) −1.83(−2.10,−1.57) 1.07(0.76,1.49) 0.99(0.71,1.38) 0.44(0.33,0.60) 0.38(0.28,0.52) −3.42(−4.51,−2.31)
Acute hepatitis B Cook Islands 73.87(54.70,96.86) 857.92(635.25,1124.87) 4.30(3.24,5.71) 83.04(62.46,110.08) −1.85(−2.02,−1.68) 0.10(0.06,0.15) 1.17(0.74,1.72) 0.01(0.00,0.02) 0.21(0.08,0.40) −6.74(−7.12,−6.36)
Acute hepatitis B Czech Republic 10,136.56(7749.73,13299.00) 333.01(254.60,436.91) 454.59(335.27,599.55) 20.47(15.10,27.00) −2.00(−2.28,−1.71) 25.23(19.31,32.88) 0.83(0.63,1.08) 5.75(3.76,8.67) 0.26(0.17,0.39) −3.43(−5.39,−1.43)
Acute hepatitis B Democratic People’s Republic of Korea 184,940.01(142545.37,239209.04) 2374.27(1830.00,3070.98) 27,564.63(20942.69,35223.04) 417.50(317.20,533.50) −2.17(−2.56,−1.77) 3804.84(1722.68,7301.10) 48.85(22.12,93.73) 153.38(88.52,275.28) 2.32(1.34,4.17) −9.68(−10.08,−9.27)
Acute hepatitis B Democratic Republic of Sao Tome and Principe 1382.39(1050.88,1751.88) 1978.12(1503.75,2506.84) 336.01(240.74,460.13) 330.06(236.47,451.98) −2.21(−2.58,−1.83) 33.82(21.55,50.02) 48.40(30.83,71.58) 3.73(2.28,6.06) 3.67(2.24,5.95) −8.09(−8.55,−7.63)
Acute hepatitis B Democratic Republic of the Congo 612,922.33(438553.00,804494.75) 2831.03(2025.63,3715.88) 690,373.83(533599.20,897770.33) 1441.07(1113.82,1873.99) −2.23(−2.58,−1.87) 3145.91(1410.62,7608.55) 14.53(6.52,35.14) 2669.10(1280.30,4548.61) 5.57(2.67,9.49) −2.64(−3.20,−2.08)
Acute hepatitis B Democratic Republic of Timor−Leste 4375.32(2969.31,6035.36) 1075.91(730.16,1484.11) 3307.56(2311.05,4574.03) 482.55(337.17,667.32) −2.28(−2.53,−2.02) 22.65(5.86,81.86) 5.57(1.44,20.13) 13.96(5.33,31.15) 2.04(0.78,4.55) −4.23(−4.66,−3.79)
Acute hepatitis B Democratic Socialist Republic of Sri Lanka 48,534.20(38636.51,61806.72) 670.35(533.64,853.67) 3353.80(2680.97,4224.00) 48.61(38.86,61.22) −2.30(−2.70,−1.90) 237.22(156.81,345.96) 3.28(2.17,4.78) 35.75(18.93,56.34) 0.52(0.27,0.82) −6.81(−7.40,−6.22)
Acute hepatitis B Dominican Republic 13,939.32(10562.21,18268.02) 398.02(301.59,521.62) 5228.69(4029.43,6809.25) 134.39(103.57,175.01) −2.30(−3.06,−1.53) 114.05(67.14,185.78) 3.26(1.92,5.30) 114.64(58.18,210.14) 2.95(1.50,5.40) −1.57(−2.12,−1.02)
Acute hepatitis B Eastern Republic of Uruguay 1398.38(1091.02,1788.97) 129.84(101.30,166.10) 153.39(113.43,200.84) 16.98(12.56,22.23) −2.36(−2.63,−2.08) 5.46(3.59,7.49) 0.51(0.33,0.70) 0.68(0.50,0.91) 0.08(0.06,0.10) −7.33(−7.95,−6.71)
Acute hepatitis B Federal Democratic Republic of Ethiopia 481,451.97(366073.22,627007.26) 1633.86(1242.31,2127.81) 465,946.89(343219.68,609791.04) 814.62(600.06,1066.11) −2.44(−2.86,−2.01) 15,099.91(3725.02,39814.68) 51.24(12.64,135.12) 19,368.76(6427.57,33186.12) 33.86(11.24,58.02) −1.75(−2.03,−1.46)
Acute hepatitis B Federal Democratic Republic of Nepal 32,559.21(28209.85,38311.43) 314.62(272.59,370.20) 8622.25(7192.86,10518.36) 69.23(57.75,84.45) −2.45(−2.52,−2.37) 2316.43(348.75,8240.32) 22.38(3.37,79.63) 3051.90(801.65,6693.13) 24.50(6.44,53.74) 0.84(0.58,1.10)
Acute hepatitis B Federal Republic of Germany 24,440.68(19091.36,30645.49) 141.03(110.16,176.83) 2966.73(2282.92,3786.19) 18.60(14.32,23.74) −2.56(−2.94,−2.19) 198.42(151.17,258.01) 1.14(0.87,1.49) 9.39(6.89,12.56) 0.06(0.04,0.08) −10.02(−10.58,−9.45)
Acute hepatitis B Federal Republic of Nigeria 1,475,659.84(1146532.37,1883930.44) 3041.41(2363.06,3882.87) 1,972,269.42(1559495.76,2495737.84) 1543.58(1220.53,1953.27) −2.60(−2.95,−2.25) 306,090.56(104274.02,543208.72) 630.87(214.91,1119.58) 101,828.94(53580.60,167249.53) 79.70(41.93,130.90) −7.12(−7.85,−6.38)
Acute hepatitis B Federal Republic of Somalia 135,182.21(101580.39,175789.69) 2856.56(2146.51,3714.65) 314,888.34(238817.21,395304.96) 2463.07(1868.04,3092.09) −2.83(−3.23,−2.43) 9321.51(2561.10,18916.91) 196.97(54.12,399.74) 20,460.74(7668.42,37589.82) 160.04(59.98,294.03) −0.54(−0.81,−0.26)
Acute hepatitis B Federated States of Micronesia 782.91(608.70,1022.10) 1361.63(1058.65,1777.64) 177.09(138.44,225.38) 427.29(334.04,543.80) −2.87(−3.22,−2.51) 10.56(4.14,20.23) 18.36(7.20,35.18) 1.39(0.60,2.58) 3.36(1.46,6.22) −5.81(−6.05,−5.57)
Acute hepatitis B Federative Republic of Brazil 425,599.48(335964.49,539247.20) 633.40(500.00,802.54) 53,608.02(39356.42,71280.02) 83.87(61.57,111.52) −2.90(−3.10,−2.71) 2009.90(1704.52,2473.46) 2.99(2.54,3.68) 711.66(582.83,869.71) 1.11(0.91,1.36) −3.53(−4.46,−2.59)
Acute hepatitis B French Republic 35,568.61(28248.23,43622.68) 220.35(175.00,270.24) 10,022.14(7424.64,13661.60) 63.63(47.14,86.73) −2.93(−3.43,−2.42) 90.47(74.41,111.60) 0.56(0.46,0.69) 19.59(14.79,25.93) 0.12(0.09,0.16) −6.08(−6.75,−5.40)
Acute hepatitis B Gabonese Republic 8714.36(6569.46,11030.66) 1714.81(1292.74,2170.62) 4147.32(3122.29,5446.55) 501.46(377.52,658.55) −2.98(−3.28,−2.67) 221.99(97.48,423.99) 43.68(19.18,83.43) 32.22(13.51,60.69) 3.90(1.63,7.34) −6.94(−7.38,−6.49)
Acute hepatitis B Georgia 7414.99(5764.44,9387.06) 412.67(320.81,522.43) 854.54(669.21,1053.64) 91.96(72.01,113.38) −2.99(−3.37,−2.60) 296.74(168.01,427.75) 16.51(9.35,23.81) 13.02(9.44,17.71) 1.40(1.02,1.91) −6.11(−6.92,−5.29)
Acute hepatitis B Grand Duchy of Luxembourg 243.58(185.34,313.71) 276.07(210.06,355.55) 35.31(26.49,46.84) 26.17(19.64,34.72) −3.02(−3.56,−2.49) 0.34(0.25,0.46) 0.39(0.28,0.52) 0.05(0.03,0.07) 0.03(0.02,0.05) −9.40(−10.33,−8.47)
Acute hepatitis B Greenland 85.54(63.11,113.43) 478.10(352.76,634.00) 42.44(31.63,57.97) 276.12(205.76,377.12) −3.15(−3.51,−2.78) 0.56(0.32,0.97) 3.15(1.79,5.42) 0.07(0.04,0.10) 0.45(0.28,0.68) −6.83(−7.53,−6.12)
Acute hepatitis B Grenada 163.50(117.97,223.13) 387.80(279.81,529.26) 12.13(9.13,15.91) 40.28(30.34,52.84) −3.23(−3.93,−2.52) 1.97(1.17,3.54) 4.66(2.79,8.39) 0.58(0.42,0.79) 1.92(1.39,2.61) −2.92(−3.42,−2.41)
Acute hepatitis B Guam 575.48(460.52,737.66) 1062.85(850.54,1362.38) 193.99(155.51,246.80) 400.10(320.74,509.03) −3.28(−3.89,−2.66) 1.48(0.97,2.34) 2.72(1.79,4.32) 0.81(0.55,1.22) 1.68(1.14,2.52) −0.11(−0.93,0.72)
Acute hepatitis B Hashemite Kingdom of Jordan 20,206.68(14960.82,26195.71) 963.77(713.56,1249.42) 4517.97(3390.31,5888.18) 91.73(68.84,119.55) −3.32(−3.88,−2.76) 365.40(194.46,610.59) 17.43(9.27,29.12) 70.78(41.15,116.90) 1.44(0.84,2.37) −8.33(−8.49,−8.16)
Acute hepatitis B Hellenic Republic 13,627.21(10830.01,16687.40) 484.86(385.33,593.74) 712.97(586.04,870.80) 37.42(30.76,45.70) −3.36(−4.14,−2.57) 55.35(46.12,65.96) 1.97(1.64,2.35) 11.04(8.16,14.62) 0.58(0.43,0.77) −5.28(−6.28,−4.26)
Acute hepatitis B Hungary 8840.54(6989.87,11135.75) 304.61(240.85,383.70) 5316.48(4318.20,6592.37) 283.49(230.26,351.52) −3.37(−3.77,−2.97) 38.42(30.78,46.84) 1.32(1.06,1.61) 10.56(7.86,14.17) 0.56(0.42,0.76) −2.61(−3.82,−1.38)
Acute hepatitis B Independent State of Papua New Guinea 47,004.09(32762.27,61974.42) 2208.17(1539.12,2911.45) 54,813.02(41535.34,70103.14) 1118.85(847.82,1430.95) −3.49(−3.68,−3.29) 944.45(370.86,2101.74) 44.37(17.42,98.74) 410.16(166.54,940.43) 8.37(3.40,19.20) −6.04(−6.35,−5.73)
Acute hepatitis B Independent State of Samoa 1261.64(972.37,1597.75) 1377.42(1061.60,1744.37) 641.13(491.49,840.46) 635.14(486.90,832.62) −3.64(−4.30,−2.98) 5.86(3.54,9.17) 6.40(3.86,10.01) 2.93(1.69,4.53) 2.91(1.68,4.49) −2.64(−2.79,−2.49)
Acute hepatitis B Ireland 3113.16(2328.70,4200.89) 234.28(175.25,316.14) 967.27(667.20,1367.08) 73.19(50.48,103.44) −3.67(−4.06,−3.28) 2.84(1.73,4.56) 0.21(0.13,0.34) 0.89(0.53,1.48) 0.07(0.04,0.11) −3.69(−4.30,−3.08)
Acute hepatitis B Islamic Republic of Afghanistan 43,442.65(34188.07,55707.17) 779.53(613.46,999.60) 66,284.07(51671.23,84188.81) 372.87(290.67,473.59) −3.68(−4.53,−2.82) 12,216.27(1732.71,29580.49) 219.21(31.09,530.79) 11,898.20(4806.84,23331.33) 66.93(27.04,131.25) −4.37(−4.94,−3.80)
Acute hepatitis B Islamic Republic of Iran 225,950.31(181240.20,279734.17) 717.09(575.19,887.78) 10,715.31(8667.76,13253.78) 41.44(33.53,51.26) −3.69(−4.44,−2.94) 9246.13(5542.84,14351.17) 29.34(17.59,45.55) 942.76(641.69,1383.69) 3.65(2.48,5.35) −4.92(−5.58,−4.26)
Acute hepatitis B Islamic Republic of Mauritania 34,369.04(26549.36,44484.61) 3030.99(2341.38,3923.08) 24,495.00(18552.07,31379.31) 1050.31(795.48,1345.50) −3.70(−3.88,−3.53) 2904.24(974.91,6278.88) 256.12(85.98,553.73) 487.59(257.11,821.48) 20.91(11.02,35.22) −7.66(−8.18,−7.14)
Acute hepatitis B Islamic Republic of Pakistan 551,006.04(421128.29,706672.61) 903.83(690.79,1159.18) 235,552.27(179836.75,301636.35) 215.66(164.65,276.16) −3.75(−4.34,−3.15) 29,996.63(9488.29,78642.02) 49.20(15.56,129.00) 48,454.81(18939.22,90084.96) 44.36(17.34,82.48) 1.33(0.67,1.99)
Acute hepatitis B Jamaica 3930.94(2805.44,5227.32) 359.81(256.79,478.47) 323.83(236.78,425.97) 39.72(29.04,52.24) −3.76(−4.20,−3.31) 13.36(8.76,21.88) 1.22(0.80,2.00) 8.82(5.77,12.39) 1.08(0.71,1.52) −0.64(−1.09,−0.18)
Acute hepatitis B Japan 228,176.61(187803.99,279863.91) 683.91(562.90,838.83) 74,931.49(57774.70,97718.10) 352.90(272.10,460.21) −3.80(−4.35,−3.26) 327.62(254.85,427.59) 0.98(0.76,1.28) 128.45(99.26,166.45) 0.60(0.47,0.78) −4.60(−7.10,−2.05)
Acute hepatitis B Kingdom of Bahrain 1257.06(1016.05,1571.30) 628.23(507.78,785.27) 272.73(215.07,333.33) 67.59(53.30,82.61) −3.86(−4.31,−3.40) 39.52(24.95,61.66) 19.75(12.47,30.82) 12.79(8.18,18.77) 3.17(2.03,4.65) −5.56(−5.77,−5.36)
Acute hepatitis B Kingdom of Belgium 5221.08(3941.31,6639.90) 211.23(159.46,268.64) 486.68(378.66,644.79) 19.13(14.88,25.34) −3.86(−4.12,−3.60) 27.05(22.90,32.13) 1.09(0.93,1.30) 4.13(3.14,5.39) 0.16(0.12,0.21) −7.41(−8.11,−6.71)
Acute hepatitis B Kingdom of Bhutan 2995.31(2237.99,3906.81) 879.38(657.05,1146.99) 94.66(72.99,119.65) 37.13(28.63,46.93) −3.88(−4.07,−3.70) 108.09(27.24,311.61) 31.73(8.00,91.49) 76.05(28.78,141.23) 29.83(11.29,55.39) −0.51(−1.52,0.52)
Acute hepatitis B Kingdom of Cambodia 106,754.20(77232.91,140251.78) 1875.05(1356.53,2463.40) 17,847.57(12410.23,24087.50) 269.15(187.15,363.25) −3.90(−4.40,−3.40) 2335.04(825.99,5064.09) 41.01(14.51,88.95) 579.87(266.34,987.29) 8.74(4.02,14.89) −5.60(−6.31,−4.88)
Acute hepatitis B Kingdom of Denmark 3174.90(2436.21,4095.31) 253.94(194.85,327.55) 3164.18(2432.44,4156.30) 244.49(187.95,321.15) −4.04(−4.25,−3.82) 9.09(7.31,11.18) 0.73(0.58,0.89) 3.72(2.50,5.35) 0.29(0.19,0.41) −4.40(−4.92,−3.89)
Acute hepatitis B Kingdom of Eswatini 7870.20(5702.44,10542.26) 1649.50(1195.16,2209.53) 1230.62(893.91,1576.61) 230.02(167.08,294.69) −4.06(−4.44,−3.67) 72.82(32.80,133.51) 15.26(6.88,27.98) 22.12(11.95,36.80) 4.14(2.23,6.88) −4.28(−4.76,−3.80)
Acute hepatitis B Kingdom of Lesotho 13,965.77(10488.90,18550.25) 1667.91(1252.67,2215.43) 2410.07(1772.21,3129.36) 287.32(211.27,373.06) −4.06(−4.47,−3.65) 144.45(61.51,265.20) 17.25(7.35,31.67) 60.27(33.06,102.53) 7.18(3.94,12.22) −2.59(−3.05,−2.13)
Acute hepatitis B Kingdom of Morocco 61,904.21(49145.41,78070.46) 496.03(393.80,625.57) 5298.71(4116.72,6524.49) 41.03(31.87,50.52) −4.10(−4.49,−3.70) 1804.26(689.95,3940.90) 14.46(5.53,31.58) 690.74(310.19,1326.55) 5.35(2.40,10.27) −3.08(−3.33,−2.83)
Acute hepatitis B Kingdom of Norway 2517.63(1940.97,3228.04) 226.30(174.46,290.15) 261.08(199.23,351.75) 21.03(16.05,28.33) −4.10(−4.76,−3.44) 2.34(1.48,3.59) 0.21(0.13,0.32) 0.64(0.52,0.78) 0.05(0.04,0.06) −4.56(−5.53,−3.58)
Acute hepatitis B Kingdom of Saudi Arabia 54,236.30(40256.08,70924.13) 660.50(490.25,863.73) 7038.23(5667.54,8700.40) 69.46(55.93,85.86) −4.17(−4.94,−3.38) 4176.24(1835.01,7885.29) 50.86(22.35,96.03) 136.56(61.57,247.97) 1.35(0.61,2.45) −10.61(−11.44,−9.78)
Acute hepatitis B Kingdom of Spain 63,693.25(48970.90,82475.69) 571.39(439.32,739.89) 3930.63(3164.08,5058.83) 44.63(35.93,57.44) −4.17(−4.77,−3.56) 71.62(50.36,101.18) 0.64(0.45,0.91) 4.90(3.41,6.86) 0.06(0.04,0.08) −9.34(−10.24,−8.42)
Acute hepatitis B Kingdom of Sweden 3278.74(2558.94,4220.43) 155.61(121.45,200.30) 2177.74(1563.70,3008.56) 90.16(64.74,124.56) −4.17(−4.46,−3.89) 3.18(2.06,4.69) 0.15(0.10,0.22) 3.39(2.44,4.56) 0.14(0.10,0.19) 0.30(−0.12,0.72)
Acute hepatitis B Kingdom of Thailand 270,853.82(210667.81,340629.32) 1190.73(926.14,1497.48) 20,741.46(16475.68,25674.75) 151.97(120.72,188.12) −4.25(−5.14,−3.36) 1932.43(1295.08,2812.71) 8.50(5.69,12.37) 351.79(261.47,480.56) 2.58(1.92,3.52) −2.82(−3.46,−2.18)
Acute hepatitis B Kingdom of the Netherlands 4428.55(3594.71,5354.54) 115.54(93.78,139.69) 1996.83(1564.07,2613.00) 54.10(42.37,70.79) −4.26(−4.80,−3.72) 8.45(6.57,10.50) 0.22(0.17,0.27) 2.19(1.49,3.17) 0.06(0.04,0.09) −5.49(−6.18,−4.80)
Acute hepatitis B Kingdom of Tonga 660.19(518.51,841.57) 1237.19(971.68,1577.09) 39.86(31.56,48.54) 80.39(63.65,97.90) −4.36(−4.63,−4.09) 103.45(55.76,158.54) 193.86(104.50,297.09) 20.97(9.72,37.57) 42.29(19.61,75.77) −5.07(−5.37,−4.76)
Acute hepatitis B Kyrgyz Republic 11,642.98(8305.91,15152.95) 551.44(393.39,717.68) 2461.30(1953.94,3171.83) 87.19(69.22,112.36) −4.37(−4.92,−3.81) 2583.57(1880.05,3541.55) 122.36(89.04,167.74) 195.10(125.45,288.64) 6.91(4.44,10.23) −8.38(−8.91,−7.85)
Acute hepatitis B Lao People’s Democratic Republic 30,769.14(22563.62,39092.66) 1356.38(994.66,1723.30) 15,810.86(11920.63,20683.61) 528.52(398.48,691.41) −4.55(−5.28,−3.82) 1123.43(202.34,3493.46) 49.52(8.92,154.00) 295.12(152.14,550.44) 9.87(5.09,18.40) −5.95(−6.31,−5.59)
Acute hepatitis B Lebanese Republic 6180.64(5105.79,7517.36) 461.54(381.28,561.36) 2044.09(1723.02,2462.59) 122.68(103.41,147.79) −4.57(−5.34,−3.79) 43.53(22.63,79.82) 3.25(1.69,5.96) 14.38(8.59,23.03) 0.86(0.52,1.38) −4.40(−4.54,−4.27)
Acute hepatitis B Malaysia 46,782.85(38017.29,58088.40) 560.75(455.68,696.26) 6048.87(4930.42,7318.76) 58.98(48.08,71.37) −4.60(−5.19,−4.00) 1632.33(1134.60,2301.02) 19.57(13.60,27.58) 621.57(443.15,862.04) 6.06(4.32,8.41) −3.87(−4.12,−3.61)
Acute hepatitis B Mongolia 17,641.62(14389.23,21262.29) 1554.16(1267.64,1873.13) 3466.35(2882.51,4149.68) 264.06(219.59,316.12) −4.70(−5.13,−4.26) 1403.62(556.27,2925.39) 123.65(49.00,257.72) 119.31(68.06,195.68) 9.09(5.18,14.91) −7.65(−8.33,−6.97)
Acute hepatitis B Montenegro 632.20(471.99,830.88) 294.71(220.02,387.32) 101.40(74.89,132.35) 67.43(49.80,88.01) −4.71(−5.95,−3.45) 1.28(0.71,2.14) 0.60(0.33,1.00) 0.24(0.12,0.47) 0.16(0.08,0.31) −3.62(−4.17,−3.08)
Acute hepatitis B New Zealand 7616.97(5713.12,9989.66) 691.77(518.86,907.25) 2200.71(1693.93,2817.23) 168.83(129.95,216.13) −4.72(−5.67,−3.75) 9.71(6.91,13.70) 0.88(0.63,1.24) 1.95(1.15,2.97) 0.15(0.09,0.23) −6.97(−7.82,−6.10)
Acute hepatitis B North Macedonia 2604.58(2000.09,3438.43) 373.72(286.98,493.36) 347.51(265.97,446.48) 77.82(59.56,99.98) −4.76(−5.47,−4.04) 33.70(14.57,66.16) 4.84(2.09,9.49) 6.37(1.96,15.63) 1.43(0.44,3.50) −3.32(−3.73,−2.92)
Acute hepatitis B Northern Mariana Islands 238.54(193.55,297.70) 1470.96(1193.55,1835.80) 75.86(61.21,93.58) 505.85(408.14,624.02) −4.78(−5.59,−3.97) 0.94(0.64,1.32) 5.77(3.94,8.14) 0.41(0.28,0.61) 2.77(1.85,4.05) −2.87(−3.50,−2.23)
Acute hepatitis B Palestine 8274.90(6543.37,10390.14) 693.29(548.21,870.50) 1742.51(1399.38,2165.78) 72.37(58.12,89.95) −4.80(−5.18,−4.42) 149.86(85.31,249.94) 12.56(7.15,20.94) 38.82(24.52,59.84) 1.61(1.02,2.49) −5.96(−6.23,−5.69)
Acute hepatitis B People’s Democratic Republic of Algeria 77,927.63(62523.60,95662.44) 576.53(462.57,707.74) 12,753.66(10426.42,15387.40) 77.54(63.39,93.55) −4.84(−5.48,−4.19) 4573.73(2217.63,7905.13) 33.84(16.41,58.48) 1053.47(620.78,1622.99) 6.40(3.77,9.87) −4.55(−4.79,−4.32)
Acute hepatitis B People’s Republic of Bangladesh 388,958.19(305169.13,484474.31) 644.40(505.59,802.65) 46,671.30(36660.57,57319.57) 76.52(60.11,93.98) −4.87(−5.49,−4.24) 7298.28(2162.91,19562.53) 12.09(3.58,32.41) 4911.14(1556.15,10904.28) 8.05(2.55,17.88) −0.95(−1.18,−0.72)
Acute hepatitis B People’s Republic of China 8,989,110.27(7089533.19,11411847.19) 2019.84(1593.00,2564.22) 437,749.04(330045.57,576303.62) 130.94(98.73,172.39) −4.92(−5.48,−4.35) 289,221.10(158276.71,441451.88) 64.99(35.56,99.19) 7128.07(4948.27,10091.15) 2.13(1.48,3.02) −11.39(−11.96,−10.81)
Acute hepatitis B Plurinational State of Bolivia 5351.81(4589.09,6341.91) 159.81(137.03,189.38) 1279.32(1061.89,1543.48) 28.14(23.35,33.95) −4.96(−5.68,−4.24) 96.79(33.89,235.38) 2.89(1.01,7.03) 77.69(40.38,141.65) 1.71(0.89,3.12) −1.58(−1.65,−1.51)
Acute hepatitis B Portuguese Republic 9680.10(7298.10,12637.65) 324.73(244.82,423.95) 376.90(285.98,497.25) 19.66(14.92,25.94) −4.97(−5.72,−4.21) 82.83(69.08,97.20) 2.78(2.32,3.26) 9.01(6.58,11.93) 0.47(0.34,0.62) −7.53(−8.36,−6.70)
Acute hepatitis B Principality of Andorra 39.90(29.14,54.37) 296.50(216.52,403.97) 4.31(3.03,5.96) 29.96(21.10,41.46) −5.02(−5.35,−4.69) 1.63(0.79,2.97) 12.13(5.86,22.10) 0.50(0.26,0.89) 3.48(1.83,6.20) −3.73(−4.27,−3.20)
Acute hepatitis B Principality of Monaco 12.72(9.68,16.80) 262.63(199.89,346.83) 0.99(0.78,1.30) 14.66(11.45,19.15) −5.04(−5.82,−4.26) 0.02(0.02,0.03) 0.47(0.32,0.66) 0.01(0.01,0.02) 0.22(0.11,0.36) −4.02(−4.65,−3.40)
Acute hepatitis B Puerto Rico 3395.71(2455.44,4716.14) 254.92(184.33,354.04) 392.83(288.04,521.01) 60.11(44.08,79.73) −5.04(−5.75,−4.33) 5.66(3.72,8.46) 0.42(0.28,0.64) 2.62(1.98,3.39) 0.40(0.30,0.52) 0.01(−1.55,1.58)
Acute hepatitis B Republic of Albania 5167.11(3972.37,6472.57) 357.36(274.73,447.65) 120.23(92.91,151.00) 19.48(15.06,24.47) −5.10(−5.64,−4.56) 96.39(50.21,172.58) 6.67(3.47,11.94) 15.69(5.05,43.78) 2.54(0.82,7.09) −3.36(−3.96,−2.75)
Acute hepatitis B Republic of Angola 150,656.15(101993.21,202416.50) 2612.83(1768.87,3510.51) 259,628.32(187718.33,333951.15) 1390.19(1005.15,1788.16) −5.13(−6.16,−4.09) 27,142.89(4263.60,82979.29) 470.74(73.94,1439.11) 7766.32(2870.24,18594.69) 41.59(15.37,99.57) −7.41(−8.07,−6.75)
Acute hepatitis B Republic of Armenia 6577.07(5197.76,8133.06) 495.33(391.45,612.51) 485.35(374.26,617.71) 63.60(49.04,80.95) −5.14(−5.45,−4.82) 474.77(331.65,673.25) 35.76(24.98,50.70) 11.85(7.42,18.09) 1.55(0.97,2.37) −8.55(−9.14,−7.95)
Acute hepatitis B Republic of Austria 5417.56(4041.24,7223.36) 289.21(215.74,385.62) 863.69(639.38,1133.93) 49.22(36.43,64.62) −5.15(−5.73,−4.56) 9.67(7.49,12.60) 0.52(0.40,0.67) 1.17(0.83,1.66) 0.07(0.05,0.09) −7.60(−8.47,−6.73)
Acute hepatitis B Republic of Azerbaijan 18,149.23(14494.95,22406.08) 579.83(463.08,715.83) 5027.10(3944.07,6247.47) 165.00(129.45,205.05) −5.16(−5.47,−4.85) 2766.27(1741.44,4155.93) 88.38(55.64,132.77) 343.48(177.48,617.80) 11.27(5.83,20.28) −6.22(−6.67,−5.77)
Acute hepatitis B Republic of Belarus 8196.52(5824.71,12002.11) 261.20(185.62,382.47) 313.28(217.94,428.55) 15.47(10.76,21.16) −5.22(−5.73,−4.71) 974.26(744.48,1265.10) 31.05(23.72,40.32) 164.77(103.17,244.79) 8.14(5.09,12.09) −3.35(−3.71,−2.99)
Acute hepatitis B Republic of Benin 44,950.67(33145.89,59376.52) 1566.39(1155.03,2069.08) 27,813.21(20436.88,36938.24) 370.04(271.90,491.44) −5.24(−6.11,−4.37) 2661.70(1478.39,4134.51) 92.75(51.52,144.07) 1114.96(667.98,1769.87) 14.83(8.89,23.55) −5.78(−6.15,−5.40)
Acute hepatitis B Republic of Botswana 11,836.22(8992.31,15491.04) 1598.47(1214.40,2092.05) 2204.01(1707.01,2893.42) 240.35(186.15,315.53) −5.31(−6.01,−4.60) 56.55(29.68,94.42) 7.64(4.01,12.75) 17.23(9.94,26.92) 1.88(1.08,2.94) −4.46(−4.59,−4.34)
Acute hepatitis B Republic of Bulgaria 21,323.01(16998.84,26302.62) 902.26(719.29,1112.97) 1313.00(1053.11,1636.46) 101.45(81.37,126.44) −5.41(−6.18,−4.64) 69.31(49.17,96.12) 2.93(2.08,4.07) 22.91(14.79,33.74) 1.77(1.14,2.61) −2.17(−3.87,−0.44)
Acute hepatitis B Republic of Burundi 26,801.12(19857.74,35169.67) 849.45(629.38,1114.68) 5774.45(4275.18,7754.72) 79.38(58.77,106.60) −5.51(−5.83,−5.19) 781.25(118.98,2086.69) 24.76(3.77,66.14) 874.67(193.67,2085.06) 12.02(2.66,28.66) −1.14(−1.64,−0.64)
Acute hepatitis B Republic of Cabo Verde 3416.11(2436.09,4618.27) 1756.61(1252.68,2374.78) 391.57(270.64,554.05) 203.16(140.42,287.45) −5.56(−6.40,−4.72) 74.62(49.52,108.32) 38.37(25.46,55.70) 8.86(6.15,12.73) 4.60(3.19,6.60) −7.63(−8.06,−7.20)
Acute hepatitis B Republic of Cameroon 94,124.48(72991.99,118572.03) 1585.37(1229.43,1997.15) 67,464.09(51858.52,84193.79) 399.13(306.80,498.11) −5.59(−6.62,−4.54) 698.95(335.97,1639.50) 11.77(5.66,27.61) 572.79(315.42,1069.35) 3.39(1.87,6.33) −2.95(−3.30,−2.60)
Acute hepatitis B Republic of Chad 78,176.98(54028.04,101179.35) 2217.61(1532.59,2870.11) 147,331.25(101592.92,196271.71) 1345.54(927.83,1792.51) −5.60(−6.44,−4.75) 5690.07(2581.81,9342.98) 161.41(73.24,265.03) 7969.53(4831.48,12030.34) 72.78(44.12,109.87) −2.21(−2.59,−1.83)
Acute hepatitis B Republic of Chile 10,664.20(8529.46,13959.51) 202.18(161.71,264.66) 1127.31(868.71,1436.70) 23.04(17.75,29.36) −5.62(−6.54,−4.69) 20.56(15.24,27.37) 0.39(0.29,0.52) 6.44(5.05,8.10) 0.13(0.10,0.17) −4.13(−5.31,−2.94)
Acute hepatitis B Republic of Colombia 187,045.04(129900.81,255411.26) 1242.59(862.97,1696.77) 24,079.65(17413.69,32420.89) 165.39(119.60,222.68) −5.63(−6.50,−4.76) 320.47(226.98,448.17) 2.13(1.51,2.98) 168.07(116.50,245.99) 1.15(0.80,1.69) −1.89(−2.44,−1.34)
Acute hepatitis B Republic of Costa Rica 4776.42(3501.40,6359.72) 336.81(246.90,448.45) 601.42(425.07,837.98) 43.93(31.05,61.21) −5.69(−6.40,−4.98) 13.56(9.26,19.42) 0.96(0.65,1.37) 6.25(4.30,9.10) 0.46(0.31,0.67) −1.95(−2.40,−1.49)
Acute hepatitis B Republic of Croatia 6456.37(5197.29,8251.47) 486.75(391.82,622.08) 342.03(280.35,413.05) 42.45(34.79,51.26) −5.76(−6.74,−4.78) 8.62(6.40,11.73) 0.65(0.48,0.88) 1.13(0.80,1.56) 0.14(0.10,0.19) −5.69(−6.57,−4.81)
Acute hepatitis B Republic of Cuba 7929.41(5458.26,11758.64) 217.12(149.46,321.98) 641.63(448.07,871.76) 26.72(18.66,36.31) −5.78(−6.20,−5.36) 33.55(22.71,48.25) 0.92(0.62,1.32) 7.75(5.83,9.93) 0.32(0.24,0.41) −3.03(−3.39,−2.66)
Acute hepatitis B Republic of Cyprus 969.75(735.45,1244.18) 374.33(283.89,480.26) 102.36(83.14,126.54) 35.91(29.16,44.39) −5.78(−6.25,−5.31) 2.26(1.39,3.79) 0.87(0.54,1.46) 0.37(0.20,0.64) 0.13(0.07,0.22) −6.23(−6.57,−5.89)
Acute hepatitis B Republic of C么te d’Ivoire 116,194.78(86066.44,150140.04) 1679.48(1244.00,2170.12) 68,424.91(49906.80,90138.90) 475.68(346.95,626.63) −5.82(−6.81,−4.83) 4746.68(2702.63,7824.62) 68.61(39.06,113.10) 1135.55(712.18,1790.01) 7.89(4.95,12.44) −6.00(−6.37,−5.64)
Acute hepatitis B Republic of Djibouti 2615.42(1904.73,3492.22) 1166.18(849.29,1557.12) 3338.94(2376.38,4541.30) 631.93(449.76,859.49) −5.84(−6.69,−4.98) 65.66(27.16,140.33) 29.28(12.11,62.57) 80.39(36.45,159.80) 15.21(6.90,30.24) −1.83(−2.23,−1.44)
Acute hepatitis B Republic of Ecuador 9588.00(7685.51,11760.75) 193.40(155.03,237.23) 2471.01(2003.96,2974.44) 37.35(30.29,44.96) −5.86(−6.98,−4.73) 56.80(39.15,84.37) 1.15(0.79,1.70) 35.05(25.23,48.28) 0.53(0.38,0.73) −2.78(−4.11,−1.43)
Acute hepatitis B Republic of El Salvador 11,119.12(7605.61,15142.65) 403.54(276.03,549.56) 1151.08(767.54,1628.01) 48.32(32.22,68.34) −5.90(−7.06,−4.72) 153.22(80.18,256.61) 5.56(2.91,9.31) 40.57(22.64,65.84) 1.70(0.95,2.76) −3.91(−4.22,−3.59)
Acute hepatitis B Republic of Equatorial Guinea 2228.96(1666.92,2863.42) 928.81(694.61,1193.19) 3939.82(3030.97,5115.20) 511.58(393.57,664.20) −5.92(−6.92,−4.91) 7.40(2.72,17.66) 3.08(1.13,7.36) 10.70(5.98,19.75) 1.39(0.78,2.56) −2.64(−2.99,−2.28)
Acute hepatitis B Republic of Estonia 1320.25(968.17,1773.79) 287.44(210.78,386.18) 102.75(73.20,138.53) 36.66(26.12,49.42) −5.92(−7.02,−4.81) 93.00(76.79,112.54) 20.25(16.72,24.50) 3.34(2.49,4.45) 1.19(0.89,1.59) −8.58(−9.45,−7.70)
Acute hepatitis B Republic of Fiji 2361.12(1803.10,3082.23) 658.23(502.67,859.26) 348.41(262.66,472.91) 99.37(74.91,134.87) −6.09(−7.19,−4.97) 53.89(30.93,87.97) 15.02(8.62,24.52) 11.47(6.77,18.06) 3.27(1.93,5.15) −5.11(−5.28,−4.93)
Acute hepatitis B Republic of Finland 3920.04(2941.09,5265.05) 308.96(231.81,414.97) 3262.77(2439.40,4258.50) 284.09(212.40,370.78) −6.09(−6.95,−5.22) 6.00(4.51,8.01) 0.47(0.36,0.63) 3.11(1.98,4.68) 0.27(0.17,0.41) −2.35(−2.52,−2.18)
Acute hepatitis B Republic of Ghana 220,033.58(157523.06,284962.33) 2663.97(1907.15,3450.08) 54,866.50(41739.66,69374.37) 336.31(255.85,425.24) −6.14(−7.21,−5.05) 8402.29(4368.47,14334.92) 101.73(52.89,173.55) 767.59(438.75,1368.97) 4.71(2.69,8.39) −9.16(−9.68,−8.64)
Acute hepatitis B Republic of Guatemala 31,840.90(23360.24,41462.85) 648.39(475.69,844.33) 6904.93(5088.93,9408.29) 104.38(76.93,142.23) −6.22(−7.27,−5.15) 145.67(79.22,249.06) 2.97(1.61,5.07) 128.24(77.18,203.68) 1.94(1.17,3.08) −0.67(−0.98,−0.35)
Acute hepatitis B Republic of Guinea 68,341.02(50469.83,87929.28) 2079.01(1535.35,2674.91) 91,354.02(68353.02,117170.91) 1223.85(915.71,1569.72) −6.27(−7.14,−5.40) 8523.51(3617.10,14949.37) 259.30(110.04,454.78) 3292.27(1983.50,5177.89) 44.11(26.57,69.37) −4.88(−5.31,−4.44)
Acute hepatitis B Republic of Guinea−Bissau 14,687.63(10973.38,19289.76) 2497.49(1865.92,3280.04) 10,457.59(7785.63,14341.35) 934.95(696.06,1282.17) −6.29(−7.22,−5.36) 1009.35(511.98,1774.37) 171.63(87.06,301.71) 281.91(182.65,451.07) 25.20(16.33,40.33) −5.45(−6.03,−4.86)
Acute hepatitis B Republic of Guyana 1926.44(1450.04,2479.41) 504.85(380.00,649.76) 213.59(159.50,287.41) 76.09(56.82,102.39) −6.30(−6.87,−5.72) 4.79(3.20,6.61) 1.26(0.84,1.73) 10.15(6.16,15.47) 3.61(2.19,5.51) 2.05(0.88,3.24)
Acute hepatitis B Republic of Haiti 15,772.62(11968.46,21598.65) 471.33(357.65,645.42) 16,547.74(11669.33,22282.48) 295.09(208.09,397.35) −6.30(−7.21,−5.38) 235.92(37.99,953.26) 7.05(1.14,28.49) 363.27(106.71,1002.93) 6.48(1.90,17.88) −0.38(−0.59,−0.16)
Acute hepatitis B Republic of Honduras 12,106.14(8776.75,16406.34) 446.13(323.44,604.60) 2113.36(1478.94,2956.75) 48.58(33.99,67.96) −6.32(−7.65,−4.97) 269.56(110.01,552.41) 9.93(4.05,20.36) 152.90(59.49,305.75) 3.51(1.37,7.03) −3.53(−3.74,−3.32)
Acute hepatitis B Republic of Iceland 191.30(143.35,256.49) 226.35(169.63,303.50) 183.27(136.66,252.22) 205.67(153.37,283.06) −6.32(−7.20,−5.44) 0.35(0.27,0.46) 0.42(0.32,0.54) 0.17(0.10,0.26) 0.19(0.11,0.29) −3.63(−4.10,−3.17)
Acute hepatitis B Republic of India 3,011,163.27(2253323.95,3900181.25) 733.69(549.03,950.30) 1,600,741.42(1196611.16,2149760.62) 319.78(239.05,429.46) −6.33(−6.72,−5.93) 215,718.09(103001.56,482474.16) 52.56(25.10,117.56) 405,554.71(217956.92,593899.86) 81.02(43.54,118.64) 2.00(1.57,2.43)
Acute hepatitis B Republic of Indonesia 1,031,915.87(817528.63,1301279.02) 1179.83(934.71,1487.80) 376,979.73(299578.85,475978.85) 417.86(332.06,527.59) −6.33(−6.93,−5.73) 10,821.30(4425.11,23519.64) 12.37(5.06,26.89) 6639.62(2964.71,11816.04) 7.36(3.29,13.10) −2.20(−2.49,−1.92)
Acute hepatitis B Republic of Iraq 23,166.90(19494.32,27512.66) 224.95(189.29,267.15) 14,461.74(12235.78,17179.46) 82.00(69.38,97.41) −6.35(−7.51,−5.18) 2064.22(929.08,3696.47) 20.04(9.02,35.89) 1230.85(660.14,2028.18) 6.98(3.74,11.50) −3.18(−3.31,−3.04)
Acute hepatitis B Republic of Italy 101,661.01(77132.94,133727.33) 746.43(566.33,981.87) 5254.14(4112.45,6736.14) 50.14(39.24,64.28) −6.38(−7.51,−5.25) 123.22(90.02,176.02) 0.90(0.66,1.29) 36.27(28.86,44.06) 0.35(0.28,0.42) −3.81(−4.88,−2.74)
Acute hepatitis B Republic of Kazakhstan 20,647.67(16255.50,26097.99) 310.81(244.70,392.86) 2509.40(2005.50,3116.27) 37.32(29.83,46.34) −6.40(−7.18,−5.61) 5961.20(4488.35,7926.36) 89.74(67.56,119.32) 336.97(213.98,524.93) 5.01(3.18,7.81) −9.06(−9.76,−8.35)
Acute hepatitis B Republic of Kenya 212,021.18(167265.36,268765.01) 1537.30(1212.79,1948.73) 61,608.15(47337.63,79562.06) 250.44(192.43,323.42) −6.41(−7.04,−5.78) 4049.10(1941.50,7150.27) 29.36(14.08,51.84) 3869.80(1793.77,7174.51) 15.73(7.29,29.16) −1.64(−2.09,−1.19)
Acute hepatitis B Republic of Kiribati 594.74(451.70,756.82) 1622.61(1232.35,2064.83) 402.33(312.39,522.48) 752.79(584.50,977.61) −6.59(−7.71,−5.45) 53.22(33.09,84.59) 145.20(90.27,230.78) 25.44(13.61,44.66) 47.60(25.47,83.56) −3.87(−4.15,−3.58)
Acute hepatitis B Republic of Korea 167,586.27(131145.00,214608.89) 1052.21(823.41,1347.45) 10,094.88(8395.32,12318.33) 120.42(100.14,146.94) −6.60(−7.06,−6.13) 782.22(491.51,1258.29) 4.91(3.09,7.90) 16.11(10.69,24.09) 0.19(0.13,0.29) −11.93(−12.88,−10.97)
Acute hepatitis B Republic of Latvia 1455.38(1072.74,2061.42) 193.43(142.57,273.97) 76.52(50.65,112.86) 19.77(13.09,29.16) −6.74(−7.69,−5.77) 609.74(507.17,736.28) 81.04(67.41,97.86) 15.49(11.23,21.05) 4.00(2.90,5.44) −8.57(−9.28,−7.87)
Acute hepatitis B Republic of Liberia 30,434.14(22190.55,38241.62) 2227.71(1624.29,2799.19) 31,035.21(22724.78,42484.60) 1112.36(814.50,1522.73) −6.75(−7.24,−6.26) 1353.37(638.71,2141.39) 99.06(46.75,156.74) 528.35(336.88,812.28) 18.94(12.07,29.11) −5.70(−6.09,−5.32)
Acute hepatitis B Republic of Lithuania 2914.58(2126.34,4010.32) 263.13(191.97,362.06) 130.65(95.47,177.44) 24.38(17.82,33.12) −6.76(−7.48,−6.03) 247.54(200.59,302.22) 22.35(18.11,27.29) 8.83(6.77,11.31) 1.65(1.26,2.11) −7.29(−8.19,−6.38)
Acute hepatitis B Republic of Madagascar 134,969.81(98098.42,178695.81) 2006.69(1458.50,2656.80) 106,596.31(77003.32,139408.67) 713.32(515.29,932.89) −6.79(−7.09,−6.48) 2280.11(984.29,3898.42) 33.90(14.63,57.96) 1757.78(747.24,3382.23) 11.76(5.00,22.63) −3.35(−3.55,−3.16)
Acute hepatitis B Republic of Malawi 72,864.35(55042.66,96787.21) 1307.39(987.62,1736.63) 19,139.02(13710.95,25744.26) 180.71(129.46,243.08) −6.81(−7.20,−6.43) 4514.74(1070.48,8622.92) 81.01(19.21,154.72) 3465.30(1976.97,6282.57) 32.72(18.67,59.32) −3.40(−3.94,−2.87)
Acute hepatitis B Republic of Maldives 1059.23(750.73,1458.84) 825.30(584.94,1136.67) 128.55(91.19,173.41) 98.65(69.98,133.08) −6.87(−8.08,−5.64) 18.95(7.03,42.20) 14.76(5.48,32.88) 2.18(1.46,3.15) 1.67(1.12,2.42) −6.87(−7.05,−6.69)
Acute hepatitis B Republic of Mali 70,693.75(54554.30,88884.01) 1429.35(1103.03,1797.14) 74,166.56(54728.71,96355.13) 521.09(384.52,676.98) −7.02(−7.94,−6.08) 485.80(167.59,1453.22) 9.82(3.39,29.38) 684.93(345.60,1556.17) 4.81(2.43,10.93) −1.71(−1.93,−1.49)
Acute hepatitis B Republic of Malta 278.20(207.36,377.55) 241.39(179.92,327.59) 28.67(20.78,40.36) 34.15(24.75,48.07) −7.04(−8.36,−5.69) 0.53(0.40,0.70) 0.46(0.35,0.60) 0.09(0.07,0.12) 0.11(0.09,0.15) −5.98(−6.69,−5.26)
Acute hepatitis B Republic of Mauritius 3716.45(2698.75,4802.63) 862.66(626.43,1114.78) 338.48(251.95,435.72) 114.00(84.86,146.75) −7.16(−8.38,−5.92) 3.41(2.03,5.25) 0.79(0.47,1.22) 0.36(0.24,0.53) 0.12(0.08,0.18) −7.51(−8.55,−6.45)
Acute hepatitis B Republic of Moldova 14,613.04(10686.31,19265.47) 924.13(675.80,1218.35) 705.02(537.88,929.94) 101.26(77.25,133.57) −7.21(−8.43,−5.98) 1548.51(1178.45,1953.08) 97.93(74.53,123.51) 48.11(33.49,67.51) 6.91(4.81,9.70) −7.15(−7.73,−6.57)
Acute hepatitis B Republic of Mozambique 146,838.57(113887.88,186665.86) 1939.56(1504.32,2465.63) 64,208.12(47252.87,81934.02) 361.65(266.15,461.49) −7.26(−8.11,−6.40) 10,242.54(1702.12,23604.01) 135.29(22.48,311.78) 4281.89(2249.19,8002.47) 24.12(12.67,45.07) −6.16(−6.61,−5.72)
Acute hepatitis B Republic of Namibia 12,822.32(10133.61,15759.32) 1683.43(1330.43,2069.02) 5555.23(4081.57,7615.51) 518.51(380.96,710.81) −7.30(−8.72,−5.86) 45.86(24.24,77.28) 6.02(3.18,10.15) 25.64(14.61,42.04) 2.39(1.36,3.92) −2.76(−3.21,−2.31)
Acute hepatitis B Republic of Nauru 51.79(39.12,68.01) 994.06(750.74,1305.31) 7.08(5.19,9.24) 138.06(101.15,180.15) −7.33(−8.52,−6.13) 0.70(0.42,1.12) 13.47(8.11,21.44) 0.20(0.11,0.33) 3.99(2.18,6.49) −4.01(−4.58,−3.44)
Acute hepatitis B Republic of Nicaragua 4647.46(3364.56,6380.70) 206.53(149.52,283.55) 263.50(184.34,353.14) 10.14(7.09,13.59) −7.33(−8.00,−6.67) 147.34(66.26,309.82) 6.55(2.94,13.77) 47.21(21.50,81.89) 1.82(0.83,3.15) −3.49(−3.85,−3.12)
Acute hepatitis B Republic of Niue 9.69(7.19,13.32) 947.87(703.08,1303.13) 0.47(0.37,0.63) 88.94(70.59,119.99) −7.34(−8.14,−6.52) 0.07(0.04,0.12) 6.95(3.94,11.68) 0.03(0.01,0.05) 5.43(2.67,9.69) −3.65(−4.70,−2.59)
Acute hepatitis B Republic of Palau 68.24(51.69,89.79) 1106.86(838.44,1456.44) 10.69(8.11,13.72) 241.33(183.18,309.91) −7.38(−9.15,−5.58) 1.78(1.11,2.80) 28.93(18.08,45.41) 0.37(0.22,0.56) 8.39(4.95,12.67) −3.88(−4.01,−3.76)
Acute hepatitis B Republic of Panama 2720.91(1826.05,3793.80) 250.31(167.98,349.01) 818.09(546.30,1154.52) 54.28(36.25,76.60) −7.51(−8.07,−6.94) 24.33(15.40,36.12) 2.24(1.42,3.32) 23.91(16.27,34.92) 1.59(1.08,2.32) −0.62(−1.13,−0.11)
Acute hepatitis B Republic of Paraguay 8907.11(6765.56,11491.52) 430.48(326.98,555.39) 1988.60(1551.26,2684.97) 74.46(58.08,100.54) −7.65(−8.31,−6.99) 113.07(64.06,191.14) 5.46(3.10,9.24) 56.53(36.43,85.37) 2.12(1.36,3.20) −3.12(−3.65,−2.59)
Acute hepatitis B Republic of Peru 54,309.66(43209.54,67181.70) 509.96(405.73,630.83) 16,750.33(13142.56,21651.11) 133.89(105.05,173.06) −7.67(−8.36,−6.98) 405.38(225.32,710.87) 3.81(2.12,6.68) 112.82(65.77,180.36) 0.90(0.53,1.44) −5.26(−5.79,−4.73)
Acute hepatitis B Republic of Poland 41,116.49(34427.54,49632.32) 330.27(276.54,398.67) 1451.18(1189.64,1798.77) 18.85(15.45,23.36) −7.72(−8.87,−6.56) 57.15(43.60,74.39) 0.46(0.35,0.60) 15.68(12.07,20.24) 0.20(0.16,0.26) −3.16(−6.02,−0.21)
Acute hepatitis B Republic of Rwanda 42,782.86(29609.59,56556.27) 1033.73(715.44,1366.53) 7000.95(5190.72,9387.02) 108.74(80.63,145.80) −7.81(−8.60,−7.01) 2122.08(824.35,4037.23) 51.27(19.92,97.55) 1027.90(452.35,1878.17) 15.97(7.03,29.17) −4.12(−4.66,−3.59)
Acute hepatitis B Republic of San Marino 13.44(10.27,18.04) 224.63(171.62,301.60) 2.02(1.53,2.71) 32.34(24.59,43.40) −7.82(−9.50,−6.12) 0.40(0.23,0.64) 6.65(3.87,10.68) 0.10(0.04,0.18) 1.62(0.71,2.91) −5.04(−5.45,−4.62)
Acute hepatitis B Republic of Senegal 89,982.38(67431.33,119667.58) 2023.47(1516.35,2691.01) 25,770.50(18827.64,33085.73) 317.55(232.00,407.70) −7.84(−8.58,−7.10) 1234.49(739.66,1929.10) 27.76(16.63,43.38) 389.33(213.87,689.14) 4.80(2.64,8.49) −5.34(−5.71,−4.97)
Acute hepatitis B Republic of Serbia 9424.40(7041.39,12243.43) 324.86(242.71,422.03) 992.87(748.88,1291.79) 52.99(39.96,68.94) −7.85(−8.37,−7.32) 209.97(108.86,341.20) 7.24(3.75,11.76) 13.88(7.96,21.61) 0.74(0.42,1.15) −7.70(−8.28,−7.12)
Acute hepatitis B Republic of Seychelles 302.75(224.28,398.33) 969.06(717.89,1275.00) 23.14(18.15,29.33) 75.80(59.44,96.07) −7.89(−8.97,−6.79) 2.64(1.26,5.13) 8.45(4.03,16.43) 0.67(0.33,1.20) 2.18(1.07,3.92) −2.89(−3.32,−2.46)
Acute hepatitis B Republic of Sierra Leone 34,880.09(25844.03,45355.41) 1581.36(1171.69,2056.28) 30,066.95(19447.67,42417.78) 660.72(427.36,932.12) −7.89(−8.54,−7.23) 5598.36(2007.78,10346.22) 253.81(91.03,469.07) 1075.74(638.54,1676.00) 23.64(14.03,36.83) −7.58(−8.24,−6.91)
Acute hepatitis B Republic of Singapore 8195.78(6593.77,10328.61) 889.91(715.96,1121.49) 1014.93(865.17,1193.47) 97.27(82.92,114.38) −7.89(−8.70,−7.07) 7.10(4.47,11.17) 0.77(0.49,1.21) 1.03(0.70,1.44) 0.10(0.07,0.14) −9.14(−10.85,−7.39)
Acute hepatitis B Republic of Slovenia 2553.13(1992.12,3239.51) 458.56(357.80,581.84) 202.51(159.84,254.26) 50.02(39.48,62.81) −7.91(−8.53,−7.28) 9.08(7.15,11.34) 1.63(1.28,2.04) 1.12(0.84,1.44) 0.28(0.21,0.36) −5.39(−6.57,−4.19)
Acute hepatitis B Republic of South Africa 122,122.07(99492.33,151507.87) 693.02(564.60,859.78) 28,989.64(22842.55,36807.31) 145.54(114.68,184.79) −7.98(−9.01,−6.93) 736.51(519.15,986.19) 4.18(2.95,5.60) 311.87(219.59,423.22) 1.57(1.10,2.12) −3.17(−3.47,−2.87)
Acute hepatitis B Republic of South Sudan 44,209.80(33083.81,58735.46) 1345.37(1006.79,1787.41) 54,138.94(39565.81,73034.54) 986.61(721.04,1330.96) −8.01(−9.54,−6.46) 1432.67(395.95,3117.76) 43.60(12.05,94.88) 2144.42(886.19,3898.63) 39.08(16.15,71.05) 0.30(−0.01,0.61)
Acute hepatitis B Republic of Sudan 174,981.35(133556.98,226282.11) 1584.10(1209.08,2048.52) 102,097.80(76266.74,130405.09) 477.65(356.80,610.08) −8.06(−9.24,−6.86) 18,326.97(3063.46,39890.82) 165.91(27.73,361.13) 5582.99(2777.88,10532.13) 26.12(13.00,49.27) −5.74(−6.12,−5.36)
Acute hepatitis B Republic of Suriname 587.18(429.09,794.09) 343.40(250.95,464.40) 131.07(94.62,177.86) 69.04(49.84,93.68) −8.07(−8.90,−7.23) 15.08(8.95,23.93) 8.82(5.23,13.99) 7.00(4.38,11.42) 3.69(2.31,6.01) −3.14(−3.41,−2.88)
Acute hepatitis B Republic of Tajikistan 14,694.93(11654.98,18589.32) 511.22(405.46,646.70) 3613.19(2677.42,4680.27) 81.10(60.10,105.05) −8.18(−8.52,−7.84) 10,878.26(7169.86,15406.56) 378.44(249.43,535.98) 4050.25(1694.38,9040.73) 90.91(38.03,202.93) −4.25(−4.74,−3.76)
Acute hepatitis B Republic of the Congo 25,997.52(19008.66,34555.61) 1959.59(1432.79,2604.66) 20,618.08(14440.80,27170.22) 829.09(580.69,1092.56) −8.23(−9.06,−7.39) 3118.48(570.93,9621.03) 235.06(43.03,725.19) 514.07(148.60,1156.57) 20.67(5.98,46.51) −7.64(−8.36,−6.91)
Acute hepatitis B Republic of the Gambia 6898.82(5417.78,8575.21) 1228.00(964.38,1526.40) 2594.17(2130.28,3108.42) 204.81(168.19,245.41) −8.29(−9.12,−7.46) 57.49(30.19,112.36) 10.23(5.37,20.00) 24.29(10.77,54.26) 1.92(0.85,4.28) −5.33(−5.78,−4.87)
Acute hepatitis B Republic of the Marshall Islands 387.73(297.98,497.71) 1447.71(1112.60,1858.38) 80.21(58.07,108.62) 347.64(251.68,470.79) −8.31(−9.09,−7.53) 1.90(0.95,3.25) 7.10(3.55,12.13) 0.69(0.33,1.18) 2.98(1.43,5.10) −3.21(−3.68,−2.74)
Acute hepatitis B Republic of the Niger 117,485.08(92012.61,146209.11) 2421.58(1896.54,3013.63) 180,697.21(130708.16,236254.62) 1159.30(838.58,1515.74) −8.38(−9.30,−7.44) 11,131.27(3634.21,20082.75) 229.44(74.91,413.94) 4625.26(2726.22,8363.77) 29.67(17.49,53.66) −6.06(−6.36,−5.75)
Acute hepatitis B Republic of the Philippines 763,932.17(588679.46,972240.65) 2383.37(1836.60,3033.27) 311,763.84(246014.47,395349.72) 696.25(549.41,882.92) −8.40(−9.42,−7.37) 18,979.50(11125.40,30207.77) 59.21(34.71,94.24) 1410.89(1091.77,1790.93) 3.15(2.44,4.00) −10.00(−10.75,−9.25)
Acute hepatitis B Republic of the Union of Myanmar 102,945.10(80254.18,132096.49) 538.66(419.93,691.20) 43,364.15(32094.49,55721.63) 208.80(154.54,268.30) −8.42(−9.32,−7.51) 815.70(128.67,2897.26) 4.27(0.67,15.16) 662.37(154.15,1485.43) 3.19(0.74,7.15) −1.31(−1.48,−1.13)
Acute hepatitis B Republic of Trinidad and Tobago 1666.93(1220.21,2262.47) 320.89(234.89,435.53) 318.22(230.00,429.44) 87.43(63.19,117.98) −8.44(−9.46,−7.41) 15.13(10.45,21.61) 2.91(2.01,4.16) 7.00(4.95,9.65) 1.92(1.36,2.65) −0.98(−1.57,−0.38)
Acute hepatitis B Republic of Tunisia 32,134.04(23973.60,40734.13) 805.35(600.83,1020.89) 2056.89(1612.55,2576.05) 57.37(44.97,71.85) −8.46(−9.41,−7.50) 1538.53(679.48,3056.28) 38.56(17.03,76.60) 127.10(61.17,239.52) 3.54(1.71,6.68) −7.00(−7.50,−6.49)
Acute hepatitis B Republic of Turkey 181,020.87(139851.17,229271.06) 678.45(524.15,859.28) 24,018.76(19084.09,29331.55) 97.19(77.23,118.69) −8.47(−8.96,−7.98) 14,246.42(6418.55,27520.87) 53.39(24.06,103.15) 559.04(364.36,845.03) 2.26(1.47,3.42) −11.21(−12.00,−10.42)
Acute hepatitis B Republic of Uganda 169,480.54(127013.31,220503.11) 1645.80(1233.40,2141.27) 84,898.76(66017.05,104464.84) 340.36(264.67,418.81) −8.48(−9.52,−7.42) 8981.42(3109.15,18460.74) 87.22(30.19,179.27) 5688.50(2883.17,10904.91) 22.81(11.56,43.72) −4.75(−5.15,−4.34)
Acute hepatitis B Republic of Uzbekistan 129,939.21(102098.08,165592.27) 1217.14(956.35,1551.10) 17,492.96(13927.06,21528.31) 138.72(110.44,170.72) −8.56(−9.63,−7.48) 32,419.09(22625.62,43200.78) 303.67(211.93,404.66) 1501.27(1092.57,2120.46) 11.91(8.66,16.82) −9.91(−10.32,−9.50)
Acute hepatitis B Republic of Vanuatu 1369.66(1061.61,1750.97) 1641.34(1272.18,2098.27) 868.29(665.58,1139.96) 588.92(451.43,773.18) −8.59(−9.68,−7.48) 17.35(7.41,35.50) 20.79(8.88,42.54) 6.12(2.54,12.33) 4.15(1.72,8.36) −5.35(−5.59,−5.11)
Acute hepatitis B Republic of Yemen 134,880.46(102266.05,170151.46) 1604.17(1216.28,2023.66) 84,626.98(64054.85,104459.68) 484.35(366.61,597.87) −8.61(−9.51,−7.71) 19,925.79(2000.57,58758.12) 236.98(23.79,698.83) 4756.13(2354.94,8372.29) 27.22(13.48,47.92) −7.36(−7.64,−7.08)
Acute hepatitis B Republic of Zambia 57,827.48(43116.88,73966.22) 1230.24(917.28,1573.58) 18,863.38(14340.09,24467.66) 180.44(137.17,234.05) −8.62(−9.68,−7.55) 5440.70(1499.31,10446.20) 115.75(31.90,222.24) 2109.52(1129.82,3811.75) 20.18(10.81,36.46) −5.73(−6.31,−5.15)
Acute hepatitis B Republic of Zimbabwe 215,642.59(171893.57,261760.59) 3580.70(2854.25,4346.48) 61,836.53(47263.46,78678.64) 774.48(591.96,985.42) −8.76(−9.57,−7.94) 605.55(280.48,1129.57) 10.06(4.66,18.76) 211.55(102.27,410.62) 2.65(1.28,5.14) −3.89(−4.64,−3.14)
Acute hepatitis B Romania 75,475.22(58642.47,92035.92) 1005.95(781.60,1226.68) 3780.53(3003.11,4661.86) 93.56(74.32,115.37) −8.77(−9.64,−7.90) 376.39(246.86,590.30) 5.02(3.29,7.87) 34.80(23.11,49.89) 0.86(0.57,1.23) −6.27(−6.93,−5.61)
Acute hepatitis B Russian Federation 163,033.43(120852.47,219602.55) 360.81(267.46,486.01) 8449.37(6404.13,11086.58) 25.01(18.95,32.81) −8.88(−10.08,−7.65) 6788.71(6105.07,7417.41) 15.02(13.51,16.42) 799.05(674.94,896.60) 2.36(2.00,2.65) −5.74(−6.53,−4.94)
Acute hepatitis B Saint Kitts and Nevis 71.11(53.55,95.06) 387.10(291.50,517.42) 3.93(2.89,5.23) 27.92(20.54,37.21) −9.01(−9.81,−8.20) 0.91(0.59,1.36) 4.94(3.22,7.40) 0.27(0.19,0.36) 1.90(1.34,2.54) −3.98(−4.50,−3.46)
Acute hepatitis B Saint Lucia 242.78(178.32,332.05) 363.58(267.03,497.25) 19.74(13.90,25.92) 47.04(33.13,61.77) −9.01(−10.27,−7.74) 2.34(1.64,3.40) 3.50(2.45,5.10) 0.41(0.30,0.57) 0.97(0.71,1.36) −4.51(−5.32,−3.70)
Acute hepatitis B Saint Vincent and the Grenadines 193.71(145.51,261.66) 360.38(270.70,486.78) 8.74(6.21,11.78) 25.94(18.41,34.96) −9.04(−10.10,−7.97) 0.30(0.22,0.41) 0.56(0.42,0.77) 0.27(0.20,0.36) 0.81(0.60,1.08) 0.05(−1.69,1.82)
Acute hepatitis B Slovak Republic 8032.98(6259.97,10073.87) 457.67(356.65,573.94) 274.66(210.64,352.31) 24.50(18.79,31.43) −9.08(−9.60,−8.56) 25.95(16.51,38.34) 1.48(0.94,2.18) 12.72(5.14,24.80) 1.13(0.46,2.21) −0.56(−1.13,0.02)
Acute hepatitis B Socialist Republic of Viet Nam 740,387.82(575318.09,936112.26) 2199.16(1708.85,2780.51) 117,193.21(91409.33,147644.19) 370.64(289.10,466.95) −9.18(−10.14,−8.22) 4035.71(2492.08,6202.40) 11.99(7.40,18.42) 413.56(246.67,639.21) 1.31(0.78,2.02) −6.97(−7.21,−6.72)
Acute hepatitis B Solomon Islands 4077.84(3142.33,5205.58) 2095.32(1614.62,2674.78) 1461.13(1079.81,1870.24) 441.77(326.48,565.47) −9.27(−9.98,−8.54) 123.55(43.67,279.07) 63.48(22.44,143.39) 29.17(10.95,68.95) 8.82(3.31,20.85) −6.40(−6.51,−6.29)
Acute hepatitis B State of Eritrea 30,752.06(23097.59,41274.69) 1563.57(1174.38,2098.58) 4350.86(3190.00,6071.53) 135.26(99.17,188.75) −9.31(−10.09,−8.53) 798.37(287.89,1584.43) 40.59(14.64,80.56) 646.87(250.31,1285.53) 20.11(7.78,39.96) −2.22(−2.55,−1.89)
Acute hepatitis B State of Israel 3390.75(2668.49,4331.58) 169.00(133.00,215.90) 437.28(346.09,551.78) 12.96(10.26,16.36) −9.36(−10.58,−8.12) 48.80(35.96,68.01) 2.43(1.79,3.39) 6.51(4.60,9.03) 0.19(0.14,0.27) −8.35(−8.91,−7.79)
Acute hepatitis B State of Kuwait 1430.27(1142.45,1820.32) 208.51(166.55,265.37) 210.26(167.96,263.62) 19.19(15.33,24.06) −9.41(−10.51,−8.28) 5.32(4.23,6.61) 0.78(0.62,0.96) 1.67(1.20,2.18) 0.15(0.11,0.20) −5.80(−6.23,−5.36)
Acute hepatitis B State of Libya 12,939.30(10027.71,16059.21) 560.56(434.42,695.72) 2253.27(1788.60,2803.03) 107.94(85.68,134.27) −9.46(−10.55,−8.35) 374.88(152.37,773.05) 16.24(6.60,33.49) 114.78(69.29,186.33) 5.50(3.32,8.93) −3.25(−3.65,−2.85)
Acute hepatitis B State of Qatar 686.01(573.17,827.63) 448.14(374.42,540.66) 282.66(242.26,333.66) 47.34(40.57,55.88) −9.48(−10.05,−8.90) 13.87(9.04,20.91) 9.06(5.90,13.66) 8.27(4.37,12.65) 1.38(0.73,2.12) −5.70(−5.96,−5.45)
Acute hepatitis B Sultanate of Oman 7281.12(5577.62,9644.89) 726.44(556.48,962.28) 721.68(555.37,943.54) 48.38(37.23,63.25) −9.65(−11.01,−8.28) 22.54(9.79,48.52) 2.25(0.98,4.84) 8.71(4.51,15.06) 0.58(0.30,1.01) −3.29(−3.98,−2.60)
Acute hepatitis B Swiss Confederation 3901.85(2981.70,4987.04) 247.40(189.05,316.20) 3031.79(2313.87,4087.98) 172.01(131.28,231.93) −9.72(−10.66,−8.76) 23.16(18.47,29.22) 1.47(1.17,1.85) 4.93(3.46,6.68) 0.28(0.20,0.38) −6.79(−7.36,−6.20)
Acute hepatitis B Syrian Arab Republic 67,639.31(53306.33,84099.71) 920.02(725.07,1143.91) 14,305.42(11627.49,17757.80) 262.96(213.74,326.42) −9.78(−11.02,−8.54) 448.22(196.09,892.90) 6.10(2.67,12.15) 40.47(25.43,61.30) 0.74(0.47,1.13) −7.01(−7.57,−6.46)
Acute hepatitis B Taiwan (Province of China) 191,068.85(149512.31,235432.29) 2614.18(2045.61,3221.15) 7430.96(6093.81,8869.52) 183.69(150.63,219.25) −9.79(−10.74,−8.82) 172.32(102.89,270.94) 2.36(1.41,3.71) 8.21(5.59,11.67) 0.20(0.14,0.29) −8.87(−9.87,−7.86)
Acute hepatitis B Togolese Republic 43,902.91(34225.93,56448.15) 2039.41(1589.89,2622.17) 33,517.34(24831.71,45191.56) 802.73(594.71,1082.33) −9.80(−10.58,−9.02) 201.40(101.03,423.24) 9.36(4.69,19.66) 143.97(76.07,243.58) 3.45(1.82,5.83) −2.55(−3.02,−2.08)
Acute hepatitis B Tokelau 10.31(7.87,13.46) 1359.52(1037.12,1774.53) 0.65(0.50,0.84) 127.76(97.35,165.15) −9.81(−11.09,−8.51) 0.09(0.04,0.16) 12.17(5.69,21.69) 0.12(0.06,0.20) 22.76(11.02,38.82) −2.33(−3.87,−0.77)
Acute hepatitis B Turkmenistan 9577.80(7226.38,12194.49) 508.04(383.31,646.84) 616.09(472.10,796.16) 31.42(24.08,40.61) −9.81(−11.07,−8.54) 6793.60(4897.64,9313.57) 360.36(259.79,494.03) 675.18(415.56,1041.56) 34.44(21.20,53.13) −7.14(−7.64,−6.63)
Acute hepatitis B Tuvalu 69.96(52.77,90.12) 1637.33(1234.93,2109.06) 18.93(14.77,23.99) 385.35(300.63,488.25) −9.92(−10.94,−8.89) 0.64(0.32,1.20) 15.04(7.57,28.05) 0.17(0.10,0.27) 3.53(2.01,5.52) −4.79(−4.99,−4.59)
Acute hepatitis B Ukraine 34,770.33(24923.35,46835.10) 231.01(165.59,311.16) 11,339.68(8065.87,15806.33) 134.27(95.51,187.16) −10.00(−11.14,−8.85) 3942.21(3123.41,4911.34) 26.19(20.75,32.63) 259.40(190.75,342.48) 3.07(2.26,4.06) −5.63(−6.80,−4.45)
Acute hepatitis B Union of the Comoros 3448.23(2366.21,4729.12) 1304.58(895.21,1789.18) 858.47(562.55,1232.35) 273.44(179.19,392.53) −10.16(−11.30,−9.01) 68.08(30.67,123.37) 25.76(11.61,46.67) 44.99(19.86,83.65) 14.33(6.32,26.65) −2.27(−2.61,−1.93)
Acute hepatitis B United Arab Emirates 1424.38(1141.11,1787.45) 201.46(161.40,252.82) 594.85(464.89,735.24) 35.09(27.43,43.37) −10.61(−11.95,−9.25) 46.88(26.16,84.64) 6.63(3.70,11.97) 30.04(18.31,43.48) 1.77(1.08,2.56) −2.74(−3.21,−2.27)
Acute hepatitis B United Kingdom of Great Britain and Northern Ireland 40,109.64(31300.39,50807.18) 270.39(211.01,342.51) 31,387.75(23498.29,41745.10) 200.50(150.10,266.66) −10.64(−12.25,−9.00) 40.66(27.03,59.72) 0.27(0.18,0.40) 46.16(34.91,61.32) 0.29(0.22,0.39) 0.87(−0.73,2.50)
Acute hepatitis B United Mexican States 95,824.95(73595.19,121439.02) 220.96(169.70,280.03) 16,953.10(12438.21,22871.89) 39.29(28.82,53.00) −10.78(−11.80,−9.74) 1873.67(1623.33,2168.26) 4.32(3.74,5.00) 1592.23(1126.36,2204.85) 3.69(2.61,5.11) 0.25(−0.68,1.19)
Acute hepatitis B United Republic of Tanzania 188,040.17(147378.80,237522.63) 1260.05(987.58,1591.63) 43,236.94(33547.90,55535.53) 140.11(108.72,179.97) −10.82(−12.26,−9.36) 9100.50(3865.33,16557.54) 60.98(25.90,110.95) 5065.44(2409.93,9890.56) 16.42(7.81,32.05) −3.99(−4.35,−3.62)
Acute hepatitis B United States of America 95,751.72(75150.66,122707.99) 129.31(101.49,165.72) 13,429.18(10814.94,17043.05) 16.52(13.30,20.96) −10.86(−11.93,−9.77) 763.97(695.51,834.55) 1.03(0.94,1.13) 168.44(140.95,197.11) 0.21(0.17,0.24) −6.20(−6.93,−5.46)
Acute hepatitis B United States Virgin Islands 100.79(73.35,137.58) 241.61(175.85,329.81) 15.78(11.61,21.24) 86.61(63.71,116.58) −11.54(−12.86,−10.20) 0.26(0.17,0.42) 0.63(0.41,1.01) 0.07(0.03,0.15) 0.40(0.16,0.83) −1.07(−1.57,−0.56)
Acute hepatitis E American Samoa 94.93(72.25,127.69) 396.76(301.98,533.69) 70.38(52.55,92.43) 367.95(274.71,483.20) −0.25(−0.27,−0.23) 0.26(0.16,0.39) 1.10(0.66,1.62) 0.16(0.10,0.27) 0.85(0.52,1.42) −1.08(−1.27,−0.90)
Acute hepatitis E Antigua and Barbuda 95.32(70.06,127.77) 399.00(293.26,534.83) 88.26(66.89,116.17) 377.76(286.30,497.24) −0.20(−0.21,−0.18) 0.14(0.07,0.23) 0.57(0.29,0.95) 0.13(0.07,0.22) 0.55(0.29,0.93) 0.09(−0.08,0.26)
Acute hepatitis E Arab Republic of Egypt 54,836.83(40971.92,72348.96) 196.39(146.73,259.10) 85,979.85(65498.10,112311.75) 184.70(140.70,241.27) −0.16(−0.19,−0.13) 2592.05(711.37,6497.68) 9.28(2.55,23.27) 916.97(306.21,2022.81) 1.97(0.66,4.35) −4.24(−4.88,−3.60)
Acute hepatitis E Argentine Republic 6512.85(5040.15,8493.20) 50.00(38.69,65.20) 6775.90(5122.93,8841.66) 49.42(37.36,64.48) 0.12(0.05,0.20) 20.19(12.08,35.23) 0.16(0.09,0.27) 11.43(7.69,16.74) 0.08(0.06,0.12) −1.56(−2.00,−1.11)
Acute hepatitis E Australia 7013.91(5376.80,8954.04) 135.61(103.96,173.12) 8606.26(6626.13,11041.86) 137.96(106.22,177.00) 0.04(0.02,0.06) 10.50(7.07,15.33) 0.20(0.14,0.30) 12.75(8.30,19.36) 0.20(0.13,0.31) 0.13(−0.15,0.41)
Acute hepatitis E Barbados 323.61(242.71,434.58) 381.15(285.87,511.85) 245.00(182.78,327.28) 369.08(275.36,493.03) −0.11(−0.12,−0.09) 0.53(0.29,0.87) 0.62(0.35,1.02) 0.45(0.25,0.74) 0.67(0.37,1.12) 0.35(0.06,0.64)
Acute hepatitis E Belize 419.73(320.52,563.88) 409.19(312.47,549.72) 664.44(499.48,881.79) 393.04(295.47,521.61) −0.12(−0.14,−0.10) 0.66(0.37,1.04) 0.64(0.36,1.02) 1.00(0.50,1.77) 0.59(0.30,1.05) −0.19(−0.31,−0.06)
Acute hepatitis E Bermuda 60.47(45.75,80.55) 380.28(287.71,506.60) 43.10(32.12,57.66) 374.87(279.41,501.49) −0.04(−0.06,−0.03) 0.08(0.04,0.13) 0.48(0.23,0.83) 0.06(0.03,0.11) 0.51(0.25,0.94) 0.17(0.08,0.26)
Acute hepatitis E Bolivarian Republic of Venezuela 13,096.28(10427.23,16285.59) 144.29(114.89,179.43) 13,868.36(10436.44,18364.55) 158.46(119.25,209.84) 0.39(0.23,0.55) 31.91(21.21,49.55) 0.35(0.23,0.55) 32.30(18.23,53.56) 0.37(0.21,0.61) −0.14(−0.71,0.43)
Acute hepatitis E Bosnia and Herzegovina 6420.99(4816.26,8600.75) 433.34(325.04,580.44) 2714.49(2061.31,3533.39) 408.15(309.94,531.27) −0.34(−0.42,−0.26) 7.43(3.64,13.45) 0.50(0.25,0.91) 3.11(1.48,5.70) 0.47(0.22,0.86) −0.34(−0.40,−0.29)
Acute hepatitis E Brunei Darussalam 316.18(241.54,404.01) 274.88(209.99,351.24) 337.33(264.55,435.81) 261.22(204.86,337.47) −0.19(−0.21,−0.17) 7.22(2.80,14.77) 6.28(2.44,12.84) 2.32(0.83,4.49) 1.80(0.64,3.48) −5.01(−5.56,−4.45)
Acute hepatitis E Burkina Faso 22,640.85(17348.04,29687.34) 400.21(306.65,524.77) 50,724.74(37651.21,65315.12) 396.11(294.02,510.04) −0.06(−0.08,−0.04) 472.36(108.32,1107.74) 8.35(1.91,19.58) 401.81(111.71,1332.18) 3.14(0.87,10.40) −2.80(−3.19,−2.40)
Acute hepatitis E Canada 10,505.87(7923.95,13465.06) 137.07(103.38,175.68) 11,312.16(8490.27,14912.75) 137.47(103.18,181.22) −0.02(−0.06,0.02) 11.83(7.07,18.64) 0.15(0.09,0.24) 13.27(7.95,21.72) 0.16(0.10,0.26) 0.07(0.00,0.13)
Acute hepatitis E Central African Republic 9023.80(6966.77,11609.84) 602.73(465.34,775.47) 17,503.70(13721.47,22414.76) 604.83(474.13,774.52) −0.02(−0.03,−0.01) 189.89(26.01,563.01) 12.68(1.74,37.61) 144.39(33.83,412.56) 4.99(1.17,14.26) −2.96(−3.03,−2.88)
Acute hepatitis E Commonwealth of Dominica 133.16(101.42,176.42) 406.32(309.45,538.32) 74.51(55.92,98.94) 383.58(287.85,509.31) −0.20(−0.21,−0.18) 0.23(0.12,0.37) 0.69(0.38,1.12) 0.15(0.08,0.23) 0.76(0.42,1.20) 0.40(0.26,0.55)
Acute hepatitis E Commonwealth of the Bahamas 416.14(314.98,542.95) 386.53(292.57,504.32) 433.69(322.86,588.39) 376.25(280.10,510.46) −0.09(−0.11,−0.07) 0.56(0.29,1.00) 0.52(0.27,0.93) 0.63(0.30,1.12) 0.54(0.26,0.98) 0.15(0.09,0.21)
Acute hepatitis E Cook Islands 32.94(24.46,43.57) 382.61(284.13,506.02) 18.70(14.20,24.66) 360.89(273.94,475.89) −0.21(−0.23,−0.19) 0.04(0.02,0.07) 0.45(0.24,0.77) 0.02(0.01,0.04) 0.43(0.22,0.73) −0.11(−0.17,−0.06)
Acute hepatitis E Czech Republic 12,160.94(9279.30,16122.20) 399.52(304.85,529.66) 9061.81(6898.14,12002.31) 408.09(310.65,540.52) 0.10(0.04,0.16) 21.37(13.26,35.96) 0.70(0.44,1.18) 12.34(7.22,21.40) 0.56(0.32,0.96) −0.50(−0.71,−0.29)
Acute hepatitis E Democratic People’s Republic of Korea 40,407.06(30288.21,52748.92) 518.75(388.84,677.19) 32,584.99(24347.55,43153.63) 493.54(368.77,653.62) −0.25(−0.29,−0.21) 169.53(44.16,416.90) 2.18(0.57,5.35) 46.28(22.55,79.90) 0.70(0.34,1.21) −3.86(−4.19,−3.53)
Acute hepatitis E Democratic Republic of Sao Tome and Principe 241.80(184.79,313.83) 346.00(264.42,449.07) 337.09(252.51,447.15) 331.12(248.04,439.23) −0.16(−0.19,−0.13) 1.49(0.60,3.00) 2.14(0.86,4.30) 0.55(0.33,0.89) 0.54(0.32,0.87) −4.76(−5.08,−4.44)
Acute hepatitis E Democratic Republic of the Congo 119,600.33(93600.01,154963.46) 552.42(432.33,715.76) 261,661.78(200579.28,338070.92) 546.19(418.68,705.68) −0.03(−0.06,−0.01) 460.53(139.61,1183.63) 2.13(0.64,5.47) 576.27(248.80,1050.92) 1.20(0.52,2.19) −1.57(−1.88,−1.26)
Acute hepatitis E Democratic Republic of Timor−Leste 1396.78(1051.77,1806.52) 343.47(258.63,444.23) 2241.78(1697.50,2898.91) 327.06(247.65,422.93) −0.20(−0.21,−0.18) 5.44(2.01,12.74) 1.34(0.50,3.13) 4.92(2.49,8.59) 0.72(0.36,1.25) −2.77(−3.11,−2.42)
Acute hepatitis E Democratic Socialist Republic of Sri Lanka 23,788.08(17807.51,31631.63) 328.56(245.96,436.89) 21,528.14(16229.10,28329.17) 312.01(235.21,410.57) −0.14(−0.16,−0.11) 95.02(51.05,158.90) 1.31(0.71,2.19) 38.32(24.16,56.30) 0.56(0.35,0.82) −3.63(−3.98,−3.28)
Acute hepatitis E Dominican Republic 14,213.20(10849.59,18753.26) 405.84(309.80,535.48) 15,331.04(11642.22,20180.80) 394.04(299.23,518.70) −0.13(−0.15,−0.11) 41.96(20.38,69.83) 1.20(0.58,1.99) 38.19(20.53,60.67) 0.98(0.53,1.56) −0.57(−0.76,−0.37)
Acute hepatitis E Eastern Republic of Uruguay 1227.25(939.15,1601.30) 113.95(87.20,148.68) 965.52(746.74,1263.14) 106.88(82.67,139.83) −0.07(−0.12,−0.02) 1.34(0.78,2.19) 0.12(0.07,0.20) 1.07(0.62,1.79) 0.12(0.07,0.20) −0.05(−0.14,0.05)
Acute hepatitis E Federal Democratic Republic of Ethiopia 196,137.31(151907.31,248126.81) 665.61(515.51,842.04) 363,804.95(283085.59,463300.04) 636.04(494.92,809.99) −0.10(−0.13,−0.08) 3089.85(675.62,11312.83) 10.49(2.29,38.39) 4425.24(1388.93,10259.98) 7.74(2.43,17.94) −1.32(−1.67,−0.96)
Acute hepatitis E Federal Democratic Republic of Nepal 52,987.60(41070.64,68440.16) 512.02(396.86,661.33) 62,549.18(47671.70,82474.46) 502.22(382.77,662.20) −0.08(−0.12,−0.04) 824.84(171.98,3216.20) 7.97(1.66,31.08) 886.56(347.18,1966.22) 7.12(2.79,15.79) −0.01(−0.19,0.16)
Acute hepatitis E Federal Republic of Germany 17,805.18(13514.47,22822.30) 102.74(77.98,131.69) 16,136.84(12240.12,20893.39) 101.19(76.76,131.02) −0.05(−0.11,0.01) 23.06(14.89,34.68) 0.13(0.09,0.20) 45.16(34.00,58.40) 0.28(0.21,0.37) 2.71(2.35,3.07)
Acute hepatitis E Federal Republic of Nigeria 216,609.54(167854.76,279705.35) 446.44(345.96,576.49) 571,767.03(438859.63,742543.30) 447.49(343.47,581.15) 0.07(0.04,0.10) 15,257.61(1775.34,48119.16) 31.45(3.66,99.18) 4598.77(1338.59,10517.39) 3.60(1.05,8.23) −7.56(−8.24,−6.88)
Acute hepatitis E Federal Republic of Somalia 27,022.99(20839.64,34530.30) 571.03(440.37,729.67) 71,685.45(53743.42,92526.82) 560.73(420.38,723.75) −0.02(−0.05,0.01) 857.50(79.78,3429.53) 18.12(1.69,72.47) 1731.63(242.05,6561.41) 13.54(1.89,51.32) −0.93(−1.13,−0.73)
Acute hepatitis E Federated States of Micronesia 242.42(180.73,319.33) 421.61(314.32,555.38) 158.71(119.57,204.76) 382.95(288.52,494.07) −0.27(−0.30,−0.24) 1.07(0.58,2.16) 1.86(1.01,3.76) 0.36(0.21,0.60) 0.86(0.51,1.44) −2.67(−2.79,−2.55)
Acute hepatitis E Federative Republic of Brazil 100,141.50(75436.49,128058.93) 149.04(112.27,190.58) 95,890.85(73103.98,123594.78) 150.02(114.37,193.37) 0.04(0.01,0.06) 587.45(499.53,707.59) 0.87(0.74,1.05) 195.39(140.07,262.77) 0.31(0.22,0.41) −2.57(−3.12,−2.01)
Acute hepatitis E French Republic 13,277.06(10445.86,16878.05) 82.25(64.71,104.56) 12,711.03(9823.17,16528.69) 80.70(62.36,104.93) −0.02(−0.18,0.14) 16.93(10.84,25.53) 0.10(0.07,0.16) 20.79(14.27,30.21) 0.13(0.09,0.19) 1.27(0.99,1.55)
Acute hepatitis E Gabonese Republic 2722.20(2077.84,3524.73) 535.68(408.88,693.60) 4286.23(3336.56,5576.32) 518.26(403.43,674.24) −0.11(−0.15,−0.07) 14.44(4.14,34.25) 2.84(0.82,6.74) 7.28(3.58,12.27) 0.88(0.43,1.48) −3.44(−3.61,−3.26)
Acute hepatitis E Georgia 6396.71(4820.87,8432.40) 356.00(268.30,469.30) 3318.61(2489.84,4335.53) 357.11(267.93,466.54) −0.01(−0.08,0.05) 23.08(10.89,38.13) 1.28(0.61,2.12) 4.53(2.88,7.12) 0.49(0.31,0.77) −2.23(−2.75,−1.71)
Acute hepatitis E Grand Duchy of Luxembourg 91.20(69.49,116.57) 103.37(78.75,132.11) 137.88(104.98,178.83) 102.20(77.81,132.54) −0.12(−0.16,−0.09) 0.13(0.09,0.19) 0.15(0.11,0.22) 0.21(0.14,0.30) 0.15(0.10,0.22) 0.24(−0.01,0.49)
Acute hepatitis E Greenland 26.12(19.84,33.18) 145.98(110.89,185.44) 21.75(16.44,28.00) 141.49(106.93,182.20) −0.24(−0.31,−0.17) 0.14(0.08,0.31) 0.80(0.44,1.75) 0.04(0.02,0.06) 0.24(0.14,0.40) −4.46(−4.94,−3.98)
Acute hepatitis E Grenada 171.62(126.83,224.63) 407.08(300.84,532.81) 114.71(86.99,153.01) 381.04(288.97,508.27) −0.21(−0.23,−0.18) 0.29(0.16,0.47) 0.68(0.38,1.12) 0.17(0.09,0.30) 0.58(0.30,0.99) −0.34(−0.55,−0.14)
Acute hepatitis E Guam 203.73(155.57,260.66) 376.27(287.32,481.42) 176.61(135.85,235.11) 364.25(280.18,484.92) −0.18(−0.22,−0.15) 0.32(0.19,0.52) 0.59(0.36,0.95) 0.25(0.14,0.42) 0.51(0.29,0.87) 0.51(−0.07,1.10)
Acute hepatitis E Hashemite Kingdom of Jordan 3904.20(2962.73,5109.84) 186.21(141.31,243.72) 8687.38(6565.71,11461.93) 176.39(133.31,232.73) −0.15(−0.22,−0.09) 42.86(19.48,85.52) 2.04(0.93,4.08) 30.82(18.04,48.66) 0.63(0.37,0.99) −4.02(−4.14,−3.89)
Acute hepatitis E Hellenic Republic 2637.90(2081.63,3295.56) 93.86(74.06,117.26) 1932.37(1501.11,2483.86) 101.42(78.79,130.37) 0.43(0.33,0.53) 4.22(2.92,6.10) 0.15(0.10,0.22) 7.61(5.22,10.68) 0.40(0.27,0.56) 4.68(4.15,5.20)
Acute hepatitis E Hungary 11,964.39(9068.34,15541.14) 412.25(312.46,535.49) 7514.03(5683.37,10024.99) 400.67(303.05,534.56) −0.04(−0.08,−0.01) 31.80(22.10,45.15) 1.10(0.76,1.56) 12.05(7.38,19.86) 0.64(0.39,1.06) −0.99(−1.33,−0.65)
Acute hepatitis E Independent State of Papua New Guinea 9959.29(7676.22,13129.73) 467.87(360.62,616.81) 22,921.29(17311.06,29717.54) 467.87(353.36,606.60) −0.03(−0.06,−0.01) 109.72(34.17,296.70) 5.15(1.61,13.94) 87.60(37.55,199.42) 1.79(0.77,4.07) −3.83(−3.99,−3.67)
Acute hepatitis E Independent State of Samoa 351.05(267.51,449.93) 383.26(292.06,491.21) 379.49(295.57,494.36) 375.95(292.81,489.74) −0.10(−0.11,−0.08) 0.78(0.46,1.24) 0.85(0.50,1.36) 0.62(0.36,1.04) 0.62(0.36,1.03) −1.13(−1.21,−1.05)
Acute hepatitis E Ireland 1352.05(1052.89,1764.22) 101.75(79.24,132.77) 1332.95(1029.96,1729.20) 100.86(77.93,130.84) 0.18(0.10,0.25) 1.68(1.07,2.55) 0.13(0.08,0.19) 1.76(1.14,2.70) 0.13(0.09,0.20) 0.01(−0.40,0.43)
Acute hepatitis E Islamic Republic of Afghanistan 12,445.82(9355.14,16304.31) 223.33(167.87,292.56) 40,035.56(30152.87,52986.31) 225.21(169.62,298.07) −0.07(−0.13,0.00) 1211.31(216.31,4296.65) 21.74(3.88,77.10) 1210.16(337.94,3063.38) 6.81(1.90,17.23) −4.61(−5.02,−4.20)
Acute hepatitis E Islamic Republic of Iran 90,362.21(68433.95,118302.63) 286.78(217.18,375.45) 71,235.38(52846.21,94697.86) 275.52(204.40,366.27) −0.09(−0.46,0.29) 1157.82(629.13,1871.07) 3.67(2.00,5.94) 131.65(78.47,189.02) 0.51(0.30,0.73) −6.74(−7.42,−6.06)
Acute hepatitis E Islamic Republic of Mauritania 3881.42(3025.41,5058.93) 342.30(266.81,446.14) 8000.88(6091.30,10408.72) 343.07(261.19,446.31) −0.02(−0.04,−0.00) 78.39(11.70,356.63) 6.91(1.03,31.45) 19.13(9.42,37.52) 0.82(0.40,1.61) −6.89(−7.15,−6.64)
Acute hepatitis E Islamic Republic of Pakistan 363,766.08(279931.70,469664.43) 596.70(459.18,770.40) 638,711.12(494209.89,833366.63) 584.77(452.47,762.99) −0.05(−0.06,−0.04) 6605.44(1469.75,22885.83) 10.84(2.41,37.54) 12,025.31(3376.45,28120.81) 11.01(3.09,25.75) 1.58(0.99,2.17)
Acute hepatitis E Jamaica 4418.89(3331.17,5906.42) 404.47(304.91,540.63) 3150.53(2361.70,4167.87) 386.39(289.65,511.17) −0.16(−0.17,−0.15) 5.64(2.69,10.21) 0.52(0.25,0.93) 4.42(2.11,8.03) 0.54(0.26,0.99) 0.23(0.16,0.30)
Acute hepatitis E Japan 98,171.90(76023.18,127262.93) 294.25(227.86,381.44) 63,666.24(48689.61,82254.98) 299.84(229.31,387.39) 0.07(0.06,0.09) 280.67(226.73,355.56) 0.84(0.68,1.07) 122.10(87.48,174.32) 0.58(0.41,0.82) −1.71(−2.06,−1.37)
Acute hepatitis E Kingdom of Bahrain 378.95(285.26,492.94) 189.38(142.56,246.35) 721.34(536.05,954.85) 178.76(132.84,236.63) −0.19(−0.21,−0.17) 9.69(4.53,16.43) 4.84(2.27,8.21) 2.79(1.45,5.02) 0.69(0.36,1.24) −7.16(−7.77,−6.55)
Acute hepatitis E Kingdom of Belgium 7181.70(5373.65,9346.20) 290.56(217.41,378.13) 7462.90(5409.52,9911.65) 293.32(212.62,389.57) 0.11(0.07,0.15) 8.07(4.81,13.18) 0.33(0.19,0.53) 10.06(6.30,15.78) 0.40(0.25,0.62) 0.88(0.76,1.01)
Acute hepatitis E Kingdom of Bhutan 549.19(465.54,639.33) 161.24(136.68,187.70) 521.56(403.87,677.68) 204.55(158.39,265.78) 1.18(0.89,1.47) 16.74(2.36,66.65) 4.92(0.69,19.57) 16.36(4.37,36.85) 6.42(1.71,14.45) 1.04(0.16,1.92)
Acute hepatitis E Kingdom of Cambodia 19,472.88(14818.12,25196.56) 342.02(260.27,442.56) 21,476.78(16529.14,27795.96) 323.88(249.27,419.18) −0.26(−0.32,−0.20) 291.07(86.65,601.89) 5.11(1.52,10.57) 125.51(63.61,214.37) 1.89(0.96,3.23) −3.92(−4.32,−3.52)
Acute hepatitis E Kingdom of Denmark 1228.47(944.91,1577.27) 98.26(75.58,126.15) 1288.17(988.40,1669.09) 99.53(76.37,128.97) −0.07(−0.14,0.00) 1.56(0.96,2.37) 0.12(0.08,0.19) 2.19(1.49,3.24) 0.17(0.12,0.25) 0.86(0.43,1.30)
Acute hepatitis E Kingdom of Eswatini 1854.37(1409.22,2392.13) 388.65(295.36,501.36) 2031.76(1579.70,2657.68) 379.76(295.27,496.76) −0.06(−0.08,−0.04) 7.78(3.44,16.94) 1.63(0.72,3.55) 5.07(2.87,8.36) 0.95(0.54,1.56) −1.79(−1.97,−1.61)
Acute hepatitis E Kingdom of Lesotho 3293.07(2489.48,4292.60) 393.29(297.31,512.66) 3225.32(2450.79,4276.89) 384.51(292.17,509.87) −0.04(−0.06,−0.02) 14.92(5.82,37.04) 1.78(0.70,4.42) 10.62(5.24,18.80) 1.27(0.62,2.24) −1.08(−1.21,−0.94)
Acute hepatitis E Kingdom of Morocco 24,371.85(18348.38,32162.30) 195.29(147.02,257.71) 23,753.33(17650.22,31337.25) 183.91(136.66,242.63) −0.19(−0.22,−0.17) 277.93(124.87,597.53) 2.23(1.00,4.79) 106.95(44.98,230.95) 0.83(0.35,1.79) −3.21(−3.32,−3.10)
Acute hepatitis E Kingdom of Norway 1388.85(1081.86,1776.55) 124.84(97.24,159.68) 1521.30(1179.43,1955.77) 122.54(95.00,157.54) −0.09(−0.12,−0.06) 1.55(0.92,2.49) 0.14(0.08,0.22) 1.71(1.03,2.81) 0.14(0.08,0.23) −0.02(−0.14,0.11)
Acute hepatitis E Kingdom of Saudi Arabia 34,781.65(25403.84,45267.72) 423.58(309.37,551.28) 33,853.58(24637.55,45597.06) 334.08(243.13,449.97) −0.87(−1.02,−0.71) 331.63(160.99,606.85) 4.04(1.96,7.39) 56.26(29.57,93.02) 0.56(0.29,0.92) −5.92(−6.63,−5.20)
Acute hepatitis E Kingdom of Spain 9860.93(7654.55,13053.61) 88.46(68.67,117.10) 7153.61(5550.08,9312.26) 81.22(63.02,105.73) 0.66(0.28,1.03) 16.60(11.34,24.17) 0.15(0.10,0.22) 14.24(10.52,19.86) 0.16(0.12,0.23) 1.24(0.78,1.70)
Acute hepatitis E Kingdom of Sweden 2638.26(2048.79,3350.20) 125.21(97.24,159.00) 3005.44(2338.88,3854.35) 124.43(96.84,159.58) −0.02(−0.10,0.06) 2.95(1.78,4.67) 0.14(0.08,0.22) 3.53(2.24,5.70) 0.15(0.09,0.24) 0.11(−0.02,0.23)
Acute hepatitis E Kingdom of Thailand 65,285.05(49025.39,84939.12) 287.01(215.53,373.41) 37,319.69(28137.68,49294.29) 273.44(206.16,361.18) 0.09(−0.01,0.18) 154.96(87.81,242.47) 0.68(0.39,1.07) 94.79(57.70,138.26) 0.69(0.42,1.01) 0.81(0.47,1.16)
Acute hepatitis E Kingdom of the Netherlands 3027.09(2326.88,3875.93) 78.97(60.71,101.12) 3067.77(2326.58,3936.40) 83.11(63.03,106.65) −0.03(−0.28,0.21) 5.25(3.76,7.32) 0.14(0.10,0.19) 6.18(4.47,8.50) 0.17(0.12,0.23) 0.99(0.58,1.41)
Acute hepatitis E Kingdom of Tonga 214.07(162.60,275.79) 401.16(304.70,516.83) 191.72(145.15,247.43) 386.68(292.75,499.04) −0.13(−0.15,−0.10) 7.21(3.21,14.80) 13.51(6.01,27.73) 2.99(1.23,6.79) 6.03(2.48,13.70) −2.89(−3.24,−2.55)
Acute hepatitis E Kyrgyz Republic 7928.44(6144.46,10343.12) 375.51(291.02,489.87) 10,425.53(7846.98,13775.98) 369.33(277.98,488.02) −0.10(−0.17,−0.04) 78.57(51.43,125.34) 3.72(2.44,5.94) 18.02(11.50,27.21) 0.64(0.41,0.96) −5.13(−6.08,−4.17)
Acute hepatitis E Lao People’s Democratic Republic 7693.62(5924.62,9974.25) 339.15(261.17,439.69) 9878.34(7343.92,12859.40) 330.21(245.49,429.86) −0.18(−0.22,−0.14) 124.99(27.08,494.19) 5.51(1.19,21.78) 42.58(20.39,75.65) 1.42(0.68,2.53) −5.01(−5.42,−4.60)
Acute hepatitis E Lebanese Republic 2018.98(1548.23,2609.54) 150.77(115.61,194.87) 2402.40(1808.08,3200.43) 144.18(108.51,192.08) −0.06(−0.12,0.00) 16.59(7.15,29.63) 1.24(0.53,2.21) 9.58(5.72,14.89) 0.57(0.34,0.89) −2.51(−2.61,−2.40)
Acute hepatitis E Malaysia 23,094.31(17571.79,29849.37) 276.81(210.62,357.78) 26,984.80(20517.89,34870.25) 263.13(200.07,340.02) −0.20(−0.24,−0.17) 50.62(30.34,75.21) 0.61(0.36,0.90) 42.00(27.03,65.11) 0.41(0.26,0.63) −1.17(−1.30,−1.05)
Acute hepatitis E Mongolia 4324.69(3301.45,5613.82) 380.99(290.85,494.56) 5077.77(3845.28,6619.39) 386.82(292.93,504.26) 0.08(−0.16,0.33) 9.70(4.48,19.39) 0.85(0.39,1.71) 6.96(3.89,11.70) 0.53(0.30,0.89) −1.11(−1.48,−0.74)
Acute hepatitis E Montenegro 904.05(688.63,1180.19) 421.43(321.01,550.16) 613.92(461.66,809.30) 408.22(306.97,538.14) −0.14(−0.16,−0.12) 1.37(0.72,2.29) 0.64(0.33,1.07) 0.74(0.38,1.34) 0.49(0.25,0.89) −1.08(−1.17,−0.98)
Acute hepatitis E New Zealand 1793.68(1373.73,2317.98) 162.90(124.76,210.52) 2191.03(1658.67,2833.26) 168.09(127.25,217.36) −0.01(−0.05,0.03) 2.21(1.39,3.49) 0.20(0.13,0.32) 2.30(1.35,3.90) 0.18(0.10,0.30) −0.32(−0.39,−0.24)
Acute hepatitis E North Macedonia 2950.92(2252.09,3902.65) 423.41(323.14,559.97) 1807.01(1357.59,2420.18) 404.65(304.01,541.96) −0.21(−0.27,−0.15) 22.22(7.35,45.15) 3.19(1.05,6.48) 3.33(1.57,6.29) 0.75(0.35,1.41) −3.76(−4.46,−3.06)
Acute hepatitis E Northern Mariana Islands 60.22(45.11,76.76) 371.38(278.16,473.37) 54.68(41.50,72.99) 364.62(276.73,486.71) −0.21(−0.26,−0.15) 0.15(0.09,0.25) 0.93(0.55,1.53) 0.11(0.06,0.17) 0.70(0.40,1.14) −0.79(−1.19,−0.39)
Acute hepatitis E Palestine 2383.02(1774.73,3152.20) 199.65(148.69,264.10) 4464.82(3280.63,5982.11) 185.43(136.25,248.44) −0.23(−0.24,−0.21) 23.76(10.69,44.28) 1.99(0.90,3.71) 12.90(7.83,19.66) 0.54(0.33,0.82) −4.11(−4.31,−3.91)
Acute hepatitis E People’s Democratic Republic of Algeria 25,825.84(19246.40,34354.79) 191.07(142.39,254.17) 30,548.92(22380.04,40809.33) 185.72(136.06,248.10) −0.07(−0.12,−0.01) 427.05(186.55,923.32) 3.16(1.38,6.83) 129.00(70.00,227.85) 0.78(0.43,1.39) −3.90(−4.13,−3.67)
Acute hepatitis E People’s Republic of Bangladesh 520,628.99(422758.54,634095.45) 862.55(700.40,1050.54) 530,992.69(424232.89,653605.96) 870.64(695.59,1071.68) −0.15(−0.38,0.08) 2271.49(747.57,7110.43) 3.76(1.24,11.78) 1777.41(694.81,4517.16) 2.91(1.14,7.41) −0.63(−0.80,−0.47)
Acute hepatitis E People’s Republic of China 3,421,039.54(2658245.68,4346608.41) 768.70(597.30,976.67) 2,436,265.10(1878997.34,3105406.29) 728.76(562.06,928.92) −0.37(−0.52,−0.23) 14,619.67(5730.01,22768.40) 3.29(1.29,5.12) 3019.06(1817.12,4879.50) 0.90(0.54,1.46) −4.75(−5.17,−4.32)
Acute hepatitis E Plurinational State of Bolivia 13,785.13(10572.12,17907.66) 411.64(315.69,534.74) 17,917.49(13542.71,23551.91) 394.07(297.85,517.99) −0.20(−0.21,−0.18) 22.51(10.86,41.13) 0.67(0.32,1.23) 25.54(13.66,41.74) 0.56(0.30,0.92) −0.57(−0.60,−0.53)
Acute hepatitis E Portuguese Republic 2881.21(2176.84,3792.43) 96.65(73.02,127.22) 1807.82(1378.85,2382.70) 94.32(71.94,124.31) 0.03(−0.05,0.12) 4.12(2.66,6.23) 0.14(0.09,0.21) 3.89(2.50,6.04) 0.20(0.13,0.32) 1.81(1.46,2.16)
Acute hepatitis E Principality of Andorra 13.07(10.13,16.92) 97.15(75.28,125.68) 13.45(10.27,17.65) 93.51(71.46,122.73) −0.08(−0.18,0.02) 0.49(0.20,1.13) 3.65(1.46,8.40) 0.12(0.05,0.34) 0.86(0.32,2.34) −4.27(−4.66,−3.89)
Acute hepatitis E Principality of Monaco 4.94(3.77,6.37) 102.01(77.83,131.43) 6.73(5.13,8.71) 99.38(75.77,128.69) −0.12(−0.14,−0.10) 0.01(0.00,0.01) 0.13(0.08,0.21) 0.01(0.01,0.01) 0.14(0.08,0.22) −0.17(−0.32,−0.02)
Acute hepatitis E Puerto Rico 5069.38(3768.27,6725.67) 380.56(282.88,504.90) 2408.91(1781.06,3280.43) 368.63(272.55,501.99) −0.07(−0.08,−0.06) 7.03(3.45,12.90) 0.53(0.26,0.97) 3.37(1.61,6.34) 0.52(0.25,0.97) 0.10(0.02,0.18)
Acute hepatitis E Republic of Albania 6412.76(4900.42,8561.76) 443.51(338.92,592.14) 2577.69(1958.47,3360.04) 417.70(317.36,544.47) −0.11(−0.23,0.02) 109.10(22.70,207.14) 7.55(1.57,14.33) 13.25(5.00,33.16) 2.15(0.81,5.37) −4.01(−4.38,−3.63)
Acute hepatitis E Republic of Angola 31,089.50(24363.18,39940.83) 539.18(422.53,692.69) 100,291.82(76692.92,130316.91) 537.02(410.66,697.79) −0.01(−0.03,0.01) 864.82(102.50,2680.28) 15.00(1.78,46.48) 464.91(148.33,1413.38) 2.49(0.79,7.57) −5.46(−5.96,−4.95)
Acute hepatitis E Republic of Armenia 4803.47(3691.53,6142.88) 361.76(278.01,462.63) 2630.34(1988.45,3443.66) 344.68(260.57,451.26) −0.18(−0.30,−0.05) 15.81(10.56,23.69) 1.19(0.80,1.78) 3.12(1.88,5.15) 0.41(0.25,0.67) −3.10(−3.46,−2.73)
Acute hepatitis E Republic of Austria 1908.09(1455.26,2456.73) 101.86(77.69,131.15) 1793.36(1367.24,2293.83) 102.19(77.91,130.71) −0.05(−0.10,−0.01) 2.64(1.72,3.97) 0.14(0.09,0.21) 3.28(2.32,4.58) 0.19(0.13,0.26) 1.29(0.98,1.60)
Acute hepatitis E Republic of Azerbaijan 11,741.66(9012.35,15229.87) 375.12(287.93,486.56) 10,895.68(8146.73,14530.71) 357.61(267.39,476.92) −0.26(−0.34,−0.18) 317.39(105.13,716.55) 10.14(3.36,22.89) 45.25(21.82,99.20) 1.49(0.72,3.26) −5.44(−6.19,−4.69)
Acute hepatitis E Republic of Belarus 6729.14(5070.19,8693.57) 214.44(161.57,277.04) 4205.26(3089.26,5589.74) 207.64(152.54,276.00) −0.01(−0.14,0.11) 41.01(26.17,67.55) 1.31(0.83,2.15) 13.79(8.74,20.15) 0.68(0.43,0.99) −1.16(−1.42,−0.90)
Acute hepatitis E Republic of Benin 10,815.11(8255.33,14110.07) 376.87(287.67,491.69) 27,870.86(20847.66,36963.23) 370.81(277.37,491.77) −0.10(−0.12,−0.08) 165.73(50.33,325.68) 5.78(1.75,11.35) 93.59(45.34,164.07) 1.25(0.60,2.18) −5.05(−5.13,−4.96)
Acute hepatitis E Republic of Botswana 2875.45(2191.47,3778.62) 388.33(295.96,510.30) 3412.81(2598.07,4474.01) 372.17(283.32,487.89) −0.11(−0.13,−0.10) 8.45(3.96,15.90) 1.14(0.53,2.15) 6.55(3.83,10.36) 0.71(0.42,1.13) −1.49(−1.61,−1.38)
Acute hepatitis E Republic of Bulgaria 9744.40(7544.35,12850.80) 412.32(319.23,543.77) 5223.68(4023.10,6920.01) 403.60(310.84,534.66) 0.02(−0.04,0.09) 35.34(22.79,49.43) 1.50(0.96,2.09) 15.42(9.95,22.16) 1.19(0.77,1.71) −0.35(−0.73,0.03)
Acute hepatitis E Republic of Burundi 16,272.45(13075.66,19964.20) 515.75(414.43,632.75) 39,842.82(30570.86,52170.21) 547.70(420.24,717.16) 0.19(0.12,0.26) 103.17(26.13,323.95) 3.27(0.83,10.27) 165.08(56.42,435.20) 2.27(0.78,5.98) −0.14(−0.53,0.25)
Acute hepatitis E Republic of Cabo Verde 678.17(508.63,886.34) 348.72(261.55,455.77) 629.36(486.48,826.19) 326.52(252.39,428.64) −0.27(−0.30,−0.24) 1.79(0.86,3.19) 0.92(0.44,1.64) 0.96(0.58,1.54) 0.50(0.30,0.80) −2.71(−3.03,−2.38)
Acute hepatitis E Republic of Cameroon 22,023.53(16779.81,28593.41) 370.95(282.63,481.61) 62,060.13(47084.15,80348.85) 367.16(278.56,475.36) −0.04(−0.06,−0.02) 121.52(52.96,269.33) 2.05(0.89,4.54) 134.12(71.87,237.04) 0.79(0.43,1.40) −2.76(−2.95,−2.57)
Acute hepatitis E Republic of Chad 13,984.23(10582.88,18023.92) 396.68(300.20,511.28) 43,352.11(32813.71,56257.60) 395.93(299.68,513.79) 0.01(−0.02,0.04) 343.78(82.22,931.53) 9.75(2.33,26.42) 362.65(122.33,800.72) 3.31(1.12,7.31) −3.45(−3.60,−3.29)
Acute hepatitis E Republic of Chile 7196.98(5713.17,8833.74) 136.45(108.32,167.48) 5981.96(4541.48,7811.08) 122.24(92.80,159.61) −0.37(−0.46,−0.28) 10.08(6.54,14.84) 0.19(0.12,0.28) 7.01(4.26,11.82) 0.14(0.09,0.24) −0.93(−1.06,−0.80)
Acute hepatitis E Republic of Colombia 31,025.73(23100.80,40634.17) 206.11(153.46,269.94) 27,568.06(20905.53,36493.68) 189.35(143.59,250.65) −0.36(−0.38,−0.33) 99.21(69.69,133.96) 0.66(0.46,0.89) 42.24(27.38,64.78) 0.29(0.19,0.44) −2.85(−3.25,−2.45)
Acute hepatitis E Republic of Costa Rica 2903.04(2205.90,3776.45) 204.71(155.55,266.29) 2546.27(1962.71,3344.22) 186.00(143.37,244.29) −0.28(−0.35,−0.22) 8.52(5.56,12.46) 0.60(0.39,0.88) 5.31(3.45,7.70) 0.39(0.25,0.56) −1.61(−1.95,−1.28)
Acute hepatitis E Republic of Croatia 5433.38(4086.75,7193.87) 409.62(308.10,542.34) 3211.30(2442.48,4241.28) 398.56(303.14,526.39) −0.10(−0.12,−0.07) 6.55(3.31,11.49) 0.49(0.25,0.87) 3.81(1.96,6.83) 0.47(0.24,0.85) −0.22(−0.30,−0.13)
Acute hepatitis E Republic of Cuba 14,209.58(10688.04,18945.85) 389.09(292.66,518.78) 9189.44(6972.90,12214.02) 382.70(290.39,508.66) 0.08(−0.25,0.42) 18.56(8.69,33.57) 0.51(0.24,0.92) 11.48(5.42,20.84) 0.48(0.23,0.87) 0.07(−0.13,0.27)
Acute hepatitis E Republic of Cyprus 270.87(205.26,347.01) 104.56(79.23,133.95) 295.09(222.86,378.90) 103.51(78.17,132.91) 0.04(−0.05,0.13) 0.40(0.25,0.66) 0.16(0.09,0.25) 0.33(0.20,0.53) 0.11(0.07,0.19) −0.73(−0.84,−0.62)
Acute hepatitis E Republic of C么te d’Ivoire 26,426.51(19866.10,34543.99) 381.97(287.14,499.30) 54,488.59(41500.95,70559.23) 378.80(288.51,490.52) −0.05(−0.06,−0.04) 313.40(99.14,642.75) 4.53(1.43,9.29) 140.43(75.53,241.87) 0.98(0.53,1.68) −4.65(−4.86,−4.44)
Acute hepatitis E Republic of Djibouti 1256.03(974.26,1603.84) 560.04(434.41,715.13) 2907.10(2224.67,3725.18) 550.20(421.04,705.03) −0.04(−0.05,−0.02) 11.60(2.62,33.37) 5.17(1.17,14.88) 15.28(5.70,34.26) 2.89(1.08,6.48) −1.63(−1.83,−1.42)
Acute hepatitis E Republic of Ecuador 20,279.03(15639.17,26198.77) 409.06(315.46,528.46) 26,091.49(19604.04,33059.75) 394.35(296.30,499.67) −0.18(−0.20,−0.16) 30.17(17.55,48.70) 0.61(0.35,0.98) 30.69(16.18,55.72) 0.46(0.24,0.84) −1.03(−1.23,−0.83)
Acute hepatitis E Republic of El Salvador 5911.19(4391.70,7654.08) 214.53(159.39,277.79) 4770.02(3543.03,6269.38) 200.25(148.74,263.19) −0.27(−0.32,−0.21) 39.93(17.27,74.12) 1.45(0.63,2.69) 10.81(5.80,18.24) 0.45(0.24,0.77) −4.29(−4.71,−3.87)
Acute hepatitis E Republic of Equatorial Guinea 1293.85(986.82,1646.54) 539.15(411.21,686.11) 3869.78(2947.04,4961.98) 502.48(382.67,644.30) −0.29(−0.32,−0.27) 2.64(1.11,7.52) 1.10(0.46,3.13) 6.02(2.92,10.73) 0.78(0.38,1.39) −1.27(−1.48,−1.06)
Acute hepatitis E Republic of Estonia 959.77(729.02,1248.86) 208.95(158.72,271.89) 570.23(417.41,750.24) 203.43(148.91,267.65) 0.07(−0.05,0.19) 2.70(1.82,3.98) 0.59(0.40,0.87) 0.70(0.44,1.14) 0.25(0.16,0.41) −2.23(−2.87,−1.59)
Acute hepatitis E Republic of Fiji 1439.11(1099.43,1847.26) 401.19(306.50,514.98) 1336.06(1038.51,1778.72) 381.05(296.18,507.29) −0.14(−0.17,−0.10) 6.90(3.19,13.24) 1.92(0.89,3.69) 3.71(2.10,6.13) 1.06(0.60,1.75) −2.45(−2.78,−2.12)
Acute hepatitis E Republic of Finland 1312.99(1015.54,1696.84) 103.49(80.04,133.74) 1122.10(858.99,1453.99) 97.70(74.79,126.60) −0.10(−0.14,−0.06) 1.29(0.70,2.17) 0.10(0.06,0.17) 1.30(0.79,2.11) 0.11(0.07,0.18) 0.31(0.23,0.40)
Acute hepatitis E Republic of Ghana 26,428.31(20754.31,33305.32) 319.97(251.28,403.23) 55,099.56(41976.51,72541.02) 337.74(257.30,444.65) 0.18(0.10,0.27) 1006.78(446.64,1947.17) 12.19(5.41,23.57) 322.48(141.37,594.16) 1.98(0.87,3.64) −5.63(−5.78,−5.47)
Acute hepatitis E Republic of Guatemala 11,036.85(8164.57,14204.97) 224.75(166.26,289.26) 13,270.29(9885.49,17411.38) 200.61(149.44,263.21) −0.36(−0.37,−0.34) 37.02(21.18,64.25) 0.75(0.43,1.31) 37.93(22.31,60.46) 0.57(0.34,0.91) −0.83(−1.13,−0.53)
Acute hepatitis E Republic of Guinea 13,052.28(10080.95,16865.11) 397.07(306.67,513.06) 29,190.10(21900.87,38133.92) 391.05(293.40,510.87) −0.06(−0.08,−0.04) 463.44(84.83,1153.99) 14.10(2.58,35.11) 164.99(64.04,345.50) 2.21(0.86,4.63) −5.45(−5.69,−5.22)
Acute hepatitis E Republic of Guinea−Bissau 2319.39(1766.07,2942.02) 394.39(300.30,500.26) 4421.49(3353.50,5819.00) 395.30(299.81,520.24) −0.02(−0.04,−0.01) 51.80(11.17,127.24) 8.81(1.90,21.64) 17.24(8.02,33.64) 1.54(0.72,3.01) −5.46(−5.64,−5.28)
Acute hepatitis E Republic of Guyana 1534.29(1151.67,2005.42) 402.08(301.81,525.55) 1095.37(824.41,1443.85) 390.21(293.69,514.35) −0.10(−0.14,−0.05) 4.87(3.21,6.98) 1.28(0.84,1.83) 3.60(2.20,5.39) 1.28(0.78,1.92) 0.60(−0.08,1.27)
Acute hepatitis E Republic of Haiti 13,877.86(10380.81,18380.86) 414.71(310.21,549.27) 22,827.52(17401.69,30693.75) 407.07(310.32,547.35) −0.07(−0.08,−0.06) 34.57(13.60,95.79) 1.03(0.41,2.86) 54.44(25.63,105.28) 0.97(0.46,1.88) −0.26(−0.34,−0.19)
Acute hepatitis E Republic of Honduras 5879.45(4437.49,7553.40) 216.67(163.53,278.35) 8676.03(6424.38,11256.05) 199.43(147.67,258.73) −0.30(−0.31,−0.29) 87.59(13.01,213.38) 3.23(0.48,7.86) 38.43(14.69,83.00) 0.88(0.34,1.91) −4.39(−4.89,−3.88)
Acute hepatitis E Republic of Iceland 87.74(68.44,112.90) 103.81(80.98,133.59) 90.02(68.63,116.49) 101.03(77.02,130.74) −0.02(−0.04,0.01) 0.11(0.07,0.17) 0.13(0.08,0.20) 0.16(0.12,0.23) 0.18(0.13,0.25) 1.15(0.84,1.46)
Acute hepatitis E Republic of India 2,994,454.74(2332973.37,3808277.08) 729.61(568.44,927.91) 3,696,461.01(2893211.09,4703425.58) 738.45(577.98,939.61) 0.01(−0.01,0.04) 46,667.60(17077.07,112869.39) 11.37(4.16,27.50) 89,512.42(39888.39,173915.96) 17.88(7.97,34.74) 2.03(1.68,2.38)
Acute hepatitis E Republic of Indonesia 336,411.39(256546.52,437104.00) 384.63(293.32,499.76) 338,625.33(255938.18,439361.22) 375.34(283.69,487.00) 0.19(0.08,0.31) 4249.26(1941.01,7467.55) 4.86(2.22,8.54) 2518.38(1363.95,3867.71) 2.79(1.51,4.29) −2.42(−2.72,−2.12)
Acute hepatitis E Republic of Iraq 20,086.68(14918.97,25849.79) 195.04(144.87,251.00) 32,437.74(24443.19,43548.29) 183.92(138.59,246.92) −0.15(−0.19,−0.11) 267.57(111.03,517.39) 2.60(1.08,5.02) 224.13(113.88,390.18) 1.27(0.65,2.21) −2.08(−2.19,−1.98)
Acute hepatitis E Republic of Italy 17,862.11(13732.49,22860.32) 131.15(100.83,167.85) 15,038.05(11350.80,19316.86) 143.50(108.31,184.33) 0.61(0.43,0.79) 37.60(28.60,51.50) 0.28(0.21,0.38) 23.14(15.29,34.26) 0.22(0.15,0.33) −0.47(−0.63,−0.32)
Acute hepatitis E Republic of Kazakhstan 24,729.71(18885.06,32526.49) 372.26(284.28,489.63) 24,222.68(18441.91,32108.75) 360.24(274.27,477.52) −0.07(−0.17,0.03) 224.60(133.08,360.36) 3.38(2.00,5.42) 45.13(29.24,67.55) 0.67(0.43,1.00) −5.11(−5.91,−4.30)
Acute hepatitis E Republic of Kenya 90,401.16(70043.28,114548.74) 655.47(507.86,830.55) 153,676.62(119501.73,196678.82) 624.69(485.77,799.49) −0.10(−0.13,−0.07) 925.74(258.44,2129.28) 6.71(1.87,15.44) 952.21(391.14,2076.87) 3.87(1.59,8.44) −1.40(−1.65,−1.15)
Acute hepatitis E Republic of Kiribati 152.31(116.79,191.44) 415.55(318.62,522.31) 216.63(164.54,275.30) 405.34(307.88,515.10) −0.11(−0.14,−0.07) 1.19(0.64,2.32) 3.24(1.74,6.33) 1.28(0.65,2.88) 2.40(1.21,5.39) −0.84(−0.97,−0.72)
Acute hepatitis E Republic of Korea 30,953.99(23748.66,41466.14) 194.35(149.11,260.35) 15,152.61(11676.03,19927.66) 180.75(139.28,237.71) −0.26(−0.42,−0.10) 75.93(43.41,131.75) 0.48(0.27,0.83) 22.35(13.72,37.00) 0.27(0.16,0.44) −2.32(−2.68,−1.95)
Acute hepatitis E Republic of Latvia 1592.18(1203.97,2085.00) 211.61(160.01,277.11) 796.49(599.65,1041.28) 205.77(154.91,269.01) 0.02(−0.12,0.16) 11.06(7.57,16.20) 1.47(1.01,2.15) 1.93(1.21,2.82) 0.50(0.31,0.73) −2.14(−3.13,−1.15)
Acute hepatitis E Republic of Liberia 5370.33(4068.01,6890.62) 393.10(297.77,504.38) 10,868.82(8284.35,13995.14) 389.56(296.93,501.61) −0.02(−0.05,0.01) 108.74(23.56,263.36) 7.96(1.72,19.28) 39.48(19.26,76.74) 1.41(0.69,2.75) −5.86(−6.16,−5.55)
Acute hepatitis E Republic of Lithuania 2305.20(1743.96,2989.85) 208.12(157.45,269.93) 1100.25(806.76,1457.62) 205.35(150.57,272.05) −0.06(−0.16,0.04) 12.73(8.42,18.32) 1.15(0.76,1.65) 1.53(1.00,2.38) 0.29(0.19,0.44) −3.66(−4.86,−2.45)
Acute hepatitis E Republic of Madagascar 36,263.06(28032.12,47038.44) 539.15(416.77,699.35) 79,392.18(60784.38,103182.42) 531.27(406.75,690.47) −0.01(−0.04,0.01) 291.24(66.26,761.62) 4.33(0.99,11.32) 347.12(128.22,874.82) 2.32(0.86,5.85) −1.72(−1.95,−1.48)
Acute hepatitis E Republic of Malawi 28,192.40(22027.62,37315.39) 505.85(395.24,669.54) 51,576.39(38827.33,67132.28) 486.99(366.61,633.87) −0.05(−0.08,−0.02) 221.98(55.68,551.76) 3.98(1.00,9.90) 258.71(98.21,661.66) 2.44(0.93,6.25) −1.70(−1.98,−1.42)
Acute hepatitis E Republic of Maldives 391.28(294.12,509.39) 304.87(229.17,396.90) 367.71(279.96,475.03) 282.19(214.85,364.55) −0.27(−0.38,−0.17) 2.64(0.97,5.64) 2.06(0.76,4.39) 1.00(0.61,1.46) 0.77(0.47,1.12) −3.13(−3.36,−2.89)
Acute hepatitis E Republic of Mali 19,564.20(15066.94,24964.29) 395.57(304.64,504.75) 55,563.29(42048.32,70968.87) 390.38(295.43,498.62) −0.03(−0.05,−0.01) 86.25(39.14,214.67) 1.74(0.79,4.34) 144.42(70.22,290.17) 1.01(0.49,2.04) −1.62(−1.70,−1.54)
Acute hepatitis E Republic of Malta 117.53(89.26,151.12) 101.98(77.45,131.12) 86.87(66.75,109.04) 103.47(79.51,129.88) 0.03(−0.05,0.10) 0.13(0.07,0.20) 0.11(0.06,0.18) 0.13(0.09,0.19) 0.15(0.10,0.23) 1.21(1.03,1.39)
Acute hepatitis E Republic of Mauritius 1163.39(866.56,1514.15) 270.04(201.15,351.46) 751.40(570.25,980.71) 253.08(192.07,330.31) −0.21(−0.23,−0.19) 2.00(1.40,2.90) 0.46(0.33,0.67) 0.99(0.61,1.63) 0.33(0.20,0.55) −1.86(−2.31,−1.41)
Acute hepatitis E Republic of Moldova 7478.32(5532.05,10003.11) 472.93(349.85,632.60) 3142.47(2326.68,4182.43) 451.35(334.18,600.72) −0.14(−0.26,−0.02) 17.20(10.43,26.93) 1.09(0.66,1.70) 4.76(2.55,8.42) 0.68(0.37,1.21) −0.82(−1.26,−0.37)
Acute hepatitis E Republic of Mozambique 39,639.30(30369.82,50527.37) 523.59(401.15,667.41) 91,770.09(70771.96,118863.14) 516.89(398.62,669.50) −0.03(−0.05,−0.01) 499.92(80.46,1491.11) 6.60(1.06,19.70) 429.64(140.57,1111.69) 2.42(0.79,6.26) −3.74(−4.11,−3.37)
Acute hepatitis E Republic of Namibia 2926.46(2226.88,3759.18) 384.21(292.36,493.54) 4032.65(3046.17,5220.29) 376.40(284.32,487.25) −0.05(−0.07,−0.03) 7.45(3.62,13.17) 0.98(0.48,1.73) 7.61(4.15,12.13) 0.71(0.39,1.13) −1.02(−1.07,−0.96)
Acute hepatitis E Republic of Nauru 20.90(15.65,27.26) 401.11(300.27,523.27) 19.40(15.04,24.78) 378.23(293.12,483.20) −0.19(−0.21,−0.16) 0.07(0.04,0.12) 1.35(0.75,2.26) 0.04(0.03,0.07) 0.84(0.49,1.41) −1.75(−2.02,−1.48)
Acute hepatitis E Republic of Nicaragua 4987.10(3829.82,6520.16) 221.62(170.19,289.75) 5208.39(3923.20,6774.31) 200.38(150.94,260.62) −0.36(−0.40,−0.31) 37.24(13.93,83.60) 1.65(0.62,3.72) 15.08(7.75,29.34) 0.58(0.30,1.13) −3.44(−3.73,−3.14)
Acute hepatitis E Republic of Niue 4.02(3.07,5.27) 393.17(300.48,515.89) 1.94(1.50,2.55) 367.79(284.41,482.26) −0.17(−0.21,−0.12) 0.01(0.01,0.02) 1.00(0.58,1.66) 0.01(0.00,0.01) 1.39(0.70,2.82) −0.74(−1.38,−0.10)
Acute hepatitis E Republic of Palau 23.06(17.39,30.74) 374.11(282.01,498.54) 16.20(11.97,21.51) 365.83(270.21,485.67) −0.11(−0.14,−0.07) 0.15(0.07,0.31) 2.47(1.10,5.05) 0.06(0.03,0.10) 1.30(0.68,2.22) −2.03(−2.10,−1.95)
Acute hepatitis E Republic of Panama 2277.94(1730.05,2959.64) 209.56(159.15,272.27) 2962.53(2225.80,3887.47) 196.55(147.67,257.92) −0.22(−0.23,−0.20) 4.49(3.00,6.77) 0.41(0.28,0.62) 5.43(3.55,8.08) 0.36(0.24,0.54) −0.51(−0.66,−0.36)
Acute hepatitis E Republic of Paraguay 2738.21(2098.56,3503.94) 132.34(101.42,169.35) 3208.80(2447.03,4189.92) 120.15(91.63,156.89) −0.29(−0.33,−0.25) 4.91(2.78,8.94) 0.24(0.13,0.43) 4.90(2.97,7.67) 0.18(0.11,0.29) −0.65(−0.91,−0.40)
Acute hepatitis E Republic of Peru 44,199.08(33712.13,58134.90) 415.03(316.55,545.88) 49,379.34(37250.23,63889.99) 394.70(297.75,510.69) −0.21(−0.24,−0.19) 64.03(32.51,106.50) 0.60(0.31,1.00) 59.99(28.57,110.07) 0.48(0.23,0.88) −0.80(−0.88,−0.72)
Acute hepatitis E Republic of Poland 62,843.74(47960.89,82946.69) 504.79(385.24,666.27) 37,105.46(28400.54,48629.79) 481.98(368.90,631.67) −0.08(−0.17,0.01) 111.61(79.54,154.53) 0.90(0.64,1.24) 40.43(22.96,69.44) 0.53(0.30,0.90) −1.86(−2.02,−1.69)
Acute hepatitis E Republic of Rwanda 20,810.90(15804.77,26956.94) 502.84(381.88,651.34) 31,240.05(24089.93,41192.29) 485.24(374.18,639.82) −0.08(−0.10,−0.05) 175.00(46.80,378.49) 4.23(1.13,9.15) 149.02(53.50,323.32) 2.31(0.83,5.02) −2.04(−2.29,−1.80)
Acute hepatitis E Republic of San Marino 2.74(2.04,3.52) 45.78(34.05,58.92) 3.86(2.98,5.00) 61.84(47.69,80.10) 1.02(0.61,1.43) 0.23(0.09,0.50) 3.80(1.45,8.40) 0.08(0.02,0.18) 1.28(0.36,2.96) −4.18(−4.77,−3.59)
Acute hepatitis E Republic of Senegal 15,830.39(12363.88,20528.09) 355.98(278.03,461.62) 28,207.08(21359.50,36664.41) 347.58(263.20,451.79) −0.09(−0.11,−0.08) 86.94(39.12,152.09) 1.96(0.88,3.42) 53.86(27.46,90.22) 0.66(0.34,1.11) −3.61(−3.80,−3.42)
Acute hepatitis E Republic of Serbia 12,091.63(9234.94,15743.93) 416.79(318.33,542.69) 7378.19(5640.45,9637.63) 393.74(301.01,514.32) −0.18(−0.20,−0.17) 15.38(7.66,26.43) 0.53(0.26,0.91) 9.19(4.50,16.83) 0.49(0.24,0.90) −0.35(−0.45,−0.25)
Acute hepatitis E Republic of Seychelles 86.30(64.60,110.14) 276.23(206.79,352.53) 84.39(63.60,111.14) 276.43(208.34,364.07) −0.01(−0.04,0.02) 0.89(0.41,1.68) 2.85(1.32,5.37) 0.29(0.15,0.51) 0.96(0.48,1.68) −2.11(−2.54,−1.67)
Acute hepatitis E Republic of Sierra Leone 9451.34(7117.50,12290.86) 428.49(322.69,557.23) 19,654.35(15028.80,25948.65) 431.90(330.26,570.22) −0.02(−0.04,0.01) 314.76(54.07,887.26) 14.27(2.45,40.23) 89.18(36.38,185.85) 1.96(0.80,4.08) −6.51(−6.66,−6.36)
Acute hepatitis E Republic of Singapore 3571.88(2967.64,4330.77) 387.84(322.23,470.24) 4069.49(3116.22,5323.07) 390.02(298.66,510.17) −0.12(−0.23,−0.01) 5.75(3.57,9.12) 0.62(0.39,0.99) 4.75(2.71,8.20) 0.45(0.26,0.79) −1.54(−1.79,−1.30)
Acute hepatitis E Republic of Slovenia 2270.25(1711.97,2919.88) 407.75(307.48,524.43) 1643.96(1225.51,2154.39) 406.09(302.73,532.18) 0.03(−0.03,0.08) 3.25(1.80,5.38) 0.58(0.32,0.97) 1.85(0.91,3.35) 0.46(0.23,0.83) −0.76(−0.89,−0.63)
Acute hepatitis E Republic of South Africa 69,537.79(53258.05,90586.17) 394.61(302.23,514.06) 86,552.52(66476.75,113070.04) 434.54(333.75,567.68) 0.48(0.40,0.56) 116.13(74.14,170.13) 0.66(0.42,0.97) 128.55(79.24,200.01) 0.65(0.40,1.00) −0.03(−0.18,0.12)
Acute hepatitis E Republic of South Sudan 18,441.27(13984.55,23783.89) 561.20(425.57,723.78) 30,381.35(23361.24,38571.39) 553.66(425.73,702.92) 0.01(−0.02,0.03) 241.75(43.44,943.30) 7.36(1.32,28.71) 332.51(91.41,899.43) 6.06(1.67,16.39) −0.09(−0.31,0.14)
Acute hepatitis E Republic of Sudan 25,224.38(18356.69,32686.03) 228.36(166.18,295.90) 46,978.28(34470.49,62380.36) 219.78(161.26,291.84) −0.05(−0.09,−0.00) 2221.72(447.68,6752.04) 20.11(4.05,61.13) 855.11(294.17,2457.72) 4.00(1.38,11.50) −5.13(−5.40,−4.87)
Acute hepatitis E Republic of Suriname 685.25(522.89,897.20) 400.75(305.80,524.71) 736.64(548.60,955.60) 388.00(288.96,503.33) −0.12(−0.14,−0.10) 1.65(0.93,2.61) 0.96(0.54,1.52) 1.40(0.80,2.21) 0.74(0.42,1.17) −0.92(−1.11,−0.74)
Acute hepatitis E Republic of Tajikistan 11,976.49(9020.05,15264.59) 416.65(313.80,531.04) 18,238.58(13376.88,24078.21) 409.38(300.26,540.46) −0.14(−0.18,−0.10) 18.64(9.07,32.78) 0.65(0.32,1.14) 21.44(10.94,37.86) 0.48(0.25,0.85) −0.79(−0.91,−0.67)
Acute hepatitis E Republic of the Congo 7152.74(5515.14,9215.65) 539.14(415.71,694.64) 13,108.46(10038.51,17113.24) 527.11(403.66,688.15) −0.04(−0.06,−0.03) 88.05(15.90,328.39) 6.64(1.20,24.75) 35.46(15.86,78.98) 1.43(0.64,3.18) −5.00(−5.47,−4.54)
Acute hepatitis E Republic of the Gambia 2211.92(1681.63,2885.25) 393.73(299.33,513.58) 4922.85(3782.61,6406.28) 388.66(298.64,505.78) −0.04(−0.06,−0.02) 10.94(4.60,20.46) 1.95(0.82,3.64) 9.08(4.08,17.22) 0.72(0.32,1.36) −3.32(−3.70,−2.94)
Acute hepatitis E Republic of the Marshall Islands 112.44(85.75,147.48) 419.85(320.19,550.66) 88.46(66.81,116.98) 383.39(289.56,507.02) −0.23(−0.26,−0.20) 0.25(0.14,0.42) 0.93(0.53,1.57) 0.17(0.10,0.30) 0.75(0.44,1.28) −0.95(−1.09,−0.82)
Acute hepatitis E Republic of the Niger 19,252.43(14611.85,25014.96) 396.83(301.18,515.60) 61,827.74(46366.51,80649.83) 396.67(297.47,517.43) 0.01(−0.02,0.05) 624.15(114.23,1626.52) 12.86(2.35,33.53) 290.00(123.85,632.47) 1.86(0.79,4.06) −6.28(−6.54,−6.03)
Acute hepatitis E Republic of the Philippines 127,108.83(97084.17,163546.78) 396.56(302.89,510.24) 172,539.03(131548.02,223637.71) 385.32(293.78,499.44) −0.12(−0.14,−0.10) 1271.09(503.21,1996.47) 3.97(1.57,6.23) 289.56(187.27,426.75) 0.65(0.42,0.95) −6.77(−7.47,−6.06)
Acute hepatitis E Republic of the Union of Myanmar 63,381.33(48336.21,83347.30) 331.64(252.92,436.12) 67,192.64(51500.24,88178.49) 323.54(247.98,424.59) −0.09(−0.11,−0.07) 335.19(127.76,938.49) 1.75(0.67,4.91) 275.22(137.49,559.60) 1.33(0.66,2.69) −1.27(−1.42,−1.12)
Acute hepatitis E Republic of Trinidad and Tobago 2085.83(1548.82,2812.94) 401.53(298.15,541.50) 1389.40(1052.90,1845.84) 381.72(289.27,507.12) −0.19(−0.23,−0.15) 2.96(1.59,4.95) 0.57(0.31,0.95) 1.88(0.96,3.43) 0.52(0.26,0.94) −0.55(−0.69,−0.40)
Acute hepatitis E Republic of Tunisia 6287.05(4746.61,8241.75) 157.57(118.96,206.56) 5378.24(4161.22,6959.62) 150.00(116.06,194.10) −0.10(−0.20,−0.00) 116.38(49.06,252.35) 2.92(1.23,6.32) 19.19(8.11,37.10) 0.54(0.23,1.03) −4.97(−5.47,−4.47)
Acute hepatitis E Republic of Turkey 39,390.33(31549.94,47419.50) 147.63(118.25,177.72) 50,833.26(37854.51,68510.98) 205.70(153.18,277.24) 1.04(0.58,1.51) 1344.48(331.92,3278.10) 5.04(1.24,12.29) 137.88(85.22,200.42) 0.56(0.34,0.81) −8.00(−8.74,−7.25)
Acute hepatitis E Republic of Uganda 56,630.65(43345.18,72893.02) 549.93(420.92,707.85) 135,085.25(103397.79,173943.56) 541.56(414.53,697.35) −0.04(−0.07,−0.02) 1012.24(131.18,3460.72) 9.83(1.27,33.61) 1025.94(299.16,2970.83) 4.11(1.20,11.91) −3.03(−3.20,−2.86)
Acute hepatitis E Republic of Uzbekistan 40,545.78(30697.40,52201.92) 379.79(287.54,488.97) 46,169.73(35213.85,59973.78) 366.13(279.25,475.60) −0.20(−0.27,−0.13) 92.25(62.95,134.34) 0.86(0.59,1.26) 52.80(29.47,88.89) 0.42(0.23,0.70) −1.88(−2.20,−1.57)
Acute hepatitis E Republic of Vanuatu 351.91(273.65,456.70) 421.71(327.92,547.29) 606.51(456.16,779.65) 411.36(309.39,528.80) −0.09(−0.11,−0.07) 1.33(0.61,2.49) 1.60(0.73,2.99) 1.19(0.64,2.07) 0.80(0.43,1.40) −2.47(−2.61,−2.33)
Acute hepatitis E Republic of Yemen 9386.49(7315.07,11435.86) 111.64(87.00,136.01) 23,217.23(17441.84,29781.57) 132.88(99.83,170.45) 0.72(0.45,1.00) 1710.44(256.67,5828.06) 20.34(3.05,69.31) 490.36(151.01,1299.17) 2.81(0.86,7.44) −7.12(−7.51,−6.72)
Acute hepatitis E Republic of Zambia 23,095.45(17688.77,30374.58) 491.34(376.32,646.20) 51,186.11(39916.79,67254.46) 489.62(381.82,643.32) −0.01(−0.03,0.01) 233.15(56.21,664.86) 4.96(1.20,14.14) 197.96(87.56,410.13) 1.89(0.84,3.92) −3.16(−3.53,−2.78)
Acute hepatitis E Republic of Zimbabwe 23,060.55(17506.94,30456.78) 382.92(290.70,505.73) 31,056.99(23715.47,40534.26) 388.98(297.03,507.68) 0.07(0.05,0.08) 538.48(137.93,1141.75) 8.94(2.29,18.96) 521.62(206.73,926.12) 6.53(2.59,11.60) −0.51(−0.88,−0.14)
Acute hepatitis E Romania 32,780.55(24990.64,42611.45) 436.91(333.08,567.94) 16,648.69(12663.40,22326.99) 412.01(313.38,552.53) −0.17(−0.21,−0.12) 41.04(18.83,73.55) 0.55(0.25,0.98) 20.83(10.25,39.72) 0.52(0.25,0.98) −0.40(−0.54,−0.26)
Acute hepatitis E Russian Federation 61,893.72(47079.58,78651.53) 136.98(104.19,174.07) 46,690.94(35315.34,60478.70) 138.18(104.52,178.99) 0.32(0.17,0.48) 73.95(46.59,115.28) 0.16(0.10,0.26) 58.14(37.13,91.86) 0.17(0.11,0.27) 0.15(0.09,0.21)
Acute hepatitis E Saint Kitts and Nevis 72.34(53.84,97.79) 393.76(293.05,532.33) 52.78(40.18,69.73) 375.35(285.72,495.88) −0.15(−0.17,−0.13) 0.18(0.12,0.28) 0.99(0.63,1.53) 0.13(0.08,0.19) 0.92(0.55,1.38) −0.40(−0.70,−0.09)
Acute hepatitis E Saint Lucia 268.46(203.63,360.61) 402.03(304.94,540.03) 159.76(119.80,216.61) 380.75(285.52,516.25) −0.22(−0.23,−0.21) 0.49(0.29,0.74) 0.73(0.43,1.11) 0.29(0.17,0.46) 0.69(0.40,1.10) −0.17(−0.34,0.00)
Acute hepatitis E Saint Vincent and the Grenadines 220.65(166.14,294.19) 410.49(309.08,547.31) 131.97(98.91,177.54) 391.56(293.46,526.76) −0.15(−0.17,−0.13) 0.36(0.21,0.60) 0.68(0.39,1.11) 0.22(0.12,0.38) 0.65(0.35,1.13) −0.25(−0.46,−0.03)
Acute hepatitis E Slovak Republic 7270.29(5492.20,9609.31) 414.21(312.91,547.47) 4527.39(3436.57,5901.87) 403.83(306.54,526.44) −0.04(−0.11,0.03) 10.79(5.75,18.81) 0.61(0.33,1.07) 5.66(2.80,10.30) 0.50(0.25,0.92) −0.61(−0.67,−0.55)
Acute hepatitis E Socialist Republic of Viet Nam 111,430.59(84962.58,146821.73) 330.98(252.36,436.10) 101,255.20(74956.75,134357.68) 320.24(237.06,424.93) −0.16(−0.24,−0.08) 470.74(238.74,773.36) 1.40(0.71,2.30) 176.81(105.29,275.19) 0.56(0.33,0.87) −3.11(−3.21,−3.01)
Acute hepatitis E Solomon Islands 806.92(608.91,1048.10) 414.62(312.88,538.55) 1329.06(998.15,1740.57) 401.84(301.79,526.26) −0.07(−0.10,−0.05) 6.02(1.92,14.79) 3.09(0.99,7.60) 3.63(1.54,6.91) 1.10(0.47,2.09) −3.38(−3.48,−3.27)
Acute hepatitis E State of Eritrea 11,214.84(8528.90,14234.31) 570.21(433.65,723.73) 17,724.60(13547.54,22974.77) 551.03(421.17,714.25) −0.08(−0.10,−0.06) 113.54(25.39,318.30) 5.77(1.29,16.18) 138.80(42.45,372.31) 4.32(1.32,11.57) −0.83(−0.95,−0.70)
Acute hepatitis E State of Israel 1622.57(1248.80,2074.48) 80.87(62.24,103.40) 2939.12(2289.40,3833.06) 87.13(67.87,113.63) 0.28(0.23,0.33) 2.28(1.48,3.35) 0.11(0.07,0.17) 6.91(4.77,9.93) 0.20(0.14,0.29) 3.14(2.66,3.62)
Acute hepatitis E State of Kuwait 1280.84(969.08,1652.70) 186.72(141.27,240.93) 1950.95(1448.82,2628.34) 178.09(132.26,239.93) −0.15(−0.18,−0.12) 2.95(2.09,4.13) 0.43(0.30,0.60) 2.56(1.58,4.15) 0.23(0.14,0.38) −2.79(−3.23,−2.35)
Acute hepatitis E State of Libya 4421.54(3283.95,5739.32) 191.55(142.27,248.64) 3709.32(2756.25,4986.33) 177.69(132.03,238.86) −0.24(−0.27,−0.21) 54.32(22.11,124.56) 2.35(0.96,5.40) 16.34(9.24,30.73) 0.78(0.44,1.47) −3.25(−3.74,−2.77)
Acute hepatitis E State of Qatar 289.36(215.32,380.65) 189.03(140.66,248.66) 1101.95(803.31,1437.05) 184.55(134.54,240.67) −0.06(−0.08,−0.03) 3.48(1.46,6.03) 2.28(0.95,3.94) 3.16(1.82,4.95) 0.53(0.30,0.83) −4.97(−5.38,−4.56)
Acute hepatitis E Sultanate of Oman 2012.85(1479.95,2652.32) 200.82(147.66,264.62) 2776.70(2076.69,3621.01) 186.13(139.20,242.72) −0.24(−0.30,−0.17) 6.44(3.02,16.19) 0.64(0.30,1.61) 7.62(3.96,13.08) 0.51(0.27,0.88) 0.27(−0.19,0.72)
Acute hepatitis E Swiss Confederation 1927.53(1475.63,2493.99) 122.21(93.56,158.13) 2161.05(1678.17,2769.76) 122.61(95.21,157.14) 0.03(−0.02,0.08) 2.84(1.85,4.14) 0.18(0.12,0.26) 5.92(4.30,7.86) 0.34(0.24,0.45) 1.73(0.92,2.55)
Acute hepatitis E Syrian Arab Republic 14,275.57(10447.04,18646.82) 194.17(142.10,253.63) 9354.81(6999.16,12926.16) 171.96(128.66,237.61) −0.34(−0.41,−0.28) 104.80(46.19,250.46) 1.43(0.63,3.41) 24.65(15.04,39.19) 0.45(0.28,0.72) −3.66(−4.09,−3.22)
Acute hepatitis E Taiwan (Province of China) 20,551.10(15177.44,26382.96) 281.18(207.66,360.97) 12,818.86(9863.22,16479.05) 316.87(243.81,407.35) 0.50(0.44,0.56) 24.89(14.54,41.03) 0.34(0.20,0.56) 14.78(8.67,24.46) 0.37(0.21,0.60) 0.46(0.31,0.61)
Acute hepatitis E Togolese Republic 8107.14(6205.90,10591.49) 376.60(288.28,492.00) 15,590.65(11976.98,20664.73) 373.39(286.85,494.92) −0.07(−0.08,−0.05) 33.86(15.08,60.06) 1.57(0.70,2.79) 30.28(15.14,52.67) 0.73(0.36,1.26) −2.44(−2.57,−2.30)
Acute hepatitis E Tokelau 3.06(2.30,3.98) 403.14(302.84,525.20) 1.92(1.45,2.61) 375.83(283.43,510.05) −0.27(−0.29,−0.24) 0.01(0.01,0.02) 1.28(0.67,2.19) 0.01(0.00,0.03) 2.33(0.95,5.90) −0.71(−1.72,0.31)
Acute hepatitis E Turkmenistan 7154.18(5483.97,9240.75) 379.49(290.89,490.16) 7119.83(5403.81,9395.73) 363.15(275.63,479.24) −0.23(−0.25,−0.21) 163.88(83.97,310.64) 8.69(4.45,16.48) 23.03(15.01,34.44) 1.17(0.77,1.76) −5.60(−6.36,−4.83)
Acute hepatitis E Tuvalu 17.63(13.52,22.43) 412.47(316.51,524.89) 18.59(14.33,24.20) 378.38(291.71,492.65) −0.27(−0.30,−0.25) 0.06(0.03,0.10) 1.39(0.74,2.28) 0.04(0.02,0.06) 0.74(0.43,1.22) −2.07(−2.14,−2.00)
Acute hepatitis E Ukraine 39,202.92(29430.95,51402.73) 260.46(195.53,341.51) 21,577.08(16335.26,28469.68) 255.49(193.43,337.11) 0.12(−0.01,0.25) 142.11(103.29,194.08) 0.94(0.69,1.29) 32.80(21.14,51.14) 0.39(0.25,0.61) −2.80(−3.24,−2.36)
Acute hepatitis E Union of the Comoros 1491.86(1145.11,1933.58) 564.42(433.23,731.54) 1707.84(1298.99,2256.41) 543.99(413.76,718.72) −0.13(−0.14,−0.12) 12.04(3.11,30.33) 4.55(1.18,11.47) 9.73(3.74,23.55) 3.10(1.19,7.50) −1.42(−1.62,−1.22)
Acute hepatitis E United Arab Emirates 1361.62(1018.16,1796.13) 192.59(144.01,254.04) 3102.20(2288.28,4138.77) 183.01(135.00,244.16) −0.08(−0.13,−0.02) 11.98(6.42,21.52) 1.69(0.91,3.04) 11.17(7.18,17.50) 0.66(0.42,1.03) −1.83(−2.22,−1.44)
Acute hepatitis E United Kingdom of Great Britain and Northern Ireland 18,075.81(14022.91,22749.77) 121.85(94.53,153.36) 18,885.53(14575.29,24167.68) 120.64(93.10,154.38) −0.03(−0.08,0.01) 20.91(13.14,32.57) 0.14(0.09,0.22) 32.43(23.64,46.17) 0.21(0.15,0.29) 2.24(1.80,2.69)
Acute hepatitis E United Mexican States 120,768.35(92963.50,154582.60) 278.48(214.36,356.45) 119,930.46(91545.48,157113.21) 277.93(212.15,364.10) 0.16(0.09,0.23) 1613.55(1365.99,1922.63) 3.72(3.15,4.43) 385.83(270.86,529.41) 0.89(0.63,1.23) −4.87(−5.43,−4.30)
Acute hepatitis E United Republic of Tanzania 75,701.96(59980.58,97792.31) 507.28(401.93,655.30) 151,935.14(117853.03,196115.66) 492.36(381.92,635.54) 0.02(−0.02,0.06) 1326.09(235.25,4271.92) 8.89(1.58,28.63) 1079.49(373.53,2822.01) 3.50(1.21,9.15) −2.69(−2.86,−2.51)
Acute hepatitis E United States of America 122,503.23(93417.75,154858.90) 165.44(126.16,209.14) 133,619.49(102746.89,170872.75) 164.33(126.36,210.14) −0.03(−0.06,−0.01) 203.19(150.01,288.23) 0.27(0.20,0.39) 230.83(164.83,335.46) 0.28(0.20,0.41) 0.15(−0.10,0.41)
Acute hepatitis E United States Virgin Islands 161.70(122.27,213.51) 387.64(293.10,511.84) 68.62(51.02,93.04) 376.63(280.03,510.68) −0.10(−0.12,−0.09) 0.28(0.15,0.48) 0.67(0.37,1.15) 0.10(0.05,0.17) 0.54(0.27,0.96) −0.73(−0.84,−0.61)
Measles American Samoa 951.33(341.39,2117.33) 3976.02(1426.82,8849.27) 207.82(62.90,472.58) 1086.42(328.83,2470.53) −2.65(−3.07,−2.22) 536.93(196.79,1065.81) 128.47(47.09,255.01) 210.87(72.93,462.01) 40.34(13.95,88.38) −3.11(−3.20,−3.02)
Measles Antigua and Barbuda 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −99.72(NaN,NaN) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.01) 0.00(0.00,0.00) −58.15(−99.10,1837.29)
Measles Arab Republic of Egypt 1,347,754.90(473919.29,2972814.88) 4826.73(1697.25,10646.57) 7740.00(4179.68,11627.76) 16.63(8.98,24.98) −14.50(−17.38,−11.52) 1775.72(595.93,3702.80) 495,828.88(166398.84,1033923.71) 1.88(0.35,5.06) 874.44(161.21,2356.70) −17.08(−19.70,−14.38)
Measles Argentine Republic 1939.05(1857.04,2027.14) 14.89(14.26,15.56) 0.00(0.00,0.00) 0.00(0.00,0.00) −20.39(−28.41,−11.48) 13.74(9.18,17.75) 1789.71(1195.93,2312.55) 0.00(0.00,0.00) 0.00(0.00,0.00) −30.77(−36.41,−24.63)
Measles Australia 855.79(802.77,912.87) 16.55(15.52,17.65) 2.26(1.63,3.55) 0.04(0.03,0.06) −11.72(−16.13,−7.09) 2.90(2.09,3.64) 150.17(107.93,188.13) 0.00(0.00,0.00) 0.03(0.01,0.17) −9.52(−16.38,−2.11)
Measles Barbados 49.26(36.50,63.90) 58.02(42.99,75.26) 0.00(0.00,0.00) 0.00(0.00,0.00) −96.05(NaN,NaN) 0.15(0.10,0.22) 0.13(0.08,0.19) 0.02(0.00,0.06) 0.02(0.00,0.04) −2.16(−61.38,147.88)
Measles Belize 25.39(16.44,34.94) 24.75(16.03,34.07) 0.00(0.00,0.00) 0.00(0.00,0.00) −27.34(−59.95,31.80) 5.46(3.40,8.27) 5.60(3.49,8.48) 0.00(0.00,0.00) 0.00(0.00,0.00) −26.13(−34.96,−16.10)
Measles Bermuda 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) NA(NA,NA) 0.35(0.15,0.58) 0.06(0.02,0.09) 0.00(0.00,0.00) 0.00(0.00,0.00) −12.68(−22.49,−1.63)
Measles Bolivarian Republic of Venezuela 9718.19(9529.02,9929.69) 107.07(104.99,109.41) 0.00(0.00,0.00) 0.00(0.00,0.00) −8.83(−22.75,7.59) 50.62(37.29,65.59) 4594.25(3384.36,5953.43) 0.00(0.00,0.00) 0.00(0.00,0.01) −25.50(−36.01,−13.26)
Measles Bosnia and Herzegovina 491.87(449.74,535.88) 33.19(30.35,36.17) 2.06(0.00,5.23) 0.31(0.00,0.79) −5.23(−12.60,2.75) 8.18(5.34,12.27) 121.16(79.15,181.82) 0.55(0.09,1.40) 3.66(0.63,9.31) −5.82(−12.69,1.59)
Measles Brunei Darussalam 11.75(5.38,18.66) 10.22(4.67,16.22) 0.00(0.00,0.00) 0.00(0.00,0.00) −13.92(−16.25,−11.52) 1.16(0.54,2.01) 1.33(0.62,2.31) 0.00(0.00,0.00) 0.00(0.00,0.01) −19.73(−22.86,−16.48)
Measles Burkina Faso 296,454.58(104291.10,653522.54) 5240.29(1843.50,11552.01) 58,096.70(36756.21,82516.70) 453.67(287.03,644.37) −8.76(−10.93,−6.53) 16,990.66(5807.12,33506.27) 961,198.58(328521.72,1895523.24) 748.78(323.05,1359.78) 95,886.80(41369.68,174130.86) −10.40(−12.47,−8.29)
Measles Canada 1003.16(943.67,1063.27) 13.09(12.31,13.87) 0.37(0.23,0.49) 0.00(0.00,0.01) −13.08(−19.28,−6.39) 0.04(0.03,0.05) 2.91(2.07,3.96) 0.01(0.00,0.04) 0.76(0.03,3.14) −0.15(−6.14,6.22)
Measles Central African Republic 98,006.64(33989.32,210985.68) 6546.25(2270.28,14092.56) 243.36(122.49,396.13) 8.41(4.23,13.69) −10.44(−14.39,−6.30) 10,146.41(3278.97,20691.83) 151,906.21(49090.77,309786.21) 7.83(2.06,17.44) 226.47(59.70,504.57) −10.32(−13.55,−6.97)
Measles Commonwealth of Dominica 13.40(7.21,20.61) 40.87(22.01,62.89) 0.00(0.00,0.00) 0.00(0.00,0.00) −25.06(−36.36,−11.74) 10.35(4.47,18.75) 3.39(1.46,6.14) 0.02(0.00,0.11) 0.00(0.00,0.02) −13.17(−29.90,7.55)
Measles Commonwealth of the Bahamas 71.32(55.57,88.32) 66.25(51.62,82.04) 0.00(0.00,0.00) 0.00(0.00,0.00) −30.60(−80.42,146.01) 0.17(0.11,0.24) 0.18(0.12,0.26) 0.00(0.00,0.00) 0.00(0.00,0.00) −18.04(−38.43,9.10)
Measles Cook Islands 174.97(60.21,378.56) 2032.06(699.22,4396.57) 4.07(1.28,9.35) 78.44(24.78,180.43) −8.75(−12.13,−5.24) 429.20(151.92,886.93) 36.96(13.08,76.37) 9.56(3.00,23.45) 0.50(0.16,1.22) −11.83(−14.91,−8.64)
Measles Czech Republic 2364.76(2273.62,2457.33) 77.69(74.69,80.73) 1.76(0.29,6.81) 0.08(0.01,0.31) −1.78(−8.99,6.01) 0.20(0.14,0.29) 6.21(4.23,8.85) 0.00(0.00,0.00) 0.00(0.00,0.02) −4.38(−10.36,1.99)
Measles Democratic People’s Republic of Korea 0.00(0.00,0.00) 0.00(0.00,0.00) 0.90(0.00,2.74) 0.01(0.00,0.04) −31.50(−58.22,12.29) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.01) −45.38(−60.85,−23.78)
Measles Democratic Republic of Sao Tome and Principe 3262.49(1141.07,7263.41) 4668.44(1632.81,10393.52) 189.25(112.15,292.09) 185.90(110.16,286.92) −10.07(−12.74,−7.32) 8336.31(3131.31,16312.99) 5825.75(2188.29,11400.18) 99.15(38.71,191.33) 100.93(39.41,194.78) −13.36(−16.00,−10.64)
Measles Democratic Republic of the Congo 1,362,940.30(472173.21,2958124.36) 6295.28(2180.92,13663.28) 92,032.27(57255.65,131424.11) 192.11(119.51,274.33) −8.87(−10.37,−7.35) 6048.59(1859.69,13068.67) 1,309,530.68(402626.43,2829389.71) 75.32(15.79,151.64) 36,082.04(7562.79,72645.71) −10.22(−11.93,−8.47)
Measles Democratic Republic of Timor−Leste 107.41(88.98,126.15) 26.41(21.88,31.02) 4.05(1.01,8.12) 0.59(0.15,1.18) −8.85(−12.87,−4.63) 32.95(19.09,54.15) 133.98(77.62,220.19) 0.37(0.07,0.89) 2.56(0.51,6.10) −14.12(−19.28,−8.63)
Measles Democratic Socialist Republic of Sri Lanka 3860.43(3741.10,3974.41) 53.32(51.67,54.89) 0.00(0.00,0.00) 0.00(0.00,0.00) −13.37(−20.38,−5.75) 16.34(11.23,22.58) 1183.01(813.10,1634.61) 0.01(0.00,0.02) 0.48(0.01,1.66) −15.84(−22.09,−9.10)
Measles Dominican Republic 3285.09(3170.59,3384.86) 93.80(90.53,96.65) 0.00(0.00,0.00) 0.00(0.00,0.00) −30.43(−50.37,−2.49) 56.74(37.19,79.97) 1987.08(1302.52,2800.61) 0.00(0.00,0.00) 0.00(0.00,0.00) −32.96(−52.18,−6.03)
Measles Eastern Republic of Uruguay 108.32(88.54,129.40) 10.06(8.22,12.01) 2.42(0.45,6.08) 0.27(0.05,0.67) −9.08(−18.66,1.63) 0.04(0.03,0.05) 0.42(0.29,0.55) 0.03(0.01,0.06) 0.23(0.05,0.52) −0.10(−7.36,7.74)
Measles Federal Democratic Republic of Ethiopia 1,946,649.58(665891.11,4183505.48) 6606.15(2259.77,14197.14) 131,893.27(85837.98,189162.19) 230.59(150.07,330.71) −9.38(−11.00,−7.73) 18,064.84(6312.69,35106.18) 5,323,208.50(1860176.27,10344819.74) 217.74(111.91,383.18) 124,542.02(64010.84,219173.95) −12.46(−13.99,−10.91)
Measles Federal Democratic Republic of Nepal 622,093.98(215892.46,1349761.01) 6011.26(2086.16,13042.66) 38,897.55(21652.32,57423.50) 312.32(173.85,461.07) −10.22(−12.76,−7.61) 6531.87(2168.22,13168.39) 675,971.02(224385.40,1362772.19) 97.11(31.60,184.93) 12,094.77(3935.18,23031.58) −13.28(−15.53,−10.97)
Measles Federal Republic of Germany 163.58(139.97,189.57) 0.94(0.81,1.09) 6.80(2.87,12.00) 0.04(0.02,0.08) −4.20(−9.11,0.98) 0.76(0.51,1.06) 131.36(88.19,183.06) 0.01(0.00,0.03) 1.58(0.04,4.16) −7.12(−10.48,−3.64)
Measles Federal Republic of Nigeria 3,046,528.79(1053307.74,6601308.77) 6279.04(2170.92,13605.62) 806,766.62(547008.10,1081789.78) 631.41(428.11,846.65) −7.60(−9.20,−5.97) 10,632.61(3797.40,21726.53) 5,158,833.12(1842461.10,10541491.97) 404.44(197.72,701.34) 516,761.10(252632.03,896117.64) −10.52(−12.07,−8.94)
Measles Federal Republic of Somalia 381,452.35(132760.57,788412.41) 8060.54(2805.39,16660.10) 422,926.46(189386.03,763921.19) 3308.14(1481.38,5975.42) −3.17(−4.02,−2.30) 24,725.93(8848.32,44472.75) 1,170,114.99(418732.80,2104601.72) 10,280.49(3678.20,21140.97) 1,314,299.22(470235.69,2702746.40) −3.03(−3.53,−2.53)
Measles Federated States of Micronesia 2182.52(766.83,4803.45) 3795.84(1333.67,8354.15) 340.85(106.63,771.57) 822.43(257.29,1861.71) −16.64(−22.36,−10.51) 1201.41(432.92,2521.92) 690.79(248.92,1450.05) 208.10(69.96,456.12) 86.24(28.99,189.04) −18.03(−23.70,−11.95)
Measles Federative Republic of Brazil 58,682.64(58215.15,59126.74) 87.33(86.64,88.00) 695.34(641.40,748.54) 1.09(1.00,1.17) −2.32(−15.48,12.90) 36.35(28.53,43.72) 24,427.27(19172.82,29377.20) 0.05(0.02,0.11) 33.67(12.58,69.32) −12.18(−23.12,0.30)
Measles French Republic 121,492.95(120809.73,122186.08) 752.66(748.42,756.95) 15.51(8.70,23.19) 0.10(0.06,0.15) −20.51(−26.03,−14.57) 4.26(3.37,5.35) 688.15(544.34,863.46) 0.00(0.00,0.00) 0.04(0.02,0.07) −19.98(−24.84,−14.81)
Measles Gabonese Republic 23,563.82(8239.43,52227.00) 4636.89(1621.36,10277.24) 953.46(397.05,1644.82) 115.28(48.01,198.88) −6.26(−8.84,−3.62) 1849.44(608.95,3904.71) 9398.49(3094.56,19843.00) 22.01(3.31,65.49) 182.00(27.42,541.65) −8.94(−11.20,−6.63)
Measles Georgia 1056.42(995.09,1118.17) 58.79(55.38,62.23) 4.83(0.98,9.77) 0.52(0.11,1.05) −0.72(−7.76,6.87) 0.15(0.11,0.21) 2.74(1.92,3.82) 0.00(0.00,0.00) 0.02(0.01,0.03) 2.07(−5.39,10.12)
Measles Grand Duchy of Luxembourg 15.78(8.73,24.24) 17.89(9.89,27.48) 0.06(0.02,0.10) 0.04(0.02,0.07) −4.30(−10.30,2.12) 0.08(0.04,0.12) 0.07(0.03,0.10) 0.00(0.00,0.00) 0.00(0.00,0.00) −10.60(−15.95,−4.91)
Measles Greenland 468.97(161.71,1014.85) 2621.14(903.83,5672.14) 0.56(0.19,1.24) 3.66(1.22,8.10) −6.64(−9.95,−3.20) 260.53(88.44,591.79) 46.61(15.82,105.88) 2.76(0.85,6.95) 0.42(0.13,1.07) −6.85(−8.75,−4.90)
Measles Grenada 6.52(2.23,12.24) 15.47(5.28,29.03) 0.00(0.00,0.00) 0.00(0.00,0.00) −6.76(−92.03,990.45) 0.11(0.06,0.17) 0.04(0.02,0.07) 0.00(0.00,0.00) 0.00(0.00,0.00) −15.38(−22.30,−7.84)
Measles Guam 1446.52(519.10,3424.00) 2671.58(958.72,6323.79) 524.37(147.68,1261.03) 1081.50(304.59,2600.86) −1.97(−2.47,−1.46) 273.23(96.16,579.83) 147.94(52.06,313.95) 72.53(11.40,195.33) 35.17(5.53,94.71) −3.08(−3.72,−2.45)
Measles Hashemite Kingdom of Jordan 277.79(244.95,309.57) 13.25(11.68,14.77) 1.78(0.00,4.32) 0.04(0.00,0.09) −18.92(−25.27,−12.02) 3.53(2.37,5.09) 74.06(49.76,106.74) 0.00(0.00,0.00) 0.00(0.00,0.01) −24.85(−31.30,−17.79)
Measles Hellenic Republic 238.15(209.75,268.93) 8.47(7.46,9.57) 9.47(5.90,11.43) 0.50(0.31,0.60) −11.48(−19.45,−2.73) 0.03(0.02,0.04) 0.73(0.52,1.00) 0.00(0.00,0.01) 0.04(0.02,0.12) −2.38(−9.15,4.89)
Measles Hungary 28.44(17.65,39.22) 0.98(0.61,1.35) 0.09(0.01,0.33) 0.00(0.00,0.02) −4.68(−11.08,2.18) 0.05(0.03,0.07) 1.41(0.90,1.96) 0.08(0.02,0.18) 1.45(0.47,3.38) −2.16(−8.98,5.17)
Measles Independent State of Papua New Guinea 92,717.80(32609.13,204239.29) 4355.72(1531.92,9594.81) 7468.88(6928.51,11490.46) 152.46(141.43,234.54) −4.45(−6.98,−1.84) 4165.73(1464.94,8513.45) 88,673.51(31183.29,181220.96) 94.20(9.70,248.24) 4614.90(475.45,12161.31) −5.62(−7.98,−3.20)
Measles Independent State of Samoa 4924.81(1729.97,10640.34) 5376.75(1888.72,11616.79) 19.93(5.37,50.94) 19.75(5.32,50.46) −7.32(−11.06,−3.42) 1262.39(467.09,2538.33) 1156.28(427.83,2324.97) 4.94(1.27,13.83) 4.99(1.28,13.96) −4.22(−7.91,−0.39)
Measles Ireland 546.27(503.07,591.05) 41.11(37.86,44.48) 3.79(0.00,8.11) 0.29(0.00,0.61) −10.99(−14.52,−7.31) 0.19(0.14,0.24) 2.47(1.85,3.20) 0.00(0.00,0.00) 0.02(0.00,0.05) −9.91(−13.64,−6.03)
Measles Islamic Republic of Afghanistan 379,547.91(130638.35,800871.42) 6810.52(2344.15,14370.66) 258,344.98(204278.81,311199.35) 1453.28(1149.14,1750.60) −7.61(−9.43,−5.75) 14,099.00(5166.86,26251.35) 785,731.61(287946.98,1462977.47) 1867.30(1118.34,3049.45) 331,944.80(198803.53,542093.02) −9.23(−10.77,−7.67)
Measles Islamic Republic of Iran 5046.12(4924.20,5188.26) 16.01(15.63,16.47) 93.57(76.41,111.96) 0.36(0.30,0.43) −14.79(−20.71,−8.44) 8.24(5.47,12.15) 2596.68(1724.00,3828.71) 0.03(0.02,0.06) 8.63(4.44,14.51) −18.25(−23.73,−12.38)
Measles Islamic Republic of Mauritania 68,850.60(23836.49,149850.30) 6071.91(2102.13,13215.23) 12,700.10(8916.55,17922.46) 544.56(382.33,768.49) −6.09(−8.50,−3.62) 6513.75(2422.98,12663.24) 73,860.82(27474.65,143591.12) 290.59(158.74,464.70) 6777.09(3702.08,10837.56) −8.66(−10.84,−6.41)
Measles Islamic Republic of Pakistan 2,973,710.95(1024387.77,6625142.65) 4877.87(1680.33,10867.42) 187,726.66(137022.76,242595.50) 171.87(125.45,222.11) −13.37(−15.81,−10.85) 4698.04(1751.26,8936.29) 2,864,082.92(1067623.49,5447860.87) 57.17(22.85,114.72) 62,438.77(24952.30,125305.68) −14.89(−17.10,−12.61)
Measles Jamaica 3627.56(3511.15,3741.47) 332.04(321.38,342.47) 0.00(0.00,0.00) 0.00(0.00,0.00) −25.57(−43.06,−2.72) 4.04(2.97,5.36) 44.13(32.46,58.58) 0.00(0.00,0.00) 0.00(0.00,0.00) −27.47(−34.71,−19.43)
Measles Japan 3163.44(3061.94,3258.39) 9.48(9.18,9.77) 5.81(1.95,10.64) 0.03(0.01,0.05) −14.54(−19.58,−9.18) 11.49(10.21,12.80) 3834.06(3405.69,4269.66) 0.00(0.00,0.01) 0.99(0.34,1.86) −16.75(−19.38,−14.04)
Measles Kingdom of Bahrain 56.77(42.87,72.82) 28.37(21.42,36.39) 1.23(0.00,3.97) 0.31(0.00,0.98) −5.38(−10.10,−0.41) 5.73(3.68,8.48) 11.47(7.37,16.96) 0.02(0.00,0.08) 0.10(0.00,0.33) −8.86(−13.34,−4.14)
Measles Kingdom of Belgium 46,972.30(46596.89,47356.14) 1900.39(1885.20,1915.92) 15.05(8.44,22.49) 0.59(0.33,0.88) −17.39(−22.29,−12.18) 4.85(3.28,6.92) 119.85(81.05,170.96) 0.00(0.00,0.01) 0.09(0.03,0.18) −13.25(−16.77,−9.58)
Measles Kingdom of Bhutan 171.88(147.41,199.09) 50.46(43.28,58.45) 0.00(0.00,0.00) 0.00(0.00,0.00) −13.58(−20.37,−6.21) 69.33(23.53,123.58) 236.16(80.16,420.94) 0.01(0.00,0.04) 0.03(0.01,0.09) −17.53(−23.52,−11.06)
Measles Kingdom of Cambodia 2366.10(2270.79,2461.56) 41.56(39.88,43.24) 4.92(0.97,9.70) 0.07(0.01,0.15) −15.02(−20.51,−9.16) 49.36(29.15,76.58) 2810.32(1659.89,4359.94) 0.04(0.01,0.08) 2.50(0.45,5.47) −18.26(−23.37,−12.81)
Measles Kingdom of Denmark 173.90(148.18,197.15) 13.91(11.85,15.77) 0.00(0.00,0.00) 0.00(0.00,0.00) −10.53(−14.29,−6.60) 5.80(3.76,8.02) 72.51(47.06,100.26) 0.00(0.00,0.00) 0.00(0.00,0.00) −18.66(−24.65,−12.20)
Measles Kingdom of Eswatini 21,130.55(7433.38,46551.87) 4428.71(1557.95,9756.71) 2234.97(1524.48,4309.28) 417.75(284.95,805.46) −8.45(−10.78,−6.07) 3362.59(1220.82,6837.61) 16,043.81(5824.86,32624.05) 165.89(77.29,341.52) 887.52(413.48,1827.17) −10.21(−12.62,−7.74)
Measles Kingdom of Lesotho 18,464.82(6311.46,39608.24) 2205.23(753.77,4730.36) 734.08(584.45,1165.87) 87.51(69.67,138.99) −8.26(−11.03,−5.40) 2061.14(728.62,4381.40) 17,258.33(6100.88,36686.37) 62.00(22.57,138.62) 520.06(189.34,1162.78) −9.86(−12.48,−7.17)
Measles Kingdom of Morocco 546,014.73(192045.96,1202957.44) 4375.17(1538.85,9639.20) 5923.91(5923.91,5923.91) 45.87(45.87,45.87) −10.21(−12.18,−8.19) 3180.27(1226.38,6337.28) 396,893.01(153049.77,790881.93) 16.36(4.47,44.64) 2112.42(577.22,5764.91) −12.81(−14.65,−10.94)
Measles Kingdom of Norway 91.92(73.34,110.58) 8.26(6.59,9.94) 0.02(0.00,0.03) 0.00(0.00,0.00) −8.68(−13.86,−3.19) 0.03(0.02,0.05) 0.37(0.26,0.50) 0.00(0.00,0.01) 0.04(0.01,0.07) −1.22(−4.72,2.41)
Measles Kingdom of Saudi Arabia 303,700.70(108081.38,665024.66) 3698.52(1316.23,8098.79) 1212.23(267.73,2491.42) 11.96(2.64,24.59) −15.20(−18.87,−11.37) 928.04(307.90,1996.05) 76,205.23(25283.33,163903.59) 0.82(0.19,1.82) 82.67(19.05,184.47) −20.10(−23.66,−16.37)
Measles Kingdom of Spain 20,956.21(20674.43,21208.65) 188.00(185.47,190.26) 1.84(0.00,4.64) 0.02(0.00,0.05) −15.61(−20.67,−10.22) 0.68(0.51,0.90) 76.22(57.14,100.75) 0.00(0.00,0.00) 0.00(0.00,0.01) −18.12(−21.93,−14.13)
Measles Kingdom of Sweden 28.41(19.28,38.68) 1.35(0.91,1.84) 0.15(0.09,0.22) 0.01(0.00,0.01) −5.00(−9.58,−0.20) 0.02(0.01,0.02) 0.38(0.27,0.49) 0.00(0.00,0.00) 0.01(0.00,0.02) −3.65(−7.12,−0.06)
Measles Kingdom of Thailand 836,263.80(292471.21,1856276.72) 3676.39(1285.77,8160.59) 1129.80(809.00,1463.40) 8.28(5.93,10.72) −8.61(−11.38,−5.75) 990.46(377.97,1963.59) 225,299.41(85975.68,446655.50) 2.65(0.46,8.06) 361.64(63.20,1099.62) −10.99(−13.08,−8.85)
Measles Kingdom of the Netherlands 15.49(8.73,23.29) 0.40(0.23,0.61) 0.00(0.00,0.00) 0.00(0.00,0.00) −7.20(−14.68,0.94) 0.00(0.00,0.00) 0.07(0.05,0.10) 0.00(0.00,0.01) 0.16(0.07,0.34) 2.63(−2.80,8.36)
Measles Kingdom of Tonga 2950.76(1039.98,6342.51) 5529.67(1948.91,11885.77) 9.67(2.76,25.12) 19.50(5.58,50.67) −8.76(−11.92,−5.49) 1259.47(493.80,2496.94) 672.08(263.50,1332.42) 4.85(1.32,12.98) 2.41(0.65,6.44) −9.60(−12.42,−6.70)
Measles Kyrgyz Republic 575.22(531.73,623.48) 27.24(25.18,29.53) 3.14(0.00,7.31) 0.11(0.00,0.26) −5.02(−14.83,5.91) 0.14(0.10,0.19) 3.02(2.16,3.91) 2.03(0.87,4.14) 57.20(24.46,116.76) −4.86(−15.96,7.70)
Measles Lao People’s Democratic Republic 150,337.39(51441.35,321112.50) 6627.23(2267.66,14155.40) 1537.81(886.56,2059.39) 51.41(29.64,68.84) −10.70(−12.87,−8.49) 6816.35(2313.68,14087.51) 154,627.71(52485.46,319572.53) 26.81(6.64,60.95) 802.18(198.63,1823.29) −12.99(−15.00,−10.93)
Measles Lebanese Republic 54,366.02(18837.73,121540.12) 4059.79(1406.71,9076.02) 2992.09(1918.32,4888.27) 179.57(115.13,293.37) −6.58(−9.57,−3.50) 951.16(366.70,1815.60) 12,737.26(4910.58,24313.27) 33.91(10.25,76.41) 565.10(170.75,1273.25) −10.28(−12.93,−7.56)
Measles Malaysia 405,051.01(140668.33,897898.24) 4855.00(1686.07,10762.33) 7341.94(5611.02,9230.37) 71.59(54.71,90.01) −8.89(−10.89,−6.84) 868.54(342.02,1609.91) 72,462.37(28534.75,134314.09) 5.22(0.21,16.86) 535.27(21.80,1728.74) −11.57(−13.41,−9.70)
Measles Mongolia 293.58(261.36,327.70) 25.86(23.02,28.87) 0.00(0.00,0.00) 0.00(0.00,0.00) −6.77(−18.69,6.89) 11.05(7.30,15.80) 125.48(82.83,179.35) 47.17(28.65,75.11) 619.22(376.08,985.93) −3.50(−14.77,9.25)
Measles Montenegro 8.70(3.90,14.62) 4.06(1.82,6.81) 0.00(0.00,0.00) 0.00(0.00,0.00) 7.23(2.97,11.66) 0.76(0.28,1.48) 1.62(0.60,3.17) 0.61(0.22,1.24) 0.91(0.32,1.87) 1.91(−1.13,5.06)
Measles New Zealand 6836.79(6686.53,7009.18) 620.91(607.27,636.57) 0.00(0.00,0.00) 0.00(0.00,0.00) −12.06(−18.44,−5.19) 1.91(1.35,2.64) 21.04(14.91,29.04) 0.00(0.00,0.00) 0.00(0.00,0.00) −15.73(−21.70,−9.30)
Measles North Macedonia 1659.21(1584.01,1738.53) 238.07(227.28,249.45) 0.00(0.00,0.00) 0.00(0.00,0.00) −9.43(−17.33,−0.77) 55.92(38.52,78.29) 389.73(268.44,545.61) 2.85(1.23,4.88) 12.72(5.50,21.81) −9.58(−16.85,−1.68)
Measles Northern Mariana Islands 389.32(140.53,906.27) 2400.78(866.58,5588.57) 175.71(50.34,417.18) 1171.63(335.69,2781.81) −1.39(−2.08,−0.70) 180.25(62.54,413.79) 29.23(10.14,67.10) 54.04(12.89,134.98) 8.10(1.93,20.24) −2.94(−3.66,−2.22)
Measles Palestine 46,000.95(16469.71,101932.06) 3854.04(1379.86,8540.05) 395.93(255.60,638.41) 16.44(10.62,26.51) −12.78(−14.64,−10.87) 2058.23(763.00,3935.35) 24,566.55(9106.96,46971.49) 2.88(0.72,8.14) 69.41(17.32,195.89) −15.90(−17.73,−14.04)
Measles People’s Democratic Republic of Algeria 547,644.48(192494.00,1205788.70) 4051.65(1424.13,8920.81) 8760.38(5569.92,14276.69) 53.26(33.86,86.79) −7.28(−10.86,−3.55) 1658.93(606.46,3556.20) 224,230.23(81972.17,480676.56) 9.08(4.05,20.46) 1492.96(665.49,3364.93) −10.53(−13.80,−7.14)
Measles People’s Republic of Bangladesh 3,829,548.68(1323408.52,8203119.25) 6344.59(2192.55,13590.49) 4241.41(1566.97,7484.05) 6.95(2.57,12.27) −12.84(−15.80,−9.77) 3277.72(1046.14,7317.27) 1,978,406.28(631440.10,4416653.29) 7.23(1.02,22.32) 4407.69(619.39,13611.26) −15.33(−17.56,−13.04)
Measles People’s Republic of China 83,583.39(83045.52,84166.68) 18.78(18.66,18.91) 692.45(636.52,745.15) 0.21(0.19,0.22) −9.85(−13.20,−6.36) 5.74(3.78,8.05) 25,541.60(16818.05,35827.67) 0.35(0.21,0.54) 1158.28(701.83,1814.50) −12.19(−14.80,−9.50)
Measles Plurinational State of Bolivia 778.93(726.77,833.40) 23.26(21.70,24.89) 0.00(0.00,0.00) 0.00(0.00,0.00) −21.43(−34.54,−5.68) 16.82(11.21,24.62) 563.36(375.51,824.56) 0.00(0.00,0.00) 0.00(0.00,0.00) −35.01(−45.83,−22.02)
Measles Portuguese Republic 394.24(355.11,433.25) 13.23(11.91,14.53) 0.00(0.00,0.00) 0.00(0.00,0.00) −11.19(−17.15,−4.80) 7.68(5.45,9.89) 229.05(162.57,294.94) 0.00(0.00,0.00) 0.00(0.00,0.00) −28.19(−35.14,−20.49)
Measles Principality of Andorra 10.45(4.81,17.31) 77.64(35.73,128.61) 0.00(0.00,0.00) 0.00(0.00,0.00) −10.20(−16.94,−2.92) 7.56(2.75,14.13) 1.02(0.37,1.90) 0.00(0.00,0.00) 0.00(0.00,0.00) −12.31(−18.85,−5.25)
Measles Principality of Monaco 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.02) 0.07(0.00,0.24) −18.77(−22.14,−15.24) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.04(0.00,0.19) 0.00(0.00,0.01) −18.26(−20.05,−16.43)
Measles Puerto Rico 359.22(325.59,393.60) 26.97(24.44,29.55) 0.00(0.00,0.00) 0.00(0.00,0.00) −18.99(−30.52,−5.54) 0.66(0.45,0.87) 8.83(6.00,11.58) 0.00(0.00,0.01) 0.02(0.01,0.04) −9.67(−19.23,1.03)
Measles Republic of Albania 72,509.03(72067.01,72939.26) 5014.76(4984.19,5044.51) 0.00(0.00,0.00) 0.00(0.00,0.00) −4.49(−14.65,6.87) 1122.78(832.41,1468.40) 16,234.44(12035.93,21231.75) 0.84(0.23,1.90) 5.16(1.40,11.71) −5.21(−14.48,5.08)
Measles Republic of Angola 373,797.19(129617.19,806810.05) 6482.76(2247.95,13992.50) 79,552.06(55146.30,106223.43) 425.97(295.28,568.78) −6.88(−8.36,−5.36) 7516.73(2474.97,16074.08) 433,416.27(142707.24,926834.50) 159.46(42.37,305.97) 29,779.70(7913.32,57142.17) −9.97(−11.44,−8.47)
Measles Republic of Armenia 863.26(806.57,919.70) 65.01(60.74,69.26) 0.00(0.00,0.00) 0.00(0.00,0.00) −12.84(−19.81,−5.25) 0.88(0.57,1.31) 11.72(7.53,17.35) 0.00(0.00,0.00) 0.00(0.00,0.00) −15.18(−21.37,−8.51)
Measles Republic of Austria 106.56(86.83,126.91) 5.69(4.64,6.77) 0.93(0.00,2.75) 0.05(0.00,0.16) −0.96(−6.53,4.94) 0.90(0.57,1.33) 16.88(10.61,24.98) 0.01(0.00,0.01) 0.09(0.01,0.24) −3.87(−9.87,2.53)
Measles Republic of Azerbaijan 1995.87(1906.67,2077.61) 63.76(60.91,66.38) 1.91(0.00,4.85) 0.06(0.00,0.16) −15.56(−21.39,−9.30) 11.08(7.50,15.48) 346.91(234.64,484.45) 0.03(0.01,0.05) 0.83(0.39,1.65) −15.14(−20.54,−9.36)
Measles Republic of Belarus 218.15(192.09,245.99) 6.95(6.12,7.84) 2.50(0.00,5.84) 0.12(0.00,0.29) −14.11(−20.98,−6.65) 0.02(0.02,0.03) 0.72(0.52,0.98) 0.02(0.01,0.05) 0.42(0.10,1.10) −1.17(−6.57,4.54)
Measles Republic of Benin 181,653.53(62952.04,395434.36) 6330.05(2193.68,13779.64) 16,194.86(10379.48,22379.29) 215.46(138.09,297.74) −6.92(−8.92,−4.88) 16,917.82(6329.16,32455.70) 485,490.53(181627.91,931381.15) 255.96(102.97,495.71) 19,238.56(7739.53,37259.19) −9.16(−11.09,−7.19)
Measles Republic of Botswana 29,886.29(10682.22,65920.19) 4036.11(1442.62,8902.45) 430.22(269.48,668.81) 46.92(29.39,72.93) −9.05(−12.02,−5.98) 2462.62(950.00,4941.29) 18,235.02(7034.50,36588.87) 25.38(7.58,66.23) 232.71(69.48,607.33) −10.46(−13.22,−7.61)
Measles Republic of Bulgaria 142.85(118.81,166.41) 6.04(5.03,7.04) 0.00(0.00,0.00) 0.00(0.00,0.00) −5.70(−16.88,6.99) 0.03(0.02,0.04) 0.64(0.49,0.83) 0.03(0.01,0.06) 0.44(0.18,0.81) 4.80(−3.41,13.72)
Measles Republic of Burundi 185,984.49(65037.50,411624.17) 5894.67(2061.33,13046.19) 33,506.18(18896.67,53073.57) 460.60(259.76,729.58) −9.61(−12.42,−6.71) 9396.28(2897.87,20698.49) 296,464.68(91431.63,653063.99) 433.55(143.36,907.86) 31,538.66(10428.81,66042.43) −10.11(−12.76,−7.38)
Measles Republic of Cabo Verde 9522.54(3340.82,20963.97) 4896.63(1717.90,10779.98) 187.18(115.55,284.87) 97.11(59.95,147.80) −15.64(−19.44,−11.67) 6739.28(2975.46,11551.17) 13,105.98(5786.42,22463.72) 47.06(20.20,85.09) 90.71(38.94,164.01) −18.36(−21.77,−14.79)
Measles Republic of Cameroon 363,278.29(126609.53,798294.44) 6118.82(2132.53,13445.94) 76,154.62(52148.89,101390.86) 450.54(308.52,599.85) −6.60(−10.12,−2.95) 12,328.46(4725.38,23283.71) 731,948.83(280548.84,1382369.31) 482.06(192.23,854.27) 81,481.62(32493.04,144394.68) −8.71(−12.06,−5.23)
Measles Republic of Chad 256,550.18(88455.17,545990.70) 7277.44(2509.17,15487.86) 165,579.85(99224.99,248507.48) 1512.20(906.20,2269.56) −5.29(−6.13,−4.43) 18,846.52(6422.23,37424.62) 664,392.97(226401.78,1319323.55) 2749.97(1231.74,4607.32) 301,109.88(134870.62,504481.08) −6.56(−7.36,−5.76)
Measles Republic of Chile 1916.88(1836.94,1995.06) 36.34(34.83,37.82) 0.00(0.00,0.00) 0.00(0.00,0.00) −7.57(−19.29,5.86) 0.11(0.08,0.15) 5.73(4.12,7.70) 0.00(0.00,0.00) 0.00(0.00,0.01) −12.37(−19.37,−4.75)
Measles Republic of Colombia 12,235.54(12013.16,12461.65) 81.28(79.81,82.79) 0.00(0.00,0.00) 0.00(0.00,0.00) −19.73(−29.08,−9.14) 50.02(35.69,64.25) 7529.32(5371.82,9671.68) 0.00(0.00,0.00) 0.00(0.00,0.01) −29.58(−36.31,−22.14)
Measles Republic of Costa Rica 74.90(59.28,91.89) 5.28(4.18,6.48) 0.00(0.00,0.00) 0.00(0.00,0.00) −19.35(−29.84,−7.30) 0.07(0.05,0.10) 1.02(0.69,1.40) 0.00(0.00,0.00) 0.00(0.00,0.00) −29.27(−37.82,−19.53)
Measles Republic of Croatia 115.65(95.05,138.24) 8.72(7.17,10.42) 0.13(0.02,0.51) 0.02(0.00,0.06) −10.17(−16.37,−3.51) 0.03(0.02,0.04) 0.34(0.24,0.47) 0.00(0.00,0.00) 0.00(0.00,0.00) −12.61(−18.22,−6.61)
Measles Republic of Cuba 11.53(5.81,18.41) 0.32(0.16,0.50) 0.00(0.00,0.00) 0.00(0.00,0.00) −8.38(−21.83,7.39) 0.00(0.00,0.00) 0.13(0.09,0.17) 0.00(0.00,0.00) 0.00(0.00,0.01) −8.85(−19.63,3.37)
Measles Republic of Cyprus 3.87(0.97,7.80) 1.49(0.38,3.01) 1.00(0.00,2.83) 0.35(0.00,0.99) −1.44(−7.93,5.51) 0.22(0.04,0.51) 0.57(0.10,1.33) 0.01(0.00,0.04) 0.03(0.00,0.10) −5.94(−12.23,0.80)
Measles Republic of C么te d’Ivoire 414,731.32(143966.20,911214.48) 5994.52(2080.89,13170.69) 88,524.50(66938.65,112392.01) 615.41(465.35,781.33) −9.86(−12.40,−7.25) 8821.82(3151.61,17361.19) 610,337.78(218043.93,1201134.40) 498.89(250.64,887.18) 71,763.94(36053.82,127618.29) −11.17(−13.59,−8.68)
Measles Republic of Djibouti 7463.01(2579.07,16658.06) 3327.64(1149.97,7427.57) 4835.39(2220.46,8784.91) 915.15(420.25,1662.64) −7.99(−9.99,−5.95) 4794.54(1639.91,9525.93) 10,752.89(3677.88,21364.13) 657.98(247.60,1325.49) 3476.60(1308.25,7003.52) −9.57(−11.35,−7.74)
Measles Republic of Ecuador 1619.39(1543.20,1696.51) 32.67(31.13,34.22) 0.00(0.00,0.00) 0.00(0.00,0.00) −20.76(−31.47,−8.37) 222.23(169.35,274.39) 11,017.26(8395.66,13602.81) 0.00(0.00,0.00) 0.00(0.00,0.00) −41.04(−47.01,−34.41)
Measles Republic of El Salvador 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −42.43(−84.81,118.22) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −45.37(−85.57,106.83)
Measles Republic of Equatorial Guinea 14,685.55(5068.42,32110.61) 6119.48(2112.02,13380.52) 1761.92(660.31,3260.17) 228.78(85.74,423.33) −4.01(−5.67,−2.32) 6677.95(2118.69,14875.56) 16,025.77(5084.44,35698.42) 21.69(2.29,60.95) 167.03(17.62,469.39) −11.83(−13.28,−10.34)
Measles Republic of Estonia 32.11(21.44,43.40) 6.99(4.67,9.45) 0.00(0.00,0.00) 0.00(0.00,0.00) −8.94(−13.77,−3.85) 0.02(0.01,0.03) 0.09(0.06,0.14) 0.00(0.00,0.00) 0.00(0.00,0.00) −14.48(−20.68,−7.79)
Measles Republic of Fiji 13,415.53(4715.03,29534.03) 3739.98(1314.46,8233.50) 890.07(253.95,1999.06) 253.85(72.43,570.14) −8.00(−10.33,−5.61) 799.21(282.07,1601.88) 2866.82(1011.82,5746.04) 37.48(8.35,100.22) 131.42(29.26,351.39) −9.23(−11.47,−6.93)
Measles Republic of Finland 2.83(0.00,5.81) 0.22(0.00,0.46) 2.84(0.00,6.68) 0.25(0.00,0.58) 3.39(−0.68,7.63) 0.00(0.00,0.01) 0.05(0.03,0.07) 0.01(0.00,0.03) 0.11(0.00,0.37) 4.95(−0.40,10.60)
Measles Republic of Ghana 461,805.93(161350.70,1020043.63) 5591.14(1953.49,12349.80) 4022.73(2154.48,5979.81) 24.66(13.21,36.65) −11.63(−14.24,−8.94) 8374.99(3003.12,16046.44) 691,740.51(248045.68,1325371.48) 19.90(1.82,60.47) 3246.10(296.31,9865.42) −13.82(−16.17,−11.40)
Measles Republic of Guatemala 8758.43(8583.58,8944.54) 178.35(174.79,182.14) 0.00(0.00,0.00) 0.00(0.00,0.00) −21.38(−33.02,−7.71) 1401.59(1130.12,1661.37) 68,828.61(55497.73,81586.01) 0.00(0.00,0.00) 0.00(0.00,0.00) −46.33(−51.79,−40.24)
Measles Republic of Guinea 234,688.78(80565.08,502628.59) 7139.51(2450.89,15290.56) 128,586.00(93922.34,169546.95) 1722.64(1258.26,2271.39) −6.22(−8.07,−4.34) 23,383.74(8342.70,43713.47) 768,666.48(274239.94,1436941.90) 2291.97(1218.94,3709.31) 171,083.10(90987.40,276879.77) −8.51(−10.13,−6.86)
Measles Republic of Guinea−Bissau 33,242.54(11625.56,73426.34) 5652.57(1976.81,12485.44) 20,419.61(15994.82,25464.12) 1825.58(1429.99,2276.58) −4.11(−5.90,−2.28) 21,859.46(8322.05,40202.35) 128,554.58(48941.64,236428.35) 3216.24(1827.55,5113.11) 35,974.45(20441.54,57191.44) −6.25(−7.60,−4.87)
Measles Republic of Guyana 1.12(0.00,3.24) 0.29(0.00,0.85) 0.00(0.00,0.00) 0.00(0.00,0.00) 1065.22(NaN,NaN) 0.12(0.04,0.22) 0.46(0.16,0.83) 0.00(0.00,0.00) 0.00(0.00,0.00) −41.58(NaN,NaN)
Measles Republic of Haiti 1427.02(1350.48,1499.90) 42.64(40.36,44.82) 0.00(0.00,0.00) 0.00(0.00,0.00) −25.46(−55.61,25.15) 60.45(37.92,93.85) 2022.98(1268.89,3140.58) 0.00(0.00,0.00) 0.00(0.00,0.00) −27.66(−56.91,21.44)
Measles Republic of Honduras 8306.26(8130.48,8492.15) 306.10(299.62,312.95) 0.00(0.00,0.00) 0.00(0.00,0.00) −60.37(−80.35,−20.07) 316.04(202.38,475.26) 8576.17(5491.66,12896.62) 0.00(0.00,0.00) 0.00(0.00,0.00) −61.48(−80.87,−22.44)
Measles Republic of Iceland 13.68(6.83,21.47) 16.18(8.08,25.41) 0.02(0.00,0.04) 0.02(0.00,0.04) −8.01(−15.85,0.56) 0.11(0.08,0.15) 0.10(0.07,0.13) 0.01(0.00,0.01) 0.01(0.00,0.01) −6.45(−8.37,−4.50)
Measles Republic of India 21,808,962.03(7488683.15,47295953.57) 5313.86(1824.66,11523.90) 453,746.10(303892.43,601198.72) 90.65(60.71,120.10) −8.06(−10.25,−5.81) 3408.16(1249.29,6751.15) 13,987,643.96(5127269.60,27707806.02) 19.38(9.27,35.85) 97,011.63(46424.37,179433.74) −11.27(−13.39,−9.10)
Measles Republic of Indonesia 3,882,663.52(1346705.75,8582051.06) 4439.19(1539.74,9812.17) 117,776.57(80370.50,158092.71) 130.55(89.08,175.23) −7.86(−9.56,−6.13) 1634.71(556.95,3451.78) 1,429,775.39(487129.07,3019043.74) 20.56(10.21,36.41) 18,544.91(9212.55,32852.57) −10.39(−11.96,−8.79)
Measles Republic of Iraq 350,121.95(122282.13,757086.32) 3399.73(1187.37,7351.40) 41.34(25.57,70.87) 0.23(0.14,0.40) −16.53(−20.24,−12.64) 1466.83(531.85,2982.85) 151,062.39(54773.14,307190.30) 0.77(0.00,3.25) 135.49(0.08,572.93) −19.16(−21.76,−16.47)
Measles Republic of Italy 5027.05(4910.94,5160.79) 36.91(36.06,37.89) 8.37(3.68,14.57) 0.08(0.04,0.14) −13.21(−18.23,−7.88) 0.99(0.79,1.16) 135.16(107.41,157.89) 0.16(0.10,0.23) 16.26(10.29,24.23) −7.55(−12.21,−2.63)
Measles Republic of Kazakhstan 272.56(241.97,302.51) 4.10(3.64,4.55) 2.06(0.00,5.22) 0.03(0.00,0.08) −6.11(−14.17,2.71) 0.17(0.10,0.27) 11.56(6.53,17.74) 0.00(0.00,0.01) 0.23(0.08,0.52) −10.36(−16.92,−3.29)
Measles Republic of Kenya 691,549.69(241420.02,1521601.05) 5014.20(1750.46,11032.63) 234,532.78(88445.82,416417.10) 953.37(359.53,1692.72) −7.21(−9.25,−5.13) 3589.90(1259.22,7575.09) 495,112.66(173669.27,1044743.43) 291.64(127.41,534.75) 71,744.01(31343.11,131551.64) −9.09(−11.04,−7.10)
Measles Republic of Kiribati 2170.72(752.62,4733.26) 5922.33(2053.36,12913.66) 217.04(68.77,508.10) 406.09(128.67,950.70) −4.76(−7.23,−2.23) 2702.24(935.16,5897.02) 990.46(342.77,2161.44) 208.30(66.66,472.31) 111.32(35.63,252.43) −5.86(−8.02,−3.66)
Measles Republic of Korea 3273.94(3167.98,3380.77) 20.56(19.89,21.23) 0.00(0.00,0.00) 0.00(0.00,0.00) −15.08(−23.69,−5.50) 2.15(1.39,3.24) 343.16(221.00,516.21) 0.00(0.00,0.00) 0.01(0.00,0.10) −19.37(−27.25,−10.64)
Measles Republic of Latvia 20.43(12.69,29.28) 2.72(1.69,3.89) 0.05(0.01,0.10) 0.01(0.00,0.03) −4.92(−12.48,3.30) 0.01(0.01,0.01) 0.06(0.04,0.09) 0.03(0.02,0.06) 0.13(0.06,0.22) 9.02(0.36,18.43)
Measles Republic of Liberia 132,868.66(47569.62,261258.67) 9725.66(3481.98,19123.50) 26,856.12(20244.07,35330.01) 962.57(725.58,1266.29) −6.91(−9.93,−3.80) 17,084.35(6034.37,32333.96) 233,400.53(82439.46,441735.48) 1019.76(496.06,1793.72) 28,451.66(13840.37,50045.59) −9.47(−12.29,−6.56)
Measles Republic of Lithuania 185.11(160.64,212.43) 16.71(14.50,19.18) 5.31(2.96,8.47) 0.99(0.55,1.58) −5.75(−12.72,1.77) 0.04(0.03,0.06) 0.48(0.32,0.68) 0.00(0.00,0.00) 0.01(0.01,0.02) −5.83(−10.39,−1.03)
Measles Republic of Madagascar 378,424.77(131428.59,835256.93) 5626.31(1954.04,12418.36) 86.85(82.21,113.97) 0.58(0.55,0.76) −9.35(−14.31,−4.09) 6995.05(2311.21,14836.87) 470,485.78(155451.36,997925.74) 49.07(0.02,156.79) 7333.56(2.40,23429.95) −8.50(−11.18,−5.74)
Measles Republic of Malawi 314,108.60(110521.95,689418.87) 5635.96(1983.07,12370.05) 39,334.03(17270.73,64336.42) 371.40(163.07,607.47) −9.84(−12.36,−7.25) 11,974.78(3993.46,26859.62) 667,388.95(222566.87,1496964.17) 329.34(103.55,637.81) 34,879.67(10967.21,67549.41) −12.15(−14.43,−9.81)
Measles Republic of Maldives 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −20.81(−29.52,−11.03) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −29.29(−36.44,−21.34)
Measles Republic of Mali 366,590.20(127198.58,775496.25) 7412.06(2571.82,15679.69) 325,210.28(241298.02,418038.22) 2284.89(1695.33,2937.09) −6.29(−8.36,−4.18) 28,627.43(10510.82,55602.53) 1,415,873.88(519851.07,2750025.59) 4151.79(2076.02,7198.86) 590,927.29(295480.95,1024619.24) −8.50(−10.29,−6.68)
Measles Republic of Malta 5.75(1.95,10.71) 4.99(1.69,9.29) 0.04(0.01,0.07) 0.04(0.01,0.08) −4.58(−9.60,0.72) 0.10(0.06,0.13) 0.11(0.07,0.15) 0.00(0.00,0.00) 0.00(0.00,0.00) −6.10(−10.64,−1.34)
Measles Republic of Mauritius 14,851.10(5213.45,32706.10) 3447.22(1210.14,7591.70) 39.88(22.32,54.47) 13.43(7.52,18.34) −11.88(−13.99,−9.71) 8.61(2.70,19.94) 37.08(11.65,85.91) 0.03(0.02,0.05) 0.10(0.05,0.16) −11.79(−13.91,−9.62)
Measles Republic of Moldova 3168.98(3069.89,3279.90) 200.41(194.14,207.42) 0.00(0.00,0.00) 0.00(0.00,0.00) −12.11(−19.09,−4.52) 0.93(0.66,1.24) 14.75(10.42,19.58) 0.00(0.00,0.00) 0.00(0.00,0.02) −13.13(−19.35,−6.44)
Measles Republic of Mozambique 497,544.83(172603.14,1059744.89) 6571.97(2279.88,13997.97) 30,263.21(21377.56,39633.39) 170.46(120.41,223.23) −9.62(−11.88,−7.31) 13,955.56(4638.78,29274.63) 1,056,534.57(351188.59,2216296.22) 187.08(95.22,330.01) 33,215.03(16905.75,58591.08) −11.28(−13.36,−9.16)
Measles Republic of Namibia 42,817.81(14779.92,93029.97) 5621.50(1940.44,12213.79) 18.79(6.74,35.87) 1.75(0.63,3.35) −16.26(−21.05,−11.18) 2495.79(862.12,4972.63) 19,009.89(6566.56,37875.53) 4.07(0.47,15.61) 43.60(5.08,167.22) −15.85(−20.41,−11.04)
Measles Republic of Nauru 101.95(34.42,254.91) 1956.70(660.57,4892.38) 3.05(0.92,7.22) 59.52(17.87,140.86) −6.20(−8.98,−3.34) 607.19(193.16,1430.81) 31.64(10.06,74.55) 21.58(6.19,53.63) 1.11(0.32,2.75) −6.98(−9.64,−4.24)
Measles Republic of Nicaragua 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −90.29(−99.48,81.01) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −90.66(−99.52,83.64)
Measles Republic of Niue 12.24(4.16,26.00) 1197.44(406.68,2543.10) 0.12(0.04,0.30) 23.34(7.01,56.56) −10.09(−12.76,−7.34) 286.43(96.11,621.36) 2.93(0.98,6.35) 5.42(1.61,13.43) 0.03(0.01,0.07) −11.67(−14.15,−9.11)
Measles Republic of Palau 137.27(49.59,314.29) 2226.50(804.36,5097.81) 26.28(8.27,58.89) 593.43(186.67,1329.97) −3.10(−4.96,−1.21) 288.08(94.13,668.97) 17.76(5.80,41.24) 72.58(23.73,169.68) 3.21(1.05,7.51) −4.38(−6.10,−2.62)
Measles Republic of Panama 1854.89(1776.60,1938.50) 170.64(163.44,178.33) 0.00(0.00,0.00) 0.00(0.00,0.00) −23.85(−45.95,7.28) 14.97(9.12,22.82) 162.75(99.19,248.09) 0.00(0.00,0.00) 0.00(0.00,0.00) −31.31(−41.25,−19.68)
Measles Republic of Paraguay 1382.36(1309.69,1457.17) 66.81(63.30,70.43) 0.00(0.00,0.00) 0.00(0.00,0.00) −38.06(−56.54,−11.72) 22.52(15.48,32.65) 465.91(320.20,675.61) 0.00(0.00,0.00) 0.00(0.00,0.00) −40.08(−57.97,−14.57)
Measles Republic of Peru 708.45(661.27,763.67) 6.65(6.21,7.17) 0.00(0.00,0.00) 0.00(0.00,0.00) −19.35(−29.43,−7.83) 2.47(1.65,3.46) 262.61(175.81,368.87) 0.00(0.00,0.00) 0.00(0.00,0.00) −21.84(−30.18,−12.51)
Measles Republic of Poland 55,808.00(55376.93,56267.33) 448.27(444.81,451.96) 13.41(6.87,21.01) 0.17(0.09,0.27) −9.18(−14.85,−3.14) 2.14(1.69,2.67) 266.96(210.57,332.80) 0.00(0.00,0.00) 0.04(0.02,0.06) −13.28(−17.33,−9.03)
Measles Republic of Rwanda 196,472.60(69612.52,431507.64) 4747.23(1682.00,10426.22) 9973.59(5972.21,14606.14) 154.92(92.76,226.87) −10.71(−12.51,−8.87) 6612.07(2145.15,14743.41) 273,652.14(88780.65,610182.11) 117.87(48.99,211.56) 7588.39(3154.31,13620.50) −12.35(−14.08,−10.58)
Measles Republic of San Marino 0.83(0.00,2.50) 13.85(0.00,41.86) 0.00(0.00,0.01) 0.06(0.00,0.20) −8.74(−16.01,−0.84) 1.09(0.00,3.93) 0.06(0.00,0.24) 0.03(0.00,0.16) 0.00(0.00,0.01) −10.40(−15.71,−4.77)
Measles Republic of Senegal 259,265.27(90710.92,572799.75) 5830.19(2039.85,12880.76) 58,357.88(36768.88,80891.59) 719.11(453.08,996.78) −8.13(−11.19,−4.97) 7471.25(2461.35,15989.59) 332,242.23(109454.97,711047.65) 396.64(186.90,655.02) 32,188.94(15167.34,53156.82) −10.04(−12.77,−7.21)
Measles Republic of Serbia 4853.74(4717.99,4984.49) 167.31(162.63,171.81) 0.97(0.00,2.97) 0.05(0.00,0.16) −13.39(−21.94,−3.91) 35.28(22.49,52.44) 1023.47(652.39,1521.28) 1.40(0.51,2.85) 26.21(9.57,53.47) −11.64(−20.61,−1.66)
Measles Republic of Seychelles 752.28(271.87,1653.64) 2407.95(870.21,5293.06) 1.72(0.95,2.54) 5.65(3.12,8.33) −10.25(−12.38,−8.07) 416.45(154.68,836.60) 130.11(48.32,261.37) 0.92(0.36,2.07) 0.28(0.11,0.63) −11.58(−13.52,−9.60)
Measles Republic of Sierra Leone 177,008.18(62144.91,370520.84) 8025.01(2817.46,16798.29) 5668.18(3452.79,8238.14) 124.56(75.87,181.03) −12.13(−14.81,−9.36) 19,428.18(6768.61,39057.25) 428,528.44(149295.63,861487.91) 168.83(76.56,313.80) 7682.68(3483.88,14280.11) −13.88(−16.44,−11.24)
Measles Republic of Singapore 138.68(116.06,161.87) 15.06(12.60,17.58) 0.96(0.00,2.84) 0.09(0.00,0.27) −8.77(−12.98,−4.36) 0.05(0.03,0.07) 0.45(0.32,0.61) 0.00(0.00,0.00) 0.00(0.00,0.01) −8.98(−12.73,−5.08)
Measles Republic of Slovenia 40.77(29.14,53.95) 7.32(5.23,9.69) 0.09(0.01,0.37) 0.02(0.00,0.09) −5.61(−11.81,1.03) 0.02(0.02,0.03) 0.13(0.09,0.19) 0.00(0.00,0.00) 0.00(0.00,0.01) −5.18(−10.96,0.98)
Measles Republic of South Africa 742,594.96(263851.24,1642201.03) 4214.09(1497.31,9319.19) 20,650.39(13682.36,28981.77) 103.68(68.69,145.51) −6.05(−8.73,−3.30) 1430.17(498.12,3086.34) 252,020.79(87776.97,543866.00) 16.76(8.12,33.01) 3339.01(1616.75,6574.21) −8.23(−10.90,−5.49)
Measles Republic of South Sudan 204,815.19(70941.43,438190.67) 6232.84(2158.85,13334.80) 7320.55(4354.51,10522.31) 133.41(79.36,191.76) −9.56(−11.40,−7.69) 12,298.24(4204.24,25964.98) 404,128.58(138154.01,853226.89) 94.47(13.22,336.45) 5184.13(725.59,18462.38) −10.38(−12.33,−8.40)
Measles Republic of Sudan 671,302.78(229921.01,1454997.04) 6077.27(2081.46,13172.01) 12,548.22(7814.04,17728.68) 58.70(36.56,82.94) −13.32(−15.42,−11.16) 7844.82(2592.23,16542.74) 866,548.36(286341.05,1827331.22) 24.43(8.91,46.85) 5221.86(1903.92,10013.67) −17.04(−19.08,−14.95)
Measles Republic of Suriname 34.41(23.65,46.84) 20.13(13.83,27.39) 0.00(0.00,0.00) 0.00(0.00,0.00) NA(NA,NA) 6.83(3.72,10.59) 11.67(6.37,18.11) 0.00(0.00,0.00) 0.00(0.00,0.00) NA(NA,NA)
Measles Republic of Tajikistan 6877.94(6714.14,7036.73) 239.28(233.58,244.80) 12.76(6.39,21.30) 0.29(0.14,0.48) −17.07(−24.73,−8.63) 95.33(63.63,133.79) 2740.19(1829.01,3845.75) 0.11(0.01,0.27) 5.01(0.60,11.93) −18.00(−25.53,−9.70)
Measles Republic of the Congo 59,057.23(20647.62,131010.55) 4451.49(1556.33,9875.03) 11,318.36(6801.62,16298.52) 455.13(273.50,655.39) −6.17(−8.75,−3.50) 2369.88(757.12,5280.57) 31,440.87(10044.65,70056.46) 78.48(36.89,141.40) 1951.72(917.51,3516.35) −9.23(−11.61,−6.78)
Measles Republic of the Gambia 26,885.91(9450.04,59196.75) 4785.75(1682.13,10537.14) 7046.78(4499.03,10330.35) 556.35(355.20,815.59) −8.03(−10.52,−5.47) 9672.16(3355.01,20236.57) 54,337.38(18848.15,113687.31) 549.87(283.69,1004.55) 6964.80(3593.32,12723.82) −10.31(−12.48,−8.09)
Measles Republic of the Marshall Islands 1351.26(465.86,2960.49) 5045.39(1739.47,11054.02) 0.68(0.15,2.14) 2.95(0.65,9.27) −9.41(−13.89,−4.71) 1708.74(667.15,3198.30) 457.63(178.68,856.57) 1.20(0.24,3.40) 0.28(0.05,0.78) −10.10(−14.19,−5.81)
Measles Republic of the Niger 347,636.22(120722.67,739868.26) 7165.40(2488.31,15250.00) 132,328.04(91445.79,175915.61) 848.98(586.69,1128.62) −7.90(−9.89,−5.85) 23,516.37(7416.55,48655.94) 1,140,919.12(359820.96,2360588.82) 1538.96(596.18,2944.30) 239,874.41(92925.62,458920.77) −9.46(−11.28,−7.60)
Measles Republic of the Philippines 1,441,246.62(504489.78,3179321.25) 4496.50(1573.94,9919.07) 2148.03(959.89,3536.49) 4.80(2.14,7.90) −8.23(−11.68,−4.64) 1427.23(472.11,3203.81) 457,464.31(151323.07,1026904.47) 6.60(0.76,25.33) 2953.93(342.34,11341.15) −8.71(−11.20,−6.15)
Measles Republic of the Union of Myanmar 905,362.67(312632.01,1987085.31) 4737.33(1635.85,10397.46) 9208.71(5321.10,12073.78) 44.34(25.62,58.14) −10.22(−11.73,−8.68) 7659.51(2782.38,15152.31) 1,463,828.30(531746.85,2895796.93) 33.43(8.95,77.63) 6942.16(1859.10,16122.75) −13.58(−14.97,−12.16)
Measles Republic of Trinidad and Tobago 511.00(468.87,552.31) 98.37(90.26,106.32) 0.00(0.00,0.00) 0.00(0.00,0.00) −57.67(−79.62,−12.07) 0.31(0.22,0.43) 1.60(1.13,2.22) 0.01(0.00,0.02) 0.03(0.01,0.07) −8.51(−17.60,1.59)
Measles Republic of Tunisia 42,071.84(14195.81,89739.28) 1054.42(355.78,2249.07) 23.29(23.29,23.29) 0.65(0.65,0.65) −5.11(−9.43,−0.57) 516.00(164.17,1152.73) 20,588.66(6550.31,45994.52) 1.31(0.07,6.49) 47.12(2.56,232.79) −8.55(−11.22,−5.81)
Measles Republic of Turkey 1,034,152.49(363054.44,2278614.12) 3875.90(1360.69,8540.02) 5095.99(1828.10,9283.88) 20.62(7.40,37.57) −6.53(−9.69,−3.26) 1834.86(640.16,3670.64) 489,571.29(170804.89,979387.30) 6.78(2.03,21.45) 1676.28(502.11,5301.39) −11.45(−13.75,−9.10)
Measles Republic of Uganda 641,698.53(224493.58,1413275.12) 6231.42(2180.02,13724.07) 19,346.68(11526.25,27780.90) 77.56(46.21,111.38) −7.88(−10.52,−5.16) 13,967.04(4699.85,29063.56) 1,438,295.69(483980.62,2992903.05) 122.56(49.76,237.08) 30,570.04(12410.88,59135.10) −10.30(−12.61,−7.92)
Measles Republic of Uzbekistan 3898.24(3780.12,4023.97) 36.51(35.41,37.69) 9.80(4.50,18.07) 0.08(0.04,0.14) −11.25(−18.44,−3.43) 28.64(14.56,46.76) 3058.03(1553.97,4991.58) 0.40(0.06,1.19) 50.02(7.29,149.87) −11.07(−19.42,−1.84)
Measles Republic of Vanuatu 5588.28(1921.70,11936.64) 6696.71(2302.86,14304.26) 3279.09(1004.87,7510.63) 2224.04(681.55,5094.07) −7.30(−10.09,−4.43) 2936.89(1240.08,5211.56) 2450.78(1034.82,4348.95) 676.50(218.40,1542.18) 997.42(322.01,2273.77) −8.26(−10.75,−5.70)
Measles Republic of Yemen 531,777.61(183528.02,1149952.38) 6324.59(2182.76,13676.74) 51,822.65(37192.60,68395.64) 296.60(212.87,391.46) −11.35(−13.31,−9.33) 8354.75(2996.69,17017.58) 702,474.90(251964.53,1430853.62) 142.39(80.17,224.78) 24,878.30(14007.51,39274.33) −14.52(−16.34,−12.65)
Measles Republic of Zambia 245,143.01(86213.81,539534.78) 5215.26(1834.14,11478.26) 102,833.28(54467.38,158671.62) 983.65(521.01,1517.77) −9.72(−11.93,−7.46) 8844.29(3112.32,18737.81) 415,725.29(146294.42,880769.33) 697.81(197.99,1403.69) 72,950.66(20698.51,146745.31) −12.65(−14.73,−10.51)
Measles Republic of Zimbabwe 216,446.22(77910.22,488596.40) 3594.04(1293.68,8113.03) 6200.47(6200.47,6200.47) 77.66(77.66,77.66) −9.03(−11.72,−6.25) 2374.32(872.87,4826.38) 142,990.43(52567.41,290662.08) 46.55(4.38,125.13) 3716.44(349.60,9990.50) −7.86(−10.60,−5.03)
Measles Romania 4531.53(4403.29,4663.93) 60.40(58.69,62.16) 2.34(0.00,5.48) 0.06(0.00,0.14) −4.99(−14.77,5.92) 11.12(7.26,15.18) 834.10(544.64,1138.99) 1.69(0.42,3.43) 68.41(17.09,138.40) −4.92(−17.05,8.98)
Measles Russian Federation 18,014.09(17756.01,18278.68) 39.87(39.30,40.45) 0.83(0.00,2.55) 0.00(0.00,0.01) −13.21(−18.92,−7.09) 1.83(1.24,2.70) 828.04(559.07,1218.13) 0.01(0.00,0.01) 1.74(0.14,4.41) −12.21(−15.38,−8.93)
Measles Saint Kitts and Nevis 80.11(63.98,97.52) 436.04(348.27,530.81) 0.00(0.00,0.00) 0.00(0.00,0.00) −57.91(NaN,NaN) 1.48(0.94,2.13) 0.27(0.17,0.39) 0.00(0.00,0.00) 0.00(0.00,0.00) −19.58(NaN,NaN)
Measles Saint Lucia 28.50(19.85,38.75) 42.68(29.72,58.03) 0.00(0.00,0.00) 0.00(0.00,0.00) −43.01(−54.58,−28.49) 0.12(0.07,0.18) 0.08(0.05,0.12) 0.00(0.00,0.00) 0.00(0.00,0.00) −20.41(−21.72,−19.07)
Measles Saint Vincent and the Grenadines 0.92(0.00,2.86) 1.72(0.00,5.32) 0.00(0.00,0.00) 0.00(0.00,0.00) NA(NA,NA) 0.07(0.04,0.11) 0.04(0.02,0.06) 0.00(0.00,0.00) 0.00(0.00,0.00) NA(NA,NA)
Measles Slovak Republic 46.28(33.80,59.80) 2.64(1.93,3.41) 0.00(0.00,0.00) 0.00(0.00,0.00) −3.06(−16.33,12.31) 0.33(0.20,0.50) 5.81(3.56,8.73) 0.27(0.14,0.48) 3.04(1.53,5.39) −4.20(−14.72,7.63)
Measles Socialist Republic of Viet Nam 1,513,950.65(530648.10,3334329.12) 4496.85(1576.17,9903.88) 7095.26(4077.51,10861.80) 22.44(12.90,34.35) −11.15(−13.00,−9.27) 2301.68(909.27,4294.94) 774,905.31(306122.32,1445973.83) 5.26(1.74,16.47) 1663.41(549.89,5208.07) −14.10(−15.68,−12.49)
Measles Solomon Islands 9823.22(3427.48,21862.25) 5047.46(1761.14,11233.48) 1675.86(525.59,3858.30) 506.70(158.91,1166.56) −8.48(−12.71,−4.05) 3722.58(1452.16,6535.27) 7244.78(2826.15,12718.75) 453.31(149.22,977.09) 1499.29(493.55,3231.65) −8.95(−12.88,−4.84)
Measles State of Eritrea 142,978.56(49043.95,301683.51) 7269.64(2493.61,15338.89) 1011.95(356.83,2017.40) 31.46(11.09,62.72) −11.53(−14.07,−8.92) 10,463.63(3746.18,20770.93) 205,797.50(73679.50,408520.25) 36.31(8.43,83.24) 1168.01(271.06,2677.49) −12.42(−14.83,−9.94)
Measles State of Israel 226.89(201.63,256.91) 11.31(10.05,12.81) 0.00(0.00,0.00) 0.00(0.00,0.00) −2.48(−10.29,6.01) 2.29(1.35,3.28) 45.98(26.99,65.78) 0.00(0.00,0.00) 0.00(0.00,0.02) −13.67(−20.69,−6.03)
Measles State of Kuwait 30,574.66(10929.29,67467.51) 4457.24(1593.29,9835.55) 295.66(199.89,470.88) 26.99(18.25,42.98) −9.08(−11.27,−6.83) 11.38(3.81,25.49) 78.07(26.13,174.84) 0.07(0.04,0.12) 0.75(0.42,1.37) −9.07(−11.25,−6.82)
Measles State of Libya 85,067.05(30214.04,186270.42) 3685.29(1308.94,8069.63) 62.45(31.58,112.74) 2.99(1.51,5.40) −13.01(−17.39,−8.40) 898.40(316.46,1877.93) 20,737.65(7304.82,43348.02) 0.28(0.09,0.68) 5.85(1.95,14.22) −15.80(−20.03,−11.35)
Measles State of Qatar 7858.51(2760.84,17329.11) 5133.63(1803.53,11320.35) 94.66(52.20,159.62) 15.85(8.74,26.73) −13.17(−14.97,−11.33) 535.97(195.34,1080.50) 820.46(299.03,1654.02) 1.33(0.42,3.66) 7.94(2.49,21.85) −15.63(−17.11,−14.11)
Measles Sultanate of Oman 1247.87(1179.37,1313.96) 124.50(117.67,131.10) 4.80(0.97,8.75) 0.32(0.07,0.59) −12.48(−18.40,−6.12) 59.27(36.10,95.00) 594.01(361.81,952.14) 0.02(0.01,0.04) 0.29(0.07,0.63) −18.29(−24.22,−11.91)
Measles Swiss Confederation 1932.06(1852.37,2012.64) 122.50(117.45,127.61) 0.00(0.00,0.00) 0.00(0.00,0.00) −14.13(−17.89,−10.21) 5.77(4.15,7.62) 91.06(65.49,120.11) 0.00(0.00,0.00) 0.03(0.01,0.08) −18.11(−22.18,−13.84)
Measles Syrian Arab Republic 290,063.18(101867.82,638123.15) 3945.40(1385.59,8679.67) 1421.04(785.93,2239.24) 26.12(14.45,41.16) −10.45(−13.57,−7.21) 1920.80(706.88,3831.41) 141,215.85(51969.32,281682.64) 5.76(2.54,10.96) 313.52(138.20,596.23) −13.72(−16.43,−10.93)
Measles Taiwan (Province of China) 139,313.13(49563.43,331705.36) 1906.06(678.12,4538.35) 29.52(9.37,68.85) 0.73(0.23,1.70) −17.55(−20.31,−14.70) 5.20(1.87,12.06) 380.20(136.98,881.58) 0.00(0.00,0.01) 0.13(0.03,0.30) −15.64(−18.33,−12.85)
Measles Togolese Republic 110,068.33(38520.14,244033.57) 5112.98(1789.37,11336.04) 23,272.01(15106.18,32176.31) 557.36(361.79,770.61) −6.92(−9.75,−4.00) 8264.62(2903.96,16826.02) 177,914.42(62514.15,362217.82) 441.07(198.27,806.31) 18,416.36(8278.63,33666.56) −8.97(−11.64,−6.22)
Measles Tokelau 20.83(7.31,45.79) 2746.99(963.78,6037.24) 2.91(0.88,6.63) 569.30(172.04,1296.70) −1.76(−6.78,3.53) 970.68(355.38,1982.40) 7.36(2.70,15.03) 220.11(69.51,514.84) 1.13(0.36,2.63) −3.69(−8.32,1.18)
Measles Turkmenistan 2744.21(2648.16,2844.91) 145.56(140.47,150.91) 0.00(0.00,0.00) 0.00(0.00,0.00) −31.25(−41.92,−18.63) 44.68(29.66,61.67) 842.37(559.10,1162.69) 0.00(0.00,0.00) 0.03(0.01,0.06) −27.79(−33.66,−21.39)
Measles Tuvalu 315.15(111.68,662.98) 7375.11(2613.54,15515.10) 26.19(8.49,58.82) 533.18(172.72,1197.27) −8.44(−12.38,−4.32) 3564.49(1341.32,7055.15) 152.31(57.32,301.47) 173.87(56.11,393.96) 8.54(2.76,19.35) −10.49(−14.20,−6.62)
Measles Ukraine 6745.30(6580.59,6913.36) 44.81(43.72,45.93) 12.50(7.00,18.69) 0.15(0.08,0.22) −4.51(−12.66,4.41) 0.31(0.23,0.40) 46.34(34.21,59.71) 0.00(0.00,0.00) 0.06(0.02,0.18) −4.46(−13.40,5.40)
Measles Union of the Comoros 15,557.48(5413.93,33937.05) 5885.90(2048.26,12839.49) 2069.86(714.62,4145.68) 659.30(227.62,1320.50) −9.22(−12.85,−5.43) 8627.55(3074.67,16261.97) 22,804.15(8126.90,42983.26) 420.83(128.18,915.71) 1321.20(402.43,2874.86) −11.63(−15.00,−8.13)
Measles United Arab Emirates 16,909.70(5655.20,36382.60) 2391.69(799.87,5145.92) 517.03(323.31,718.72) 30.50(19.07,42.40) −8.55(−12.45,−4.48) 304.81(100.92,662.61) 2155.06(713.53,4684.79) 3.25(1.19,7.93) 55.10(20.23,134.40) −11.46(−15.08,−7.69)
Measles United Kingdom of Great Britain and Northern Ireland 27,469.85(27113.66,27792.58) 185.18(182.78,187.36) 1.92(0.02,4.67) 0.01(0.00,0.03) −13.04(−18.64,−7.06) 1.73(1.50,1.98) 257.01(222.98,293.02) 0.11(0.07,0.15) 16.80(10.22,23.28) −3.40(−5.78,−0.97)
Measles United Mexican States 68,338.66(67856.88,68835.03) 157.58(156.47,158.73) 0.00(0.00,0.00) 0.00(0.00,0.00) −15.93(−26.67,−3.62) 67.19(44.91,94.09) 29,138.18(19476.79,40802.67) 0.00(0.00,0.00) 0.00(0.00,0.00) −22.58(−31.15,−12.95)
Measles United Republic of Tanzania 720,456.64(253473.22,1587626.29) 4827.75(1698.51,10638.63) 339,941.88(197388.92,504469.63) 1101.62(639.66,1634.80) −8.14(−10.07,−6.16) 6550.17(2138.31,14908.09) 977,497.34(319105.31,2224768.19) 665.42(299.51,1253.41) 205,336.98(92422.93,386781.54) −9.90(−11.58,−8.19)
Measles United States of America 27,372.13(27049.39,27688.18) 36.97(36.53,37.39) 49.65(36.82,64.58) 0.06(0.05,0.08) −8.27(−13.44,−2.79) 2.70(1.77,3.91) 2002.15(1311.12,2893.32) 0.00(0.00,0.01) 2.07(0.47,4.88) −9.78(−14.82,−4.44)
Measles United States Virgin Islands 3.02(0.00,6.97) 7.24(0.00,16.72) 0.00(0.00,0.00) 0.00(0.00,0.00) −41.91(−74.30,31.27) 1.09(0.03,2.58) 0.45(0.01,1.08) 0.00(0.00,0.00) 0.00(0.00,0.00) −43.49(−75.19,28.73)
Meningitis American Samoa 17.07(13.29,21.17) 71.33(55.55,88.47) 8.70(6.59,11.45) 45.48(34.44,59.85) −1.61867 60.57(47.18,76.93) 253.15(197.19,321.53) 21.55(16.62,27.45) 112.65(86.89,143.51) −2.73(−2.98,−2.48)
Meningitis Antigua and Barbuda 13.23(10.60,15.90) 55.40(44.39,66.56) 8.11(6.32,10.18) 34.69(27.03,43.57) −1.98405 62.10(50.54,74.40) 259.95(211.57,311.44) 14.90(12.73,17.15) 63.79(54.49,73.39) −5.24(−5.69,−4.79)
Meningitis Arab Republic of Egypt 18,360.89(15165.43,22342.04) 65.76(54.31,80.01) 11,435.23(8764.45,14999.43) 24.57(18.83,32.22) −3.02923 128,952.84(106176.85,156670.29) 461.82(380.25,561.08) 24,083.17(18532.02,30872.84) 51.74(39.81,66.32) −6.22(−6.59,−5.86)
Meningitis Argentine Republic 5011.42(4188.20,6018.72) 38.47(32.15,46.20) 1417.32(1118.67,1788.45) 10.34(8.16,13.04) −4.25873 40,637.23(37761.87,43983.30) 311.95(289.88,337.64) 6187.57(5208.41,7292.31) 45.13(37.99,53.18) −5.55(−5.79,−5.30)
Meningitis Australia 567.41(448.56,702.93) 10.97(8.67,13.59) 256.13(195.25,338.69) 4.11(3.13,5.43) −3.48438 4724.13(4355.12,5075.41) 91.34(84.20,98.13) 1012.87(855.78,1188.45) 16.24(13.72,19.05) −5.54(−5.96,−5.12)
Meningitis Barbados 48.93(40.06,59.60) 57.63(47.18,70.20) 17.73(13.56,23.17) 26.72(20.42,34.91) −2.92306 240.07(204.90,277.00) 282.76(241.33,326.25) 43.68(31.95,59.72) 65.80(48.13,89.96) −5.23(−5.71,−4.74)
Meningitis Belize 66.11(54.93,78.16) 64.44(53.55,76.19) 47.66(36.14,62.47) 28.20(21.38,36.95) −2.85687 542.23(480.06,611.70) 528.61(468.00,596.33) 79.55(67.11,94.54) 47.06(39.70,55.93) −7.73(−8.11,−7.35)
Meningitis Bermuda 7.67(6.04,9.54) 48.25(38.01,60.02) 3.44(2.48,4.53) 29.89(21.56,39.38) −1.76046 25.00(21.02,29.31) 157.20(132.20,184.32) 2.74(2.16,3.34) 23.86(18.76,29.03) −6.35(−6.75,−5.94)
Meningitis Bolivarian Republic of Venezuela 4207.56(3524.66,4990.28) 46.36(38.83,54.98) 1762.13(1415.32,2187.27) 20.13(16.17,24.99) −2.51604 45,399.46(42712.98,48293.31) 500.21(470.61,532.09) 14,176.04(10554.70,19311.10) 161.98(120.60,220.65) −3.34(−4.32,−2.36)
Meningitis Bosnia and Herzegovina 420.28(330.03,527.30) 28.36(22.27,35.59) 100.04(74.52,133.54) 15.04(11.20,20.08) −2.33676 1167.99(950.49,1406.97) 78.83(64.15,94.95) 132.40(101.93,173.24) 19.91(15.33,26.05) −5.11(−5.78,−4.43)
Meningitis Brunei Darussalam 16.23(12.83,20.62) 14.11(11.16,17.93) 11.74(8.99,15.54) 9.09(6.96,12.03) −1.77883 86.72(69.06,112.80) 75.39(60.04,98.06) 39.67(29.85,51.12) 30.72(23.11,39.59) −2.89(−3.26,−2.52)
Meningitis Burkina Faso 30,514.17(24723.09,36771.27) 539.38(437.02,649.99) 19,374.65(15934.84,23225.13) 151.30(124.43,181.36) −4.24984 363,891.39(282247.84,468191.24) 6432.34(4989.16,8276.00) 221,971.51(128610.58,376179.60) 1733.37(1004.31,2937.57) −4.25(−5.05,−3.43)
Meningitis Canada 894.41(693.66,1165.62) 11.67(9.05,15.21) 526.53(398.21,697.19) 6.40(4.84,8.47) −2.13504 4321.45(4012.93,4617.12) 56.38(52.36,60.24) 942.03(818.81,1085.79) 11.45(9.95,13.19) −4.51(−4.81,−4.22)
Meningitis Central African Republic 6517.29(5431.17,7554.42) 435.32(362.77,504.59) 5349.22(4605.19,6133.80) 184.84(159.13,211.95) −2.6285 76,366.84(62028.21,103309.88) 5100.84(4143.11,6900.47) 48,805.15(32429.52,79001.54) 1686.42(1120.58,2729.83) −3.16(−3.62,−2.70)
Meningitis Commonwealth of Dominica 17.39(14.10,21.21) 53.06(43.03,64.72) 6.27(4.96,8.05) 32.29(25.54,41.46) −1.81501 93.62(72.24,119.06) 285.67(220.42,363.28) 30.00(21.07,44.16) 154.43(108.44,227.34) −2.14(−2.74,−1.53)
Meningitis Commonwealth of the Bahamas 57.15(46.29,69.63) 53.08(43.00,64.68) 25.84(19.41,34.22) 22.42(16.84,29.69) −2.92775 325.13(271.56,393.82) 301.99(252.24,365.80) 44.46(34.48,59.33) 38.58(29.91,51.47) −6.92(−7.28,−6.56)
Meningitis Cook Islands 5.39(3.93,7.20) 62.59(45.70,83.63) 2.66(1.86,3.71) 51.29(35.85,71.49) −1.05644 7.15(5.69,8.90) 83.03(66.06,103.40) 1.27(1.03,1.62) 24.41(19.80,31.22) −5.54(−6.18,−4.90)
Meningitis Czech Republic 780.19(600.99,1011.69) 25.63(19.74,33.24) 318.29(234.48,435.76) 14.33(10.56,19.62) −2.35727 3127.43(2862.23,3404.14) 102.74(94.03,111.84) 336.80(284.92,389.62) 15.17(12.83,17.55) −5.68(−6.12,−5.25)
Meningitis Democratic People’s Republic of Korea 4084.76(3292.02,4997.27) 52.44(42.26,64.16) 1187.35(917.96,1536.22) 17.98(13.90,23.27) −3.66202 26,973.40(18972.60,36208.32) 346.29(243.57,464.84) 5507.00(3886.52,8051.24) 83.41(58.87,121.95) −4.38(−4.83,−3.93)
Meningitis Democratic Republic of Sao Tome and Principe 79.31(63.51,95.91) 113.49(90.88,137.24) 27.37(21.82,34.14) 26.89(21.43,33.54) −5.13045 755.39(585.08,986.32) 1080.92(837.22,1411.36) 104.44(74.88,152.62) 102.59(73.56,149.92) −7.79(−8.50,−7.08)
Meningitis Democratic Republic of the Congo 68,298.85(56561.28,80657.29) 315.47(261.25,372.55) 44,901.19(37686.82,53171.05) 93.73(78.67,110.99) −4.24088 738,034.85(511928.58,1026909.33) 3408.91(2364.55,4743.19) 328,812.64(225476.21,585932.06) 686.36(470.65,1223.06) −4.98(−5.67,−4.27)
Meningitis Democratic Republic of Timor−Leste 677.67(547.58,831.62) 166.64(134.65,204.50) 249.29(211.42,292.22) 36.37(30.85,42.63) −5.22674 8152.22(5309.76,12678.21) 2004.66(1305.69,3117.61) 2801.54(2035.86,3956.33) 408.73(297.02,577.20) −5.42(−5.59,−5.24)
Meningitis Democratic Socialist Republic of Sri Lanka 3592.51(2877.63,4449.03) 49.62(39.75,61.45) 2564.07(1926.37,3373.99) 37.16(27.92,48.90) −1.35589 20,580.51(17133.83,25762.28) 284.26(236.65,355.83) 7335.26(5602.55,9511.98) 106.31(81.20,137.86) −2.61(−3.24,−1.98)
Meningitis Dominican Republic 4045.24(3292.63,4816.23) 115.51(94.02,137.52) 1266.80(1055.46,1493.14) 32.56(27.13,38.38) −3.85141 45,433.17(35918.88,55594.62) 1297.30(1025.63,1587.45) 7458.94(5360.33,10737.65) 191.71(137.77,275.98) −5.65(−6.03,−5.27)
Meningitis Eastern Republic of Uruguay 316.82(255.31,391.67) 29.42(23.71,36.37) 67.57(50.34,93.32) 7.48(5.57,10.33) −4.74318 2398.12(2212.24,2586.92) 222.66(205.40,240.19) 303.80(252.17,362.50) 33.63(27.92,40.13) −6.27(−6.49,−6.04)
Meningitis Federal Democratic Republic of Ethiopia 186,239.86(149585.85,225592.05) 632.02(507.63,765.57) 75,290.80(61976.21,89096.57) 131.63(108.35,155.77) −5.59894 1,854,006.45(1396109.62,2400425.74) 6291.76(4737.84,8146.08) 550,874.80(424680.96,687250.94) 963.10(742.48,1201.53) −6.44(−6.69,−6.19)
Meningitis Federal Democratic Republic of Nepal 7661.96(5950.87,9664.54) 74.04(57.50,93.39) 2414.75(1902.66,3044.63) 19.39(15.28,24.45) −3.99084 79,711.16(47127.68,165256.39) 770.24(455.39,1596.86) 20,534.86(14416.66,29346.71) 164.88(115.75,235.63) −3.97(−4.36,−3.58)
Meningitis Federal Republic of Germany 1391.82(1080.92,1774.60) 8.03(6.24,10.24) 305.81(228.98,406.14) 1.92(1.44,2.55) −4.04346 14,488.58(13679.42,15379.10) 83.60(78.93,88.74) 2118.15(1892.06,2360.16) 13.28(11.86,14.80) −5.32(−5.63,−5.01)
Meningitis Federal Republic of Nigeria 298,392.51(233386.93,368409.33) 615.00(481.02,759.31) 283,350.78(233951.86,337470.29) 221.76(183.10,264.12) −3.14971 3,180,394.90(2382663.30,4223444.16) 6554.95(4910.79,8704.72) 2,580,248.36(1483679.21,4154839.69) 2019.41(1161.19,3251.75) −3.28(−3.77,−2.78)
Meningitis Federal Republic of Somalia 16,418.85(13378.58,19758.81) 346.95(282.71,417.53) 25,564.43(21806.25,29510.87) 199.97(170.57,230.84) −1.48408 196,190.73(133923.77,284789.63) 4145.74(2829.97,6017.94) 252,933.81(159101.95,414289.73) 1978.46(1244.50,3240.59) −1.85(−2.27,−1.42)
Meningitis Federated States of Micronesia 48.57(38.88,58.80) 84.47(67.62,102.27) 12.96(9.97,16.43) 31.27(24.06,39.64) −3.59704 295.03(223.25,395.85) 513.12(388.28,688.46) 43.44(32.41,61.78) 104.83(78.20,149.07) −5.21(−5.41,−5.02)
Meningitis Federative Republic of Brazil 56,835.89(46385.11,68582.40) 84.59(69.03,102.07) 15,563.86(12192.78,19837.94) 24.35(19.08,31.04) −5.06535 507,653.51(457703.51,557554.06) 755.52(681.18,829.78) 41,081.89(34310.66,48538.80) 64.27(53.68,75.94) −8.04(−8.42,−7.67)
Meningitis French Republic 2218.40(1693.99,2825.63) 13.74(10.49,17.50) 765.36(591.08,1003.80) 4.86(3.75,6.37) −3.27533 13,581.28(12809.37,14409.01) 84.14(79.35,89.26) 3289.96(2805.29,3768.97) 20.89(17.81,23.93) −4.46(−4.81,−4.12)
Meningitis Gabonese Republic 1114.44(932.60,1319.43) 219.30(183.52,259.64) 727.89(609.09,860.21) 88.01(73.65,104.01) −3.09067 9006.53(7280.18,11250.01) 1772.31(1432.60,2213.78) 3899.50(2558.62,5832.59) 471.50(309.37,705.23) −3.24(−3.80,−2.68)
Meningitis Georgia 850.71(682.20,1042.09) 47.35(37.97,58.00) 157.93(122.71,202.36) 16.99(13.21,21.78) −3.15088 4670.91(4099.34,5383.38) 259.95(228.14,299.61) 178.24(147.32,217.28) 19.18(15.85,23.38) −7.99(−8.45,−7.53)
Meningitis Grand Duchy of Luxembourg 15.08(11.60,19.46) 17.09(13.15,22.05) 6.91(5.12,9.31) 5.12(3.80,6.90) −3.83371 75.77(68.10,84.79) 85.88(77.19,96.10) 19.36(15.89,23.49) 14.35(11.78,17.41) −6.21(−6.91,−5.51)
Meningitis Greenland 16.08(12.84,19.44) 89.87(71.77,108.65) 2.16(1.67,2.67) 14.02(10.88,17.39) −5.90563 185.37(132.96,257.66) 1036.08(743.13,1440.09) 21.90(14.30,30.77) 142.51(93.06,200.16) −6.18(−6.78,−5.57)
Meningitis Grenada 24.65(20.07,29.62) 58.48(47.61,70.26) 8.99(6.75,11.51) 29.88(22.43,38.23) −2.20432 138.06(115.60,167.20) 327.48(274.20,396.59) 9.19(7.81,10.90) 30.54(25.95,36.22) −6.94(−7.45,−6.43)
Meningitis Guam 35.35(27.42,44.58) 65.28(50.65,82.34) 25.35(19.31,32.39) 52.29(39.82,66.80) −0.93671 97.93(77.27,116.95) 180.87(142.70,215.99) 39.71(31.26,49.68) 81.91(64.48,102.47) −1.83(−2.46,−1.20)
Meningitis Hashemite Kingdom of Jordan 709.92(564.30,890.52) 33.86(26.91,42.47) 951.34(723.90,1238.40) 19.32(14.70,25.14) −2.18881 4749.09(3696.49,6367.92) 226.51(176.31,303.72) 2249.57(1864.38,2739.70) 45.68(37.85,55.63) −5.49(−5.74,−5.23)
Meningitis Hellenic Republic 526.05(401.51,672.70) 18.72(14.29,23.93) 115.26(87.01,155.02) 6.05(4.57,8.14) −3.44095 1406.10(1312.19,1510.46) 50.03(46.69,53.74) 336.98(288.92,393.01) 17.69(15.16,20.63) −3.37(−3.71,−3.04)
Meningitis Hungary 808.39(627.96,1033.32) 27.85(21.64,35.60) 169.94(124.69,230.48) 9.06(6.65,12.29) −3.83531 4978.99(4541.69,5506.18) 171.56(156.49,189.72) 535.13(432.32,648.14) 28.53(23.05,34.56) −5.02(−5.48,−4.55)
Meningitis Independent State of Papua New Guinea 3787.06(3153.43,4527.70) 177.91(148.14,212.70) 4315.78(3648.22,5102.05) 88.09(74.47,104.14) −2.94896 20,698.58(15705.68,27843.95) 972.38(737.83,1308.06) 17,726.43(11443.48,27500.03) 361.83(233.59,561.33) −4.88(−5.62,−4.13)
Meningitis Independent State of Samoa 71.24(56.88,87.72) 77.78(62.10,95.77) 40.80(31.70,51.21) 40.42(31.40,50.73) −2.38028 335.63(238.10,460.88) 366.43(259.95,503.17) 117.60(81.31,165.23) 116.50(80.55,163.68) −3.65(−3.79,−3.52)
Meningitis Ireland 216.09(166.23,276.97) 16.26(12.51,20.84) 63.46(47.23,85.64) 4.80(3.57,6.48) −4.293 1165.48(1071.53,1255.26) 87.71(80.64,94.46) 194.20(166.43,227.29) 14.69(12.59,17.20) −5.87(−6.67,−5.05)
Meningitis Islamic Republic of Afghanistan 21,560.32(17344.53,26257.55) 386.87(311.23,471.16) 13,201.47(10892.75,15687.35) 74.26(61.28,88.25) −5.43098 258,858.97(180985.83,345330.45) 4644.91(3247.57,6196.53) 151,449.97(96644.27,246272.62) 851.96(543.66,1385.37) −5.56(−6.14,−4.98)
Meningitis Islamic Republic of Iran 13,217.02(10516.75,16271.57) 41.95(33.38,51.64) 2946.32(2237.91,3867.38) 11.40(8.66,14.96) −3.78714 108,148.13(87259.50,146455.29) 343.22(276.93,464.80) 6179.55(5140.99,7412.22) 23.90(19.88,28.67) −6.23(−7.20,−5.26)
Meningitis Islamic Republic of Mauritania 2414.40(1997.85,2926.00) 212.93(176.19,258.04) 1569.35(1295.45,1860.34) 67.29(55.55,79.77) −4.07058 24,917.69(18736.91,33338.77) 2197.48(1652.40,2940.13) 11,107.27(8135.31,15538.59) 476.26(348.83,666.27) −4.95(−5.74,−4.15)
Meningitis Islamic Republic of Pakistan 173,507.94(140207.66,210151.28) 284.61(229.99,344.72) 105,398.27(87315.34,124951.82) 96.50(79.94,114.40) −3.29147 1,894,736.62(1522273.59,2302685.44) 3107.99(2497.03,3777.16) 915,829.81(652873.61,1317545.76) 838.49(597.74,1206.28) −3.52(−3.85,−3.20)
Meningitis Jamaica 639.41(527.05,756.18) 58.53(48.24,69.21) 264.97(203.50,344.57) 32.50(24.96,42.26) −2.29184 3858.78(3437.45,4381.01) 353.20(314.64,401.00) 388.61(302.89,488.80) 47.66(37.15,59.95) −6.68(−7.19,−6.15)
Meningitis Japan 6240.96(4191.88,9113.46) 18.71(12.56,27.32) 2572.45(1855.29,3548.58) 12.12(8.74,16.71) −2.17902 9938.30(9533.61,10419.76) 29.79(28.57,31.23) 1483.24(1334.98,1638.83) 6.99(6.29,7.72) −4.63(−4.88,−4.37)
Meningitis Kingdom of Bahrain 117.21(92.49,148.78) 58.58(46.22,74.35) 86.54(62.74,117.25) 21.45(15.55,29.06) −3.8328 260.33(218.30,311.63) 130.10(109.10,155.74) 72.72(59.87,89.28) 18.02(14.84,22.12) −5.97(−6.27,−5.67)
Meningitis Kingdom of Belgium 586.84(436.57,771.33) 23.74(17.66,31.21) 234.60(174.72,315.15) 9.22(6.87,12.39) −3.17177 2078.35(1929.87,2226.80) 84.09(78.08,90.09) 487.61(412.59,571.51) 19.17(16.22,22.46) −5.12(−5.32,−4.91)
Meningitis Kingdom of Bhutan 514.44(419.61,625.22) 151.03(123.19,183.56) 112.23(94.59,131.96) 44.02(37.10,51.75) −4.28207 5470.67(2077.12,8221.84) 1606.12(609.82,2413.83) 614.16(422.83,874.14) 240.87(165.83,342.83) −6.43(−6.83,−6.03)
Meningitis Kingdom of Cambodia 7684.59(6219.17,9335.77) 134.97(109.23,163.97) 1359.68(1107.14,1629.89) 20.50(16.70,24.58) −6.34072 93,105.57(67985.89,127425.49) 1635.32(1194.11,2238.12) 15,589.81(10944.87,23569.28) 235.10(165.05,355.43) −6.43(−6.86,−6.01)
Meningitis Kingdom of Denmark 493.74(378.48,628.05) 39.49(30.27,50.23) 150.12(113.45,203.84) 11.60(8.77,15.75) −4.30336 2628.72(2428.51,2826.22) 210.25(194.24,226.05) 480.73(407.54,558.51) 37.14(31.49,43.15) −6.20(−6.71,−5.68)
Meningitis Kingdom of Eswatini 468.15(384.61,559.17) 98.12(80.61,117.20) 245.95(208.73,289.18) 45.97(39.01,54.05) −2.07371 5488.43(3996.28,7075.95) 1150.31(837.57,1483.03) 2651.05(1896.20,3649.88) 495.52(354.43,682.21) −2.21(−2.91,−1.50)
Meningitis Kingdom of Lesotho 754.90(632.64,908.43) 90.16(75.56,108.49) 503.39(429.94,591.24) 60.01(51.26,70.48) −1.12564 7701.26(5724.64,10401.25) 919.75(683.69,1242.21) 5020.84(3681.30,6630.86) 598.56(438.87,790.50) −0.82(−1.33,−0.29)
Meningitis Kingdom of Morocco 9031.59(7378.48,11011.25) 72.37(59.12,88.23) 2420.11(1886.35,3073.36) 18.74(14.61,23.80) −4.65532 66,343.89(47128.84,97063.78) 531.61(377.64,777.76) 6220.90(4157.13,9884.28) 48.17(32.19,76.53) −7.45(−7.97,−6.92)
Meningitis Kingdom of Norway 441.30(326.78,586.36) 39.67(29.37,52.70) 256.74(186.13,348.92) 20.68(14.99,28.11) −3.29598 1788.28(1669.28,1898.49) 160.74(150.04,170.64) 296.30(264.29,328.95) 23.87(21.29,26.50) −6.35(−6.93,−5.77)
Meningitis Kingdom of Saudi Arabia 2695.70(2093.45,3405.80) 32.83(25.49,41.48) 1318.54(952.91,1828.97) 13.01(9.40,18.05) −3.61912 21,124.00(15530.06,29454.76) 257.25(189.13,358.71) 1515.93(1179.55,2026.32) 14.96(11.64,20.00) −9.29(−9.63,−8.96)
Meningitis Kingdom of Spain 1272.34(999.93,1606.29) 11.41(8.97,14.41) 202.51(151.81,263.71) 2.30(1.72,2.99) −4.68165 12,362.47(11683.75,13043.01) 110.90(104.81,117.01) 1209.47(986.62,1588.56) 13.73(11.20,18.04) −6.40(−6.94,−5.84)
Meningitis Kingdom of Sweden 430.12(314.25,576.21) 20.41(14.91,27.35) 234.43(166.23,327.22) 9.71(6.88,13.55) −2.43525 1174.72(1096.83,1256.85) 55.75(52.06,59.65) 469.29(410.33,525.02) 19.43(16.99,21.74) −3.49(−4.24,−2.73)
Meningitis Kingdom of Thailand 9701.54(7919.29,11717.99) 42.65(34.81,51.51) 2710.97(2017.35,3601.69) 19.86(14.78,26.39) −2.58751 80,873.33(59125.52,108668.22) 355.54(259.93,477.73) 9211.05(7242.00,11454.62) 67.49(53.06,83.93) −5.32(−5.75,−4.89)
Meningitis Kingdom of the Netherlands 462.13(363.92,585.38) 12.06(9.49,15.27) 131.03(101.36,166.15) 3.55(2.75,4.50) −4.88243 5335.91(4967.30,5679.31) 139.21(129.59,148.17) 1209.70(1056.21,1365.42) 32.77(28.62,36.99) −5.65(−6.22,−5.07)
Meningitis Kingdom of Tonga 74.63(60.75,89.15) 139.86(113.84,167.07) 37.30(31.03,44.00) 75.23(62.59,88.74) −2.15309 628.46(480.10,805.05) 1177.72(899.69,1508.65) 236.76(168.31,328.80) 477.51(339.45,663.13) −2.91(−3.23,−2.60)
Meningitis Kyrgyz Republic 2364.66(1987.97,2740.34) 112.00(94.15,129.79) 811.81(631.05,1036.03) 28.76(22.36,36.70) −4.39409 16,939.81(14982.05,18984.86) 802.31(709.58,899.17) 1229.70(1051.96,1452.38) 43.56(37.27,51.45) −9.10(−9.59,−8.62)
Meningitis Lao People’s Democratic Republic 4061.86(3398.28,4722.52) 179.06(149.80,208.18) 966.89(821.18,1120.06) 32.32(27.45,37.44) −5.8717 48,557.06(33224.80,71837.88) 2140.51(1464.63,3166.78) 11,050.44(7355.63,16945.17) 369.39(245.88,566.44) −5.97(−6.42,−5.53)
Meningitis Lebanese Republic 486.88(372.44,623.11) 36.36(27.81,46.53) 277.82(200.81,381.03) 16.67(12.05,22.87) −2.61733 2490.86(1831.73,3578.20) 186.01(136.78,267.20) 415.36(314.30,549.71) 24.93(18.86,32.99) −6.39(−6.69,−6.09)
Meningitis Malaysia 3233.68(2572.73,3984.90) 38.76(30.84,47.76) 2019.62(1543.24,2614.41) 19.69(15.05,25.49) −2.28759 19,749.10(14839.47,25324.33) 236.72(177.87,303.54) 5876.16(4791.07,7196.33) 57.30(46.72,70.17) −3.74(−4.36,−3.12)
Meningitis Mongolia 2042.86(1670.58,2438.75) 179.97(147.17,214.84) 465.85(352.62,610.11) 35.49(26.86,46.48) −6.02443 18,734.81(9586.67,28618.47) 1650.47(844.55,2521.18) 1298.85(939.27,1764.49) 98.95(71.55,134.42) −9.06(−9.43,−8.70)
Meningitis Montenegro 49.42(37.07,65.03) 23.04(17.28,30.32) 19.33(13.94,26.67) 12.86(9.27,17.73) −2.35207 131.96(104.03,169.70) 61.52(48.49,79.11) 14.72(11.45,19.15) 9.79(7.61,12.73) −6.05(−6.53,−5.56)
Meningitis New Zealand 430.94(317.95,561.63) 39.14(28.88,51.01) 193.68(148.79,252.72) 14.86(11.41,19.39) −5.05609 1136.65(1050.19,1224.80) 103.23(95.38,111.24) 475.53(422.54,529.56) 36.48(32.42,40.63) −5.56(−6.91,−4.19)
Meningitis North Macedonia 306.21(248.28,373.74) 43.94(35.62,53.63) 52.14(38.93,68.84) 11.68(8.72,15.42) −3.97304 2516.05(1962.03,3130.46) 361.02(281.52,449.17) 80.60(64.81,107.00) 18.05(14.51,23.96) −8.12(−8.73,−7.51)
Meningitis Northern Mariana Islands 11.91(9.08,15.34) 73.44(55.97,94.61) 8.41(6.14,11.05) 56.08(40.94,73.69) −1.31204 10.88(8.35,13.97) 67.09(51.51,86.15) 6.17(5.04,7.53) 41.15(33.58,50.22) −1.54(−1.90,−1.17)
Meningitis Palestine 641.57(518.05,791.22) 53.75(43.40,66.29) 369.72(277.30,483.81) 15.35(11.52,20.09) −4.3683 4038.58(2923.09,5541.45) 338.36(244.90,464.27) 991.82(741.16,1284.04) 41.19(30.78,53.33) −6.39(−6.84,−5.93)
Meningitis People’s Democratic Republic of Algeria 6494.50(5173.99,7989.97) 48.05(38.28,59.11) 2766.53(2098.14,3637.71) 16.82(12.76,22.12) −3.01484 49,683.39(34573.74,71654.21) 367.57(255.79,530.12) 6980.99(4587.54,10484.81) 42.44(27.89,63.74) −5.67(−6.14,−5.20)
Meningitis People’s Republic of Bangladesh 55,978.95(45629.04,68017.30) 92.74(75.60,112.69) 18,077.88(14432.54,22499.66) 29.64(23.66,36.89) −3.436 502,657.33(198243.29,758097.42) 832.78(328.44,1255.97) 99,845.70(54531.31,151381.03) 163.71(89.41,248.21) −4.28(−4.91,−3.65)
Meningitis People’s Republic of China 258,612.78(198108.82,325784.72) 58.11(44.51,73.20) 28,518.32(21209.90,37894.11) 8.53(6.34,11.34) −6.67389 2,587,459.99(1965180.83,3239691.62) 581.40(441.57,727.95) 137,021.20(112290.35,162881.12) 40.99(33.59,48.72) −8.24(−8.80,−7.68)
Meningitis Plurinational State of Bolivia 2621.61(2106.96,3192.38) 78.28(62.92,95.33) 534.50(441.65,651.39) 11.76(9.71,14.33) −6.23561 31,657.97(24423.58,45831.26) 945.34(729.31,1368.56) 4289.05(3146.24,6231.54) 94.33(69.20,137.05) −7.20(−7.45,−6.95)
Meningitis Portuguese Republic 424.72(343.73,521.78) 14.25(11.53,17.50) 41.26(31.06,54.17) 2.15(1.62,2.83) −6.42238 5003.14(4660.79,5359.35) 167.84(156.35,179.79) 433.77(359.23,523.71) 22.63(18.74,27.32) −6.90(−7.51,−6.29)
Meningitis Principality of Andorra 1.22(0.90,1.69) 9.05(6.70,12.54) 0.44(0.32,0.60) 3.04(2.19,4.16) −4.06881 1.54(1.10,2.24) 11.45(8.17,16.67) 0.18(0.14,0.23) 1.26(0.97,1.60) −7.30(−7.67,−6.94)
Meningitis Principality of Monaco 0.58(0.44,0.77) 12.00(9.00,15.88) 0.29(0.21,0.39) 4.28(3.17,5.76) −3.52544 2.91(2.07,4.15) 59.98(42.62,85.56) 1.50(1.10,1.96) 22.12(16.23,29.02) −4.71(−5.49,−3.93)
Meningitis Puerto Rico 614.92(483.87,766.31) 46.16(36.32,57.53) 175.33(126.46,248.15) 26.83(19.35,37.97) −1.62723 1350.35(1234.73,1478.20) 101.37(92.69,110.97) 59.57(47.80,72.62) 9.12(7.31,11.11) −7.81(−8.42,−7.20)
Meningitis Republic of Albania 755.97(617.67,914.39) 52.28(42.72,63.24) 60.63(46.71,79.16) 9.82(7.57,12.83) −6.09669 6495.23(4992.32,8308.75) 449.21(345.27,574.64) 232.80(148.75,380.27) 37.72(24.10,61.62) −8.57(−8.85,−8.28)
Meningitis Republic of Angola 27,537.69(22446.81,33051.70) 477.59(389.29,573.22) 22,982.95(19348.06,26860.68) 123.06(103.60,143.83) −4.84024 323,415.00(240038.61,408223.51) 5608.98(4162.99,7079.81) 168,281.83(117711.55,233679.68) 901.07(630.29,1251.25) −5.98(−6.46,−5.51)
Meningitis Republic of Armenia 823.19(638.59,1060.27) 62.00(48.09,79.85) 340.48(244.66,471.18) 44.62(32.06,61.74) −1.03853 2168.83(1897.64,2469.74) 163.34(142.91,186.00) 118.46(96.42,150.84) 15.52(12.63,19.77) −7.25(−7.52,−6.98)
Meningitis Republic of Austria 523.80(454.87,596.98) 27.96(24.28,31.87) 169.04(132.66,219.71) 9.63(7.56,12.52) −3.16604 1886.72(1727.22,2050.45) 100.72(92.21,109.46) 286.97(246.41,327.95) 16.35(14.04,18.69) −5.49(−5.75,−5.22)
Meningitis Republic of Azerbaijan 2265.86(1863.03,2703.28) 72.39(59.52,86.36) 896.02(690.03,1135.80) 29.41(22.65,37.28) −3.17025 14,109.68(11616.36,16760.54) 450.77(371.12,535.46) 2024.91(1503.65,2916.94) 66.46(49.35,95.74) −6.23(−6.67,−5.80)
Meningitis Republic of Belarus 1855.48(1478.76,2270.15) 59.13(47.12,72.34) 495.92(373.19,642.33) 24.49(18.43,31.72) −2.45397 7565.87(6507.51,8824.85) 241.10(207.38,281.22) 956.84(759.49,1206.60) 47.24(37.50,59.58) −4.22(−4.51,−3.93)
Meningitis Republic of Benin 13,288.02(10845.82,16057.15) 463.05(377.94,559.54) 13,266.91(11196.04,15483.67) 176.51(148.96,206.00) −3.46847 147,401.17(112716.72,191920.68) 5136.47(3927.82,6687.83) 92,390.24(51203.37,160794.05) 1229.20(681.23,2139.27) −4.59(−5.05,−4.12)
Meningitis Republic of Botswana 640.77(537.24,763.51) 86.53(72.55,103.11) 438.02(365.48,512.07) 47.77(39.86,55.84) −2.06424 6027.66(4618.39,7787.88) 814.03(623.71,1051.74) 3478.31(2512.11,4840.49) 379.31(273.95,527.86) −1.99(−2.58,−1.41)
Meningitis Republic of Bulgaria 725.55(577.58,909.87) 30.70(24.44,38.50) 139.10(105.98,179.70) 10.75(8.19,13.88) −3.63605 4959.47(4460.43,5500.15) 209.85(188.74,232.73) 475.54(389.99,558.85) 36.74(30.13,43.18) −5.46(−5.79,−5.13)
Meningitis Republic of Burundi 11,225.65(9263.66,13436.79) 355.79(293.61,425.87) 6319.68(5403.19,7404.55) 86.87(74.28,101.79) −4.61471 133,941.36(100399.57,175170.99) 4245.19(3182.11,5551.94) 52,777.91(31873.77,93450.49) 725.52(438.16,1284.63) −5.45(−6.05,−4.84)
Meningitis Republic of Cabo Verde 325.87(261.19,391.78) 167.57(134.31,201.46) 140.18(110.99,176.26) 72.73(57.59,91.45) −3.27411 2144.43(1463.45,2948.49) 1102.70(752.53,1516.16) 263.53(208.22,331.71) 136.73(108.03,172.10) −7.96(−8.83,−7.08)
Meningitis Republic of Cameroon 20,172.64(16602.15,24174.54) 339.77(279.64,407.18) 22,879.77(19253.57,26701.82) 135.36(113.91,157.97) −3.11908 215,592.44(164985.38,285852.13) 3631.30(2778.90,4814.70) 157,210.22(95778.36,235132.89) 930.09(566.64,1391.09) −4.15(−4.75,−3.54)
Meningitis Republic of Chad 14,559.11(11898.88,17350.50) 412.99(337.53,492.17) 28,589.45(24142.02,33563.73) 261.10(220.48,306.53) −1.67209 156,540.76(117377.70,211427.62) 4440.52(3329.60,5997.47) 258,235.94(174818.05,371486.13) 2358.41(1596.58,3392.70) −2.21(−2.64,−1.79)
Meningitis Republic of Chile 1692.86(1367.30,2050.14) 32.09(25.92,38.87) 341.60(268.79,432.30) 6.98(5.49,8.83) −5.26416 13,178.84(12340.22,13999.07) 249.86(233.96,265.41) 1282.29(1146.73,1447.91) 26.20(23.43,29.59) −6.73(−6.98,−6.49)
Meningitis Republic of Colombia 6831.07(5683.46,8052.06) 45.38(37.76,53.49) 1706.34(1325.95,2204.07) 11.72(9.11,15.14) −4.80451 75,373.25(66228.58,86123.46) 500.72(439.97,572.14) 8465.40(6438.12,11131.59) 58.14(44.22,76.46) −7.16(−7.53,−6.78)
Meningitis Republic of Costa Rica 361.98(282.64,446.39) 25.52(19.93,31.48) 157.05(118.70,207.31) 11.47(8.67,15.14) −2.55728 2938.19(2707.68,3210.52) 207.18(190.93,226.39) 563.38(480.21,649.15) 41.15(35.08,47.42) −5.12(−5.55,−4.68)
Meningitis Republic of Croatia 377.79(290.55,489.11) 28.48(21.90,36.87) 114.38(87.83,146.31) 14.20(10.90,18.16) −2.25925 1628.40(1501.73,1750.29) 122.76(113.22,131.95) 153.30(123.32,183.07) 19.03(15.31,22.72) −5.23(−5.72,−4.74)
Meningitis Republic of Cuba 3983.87(3302.77,4737.94) 109.09(90.44,129.73) 1173.71(880.37,1520.91) 48.88(36.66,63.34) −2.56463 21,928.26(20883.68,23056.04) 600.44(571.84,631.32) 1427.66(1218.10,1692.42) 59.46(50.73,70.48) −6.69(−7.46,−5.93)
Meningitis Republic of Cyprus 23.65(18.56,29.38) 9.13(7.16,11.34) 4.50(3.35,6.00) 1.58(1.18,2.10) −5.68045 283.56(214.08,383.63) 109.46(82.64,148.08) 26.52(20.29,34.90) 9.30(7.12,12.24) −7.61(−7.87,−7.34)
Meningitis Republic of C么te d’Ivoire 17,774.01(14593.72,21326.72) 256.91(210.94,308.26) 13,223.35(11124.83,15564.35) 91.93(77.34,108.20) −3.14802 212,520.28(156138.20,284762.95) 3071.77(2256.82,4115.96) 127,931.55(75496.21,197797.84) 889.36(524.84,1375.06) −3.50(−4.10,−2.90)
Meningitis Republic of Djibouti 476.39(386.33,572.29) 212.41(172.26,255.17) 503.19(422.33,590.49) 95.23(79.93,111.76) −2.94964 5202.01(3809.37,6776.77) 2319.49(1698.54,3021.66) 3310.04(2374.12,4563.79) 626.46(449.33,863.75) −4.27(−4.97,−3.57)
Meningitis Republic of Ecuador 1475.95(1246.09,1727.24) 29.77(25.14,34.84) 543.75(432.06,693.93) 8.22(6.53,10.49) −4.93877 13,953.10(12878.70,15103.84) 281.45(259.78,304.66) 2724.41(2146.35,3465.09) 41.18(32.44,52.37) −6.48(−7.13,−5.82)
Meningitis Republic of El Salvador 1197.05(985.89,1438.75) 43.44(35.78,52.22) 246.16(185.18,328.73) 10.33(7.77,13.80) −5.09514 13,105.36(10592.67,15873.06) 475.63(384.43,576.07) 951.05(723.24,1296.89) 39.93(30.36,54.44) −8.20(−8.67,−7.72)
Meningitis Republic of Equatorial Guinea 725.95(602.45,860.36) 302.51(251.04,358.51) 606.18(505.10,723.31) 78.71(65.59,93.92) −4.78286 7718.55(5923.62,10856.98) 3216.33(2468.38,4524.11) 4068.01(2292.93,6436.14) 528.22(297.73,835.72) −6.45(−6.78,−6.11)
Meningitis Republic of Estonia 266.70(215.48,329.90) 58.06(46.91,71.82) 64.98(46.95,88.21) 23.18(16.75,31.47) −2.82103 1063.66(963.47,1164.97) 231.57(209.76,253.63) 77.81(66.51,91.90) 27.76(23.73,32.78) −6.22(−6.48,−5.96)
Meningitis Republic of Fiji 300.94(244.73,361.87) 83.90(68.22,100.88) 124.90(97.21,154.13) 35.62(27.72,43.96) −3.0512 1630.39(1226.94,2197.76) 454.52(342.05,612.69) 607.67(418.96,867.18) 173.31(119.49,247.32) −3.40(−3.88,−2.91)
Meningitis Republic of Finland 270.72(200.21,361.35) 21.34(15.78,28.48) 101.27(72.14,141.64) 8.82(6.28,12.33) −2.95826 1158.67(1072.12,1262.36) 91.32(84.50,99.49) 254.61(223.51,287.28) 22.17(19.46,25.01) −4.75(−4.99,−4.50)
Meningitis Republic of Ghana 24,082.57(19765.04,29455.70) 291.57(239.30,356.62) 16,132.01(13594.54,18962.62) 98.88(83.33,116.24) −3.99001 259,896.06(183943.39,365239.75) 3146.59(2227.03,4422.00) 111,121.88(71351.43,166443.19) 681.14(437.36,1020.25) −4.71(−5.10,−4.31)
Meningitis Republic of Guatemala 2024.02(1681.13,2380.36) 41.22(34.23,48.47) 1042.76(827.21,1318.35) 15.76(12.51,19.93) −3.34844 22,689.73(20609.20,25265.62) 462.04(419.67,514.49) 5646.00(4569.45,7073.24) 85.35(69.08,106.93) −5.72(−6.05,−5.39)
Meningitis Republic of Guinea 19,210.93(15692.65,23157.98) 584.42(477.39,704.49) 17,854.47(15492.85,20632.89) 239.19(207.56,276.42) −2.76312 222,274.39(168304.05,288492.63) 6761.85(5120.01,8776.29) 139,316.75(83211.37,234104.03) 1866.40(1114.77,3136.25) −3.66(−3.98,−3.34)
Meningitis Republic of Guinea−Bissau 3258.12(2681.78,3929.05) 554.01(456.01,668.10) 1586.13(1337.54,1856.53) 141.81(119.58,165.98) −4.73027 35,363.22(25738.25,47098.26) 6013.17(4376.54,8008.60) 10,404.56(7174.92,16625.55) 930.20(641.46,1486.38) −5.85(−6.63,−5.06)
Meningitis Republic of Guyana 224.24(186.84,265.90) 58.76(48.96,69.68) 62.63(48.32,80.48) 22.31(17.21,28.67) −3.61625 1688.64(1367.64,2051.06) 442.53(358.41,537.51) 183.82(137.62,247.35) 65.48(49.02,88.11) −5.94(−6.26,−5.61)
Meningitis Republic of Haiti 10,134.17(8330.19,12063.56) 302.84(248.93,360.49) 6134.55(5234.75,7181.81) 109.39(93.35,128.07) −2.87559 120,866.12(91071.81,158718.67) 3611.80(2721.47,4742.93) 57,025.71(38552.22,83688.17) 1016.91(687.48,1492.37) −3.58(−3.78,−3.37)
Meningitis Republic of Honduras 980.54(786.93,1177.86) 36.13(29.00,43.41) 663.41(535.56,832.84) 15.25(12.31,19.14) −2.30773 11,276.56(8972.47,14335.26) 415.56(330.65,528.28) 3794.74(1566.36,6248.04) 87.23(36.00,143.62) −4.32(−4.83,−3.82)
Meningitis Republic of Iceland 9.55(7.44,12.26) 11.30(8.81,14.50) 2.58(1.89,3.48) 2.89(2.12,3.90) −4.58285 105.41(92.17,118.92) 124.72(109.07,140.71) 23.18(19.10,28.01) 26.01(21.43,31.43) −5.23(−5.37,−5.08)
Meningitis Republic of India 657,645.99(532369.62,808803.29) 160.24(129.71,197.07) 238,194.60(194896.71,289179.17) 47.58(38.93,57.77) −4.05033 4,853,092.55(3903298.27,6281521.50) 1182.48(951.06,1530.52) 1,177,564.38(901586.86,1525609.20) 235.24(180.11,304.77) −4.73(−5.19,−4.27)
Meningitis Republic of Indonesia 135,325.95(104844.78,169408.61) 154.72(119.87,193.69) 33,905.73(26615.64,41491.47) 37.58(29.50,45.99) −4.58531 1,371,812.53(992126.33,1706187.50) 1568.44(1134.33,1950.75) 364,253.88(275786.73,469864.72) 403.75(305.69,520.81) −4.13(−4.40,−3.86)
Meningitis Republic of Iraq 7123.89(5905.28,8476.61) 69.17(57.34,82.31) 3748.17(2918.90,4782.10) 21.25(16.55,27.11) −3.84497 63,533.31(49511.21,80150.45) 616.92(480.76,778.27) 16,639.45(12248.86,22202.22) 94.34(69.45,125.88) −5.49(−6.11,−4.86)
Meningitis Republic of Italy 2852.24(1886.59,4151.82) 20.94(13.85,30.48) 496.78(378.82,651.80) 4.74(3.61,6.22) −5.70195 5594.65(5317.81,5888.30) 41.08(39.05,43.23) 1143.27(981.22,1301.73) 10.91(9.36,12.42) −4.34(−4.62,−4.06)
Meningitis Republic of Kazakhstan 4967.28(4108.63,6081.60) 74.77(61.85,91.55) 1917.54(1470.84,2484.12) 28.52(21.87,36.94) −3.39058 27,566.78(24247.11,31284.45) 414.97(365.00,470.93) 3235.08(2607.69,4028.49) 48.11(38.78,59.91) −6.72(−7.31,−6.13)
Meningitis Republic of Kenya 28,885.89(23341.11,35092.72) 209.44(169.24,254.45) 15,563.74(12876.13,18521.30) 63.27(52.34,75.29) −3.73373 283,547.58(225524.73,359368.05) 2055.91(1635.21,2605.66) 108,796.54(88103.80,140750.45) 442.25(358.14,572.15) −4.63(−5.06,−4.20)
Meningitis Republic of Kiribati 116.56(96.29,138.59) 318.01(262.71,378.12) 53.08(44.40,63.14) 99.32(83.07,118.14) −3.85302 1250.06(928.23,1621.48) 3410.52(2532.47,4423.86) 485.20(343.90,685.90) 907.86(643.46,1283.37) −4.23(−4.45,−4.01)
Meningitis Republic of Korea 1699.32(1344.67,2193.38) 10.67(8.44,13.77) 464.37(324.00,653.63) 5.54(3.86,7.80) −1.68899 15,768.46(12862.79,18546.96) 99.00(80.76,116.45) 428.57(350.51,547.87) 5.11(4.18,6.54) −8.95(−9.30,−8.59)
Meningitis Republic of Latvia 441.54(352.12,530.84) 58.68(46.80,70.55) 64.09(47.66,85.08) 16.56(12.31,21.98) −4.47715 1987.44(1845.18,2124.59) 264.14(245.23,282.37) 128.23(110.37,149.76) 33.13(28.51,38.69) −6.03(−6.44,−5.63)
Meningitis Republic of Liberia 8830.27(7065.67,10946.73) 646.35(517.19,801.27) 2231.52(1889.81,2619.99) 79.98(67.73,93.91) −6.75128 106,913.90(75034.59,152660.04) 7825.84(5492.35,11174.34) 22,494.43(12955.31,49161.79) 806.24(464.34,1762.05) −7.07(−7.37,−6.78)
Meningitis Republic of Lithuania 639.74(511.47,789.77) 57.76(46.18,71.30) 97.99(72.45,129.08) 18.29(13.52,24.09) −2.98873 2224.88(2051.36,2419.02) 200.87(185.20,218.40) 189.74(162.54,221.36) 35.41(30.34,41.31) −5.20(−5.70,−4.71)
Meningitis Republic of Madagascar 19,335.66(15955.05,23335.22) 287.48(237.22,346.94) 12,798.40(11001.56,14939.95) 85.64(73.62,99.97) −3.87387 224,936.58(171727.72,284658.68) 3344.29(2553.20,4232.22) 122,698.44(87883.50,168310.44) 821.07(588.09,1126.29) −4.33(−4.74,−3.92)
Meningitis Republic of Malawi 38,080.15(31409.50,45299.28) 683.26(563.57,812.79) 11,977.65(10303.43,13872.39) 113.09(97.29,130.98) −6.06443 460,071.88(319329.42,639807.97) 8254.94(5729.64,11479.90) 113,407.80(72007.52,167990.92) 1070.81(679.90,1586.19) −6.67(−6.96,−6.38)
Meningitis Republic of Maldives 50.32(40.26,61.03) 39.21(31.37,47.55) 22.80(17.12,30.92) 17.50(13.14,23.73) −2.39112 476.19(359.72,626.66) 371.03(280.28,488.27) 55.39(41.00,75.17) 42.51(31.46,57.69) −6.22(−6.67,−5.78)
Meningitis Republic of Mali 29,088.34(23660.86,35486.47) 588.13(478.40,717.50) 21,212.82(17570.22,24768.97) 149.04(123.45,174.02) −4.92435 349,584.57(250722.58,471276.34) 7068.22(5069.34,9528.70) 172,964.92(126830.85,233044.68) 1215.23(891.10,1637.35) −5.91(−6.59,−5.23)
Meningitis Republic of Malta 14.23(11.29,17.98) 12.34(9.80,15.60) 3.62(2.82,4.60) 4.31(3.35,5.48) −4.93357 100.42(86.50,114.44) 87.13(75.05,99.29) 23.47(18.47,28.85) 27.95(22.00,34.37) −4.73(−6.06,−3.38)
Meningitis Republic of Mauritius 156.62(126.81,190.48) 36.36(29.43,44.21) 46.22(35.58,60.00) 15.57(11.98,20.21) −2.98723 567.06(520.86,623.54) 131.63(120.90,144.73) 192.65(161.35,226.47) 64.89(54.34,76.28) 2.70(1.25,4.18)
Meningitis Republic of Moldova 1291.08(1078.25,1545.11) 81.65(68.19,97.71) 129.55(100.58,162.89) 18.61(14.45,23.40) −4.02066 9024.49(8053.68,10136.32) 570.71(509.31,641.02) 583.76(435.80,772.38) 83.84(62.59,110.94) −4.41(−5.14,−3.67)
Meningitis Republic of Mozambique 31,569.05(25941.90,37820.63) 416.99(342.66,499.57) 20,410.14(17209.41,23850.14) 114.96(96.93,134.34) −4.38802 357,800.70(274262.52,466085.66) 4726.12(3622.68,6156.44) 109,066.78(75302.84,171613.97) 614.32(424.14,966.61) −6.47(−7.10,−5.83)
Meningitis Republic of Namibia 659.70(547.69,790.52) 86.61(71.91,103.79) 426.84(361.39,510.89) 39.84(33.73,47.68) −2.97692 6277.85(4634.24,8154.75) 824.21(608.42,1070.63) 3576.78(2593.55,5075.30) 333.85(242.07,473.71) −3.00(−3.91,−2.08)
Meningitis Republic of Nauru 4.63(3.75,5.63) 88.77(71.88,108.14) 2.54(2.06,3.08) 49.57(40.22,60.05) −2.35628 28.72(20.94,37.42) 551.19(401.96,718.25) 13.91(9.84,18.93) 271.10(191.93,369.02) −2.62(−3.57,−1.65)
Meningitis Republic of Nicaragua 1776.35(1482.27,2148.70) 78.94(65.87,95.49) 291.51(226.89,375.14) 11.22(8.73,14.43) −6.67741 20,003.80(16521.13,24543.73) 888.95(734.19,1090.70) 1657.56(1178.66,2372.44) 63.77(45.35,91.27) −8.53(−8.77,−8.28)
Meningitis Republic of Niue 0.71(0.55,0.89) 69.71(53.75,87.17) 0.20(0.16,0.26) 38.00(29.57,49.31) −2.95369 3.12(2.36,4.06) 304.98(231.27,397.00) 1.96(1.53,2.57) 371.12(290.01,487.07) −2.55(−3.61,−1.48)
Meningitis Republic of Palau 4.83(3.90,5.96) 78.37(63.20,96.60) 1.27(0.96,1.66) 28.61(21.64,37.50) −3.54004 20.89(14.68,27.64) 338.83(238.16,448.30) 3.66(2.76,4.84) 82.73(62.29,109.31) −4.45(−4.76,−4.14)
Meningitis Republic of Panama 427.44(342.89,513.82) 39.32(31.54,47.27) 209.13(163.53,263.68) 13.87(10.85,17.49) −3.41167 4543.72(3914.08,5217.79) 417.99(360.07,480.00) 1381.31(1086.38,1762.62) 91.65(72.08,116.94) −4.79(−5.05,−4.53)
Meningitis Republic of Paraguay 1180.44(979.31,1419.61) 57.05(47.33,68.61) 364.90(281.69,467.86) 13.66(10.55,17.52) −5.01821 10,990.36(8809.10,13416.74) 531.17(425.75,648.43) 2640.56(1832.07,3801.40) 98.87(68.60,142.34) −5.63(−5.98,−5.28)
Meningitis Republic of Peru 3427.11(2800.50,4093.38) 32.18(26.30,38.44) 1158.99(895.88,1500.33) 9.26(7.16,11.99) −4.26652 38,088.44(31988.76,45271.09) 357.65(300.37,425.09) 4445.03(3178.27,6074.29) 35.53(25.40,48.55) −7.45(−7.76,−7.14)
Meningitis Republic of Poland 3776.55(2669.11,5074.96) 30.33(21.44,40.76) 271.47(215.41,338.89) 3.53(2.80,4.40) −6.83923 23,214.99(21757.70,24594.81) 186.47(174.77,197.56) 1078.91(862.54,1350.64) 14.01(11.20,17.54) −6.37(−7.39,−5.34)
Meningitis Republic of Rwanda 17,675.74(14422.56,21420.54) 427.09(348.48,517.57) 4916.63(4132.69,5730.06) 76.37(64.19,89.00) −6.80136 212,303.30(142259.20,305191.01) 5129.74(3437.31,7374.12) 40,322.88(27956.59,60304.76) 626.32(434.24,936.69) −7.89(−8.56,−7.22)
Meningitis Republic of San Marino 0.77(0.57,1.02) 12.90(9.53,17.13) 0.25(0.19,0.35) 4.07(3.00,5.59) −3.62384 4.73(3.19,6.88) 79.12(53.27,114.95) 0.53(0.35,0.80) 8.49(5.59,12.81) −6.68(−6.93,−6.43)
Meningitis Republic of Senegal 18,055.76(14522.44,21946.88) 406.03(326.57,493.53) 9081.81(7712.95,10729.38) 111.91(95.04,132.21) −4.7143 188,708.49(145454.48,249230.40) 4243.56(3270.89,5604.53) 52,938.10(38398.76,81252.84) 652.32(473.16,1001.23) −6.04(−6.71,−5.37)
Meningitis Republic of Serbia 716.34(560.55,898.60) 24.69(19.32,30.97) 152.42(112.35,206.32) 8.13(6.00,11.01) −4.53628 4042.69(3097.66,5137.19) 139.35(106.78,177.08) 175.04(139.94,223.39) 9.34(7.47,11.92) −8.78(−9.40,−8.16)
Meningitis Republic of Seychelles 27.87(23.50,32.48) 89.22(75.21,103.97) 6.17(4.82,7.74) 20.21(15.79,25.36) −4.81062 324.40(296.62,354.60) 1038.35(949.42,1135.01) 36.38(26.64,50.08) 119.17(87.26,164.03) −4.53(−6.59,−2.43)
Meningitis Republic of Sierra Leone 14,617.04(11773.78,17818.75) 662.69(533.79,807.85) 6092.50(5057.10,7021.06) 133.88(111.13,154.29) −5.86594 176,801.86(113903.89,253753.58) 8015.66(5164.06,11504.42) 48,834.42(34314.95,69156.43) 1073.13(754.06,1519.70) −7.09(−7.62,−6.55)
Meningitis Republic of Singapore 69.90(56.70,87.94) 7.59(6.16,9.55) 28.80(22.67,37.10) 2.76(2.17,3.56) −2.76152 719.96(655.23,781.38) 78.17(71.15,84.84) 87.10(74.04,101.93) 8.35(7.10,9.77) −6.71(−7.47,−5.96)
Meningitis Republic of Slovenia 155.96(114.01,206.84) 28.01(20.48,37.15) 55.17(39.37,77.21) 13.63(9.72,19.07) −1.4343 438.55(393.56,484.04) 78.77(70.69,86.94) 39.30(32.91,45.95) 9.71(8.13,11.35) −5.71(−6.02,−5.41)
Meningitis Republic of South Africa 16,503.51(13433.24,20140.27) 93.65(76.23,114.29) 9111.10(7312.16,11108.54) 45.74(36.71,55.77) −2.29879 148,762.09(112518.48,183526.21) 844.20(638.52,1041.48) 64,451.53(51720.30,78193.74) 323.58(259.67,392.58) −2.71(−3.08,−2.35)
Meningitis Republic of South Sudan 15,484.71(12792.73,18187.01) 471.22(389.30,553.46) 16,619.49(14116.23,19369.08) 302.87(257.25,352.98) −1.27857 151,926.03(99078.24,200671.05) 4623.34(3015.10,6106.72) 146,847.60(101383.52,200554.27) 2676.11(1847.59,3654.85) −1.36(−1.65,−1.06)
Meningitis Republic of Sudan 16,278.29(13163.40,19359.97) 147.37(119.17,175.26) 6704.02(5394.21,8286.83) 31.36(25.24,38.77) −5.01396 182,885.44(144579.47,239674.68) 1655.65(1308.87,2169.76) 26,703.68(17633.61,40861.30) 124.93(82.50,191.16) −7.44(−8.41,−6.46)
Meningitis Republic of Suriname 139.34(117.34,164.16) 81.49(68.62,96.01) 67.32(53.92,83.25) 35.46(28.40,43.85) −2.87942 1285.78(867.78,1633.74) 751.96(507.50,955.46) 320.25(217.84,478.62) 168.68(114.74,252.10) −5.11(−5.52,−4.71)
Meningitis Republic of Tajikistan 4109.44(3454.77,4786.78) 142.96(120.19,166.53) 2553.27(2107.91,3021.90) 57.31(47.31,67.83) −3.22057 39,714.79(33234.11,46730.24) 1381.63(1156.18,1625.69) 13,465.51(8348.07,20593.49) 302.25(187.38,462.24) −4.99(−5.30,−4.69)
Meningitis Republic of the Congo 2776.76(2336.38,3268.62) 209.30(176.11,246.38) 1798.47(1508.18,2131.94) 72.32(60.65,85.73) −3.81825 26,449.50(20458.64,34389.19) 1993.65(1542.09,2592.11) 11,838.85(8411.39,16325.30) 476.06(338.24,656.47) −4.93(−5.72,−4.14)
Meningitis Republic of the Gambia 1844.68(1527.70,2221.80) 328.36(271.93,395.49) 1379.03(1150.42,1631.09) 108.88(90.83,128.78) −3.9859 17,768.31(13260.28,23206.95) 3162.79(2360.36,4130.88) 9068.39(6270.51,13653.74) 715.95(495.06,1077.97) −4.90(−5.39,−4.40)
Meningitis Republic of the Marshall Islands 20.08(16.07,24.65) 74.98(60.02,92.03) 8.05(6.38,10.00) 34.88(27.64,43.33) −2.75329 96.58(73.18,149.79) 360.61(273.23,559.28) 33.98(23.54,49.86) 147.27(102.05,216.09) −3.07(−3.56,−2.58)
Meningitis Republic of the Niger 61,073.01(48788.03,76771.29) 1258.82(1005.61,1582.39) 31,304.61(26067.20,37967.09) 200.84(167.24,243.59) −6.63768 736,141.26(528892.09,1027350.32) 15,173.18(10901.41,21175.52) 329,414.14(210339.21,545878.74) 2113.42(1349.47,3502.19) −6.92(−7.42,−6.41)
Meningitis Republic of the Philippines 26,429.16(20927.53,32329.25) 82.46(65.29,100.86) 10,899.26(8895.30,13199.54) 24.34(19.87,29.48) −3.57115 296,118.93(216383.92,356088.44) 923.85(675.09,1110.95) 104,242.23(83221.57,133897.24) 232.80(185.85,299.03) −3.64(−4.01,−3.27)
Meningitis Republic of the Union of Myanmar 46,938.39(37578.47,58560.63) 245.61(196.63,306.42) 8735.12(7263.93,10249.26) 42.06(34.98,49.35) −5.42149 566,198.68(402495.18,784250.12) 2962.65(2106.06,4103.60) 99,158.48(66904.63,144202.58) 477.45(322.15,694.34) −5.56(−6.17,−4.95)
Meningitis Republic of Trinidad and Tobago 264.33(215.11,321.38) 50.89(41.41,61.87) 86.00(65.60,113.56) 23.63(18.02,31.20) −2.48305 1892.79(1608.03,2175.93) 364.37(309.55,418.87) 233.39(167.24,336.11) 64.12(45.95,92.34) −5.62(−5.98,−5.26)
Meningitis Republic of Tunisia 1784.21(1406.18,2185.04) 44.72(35.24,54.76) 623.43(468.78,823.48) 17.39(13.07,22.97) −2.59539 12,383.65(8628.05,18250.25) 310.36(216.24,457.39) 1045.06(700.85,1517.03) 29.15(19.55,42.31) −6.48(−6.94,−6.02)
Meningitis Republic of Turkey 11,358.88(9026.88,13835.39) 42.57(33.83,51.85) 1416.36(1067.77,1844.06) 5.73(4.32,7.46) −7.16161 120,188.63(84063.08,168449.12) 450.45(315.06,631.33) 6508.37(5106.34,8163.51) 26.34(20.66,33.03) −9.22(−9.67,−8.77)
Meningitis Republic of Uganda 40,078.89(32631.37,47702.30) 389.20(316.88,463.23) 26,595.55(22545.14,30998.36) 106.62(90.38,124.27) −4.3241 486,305.35(311476.58,752828.84) 4722.43(3024.69,7310.59) 237,810.16(145889.06,371487.94) 953.39(584.88,1489.32) −5.11(−5.45,−4.78)
Meningitis Republic of Uzbekistan 10,021.64(8341.95,11763.45) 93.87(78.14,110.19) 3267.26(2462.09,4302.98) 25.91(19.52,34.12) −4.51218 78,175.93(69301.74,88147.43) 732.27(649.15,825.67) 6379.93(5313.58,7617.37) 50.59(42.14,60.41) −8.74(−9.28,−8.20)
Meningitis Republic of Vanuatu 64.65(52.86,78.64) 77.47(63.35,94.24) 68.34(55.60,84.25) 46.35(37.71,57.14) −1.88879 362.27(258.18,557.39) 434.12(309.39,667.95) 265.85(183.83,429.31) 180.32(124.68,291.18) −2.91(−3.57,−2.24)
Meningitis Republic of Yemen 6949.42(5720.79,8307.04) 82.65(68.04,98.80) 4460.96(3504.81,5560.23) 25.53(20.06,31.82) −3.99089 72,206.83(48868.79,106806.39) 858.78(581.21,1270.28) 21,674.45(13723.80,39390.23) 124.05(78.55,225.45) −6.30(−6.72,−5.87)
Meningitis Republic of Zambia 27,271.82(22294.32,32750.62) 580.19(474.30,696.75) 9947.36(8461.29,11762.77) 95.15(80.94,112.52) −5.79805 327,908.60(243164.22,429818.89) 6976.05(5173.17,9144.13) 85,301.78(54285.02,122792.99) 815.95(519.26,1174.58) −6.63(−7.13,−6.12)
Meningitis Republic of Zimbabwe 6417.67(5232.89,7626.42) 106.56(86.89,126.63) 5940.09(5084.31,6917.77) 74.40(63.68,86.64) −0.98051 55,768.81(44582.38,69746.94) 926.03(740.28,1158.13) 49,145.56(35064.20,70727.94) 615.53(439.17,885.84) −0.94(−1.61,−0.28)
Meningitis Romania 3262.90(2673.20,3986.94) 43.49(35.63,53.14) 396.95(305.15,520.45) 9.82(7.55,12.88) −4.16324 28,731.57(26388.32,31197.76) 382.94(351.71,415.81) 1029.73(859.50,1299.19) 25.48(21.27,32.15) −7.51(−7.89,−7.12)
Meningitis Russian Federation 29,515.39(23152.35,36224.72) 65.32(51.24,80.17) 5754.08(4352.34,7450.25) 17.03(12.88,22.05) −3.76991 112,886.84(109399.58,116698.67) 249.83(242.11,258.27) 14,125.44(12807.27,15551.77) 41.80(37.90,46.03) −4.45(−5.01,−3.89)
Meningitis Saint Kitts and Nevis 13.25(11.09,15.73) 72.13(60.37,85.63) 4.30(3.31,5.45) 30.56(23.53,38.79) −3.01364 83.47(74.22,93.78) 454.33(403.99,510.46) 11.55(9.24,14.31) 82.12(65.69,101.79) −5.72(−6.20,−5.23)
Meningitis Saint Lucia 41.80(34.22,49.61) 62.60(51.25,74.29) 12.84(9.88,16.30) 30.61(23.54,38.85) −2.56288 237.28(200.04,279.41) 355.34(299.57,418.43) 24.16(18.51,31.32) 57.59(44.12,74.65) −6.27(−6.68,−5.86)
Meningitis Saint Vincent and the Grenadines 37.28(31.37,44.51) 69.36(58.36,82.80) 10.22(7.95,13.07) 30.31(23.59,38.79) −3.0117 253.34(210.86,302.95) 471.31(392.28,563.59) 22.73(18.37,28.45) 67.43(54.49,84.42) −6.56(−6.94,−6.17)
Meningitis Slovak Republic 543.05(417.65,700.91) 30.94(23.79,39.93) 143.78(106.76,191.20) 12.82(9.52,17.05) −3.20428 1784.99(1519.85,2092.67) 101.70(86.59,119.23) 251.82(191.28,337.79) 22.46(17.06,30.13) −4.67(−4.95,−4.39)
Meningitis Socialist Republic of Viet Nam 16,409.69(12809.84,20180.16) 48.74(38.05,59.94) 4043.83(3295.31,4836.20) 12.79(10.42,15.30) −4.18039 190,039.59(133925.98,273952.20) 564.47(397.80,813.71) 33,138.66(21444.58,51742.07) 104.81(67.82,163.64) −5.03(−5.28,−4.79)
Meningitis Solomon Islands 159.73(128.18,195.49) 82.07(65.86,100.45) 108.48(85.48,136.79) 32.80(25.84,41.36) −3.22755 1070.68(713.70,1563.64) 550.15(366.72,803.45) 446.98(335.43,601.87) 135.15(101.42,181.98) −4.27(−4.88,−3.65)
Meningitis State of Eritrea 5892.07(4906.21,7050.13) 299.58(249.45,358.46) 3017.14(2522.47,3538.92) 93.80(78.42,110.02) −3.75093 65,669.71(48592.38,87704.39) 3338.93(2470.65,4459.27) 27,924.12(18040.01,42260.07) 868.11(560.83,1313.79) −4.04(−4.46,−3.61)
Meningitis State of Israel 209.16(164.89,263.59) 10.43(8.22,13.14) 68.57(51.62,88.35) 2.03(1.53,2.62) −5.12668 2478.67(2276.94,2660.22) 123.54(113.49,132.59) 575.71(498.04,654.92) 17.07(14.76,19.41) −5.67(−5.94,−5.39)
Meningitis State of Kuwait 226.93(171.53,291.37) 33.08(25.01,42.48) 182.75(133.75,241.10) 16.68(12.21,22.01) −2.58794 736.29(663.84,831.68) 107.34(96.78,121.24) 270.18(226.87,321.79) 24.66(20.71,29.37) −3.25(−3.95,−2.55)
Meningitis State of Libya 767.42(605.49,952.85) 33.25(26.23,41.28) 247.67(185.48,330.84) 11.86(8.88,15.85) −3.54362 4376.80(2955.54,6548.16) 189.61(128.04,283.68) 1093.61(720.81,1558.87) 52.39(34.53,74.68) −3.47(−3.66,−3.28)
Meningitis State of Qatar 57.69(43.74,74.29) 37.68(28.57,48.53) 103.69(75.40,139.78) 17.37(12.63,23.41) −2.89901 153.51(102.60,243.47) 100.28(67.02,159.05) 105.33(81.08,132.91) 17.64(13.58,22.26) −4.90(−5.29,−4.50)
Meningitis Sultanate of Oman 410.46(321.95,519.12) 40.95(32.12,51.79) 338.68(245.72,458.33) 22.70(16.47,30.72) −2.45197 1910.59(1415.27,2588.11) 190.62(141.20,258.22) 356.08(275.85,450.07) 23.87(18.49,30.17) −5.78(−6.66,−4.89)
Meningitis Swiss Confederation 421.36(318.07,536.68) 26.72(20.17,34.03) 141.94(102.83,190.38) 8.05(5.83,10.80) −3.87045 3233.93(3015.18,3505.20) 205.05(191.18,222.25) 614.48(519.29,720.18) 34.86(29.46,40.86) −5.83(−6.17,−5.49)
Meningitis Syrian Arab Republic 6192.14(5117.86,7409.83) 84.22(69.61,100.79) 1487.37(1140.42,1856.31) 27.34(20.96,34.12) −3.65554 64,334.54(48873.70,84210.13) 875.07(664.77,1145.42) 7004.13(5278.88,8895.38) 128.75(97.04,163.51) −5.70(−6.40,−4.98)
Meningitis Taiwan (Province of China) 2861.32(2098.33,3841.06) 39.15(28.71,52.55) 824.04(578.18,1163.13) 20.37(14.29,28.75) −2.93549 8386.04(7885.82,8901.59) 114.74(107.89,121.79) 954.19(841.50,1072.27) 23.59(20.80,26.51) −5.54(−6.32,−4.75)
Meningitis Togolese Republic 6803.91(5666.83,8234.76) 316.06(263.24,382.53) 4214.15(3576.31,4995.00) 100.93(85.65,119.63) −4.05677 63,484.77(49871.12,80920.10) 2949.04(2316.65,3758.96) 28,934.65(16832.68,49341.09) 692.98(403.14,1181.71) −4.63(−5.36,−3.88)
Meningitis Tokelau 0.60(0.47,0.74) 78.90(61.87,97.52) 0.34(0.26,0.44) 67.32(51.14,86.14) −1.60685 3.05(2.23,4.06) 402.17(293.98,534.67) 3.44(2.59,4.54) 671.70(506.46,887.56) −2.30(−3.85,−0.73)
Meningitis Turkmenistan 1926.42(1605.35,2246.54) 102.18(85.15,119.17) 663.72(527.54,828.78) 33.85(26.91,42.27) −3.76386 13,942.75(12323.37,15759.86) 739.58(653.68,835.96) 1430.46(1134.63,1859.14) 72.96(57.87,94.83) −7.04(−7.78,−6.30)
Meningitis Tuvalu 5.90(4.84,7.20) 138.08(113.25,168.45) 1.79(1.41,2.29) 36.51(28.64,46.55) −4.51216 50.77(37.24,66.95) 1188.02(871.45,1566.86) 7.87(5.56,11.61) 160.11(113.17,236.31) −6.30(−6.51,−6.09)
Meningitis Ukraine 10,407.04(8046.34,13061.08) 69.14(53.46,86.77) 1964.73(1473.90,2642.59) 23.26(17.45,31.29) −3.11045 40,578.96(35274.23,46081.90) 269.60(234.35,306.16) 4475.73(3743.05,5167.94) 53.00(44.32,61.19) −4.24(−4.64,−3.83)
Meningitis Union of the Comoros 700.04(580.46,837.15) 264.85(219.61,316.72) 312.43(264.47,367.70) 99.52(84.24,117.12) −3.34381 8119.95(5972.77,10574.15) 3072.04(2259.69,4000.55) 2824.04(2106.41,3658.89) 899.53(670.94,1165.45) −4.01(−4.34,−3.68)
Meningitis United Arab Emirates 288.80(225.90,361.92) 40.85(31.95,51.19) 234.29(170.77,326.10) 13.82(10.07,19.24) −3.69843 2385.94(1806.74,3062.11) 337.46(255.54,433.10) 493.20(377.98,633.22) 29.10(22.30,37.36) −6.45(−6.92,−5.99)
Meningitis United Kingdom of Great Britain and Northern Ireland 5525.93(3964.70,7401.73) 37.25(26.73,49.90) 2083.56(1540.09,2780.68) 13.31(9.84,17.76) −3.98261 25,080.39(24217.37,26000.99) 169.07(163.26,175.28) 4502.89(4110.85,4870.30) 28.76(26.26,31.11) −5.87(−6.24,−5.49)
Meningitis United Mexican States 14,322.68(10993.62,18179.74) 33.03(25.35,41.92) 2620.33(1965.22,3515.74) 6.07(4.55,8.15) −5.67034 124,911.26(113559.17,139441.26) 288.03(261.86,321.54) 11,745.59(9439.10,14703.42) 27.22(21.87,34.07) −7.65(−8.36,−6.94)
Meningitis United Republic of Tanzania 45,210.49(37390.44,54353.51) 302.95(250.55,364.22) 26,793.48(22640.14,31173.12) 86.83(73.37,101.02) −4.04309 538,036.37(348420.23,773489.11) 3605.36(2334.75,5183.12) 202,530.88(114186.19,318668.98) 656.33(370.03,1032.69) −5.08(−5.65,−4.51)
Meningitis United States of America 16,962.64(11867.83,23380.18) 22.91(16.03,31.58) 2919.60(2238.15,3801.23) 3.59(2.75,4.67) −6.55199 66,085.45(63068.48,69711.65) 89.25(85.18,94.15) 11,397.45(10393.31,12534.73) 14.02(12.78,15.42) −5.97(−6.33,−5.61)
Meningitis United States Virgin Islands 18.30(14.02,23.50) 43.87(33.60,56.33) 5.67(4.13,7.91) 31.11(22.69,43.44) −1.03522 43.04(32.17,58.23) 103.18(77.11,139.59) 3.27(2.48,4.30) 17.97(13.62,23.58) −5.21(−5.61,−4.82)
Pertussis American Samoa 160.72(124.25,204.68) 671.73(519.30,855.45) 1.64(0.80,2.90) 8.57(4.19,15.18) −5.55(−7.55,−3.51) 70.36(7.31,202.49) 294.07(30.56,846.28) 20.08(2.32,56.60) 104.95(12.11,295.88) −3.23(−3.48,−2.98)
Pertussis Antigua and Barbuda 59.12(45.13,76.31) 247.47(188.89,319.41) 0.34(0.10,1.55) 1.45(0.42,6.63) −3.02(−6.16,0.22) 0.41(0.24,0.65) 1.73(1.02,2.73) 0.00(0.00,0.01) 0.01(0.00,0.05) −2.88(−5.85,0.17)
Pertussis Arab Republic of Egypt 362,038.70(279464.22,457518.45) 1296.57(1000.85,1638.51) 37,927.74(12185.36,85714.41) 81.48(26.18,184.13) −4.68(−6.04,−3.30) 222,412.56(20151.44,694527.65) 796.53(72.17,2487.32) 10,572.65(496.67,40456.11) 22.71(1.07,86.91) −7.02(−8.27,−5.75)
Pertussis Argentine Republic 124,166.52(95944.27,156626.34) 953.16(736.51,1202.34) 4857.95(1839.45,9783.97) 35.43(13.42,71.36) −4.79(−6.54,−3.00) 3958.07(2606.78,5687.71) 30.38(20.01,43.66) 78.56(21.45,201.00) 0.57(0.16,1.47) −5.79(−8.23,−3.29)
Pertussis Australia 18,722.25(14519.97,23992.34) 361.99(280.74,463.88) 166.54(41.21,378.64) 2.67(0.66,6.07) −4.58(−8.14,−0.89) 130.69(74.88,210.14) 2.53(1.45,4.06) 1.99(0.46,5.62) 0.03(0.01,0.09) −4.02(−7.36,−0.56)
Pertussis Barbados 614.39(475.28,775.80) 723.62(559.78,913.74) 1.12(0.33,5.12) 1.69(0.49,7.71) −5.44(−8.78,−1.99) 4.21(2.53,6.58) 4.96(2.97,7.75) 0.01(0.00,0.03) 0.01(0.00,0.05) −5.44(−8.77,−1.98)
Pertussis Belize 1209.02(933.20,1528.07) 1178.66(909.76,1489.69) 5.17(1.50,23.67) 3.06(0.89,14.00) −4.63(−8.04,−1.08) 9.31(5.95,14.18) 9.07(5.80,13.82) 0.04(0.01,0.16) 0.02(0.01,0.10) −5.48(−8.80,−2.03)
Pertussis Bermuda 41.36(31.51,53.61) 260.08(198.14,337.15) 0.04(0.01,0.18) 0.35(0.10,1.60) −6.82(−10.02,−3.51) 0.32(0.20,0.51) 2.01(1.25,3.19) 0.00(0.00,0.00) 0.00(0.00,0.01) −6.84(−10.09,−3.47)
Pertussis Bolivarian Republic of Venezuela 130,607.14(99871.27,165962.80) 1439.03(1100.38,1828.57) 10,421.58(5475.30,17317.19) 119.08(62.56,197.87) −3.01(−4.53,−1.47) 3488.31(2363.45,4859.04) 38.43(26.04,53.54) 240.19(89.58,544.90) 2.74(1.02,6.23) −4.86(−6.38,−3.31)
Pertussis Bosnia and Herzegovina 14,822.97(11419.25,18801.61) 1000.37(770.66,1268.87) 68.33(25.13,146.18) 10.27(3.78,21.98) −4.45(−7.17,−1.64) 4590.75(733.90,10728.42) 309.82(49.53,724.03) 33.69(2.09,121.62) 5.07(0.31,18.29) −6.54(−8.51,−4.54)
Pertussis Brunei Darussalam 668.79(517.29,852.25) 581.43(449.72,740.92) 0.23(0.04,1.06) 0.18(0.03,0.82) −7.46(−11.53,−3.20) 268.71(27.58,774.13) 233.61(23.98,673.01) 1.56(0.01,7.10) 1.20(0.01,5.50) −7.11(−9.24,−4.92)
Pertussis Burkina Faso 140,962.06(106918.26,179547.77) 2491.72(1889.94,3173.78) 28,747.57(18168.26,42218.47) 224.49(141.88,329.68) −7.06(−7.87,−6.24) 162,556.09(14400.15,495795.68) 2873.43(254.54,8763.95) 29,875.39(2459.11,97705.42) 233.30(19.20,762.98) −6.91(−7.67,−6.13)
Pertussis Canada 49,951.83(38652.42,63145.45) 651.71(504.29,823.85) 2578.80(585.42,6354.00) 31.34(7.11,77.22) −2.23(−4.36,−0.06) 347.57(210.29,541.54) 4.53(2.74,7.07) 18.99(3.82,49.65) 0.23(0.05,0.60) −2.07(−4.22,0.12)
Pertussis Central African Republic 35,119.12(26665.94,44769.46) 2345.74(1781.12,2990.33) 41,743.40(21181.29,73277.62) 1442.41(731.90,2532.05) −0.15(−0.63,0.34) 53,798.42(4434.72,186933.58) 3593.41(296.21,12486.03) 49,269.09(3925.47,166567.52) 1702.45(135.64,5755.60) −0.84(−1.29,−0.38)
Pertussis Commonwealth of Dominica 163.74(126.96,209.76) 499.63(387.38,640.06) 0.19(0.05,0.86) 0.97(0.28,4.40) −5.36(−8.56,−2.05) 85.69(8.58,250.50) 261.47(26.19,764.37) 0.67(0.05,2.56) 3.45(0.25,13.18) −3.98(−6.13,−1.79)
Pertussis Commonwealth of the Bahamas 616.68(477.16,779.93) 572.80(443.21,724.43) 2.00(0.58,9.11) 1.73(0.50,7.90) −5.80(−8.80,−2.71) 4.23(2.56,6.65) 3.93(2.38,6.18) 0.01(0.00,0.06) 0.01(0.00,0.05) −5.81(−8.81,−2.72)
Pertussis Cook Islands 55.53(42.97,70.21) 644.95(499.08,815.45) 0.34(0.17,0.61) 6.64(3.24,11.82) −6.92(−8.97,−4.82) 22.04(2.71,63.27) 255.97(31.51,734.85) 1.46(0.14,4.60) 28.27(2.63,88.79) −7.01(−7.61,−6.40)
Pertussis Czech Republic 4385.63(3301.10,5756.61) 144.08(108.45,189.12) 61.63(22.21,131.74) 2.78(1.00,5.93) −1.67(−4.30,1.03) 30.22(17.33,49.77) 0.99(0.57,1.64) 0.44(0.15,1.01) 0.02(0.01,0.05) −1.61(−4.23,1.07)
Pertussis Democratic People’s Republic of Korea 133,395.71(101163.44,170061.72) 1712.54(1298.74,2183.26) 421.27(212.76,756.81) 6.38(3.22,11.46) −13.12(−15.34,−10.85) 86,285.06(9426.35,238347.80) 1107.73(121.02,3059.92) 121.96(9.56,449.59) 1.85(0.14,6.81) −14.91(−17.21,−12.54)
Pertussis Democratic Republic of Sao Tome and Principe 904.79(696.22,1149.03) 1294.70(996.25,1644.20) 169.28(107.00,248.77) 166.28(105.10,244.37) −5.28(−6.11,−4.44) 1039.39(101.92,3081.13) 1487.31(145.84,4408.91) 105.48(9.05,322.48) 103.62(8.89,316.76) −6.85(−7.59,−6.10)
Pertussis Democratic Republic of the Congo 576,137.91(435554.21,731695.66) 2661.12(2011.78,3379.63) 605,612.34(307476.60,1058939.16) 1264.14(641.82,2210.41) −2.38(−2.84,−1.91) 638,871.72(59444.24,1983065.87) 2950.88(274.57,9159.58) 366,119.23(24089.93,1332914.23) 764.23(50.28,2782.29) −3.66(−4.14,−3.17)
Pertussis Democratic Republic of Timor−Leste 13,611.70(10237.63,17295.98) 3347.16(2517.47,4253.14) 397.63(192.37,691.84) 58.01(28.07,100.93) −6.10(−7.92,−4.24) 10,511.08(913.97,31397.30) 2584.71(224.75,7720.70) 476.30(42.51,1664.10) 69.49(6.20,242.78) −6.28(−7.72,−4.82)
Pertussis Democratic Socialist Republic of Sri Lanka 17,168.99(13084.69,22251.27) 237.14(180.72,307.33) 234.40(49.41,714.94) 3.40(0.72,10.36) −0.16(−3.32,3.10) 7690.24(812.41,23311.37) 106.22(11.22,321.98) 150.21(2.74,802.20) 2.18(0.04,11.63) −2.19(−4.61,0.30)
Pertussis Dominican Republic 50,494.79(38669.50,64256.61) 1441.83(1104.17,1834.78) 204.39(59.28,942.17) 5.25(1.52,24.22) −4.90(−8.10,−1.59) 37,651.84(4020.40,107562.11) 1075.11(114.80,3071.32) 385.41(36.86,1139.09) 9.91(0.95,29.28) −5.75(−8.01,−3.43)
Pertussis Eastern Republic of Uruguay 7888.17(6101.42,9966.79) 732.40(566.51,925.40) 164.48(75.30,293.41) 18.21(8.34,32.48) −5.08(−7.07,−3.05) 92.80(58.38,137.85) 8.62(5.42,12.80) 6.79(2.44,15.74) 0.75(0.27,1.74) −0.53(−2.88,1.89)
Pertussis Federal Democratic Republic of Ethiopia 903,497.90(681372.25,1147167.17) 3066.11(2312.30,3893.03) 480,177.58(307034.15,700503.64) 839.50(536.79,1224.70) −3.07(−3.78,−2.36) 1,358,092.38(108624.49,3901506.28) 4608.82(368.63,13240.15) 335,178.14(34704.46,985217.69) 586.00(60.67,1722.47) −5.32(−6.00,−4.63)
Pertussis Federal Democratic Republic of Nepal 270,775.97(204556.54,343719.61) 2616.49(1976.62,3321.34) 28,599.51(11398.93,55236.78) 229.63(91.52,443.51) −6.25(−7.25,−5.24) 242,961.87(24948.92,728597.95) 2347.73(241.08,7040.40) 14,152.49(1303.41,46486.22) 113.63(10.47,373.25) −7.56(−8.47,−6.63)
Pertussis Federal Republic of Germany 129,476.75(100179.46,163550.41) 747.11(578.06,943.72) 397.28(130.32,946.19) 2.49(0.82,5.93) −8.06(−10.63,−5.41) 1369.61(908.97,1978.73) 7.90(5.24,11.42) 4.58(1.72,9.53) 0.03(0.01,0.06) −8.08(−10.42,−5.68)
Pertussis Federal Republic of Nigeria 1,308,256.48(989963.25,1660180.16) 2696.38(2040.36,3421.71) 1,026,155.39(638835.73,1519402.07) 803.11(499.98,1189.15) −1.78(−2.62,−0.93) 1,280,670.28(115716.28,3370347.42) 2639.52(238.50,6946.45) 775,527.37(85798.38,2409225.79) 606.96(67.15,1885.56) −2.45(−3.29,−1.60)
Pertussis Federal Republic of Somalia 168,121.09(126611.49,213243.27) 3552.60(2675.45,4506.09) 201,748.13(128011.14,298129.57) 1578.08(1001.31,2331.98) −0.35(−1.17,0.47) 151,139.68(12178.48,486813.77) 3193.76(257.35,10286.96) 175,643.83(15225.28,506534.12) 1373.89(119.09,3962.13) −0.39(−1.37,0.60)
Pertussis Federated States of Micronesia 560.77(433.30,707.36) 975.30(753.60,1230.23) 15.36(7.45,26.80) 37.06(17.97,64.66) −2.34(−4.31,−0.33) 527.97(47.64,1513.12) 918.24(82.86,2631.62) 187.23(22.12,504.57) 451.76(53.38,1217.48) −1.92(−2.21,−1.63)
Pertussis Federative Republic of Brazil 807,889.06(618050.73,1028264.06) 1202.35(919.82,1530.32) 113,386.65(31790.27,256173.02) 177.40(49.74,400.79) −4.53(−6.80,−2.21) 13,555.08(10777.48,17218.75) 20.17(16.04,25.63) 979.37(238.36,2429.08) 1.53(0.37,3.80) −3.85(−5.27,−2.40)
Pertussis French Republic 69,355.68(53704.08,88570.82) 429.66(332.70,548.70) 2180.55(753.95,4673.90) 13.84(4.79,29.67) −5.03(−6.61,−3.42) 552.20(340.84,846.43) 3.42(2.11,5.24) 24.74(9.68,53.48) 0.16(0.06,0.34) −4.98(−6.49,−3.44)
Pertussis Gabonese Republic 7982.91(6101.07,10144.12) 1570.88(1200.57,1996.16) 6113.46(3132.78,10590.91) 739.19(378.79,1280.57) −1.46(−2.45,−0.47) 7510.26(767.93,24748.33) 1477.87(151.11,4869.98) 3054.00(246.50,9503.23) 369.26(29.80,1149.05) −3.32(−4.39,−2.23)
Pertussis Georgia 23,844.64(18254.20,30326.33) 1327.05(1015.92,1687.78) 75.95(15.83,255.56) 8.17(1.70,27.50) −4.38(−7.16,−1.52) 203.26(129.53,298.75) 11.31(7.21,16.63) 0.70(0.16,1.97) 0.08(0.02,0.21) −4.59(−7.18,−1.92)
Pertussis Grand Duchy of Luxembourg 443.42(342.83,564.73) 502.56(388.56,640.05) 4.51(2.14,7.92) 3.34(1.58,5.87) −8.41(−10.16,−6.62) 3.05(1.79,5.01) 3.46(2.02,5.68) 0.03(0.01,0.06) 0.02(0.01,0.05) −8.42(−10.16,−6.64)
Pertussis Greenland 119.71(92.65,151.95) 669.08(517.83,849.30) 4.13(1.93,7.28) 26.84(12.55,47.38) −3.91(−5.68,−2.12) 63.22(7.23,187.01) 353.36(40.40,1045.20) 0.83(0.12,2.21) 5.43(0.80,14.36) −6.10(−7.94,−4.21)
Pertussis Grenada 490.22(378.91,618.83) 1162.79(898.77,1467.84) 0.70(0.20,3.20) 2.33(0.68,10.63) −6.43(−9.47,−3.29) 3.38(2.01,5.29) 8.01(4.76,12.55) 0.01(0.00,0.02) 0.02(0.01,0.08) −6.29(−9.21,−3.28)
Pertussis Guam 146.50(111.13,190.66) 270.57(205.24,352.14) 2.85(1.37,5.07) 5.87(2.83,10.45) −4.96(−6.86,−3.01) 44.36(5.32,119.19) 81.93(9.83,220.13) 1.84(0.15,5.95) 3.79(0.32,12.28) −4.13(−5.77,−2.46)
Pertussis Hashemite Kingdom of Jordan 9592.41(7436.17,12276.70) 457.51(354.67,585.54) 5938.74(1644.98,13944.00) 120.58(33.40,283.12) −0.53(−2.22,1.19) 4304.37(468.35,11951.52) 205.30(22.34,570.03) 1305.88(134.46,4506.24) 26.51(2.73,91.50) −3.78(−5.43,−2.11)
Pertussis Hellenic Republic 23,148.85(17822.38,29379.75) 823.64(634.12,1045.33) 1.09(0.18,3.43) 0.06(0.01,0.18) −15.86(−19.02,−12.58) 159.16(95.88,252.07) 5.66(3.41,8.97) 0.03(0.00,0.12) 0.00(0.00,0.01) −14.49(−17.17,−11.72)
Pertussis Hungary 3744.34(2808.00,4924.53) 129.02(96.75,169.68) 16.76(5.95,35.98) 0.89(0.32,1.92) −4.69(−7.33,−1.98) 26.44(15.43,43.16) 0.91(0.53,1.49) 0.12(0.04,0.28) 0.01(0.00,0.01) −4.74(−7.36,−2.04)
Pertussis Independent State of Papua New Guinea 47,098.14(35695.40,59884.82) 2212.59(1676.91,2813.29) 4815.57(2308.19,8466.80) 98.30(47.12,172.83) −2.13(−4.07,−0.16) 36,228.21(3712.41,105874.74) 1701.94(174.40,4973.81) 6458.75(266.56,25802.82) 131.84(5.44,526.69) −1.61(−3.28,0.08)
Pertussis Independent State of Samoa 2322.80(1761.35,2954.24) 2535.96(1922.99,3225.35) 71.53(34.44,124.97) 70.86(34.12,123.81) −3.07(−5.48,−0.59) 1064.81(136.04,2682.23) 1162.53(148.52,2928.37) 752.90(101.51,1838.43) 745.88(100.56,1821.27) −1.51(−1.84,−1.17)
Pertussis Ireland 17,580.45(13382.16,22371.94) 1323.02(1007.07,1683.60) 258.59(51.34,787.96) 19.57(3.88,59.62) −6.74(−8.24,−5.21) 121.75(71.69,195.22) 9.16(5.40,14.69) 1.79(0.32,5.91) 0.14(0.02,0.45) −6.76(−8.26,−5.24)
Pertussis Islamic Republic of Afghanistan 196,492.01(147575.33,250319.08) 3525.81(2648.06,4491.67) 62,640.10(28446.76,118169.24) 352.37(160.02,664.74) −3.84(−5.08,−2.59) 225,546.80(24170.00,676155.77) 4047.16(433.70,12132.79) 63,081.93(5957.79,197319.53) 354.86(33.51,1109.99) −4.45(−5.67,−3.22)
Pertussis Islamic Republic of Iran 378,849.59(291890.05,480881.47) 1202.33(926.35,1526.15) 33,060.63(16113.41,62146.50) 127.87(62.32,240.37) −3.04(−5.16,−0.87) 209,882.19(23620.22,585959.51) 666.09(74.96,1859.63) 5888.77(708.59,18452.36) 22.78(2.74,71.37) −6.34(−8.19,−4.46)
Pertussis Islamic Republic of Mauritania 31,852.56(23978.75,40415.46) 2809.06(2114.68,3564.22) 13,720.77(8568.86,20310.98) 588.33(367.42,870.90) −2.31(−3.11,−1.51) 36,061.09(4754.30,100322.00) 3180.21(419.28,8847.35) 10,787.26(1324.54,29080.63) 462.54(56.79,1246.93) −4.38(−5.00,−3.76)
Pertussis Islamic Republic of Pakistan 1,208,840.87(913988.99,1537230.17) 1982.90(1499.24,2521.57) 350,069.19(212123.02,532345.29) 320.51(194.21,487.39) −3.34(−4.13,−2.55) 1,126,429.20(120583.44,3271408.40) 1847.72(197.80,5366.19) 248,105.88(26016.76,802722.39) 227.15(23.82,734.93) −3.31(−4.45,−2.14)
Pertussis Jamaica 8467.16(6550.96,10697.14) 775.02(599.62,979.13) 9.22(2.66,42.02) 1.13(0.33,5.15) −5.54(−8.97,−1.98) 57.94(34.48,91.55) 5.30(3.16,8.38) 0.06(0.02,0.28) 0.01(0.00,0.03) −5.54(−8.97,−1.98)
Pertussis Japan 178,008.43(137584.44,225136.23) 533.54(412.38,674.80) 41.31(1.61,226.93) 0.19(0.01,1.07) −10.70(−14.30,−6.95) 1475.69(982.42,2197.67) 4.42(2.94,6.59) 1.87(0.42,4.33) 0.01(0.00,0.02) −9.66(−12.30,−6.95)
Pertussis Kingdom of Bahrain 1190.56(920.85,1517.16) 594.99(460.20,758.22) 294.17(129.03,561.58) 72.90(31.98,139.17) −2.09(−3.29,−0.87) 504.02(66.41,1503.26) 251.89(33.19,751.27) 50.98(4.42,175.73) 12.63(1.10,43.55) −6.14(−7.00,−5.27)
Pertussis Kingdom of Belgium 10,545.30(8163.28,13465.27) 426.64(330.27,544.77) 321.73(109.39,684.59) 12.65(4.30,26.91) −7.75(−9.31,−6.16) 72.75(42.79,116.58) 2.94(1.73,4.72) 2.32(0.68,5.48) 0.09(0.03,0.22) −7.25(−8.82,−5.64)
Pertussis Kingdom of Bhutan 4473.85(3447.93,5672.45) 1313.47(1012.27,1665.36) 28.04(11.77,52.00) 11.00(4.62,20.39) −13.78(−14.84,−12.70) 3641.68(334.57,12392.57) 1069.15(98.23,3638.30) 9.23(0.38,45.50) 3.62(0.15,17.85) −14.13(−15.58,−12.66)
Pertussis Kingdom of Cambodia 141,122.07(106724.58,179267.37) 2478.69(1874.53,3148.68) 265.80(85.33,572.04) 4.01(1.29,8.63) −8.64(−11.42,−5.78) 129,960.09(11945.18,404866.13) 2282.64(209.81,7111.13) 510.78(7.80,2220.72) 7.70(0.12,33.49) −9.28(−11.37,−7.13)
Pertussis Kingdom of Denmark 5930.35(4583.12,7539.20) 474.32(366.57,603.00) 51.44(8.64,147.68) 3.97(0.67,11.41) −4.85(−7.63,−1.99) 41.34(24.88,65.51) 3.31(1.99,5.24) 0.36(0.05,1.07) 0.03(0.00,0.08) −4.87(−7.62,−2.03)
Pertussis Kingdom of Eswatini 4540.28(3513.65,5735.87) 951.59(736.42,1202.17) 596.16(236.29,1207.90) 111.43(44.17,225.77) −3.02(−4.55,−1.46) 3301.15(361.80,10151.87) 691.88(75.83,2127.71) 856.08(64.62,3158.28) 160.01(12.08,590.33) −1.72(−2.85,−0.59)
Pertussis Kingdom of Lesotho 6905.96(5342.04,8726.32) 824.77(637.99,1042.17) 917.80(364.60,1858.15) 109.41(43.47,221.52) −2.84(−4.58,−1.06) 4968.96(501.54,16177.84) 593.44(59.90,1932.10) 1429.33(116.07,4886.28) 170.40(13.84,582.52) −1.23(−2.40,−0.05)
Pertussis Kingdom of Morocco 128,454.04(99268.20,162141.36) 1029.29(795.43,1299.23) 10,762.56(4720.67,20546.45) 83.33(36.55,159.08) −4.03(−5.31,−2.74) 92,616.13(10123.85,274125.38) 742.13(81.12,2196.55) 4296.70(314.86,14109.90) 33.27(2.44,109.25) −5.72(−6.89,−4.53)
Pertussis Kingdom of Norway 6583.24(5085.88,8338.84) 591.73(457.14,749.53) 77.16(13.31,255.05) 6.22(1.07,20.54) −4.48(−6.86,−2.04) 45.44(27.39,71.56) 4.08(2.46,6.43) 0.57(0.12,1.82) 0.05(0.01,0.15) −4.44(−6.78,−2.04)
Pertussis Kingdom of Saudi Arabia 54,605.05(42257.36,69241.09) 664.99(514.62,843.23) 7731.95(3388.92,14745.30) 76.30(33.44,145.51) −2.83(−3.80,−1.86) 31,529.32(3965.11,92855.66) 383.97(48.29,1130.81) 1522.74(139.93,5385.01) 15.03(1.38,53.14) −7.15(−7.86,−6.43)
Pertussis Kingdom of Spain 51,371.89(39737.97,65007.17) 460.86(356.49,583.18) 1017.96(248.59,2717.19) 11.56(2.82,30.85) −4.89(−6.63,−3.11) 352.82(208.61,557.14) 3.17(1.87,5.00) 12.30(2.66,34.90) 0.14(0.03,0.40) −0.72(−3.22,1.84)
Pertussis Kingdom of Sweden 1581.36(1148.30,2158.87) 75.05(54.50,102.46) 777.41(211.04,1863.76) 32.19(8.74,77.16) 1.62(0.27,2.99) 13.42(8.54,21.36) 0.64(0.41,1.01) 5.68(1.41,14.48) 0.24(0.06,0.60) 0.93(−0.29,2.16)
Pertussis Kingdom of Thailand 162,523.52(125752.32,205303.10) 714.49(552.83,902.56) 616.50(100.07,1738.22) 4.52(0.73,12.74) −3.32(−6.20,−0.37) 66,680.56(7289.70,195479.03) 293.14(32.05,859.37) 357.12(23.47,1240.90) 2.62(0.17,9.09) −5.56(−7.67,−3.39)
Pertussis Kingdom of the Netherlands 6940.41(5238.00,9067.16) 181.07(136.65,236.55) 520.63(76.15,1560.36) 14.11(2.06,42.27) −0.98(−2.79,0.87) 47.90(27.09,77.00) 1.25(0.71,2.01) 4.89(0.89,14.38) 0.13(0.02,0.39) −0.24(−2.03,1.57)
Pertussis Kingdom of Tonga 258.68(199.44,331.27) 484.76(373.74,620.80) 0.69(0.32,1.27) 1.39(0.64,2.56) −9.26(−11.26,−7.22) 102.09(10.58,299.51) 191.32(19.82,561.27) 7.55(0.78,23.41) 15.23(1.56,47.22) −7.06(−7.62,−6.51)
Pertussis Kyrgyz Republic 19,450.41(15044.42,24575.31) 921.21(712.54,1163.94) 3986.84(1160.22,9103.51) 141.24(41.10,322.50) −2.83(−3.82,−1.84) 311.25(189.18,477.65) 14.74(8.96,22.62) 27.53(7.30,68.30) 0.98(0.26,2.42) −4.69(−5.83,−3.54)
Pertussis Lao People’s Democratic Republic 76,720.91(57629.76,97740.02) 3382.04(2540.46,4308.61) 5660.91(2391.55,10988.98) 189.23(79.94,367.34) −4.70(−5.96,−3.43) 70,604.82(6454.45,225545.08) 3112.43(284.53,9942.56) 3495.16(353.14,11261.16) 116.84(11.80,376.44) −5.43(−6.66,−4.18)
Pertussis Lebanese Republic 13,596.10(10470.99,17250.26) 1015.29(781.92,1288.16) 2826.48(1276.39,5333.90) 169.63(76.60,320.12) 0.74(−0.80,2.31) 5306.65(554.70,15035.14) 396.27(41.42,1122.75) 674.52(78.39,2090.32) 40.48(4.70,125.45) −2.34(−3.54,−1.13)
Pertussis Malaysia 107,220.42(82432.54,136288.65) 1285.16(988.05,1633.57) 13,893.08(6246.17,26414.87) 135.47(60.91,257.58) −2.87(−3.78,−1.96) 46,255.62(5516.66,122345.45) 554.43(66.12,1466.45) 3220.76(255.76,11636.85) 31.41(2.49,113.47) −4.75(−5.69,−3.80)
Pertussis Mongolia 14,274.57(11012.81,18079.94) 1257.54(970.19,1592.77) 308.30(19.49,1168.84) 23.49(1.48,89.04) −2.45(−5.00,0.16) 13,460.48(1371.11,44160.68) 1185.82(120.79,3890.39) 586.27(65.30,1615.80) 44.66(4.97,123.09) −4.53(−6.11,−2.93)
Pertussis Montenegro 925.29(716.56,1181.83) 431.33(334.03,550.92) 11.84(4.36,25.24) 7.87(2.90,16.78) −2.00(−4.65,0.72) 266.27(28.06,724.63) 124.13(13.08,337.79) 12.60(1.78,37.57) 8.38(1.19,24.98) −3.57(−4.89,−2.22)
Pertussis New Zealand 10,411.68(8024.96,13267.42) 945.58(728.82,1204.94) 34.11(8.45,78.85) 2.62(0.65,6.05) −7.17(−10.32,−3.91) 71.73(43.25,111.03) 6.51(3.93,10.08) 0.24(0.06,0.57) 0.02(0.00,0.04) −7.18(−10.32,−3.93)
Pertussis North Macedonia 3333.86(2578.54,4255.34) 478.36(369.98,610.58) 30.84(11.37,65.73) 6.91(2.55,14.72) −1.66(−4.48,1.24) 1599.83(205.52,4623.59) 229.55(29.49,663.42) 86.40(7.79,268.23) 19.35(1.74,60.07) −3.58(−4.72,−2.42)
Pertussis Northern Mariana Islands 48.06(36.94,61.57) 296.39(227.82,379.66) 0.80(0.39,1.42) 5.34(2.58,9.50) −4.51(−6.71,−2.25) 13.88(1.70,41.43) 85.61(10.51,255.51) 0.33(0.02,1.24) 2.21(0.15,8.29) −5.33(−7.09,−3.53)
Pertussis Palestine 11,492.93(8895.94,14515.83) 962.90(745.32,1216.16) 615.90(267.37,1188.53) 25.58(11.10,49.36) −8.51(−9.82,−7.17) 5387.91(655.17,14825.05) 451.41(54.89,1242.07) 154.54(15.62,501.80) 6.42(0.65,20.84) −10.06(−11.43,−8.67)
Pertussis People’s Democratic Republic of Algeria 123,001.70(95145.02,155312.84) 910.01(703.91,1149.05) 21,156.08(9397.95,40214.41) 128.62(57.13,244.48) −0.76(−2.51,1.02) 72,939.68(8397.56,224989.18) 539.63(62.13,1664.54) 5862.45(697.62,19420.97) 35.64(4.24,118.07) −3.52(−4.97,−2.04)
Pertussis People’s Republic of Bangladesh 1,622,590.10(1224313.42,2057739.34) 2688.22(2028.38,3409.15) 75,719.64(35866.07,137458.72) 124.15(58.81,225.38) −6.81(−7.68,−5.93) 1,546,845.16(167366.63,4893608.54) 2562.73(277.28,8107.47) 42,926.47(5075.58,126929.38) 70.38(8.32,208.12) −8.78(−9.51,−8.05)
Pertussis People’s Republic of China 3,038,175.30(2351025.67,3855405.97) 682.67(528.27,866.30) 127,448.79(67087.91,219349.98) 38.12(20.07,65.61) −4.95(−6.26,−3.62) 1,947,504.89(177540.86,5834676.36) 437.60(39.89,1311.04) 89,609.37(10053.54,244485.40) 26.80(3.01,73.13) −8.93(−9.69,−8.17)
Pertussis Plurinational State of Bolivia 69,678.91(52851.87,88742.24) 2080.68(1578.21,2649.92) 637.25(138.62,1640.63) 14.02(3.05,36.08) −8.28(−10.26,−6.25) 96,272.78(9447.32,308026.87) 2874.79(282.11,9197.97) 327.53(3.52,1579.96) 7.20(0.08,34.75) −10.31(−12.61,−7.94)
Pertussis Portuguese Republic 16,161.30(12505.66,20431.79) 542.15(419.52,685.41) 92.35(10.67,308.84) 4.82(0.56,16.11) −6.34(−8.28,−4.35) 119.16(71.82,182.99) 4.00(2.41,6.14) 0.92(0.15,2.78) 0.05(0.01,0.15) −5.41(−7.30,−3.49)
Pertussis Principality of Andorra 111.99(85.07,142.79) 832.07(632.06,1060.98) 0.42(0.20,0.74) 2.94(1.39,5.13) −9.53(−11.45,−7.56) 18.82(2.86,54.98) 139.87(21.28,408.48) 0.11(0.01,0.37) 0.77(0.09,2.59) −11.12(−12.32,−9.91)
Pertussis Principality of Monaco 2.95(2.16,3.98) 60.83(44.52,82.12) 0.23(0.11,0.40) 3.35(1.59,5.89) −1.94(−3.82,−0.02) 0.40(0.06,1.16) 8.29(1.15,23.96) 0.04(0.00,0.17) 0.65(0.05,2.49) −3.42(−4.69,−2.13)
Pertussis Puerto Rico 12,959.40(9994.98,16419.40) 972.87(750.33,1232.61) 10.53(3.06,48.08) 1.61(0.47,7.36) −6.90(−10.10,−3.58) 88.91(53.50,139.80) 6.67(4.02,10.50) 0.14(0.03,0.44) 0.02(0.01,0.07) −6.36(−9.21,−3.42)
Pertussis Republic of Albania 5646.73(4371.42,7230.37) 390.53(302.33,500.06) 1.88(0.65,4.10) 0.30(0.11,0.66) −12.27(−14.60,−9.86) 2109.25(247.23,5902.32) 145.88(17.10,408.21) 1.39(0.09,4.73) 0.23(0.01,0.77) −14.16(−15.65,−12.64)
Pertussis Republic of Angola 197,017.94(148134.80,250730.47) 3416.88(2569.10,4348.42) 286,471.78(145037.28,504061.75) 1533.93(776.61,2699.02) −1.37(−1.69,−1.06) 245,732.10(24292.20,739359.90) 4261.73(421.30,12822.71) 228,029.32(23894.74,706447.83) 1220.99(127.95,3782.71) −2.69(−3.13,−2.24)
Pertussis Republic of Armenia 11,022.34(8529.15,13935.00) 830.11(642.34,1049.46) 1680.69(500.69,3713.79) 220.24(65.61,486.66) −1.76(−3.55,0.07) 76.54(46.47,118.84) 5.76(3.50,8.95) 11.58(3.30,26.13) 1.52(0.43,3.42) −1.87(−3.70,−0.01)
Pertussis Republic of Austria 7967.61(6158.51,10166.80) 425.35(328.77,542.75) 393.27(189.46,671.85) 22.41(10.80,38.28) −2.34(−4.39,−0.25) 55.11(31.93,86.77) 2.94(1.70,4.63) 2.78(1.19,5.61) 0.16(0.07,0.32) −2.31(−4.35,−0.24)
Pertussis Republic of Azerbaijan 71,859.42(54166.49,91097.28) 2295.75(1730.50,2910.36) 1250.12(272.97,3054.97) 41.03(8.96,100.27) −5.68(−7.47,−3.86) 35,413.23(3473.50,106323.04) 1131.38(110.97,3396.79) 588.72(59.08,1849.79) 19.32(1.94,60.71) −7.05(−8.56,−5.50)
Pertussis Republic of Belarus 18,642.02(14427.61,23662.83) 594.07(459.77,754.07) 1064.31(253.26,2581.27) 52.55(12.50,127.45) −4.27(−5.93,−2.58) 128.77(75.63,202.09) 4.10(2.41,6.44) 7.47(1.65,17.80) 0.37(0.08,0.88) −4.25(−5.91,−2.57)
Pertussis Republic of Benin 74,222.48(56220.65,94337.37) 2586.42(1959.11,3287.36) 33,295.59(20895.62,49153.09) 442.98(278.00,653.95) −2.74(−3.45,−2.02) 102,049.10(11006.97,309900.90) 3556.09(383.56,10799.07) 31,236.79(2787.27,97713.33) 415.59(37.08,1300.02) −3.62(−4.40,−2.84)
Pertussis Republic of Botswana 4561.97(3525.35,5818.42) 616.09(476.09,785.77) 1324.85(527.34,2683.80) 144.48(57.51,292.67) −0.59(−2.32,1.17) 3023.69(333.88,9819.07) 408.35(45.09,1326.05) 1325.60(135.93,3978.69) 144.56(14.82,433.88) 0.43(−1.08,1.96)
Pertussis Republic of Bulgaria 3766.70(2835.25,4943.83) 159.38(119.97,209.19) 66.26(24.38,140.87) 5.12(1.88,10.88) 0.66(−2.36,3.77) 26.01(13.68,41.94) 1.10(0.58,1.77) 0.48(0.17,1.10) 0.04(0.01,0.08) 0.74(−2.25,3.83)
Pertussis Republic of Burundi 59,692.19(45655.53,75859.49) 1891.91(1447.03,2404.32) 11,667.23(7404.21,16841.97) 160.38(101.78,231.52) −7.94(−8.99,−6.87) 69,400.37(5929.92,239124.44) 2199.61(187.95,7578.91) 9568.64(762.38,32930.79) 131.54(10.48,452.69) −8.30(−9.44,−7.15)
Pertussis Republic of Cabo Verde 2272.01(1755.91,2866.41) 1168.30(902.91,1473.95) 41.21(24.80,64.16) 21.38(12.86,33.29) −8.26(−10.17,−6.31) 1380.70(176.35,3695.83) 709.98(90.68,1900.45) 19.41(1.73,62.22) 10.07(0.90,32.28) −9.05(−10.87,−7.19)
Pertussis Republic of Cameroon 148,781.88(112844.84,189550.05) 2505.98(1900.68,3192.66) 88,430.76(45372.33,145928.71) 523.17(268.43,863.34) −3.16(−3.84,−2.48) 157,325.55(17529.47,455444.70) 2649.89(295.25,7671.21) 80,515.97(6933.35,264654.59) 476.35(41.02,1565.75) −3.61(−4.28,−2.93)
Pertussis Republic of Chad 125,196.64(94157.52,159229.91) 3551.39(2670.92,4516.80) 122,048.38(75606.59,180960.57) 1114.64(690.50,1652.67) −1.79(−2.45,−1.13) 123,897.45(12490.18,400102.14) 3514.54(354.30,11349.50) 138,059.47(11646.27,401350.83) 1260.87(106.36,3665.45) −1.61(−2.23,−0.97)
Pertussis Republic of Chile 21,953.30(17018.43,28128.83) 416.21(322.65,533.29) 471.50(123.58,1089.60) 9.63(2.53,22.27) −5.00(−7.63,−2.29) 303.10(200.58,429.93) 5.75(3.80,8.15) 4.16(1.24,9.36) 0.08(0.03,0.19) −3.18(−7.53,1.37)
Pertussis Republic of Colombia 105,777.27(81846.62,133779.88) 702.71(543.73,888.74) 6507.07(1449.76,16675.77) 44.69(9.96,114.54) −4.19(−5.68,−2.68) 6389.92(4189.08,8921.14) 42.45(27.83,59.27) 189.63(57.32,428.79) 1.30(0.39,2.95) −5.78(−7.13,−4.42)
Pertussis Republic of Costa Rica 9775.16(7564.53,12385.28) 689.29(533.41,873.34) 39.70(12.31,84.34) 2.90(0.90,6.16) −7.14(−10.16,−4.02) 99.47(67.51,145.83) 7.01(4.76,10.28) 0.38(0.14,0.77) 0.03(0.01,0.06) −7.50(−10.60,−4.29)
Pertussis Republic of Croatia 7982.89(6177.61,10094.04) 601.83(465.73,760.99) 33.02(12.13,70.13) 4.10(1.51,8.70) −5.30(−7.83,−2.69) 54.93(32.57,86.89) 4.14(2.46,6.55) 0.23(0.08,0.54) 0.03(0.01,0.07) −5.28(−7.80,−2.69)
Pertussis Republic of Cuba 18,079.53(13972.27,23018.65) 495.06(382.59,630.30) 28.04(8.09,127.74) 1.17(0.34,5.32) −5.47(−8.89,−1.92) 137.04(86.75,208.70) 3.75(2.38,5.71) 0.23(0.06,0.89) 0.01(0.00,0.04) −5.44(−8.75,−2.02)
Pertussis Republic of Cyprus 1461.98(1130.75,1856.90) 564.34(436.48,716.78) 34.97(16.64,60.48) 12.27(5.84,21.21) −3.89(−6.38,−1.34) 346.01(45.36,885.03) 133.56(17.51,341.63) 2.61(0.38,7.79) 0.92(0.13,2.73) −7.92(−10.37,−5.41)
Pertussis Republic of C么te d’Ivoire 173,972.46(131771.29,221095.44) 2514.60(1904.62,3195.71) 41,148.02(23953.52,65424.03) 286.06(166.52,454.82) −2.66(−3.64,−1.67) 176,588.33(16567.43,523283.96) 2552.41(239.47,7563.54) 30,744.88(2206.56,101941.16) 213.73(15.34,708.68) −3.56(−4.60,−2.52)
Pertussis Republic of Djibouti 2588.86(1970.00,3294.77) 1154.33(878.39,1469.09) 4557.54(2911.13,6626.71) 862.56(550.96,1254.18) 0.54(−0.28,1.37) 3898.65(398.05,12314.80) 1738.35(177.48,5490.98) 4554.67(534.03,12133.30) 862.02(101.07,2296.36) −0.49(−1.51,0.55)
Pertussis Republic of Ecuador 59,468.76(45721.43,75589.29) 1199.57(922.26,1524.74) 9400.98(1804.09,25855.48) 142.09(27.27,390.79) −2.60(−3.76,−1.43) 5690.09(3974.42,7611.77) 114.78(80.17,153.54) 143.86(20.72,497.88) 2.17(0.31,7.53) −8.30(−9.49,−7.09)
Pertussis Republic of El Salvador 46,925.82(35775.31,59649.54) 1703.05(1298.37,2164.83) 309.04(63.27,765.49) 12.97(2.66,32.14) −6.97(−9.37,−4.50) 33,212.37(2978.54,100416.17) 1205.36(108.10,3644.35) 264.69(22.76,949.15) 11.11(0.96,39.85) −8.89(−10.80,−6.93)
Pertussis Republic of Equatorial Guinea 7761.55(5830.46,9888.04) 3234.24(2429.56,4120.36) 7935.97(4028.92,13878.89) 1030.47(523.15,1802.15) −2.13(−2.53,−1.72) 9737.38(966.17,30505.20) 4057.57(402.60,12711.55) 3571.21(317.62,11208.04) 463.72(41.24,1455.34) −6.13(−6.43,−5.83)
Pertussis Republic of Estonia 4629.58(3576.39,5841.28) 1007.92(778.62,1271.72) 22.46(5.03,60.76) 8.01(1.79,21.68) −6.29(−8.65,−3.86) 31.80(18.92,49.24) 6.92(4.12,10.72) 0.16(0.03,0.45) 0.06(0.01,0.16) −6.28(−8.65,−3.86)
Pertussis Republic of Fiji 2322.20(1796.46,2938.95) 647.38(500.82,819.32) 28.75(14.01,51.25) 8.20(4.00,14.62) −4.56(−7.43,−1.61) 1342.91(138.72,3870.44) 374.38(38.67,1079.00) 33.86(2.15,131.65) 9.66(0.61,37.55) −4.12(−6.74,−1.41)
Pertussis Republic of Finland 3835.59(2954.54,4914.56) 302.31(232.87,387.35) 224.64(64.87,514.08) 19.56(5.65,44.76) −1.30(−3.39,0.82) 26.80(15.39,43.13) 2.11(1.21,3.40) 1.55(0.34,4.17) 0.13(0.03,0.36) −1.36(−3.43,0.75)
Pertussis Republic of Ghana 181,742.82(137967.92,231631.28) 2200.38(1670.40,2804.39) 32,356.90(20452.95,47501.48) 198.34(125.37,291.17) −4.88(−5.62,−4.14) 152,210.99(16916.75,460210.27) 1842.84(204.81,5571.82) 22,518.41(1658.69,73882.36) 138.03(10.17,452.88) −5.26(−6.02,−4.50)
Pertussis Republic of Guatemala 89,314.35(67981.49,113644.81) 1818.75(1384.34,2314.20) 8427.92(3062.37,18050.82) 127.41(46.29,272.88) −4.26(−5.61,−2.89) 16,955.10(12122.89,22623.49) 345.26(246.86,460.69) 97.66(20.58,378.41) 1.48(0.31,5.72) −10.30(−12.32,−8.22)
Pertussis Republic of Guinea 111,300.47(83712.81,141522.01) 3385.89(2546.64,4305.27) 69,769.70(43348.06,103298.38) 934.69(580.73,1383.87) −1.92(−2.53,−1.31) 163,003.00(14749.04,467496.48) 4958.74(448.68,14221.80) 71,783.65(7539.04,220905.29) 961.67(101.00,2959.43) −2.58(−3.30,−1.87)
Pertussis Republic of Guinea−Bissau 11,686.77(8900.63,14870.47) 1987.22(1513.47,2528.58) 6282.73(3930.48,9283.88) 561.70(351.40,830.01) −2.39(−3.11,−1.67) 17,841.80(1712.53,57291.57) 3033.83(291.20,9741.88) 6478.53(512.67,21578.49) 579.20(45.83,1929.19) −3.44(−4.31,−2.57)
Pertussis Republic of Guyana 5625.40(4340.09,7117.80) 1474.21(1137.38,1865.31) 6.46(1.88,29.47) 2.30(0.67,10.50) −6.66(−9.84,−3.37) 38.78(23.14,60.28) 10.16(6.06,15.80) 0.05(0.01,0.21) 0.02(0.01,0.07) −6.58(−9.70,−3.35)
Pertussis Republic of Haiti 79,427.39(60248.11,101285.61) 2373.50(1800.37,3026.68) 416.08(119.99,1937.32) 7.42(2.14,34.55) −4.78(−7.99,−1.46) 138,753.03(9744.78,418542.95) 4146.31(291.20,12507.17) 4747.07(1.66,17568.54) 84.65(0.03,313.29) −4.32(−6.23,−2.36)
Pertussis Republic of Honduras 23,534.05(18213.24,29733.15) 867.26(671.18,1095.71) 8286.09(2415.77,18852.52) 190.46(55.53,433.34) −1.94(−2.95,−0.91) 20,128.89(2155.22,59114.12) 741.78(79.42,2178.44) 3334.59(317.60,13221.29) 76.65(7.30,303.90) −4.16(−5.16,−3.14)
Pertussis Republic of Iceland 87.53(64.73,116.96) 103.57(76.60,138.39) 297.86(141.32,540.46) 334.29(158.60,606.55) 5.24(4.31,6.17) 0.71(0.42,1.13) 0.83(0.50,1.34) 2.09(0.83,4.31) 2.34(0.93,4.83) 4.73(3.84,5.63)
Pertussis Republic of India 8,324,893.78(6303197.41,10581970.98) 2028.40(1535.81,2578.35) 1,590,226.03(597474.43,3166667.32) 317.68(119.36,632.61) −4.23(−5.14,−3.31) 6,420,361.56(550179.01,21763730.33) 1564.35(134.05,5302.84) 738,460.90(60248.82,2310682.00) 147.52(12.04,461.61) −5.76(−6.69,−4.82)
Pertussis Republic of Indonesia 1,500,916.90(1138721.05,1910577.14) 1716.05(1301.94,2184.43) 30,474.18(11208.89,62840.04) 33.78(12.42,69.65) −3.43(−5.57,−1.23) 989,521.32(110569.78,2724483.56) 1131.36(126.42,3115.00) 24,496.86(2503.96,75337.67) 27.15(2.78,83.51) −4.45(−6.25,−2.62)
Pertussis Republic of Iraq 85,029.17(65788.55,107404.20) 825.64(638.81,1042.91) 42,255.76(19113.30,79335.37) 239.59(108.37,449.83) −0.52(−1.53,0.50) 44,250.76(4736.94,130132.76) 429.68(46.00,1263.60) 6705.64(543.16,24752.60) 38.02(3.08,140.35) −4.11(−5.47,−2.73)
Pertussis Republic of Italy 68,498.13(52938.91,86816.97) 502.93(388.69,637.44) 136.68(64.06,245.88) 1.30(0.61,2.35) −12.71(−14.58,−10.80) 689.15(477.73,966.77) 5.06(3.51,7.10) 1.71(0.85,3.15) 0.02(0.01,0.03) −12.26(−13.89,−10.60)
Pertussis Republic of Kazakhstan 121,231.20(92276.40,154260.33) 1824.92(1389.05,2322.11) 3588.28(1387.71,7073.73) 53.36(20.64,105.20) −5.92(−7.99,−3.79) 832.85(494.36,1282.20) 12.54(7.44,19.30) 25.01(8.56,52.34) 0.37(0.13,0.78) −6.10(−8.12,−4.04)
Pertussis Republic of Kenya 152,363.23(117943.66,193327.19) 1104.74(855.17,1401.75) 77,556.79(50366.15,111954.42) 315.27(204.74,455.09) −2.66(−3.46,−1.86) 96,427.29(8889.99,278984.22) 699.16(64.46,2022.82) 52,283.16(3948.38,137536.54) 212.53(16.05,559.08) −2.13(−2.86,−1.40)
Pertussis Republic of Kiribati 803.30(609.70,1023.77) 2191.64(1663.43,2793.14) 37.63(18.12,65.74) 70.41(33.90,123.01) −2.60(−4.60,−0.56) 900.48(84.20,2739.33) 2456.76(229.71,7473.67) 801.41(86.14,2112.38) 1499.50(161.17,3952.43) −1.01(−1.45,−0.57)
Pertussis Republic of Korea 121,567.31(93791.79,153905.48) 763.27(588.88,966.31) 3.43(2.58,4.48) 0.04(0.03,0.05) −10.21(−15.03,−5.12) 37,268.65(5046.29,108874.51) 234.00(31.68,683.58) 17.06(0.03,102.78) 0.20(0.00,1.23) −11.86(−14.21,−9.44)
Pertussis Republic of Latvia 4347.44(3359.45,5534.70) 577.80(446.49,735.59) 0.56(0.02,3.17) 0.14(0.01,0.82) −14.57(−17.50,−11.53) 29.90(17.33,47.38) 3.97(2.30,6.30) 0.04(0.01,0.14) 0.01(0.00,0.04) −12.91(−14.69,−11.09)
Pertussis Republic of Liberia 71,006.69(53407.72,90232.02) 5197.52(3909.32,6604.76) 7708.43(4865.41,11343.83) 276.28(174.39,406.58) −4.43(−5.74,−3.11) 70,198.59(6967.92,207840.88) 5138.37(510.04,15213.45) 5701.90(421.66,19449.26) 204.37(15.11,697.10) −6.61(−7.63,−5.57)
Pertussis Republic of Lithuania 9675.39(7479.27,12214.09) 873.52(675.25,1102.72) 965.35(419.85,1853.27) 180.17(78.36,345.89) −2.89(−4.10,−1.66) 66.20(39.50,103.60) 5.98(3.57,9.35) 6.63(2.58,13.40) 1.24(0.48,2.50) −2.88(−4.09,−1.66)
Pertussis Republic of Madagascar 135,192.61(102831.83,172180.94) 2010.00(1528.87,2559.94) 80,047.98(29651.32,156239.26) 535.66(198.42,1045.51) −2.41(−3.28,−1.53) 152,297.74(14366.10,525521.87) 2264.32(213.59,7813.31) 57,568.38(3784.19,214058.38) 385.23(25.32,1432.43) −3.48(−4.39,−2.56)
Pertussis Republic of Malawi 92,706.09(71358.20,117685.67) 1663.40(1280.36,2111.60) 20,751.89(13166.61,30007.49) 195.94(124.32,283.33) −4.55(−5.51,−3.57) 117,473.40(11345.81,399121.00) 2107.79(203.57,7161.32) 19,350.54(1850.78,62437.70) 182.71(17.48,589.54) −5.19(−6.24,−4.13)
Pertussis Republic of Maldives 2053.62(1573.97,2615.95) 1600.09(1226.37,2038.24) 33.15(16.25,58.19) 25.44(12.47,44.66) −4.55(−6.86,−2.19) 1129.39(113.68,3711.29) 879.98(88.58,2891.68) 9.17(0.73,37.09) 7.04(0.56,28.47) −7.21(−9.42,−4.94)
Pertussis Republic of Mali 175,894.54(132298.63,223517.15) 3556.40(2674.93,4519.27) 87,384.22(54649.80,129154.50) 613.95(383.96,907.42) −3.19(−3.90,−2.48) 206,804.75(20743.09,635559.79) 4181.37(419.40,12850.33) 66,926.63(5697.43,220555.16) 470.22(40.03,1549.60) −4.20(−4.95,−3.43)
Pertussis Republic of Malta 1287.08(987.27,1639.33) 1116.77(856.63,1422.41) 7.97(3.80,13.87) 9.49(4.52,16.52) −6.46(−8.80,−4.07) 8.85(5.37,13.98) 7.68(4.66,12.13) 0.06(0.02,0.11) 0.07(0.03,0.13) −6.46(−8.79,−4.07)
Pertussis Republic of Mauritius 2622.11(2028.88,3316.23) 608.64(470.94,769.76) 30.57(14.93,53.99) 10.30(5.03,18.18) −6.95(−8.69,−5.18) 17.96(10.85,28.36) 4.17(2.52,6.58) 0.21(0.08,0.43) 0.07(0.03,0.15) −6.96(−8.69,−5.19)
Pertussis Republic of Moldova 14,502.00(11220.44,18313.36) 917.11(709.58,1158.14) 280.32(92.14,588.40) 40.26(13.23,84.51) −2.60(−4.69,−0.45) 115.33(71.82,170.70) 7.29(4.54,10.80) 1.95(0.56,4.70) 0.28(0.08,0.68) −3.03(−5.06,−0.96)
Pertussis Republic of Mozambique 206,926.00(156423.87,262784.97) 2733.25(2066.17,3471.08) 29,085.18(18465.99,41954.72) 163.82(104.01,236.31) −6.66(−7.86,−5.44) 314,095.02(32467.38,944748.18) 4148.82(428.86,12479.00) 38,887.17(3558.52,130562.64) 219.03(20.04,735.39) −6.59(−7.80,−5.37)
Pertussis Republic of Namibia 19,744.24(14857.23,25059.67) 2592.20(1950.59,3290.05) 953.41(375.42,1923.75) 88.99(35.04,179.56) −5.82(−7.57,−4.03) 11,788.10(1309.59,33728.82) 1547.65(171.93,4428.22) 868.82(63.62,2977.37) 81.09(5.94,277.90) −4.93(−6.39,−3.45)
Pertussis Republic of Nauru 60.95(47.04,77.06) 1169.83(902.82,1478.89) 0.21(0.10,0.38) 4.10(1.95,7.40) −9.89(−12.68,−7.01) 56.53(6.43,162.25) 1084.95(123.49,3113.98) 3.80(0.38,14.13) 74.04(7.38,275.53) −8.39(−10.09,−6.65)
Pertussis Republic of Nicaragua 33,611.74(25741.22,42766.34) 1493.68(1143.92,1900.50) 61.84(19.59,132.14) 2.38(0.75,5.08) −17.02(−19.14,−14.83) 21,886.90(2245.93,64599.94) 972.64(99.81,2870.77) 23.19(1.98,88.99) 0.89(0.08,3.42) −18.41(−20.36,−16.42)
Pertussis Republic of Niue 2.29(1.74,2.97) 223.63(169.89,290.55) 0.03(0.01,0.05) 5.70(2.77,10.18) −2.10(−4.49,0.34) 1.69(0.13,5.24) 165.04(12.57,512.67) 0.38(0.04,1.17) 71.95(7.34,220.64) −1.12(−1.92,−0.30)
Pertussis Republic of Palau 30.25(23.40,38.27) 490.69(379.51,620.79) 0.56(0.28,0.99) 12.76(6.22,22.38) −2.61(−5.33,0.19) 18.31(1.99,55.65) 296.94(32.29,902.64) 5.18(0.48,16.06) 116.98(10.90,362.71) −1.72(−2.89,−0.55)
Pertussis Republic of Panama 8803.92(6814.21,11119.34) 809.90(626.86,1022.91) 3692.89(794.57,9006.93) 245.01(52.72,597.58) −0.32(−1.78,1.18) 747.49(423.98,1114.57) 68.76(39.00,102.53) 29.04(7.27,71.63) 1.93(0.48,4.75) −7.81(−9.40,−6.19)
Pertussis Republic of Paraguay 30,630.32(23472.32,39011.09) 1480.37(1134.42,1885.41) 1360.16(361.74,3066.67) 50.93(13.54,114.83) −6.20(−7.94,−4.43) 14,764.05(1634.71,39749.93) 713.55(79.01,1921.12) 445.91(27.59,1927.20) 16.70(1.03,72.16) −7.43(−9.08,−5.75)
Pertussis Republic of Peru 122,955.32(94800.89,155829.22) 1154.54(890.17,1463.22) 74,675.90(19854.71,174121.91) 596.91(158.70,1391.80) −2.31(−3.58,−1.02) 86,809.10(9414.20,255502.48) 815.13(88.40,2399.15) 16,862.64(836.14,68016.93) 134.79(6.68,543.68) −5.78(−7.19,−4.34)
Pertussis Republic of Poland 38,444.96(29664.04,49240.90) 308.81(238.27,395.53) 330.85(34.15,1214.57) 4.30(0.44,15.78) −4.71(−6.98,−2.39) 318.07(206.13,479.11) 2.55(1.66,3.85) 2.32(0.22,8.62) 0.03(0.00,0.11) −5.04(−7.27,−2.75)
Pertussis Republic of Rwanda 45,186.40(34963.12,57074.45) 1091.81(844.79,1379.05) 8496.20(5387.55,12249.83) 131.97(83.68,190.27) −7.32(−8.29,−6.34) 68,573.01(7634.76,226834.78) 1656.88(184.47,5480.85) 7935.07(828.66,25386.51) 123.25(12.87,394.32) −8.66(−9.72,−7.59)
Pertussis Republic of San Marino 7.03(5.29,9.21) 117.48(88.43,153.90) 1.21(0.59,2.07) 19.42(9.38,33.16) 2.59(0.23,5.00) 1.26(0.18,3.69) 21.09(3.05,61.75) 0.23(0.02,1.00) 3.61(0.27,16.03) 0.51(−1.18,2.24)
Pertussis Republic of Senegal 97,755.33(74356.96,124499.23) 2198.26(1672.09,2799.66) 19,650.26(10213.37,33688.97) 242.14(125.85,415.13) −5.66(−6.46,−4.86) 123,456.30(12883.29,390129.74) 2776.21(289.71,8772.99) 17,731.89(2028.50,58714.72) 218.50(25.00,723.51) −5.86(−6.67,−5.04)
Pertussis Republic of Serbia 16,172.94(12515.77,20505.35) 557.48(431.41,706.81) 121.60(44.76,259.45) 6.49(2.39,13.85) −2.68(−5.52,0.24) 6701.01(719.17,18658.29) 230.98(24.79,643.15) 166.10(11.34,507.51) 8.86(0.60,27.08) −5.38(−6.67,−4.06)
Pertussis Republic of Seychelles 121.29(94.04,155.32) 388.25(301.01,497.15) 2.73(1.33,4.87) 8.95(4.37,15.96) −2.72(−4.84,−0.57) 45.43(5.16,128.63) 145.43(16.52,411.72) 1.73(0.15,5.55) 5.68(0.50,18.18) −3.28(−4.83,−1.70)
Pertussis Republic of Sierra Leone 68,395.21(51916.22,87160.54) 3100.83(2353.72,3951.60) 15,234.04(9596.71,22416.99) 334.77(210.89,492.61) −5.09(−5.93,−4.25) 75,071.53(5922.05,234056.93) 3403.52(268.49,10611.43) 14,901.77(1250.39,52163.62) 327.46(27.48,1146.29) −5.50(−6.35,−4.64)
Pertussis Republic of Singapore 5520.96(4272.43,6981.16) 599.47(463.91,758.02) 22.79(2.37,79.93) 2.18(0.23,7.66) −4.50(−7.72,−1.17) 38.31(22.43,62.06) 4.16(2.44,6.74) 0.16(0.02,0.58) 0.02(0.00,0.06) −4.50(−7.71,−1.18)
Pertussis Republic of Slovenia 979.24(740.12,1279.57) 175.88(132.93,229.82) 16.12(3.43,49.64) 3.98(0.85,12.26) −0.17(−3.16,2.91) 6.79(3.85,10.88) 1.22(0.69,1.95) 0.11(0.02,0.35) 0.03(0.01,0.09) −0.17(−3.16,2.90)
Pertussis Republic of South Africa 200,904.76(155158.30,255076.89) 1140.10(880.50,1447.52) 43,986.30(17556.08,88712.92) 220.84(88.14,445.39) −0.89(−2.64,0.89) 124,319.06(15128.83,375578.41) 705.49(85.85,2131.34) 14,841.99(1595.39,41794.33) 74.52(8.01,209.83) −2.19(−4.20,−0.15)
Pertussis Republic of South Sudan 93,512.48(70385.45,118637.84) 2845.73(2141.94,3610.33) 50,319.02(32146.47,73203.61) 917.00(585.83,1334.04) −2.07(−2.99,−1.14) 98,907.72(9185.90,317095.15) 3009.91(279.54,9649.68) 39,458.96(3417.39,137986.77) 719.09(62.28,2514.64) −2.62(−3.60,−1.63)
Pertussis Republic of Sudan 299,755.86(225523.13,380554.57) 2713.67(2041.65,3445.14) 53,412.37(24180.48,100129.95) 249.88(113.12,468.44) −3.91(−4.94,−2.86) 279,193.13(30209.21,886029.77) 2527.52(273.48,8021.18) 29,011.53(2142.75,90766.39) 135.73(10.02,424.64) −5.77(−6.80,−4.72)
Pertussis Republic of Suriname 1579.82(1221.45,1994.47) 923.92(714.33,1166.42) 8.17(2.37,37.59) 4.30(1.25,19.80) −2.44(−5.85,1.10) 1063.04(102.52,3064.21) 621.69(59.96,1792.03) 27.31(2.48,93.71) 14.38(1.31,49.36) −2.45(−4.70,−0.15)
Pertussis Republic of Tajikistan 37,898.05(29270.37,47847.28) 1318.43(1018.28,1664.55) 2688.94(1243.06,4832.62) 60.36(27.90,108.47) −4.39(−5.92,−2.83) 23,432.42(1844.86,73719.32) 815.19(64.18,2564.61) 1575.68(82.99,6307.00) 35.37(1.86,141.57) −4.65(−6.11,−3.16)
Pertussis Republic of the Congo 15,809.74(12184.28,20045.47) 1191.67(918.40,1510.94) 22,977.75(11729.42,39894.93) 923.97(471.66,1604.24) −0.20(−1.18,0.79) 19,663.08(1703.05,62185.59) 1482.12(128.37,4687.29) 14,089.83(1543.19,48698.82) 566.58(62.05,1958.26) −2.45(−3.45,−1.44)
Pertussis Republic of the Gambia 5567.41(4307.72,7033.63) 991.01(766.78,1252.00) 2951.05(1866.54,4337.16) 232.99(147.36,342.42) −3.06(−3.90,−2.21) 4882.91(370.90,14855.93) 869.17(66.02,2644.38) 2336.67(159.83,7533.28) 184.48(12.62,594.76) −3.59(−4.49,−2.67)
Pertussis Republic of the Marshall Islands 340.93(261.69,434.00) 1273.00(977.12,1620.50) 7.87(3.83,13.72) 34.09(16.58,59.45) −3.65(−5.78,−1.47) 243.00(27.91,664.03) 907.33(104.22,2479.40) 136.74(15.99,372.66) 592.67(69.31,1615.21) −1.42(−2.32,−0.51)
Pertussis Republic of the Niger 167,272.09(125817.89,212445.19) 3447.78(2593.33,4378.87) 124,456.29(77657.25,184684.15) 798.47(498.23,1184.88) −3.62(−4.23,−3.00) 219,712.85(17519.70,693403.99) 4528.67(361.11,14292.29) 113,804.04(9946.67,400499.44) 730.13(63.81,2569.48) −4.86(−5.50,−4.22)
Pertussis Republic of the Philippines 457,298.22(350610.20,582268.86) 1426.71(1093.86,1816.60) 52,575.23(22424.61,98900.41) 117.41(50.08,220.87) −2.60(−3.99,−1.19) 248,174.33(27385.74,724343.93) 774.27(85.44,2259.86) 22,494.82(2347.71,97694.77) 50.24(5.24,218.18) −3.15(−4.63,−1.64)
Pertussis Republic of the Union of Myanmar 324,404.14(246159.69,413508.15) 1697.45(1288.04,2163.69) 9353.62(4535.53,16367.86) 45.04(21.84,78.81) −2.40(−4.51,−0.25) 363,240.90(35717.78,1154151.59) 1900.67(186.89,6039.12) 8580.60(472.39,33055.07) 41.32(2.27,159.16) −4.37(−6.20,−2.50)
Pertussis Republic of Trinidad and Tobago 7029.22(5386.56,8952.48) 1353.14(1036.93,1723.38) 14.42(4.18,66.34) 3.96(1.15,18.23) −3.38(−6.86,0.24) 48.13(28.68,74.34) 9.27(5.52,14.31) 0.10(0.02,0.45) 0.03(0.01,0.12) −3.37(−6.86,0.24)
Pertussis Republic of Tunisia 31,209.73(24150.59,39426.84) 782.19(605.27,988.13) 2256.19(992.41,4309.88) 62.92(27.68,120.20) −3.50(−5.04,−1.93) 16,355.98(1528.66,49549.16) 409.92(38.31,1241.82) 321.59(40.69,1117.40) 8.97(1.13,31.16) −7.08(−8.53,−5.61)
Pertussis Republic of Turkey 227,418.12(175811.12,287097.07) 852.34(658.92,1076.01) 18,532.31(8115.35,35313.78) 74.99(32.84,142.90) −5.28(−6.80,−3.73) 147,650.87(21149.08,446557.88) 553.38(79.26,1673.65) 3469.24(414.75,10490.24) 14.04(1.68,42.45) −10.14(−11.60,−8.66)
Pertussis Republic of Uganda 248,650.30(188903.03,317020.55) 2414.60(1834.40,3078.53) 143,047.35(53018.74,299232.91) 573.48(212.56,1199.64) −3.49(−4.19,−2.79) 190,992.95(21913.72,577708.74) 1854.70(212.80,5610.03) 126,087.06(12156.82,462853.37) 505.49(48.74,1855.60) −3.08(−3.79,−2.37)
Pertussis Republic of Uzbekistan 16,201.31(12030.30,21550.29) 151.76(112.69,201.86) 5795.37(2677.37,10441.24) 45.96(21.23,82.80) 0.27(−1.68,2.25) 474.27(241.69,737.35) 4.44(2.26,6.91) 40.53(16.10,78.93) 0.32(0.13,0.63) −2.54(−4.21,−0.85)
Pertussis Republic of Vanuatu 2039.11(1546.64,2597.27) 2443.56(1853.42,3112.43) 42.73(20.95,75.02) 28.98(14.21,50.88) −4.53(−7.02,−1.98) 1118.20(138.50,3197.69) 1339.99(165.97,3831.95) 88.12(7.73,260.91) 59.77(5.24,176.96) −3.23(−4.98,−1.45)
Pertussis Republic of Yemen 233,216.74(175637.94,295791.84) 2773.72(2088.92,3517.94) 54,201.39(24611.49,102236.08) 310.22(140.86,585.14) −2.62(−3.75,−1.49) 151,805.40(15063.97,471471.36) 1805.47(179.16,5607.35) 34,631.76(3618.94,107480.51) 198.21(20.71,615.15) −3.58(−4.50,−2.66)
Pertussis Republic of Zambia 65,216.93(50331.35,82447.53) 1387.45(1070.77,1754.02) 39,610.36(22321.68,63482.64) 378.89(213.52,607.24) −3.06(−3.69,−2.43) 89,859.44(8484.01,276163.77) 1911.70(180.49,5875.21) 28,351.42(1486.50,104186.19) 271.20(14.22,996.59) −4.50(−5.44,−3.56)
Pertussis Republic of Zimbabwe 40,901.60(31623.43,51955.18) 679.16(525.10,862.70) 7407.48(2913.47,14955.54) 92.78(36.49,187.31) −2.16(−4.68,0.43) 23,046.43(2684.69,70181.50) 382.68(44.58,1165.35) 5977.42(202.64,25681.38) 74.87(2.54,321.65) 0.21(−2.37,2.85)
Pertussis Romania 26,741.02(20728.82,34238.96) 356.41(276.28,456.35) 171.20(23.04,587.28) 4.24(0.57,14.53) 0.11(−3.17,3.49) 425.91(287.05,616.67) 5.68(3.83,8.22) 1.29(0.23,4.39) 0.03(0.01,0.11) −1.11(−4.48,2.39)
Pertussis Russian Federation 668,080.75(509830.16,851634.59) 1478.54(1128.32,1884.77) 7997.01(2008.47,17744.68) 23.67(5.94,52.52) −6.84(−8.46,−5.19) 5605.06(3750.54,8172.73) 12.40(8.30,18.09) 92.66(30.29,183.57) 0.27(0.09,0.54) −6.75(−8.16,−5.32)
Pertussis Saint Kitts and Nevis 40.15(30.37,52.44) 218.56(165.32,285.47) 0.14(0.04,0.63) 0.98(0.28,4.45) −2.48(−5.80,0.95) 0.29(0.17,0.45) 1.56(0.92,2.45) 0.00(0.00,0.00) 0.01(0.00,0.03) −3.67(−6.89,−0.34)
Pertussis Saint Lucia 439.25(339.75,555.55) 657.79(508.79,831.95) 0.88(0.26,4.01) 2.09(0.61,9.55) −5.22(−8.31,−2.04) 3.12(1.90,4.79) 4.67(2.85,7.18) 0.01(0.00,0.03) 0.01(0.00,0.07) −5.44(−8.48,−2.30)
Pertussis Saint Vincent and the Grenadines 121.61(92.54,157.77) 226.24(172.16,293.51) 0.26(0.07,1.17) 0.77(0.22,3.49) −2.74(−6.24,0.88) 0.88(0.52,1.41) 1.64(0.96,2.62) 0.00(0.00,0.01) 0.01(0.00,0.02) −2.76(−6.18,0.79)
Pertussis Slovak Republic 2658.27(1997.67,3487.44) 151.45(113.81,198.69) 54.93(16.05,127.68) 4.90(1.43,11.39) −1.15(−3.52,1.29) 699.86(102.80,1885.80) 39.87(5.86,107.44) 60.71(6.73,173.33) 5.42(0.60,15.46) −2.28(−3.57,−0.97)
Pertussis Socialist Republic of Viet Nam 448,886.35(345031.73,570732.28) 1333.32(1024.84,1695.23) 11,104.70(3089.59,25658.29) 35.12(9.77,81.15) −2.60(−4.73,−0.42) 213,884.74(29320.29,622492.81) 635.30(87.09,1848.98) 3927.92(337.58,13402.45) 12.42(1.07,42.39) −4.59(−6.44,−2.69)
Pertussis Solomon Islands 3125.08(2389.06,3971.03) 1605.76(1227.57,2040.43) 91.17(44.70,160.01) 27.57(13.51,48.38) −4.63(−6.71,−2.50) 2456.88(266.63,7601.14) 1262.42(137.00,3905.69) 1618.76(154.48,4772.30) 489.43(46.71,1442.90) −2.54(−2.89,−2.19)
Pertussis State of Eritrea 71,167.27(53525.29,90602.10) 3618.45(2721.46,4606.60) 8337.13(5316.98,12030.51) 259.19(165.30,374.01) −7.82(−9.56,−6.05) 72,161.17(7380.23,229091.26) 3668.98(375.24,11647.98) 11,853.13(1034.70,39153.25) 368.49(32.17,1217.21) −6.97(−8.39,−5.53)
Pertussis State of Israel 8451.70(6551.61,10815.90) 421.26(326.55,539.09) 321.49(152.92,560.92) 9.53(4.53,16.63) −2.83(−5.05,−0.56) 58.73(35.04,93.83) 2.93(1.75,4.68) 2.36(0.93,4.86) 0.07(0.03,0.14) −2.39(−4.71,−0.01)
Pertussis State of Kuwait 3148.82(2430.39,4031.54) 459.04(354.31,587.73) 767.58(336.87,1466.54) 70.07(30.75,133.87) −4.38(−5.89,−2.86) 21.79(12.51,34.85) 3.18(1.82,5.08) 5.28(1.99,11.00) 0.48(0.18,1.00) −4.39(−5.90,−2.87)
Pertussis State of Libya 17,736.58(13724.82,22415.15) 768.39(594.59,971.07) 2912.41(1316.50,5475.72) 139.51(63.07,262.31) −0.88(−2.09,0.34) 7430.22(1015.60,20536.59) 321.89(44.00,889.69) 780.51(79.42,2587.19) 37.39(3.80,123.94) −2.57(−3.62,−1.51)
Pertussis State of Qatar 2000.92(1545.64,2525.43) 1307.11(1009.70,1649.76) 60.02(20.11,127.06) 10.05(3.37,21.28) −6.56(−8.66,−4.41) 616.43(82.84,1677.54) 402.68(54.11,1095.86) 30.59(3.46,96.35) 5.12(0.58,16.14) −8.79(−10.01,−7.55)
Pertussis Sultanate of Oman 7564.26(5849.21,9608.22) 754.69(583.58,958.62) 383.30(135.17,777.96) 25.69(9.06,52.15) −5.19(−6.74,−3.61) 2970.46(385.24,9382.42) 296.37(38.44,936.09) 62.29(6.68,211.89) 4.18(0.45,14.20) −7.74(−9.38,−6.08)
Pertussis Swiss Confederation 7235.59(5591.37,9228.14) 458.77(354.52,585.11) 185.14(88.29,320.98) 10.50(5.01,18.21) −5.19(−7.02,−3.33) 50.11(29.21,79.80) 3.18(1.85,5.06) 1.35(0.58,2.69) 0.08(0.03,0.15) −5.13(−6.93,−3.29)
Pertussis Syrian Arab Republic 68,651.85(53026.85,86636.51) 933.79(721.26,1178.42) 11,141.59(5057.42,21007.79) 204.80(92.97,386.17) 0.94(−0.59,2.50) 38,996.08(5288.75,115930.78) 530.42(71.94,1576.88) 3103.89(345.07,7732.78) 57.06(6.34,142.14) −2.27(−3.56,−0.97)
Pertussis Taiwan (Province of China) 35,297.85(27296.00,44835.42) 482.94(373.46,613.43) 1091.34(570.67,1869.58) 26.98(14.11,46.21) −5.68(−6.66,−4.69) 243.37(146.17,388.93) 3.33(2.00,5.32) 7.56(3.36,14.74) 0.19(0.08,0.36) −5.59(−6.58,−4.58)
Pertussis Togolese Republic 36,439.81(27877.88,46318.57) 1692.73(1295.01,2151.63) 27,194.07(14462.02,44220.41) 651.29(346.36,1059.07) −1.95(−2.74,−1.15) 33,433.48(3695.43,106965.83) 1553.08(171.66,4968.86) 19,020.37(1803.06,58231.54) 455.53(43.18,1394.63) −2.91(−3.72,−2.09)
Pertussis Tokelau 4.96(3.83,6.25) 653.48(504.70,824.30) 0.04(0.02,0.07) 7.92(3.86,14.02) −6.66(−8.35,−4.93) 4.73(0.52,15.02) 623.44(69.10,1980.29) 0.44(0.04,1.36) 86.18(7.59,266.33) −6.31(−6.81,−5.80)
Pertussis Turkmenistan 23,369.29(18029.81,29564.50) 1239.60(956.37,1568.21) 100.18(44.05,184.78) 5.11(2.25,9.43) −11.10(−12.82,−9.35) 168.38(105.77,261.43) 8.93(5.61,13.87) 1.43(0.53,3.14) 0.07(0.03,0.16) −10.29(−11.64,−8.92)
Pertussis Tuvalu 86.55(66.77,109.61) 2025.37(1562.63,2565.14) 0.95(0.46,1.66) 19.29(9.44,33.73) −6.82(−8.69,−4.91) 71.65(6.77,222.47) 1676.81(158.42,5206.35) 12.56(1.55,35.79) 255.57(31.62,728.41) −5.95(−6.76,−5.14)
Pertussis Ukraine 158,756.61(122507.72,201197.54) 1054.74(813.91,1336.71) 2887.73(1477.11,4800.31) 34.19(17.49,56.84) 4.02(0.12,8.08) 1411.94(923.02,2061.85) 9.38(6.13,13.70) 20.95(9.04,40.97) 0.25(0.11,0.49) 1.96(−1.52,5.56)
Pertussis Union of the Comoros 4595.89(3519.47,5846.78) 1738.78(1331.53,2212.03) 1195.92(770.20,1717.96) 380.93(245.33,547.21) −3.01(−3.91,−2.11) 5729.12(549.37,16600.62) 2167.51(207.84,6280.56) 1356.33(149.51,4057.72) 432.03(47.62,1292.48) −3.63(−4.48,−2.77)
Pertussis United Arab Emirates 5203.77(4027.35,6605.28) 736.02(569.62,934.24) 1264.86(554.79,2414.67) 74.62(32.73,142.45) −3.12(−4.22,−2.00) 2525.01(297.68,7653.02) 357.13(42.10,1082.43) 368.61(46.11,1109.63) 21.75(2.72,65.46) −5.34(−6.31,−4.36)
Pertussis United Kingdom of Great Britain and Northern Ireland 137,688.93(106382.03,174403.37) 928.20(717.15,1175.70) 2208.05(1054.46,3770.45) 14.10(6.74,24.09) −4.36(−6.29,−2.39) 1015.72(640.01,1541.78) 6.85(4.31,10.39) 22.14(12.85,37.84) 0.14(0.08,0.24) −3.76(−5.83,−1.65)
Pertussis United Mexican States 747,028.43(569403.71,949430.02) 1722.57(1312.98,2189.28) 44,732.94(20955.96,83601.28) 103.67(48.56,193.74) −2.15(−3.79,−0.47) 30,454.12(22500.80,37654.70) 70.22(51.88,86.83) 1037.20(533.45,1763.22) 2.40(1.24,4.09) −2.89(−4.92,−0.82)
Pertussis United Republic of Tanzania 209,550.94(161616.50,265499.08) 1404.19(1082.99,1779.10) 103,767.44(62910.37,156319.38) 336.27(203.87,506.57) −3.73(−4.24,−3.21) 250,089.88(24408.89,744989.25) 1675.84(163.56,4992.15) 102,774.74(10388.82,318416.81) 333.05(33.67,1031.87) −3.36(−4.08,−2.64)
Pertussis United States of America 96,904.73(72274.86,128064.48) 130.87(97.61,172.95) 39,393.62(17137.92,74879.65) 48.45(21.08,92.09) −0.70(−2.13,0.75) 1149.91(832.60,1587.20) 1.55(1.12,2.14) 350.09(142.41,722.00) 0.43(0.18,0.89) −0.54(−2.04,0.98)
Pertussis United States Virgin Islands 586.77(449.47,746.96) 1406.62(1077.48,1790.64) 0.92(0.27,4.28) 5.07(1.47,23.49) −4.10(−7.34,−0.75) 235.60(35.76,544.96) 564.79(85.72,1306.40) 5.27(0.19,15.75) 28.94(1.02,86.45) −3.28(−4.74,−1.79)
Typhoid fever American Samoa 65.61(43.22,92.69) 274.20(180.63,387.39) 12.92(8.88,18.62) 67.53(46.41,97.34) −4.45(−4.50,−4.39) 46.77(20.76,89.60) 195.47(86.77,374.50) 11.78(5.28,23.34) 61.59(27.61,122.00) −3.42(−3.60,−3.23)
Typhoid fever Antigua and Barbuda 0.41(0.24,0.68) 1.71(0.99,2.84) 0.16(0.08,0.27) 0.68(0.36,1.15) −2.55(−2.78,−2.32) 0.01(0.00,0.01) 0.02(0.01,0.04) 0.00(0.00,0.00) 0.01(0.00,0.01) −3.26(−3.78,−2.74)
Typhoid fever Arab Republic of Egypt 39,996.45(28504.04,52328.44) 143.24(102.08,187.40) 13,137.18(9107.01,17413.37) 28.22(19.56,37.41) −5.08(−5.20,−4.96) 39,277.31(18261.62,71663.73) 140.66(65.40,256.65) 14,343.21(6617.27,26820.87) 30.81(14.22,57.62) −4.41(−4.67,−4.15)
Typhoid fever Argentine Republic 162.99(92.38,264.94) 1.25(0.71,2.03) 55.57(32.06,88.76) 0.41(0.23,0.65) −3.23(−3.80,−2.65) 85.73(65.44,108.94) 0.66(0.50,0.84) 3.18(2.30,4.54) 0.02(0.02,0.03) −6.08(−8.99,−3.08)
Typhoid fever Australia 0.64(0.25,1.18) 0.01(0.00,0.02) 1.38(0.64,2.48) 0.02(0.01,0.04) 0.94(0.51,1.38) 0.03(0.02,0.04) 0.00(0.00,0.00) 0.03(0.02,0.04) 0.00(0.00,0.00) 0.91(−0.72,2.57)
Typhoid fever Barbados 5.07(3.06,7.78) 5.97(3.60,9.16) 2.41(1.39,3.79) 3.63(2.10,5.71) −1.69(−1.81,−1.56) 0.05(0.03,0.09) 0.06(0.03,0.11) 0.02(0.01,0.04) 0.04(0.02,0.06) −1.59(−1.68,−1.50)
Typhoid fever Belize 2.32(1.43,3.58) 2.26(1.39,3.49) 2.28(1.44,3.41) 1.35(0.85,2.01) −1.21(−1.39,−1.04) 0.19(0.15,0.25) 0.18(0.14,0.24) 0.02(0.01,0.04) 0.01(0.01,0.02) −7.01(−8.77,−5.21)
Typhoid fever Bermuda 0.20(0.11,0.33) 1.25(0.67,2.05) 0.07(0.03,0.13) 0.64(0.30,1.15) −1.94(−2.24,−1.64) 0.02(0.01,0.03) 0.10(0.07,0.16) 0.00(0.00,0.00) 0.02(0.01,0.02) −3.63(−5.79,−1.41)
Typhoid fever Bolivarian Republic of Venezuela 84.51(53.38,132.51) 0.93(0.59,1.46) 24.82(15.15,36.87) 0.28(0.17,0.42) −3.32(−3.59,−3.05) 7.43(5.00,10.54) 0.08(0.06,0.12) 0.58(0.41,0.85) 0.01(0.00,0.01) −8.21(−10.45,−5.91)
Typhoid fever Bosnia and Herzegovina 0.78(0.45,1.26) 0.05(0.03,0.08) 0.30(0.17,0.47) 0.04(0.03,0.07) −0.56(−0.82,−0.30) 0.68(0.24,1.46) 0.05(0.02,0.10) 0.22(0.08,0.45) 0.03(0.01,0.07) −0.98(−1.30,−0.67)
Typhoid fever Brunei Darussalam 0.08(0.05,0.12) 0.07(0.04,0.10) 0.06(0.04,0.10) 0.05(0.03,0.08) −1.15(−1.24,−1.06) 0.06(0.02,0.16) 0.05(0.01,0.14) 0.04(0.01,0.11) 0.03(0.01,0.09) −1.07(−1.18,−0.96)
Typhoid fever Burkina Faso 117,942.91(81562.26,159557.22) 2084.82(1441.74,2820.42) 78,356.78(59388.39,102746.68) 611.88(463.76,802.34) −3.90(−3.94,−3.87) 142,148.21(66771.62,259840.45) 2512.69(1180.29,4593.08) 113,077.74(52627.58,217833.31) 883.02(410.97,1701.05) −2.98(−3.17,−2.79)
Typhoid fever Canada 0.63(0.27,1.13) 0.01(0.00,0.01) 0.64(0.26,1.10) 0.01(0.00,0.01) 0.09(0.00,0.18) 0.13(0.10,0.17) 0.00(0.00,0.00) 0.03(0.03,0.04) 0.00(0.00,0.00) 0.58(−1.61,2.81)
Typhoid fever Central African Republic 1726.60(1167.68,2424.61) 115.33(77.99,161.95) 1323.08(944.39,1849.88) 45.72(32.63,63.92) −2.77(−2.83,−2.71) 1779.69(763.73,3583.48) 118.87(51.01,239.35) 1702.32(729.15,3413.01) 58.82(25.20,117.93) −1.91(−2.19,−1.62)
Typhoid fever Commonwealth of Dominica 0.82(0.48,1.35) 2.50(1.47,4.12) 0.21(0.11,0.36) 1.10(0.57,1.85) −2.55(−2.75,−2.35) 0.60(0.24,1.27) 1.83(0.75,3.86) 0.17(0.06,0.38) 0.89(0.32,1.97) −2.85(−3.18,−2.51)
Typhoid fever Commonwealth of the Bahamas 0.33(0.19,0.53) 0.30(0.17,0.49) 0.22(0.12,0.37) 0.19(0.11,0.32) −1.17(−1.39,−0.94) 0.01(0.01,0.02) 0.01(0.01,0.02) 0.01(0.01,0.01) 0.01(0.01,0.01) −1.03(−1.36,−0.69)
Typhoid fever Cook Islands 20.80(13.89,28.85) 241.52(161.28,335.10) 3.46(2.29,4.92) 66.83(44.14,94.95) −4.19(−4.25,−4.12) 14.93(4.54,34.18) 173.40(52.74,397.01) 6.78(2.18,14.79) 130.87(42.13,285.39) −3.34(−4.20,−2.47)
Typhoid fever Czech Republic 1.69(1.00,2.51) 0.06(0.03,0.08) 1.46(0.90,2.19) 0.07(0.04,0.10) 1.30(1.09,1.52) 0.76(0.47,1.19) 0.02(0.02,0.04) 0.54(0.24,1.05) 0.02(0.01,0.05) 13.41(9.14,17.86)
Typhoid fever Democratic People’s Republic of Korea 1487.69(979.62,2160.77) 19.10(12.58,27.74) 266.81(175.70,384.12) 4.04(2.66,5.82) −5.10(−5.19,−5.01) 1949.50(805.66,3794.84) 25.03(10.34,48.72) 349.03(152.51,689.04) 5.29(2.31,10.44) −5.01(−5.11,−4.91)
Typhoid fever Democratic Republic of Sao Tome and Principe 392.26(278.93,526.85) 561.31(399.14,753.90) 111.60(77.87,159.51) 109.63(76.49,156.68) −5.24(−5.45,−5.03) 641.98(298.97,1236.84) 918.63(427.81,1769.84) 187.74(81.58,347.85) 184.42(80.14,341.69) −4.60(−5.17,−4.02)
Typhoid fever Democratic Republic of the Congo 23,415.02(16440.70,32124.07) 108.15(75.94,148.38) 18,896.51(12367.24,25970.85) 39.44(25.82,54.21) −3.06(−3.19,−2.92) 22,466.64(10152.21,45170.94) 103.77(46.89,208.64) 17,077.05(7032.94,36429.24) 35.65(14.68,76.04) −2.80(−3.01,−2.58)
Typhoid fever Democratic Republic of Timor−Leste 3274.23(2361.79,4308.90) 805.14(580.77,1059.57) 2014.99(1372.78,2756.68) 293.98(200.28,402.18) −3.30(−3.44,−3.15) 2853.72(1325.67,5455.49) 701.74(325.99,1341.52) 2248.73(1025.13,4219.72) 328.08(149.56,615.63) −2.48(−2.64,−2.32)
Typhoid fever Democratic Socialist Republic of Sri Lanka 27,942.96(14539.90,47810.12) 385.95(200.82,660.35) 9195.26(4877.89,15338.30) 133.27(70.69,222.30) −3.38(−3.52,−3.24) 25,349.92(10862.37,49394.00) 350.13(150.03,682.23) 7251.13(3179.97,14072.91) 105.09(46.09,203.96) −3.80(−4.24,−3.36)
Typhoid fever Dominican Republic 116.66(70.72,179.48) 3.33(2.02,5.12) 65.88(38.95,106.35) 1.69(1.00,2.73) −2.37(−2.63,−2.10) 85.83(35.68,180.69) 2.45(1.02,5.16) 49.04(19.74,108.70) 1.26(0.51,2.79) −2.43(−2.68,−2.18)
Typhoid fever Eastern Republic of Uruguay 1.32(0.69,2.28) 0.12(0.06,0.21) 0.44(0.24,0.82) 0.05(0.03,0.09) −3.36(−3.83,−2.88) 0.03(0.02,0.04) 0.00(0.00,0.00) 0.02(0.01,0.02) 0.00(0.00,0.00) −1.29(−2.39,−0.17)
Typhoid fever Federal Democratic Republic of Ethiopia 196,894.53(135778.71,269816.92) 668.18(460.78,915.65) 107,114.96(75991.90,146464.50) 187.27(132.86,256.07) −4.23(−4.32,−4.13) 223,534.85(94060.50,427573.65) 758.59(319.20,1451.01) 162,172.56(70447.37,305172.28) 283.53(123.16,533.54) −3.22(−3.49,−2.94)
Typhoid fever Federal Democratic Republic of Nepal 217,703.50(150368.30,293123.60) 2103.66(1453.00,2832.44) 55,040.03(39538.18,74884.50) 441.93(317.46,601.26) −5.32(−5.44,−5.19) 206,224.23(100093.54,368481.95) 1992.73(967.20,3560.62) 67,484.81(34286.02,114446.94) 541.85(275.29,918.92) −4.14(−4.36,−3.92)
Typhoid fever Federal Republic of Germany 230.44(139.66,383.11) 1.33(0.81,2.21) 210.38(129.42,337.84) 1.32(0.81,2.12) −0.27(−0.75,0.22) 2.46(1.45,4.22) 0.01(0.01,0.02) 2.12(1.21,3.60) 0.01(0.01,0.02) −0.48(−1.04,0.09)
Typhoid fever Federal Republic of Nigeria 295,822.63(202117.44,399818.75) 609.70(416.57,824.05) 188,504.37(132070.21,256145.19) 147.53(103.36,200.47) −4.72(−4.94,−4.50) 334,290.63(148711.59,642425.07) 688.99(306.50,1324.07) 308,034.40(120650.63,655477.49) 241.08(94.43,513.00) −3.22(−3.32,−3.11)
Typhoid fever Federal Republic of Somalia 24,042.93(17028.04,31857.02) 508.06(359.82,673.18) 18,939.38(12453.01,26644.51) 148.14(97.41,208.41) −3.95(−4.01,−3.89) 21,320.07(9004.98,40361.75) 450.52(190.29,852.89) 17,979.92(6859.52,35757.05) 140.64(53.66,279.69) −3.35(−3.66,−3.04)
Typhoid fever Federated States of Micronesia 238.60(168.49,335.26) 414.98(293.03,583.08) 39.98(27.30,57.57) 96.46(65.88,138.90) −4.57(−4.63,−4.50) 260.27(117.93,506.79) 452.66(205.10,881.40) 44.42(18.40,86.40) 107.17(44.41,208.48) −4.34(−4.45,−4.23)
Typhoid fever Federative Republic of Brazil 1603.31(951.42,2504.38) 2.39(1.42,3.73) 301.50(188.72,453.68) 0.47(0.30,0.71) −5.32(−5.56,−5.07) 1152.04(603.52,2059.92) 1.71(0.90,3.07) 86.79(35.24,182.31) 0.14(0.06,0.29) −7.46(−7.70,−7.21)
Typhoid fever French Republic 194.43(116.77,306.45) 1.20(0.72,1.90) 167.36(95.36,265.98) 1.06(0.61,1.69) −0.13(−0.21,−0.06) 4.23(3.03,5.95) 0.03(0.02,0.04) 1.71(0.95,3.03) 0.01(0.01,0.02) −2.68(−3.46,−1.89)
Typhoid fever Gabonese Republic 504.74(353.14,708.60) 99.32(69.49,139.44) 249.05(173.76,346.95) 30.11(21.01,41.95) −3.53(−3.64,−3.42) 369.75(158.64,787.34) 72.76(31.22,154.93) 226.33(85.91,453.71) 27.37(10.39,54.86) −2.51(−2.74,−2.28)
Typhoid fever Georgia 2.62(1.36,4.97) 0.15(0.08,0.28) 1.13(0.64,1.98) 0.12(0.07,0.21) −0.68(−0.81,−0.56) 0.79(0.49,1.18) 0.04(0.03,0.07) 0.02(0.02,0.04) 0.00(0.00,0.00) −8.99(−10.81,−7.13)
Typhoid fever Grand Duchy of Luxembourg 0.64(0.35,1.10) 0.73(0.40,1.24) 0.87(0.46,1.51) 0.65(0.34,1.12) −0.12(−0.25,0.02) 0.01(0.00,0.01) 0.01(0.01,0.02) 0.01(0.00,0.02) 0.01(0.00,0.01) −0.82(−1.82,0.18)
Typhoid fever Greenland 0.01(0.00,0.01) 0.04(0.02,0.07) 0.01(0.00,0.01) 0.03(0.02,0.05) −0.33(−0.69,0.02) 0.01(0.00,0.02) 0.04(0.01,0.10) 0.01(0.00,0.02) 0.05(0.01,0.13) 0.42(−0.24,1.08)
Typhoid fever Grenada 0.38(0.21,0.63) 0.91(0.49,1.49) 0.08(0.04,0.15) 0.27(0.13,0.51) −3.12(−3.52,−2.72) 0.01(0.01,0.02) 0.03(0.03,0.04) 0.00(0.00,0.00) 0.01(0.01,0.02) −2.36(−2.65,−2.07)
Typhoid fever Guam 128.21(91.39,172.73) 236.80(168.80,319.01) 34.27(22.25,46.82) 70.68(45.89,96.57) −4.05(−4.14,−3.96) 83.33(28.09,186.65) 153.91(51.89,344.73) 19.64(5.84,49.86) 40.50(12.04,102.84) −3.02(−3.44,−2.60)
Typhoid fever Hashemite Kingdom of Jordan 2310.37(1621.29,3167.56) 110.19(77.33,151.08) 1298.42(892.31,1858.84) 26.36(18.12,37.74) −4.59(−4.69,−4.49) 2006.06(914.10,4002.99) 95.68(43.60,190.92) 891.48(389.66,1739.19) 18.10(7.91,35.31) −5.14(−5.44,−4.85)
Typhoid fever Hellenic Republic 0.46(0.24,0.79) 0.02(0.01,0.03) 0.33(0.17,0.57) 0.02(0.01,0.03) 0.67(0.38,0.96) 0.01(0.01,0.02) 0.00(0.00,0.00) 0.01(0.01,0.01) 0.00(0.00,0.00) −1.08(−1.67,−0.49)
Typhoid fever Hungary 1.32(0.77,2.14) 0.05(0.03,0.07) 1.09(0.66,1.84) 0.06(0.04,0.10) 1.32(1.05,1.59) 0.09(0.07,0.11) 0.00(0.00,0.00) 0.02(0.02,0.03) 0.00(0.00,0.00) −2.76(−2.96,−2.57)
Typhoid fever Independent State of Papua New Guinea 33,424.98(22504.46,46076.29) 1570.25(1057.22,2164.59) 25,016.16(17000.21,35679.45) 510.63(347.01,728.29) −3.68(−3.75,−3.62) 31,615.44(14328.21,59771.61) 1485.24(673.11,2807.97) 32,353.53(14718.85,59714.19) 660.40(300.44,1218.89) −2.67(−2.80,−2.54)
Typhoid fever Independent State of Samoa 218.70(146.45,300.96) 238.77(159.89,328.58) 75.22(52.62,102.49) 74.52(52.13,101.53) −3.80(−3.85,−3.75) 233.55(104.53,449.39) 254.99(114.13,490.63) 88.37(37.79,166.82) 87.55(37.44,165.27) −3.55(−3.67,−3.42)
Typhoid fever Ireland 0.21(0.10,0.34) 0.02(0.01,0.03) 0.17(0.08,0.29) 0.01(0.01,0.02) −0.41(−0.64,−0.19) 2.96(1.95,4.41) 0.22(0.15,0.33) 0.64(0.41,0.99) 0.05(0.03,0.07) −4.37(−5.18,−3.56)
Typhoid fever Islamic Republic of Afghanistan 10,360.78(7355.91,14927.99) 185.91(131.99,267.86) 8715.64(5905.52,12092.31) 49.03(33.22,68.02) −4.55(−4.72,−4.39) 13,181.08(5779.18,26113.96) 236.52(103.70,468.58) 11,152.10(5091.37,22486.43) 62.73(28.64,126.49) −3.74(−3.98,−3.49)
Typhoid fever Islamic Republic of Iran 55,697.24(38580.32,75466.11) 176.76(122.44,239.50) 9402.97(6482.27,13090.91) 36.37(25.07,50.63) −4.67(−5.02,−4.32) 51,049.39(23015.50,103568.88) 162.01(73.04,328.69) 5631.01(2540.48,10563.09) 21.78(9.83,40.86) −5.15(−5.57,−4.72)
Typhoid fever Islamic Republic of Mauritania 6793.32(4671.65,9054.39) 599.10(411.99,798.50) 3486.75(2336.01,4884.28) 149.51(100.16,209.43) −4.50(−4.63,−4.38) 7961.84(3664.03,14680.99) 702.15(323.13,1294.71) 5276.41(2443.63,9677.28) 226.24(104.78,414.95) −3.82(−4.10,−3.55)
Typhoid fever Islamic Republic of Pakistan 730,325.29(513413.86,995751.24) 1197.97(842.17,1633.36) 364,534.03(248631.96,496634.14) 333.75(227.64,454.69) −4.09(−4.25,−3.94) 701,848.21(333558.76,1242963.02) 1151.26(547.15,2038.87) 610,567.65(284188.98,1103567.07) 559.01(260.19,1010.37) −1.87(−2.18,−1.56)
Typhoid fever Jamaica 23.74(14.96,37.37) 2.17(1.37,3.42) 4.57(2.63,7.48) 0.56(0.32,0.92) −4.59(−4.90,−4.27) 11.62(8.70,14.75) 1.06(0.80,1.35) 0.05(0.03,0.08) 0.01(0.00,0.01) −8.59(−10.73,−6.40)
Typhoid fever Japan 38.32(20.05,66.26) 0.11(0.06,0.20) 29.39(14.41,54.34) 0.14(0.07,0.26) 0.67(0.44,0.91) 3.56(3.07,4.09) 0.01(0.01,0.01) 0.51(0.34,0.76) 0.00(0.00,0.00) −4.68(−6.13,−3.21)
Typhoid fever Kingdom of Bahrain 233.37(168.00,321.09) 116.63(83.96,160.47) 107.25(73.03,148.69) 26.58(18.10,36.85) −4.62(−4.74,−4.50) 175.03(54.24,438.51) 87.47(27.11,219.15) 59.18(18.48,142.55) 14.66(4.58,35.33) −5.41(−5.53,−5.30)
Typhoid fever Kingdom of Belgium 0.29(0.13,0.47) 0.01(0.01,0.02) 0.32(0.16,0.55) 0.01(0.01,0.02) 0.35(0.17,0.53) 0.02(0.01,0.02) 0.00(0.00,0.00) 0.01(0.01,0.01) 0.00(0.00,0.00) −2.33(−3.62,−1.02)
Typhoid fever Kingdom of Bhutan 7424.81(5338.84,10236.87) 2179.83(1567.42,3005.42) 1395.38(981.29,1909.41) 547.26(384.86,748.86) −4.61(−4.72,−4.50) 6078.76(1963.64,12614.46) 1784.65(576.50,3703.45) 2418.86(1214.77,4174.61) 948.66(476.43,1637.26) −2.47(−2.87,−2.08)
Typhoid fever Kingdom of Cambodia 45,103.30(29984.91,61813.60) 792.20(526.66,1085.70) 16,000.59(10886.74,22169.01) 241.30(164.18,334.32) −3.87(−3.94,−3.79) 41,112.32(19481.39,79813.42) 722.10(342.17,1401.85) 19,571.16(9223.82,37320.15) 295.14(139.10,562.80) −2.88(−2.95,−2.82)
Typhoid fever Kingdom of Denmark 1.58(0.97,2.66) 0.13(0.08,0.21) 1.31(0.79,2.23) 0.10(0.06,0.17) −0.75(−1.04,−0.47) 0.02(0.01,0.03) 0.00(0.00,0.00) 0.03(0.02,0.04) 0.00(0.00,0.00) 1.77(0.68,2.87)
Typhoid fever Kingdom of Eswatini 12.41(8.05,17.80) 2.60(1.69,3.73) 12.42(7.86,17.70) 2.32(1.47,3.31) −0.24(−0.31,−0.16) 13.43(5.31,27.28) 2.81(1.11,5.72) 18.83(7.52,39.16) 3.52(1.41,7.32) 1.01(0.82,1.20)
Typhoid fever Kingdom of Lesotho 23.21(15.02,32.49) 2.77(1.79,3.88) 21.32(14.31,29.44) 2.54(1.71,3.51) −0.14(−0.21,−0.08) 19.01(7.90,37.50) 2.27(0.94,4.48) 25.76(11.17,52.70) 3.07(1.33,6.28) 1.64(1.40,1.88)
Typhoid fever Kingdom of Morocco 16,228.27(11101.76,23103.84) 130.04(88.96,185.13) 3794.66(2482.93,5350.86) 29.38(19.22,41.43) −4.82(−4.89,−4.75) 20,179.72(8635.23,39489.50) 161.70(69.19,316.43) 4483.79(1843.59,8351.32) 34.72(14.27,64.66) −4.50(−4.68,−4.31)
Typhoid fever Kingdom of Norway 8.61(3.45,16.46) 0.77(0.31,1.48) 5.18(2.03,10.45) 0.42(0.16,0.84) −1.65(−1.77,−1.53) 0.09(0.04,0.18) 0.01(0.00,0.02) 0.05(0.02,0.11) 0.00(0.00,0.01) −1.58(−1.79,−1.36)
Typhoid fever Kingdom of Saudi Arabia 13,078.24(9104.21,18653.66) 159.27(110.87,227.17) 2761.67(1845.74,3904.50) 27.25(18.21,38.53) −5.36(−5.66,−5.06) 8986.12(2624.88,22376.73) 109.43(31.97,272.51) 1625.92(482.05,4055.43) 16.05(4.76,40.02) −5.82(−6.07,−5.56)
Typhoid fever Kingdom of Spain 57.73(35.62,90.65) 0.52(0.32,0.81) 43.14(25.38,71.05) 0.49(0.29,0.81) 0.32(0.09,0.55) 3.76(3.01,4.57) 0.03(0.03,0.04) 0.45(0.25,0.78) 0.01(0.00,0.01) −4.71(−6.06,−3.34)
Typhoid fever Kingdom of Sweden 5.93(2.95,10.62) 0.28(0.14,0.50) 5.59(2.72,9.87) 0.23(0.11,0.41) −0.34(−0.67,−0.00) 0.09(0.05,0.14) 0.00(0.00,0.01) 0.22(0.17,0.29) 0.01(0.01,0.01) 3.04(1.72,4.38)
Typhoid fever Kingdom of Thailand 95,475.00(65066.83,123527.18) 419.73(286.05,543.05) 23,046.12(16006.90,31601.94) 168.86(117.28,231.55) −2.78(−2.83,−2.73) 67,131.76(30949.51,136056.51) 295.13(136.06,598.13) 17,008.73(7675.80,30770.76) 124.62(56.24,225.46) −2.83(−2.98,−2.68)
Typhoid fever Kingdom of the Netherlands 1.86(1.11,3.11) 0.05(0.03,0.08) 1.74(0.97,3.00) 0.05(0.03,0.08) −0.21(−0.36,−0.07) 0.08(0.06,0.10) 0.00(0.00,0.00) 0.16(0.12,0.20) 0.00(0.00,0.01) −3.10(−7.12,1.11)
Typhoid fever Kingdom of Tonga 139.15(107.00,176.97) 260.77(200.52,331.64) 40.51(27.98,54.89) 81.70(56.42,110.71) −3.36(−3.58,−3.14) 101.07(47.98,192.51) 189.41(89.92,360.77) 41.62(18.82,79.60) 83.94(37.95,160.54) −2.50(−2.77,−2.24)
Typhoid fever Kyrgyz Republic 6.00(2.74,10.64) 0.28(0.13,0.50) 6.99(4.10,11.68) 0.25(0.15,0.41) −0.89(−1.43,−0.34) 0.15(0.10,0.22) 0.01(0.00,0.01) 0.11(0.07,0.16) 0.00(0.00,0.01) −2.04(−7.07,3.26)
Typhoid fever Lao People’s Democratic Republic 17,466.08(11797.81,24125.93) 769.95(520.08,1063.53) 8191.45(5668.68,11691.96) 273.82(189.49,390.84) −3.39(−3.48,−3.31) 14,232.68(6271.30,27590.27) 627.41(276.45,1216.24) 9370.04(4198.14,18874.73) 313.22(140.33,630.94) −2.13(−2.23,−2.04)
Typhoid fever Lebanese Republic 1652.76(1071.15,2343.37) 123.42(79.99,174.99) 453.41(301.37,642.86) 27.21(18.09,38.58) −4.83(−5.01,−4.65) 1059.82(430.83,2111.61) 79.14(32.17,157.69) 258.67(102.42,506.10) 15.52(6.15,30.37) −5.02(−5.27,−4.77)
Typhoid fever Malaysia 36,550.88(24584.93,53138.03) 438.10(294.68,636.92) 18,389.80(12765.27,25166.78) 179.32(124.48,245.40) −2.79(−2.86,−2.72) 23,302.67(10280.53,42577.63) 279.31(123.22,510.34) 10,747.49(5071.30,19295.09) 104.80(49.45,188.15) −2.70(−2.91,−2.49)
Typhoid fever Mongolia 2.74(1.42,5.23) 0.24(0.12,0.46) 3.01(1.65,5.27) 0.23(0.13,0.40) −0.16(−0.26,−0.05) 2.73(1.05,6.06) 0.24(0.09,0.53) 2.54(1.00,5.24) 0.19(0.08,0.40) −0.00(−0.31,0.31)
Typhoid fever Montenegro 0.12(0.07,0.18) 0.05(0.03,0.09) 0.08(0.05,0.13) 0.06(0.03,0.09) 0.03(−0.12,0.17) 0.16(0.06,0.32) 0.07(0.03,0.15) 0.06(0.02,0.13) 0.04(0.01,0.09) −0.79(−1.25,−0.33)
Typhoid fever New Zealand 4.76(2.12,9.16) 0.43(0.19,0.83) 5.74(2.35,11.86) 0.44(0.18,0.91) 0.46(0.17,0.76) 0.14(0.11,0.19) 0.01(0.01,0.02) 0.06(0.03,0.14) 0.00(0.00,0.01) −1.88(−2.72,−1.04)
Typhoid fever North Macedonia 0.32(0.18,0.51) 0.05(0.03,0.07) 0.20(0.11,0.33) 0.04(0.02,0.07) 0.16(−0.00,0.33) 0.39(0.14,0.85) 0.06(0.02,0.12) 0.16(0.06,0.36) 0.04(0.01,0.08) −0.09(−0.43,0.25)
Typhoid fever Northern Mariana Islands 37.87(26.39,52.25) 233.55(162.73,322.20) 10.04(7.04,14.10) 66.94(46.91,93.99) −4.30(−4.49,−4.10) 19.87(6.57,45.83) 122.54(40.54,282.61) 4.78(1.56,12.02) 31.87(10.38,80.14) −4.72(−5.02,−4.42)
Typhoid fever Palestine 1873.86(1327.38,2562.24) 156.99(111.21,214.67) 689.21(484.84,960.62) 28.62(20.14,39.90) −5.45(−5.67,−5.22) 2069.11(944.66,3989.33) 173.35(79.15,334.23) 771.97(338.94,1418.76) 32.06(14.08,58.92) −5.03(−5.26,−4.80)
Typhoid fever People’s Democratic Republic of Algeria 16,143.75(11120.53,23147.52) 119.44(82.27,171.25) 5010.26(3481.60,7258.64) 30.46(21.17,44.13) −4.18(−4.42,−3.93) 14,388.31(6163.55,30174.91) 106.45(45.60,223.24) 4308.50(1921.12,8649.03) 26.19(11.68,52.58) −4.13(−4.29,−3.96)
Typhoid fever People’s Republic of Bangladesh 1,347,243.14(1037730.40,1768530.57) 2232.04(1719.26,2930.01) 320,790.58(240520.24,428440.53) 525.98(394.37,702.49) −4.52(−4.54,−4.50) 1,542,948.66(784785.41,2702889.37) 2556.27(1300.19,4478.00) 499,186.76(252342.53,841278.60) 818.49(413.75,1379.39) −3.38(−3.48,−3.28)
Typhoid fever People’s Republic of China 98,475.83(68468.18,138920.39) 22.13(15.38,31.22) 30,648.74(22133.78,41022.65) 9.17(6.62,12.27) −2.43(−2.69,−2.17) 111,723.28(48050.17,226828.29) 25.10(10.80,50.97) 23,257.10(10171.36,43836.94) 6.96(3.04,13.11) −3.25(−3.59,−2.90)
Typhoid fever Plurinational State of Bolivia 38.87(22.27,64.18) 1.16(0.66,1.92) 28.25(15.91,46.53) 0.62(0.35,1.02) −2.20(−2.39,−2.00) 45.05(19.53,93.21) 1.35(0.58,2.78) 32.16(12.84,68.66) 0.71(0.28,1.51) −2.14(−2.38,−1.90)
Typhoid fever Portuguese Republic 55.00(34.23,87.84) 1.85(1.15,2.95) 22.21(13.37,35.84) 1.16(0.70,1.87) −1.32(−1.47,−1.17) 15.02(11.64,18.93) 0.50(0.39,0.63) 0.24(0.14,0.40) 0.01(0.01,0.02) −8.01(−9.87,−6.11)
Typhoid fever Principality of Andorra 0.01(0.01,0.02) 0.11(0.06,0.18) 0.01(0.01,0.02) 0.08(0.05,0.14) −0.74(−1.07,−0.41) 0.02(0.01,0.05) 0.13(0.04,0.34) 0.01(0.00,0.02) 0.04(0.01,0.11) −2.98(−3.59,−2.37)
Typhoid fever Principality of Monaco 0.01(0.00,0.01) 0.12(0.08,0.21) 0.01(0.00,0.01) 0.10(0.06,0.17) −0.41(−0.50,−0.32) 0.01(0.00,0.01) 0.12(0.03,0.31) 0.01(0.00,0.04) 0.21(0.05,0.58) −0.34(−1.23,0.56)
Typhoid fever Puerto Rico 4.37(2.34,7.42) 0.33(0.18,0.56) 1.51(0.78,2.56) 0.23(0.12,0.39) −0.94(−1.10,−0.77) 0.05(0.03,0.08) 0.00(0.00,0.01) 0.02(0.01,0.03) 0.00(0.00,0.00) −0.11(−0.86,0.65)
Typhoid fever Republic of Albania 1.24(0.71,1.90) 0.09(0.05,0.13) 0.36(0.21,0.57) 0.06(0.03,0.09) −1.64(−1.96,−1.32) 0.96(0.37,2.02) 0.07(0.03,0.14) 0.31(0.12,0.64) 0.05(0.02,0.10) −1.20(−1.51,−0.89)
Typhoid fever Republic of Angola 5887.86(3790.83,8007.37) 102.11(65.74,138.87) 6697.65(4478.34,9462.17) 35.86(23.98,50.67) −3.19(−3.28,−3.09) 4576.56(1863.22,9793.11) 79.37(32.31,169.84) 5793.78(2373.70,13166.53) 31.02(12.71,70.50) −2.53(−2.76,−2.29)
Typhoid fever Republic of Armenia 36.61(20.55,58.59) 2.76(1.55,4.41) 7.41(4.48,11.94) 0.97(0.59,1.56) −3.69(−4.05,−3.33) 2.36(1.20,4.06) 0.18(0.09,0.31) 0.30(0.18,0.48) 0.04(0.02,0.06) −4.05(−5.54,−2.54)
Typhoid fever Republic of Austria 0.70(0.42,1.10) 0.04(0.02,0.06) 0.50(0.28,0.80) 0.03(0.02,0.05) −0.70(−0.79,−0.60) 0.10(0.06,0.14) 0.01(0.00,0.01) 0.01(0.01,0.02) 0.00(0.00,0.00) −5.31(−6.91,−3.68)
Typhoid fever Republic of Azerbaijan 4.94(2.68,8.74) 0.16(0.09,0.28) 4.24(2.26,7.56) 0.14(0.07,0.25) −0.81(−1.15,−0.47) 3.63(1.28,7.89) 0.12(0.04,0.25) 3.06(1.01,6.91) 0.10(0.03,0.23) −0.80(−1.13,−0.48)
Typhoid fever Republic of Belarus 2.56(1.47,4.00) 0.08(0.05,0.13) 1.13(0.62,1.85) 0.06(0.03,0.09) −0.18(−0.59,0.24) 0.53(0.23,0.98) 0.02(0.01,0.03) 0.04(0.03,0.06) 0.00(0.00,0.00) −6.79(−7.00,−6.57)
Typhoid fever Republic of Benin 18,759.41(12785.73,25917.59) 653.71(445.54,903.15) 12,269.60(7934.99,17424.20) 163.24(105.57,231.82) −4.41(−4.45,−4.37) 26,858.45(11441.55,50389.49) 935.93(398.70,1755.92) 21,283.11(8653.57,43865.33) 283.16(115.13,583.60) −3.78(−3.90,−3.67)
Typhoid fever Republic of Botswana 19.60(12.67,27.50) 2.65(1.71,3.71) 19.14(13.15,25.50) 2.09(1.43,2.78) −0.65(−0.72,−0.59) 15.48(6.50,31.78) 2.09(0.88,4.29) 22.16(8.83,44.98) 2.42(0.96,4.90) 0.78(0.57,0.99)
Typhoid fever Republic of Bulgaria 0.82(0.48,1.22) 0.03(0.02,0.05) 0.50(0.29,0.75) 0.04(0.02,0.06) 1.09(0.87,1.32) 0.17(0.12,0.25) 0.01(0.01,0.01) 0.04(0.03,0.07) 0.00(0.00,0.01) −2.69(−3.02,−2.37)
Typhoid fever Republic of Burundi 16,238.55(11956.18,20996.76) 514.67(378.94,665.48) 10,522.76(7134.32,14852.63) 144.65(98.07,204.17) −4.00(−4.06,−3.93) 17,187.64(7721.04,33414.26) 544.75(244.71,1059.05) 11,775.50(4839.84,24364.93) 161.87(66.53,334.93) −3.11(−3.46,−2.77)
Typhoid fever Republic of Cabo Verde 1101.53(723.33,1575.69) 566.42(371.94,810.24) 213.16(147.11,293.25) 110.59(76.33,152.14) −5.42(−5.53,−5.31) 1156.52(481.36,2128.82) 594.70(247.52,1094.67) 332.27(155.41,610.45) 172.39(80.63,316.71) −4.04(−4.36,−3.73)
Typhoid fever Republic of Cameroon 34,287.69(22290.49,46082.60) 577.52(375.45,776.18) 25,959.99(17764.92,36107.78) 153.58(105.10,213.62) −4.19(−4.25,−4.13) 46,714.36(21016.23,91755.40) 786.83(353.98,1545.47) 41,233.16(17187.20,79247.77) 243.94(101.68,468.84) −3.30(−3.50,−3.10)
Typhoid fever Republic of Chad 22,976.00(15297.75,31627.47) 651.75(433.94,897.16) 20,149.56(13920.50,27429.09) 184.02(127.13,250.50) −4.14(−4.23,−4.05) 24,542.17(10843.05,45941.22) 696.18(307.58,1303.19) 28,074.03(12022.27,52473.26) 256.39(109.80,479.23) −3.01(−3.10,−2.93)
Typhoid fever Republic of Chile 153.68(90.54,250.35) 2.91(1.72,4.75) 48.68(27.48,75.37) 0.99(0.56,1.54) −3.37(−3.63,−3.12) 328.64(268.56,402.26) 6.23(5.09,7.63) 1.01(0.74,1.43) 0.02(0.02,0.03) −15.87(−17.87,−13.83)
Typhoid fever Republic of Colombia 811.95(572.05,1114.20) 5.39(3.80,7.40) 218.96(145.38,314.24) 1.50(1.00,2.16) −3.92(−4.24,−3.60) 1457.90(1216.87,1704.49) 9.69(8.08,11.32) 16.99(12.83,22.39) 0.12(0.09,0.15) −14.34(−15.85,−12.81)
Typhoid fever Republic of Costa Rica 0.87(0.45,1.44) 0.06(0.03,0.10) 0.38(0.18,0.65) 0.03(0.01,0.05) −2.25(−2.37,−2.13) 0.02(0.01,0.02) 0.00(0.00,0.00) 0.01(0.01,0.01) 0.00(0.00,0.00) −2.21(−3.04,−1.37)
Typhoid fever Republic of Croatia 0.14(0.04,0.27) 0.01(0.00,0.02) 0.11(0.05,0.19) 0.01(0.01,0.02) 0.73(0.55,0.90) 0.01(0.00,0.01) 0.00(0.00,0.00) 0.00(0.00,0.00) 0.00(0.00,0.00) −3.18(−3.43,−2.93)
Typhoid fever Republic of Cuba 83.57(51.63,129.19) 2.29(1.41,3.54) 16.37(9.02,26.44) 0.68(0.38,1.10) −3.75(−4.02,−3.48) 3.33(2.08,5.02) 0.09(0.06,0.14) 0.19(0.11,0.30) 0.01(0.00,0.01) −6.39(−7.35,−5.43)
Typhoid fever Republic of Cyprus 0.32(0.19,0.54) 0.12(0.07,0.21) 0.33(0.20,0.55) 0.11(0.07,0.19) 0.18(−0.00,0.36) 0.29(0.09,0.79) 0.11(0.03,0.31) 0.18(0.05,0.49) 0.06(0.02,0.17) −1.31(−1.47,−1.15)
Typhoid fever Republic of C么te d’Ivoire 39,541.73(27346.89,53687.08) 571.54(395.27,775.99) 21,186.45(14978.65,30806.49) 147.29(104.13,214.16) −4.25(−4.33,−4.18) 46,764.15(20851.24,89645.78) 675.93(301.38,1295.74) 32,839.16(14347.37,65102.17) 228.29(99.74,452.58) −3.17(−3.52,−2.82)
Typhoid fever Republic of Djibouti 1022.01(712.00,1395.49) 455.70(317.47,622.23) 640.05(440.72,883.39) 121.14(83.41,167.19) −4.18(−4.26,−4.11) 1095.35(481.46,2057.42) 488.40(214.67,917.37) 1003.09(416.25,1941.07) 189.85(78.78,367.37) −2.77(−3.15,−2.39)
Typhoid fever Republic of Ecuador 65.06(38.75,102.95) 1.31(0.78,2.08) 34.04(19.05,54.87) 0.51(0.29,0.83) −2.93(−3.20,−2.66) 2796.68(2330.05,3223.75) 56.41(47.00,65.03) 5.74(4.29,7.48) 0.09(0.06,0.11) −24.71(−28.06,−21.21)
Typhoid fever Republic of El Salvador 65.48(38.82,102.04) 2.38(1.41,3.70) 20.11(11.66,32.30) 0.84(0.49,1.36) −2.77(−3.43,−2.10) 68.76(30.72,135.81) 2.50(1.12,4.93) 22.14(9.15,45.57) 0.93(0.38,1.91) −2.45(−3.14,−1.77)
Typhoid fever Republic of Equatorial Guinea 275.27(182.60,385.94) 114.71(76.09,160.82) 192.64(129.87,273.13) 25.01(16.86,35.47) −4.99(−5.07,−4.92) 166.04(46.04,422.45) 69.19(19.18,176.04) 121.28(26.72,302.89) 15.75(3.47,39.33) −4.85(−5.02,−4.68)
Typhoid fever Republic of Estonia 1.20(0.71,1.96) 0.26(0.16,0.43) 0.58(0.33,0.95) 0.21(0.12,0.34) 0.18(−0.29,0.65) 0.37(0.26,0.54) 0.08(0.06,0.12) 0.03(0.02,0.04) 0.01(0.01,0.01) −5.24(−5.68,−4.79)
Typhoid fever Republic of Fiji 1034.83(722.75,1398.93) 288.49(201.49,389.99) 282.81(206.21,391.03) 80.66(58.81,111.52) −3.99(−4.06,−3.93) 790.10(344.18,1467.55) 220.26(95.95,409.12) 273.06(120.74,539.32) 77.88(34.43,153.82) −3.21(−3.35,−3.06)
Typhoid fever Republic of Finland 0.16(0.08,0.27) 0.01(0.01,0.02) 0.13(0.06,0.22) 0.01(0.01,0.02) 0.00(−0.11,0.12) 0.02(0.01,0.02) 0.00(0.00,0.00) 0.01(0.01,0.01) 0.00(0.00,0.00) −2.24(−2.87,−1.61)
Typhoid fever Republic of Ghana 64,561.35(46887.98,85701.26) 781.65(567.68,1037.60) 38,417.21(28259.51,50298.31) 235.49(173.22,308.31) −4.15(−4.32,−3.97) 70,662.16(31532.80,138136.29) 855.52(381.77,1672.43) 55,177.38(26976.00,102786.86) 338.22(165.35,630.05) −3.06(−3.26,−2.86)
Typhoid fever Republic of Guatemala 3455.85(2603.13,4355.48) 70.37(53.01,88.69) 771.55(609.50,973.23) 11.66(9.21,14.71) −5.80(−5.93,−5.67) 6505.28(5744.04,7400.64) 132.47(116.97,150.70) 567.39(431.80,757.22) 8.58(6.53,11.45) −7.57(−8.62,−6.50)
Typhoid fever Republic of Guinea 20,639.14(15031.12,31402.60) 627.87(457.26,955.30) 11,728.71(7773.60,16591.91) 157.13(104.14,222.28) −4.49(−4.56,−4.42) 28,409.87(11709.05,56809.61) 864.26(356.20,1728.22) 16,494.61(7103.78,33351.95) 220.98(95.17,446.81) −4.06(−4.20,−3.91)
Typhoid fever Republic of Guinea−Bissau 591.71(413.56,855.02) 100.61(70.32,145.39) 280.40(201.47,386.25) 25.07(18.01,34.53) −4.40(−4.50,−4.31) 784.91(345.88,1593.95) 133.47(58.81,271.04) 400.47(165.90,783.91) 35.80(14.83,70.08) −3.66(−3.96,−3.36)
Typhoid fever Republic of Guyana 144.50(103.76,202.94) 37.87(27.19,53.18) 30.80(20.81,44.05) 10.97(7.41,15.69) −3.29(−3.69,−2.90) 326.54(248.07,411.33) 85.57(65.01,107.79) 0.97(0.70,1.39) 0.34(0.25,0.50) −17.10(−19.41,−14.72)
Typhoid fever Republic of Haiti 4043.45(2757.14,5693.82) 120.83(82.39,170.15) 1502.03(1020.81,2125.11) 26.78(18.20,37.90) −4.49(−4.63,−4.35) 5930.58(2423.76,12398.54) 177.22(72.43,370.50) 2354.21(1045.75,4955.07) 41.98(18.65,88.36) −4.05(−4.21,−3.89)
Typhoid fever Republic of Honduras 35.95(20.95,56.90) 1.32(0.77,2.10) 27.95(15.69,46.11) 0.64(0.36,1.06) −2.01(−2.19,−1.83) 38.91(17.75,77.56) 1.43(0.65,2.86) 29.27(11.05,63.51) 0.67(0.25,1.46) −2.02(−2.15,−1.88)
Typhoid fever Republic of Iceland 0.51(0.29,0.86) 0.60(0.34,1.01) 0.28(0.14,0.49) 0.31(0.16,0.55) −1.71(−2.02,−1.40) 0.04(0.03,0.04) 0.04(0.03,0.05) 0.02(0.01,0.02) 0.02(0.01,0.03) −2.15(−2.78,−1.51)
Typhoid fever Republic of India 8,644,992.64(6112720.45,11924221.43) 2106.40(1489.40,2905.40) 2,629,159.08(1821594.32,3600341.73) 525.23(363.90,719.25) −4.71(−5.07,−4.36) 6,647,305.07(3134953.37,11257910.36) 1619.65(763.85,2743.05) 2,556,283.11(1309189.61,4349580.02) 510.67(261.54,868.92) −3.75(−4.04,−3.45)
Typhoid fever Republic of Indonesia 1,172,699.39(823855.54,1565123.34) 1340.79(941.94,1789.46) 283,107.91(196203.84,386271.34) 313.80(217.48,428.15) −4.57(−4.63,−4.52) 1,014,622.21(518306.70,1843379.45) 1160.05(592.60,2107.60) 324,592.06(155533.42,570138.08) 359.79(172.40,631.96) −3.70(−3.78,−3.63)
Typhoid fever Republic of Iraq 13,835.36(9168.08,19362.21) 134.34(89.02,188.01) 5095.98(3305.85,7293.74) 28.89(18.74,41.35) −4.80(−4.86,−4.75) 11,273.48(4669.14,22860.78) 109.47(45.34,221.98) 3554.57(1468.46,6877.37) 20.15(8.33,38.99) −5.08(−5.17,−4.99)
Typhoid fever Republic of Italy 49.26(28.80,78.18) 0.36(0.21,0.57) 70.41(40.19,114.55) 0.67(0.38,1.09) 2.84(2.20,3.49) 4.14(3.52,4.85) 0.03(0.03,0.04) 0.73(0.41,1.29) 0.01(0.00,0.01) −3.36(−5.53,−1.15)
Typhoid fever Republic of Kazakhstan 101.25(63.03,155.67) 1.52(0.95,2.34) 40.92(21.62,67.32) 0.61(0.32,1.00) −3.09(−3.40,−2.78) 63.90(42.65,91.31) 0.96(0.64,1.37) 0.77(0.52,1.11) 0.01(0.01,0.02) −12.75(−14.88,−10.57)
Typhoid fever Republic of Kenya 146,332.55(101627.23,195227.91) 1061.01(736.87,1415.53) 73,823.34(51943.29,98522.77) 300.09(211.15,400.49) −3.90(−4.00,−3.80) 140,473.80(69302.98,258041.03) 1018.53(502.49,1870.97) 95,370.69(46071.72,166826.14) 387.68(187.28,678.14) −2.28(−2.64,−1.92)
Typhoid fever Republic of Kiribati 135.71(93.02,191.36) 370.25(253.79,522.07) 54.10(38.29,74.56) 101.22(71.65,139.51) −4.00(−4.09,−3.91) 143.71(62.04,267.05) 392.09(169.26,728.59) 71.01(31.69,133.86) 132.87(59.30,250.46) −3.46(−3.63,−3.29)
Typhoid fever Republic of Korea 7.83(4.93,12.17) 0.05(0.03,0.08) 3.18(1.90,5.11) 0.04(0.02,0.06) −0.75(−0.93,−0.57) 6.21(1.85,15.39) 0.04(0.01,0.10) 2.51(0.71,6.17) 0.03(0.01,0.07) −0.42(−0.63,−0.20)
Typhoid fever Republic of Latvia 0.21(0.07,0.38) 0.03(0.01,0.05) 0.07(0.02,0.13) 0.02(0.01,0.03) −1.04(−1.28,−0.80) 0.59(0.43,0.79) 0.08(0.06,0.11) 0.03(0.02,0.04) 0.01(0.01,0.01) −5.90(−6.34,−5.45)
Typhoid fever Republic of Liberia 8006.92(5443.54,11104.48) 586.09(398.45,812.82) 4179.67(2769.16,5946.86) 149.81(99.25,213.15) −4.42(−4.57,−4.27) 12,628.70(5490.24,24341.25) 924.39(401.87,1781.72) 5406.87(2311.51,10917.23) 193.79(82.85,391.29) −4.67(−5.11,−4.24)
Typhoid fever Republic of Lithuania 0.37(0.20,0.58) 0.03(0.02,0.05) 0.15(0.09,0.25) 0.03(0.02,0.05) −0.13(−0.22,−0.04) 0.16(0.10,0.23) 0.01(0.01,0.02) 0.00(0.00,0.00) 0.00(0.00,0.00) −7.73(−9.90,−5.51)
Typhoid fever Republic of Madagascar 33,538.49(21258.04,46327.94) 498.64(316.06,688.79) 20,662.69(14082.04,27242.81) 138.27(94.23,182.30) −3.92(−3.99,−3.84) 32,707.05(14838.95,58799.79) 486.28(220.62,874.22) 24,787.47(11290.93,46778.40) 165.87(75.56,313.03) −3.12(−3.27,−2.98)
Typhoid fever Republic of Malawi 3039.05(2306.11,3935.75) 54.53(41.38,70.62) 3653.50(2840.16,4579.07) 34.50(26.82,43.24) −2.89(−3.37,−2.42) 3530.67(1524.12,7331.83) 63.35(27.35,131.55) 4932.38(2298.17,9418.81) 46.57(21.70,88.93) −1.84(−2.35,−1.33)
Typhoid fever Republic of Maldives 917.01(611.41,1245.70) 714.50(476.39,970.60) 263.47(188.07,346.70) 202.19(144.33,266.07) −3.90(−4.10,−3.69) 678.97(312.73,1309.95) 529.03(243.67,1020.66) 255.03(116.73,476.96) 195.72(89.58,366.03) −2.99(−3.26,−2.72)
Typhoid fever Republic of Mali 30,336.18(19962.23,41672.33) 613.36(403.61,842.57) 24,335.99(16763.00,33361.35) 170.98(117.77,234.39) −4.24(−4.31,−4.16) 38,423.92(15911.85,73182.02) 776.89(321.72,1479.66) 33,176.60(14119.96,63141.02) 233.09(99.21,443.62) −3.74(−3.91,−3.56)
Typhoid fever Republic of Malta 0.07(0.04,0.12) 0.06(0.03,0.10) 0.04(0.02,0.07) 0.05(0.03,0.08) 0.05(−0.11,0.22) 0.03(0.02,0.04) 0.03(0.02,0.03) 0.01(0.01,0.01) 0.01(0.01,0.02) −2.77(−3.20,−2.33)
Typhoid fever Republic of Mauritius 296.82(208.08,423.40) 68.90(48.30,98.28) 83.10(57.75,114.66) 27.99(19.45,38.62) −3.01(−3.08,−2.94) 293.95(132.83,560.52) 68.23(30.83,130.11) 75.84(35.21,139.59) 25.54(11.86,47.02) −3.74(−3.93,−3.55)
Typhoid fever Republic of Moldova 2.22(1.36,3.75) 0.14(0.09,0.24) 0.75(0.47,1.19) 0.11(0.07,0.17) −0.16(−0.43,0.10) 0.12(0.10,0.15) 0.01(0.01,0.01) 0.02(0.01,0.03) 0.00(0.00,0.00) −2.50(−2.89,−2.10)
Typhoid fever Republic of Mozambique 38,545.29(27954.87,53538.73) 509.14(369.25,707.18) 25,202.36(16784.57,35986.51) 141.95(94.54,202.69) −4.06(−4.13,−3.99) 56,432.83(24636.29,113020.65) 745.41(325.42,1492.87) 41,117.99(17601.51,87613.91) 231.60(99.14,493.48) −3.28(−3.48,−3.07)
Typhoid fever Republic of Namibia 19.36(13.35,27.30) 2.54(1.75,3.58) 22.60(15.33,33.48) 2.11(1.43,3.12) −0.49(−0.55,−0.43) 12.32(4.95,25.19) 1.62(0.65,3.31) 24.42(9.25,50.50) 2.28(0.86,4.71) 1.42(1.15,1.69)
Typhoid fever Republic of Nauru 15.46(10.57,21.20) 296.76(202.91,406.97) 4.05(2.83,5.74) 78.93(55.23,111.88) −4.27(−4.41,−4.12) 15.59(7.06,31.07) 299.20(135.41,596.26) 4.82(1.98,9.95) 93.90(38.64,194.02) −3.73(−3.88,−3.58)
Typhoid fever Republic of Nicaragua 48.51(29.55,76.44) 2.16(1.31,3.40) 19.93(11.62,32.81) 0.77(0.45,1.26) −3.47(−3.68,−3.25) 52.54(23.24,101.05) 2.33(1.03,4.49) 18.98(8.21,39.23) 0.73(0.32,1.51) −2.97(−3.27,−2.68)
Typhoid fever Republic of Niue 2.65(1.84,3.81) 258.95(180.11,372.32) 0.36(0.24,0.51) 68.90(45.90,97.37) −4.10(−4.15,−4.06) 2.83(1.21,5.55) 276.81(117.89,543.34) 2.32(1.05,4.38) 438.59(198.19,829.84) −2.10(−3.49,−0.68)
Typhoid fever Republic of Palau 57.10(40.33,79.37) 926.14(654.11,1287.39) 11.96(8.20,16.49) 270.10(185.25,372.46) −3.96(−4.03,−3.88) 43.82(20.60,82.72) 710.75(334.07,1341.80) 9.71(4.35,18.15) 219.25(98.23,409.81) −3.76(−3.85,−3.67)
Typhoid fever Republic of Panama 0.38(0.18,0.62) 0.03(0.02,0.06) 0.38(0.17,0.65) 0.03(0.01,0.04) −0.83(−0.97,−0.68) 0.04(0.03,0.06) 0.00(0.00,0.01) 0.01(0.01,0.01) 0.00(0.00,0.00) −3.85(−4.98,−2.70)
Typhoid fever Republic of Paraguay 110.03(66.25,172.10) 5.32(3.20,8.32) 20.74(10.92,34.67) 0.78(0.41,1.30) −6.02(−6.74,−5.28) 106.80(46.94,213.59) 5.16(2.27,10.32) 25.64(10.64,52.62) 0.96(0.40,1.97) −5.08(−5.95,−4.21)
Typhoid fever Republic of Peru 112.92(65.41,182.37) 1.06(0.61,1.71) 68.85(39.43,110.21) 0.55(0.32,0.88) −2.63(−2.86,−2.41) 82.12(33.47,168.73) 0.77(0.31,1.58) 43.46(16.05,96.72) 0.35(0.13,0.77) −2.56(−2.82,−2.31)
Typhoid fever Republic of Poland 25.29(12.90,47.20) 0.20(0.10,0.38) 21.95(9.26,40.70) 0.29(0.12,0.53) 1.66(0.96,2.37) 1.03(0.86,1.26) 0.01(0.01,0.01) 0.23(0.10,0.47) 0.00(0.00,0.01) −2.77(−4.46,−1.05)
Typhoid fever Republic of Rwanda 18,567.19(13025.72,24786.96) 448.63(314.73,598.91) 8534.07(5702.67,12376.94) 132.56(88.58,192.25) −3.89(−3.94,−3.83) 23,264.86(10591.06,44206.41) 562.13(255.90,1068.13) 13,753.80(6050.54,27159.37) 213.63(93.98,421.85) −2.97(−3.32,−2.62)
Typhoid fever Republic of San Marino 0.01(0.00,0.01) 0.10(0.06,0.17) 0.01(0.00,0.01) 0.09(0.06,0.15) −0.32(−0.71,0.08) 0.01(0.00,0.02) 0.11(0.03,0.33) 0.00(0.00,0.01) 0.05(0.01,0.13) −1.85(−2.32,−1.38)
Typhoid fever Republic of Senegal 27,010.18(18435.16,37506.10) 607.39(414.56,843.41) 11,357.48(7734.40,15969.52) 139.95(95.31,196.78) −4.70(−4.82,−4.57) 42,064.95(19572.89,80369.57) 945.93(440.14,1807.30) 20,325.54(9599.90,38024.32) 250.46(118.29,468.55) −3.75(−4.04,−3.45)
Typhoid fever Republic of Serbia 1.40(0.75,2.26) 0.05(0.03,0.08) 0.77(0.43,1.23) 0.04(0.02,0.07) −0.37(−0.52,−0.23) 1.64(0.62,3.68) 0.06(0.02,0.13) 0.89(0.32,1.95) 0.05(0.02,0.10) −0.15(−0.63,0.33)
Typhoid fever Republic of Seychelles 148.25(102.69,203.30) 474.54(328.71,650.72) 60.66(39.75,87.67) 198.70(130.22,287.17) −2.69(−2.76,−2.62) 88.72(39.16,160.08) 283.97(125.35,512.41) 24.61(11.27,46.32) 80.62(36.93,151.74) −2.75(−3.10,−2.40)
Typhoid fever Republic of Sierra Leone 14,103.27(9411.51,19349.95) 639.40(426.69,877.27) 7482.73(5112.54,10532.75) 164.43(112.35,231.46) −4.41(−4.46,−4.36) 20,251.37(8733.35,40845.59) 918.14(395.94,1851.82) 11,379.94(4949.73,23650.27) 250.07(108.77,519.71) −4.31(−4.60,−4.01)
Typhoid fever Republic of Singapore 0.47(0.27,0.80) 0.05(0.03,0.09) 0.14(0.07,0.25) 0.01(0.01,0.02) −5.07(−5.99,−4.14) 0.05(0.03,0.08) 0.01(0.00,0.01) 0.03(0.02,0.04) 0.00(0.00,0.00) −4.69(−8.84,−0.36)
Typhoid fever Republic of Slovenia 0.16(0.08,0.27) 0.03(0.02,0.05) 0.12(0.06,0.20) 0.03(0.02,0.05) 0.24(0.07,0.40) 0.02(0.02,0.03) 0.00(0.00,0.01) 0.00(0.00,0.01) 0.00(0.00,0.00) −4.41(−4.57,−4.26)
Typhoid fever Republic of South Africa 467.63(315.44,646.71) 2.65(1.79,3.67) 410.23(278.56,560.42) 2.06(1.40,2.81) −0.30(−0.43,−0.17) 414.00(173.45,814.23) 2.35(0.98,4.62) 358.36(147.93,709.10) 1.80(0.74,3.56) −0.26(−0.60,0.09)
Typhoid fever Republic of South Sudan 15,962.74(11323.46,21915.21) 485.77(344.59,666.91) 8155.08(5817.89,11103.58) 148.62(106.02,202.35) −3.81(−3.88,−3.75) 15,240.14(6668.53,29731.09) 463.78(202.93,904.76) 12,851.95(5693.10,25810.49) 234.21(103.75,470.36) −1.93(−2.30,−1.56)
Typhoid fever Republic of Sudan 20,934.02(14895.43,29683.54) 189.51(134.85,268.72) 10,253.88(6304.86,14477.85) 47.97(29.50,67.73) −4.40(−4.46,−4.33) 25,158.90(10991.17,51557.92) 227.76(99.50,466.75) 13,808.01(5594.65,27066.45) 64.60(26.17,126.63) −3.64(−3.86,−3.43)
Typhoid fever Republic of Suriname 4.12(2.47,6.54) 2.41(1.45,3.82) 2.17(1.17,3.61) 1.14(0.61,1.90) −2.43(−2.56,−2.29) 2.73(0.98,5.68) 1.60(0.57,3.32) 1.51(0.57,3.34) 0.80(0.30,1.76) −2.17(−2.44,−1.90)
Typhoid fever Republic of Tajikistan 5.53(2.88,10.47) 0.19(0.10,0.36) 7.81(4.16,14.14) 0.18(0.09,0.32) −0.14(−0.32,0.03) 5.31(2.05,11.00) 0.18(0.07,0.38) 9.13(3.40,19.55) 0.20(0.08,0.44) 0.46(0.28,0.63)
Typhoid fever Republic of the Congo 1352.10(904.23,1845.92) 101.92(68.16,139.14) 916.15(650.52,1287.86) 36.84(26.16,51.79) −3.03(−3.14,−2.91) 1465.51(649.72,2812.62) 110.46(48.97,212.00) 1007.84(439.97,2051.70) 40.53(17.69,82.50) −2.69(−2.94,−2.43)
Typhoid fever Republic of the Gambia 3381.71(2354.99,4539.35) 601.95(419.19,808.01) 1839.08(1257.13,2456.99) 145.20(99.25,193.98) −4.59(−4.63,−4.55) 4148.87(1832.39,7886.83) 738.51(326.17,1403.87) 3029.62(1390.57,5585.99) 239.19(109.79,441.02) −3.76(−4.06,−3.45)
Typhoid fever Republic of the Marshall Islands 98.55(69.92,136.77) 367.99(261.06,510.69) 19.64(13.89,27.04) 85.13(60.20,117.21) −4.67(−4.72,−4.61) 63.60(28.40,114.37) 237.49(106.04,427.04) 18.16(7.20,36.94) 78.72(31.20,160.12) −3.67(−3.93,−3.40)
Typhoid fever Republic of the Niger 32,397.34(21817.81,45535.73) 667.77(449.70,938.57) 28,591.82(19693.75,39500.62) 183.44(126.35,253.42) −4.21(−4.29,−4.13) 42,768.66(18061.22,86537.15) 881.54(372.27,1783.68) 35,472.43(14771.82,72180.56) 227.58(94.77,463.09) −4.22(−4.39,−4.05)
Typhoid fever Republic of the Philippines 76,095.15(53208.14,102536.23) 237.41(166.00,319.90) 92,115.38(64679.43,125013.63) 205.72(144.45,279.19) −0.36(−0.47,−0.25) 83,425.50(37514.02,158130.25) 260.28(117.04,493.35) 101,953.17(47579.83,186669.29) 227.69(106.26,416.88) −0.17(−0.35,0.01)
Typhoid fever Republic of the Union of Myanmar 138,100.27(91861.20,183606.41) 722.61(480.67,960.72) 53,416.28(36475.36,75491.47) 257.20(175.63,363.50) −3.48(−3.59,−3.37) 131,670.45(57070.70,250368.78) 688.97(298.62,1310.06) 72,053.49(33991.88,139390.52) 346.94(163.67,671.17) −2.27(−2.40,−2.15)
Typhoid fever Republic of Trinidad and Tobago 2.50(1.36,4.03) 0.48(0.26,0.78) 1.08(0.60,1.79) 0.30(0.17,0.49) −2.18(−2.48,−1.88) 0.06(0.04,0.08) 0.01(0.01,0.02) 0.02(0.01,0.02) 0.00(0.00,0.01) −3.11(−4.14,−2.07)
Typhoid fever Republic of Tunisia 4830.20(3283.24,6711.87) 121.06(82.29,168.22) 1054.70(727.21,1509.23) 29.42(20.28,42.09) −4.17(−4.38,−3.96) 4659.98(2020.14,9740.17) 116.79(50.63,244.11) 802.38(349.69,1567.73) 22.38(9.75,43.72) −4.77(−4.98,−4.56)
Typhoid fever Republic of Turkey 32,601.91(23172.44,44698.75) 122.19(86.85,167.53) 6627.99(4251.23,9434.28) 26.82(17.20,38.18) −4.82(−4.87,−4.76) 28,733.63(12920.46,57457.33) 107.69(48.42,215.34) 5235.28(2347.32,10258.78) 21.18(9.50,41.51) −5.00(−5.27,−4.72)
Typhoid fever Republic of Uganda 49,393.68(34059.32,64750.91) 479.65(330.74,628.78) 34,130.15(22737.40,48180.97) 136.83(91.16,193.16) −3.99(−4.02,−3.97) 40,336.86(17574.76,79439.94) 391.70(170.67,771.43) 48,648.65(19640.22,98724.12) 195.04(78.74,395.79) −1.78(−2.02,−1.54)
Typhoid fever Republic of Uzbekistan 2.22(0.82,4.32) 0.02(0.01,0.04) 2.04(0.71,4.03) 0.02(0.01,0.03) −0.79(−0.91,−0.67) 4.90(2.09,9.45) 0.05(0.02,0.09) 0.61(0.29,1.21) 0.00(0.00,0.01) −6.67(−6.91,−6.44)
Typhoid fever Republic of Vanuatu 354.67(229.11,518.54) 425.02(274.55,621.39) 178.43(124.48,246.96) 121.02(84.43,167.50) −4.08(−4.15,−4.02) 279.69(117.55,544.44) 335.17(140.87,652.43) 169.91(72.66,322.95) 115.24(49.28,219.04) −3.19(−3.53,−2.85)
Typhoid fever Republic of Yemen 16,429.67(11597.37,23455.80) 195.40(137.93,278.97) 6921.75(4916.15,9525.51) 39.62(28.14,54.52) −5.27(−5.37,−5.16) 13,898.03(6008.72,28954.82) 165.29(71.46,344.37) 7545.93(3503.18,14467.54) 43.19(20.05,82.80) −4.10(−4.35,−3.86)
Typhoid fever Republic of Zambia 21,106.00(15046.49,29973.35) 449.02(320.10,637.66) 12,454.32(8653.15,17065.09) 119.13(82.77,163.24) −4.14(−4.28,−4.01) 25,994.94(11204.65,50808.11) 553.03(238.37,1080.91) 24,484.82(11064.59,46454.93) 234.21(105.84,444.36) −2.06(−2.34,−1.78)
Typhoid fever Republic of Zimbabwe 139.78(93.41,191.07) 2.32(1.55,3.17) 182.54(122.49,248.09) 2.29(1.53,3.11) 0.18(0.09,0.26) 117.37(44.96,237.48) 1.95(0.75,3.94) 243.75(101.05,480.31) 3.05(1.27,6.02) 2.48(1.75,3.21)
Typhoid fever Romania 45.62(27.62,75.17) 0.61(0.37,1.00) 11.28(6.66,19.52) 0.28(0.16,0.48) −1.88(−2.16,−1.60) 0.61(0.40,0.95) 0.01(0.01,0.01) 0.13(0.08,0.22) 0.00(0.00,0.01) −3.80(−5.53,−2.03)
Typhoid fever Russian Federation 179.71(111.22,274.90) 0.40(0.25,0.61) 110.03(70.42,167.91) 0.33(0.21,0.50) −0.21(−0.39,−0.02) 42.30(32.55,59.86) 0.09(0.07,0.13) 5.64(2.33,12.85) 0.02(0.01,0.04) −5.06(−5.57,−4.55)
Typhoid fever Saint Kitts and Nevis 0.30(0.17,0.50) 1.64(0.93,2.71) 0.14(0.07,0.23) 0.97(0.52,1.63) −1.46(−1.63,−1.30) 0.07(0.05,0.09) 0.36(0.27,0.47) 0.04(0.02,0.06) 0.25(0.11,0.43) −1.21(−1.41,−1.01)
Typhoid fever Saint Lucia 1.13(0.67,1.83) 1.70(1.01,2.74) 0.28(0.14,0.52) 0.68(0.33,1.24) −2.43(−2.68,−2.18) 0.04(0.03,0.06) 0.07(0.05,0.09) 0.00(0.00,0.01) 0.01(0.00,0.01) −5.91(−7.10,−4.70)
Typhoid fever Saint Vincent and the Grenadines 0.97(0.57,1.60) 1.80(1.06,2.97) 0.24(0.12,0.41) 0.72(0.37,1.21) −2.45(−2.69,−2.20) 0.02(0.01,0.03) 0.04(0.03,0.05) 0.00(0.00,0.00) 0.01(0.00,0.01) −3.63(−4.17,−3.09)
Typhoid fever Slovak Republic 0.73(0.41,1.16) 0.04(0.02,0.07) 0.51(0.28,0.85) 0.05(0.03,0.08) 0.92(0.70,1.15) 0.55(0.16,1.33) 0.03(0.01,0.08) 0.33(0.09,0.78) 0.03(0.01,0.07) 0.77(0.49,1.05)
Typhoid fever Socialist Republic of Viet Nam 275,182.07(212834.39,348227.98) 817.37(632.18,1034.33) 49,142.72(35564.00,66840.24) 155.42(112.48,211.39) −5.33(−5.40,−5.26) 250,301.63(123868.45,434070.39) 743.47(367.92,1289.31) 59,808.12(27062.83,104954.92) 189.15(85.59,331.94) −4.27(−4.37,−4.16)
Typhoid fever Solomon Islands 834.20(584.30,1160.46) 428.63(300.23,596.28) 418.77(287.74,593.74) 126.61(87.00,179.52) −3.89(−3.95,−3.82) 738.44(320.95,1468.99) 379.43(164.91,754.81) 507.29(228.78,943.59) 153.38(69.17,285.29) −2.86(−3.19,−2.53)
Typhoid fever State of Eritrea 9741.13(6455.49,13410.34) 495.28(328.22,681.84) 4418.36(2948.97,6165.42) 137.36(91.68,191.67) −4.05(−4.10,−3.99) 10,103.76(4374.95,18370.54) 513.72(222.44,934.04) 8244.43(3597.25,16254.82) 256.31(111.83,505.33) −2.32(−2.45,−2.19)
Typhoid fever State of Israel 0.69(0.41,1.10) 0.03(0.02,0.05) 0.86(0.49,1.39) 0.03(0.01,0.04) −0.39(−0.73,−0.05) 0.01(0.01,0.02) 0.00(0.00,0.00) 0.01(0.01,0.02) 0.00(0.00,0.00) −2.28(−3.29,−1.27)
Typhoid fever State of Kuwait 625.61(418.07,869.55) 91.20(60.95,126.76) 254.82(163.44,352.52) 23.26(14.92,32.18) −4.29(−4.36,−4.22) 455.39(136.35,1067.80) 66.39(19.88,155.67) 160.96(47.59,383.43) 14.69(4.34,35.00) −4.49(−4.65,−4.33)
Typhoid fever State of Libya 3710.41(2591.10,5074.54) 160.74(112.25,219.84) 566.17(394.72,776.55) 27.12(18.91,37.20) −5.60(−5.84,−5.36) 2689.22(1167.88,5264.85) 116.50(50.59,228.08) 409.07(175.48,845.31) 19.60(8.41,40.49) −5.48(−5.61,−5.36)
Typhoid fever State of Qatar 171.56(119.33,241.26) 112.07(77.96,157.60) 175.20(117.53,251.55) 29.34(19.68,42.13) −4.14(−4.24,−4.05) 104.17(31.53,264.65) 68.05(20.60,172.88) 85.57(26.37,211.13) 14.33(4.42,35.36) −4.13(−4.46,−3.80)
Typhoid fever Sultanate of Oman 1343.97(909.12,1946.89) 134.09(90.70,194.24) 428.65(294.41,589.47) 28.73(19.74,39.51) −4.53(−4.88,−4.19) 938.23(270.42,2400.80) 93.61(26.98,239.53) 246.78(73.64,578.27) 16.54(4.94,38.76) −4.64(−5.10,−4.18)
Typhoid fever Swiss Confederation 0.34(0.18,0.54) 0.02(0.01,0.03) 0.39(0.21,0.65) 0.02(0.01,0.04) 0.09(0.02,0.16) 0.03(0.03,0.04) 0.00(0.00,0.00) 0.01(0.01,0.02) 0.00(0.00,0.00) −3.41(−4.73,−2.07)
Typhoid fever Syrian Arab Republic 9294.39(6210.07,12850.06) 126.42(84.47,174.78) 1386.76(935.56,2003.43) 25.49(17.20,36.83) −5.03(−5.09,−4.97) 11,005.49(4887.09,21381.16) 149.70(66.47,290.82) 2401.15(1041.99,4522.29) 44.14(19.15,83.13) −3.66(−4.01,−3.31)
Typhoid fever Taiwan (Province of China) 990.22(645.32,1401.22) 13.55(8.83,19.17) 140.64(90.79,203.95) 3.48(2.24,5.04) −4.38(−4.51,−4.24) 727.29(310.44,1409.55) 9.95(4.25,19.29) 107.56(45.73,209.07) 2.66(1.13,5.17) −4.10(−4.20,−3.99)
Typhoid fever Togolese Republic 12,775.07(8602.42,17211.11) 593.44(399.61,799.50) 6297.48(4301.32,8731.57) 150.82(103.02,209.12) −4.39(−4.48,−4.31) 15,672.68(6965.91,29900.74) 728.04(323.59,1388.97) 8097.19(3577.43,15321.91) 193.93(85.68,366.96) −4.15(−4.30,−4.01)
Typhoid fever Tokelau 2.28(1.57,3.17) 300.96(206.63,418.42) 0.36(0.24,0.51) 70.97(47.13,100.60) −4.72(−4.79,−4.65) 2.11(0.87,4.03) 277.61(114.81,531.51) 3.34(1.45,6.38) 653.41(284.01,1247.59) −2.34(−4.27,−0.37)
Typhoid fever Turkmenistan 9.69(5.33,15.40) 0.51(0.28,0.82) 3.30(1.80,5.62) 0.17(0.09,0.29) −3.50(−3.87,−3.12) 363.13(186.54,667.04) 19.26(9.89,35.38) 22.67(8.26,58.89) 1.16(0.42,3.00) −8.96(−9.23,−8.69)
Typhoid fever Tuvalu 15.88(10.62,22.38) 371.55(248.46,523.79) 3.95(2.76,5.67) 80.42(56.26,115.40) −4.85(−4.92,−4.79) 12.42(5.14,24.53) 290.64(120.33,573.99) 3.46(1.53,7.10) 70.44(31.18,144.46) −4.48(−4.64,−4.32)
Typhoid fever Ukraine 11.96(6.26,19.54) 0.08(0.04,0.13) 5.33(2.80,9.18) 0.06(0.03,0.11) 0.31(−0.06,0.68) 12.87(5.33,24.81) 0.09(0.04,0.16) 6.63(2.59,13.06) 0.08(0.03,0.15) 1.37(0.75,2.00)
Typhoid fever Union of the Comoros 1226.29(840.96,1622.36) 463.94(318.16,613.79) 406.70(279.66,541.82) 129.54(89.08,172.58) −4.10(−4.15,−4.06) 1524.75(611.13,3080.47) 576.86(231.21,1165.44) 731.38(337.21,1329.08) 232.96(107.41,423.34) −3.06(−3.40,−2.71)
Typhoid fever United Arab Emirates 759.23(497.71,1104.27) 107.39(70.40,156.19) 466.81(330.61,653.61) 27.54(19.50,38.56) −4.15(−4.30,−4.01) 595.34(173.91,1495.09) 84.20(24.60,211.46) 176.30(55.67,427.75) 10.40(3.28,25.23) −5.70(−6.07,−5.32)
Typhoid fever United Kingdom of Great Britain and Northern Ireland 23.81(9.76,46.91) 0.16(0.07,0.32) 16.93(6.46,35.29) 0.11(0.04,0.23) −0.63(−0.91,−0.34) 0.61(0.46,0.88) 0.00(0.00,0.01) 0.41(0.29,0.58) 0.00(0.00,0.00) 0.12(−0.74,1.00)
Typhoid fever United Mexican States 5766.58(3773.53,8335.16) 13.30(8.70,19.22) 2341.57(1549.92,3368.60) 5.43(3.59,7.81) −3.00(−3.31,−2.68) 15,703.57(13970.06,17743.47) 36.21(32.21,40.91) 488.03(378.68,641.40) 1.13(0.88,1.49) −10.78(−11.85,−9.70)
Typhoid fever United Republic of Tanzania 135,453.21(91901.24,186956.98) 907.67(615.83,1252.79) 69,842.58(51487.98,91017.09) 226.33(166.85,294.95) −4.22(−4.29,−4.14) 181,152.01(81601.55,353317.28) 1213.89(546.81,2367.57) 124,825.51(60797.36,233855.09) 404.51(197.02,757.84) −2.75(−3.00,−2.49)
Typhoid fever United States of America 65.06(34.33,108.93) 0.09(0.05,0.15) 61.57(29.91,107.83) 0.08(0.04,0.13) −0.14(−0.29,0.01) 4.35(3.77,5.03) 0.01(0.01,0.01) 4.11(3.44,4.92) 0.01(0.00,0.01) −0.04(−1.34,1.28)
Typhoid fever United States Virgin Islands 0.54(0.29,0.89) 1.29(0.70,2.12) 0.14(0.08,0.23) 0.77(0.41,1.26) −1.55(−1.66,−1.44) 0.35(0.10,0.91) 0.83(0.24,2.18) 0.06(0.02,0.15) 0.31(0.09,0.83) −1.42(−2.05,−0.79)
Varicella and herpes zoster American Samoa 723.77(667.88,770.08) 3024.96(2791.36,3218.50) 390.91(367.82,410.02) 2043.60(1922.84,2143.47) −1.24(−1.31,−1.18) 5.28(3.19,7.97) 22.05(13.33,33.32) 2.72(1.62,4.33) 14.21(8.49,22.65) −1.45(−1.61,−1.30)
Varicella and herpes zoster Antigua and Barbuda 594.78(568.07,615.51) 2489.65(2377.88,2576.43) 524.81(501.79,541.49) 2246.23(2147.70,2317.61) −0.59(−0.67,−0.50) 0.30(0.17,0.51) 1.27(0.71,2.11) 0.29(0.16,0.50) 1.25(0.69,2.14) −0.31(−0.60,−0.02)
Varicella and herpes zoster Arab Republic of Egypt 850,488.62(811541.22,890042.65) 3045.86(2906.38,3187.52) 1,301,957.36(1249501.40,1357027.54) 2796.88(2684.20,2915.19) 0.34(0.13,0.55) 8972.91(5491.59,14124.34) 32.13(19.67,50.58) 4405.88(2778.91,6586.79) 9.46(5.97,14.15) −2.79(−3.16,−2.42)
Varicella and herpes zoster Argentine Republic 350,827.23(342297.27,362369.64) 2693.12(2627.64,2781.72) 298,314.01(284096.00,314214.66) 2175.65(2071.95,2291.61) −0.26(−0.40,−0.12) 2206.23(1786.47,2680.92) 16.94(13.71,20.58) 1058.43(830.50,1365.14) 7.72(6.06,9.96) −2.33(−2.58,−2.08)
Varicella and herpes zoster Australia 125,480.08(120912.26,130566.07) 2426.11(2337.79,2524.45) 151,880.74(146350.74,157475.61) 2434.65(2346.00,2524.33) 0.10(0.01,0.19) 160.33(131.31,193.19) 3.10(2.54,3.74) 236.46(181.67,303.53) 3.79(2.91,4.87) −0.21(−0.79,0.38)
Varicella and herpes zoster Barbados 1981.61(1899.55,2035.79) 2333.94(2237.29,2397.75) 1370.56(1306.43,1420.82) 2064.70(1968.09,2140.42) −0.53(−0.67,−0.39) 1.23(0.72,1.99) 1.44(0.85,2.34) 2.72(1.67,4.31) 4.10(2.52,6.49) 5.69(4.48,6.91)
Varicella and herpes zoster Belize 2906.88(2770.09,3006.85) 2833.87(2700.51,2931.33) 3818.44(3675.85,3935.68) 2258.77(2174.42,2328.12) −0.72(−0.78,−0.66) 1.97(1.37,2.92) 1.92(1.33,2.85) 2.20(1.26,3.62) 1.30(0.75,2.14) −1.02(−1.95,−0.07)
Varicella and herpes zoster Bermuda 415.76(392.93,432.12) 2614.63(2471.09,2717.52) 251.49(237.61,262.04) 2187.42(2066.65,2279.16) −0.57(−0.64,−0.50) 0.20(0.10,0.35) 1.26(0.65,2.21) 0.15(0.08,0.25) 1.28(0.69,2.13) 0.13(0.07,0.20)
Varicella and herpes zoster Bolivarian Republic of Venezuela 260,006.54(253554.82,265290.78) 2864.75(2793.66,2922.97) 220,913.25(216590.24,224987.02) 2524.21(2474.81,2570.75) −0.01(−0.18,0.15) 2742.71(2353.54,3149.25) 30.22(25.93,34.70) 589.95(406.47,824.28) 6.74(4.64,9.42) −5.96(−6.44,−5.47)
Varicella and herpes zoster Bosnia and Herzegovina 35,418.67(34485.54,36719.51) 2390.32(2327.34,2478.11) 15,218.81(14718.01,15954.93) 2288.27(2212.97,2398.96) −0.01(−0.27,0.24) 142.88(91.13,211.89) 9.64(6.15,14.30) 21.91(13.81,33.31) 3.29(2.08,5.01) −4.17(−4.73,−3.61)
Varicella and herpes zoster Brunei Darussalam 3442.31(3295.23,3585.63) 2992.65(2864.78,3117.24) 3179.50(3062.69,3283.22) 2462.10(2371.65,2542.42) −0.82(−0.97,−0.66) 19.79(12.35,30.04) 17.20(10.73,26.11) 9.37(6.19,13.34) 7.25(4.79,10.33) −2.77(−3.08,−2.46)
Varicella and herpes zoster Burkina Faso 196,876.14(190716.32,202237.94) 3480.09(3371.20,3574.87) 422,636.72(408998.61,433105.31) 3300.35(3193.85,3382.10) −0.16(−0.18,−0.13) 4534.69(2656.62,7018.12) 80.16(46.96,124.06) 7285.50(4022.54,11702.45) 56.89(31.41,91.38) −0.74(−1.03,−0.45)
Varicella and herpes zoster Canada 198,040.66(188490.23,204351.63) 2583.80(2459.20,2666.14) 193,204.09(185280.80,200057.01) 2347.88(2251.59,2431.16) −0.18(−0.33,−0.03) 318.60(249.03,402.11) 4.16(3.25,5.25) 241.07(182.22,325.75) 2.93(2.21,3.96) −1.31(−1.40,−1.22)
Varicella and herpes zoster Central African Republic 54,365.47(52746.80,55886.79) 3631.28(3523.17,3732.90) 87,210.81(85487.03,88886.64) 3013.50(2953.93,3071.40) −0.56(−0.60,−0.51) 1907.56(1080.77,2994.67) 127.41(72.19,200.03) 2977.98(1669.10,4840.26) 102.90(57.67,167.25) −0.63(−0.78,−0.48)
Varicella and herpes zoster Commonwealth of Dominica 865.65(827.61,893.81) 2641.37(2525.30,2727.32) 359.64(342.50,377.07) 1851.37(1763.13,1941.09) −1.19(−1.30,−1.08) 7.79(4.69,11.66) 23.76(14.30,35.59) 2.61(1.59,4.19) 13.43(8.18,21.56) −1.86(−2.03,−1.69)
Varicella and herpes zoster Commonwealth of the Bahamas 2580.98(2477.03,2651.29) 2397.33(2300.77,2462.64) 2169.71(2073.83,2263.92) 1882.34(1799.16,1964.07) −0.89(−1.05,−0.72) 1.56(0.89,2.50) 1.45(0.83,2.32) 3.28(2.05,4.82) 2.84(1.78,4.18) 3.28(2.27,4.30)
Varicella and herpes zoster Cook Islands 216.29(201.18,226.45) 2511.97(2336.52,2629.95) 114.03(106.88,118.79) 2200.09(2062.20,2292.09) −0.53(−0.62,−0.44) 1.16(0.70,1.77) 13.45(8.16,20.57) 0.25(0.16,0.37) 4.83(3.14,7.11) −3.50(−3.65,−3.35)
Varicella and herpes zoster Czech Republic 66,304.21(64872.81,68212.24) 2178.27(2131.25,2240.96) 55,993.98(54034.76,58288.29) 2521.66(2433.43,2624.99) 1.09(0.82,1.37) 58.93(42.99,83.98) 1.94(1.41,2.76) 27.48(17.05,44.37) 1.24(0.77,2.00) 0.11(−0.55,0.78)
Varicella and herpes zoster Democratic People’s Republic of Korea 237,002.68(225998.05,246071.91) 3042.65(2901.37,3159.08) 154,345.61(150210.40,159274.14) 2337.76(2275.13,2412.41) −1.08(−1.20,−0.96) 2074.38(1170.51,3244.79) 26.63(15.03,41.66) 693.49(386.29,1117.52) 10.50(5.85,16.93) −3.28(−3.45,−3.12)
Varicella and herpes zoster Democratic Republic of Sao Tome and Principe 2098.83(2045.90,2151.33) 3003.31(2927.56,3078.42) 2505.62(2449.56,2576.38) 2461.24(2406.17,2530.75) −0.51(−0.71,−0.31) 44.09(25.48,69.75) 63.09(36.46,99.80) 23.44(13.04,36.52) 23.02(12.81,35.87) −2.64(−3.22,−2.06)
Varicella and herpes zoster Democratic Republic of the Congo 770,917.04(746557.05,791692.90) 3560.79(3448.27,3656.75) 1,368,205.83(1341481.06,1401683.88) 2855.96(2800.18,2925.84) −0.60(−0.69,−0.51) 17,162.54(9597.77,27639.39) 79.27(44.33,127.66) 15,846.58(8348.38,26365.64) 33.08(17.43,55.04) −2.23(−2.52,−1.94)
Varicella and herpes zoster Democratic Republic of Timor−Leste 11,768.21(10238.29,13135.95) 2893.84(2517.63,3230.17) 16,330.76(14537.19,17895.89) 2382.56(2120.88,2610.90) −0.79(−0.86,−0.72) 232.68(133.93,359.44) 57.22(32.93,88.39) 184.11(111.43,275.57) 26.86(16.26,40.20) −2.80(−3.11,−2.49)
Varicella and herpes zoster Democratic Socialist Republic of Sri Lanka 142,977.27(120128.91,164060.40) 1974.79(1659.21,2265.99) 127,712.94(106543.15,146784.22) 1850.93(1544.12,2127.33) 0.38(0.17,0.60) 1221.39(814.35,1780.32) 16.87(11.25,24.59) 365.35(226.73,551.48) 5.29(3.29,7.99) −3.83(−4.13,−3.53)
Varicella and herpes zoster Dominican Republic 99,985.37(95659.81,103619.11) 2854.98(2731.46,2958.73) 101,507.07(97084.01,104823.81) 2608.98(2495.29,2694.22) −0.47(−0.63,−0.32) 1272.35(782.06,1966.44) 36.33(22.33,56.15) 555.49(294.77,918.25) 14.28(7.58,23.60) −2.74(−3.20,−2.27)
Varicella and herpes zoster Eastern Republic of Uruguay 28,223.90(27588.16,29080.84) 2620.54(2561.51,2700.11) 19,607.16(18778.61,20547.89) 2170.55(2078.82,2274.69) −0.46(−0.59,−0.34) 201.17(168.55,244.41) 18.68(15.65,22.69) 25.06(18.21,35.46) 2.77(2.02,3.93) −8.20(−10.06,−6.31)
Varicella and herpes zoster Federal Democratic Republic of Ethiopia 1,044,252.73(1012790.11,1071420.14) 3543.78(3437.00,3635.97) 1,631,428.54(1600448.29,1667545.19) 2852.25(2798.08,2915.39) −0.81(−0.86,−0.75) 38,090.41(27071.95,55164.19) 129.26(91.87,187.21) 21,687.69(15389.75,29811.96) 37.92(26.91,52.12) −4.04(−4.20,−3.89)
Varicella and herpes zoster Federal Democratic Republic of Nepal 315,198.57(291160.23,333974.76) 3045.74(2813.46,3227.18) 298,732.87(276362.60,313980.03) 2398.59(2218.97,2521.01) −0.93(−1.04,−0.82) 6413.90(3959.91,9940.00) 61.98(38.26,96.05) 2524.73(1481.57,4079.12) 20.27(11.90,32.75) −3.39(−3.59,−3.20)
Varicella and herpes zoster Federal Republic of Germany 452,171.48(431866.50,469566.20) 2609.12(2491.96,2709.49) 410,308.52(396410.58,426927.28) 2572.96(2485.81,2677.17) 0.10(−0.08,0.27) 663.74(508.86,881.34) 3.83(2.94,5.09) 462.11(328.14,674.49) 2.90(2.06,4.23) −0.86(−1.07,−0.64)
Varicella and herpes zoster Federal Republic of Nigeria 1,721,163.50(1658871.95,1778637.38) 3547.40(3419.02,3665.86) 3,808,218.91(3733448.06,3889055.52) 2980.47(2921.95,3043.74) −0.54(−0.66,−0.42) 32,963.04(25946.96,42841.75) 67.94(53.48,88.30) 54,897.43(33931.07,76095.57) 42.97(26.56,59.56) −1.22(−1.38,−1.06)
Varicella and herpes zoster Federal Republic of Somalia 164,581.75(159481.60,169266.83) 3477.81(3370.04,3576.81) 429,900.24(418049.74,440410.24) 3362.69(3270.00,3444.90) 0.02(−0.12,0.16) 4487.71(2438.03,7654.81) 94.83(51.52,161.76) 11,048.02(5785.03,18395.04) 86.42(45.25,143.89) 0.02(−0.36,0.40)
Varicella and herpes zoster Federated States of Micronesia 1551.93(1474.43,1616.19) 2699.11(2564.32,2810.87) 962.34(923.29,993.63) 2322.02(2227.78,2397.50) −0.46(−0.51,−0.41) 28.49(17.20,43.76) 49.54(29.91,76.11) 8.98(5.22,14.29) 21.67(12.59,34.49) −2.57(−2.65,−2.50)
Varicella and herpes zoster Federative Republic of Brazil 1,625,343.47(1594674.73,1665377.97) 2418.93(2373.29,2478.51) 1,655,941.05(1630130.04,1685081.47) 2590.77(2550.39,2636.36) 0.33(0.27,0.39) 17,127.03(14447.19,20796.94) 25.49(21.50,30.95) 7755.90(6025.57,9602.82) 12.13(9.43,15.02) −1.78(−2.72,−0.84)
Varicella and herpes zoster French Republic 402,216.22(389848.23,415250.21) 2491.75(2415.13,2572.50) 369,326.91(358684.58,382136.25) 2344.69(2277.12,2426.01) −0.12(−0.23,−0.01) 1006.67(838.97,1210.37) 6.24(5.20,7.50) 529.65(379.44,739.39) 3.36(2.41,4.69) −2.28(−2.47,−2.09)
Varicella and herpes zoster Gabonese Republic 16,077.42(15646.76,16479.65) 3163.72(3078.97,3242.87) 21,425.39(20920.28,22046.10) 2590.58(2529.51,2665.63) −0.57(−0.64,−0.49) 275.70(162.79,427.02) 54.25(32.03,84.03) 165.99(87.39,290.69) 20.07(10.57,35.15) −2.73(−3.10,−2.36)
Varicella and herpes zoster Georgia 45,946.36(44436.71,48211.18) 2557.10(2473.08,2683.14) 24,035.83(23247.36,25119.69) 2586.45(2501.61,2703.09) 0.91(0.49,1.33) 17.07(9.06,29.18) 0.95(0.50,1.62) 32.07(21.80,48.69) 3.45(2.35,5.24) 5.67(4.44,6.91)
Varicella and herpes zoster Grand Duchy of Luxembourg 2393.36(2322.73,2456.20) 2712.56(2632.52,2783.78) 3407.22(3313.62,3508.66) 2525.38(2456.01,2600.57) −0.50(−0.62,−0.39) 1.72(0.99,2.73) 1.95(1.12,3.10) 2.56(1.53,4.30) 1.90(1.14,3.18) 0.14(−0.32,0.60)
Varicella and herpes zoster Greenland 555.22(531.42,575.09) 3103.23(2970.17,3214.24) 402.00(387.37,418.64) 2615.35(2520.18,2723.67) −0.60(−0.89,−0.31) 3.67(2.26,5.67) 20.53(12.62,31.70) 1.13(0.69,1.69) 7.35(4.47,10.96) −3.53(−3.80,−3.26)
Varicella and herpes zoster Grenada 1171.86(1123.33,1211.55) 2779.62(2664.49,2873.75) 683.43(656.63,705.62) 2270.17(2181.16,2343.91) −0.57(−0.60,−0.53) 1.18(0.80,1.66) 2.80(1.90,3.93) 0.48(0.31,0.73) 1.59(1.03,2.41) −1.68(−1.90,−1.46)
Varicella and herpes zoster Guam 1528.40(1407.25,1623.17) 2822.81(2599.06,2997.84) 1238.09(1156.51,1295.48) 2553.55(2385.28,2671.90) −0.55(−0.71,−0.40) 5.99(3.90,9.27) 11.07(7.21,17.12) 4.47(2.76,6.81) 9.23(5.70,14.05) −0.62(−1.16,−0.08)
Varicella and herpes zoster Hashemite Kingdom of Jordan 59,684.20(56689.59,62332.71) 2846.67(2703.84,2972.99) 112,435.34(109021.97,115968.40) 2282.91(2213.60,2354.65) −0.61(−0.78,−0.45) 372.28(232.54,546.08) 17.76(11.09,26.05) 218.88(138.91,319.60) 4.44(2.82,6.49) −5.01(−5.28,−4.74)
Varicella and herpes zoster Hellenic Republic 57,628.87(55445.24,60113.76) 2050.44(1972.75,2138.85) 43,044.43(41498.03,44548.27) 2259.20(2178.03,2338.13) 0.53(0.36,0.70) 40.67(22.23,67.53) 1.45(0.79,2.40) 31.58(18.69,52.68) 1.66(0.98,2.76) 0.29(−0.02,0.61)
Varicella and herpes zoster Hungary 63,408.68(62137.79,65252.63) 2184.83(2141.04,2248.37) 45,648.82(44280.82,47370.46) 2434.11(2361.17,2525.91) 0.50(0.42,0.58) 190.41(157.90,232.33) 6.56(5.44,8.01) 25.34(16.55,38.95) 1.35(0.88,2.08) −5.65(−6.25,−5.04)
Varicella and herpes zoster Independent State of Papua New Guinea 63,580.72(59860.04,66396.85) 2986.91(2812.12,3119.21) 149,700.94(141074.65,156553.01) 3055.71(2879.63,3195.58) 0.07(0.02,0.13) 993.61(569.17,1642.48) 46.68(26.74,77.16) 2151.32(1276.37,3365.61) 43.91(26.05,68.70) 0.06(−0.17,0.29)
Varicella and herpes zoster Independent State of Samoa 2487.25(2336.09,2593.30) 2715.51(2550.47,2831.28) 2839.02(2651.94,2978.63) 2812.53(2627.19,2950.83) 0.10(0.07,0.12) 25.38(14.36,40.07) 27.71(15.68,43.75) 17.56(9.12,28.23) 17.39(9.03,27.97) −1.40(−1.54,−1.27)
Varicella and herpes zoster Ireland 29,674.86(28623.35,30823.20) 2233.18(2154.05,2319.60) 30,637.74(29588.99,31764.76) 2318.24(2238.88,2403.51) 0.57(0.26,0.88) 30.02(19.19,46.33) 2.26(1.44,3.49) 22.54(12.62,39.11) 1.71(0.95,2.96) −0.38(−0.57,−0.19)
Varicella and herpes zoster Islamic Republic of Afghanistan 179,830.15(172055.52,186730.20) 3226.83(3087.33,3350.65) 556,719.05(537777.98,578619.44) 3131.73(3025.18,3254.93) −0.68(−0.92,−0.44) 8346.18(4620.91,13324.77) 149.76(82.92,239.10) 11,992.09(7015.79,18595.58) 67.46(39.47,104.61) −2.34(−2.57,−2.10)
Varicella and herpes zoster Islamic Republic of Iran 861,501.35(825143.68,910553.01) 2734.10(2618.71,2889.77) 616,983.67(588096.45,649880.59) 2386.36(2274.63,2513.60) 0.67(0.22,1.13) 6410.96(5242.63,8341.80) 20.35(16.64,26.47) 1256.65(935.88,1567.14) 4.86(3.62,6.06) −3.27(−3.71,−2.84)
Varicella and herpes zoster Islamic Republic of Mauritania 38,432.21(37279.46,39447.74) 3389.32(3287.66,3478.88) 65,685.92(63924.28,67538.93) 2816.51(2740.98,2895.97) −0.44(−0.53,−0.35) 832.46(483.33,1313.71) 73.41(42.62,115.86) 576.35(341.18,941.90) 24.71(14.63,40.39) −3.27(−3.58,−2.96)
Varicella and herpes zoster Islamic Republic of Pakistan 1,754,659.93(1623081.96,1846586.85) 2878.22(2662.39,3029.01) 2,840,301.93(2626541.73,2976766.54) 2600.44(2404.74,2725.38) −0.15(−0.21,−0.10) 33,331.34(22846.59,46341.13) 54.67(37.48,76.01) 45,939.82(32102.87,64950.92) 42.06(29.39,59.47) −0.46(−0.63,−0.29)
Varicella and herpes zoster Jamaica 27,518.66(26154.53,28415.33) 2518.85(2393.99,2600.92) 17,183.07(16405.55,17788.56) 2107.40(2012.05,2181.66) −0.76(−0.87,−0.66) 24.83(16.22,35.44) 2.27(1.48,3.24) 10.39(5.82,17.37) 1.27(0.71,2.13) −2.21(−2.59,−1.83)
Varicella and herpes zoster Japan 690,074.84(664904.37,715510.22) 2068.35(1992.90,2144.58) 470,800.45(453528.41,488183.67) 2217.28(2135.94,2299.15) 0.24(0.09,0.39) 1370.13(1135.09,1733.94) 4.11(3.40,5.20) 522.50(372.34,734.78) 2.46(1.75,3.46) −1.86(−2.17,−1.56)
Varicella and herpes zoster Kingdom of Bahrain 6073.11(5750.38,6361.37) 3035.10(2873.81,3179.16) 9506.20(9187.72,9889.52) 2355.84(2276.91,2450.83) −0.56(−0.69,−0.44) 34.82(21.61,54.17) 17.40(10.80,27.07) 15.98(10.41,22.61) 3.96(2.58,5.60) −4.77(−4.97,−4.56)
Varicella and herpes zoster Kingdom of Belgium 62,208.08(60624.11,63797.27) 2516.80(2452.71,2581.09) 60,930.93(59211.06,63228.66) 2394.85(2327.25,2485.16) −0.03(−0.13,0.06) 199.67(166.53,244.03) 8.08(6.74,9.87) 137.84(106.52,182.69) 5.42(4.19,7.18) −0.64(−1.07,−0.21)
Varicella and herpes zoster Kingdom of Bhutan 9300.13(8682.84,9746.20) 2730.40(2549.17,2861.36) 5909.22(5460.35,6203.75) 2317.56(2141.52,2433.08) −0.48(−0.57,−0.40) 131.24(58.35,216.39) 38.53(17.13,63.53) 58.88(31.54,99.74) 23.09(12.37,39.12) −2.09(−2.56,−1.62)
Varicella and herpes zoster Kingdom of Cambodia 158,340.67(139275.77,175280.03) 2781.12(2446.26,3078.64) 153,975.47(135426.33,170151.34) 2322.02(2042.29,2565.96) −0.49(−0.66,−0.32) 3850.85(2314.31,5982.16) 67.64(40.65,105.07) 1531.59(903.73,2298.25) 23.10(13.63,34.66) −3.44(−3.56,−3.32)
Varicella and herpes zoster Kingdom of Denmark 30,431.03(29507.57,31256.45) 2433.94(2360.08,2499.96) 31,998.67(31073.24,33026.21) 2472.45(2400.95,2551.85) −0.45(−0.61,−0.29) 57.27(41.68,78.65) 4.58(3.33,6.29) 36.82(25.30,52.63) 2.85(1.95,4.07) −1.22(−1.76,−0.68)
Varicella and herpes zoster Kingdom of Eswatini 14,797.45(14430.97,15179.37) 3101.37(3024.56,3181.41) 14,180.80(13893.74,14534.60) 2650.59(2596.93,2716.71) −0.33(−0.40,−0.27) 205.52(124.97,307.96) 43.08(26.19,64.54) 205.95(123.34,319.89) 38.49(23.05,59.79) 0.06(−0.24,0.35)
Varicella and herpes zoster Kingdom of Lesotho 25,003.52(24392.76,25593.67) 2986.13(2913.19,3056.61) 20,652.70(20276.35,21224.25) 2462.10(2417.24,2530.24) −0.54(−0.57,−0.51) 326.09(196.55,498.27) 38.94(23.47,59.51) 341.56(203.30,536.95) 40.72(24.24,64.01) 0.77(0.48,1.07)
Varicella and herpes zoster Kingdom of Morocco 358,423.98(344396.90,372967.60) 2872.02(2759.63,2988.56) 328,182.91(317031.11,340383.95) 2540.98(2454.63,2635.44) −0.18(−0.26,−0.10) 4558.93(2770.05,6706.75) 36.53(22.20,53.74) 1572.23(862.41,2600.91) 12.17(6.68,20.14) −3.12(−3.39,−2.84)
Varicella and herpes zoster Kingdom of Norway 28,810.93(28053.18,29479.90) 2589.64(2521.53,2649.77) 28,960.24(28234.54,29825.28) 2332.77(2274.31,2402.45) −0.46(−0.55,−0.37) 32.09(24.03,43.74) 2.88(2.16,3.93) 32.00(22.82,45.94) 2.58(1.84,3.70) 0.04(−0.19,0.26)
Varicella and herpes zoster Kingdom of Saudi Arabia 239,251.41(233942.62,246433.22) 2913.65(2849.00,3001.11) 246,099.54(236968.40,256048.81) 2428.60(2338.49,2526.79) −0.51(−0.63,−0.39) 2041.97(1182.08,3312.93) 24.87(14.40,40.35) 433.63(281.73,622.51) 4.28(2.78,6.14) −5.72(−5.85,−5.59)
Varicella and herpes zoster Kingdom of Spain 218,771.85(212423.61,225902.47) 1962.60(1905.65,2026.57) 190,436.97(182351.10,199214.80) 2162.25(2070.44,2261.91) 0.78(0.33,1.22) 355.46(257.76,505.68) 3.19(2.31,4.54) 211.46(140.91,323.81) 2.40(1.60,3.68) −0.67(−1.29,−0.04)
Varicella and herpes zoster Kingdom of Sweden 57,883.55(56097.57,59404.30) 2747.17(2662.41,2819.34) 58,798.96(57374.89,60768.95) 2434.42(2375.46,2515.99) −0.04(−0.32,0.25) 108.81(90.94,130.16) 5.16(4.32,6.18) 100.04(78.28,127.98) 4.14(3.24,5.30) −0.63(−0.97,−0.30)
Varicella and herpes zoster Kingdom of Thailand 486,333.01(433719.75,530512.54) 2138.02(1906.72,2332.25) 273,110.85(242524.05,297424.15) 2001.08(1776.97,2179.22) −0.46(−0.56,−0.36) 3236.31(2065.30,4869.99) 14.23(9.08,21.41) 660.90(450.21,953.78) 4.84(3.30,6.99) −3.82(−4.07,−3.56)
Varicella and herpes zoster Kingdom of the Netherlands 96,875.67(93873.51,99729.74) 2527.37(2449.04,2601.82) 89,168.05(86690.92,91465.19) 2415.78(2348.67,2478.02) −0.45(−0.53,−0.38) 196.52(163.55,246.01) 5.13(4.27,6.42) 178.95(139.18,236.60) 4.85(3.77,6.41) −0.83(−1.22,−0.44)
Varicella and herpes zoster Kingdom of Tonga 1473.40(1369.70,1546.18) 2761.13(2566.80,2897.52) 1389.01(1296.48,1454.17) 2801.40(2614.80,2932.83) 0.10(0.08,0.12) 10.79(6.72,16.06) 20.23(12.60,30.10) 8.18(4.93,12.61) 16.49(9.93,25.43) −0.52(−0.74,−0.30)
Varicella and herpes zoster Kyrgyz Republic 63,692.49(61758.75,66166.29) 3016.62(2925.03,3133.78) 78,888.97(76642.36,82126.44) 2794.68(2715.09,2909.37) 0.44(0.06,0.82) 21.64(12.04,37.80) 1.02(0.57,1.79) 34.28(21.24,53.31) 1.21(0.75,1.89) 1.78(0.96,2.61)
Varicella and herpes zoster Lao People’s Democratic Republic 64,011.63(57193.66,69224.04) 2821.78(2521.23,3051.56) 72,352.69(63716.46,79711.61) 2418.59(2129.90,2664.59) −0.63(−0.75,−0.52) 1726.26(1027.87,2818.69) 76.10(45.31,124.25) 883.89(519.35,1379.73) 29.55(17.36,46.12) −3.15(−3.28,−3.02)
Varicella and herpes zoster Lebanese Republic 38,507.12(36622.23,40342.93) 2875.52(2734.77,3012.61) 41,214.45(39793.87,42765.59) 2473.51(2388.25,2566.60) −0.19(−0.31,−0.08) 166.74(98.78,255.40) 12.45(7.38,19.07) 45.15(29.55,67.75) 2.71(1.77,4.07) −5.01(−5.14,−4.88)
Varicella and herpes zoster Malaysia 196,754.53(169358.89,221710.66) 2358.33(2029.96,2657.45) 215,339.07(186707.42,240989.35) 2099.80(1820.61,2349.92) −0.44(−0.53,−0.35) 1626.54(1013.83,2443.33) 19.50(12.15,29.29) 696.93(448.01,1054.14) 6.80(4.37,10.28) −3.50(−3.82,−3.17)
Varicella and herpes zoster Mongolia 34,236.56(33417.78,35386.84) 3016.11(2943.98,3117.45) 38,774.70(37642.22,40249.77) 2953.82(2867.54,3066.18) 0.86(0.39,1.34) 584.71(364.10,913.52) 51.51(32.08,80.48) 190.97(116.78,285.75) 14.55(8.90,21.77) −3.79(−4.05,−3.54)
Varicella and herpes zoster Montenegro 5249.03(5064.75,5477.68) 2446.89(2360.99,2553.48) 3639.52(3535.26,3775.28) 2420.06(2350.73,2510.33) 0.06(−0.01,0.13) 13.44(8.64,19.96) 6.26(4.03,9.30) 4.19(2.69,6.33) 2.78(1.79,4.21) −2.79(−3.07,−2.51)
Varicella and herpes zoster New Zealand 28,253.82(27484.05,29083.15) 2565.99(2496.08,2641.31) 31,565.49(30822.77,32627.12) 2421.64(2364.66,2503.08) −0.23(−0.31,−0.16) 43.53(36.20,52.36) 3.95(3.29,4.75) 33.12(25.16,43.64) 2.54(1.93,3.35) −0.41(−1.09,0.26)
Varicella and herpes zoster North Macedonia 17,197.36(16769.66,17799.44) 2467.57(2406.20,2553.96) 10,188.74(9899.48,10640.74) 2281.62(2216.84,2382.84) −0.09(−0.30,0.11) 100.05(60.12,144.39) 14.36(8.63,20.72) 14.20(9.47,20.52) 3.18(2.12,4.60) −4.83(−5.19,−4.47)
Varicella and herpes zoster Northern Mariana Islands 456.31(420.57,486.07) 2813.89(2593.49,2997.41) 327.05(307.26,341.76) 2180.80(2048.83,2278.91) −1.46(−1.79,−1.12) 1.79(1.09,2.79) 11.03(6.72,17.22) 0.76(0.51,1.13) 5.08(3.41,7.51) −2.48(−2.74,−2.23)
Varicella and herpes zoster Palestine 38,265.47(36126.56,40195.11) 3205.95(3026.75,3367.62) 61,802.02(59592.38,64232.52) 2566.70(2474.93,2667.64) −0.69(−0.73,−0.65) 243.91(147.77,370.26) 20.43(12.38,31.02) 163.02(102.42,242.44) 6.77(4.25,10.07) −3.19(−3.45,−2.92)
Varicella and herpes zoster People’s Democratic Republic of Algeria 374,184.81(359749.30,388891.50) 2768.34(2661.54,2877.14) 466,421.29(446478.29,487597.51) 2835.59(2714.35,2964.33) 0.74(0.40,1.08) 3325.46(1974.90,5200.50) 24.60(14.61,38.47) 1223.41(748.45,1804.23) 7.44(4.55,10.97) −3.11(−3.36,−2.86)
Varicella and herpes zoster People’s Republic of Bangladesh 1,786,338.51(1648971.98,1888092.48) 2959.51(2731.93,3128.09) 1,396,936.57(1286762.37,1468716.89) 2290.47(2109.82,2408.16) −0.59(−0.66,−0.51) 41,370.84(24827.93,62707.14) 68.54(41.13,103.89) 10,375.60(6293.99,15994.11) 17.01(10.32,26.22) −4.36(−4.47,−4.25)
Varicella and herpes zoster People’s Republic of China 11,282,778.73(11026829.43,11610612.52) 2535.22(2477.71,2608.88) 7,433,981.72(6890636.49,8047679.24) 2223.72(2061.19,2407.30) 0.30(−0.09,0.70) 116,091.70(98672.84,137254.32) 26.09(22.17,30.84) 11,809.06(9255.48,14952.93) 3.53(2.77,4.47) −6.47(−6.72,−6.22)
Varicella and herpes zoster Plurinational State of Bolivia 102,195.71(98738.89,105158.17) 3051.66(2948.43,3140.12) 119,552.93(115965.49,123085.21) 2629.39(2550.49,2707.08) −0.35(−0.46,−0.23) 2914.99(1741.03,4632.14) 87.04(51.99,138.32) 1150.73(684.46,1790.66) 25.31(15.05,39.38) −3.93(−4.06,−3.79)
Varicella and herpes zoster Portuguese Republic 61,325.84(59443.07,63136.94) 2057.25(1994.09,2118.01) 43,692.70(42394.58,45171.10) 2279.52(2211.80,2356.65) 0.21(0.01,0.41) 147.23(115.42,186.29) 4.94(3.87,6.25) 64.69(47.26,89.88) 3.37(2.47,4.69) −1.71(−3.10,−0.30)
Varicella and herpes zoster Principality of Andorra 284.88(276.71,293.32) 2116.67(2055.95,2179.40) 268.17(256.09,280.08) 1865.13(1781.14,1947.95) −0.74(−1.02,−0.46) 0.52(0.33,0.77) 3.86(2.45,5.70) 0.32(0.19,0.50) 2.22(1.35,3.51) −1.80(−1.95,−1.65)
Varicella and herpes zoster Principality of Monaco 124.41(120.65,127.60) 2568.01(2490.39,2633.91) 165.74(160.47,171.49) 2448.26(2370.32,2533.09) −0.30(−0.38,−0.22) 0.18(0.11,0.26) 3.64(2.37,5.29) 0.17(0.11,0.25) 2.45(1.62,3.70) −1.37(−1.47,−1.27)
Varicella and herpes zoster Puerto Rico 31,715.29(30139.63,32759.48) 2380.87(2262.59,2459.26) 11,064.72(10356.34,11790.68) 1693.19(1584.79,1804.28) −1.05(−1.18,−0.91) 59.84(44.86,76.56) 4.49(3.37,5.75) 12.69(8.56,19.07) 1.94(1.31,2.92) −3.16(−4.18,−2.13)
Varicella and herpes zoster Republic of Albania 40,140.14(38845.83,41863.76) 2776.11(2686.59,2895.32) 14,398.39(14000.01,14953.63) 2333.15(2268.60,2423.13) −0.76(−1.10,−0.42) 195.12(121.20,280.15) 13.49(8.38,19.38) 22.69(15.08,33.51) 3.68(2.44,5.43) −4.78(−5.39,−4.17)
Varicella and herpes zoster Republic of Angola 210,728.46(203004.32,217678.28) 3654.66(3520.70,3775.19) 568,328.31(554839.62,584243.89) 3043.14(2970.91,3128.36) −0.48(−0.59,−0.36) 5804.30(3367.71,9381.32) 100.66(58.41,162.70) 8100.53(4497.84,13451.94) 43.37(24.08,72.03) −2.42(−2.76,−2.08)
Varicella and herpes zoster Republic of Armenia 37,767.41(36515.39,39344.04) 2844.32(2750.03,2963.06) 18,579.52(18023.84,19346.63) 2434.68(2361.86,2535.20) 0.41(−0.11,0.94) 11.80(5.83,20.61) 0.89(0.44,1.55) 6.70(3.33,11.59) 0.88(0.44,1.52) 0.15(0.02,0.28)
Varicella and herpes zoster Republic of Austria 46,199.14(44829.10,47553.26) 2466.33(2393.19,2538.62) 43,958.18(42482.38,45519.04) 2504.89(2420.80,2593.84) 0.01(−0.18,0.19) 35.08(20.65,56.16) 1.87(1.10,3.00) 35.26(21.82,55.15) 2.01(1.24,3.14) 1.07(0.76,1.39)
Varicella and herpes zoster Republic of Azerbaijan 89,502.21(87109.66,92927.43) 2859.40(2782.97,2968.83) 72,049.72(69637.94,75086.45) 2364.77(2285.62,2464.44) 0.07(−0.39,0.52) 670.27(412.04,991.68) 21.41(13.16,31.68) 252.51(150.43,393.63) 8.29(4.94,12.92) −2.61(−2.76,−2.45)
Varicella and herpes zoster Republic of Belarus 78,878.90(75956.50,82860.81) 2513.66(2420.53,2640.55) 46,920.62(45051.20,49076.69) 2316.76(2224.46,2423.22) 0.98(0.46,1.50) 77.29(42.43,134.18) 2.46(1.35,4.28) 33.80(22.95,48.89) 1.67(1.13,2.41) −0.50(−0.82,−0.19)
Varicella and herpes zoster Republic of Benin 102,643.02(99590.72,105222.21) 3576.79(3470.42,3666.66) 238,453.39(231867.06,245104.18) 3172.48(3084.86,3260.97) −0.33(−0.36,−0.30) 2739.81(1631.97,4388.89) 95.47(56.87,152.94) 3873.41(1998.61,6866.78) 51.53(26.59,91.36) −1.86(−2.01,−1.72)
Varicella and herpes zoster Republic of Botswana 21,676.95(21180.79,22223.02) 2927.45(2860.44,3001.19) 23,761.49(23254.76,24358.72) 2591.20(2535.94,2656.33) −0.26(−0.35,−0.18) 300.24(182.58,454.80) 40.55(24.66,61.42) 259.87(146.58,427.03) 28.34(15.98,46.57) −1.00(−1.33,−0.66)
Varicella and herpes zoster Republic of Bulgaria 54,129.61(52739.05,56093.57) 2290.44(2231.60,2373.54) 30,627.90(29858.93,31869.63) 2366.39(2306.98,2462.33) 0.88(0.57,1.19) 44.75(31.19,61.60) 1.89(1.32,2.61) 22.58(15.14,32.82) 1.74(1.17,2.54) 0.08(−0.45,0.60)
Varicella and herpes zoster Republic of Burundi 112,921.57(109442.97,115967.75) 3578.98(3468.73,3675.53) 219,421.16(214553.68,224272.72) 3016.29(2949.38,3082.98) −0.26(−0.38,−0.13) 3057.75(1682.97,4677.73) 96.91(53.34,148.26) 3498.36(1746.30,5843.30) 48.09(24.01,80.33) −1.54(−1.92,−1.15)
Varicella and herpes zoster Republic of Cabo Verde 5929.46(5756.30,6108.77) 3049.01(2959.97,3141.22) 4435.58(4319.69,4575.62) 2301.26(2241.14,2373.92) −0.72(−0.86,−0.57) 59.06(32.76,93.74) 30.37(16.85,48.20) 25.01(14.41,38.75) 12.98(7.48,20.10) −3.00(−3.27,−2.72)
Varicella and herpes zoster Republic of Cameroon 207,921.93(200682.37,213690.31) 3502.10(3380.16,3599.26) 490,863.08(480236.16,503218.48) 2904.04(2841.17,2977.13) −0.38(−0.47,−0.28) 4437.73(2469.94,7588.27) 74.75(41.60,127.81) 6730.47(3599.08,11240.19) 39.82(21.29,66.50) −1.30(−1.62,−0.99)
Varicella and herpes zoster Republic of Chad 132,923.97(127507.68,137410.40) 3770.59(3616.95,3897.85) 377,940.04(366732.47,387961.40) 3451.64(3349.29,3543.17) −0.32(−0.36,−0.28) 2790.44(1564.09,4445.66) 79.15(44.37,126.11) 7107.62(4100.98,11730.23) 64.91(37.45,107.13) −0.45(−0.66,−0.24)
Varicella and herpes zoster Republic of Chile 150,075.03(147098.67,153566.07) 2845.27(2788.84,2911.45) 110,489.69(106549.05,115184.92) 2257.78(2177.25,2353.72) −0.46(−0.70,−0.21) 577.29(486.42,695.97) 10.94(9.22,13.19) 241.12(182.39,311.62) 4.93(3.73,6.37) −2.36(−2.76,−1.96)
Varicella and herpes zoster Republic of Colombia 431,803.40(420787.14,440885.10) 2868.59(2795.40,2928.92) 342,318.12(335432.26,348632.48) 2351.18(2303.89,2394.55) −0.83(−0.95,−0.70) 2168.27(1807.40,2526.71) 14.40(12.01,16.79) 839.65(625.73,1143.04) 5.77(4.30,7.85) −3.68(−4.17,−3.19)
Varicella and herpes zoster Republic of Costa Rica 40,011.12(38823.06,40833.65) 2821.36(2737.58,2879.36) 29,517.01(28597.44,30646.63) 2156.14(2088.97,2238.65) −0.44(−0.64,−0.24) 98.97(81.95,119.65) 6.98(5.78,8.44) 33.40(24.40,46.11) 2.44(1.78,3.37) −4.80(−5.58,−4.01)
Varicella and herpes zoster Republic of Croatia 30,509.61(29648.54,31663.53) 2300.12(2235.20,2387.11) 18,498.79(18017.96,19189.08) 2295.90(2236.23,2381.58) 0.19(0.11,0.28) 13.70(8.09,22.54) 1.03(0.61,1.70) 6.98(3.27,12.73) 0.87(0.41,1.58) −0.70(−1.05,−0.34)
Varicella and herpes zoster Republic of Cuba 87,191.43(82666.05,90471.00) 2387.48(2263.57,2477.29) 53,328.07(50575.66,55768.37) 2220.90(2106.27,2322.53) −0.16(−0.30,−0.01) 339.71(267.87,426.97) 9.30(7.33,11.69) 151.11(120.44,187.17) 6.29(5.02,7.79) −1.39(−1.90,−0.88)
Varicella and herpes zoster Republic of Cyprus 6701.29(6541.80,6854.47) 2586.75(2525.19,2645.88) 7645.54(7398.63,7893.27) 2681.82(2595.22,2768.72) 0.40(0.10,0.69) 16.52(10.97,24.52) 6.38(4.24,9.47) 6.90(4.39,10.60) 2.42(1.54,3.72) −3.23(−3.58,−2.89)
Varicella and herpes zoster Republic of C么te d’Ivoire 239,123.88(231591.57,245380.03) 3456.30(3347.42,3546.72) 439,757.43(428294.61,450108.14) 3057.13(2977.44,3129.09) −0.17(−0.24,−0.09) 4597.31(2488.72,7268.05) 66.45(35.97,105.05) 5266.62(2828.42,8807.17) 36.61(19.66,61.23) −1.52(−1.83,−1.20)
Varicella and herpes zoster Republic of Djibouti 6741.50(6524.72,6935.21) 3005.93(2909.27,3092.30) 14,657.71(14338.18,15036.23) 2774.13(2713.65,2845.77) −0.07(−0.18,0.04) 146.37(82.69,229.92) 65.26(36.87,102.52) 245.97(131.58,438.12) 46.55(24.90,82.92) −0.77(−1.34,−0.20)
Varicella and herpes zoster Republic of Ecuador 135,875.48(130631.08,139792.00) 2740.79(2635.01,2819.80) 164,757.40(159057.22,170441.10) 2490.19(2404.03,2576.09) −0.36(−0.42,−0.31) 608.70(513.85,739.63) 12.28(10.36,14.92) 338.87(243.00,452.81) 5.12(3.67,6.84) −2.86(−3.32,−2.39)
Varicella and herpes zoster Republic of El Salvador 80,420.70(78220.99,82457.68) 2918.66(2838.83,2992.59) 59,224.97(58103.05,60533.02) 2486.27(2439.17,2541.19) −0.74(−0.97,−0.50) 964.93(592.37,1467.80) 35.02(21.50,53.27) 203.23(116.65,310.05) 8.53(4.90,13.02) −4.52(−5.10,−3.94)
Varicella and herpes zoster Republic of Equatorial Guinea 8825.33(8534.21,9062.30) 3677.52(3556.21,3776.27) 18,830.62(18408.72,19420.73) 2445.12(2390.34,2521.75) −1.21(−1.27,−1.16) 238.93(139.23,385.64) 99.56(58.02,160.70) 119.71(52.10,224.36) 15.54(6.76,29.13) −6.49(−6.76,−6.22)
Varicella and herpes zoster Republic of Estonia 11,829.27(11447.85,12411.08) 2575.37(2492.33,2702.04) 6869.95(6652.55,7156.01) 2450.91(2373.35,2552.96) 0.82(0.38,1.26) 4.45(2.45,7.65) 0.97(0.53,1.66) 2.50(1.26,4.46) 0.89(0.45,1.59) −0.15(−0.23,−0.07)
Varicella and herpes zoster Republic of Fiji 9295.90(8755.64,9666.06) 2591.51(2440.90,2694.71) 9028.69(8524.74,9381.25) 2575.00(2431.27,2675.55) 0.27(0.16,0.38) 97.38(60.11,153.08) 27.15(16.76,42.67) 85.68(50.40,137.34) 24.44(14.38,39.17) 0.03(−0.19,0.24)
Varicella and herpes zoster Republic of Finland 32,507.73(31754.74,33213.08) 2562.14(2502.79,2617.74) 25,491.81(24741.92,26314.65) 2219.54(2154.25,2291.18) −0.31(−0.44,−0.18) 66.94(52.32,86.93) 5.28(4.12,6.85) 23.84(14.90,36.20) 2.08(1.30,3.15) −3.86(−4.53,−3.19)
Varicella and herpes zoster Republic of Ghana 270,191.62(261909.67,277118.77) 3271.24(3170.97,3355.11) 465,570.62(454343.02,477307.40) 2853.81(2784.98,2925.75) −0.31(−0.36,−0.25) 4158.81(2290.95,6689.40) 50.35(27.74,80.99) 4557.23(2576.92,7504.72) 27.93(15.80,46.00) −1.24(−1.48,−1.00)
Varicella and herpes zoster Republic of Guatemala 160,023.52(156319.47,163790.17) 3258.63(3183.20,3335.33) 152,509.75(149622.29,156362.97) 2305.54(2261.88,2363.79) −1.16(−1.24,−1.09) 1526.59(894.40,2369.72) 31.09(18.21,48.26) 611.39(472.25,801.61) 9.24(7.14,12.12) −3.43(−3.81,−3.05)
Varicella and herpes zoster Republic of Guinea 122,595.89(118087.88,126257.36) 3729.51(3592.37,3840.90) 229,371.26(223925.28,234911.97) 3072.85(2999.89,3147.08) −0.50(−0.57,−0.43) 3733.08(2062.49,6028.91) 113.56(62.74,183.41) 4254.77(2281.36,6639.10) 57.00(30.56,88.94) −1.48(−1.72,−1.24)
Varicella and herpes zoster Republic of Guinea−Bissau 19,990.02(19443.31,20463.25) 3399.11(3306.15,3479.58) 33,843.60(33115.52,34576.58) 3025.74(2960.64,3091.27) −0.17(−0.25,−0.08) 704.62(407.15,1154.46) 119.81(69.23,196.31) 714.85(401.59,1187.12) 63.91(35.90,106.13) −1.37(−1.78,−0.96)
Varicella and herpes zoster Republic of Guyana 11,493.07(10968.25,11936.60) 3011.91(2874.38,3128.15) 7326.40(7048.34,7550.63) 2609.93(2510.87,2689.80) −0.74(−0.98,−0.50) 6.76(4.30,10.16) 1.77(1.13,2.66) 3.21(1.66,5.49) 1.14(0.59,1.96) −1.48(−1.79,−1.17)
Varicella and herpes zoster Republic of Haiti 110,751.65(107358.00,113711.60) 3309.55(3208.14,3398.00) 158,530.93(154114.98,162192.85) 2827.00(2748.25,2892.30) −0.31(−0.40,−0.21) 4957.57(2750.04,7394.30) 148.15(82.18,220.96) 4442.77(2430.03,7170.87) 79.23(43.33,127.87) −1.64(−1.92,−1.37)
Varicella and herpes zoster Republic of Honduras 84,413.84(82392.30,86160.93) 3110.77(3036.28,3175.16) 110,144.85(108445.96,112117.97) 2531.78(2492.73,2577.13) −0.69(−0.76,−0.61) 1362.24(829.90,2114.81) 50.20(30.58,77.93) 741.58(409.52,1207.49) 17.05(9.41,27.76) −3.49(−3.60,−3.38)
Varicella and herpes zoster Republic of Iceland 2224.11(2153.62,2276.08) 2631.70(2548.29,2693.20) 2266.06(2205.86,2322.76) 2543.15(2475.58,2606.78) −0.16(−0.26,−0.07) 1.38(0.72,2.35) 1.64(0.85,2.78) 1.34(0.72,2.26) 1.51(0.81,2.53) −0.26(−0.41,−0.11)
Varicella and herpes zoster Republic of India 11,502,534.38(11010804.32,11872165.22) 2802.65(2682.84,2892.71) 11,250,676.44(10811878.36,11616405.10) 2247.56(2159.90,2320.62) −0.68(−0.70,−0.66) 178,716.36(138472.13,226236.54) 43.55(33.74,55.12) 92,969.59(71085.24,120281.20) 18.57(14.20,24.03) −2.85(−2.98,−2.73)
Varicella and herpes zoster Republic of Indonesia 2,103,257.86(1896278.85,2251273.88) 2404.73(2168.08,2573.96) 2,085,854.80(1892937.88,2223637.95) 2312.02(2098.19,2464.74) −0.08(−0.14,−0.02) 28,945.81(23523.33,36081.91) 33.09(26.90,41.25) 16,373.43(12697.28,20793.87) 18.15(14.07,23.05) −1.83(−2.13,−1.54)
Varicella and herpes zoster Republic of Iraq 311,253.92(296334.55,325426.47) 3022.31(2877.44,3159.93) 435,461.33(421106.20,450410.87) 2469.03(2387.64,2553.79) −0.53(−0.63,−0.43) 2253.53(1407.60,3467.80) 21.88(13.67,33.67) 882.19(546.91,1303.41) 5.00(3.10,7.39) −4.92(−5.25,−4.59)
Varicella and herpes zoster Republic of Italy 287,182.00(280116.88,294067.99) 2108.58(2056.71,2159.14) 222,993.52(215188.69,231671.44) 2127.88(2053.41,2210.69) 0.09(−0.12,0.31) 414.26(323.90,544.13) 3.04(2.38,4.00) 194.89(124.91,299.69) 1.86(1.19,2.86) −1.71(−1.80,−1.61)
Varicella and herpes zoster Republic of Kazakhstan 186,062.95(180626.05,192963.97) 2800.84(2719.00,2904.73) 195,810.49(189973.42,201562.67) 2912.08(2825.27,2997.63) 0.97(0.50,1.45) 113.32(73.69,170.71) 1.71(1.11,2.57) 185.63(120.13,271.21) 2.76(1.79,4.03) 1.57(0.90,2.24)
Varicella and herpes zoster Republic of Kenya 440,996.62(428775.59,451739.77) 3197.52(3108.91,3275.42) 598,521.57(586863.09,614481.94) 2432.97(2385.58,2497.85) −0.76(−0.88,−0.64) 5108.81(4068.74,6517.04) 37.04(29.50,47.25) 6842.19(5448.14,8527.37) 27.81(22.15,34.66) 0.24(−0.25,0.73)
Varicella and herpes zoster Republic of Kiribati 1182.18(1122.71,1226.52) 3225.32(3063.06,3346.28) 1434.60(1383.91,1477.48) 2684.25(2589.40,2764.48) −0.44(−0.58,−0.29) 31.56(19.20,49.05) 86.11(52.40,133.81) 28.42(16.57,45.26) 53.17(31.00,84.69) −1.43(−1.58,−1.28)
Varicella and herpes zoster Republic of Korea 352,263.33(339983.88,362889.19) 2211.72(2134.63,2278.44) 168,842.89(158080.09,179116.75) 2014.05(1885.66,2136.60) −0.38(−0.55,−0.20) 1495.92(964.86,2229.57) 9.39(6.06,14.00) 235.54(148.61,368.14) 2.81(1.77,4.39) −3.48(−3.93,−3.03)
Varicella and herpes zoster Republic of Latvia 19,786.75(19071.15,20783.93) 2629.76(2534.65,2762.29) 9292.26(8965.82,9710.53) 2400.58(2316.25,2508.64) 0.82(0.29,1.36) 75.91(56.47,101.60) 10.09(7.51,13.50) 7.51(5.26,10.30) 1.94(1.36,2.66) −5.28(−6.34,−4.20)
Varicella and herpes zoster Republic of Liberia 48,481.00(47039.90,49775.02) 3548.69(3443.21,3643.41) 77,509.82(75769.93,79554.35) 2778.09(2715.73,2851.37) −0.47(−0.66,−0.27) 1496.39(817.92,2411.74) 109.53(59.87,176.53) 772.96(430.44,1261.36) 27.70(15.43,45.21) −4.72(−5.14,−4.29)
Varicella and herpes zoster Republic of Lithuania 28,604.75(27699.00,29818.91) 2582.50(2500.73,2692.12) 13,028.72(12578.38,13637.94) 2431.67(2347.62,2545.38) 0.35(−0.07,0.78) 12.09(6.84,19.97) 1.09(0.62,1.80) 4.89(2.43,8.33) 0.91(0.45,1.56) −0.69(−1.01,−0.37)
Varicella and herpes zoster Republic of Madagascar 224,846.04(217477.46,231481.00) 3342.95(3233.39,3441.59) 411,016.63(403080.15,421217.69) 2750.42(2697.31,2818.69) −0.60(−0.70,−0.49) 5223.17(3009.62,8130.95) 77.66(44.75,120.89) 6097.50(3631.03,9819.03) 40.80(24.30,65.71) −1.70(−1.87,−1.53)
Varicella and herpes zoster Republic of Malawi 203,804.07(194815.93,212109.06) 3656.80(3495.53,3805.81) 276,214.71(270929.03,282947.44) 2608.05(2558.14,2671.62) −1.12(−1.31,−0.94) 5071.44(2666.84,8330.98) 91.00(47.85,149.48) 4471.13(2353.59,7429.50) 42.22(22.22,70.15) −2.12(−2.50,−1.74)
Varicella and herpes zoster Republic of Maldives 3358.68(2894.58,3791.08) 2616.95(2255.34,2953.85) 2766.64(2366.77,3114.28) 2123.18(1816.31,2389.97) −0.44(−0.71,−0.16) 41.98(24.84,65.26) 32.71(19.35,50.85) 8.05(5.13,11.59) 6.18(3.94,8.89) −5.27(−5.78,−4.75)
Varicella and herpes zoster Republic of Mali 184,750.01(177087.43,190845.79) 3735.44(3580.52,3858.69) 470,323.50(455520.28,483022.66) 3304.44(3200.43,3393.66) −0.40(−0.43,−0.38) 4356.42(2359.97,7066.46) 88.08(47.72,142.88) 6626.24(3661.59,10734.32) 46.56(25.73,75.42) −1.80(−1.98,−1.61)
Varicella and herpes zoster Republic of Malta 2890.63(2813.50,2980.75) 2508.13(2441.21,2586.33) 2231.19(2160.17,2313.50) 2657.57(2572.98,2755.61) 0.39(0.09,0.68) 1.91(1.05,3.27) 1.65(0.91,2.84) 1.33(0.68,2.35) 1.58(0.81,2.79) −0.13(−0.20,−0.06)
Varicella and herpes zoster Republic of Mauritius 9222.41(8058.03,10304.84) 2140.69(1870.42,2391.95) 5866.36(5196.17,6491.09) 1975.84(1750.11,2186.26) −0.42(−0.48,−0.36) 8.56(5.48,12.73) 1.99(1.27,2.96) 3.79(1.85,6.71) 1.28(0.62,2.26) −1.91(−2.91,−0.90)
Varicella and herpes zoster Republic of Moldova 42,242.77(40991.45,44237.00) 2671.43(2592.30,2797.55) 15,501.40(14946.65,16120.20) 2226.44(2146.77,2315.32) 0.29(−0.19,0.78) 15.79(9.20,26.50) 1.00(0.58,1.68) 6.19(3.16,11.20) 0.89(0.45,1.61) −0.01(−0.24,0.22)
Varicella and herpes zoster Republic of Mozambique 255,620.83(247559.63,262817.93) 3376.45(3269.97,3471.51) 523,384.16(513316.64,535034.72) 2947.95(2891.25,3013.58) −0.51(−0.65,−0.38) 9260.44(4580.11,16584.37) 122.32(60.50,219.06) 12,846.74(6982.29,21491.84) 72.36(39.33,121.05) −0.98(−1.34,−0.63)
Varicella and herpes zoster Republic of Namibia 23,256.58(22637.60,23850.03) 3053.33(2972.06,3131.24) 28,086.42(27466.52,28781.44) 2621.50(2563.65,2686.38) −0.36(−0.45,−0.28) 291.02(172.31,456.90) 38.21(22.62,59.99) 266.83(153.14,440.13) 24.91(14.29,41.08) −1.10(−1.29,−0.91)
Varicella and herpes zoster Republic of Nauru 158.16(147.09,165.51) 3035.41(2822.92,3176.47) 138.08(130.97,143.61) 2691.95(2553.40,2799.89) −0.34(−0.41,−0.27) 2.57(1.49,3.95) 49.40(28.62,75.88) 1.64(0.98,2.48) 31.89(19.19,48.30) −1.22(−1.82,−0.61)
Varicella and herpes zoster Republic of Nicaragua 67,021.85(65526.73,68415.41) 2978.40(2911.96,3040.33) 64,463.99(63333.61,65734.18) 2480.09(2436.60,2528.96) −0.38(−0.54,−0.22) 672.06(418.53,992.57) 29.87(18.60,44.11) 266.45(166.55,414.52) 10.25(6.41,15.95) −3.42(−3.58,−3.25)
Varicella and herpes zoster Republic of Niue 25.29(23.62,26.56) 2473.40(2310.91,2597.56) 11.92(11.33,12.38) 2257.01(2145.69,2343.87) −0.12(−0.21,−0.03) 0.26(0.15,0.41) 25.38(14.60,40.05) 0.08(0.05,0.12) 14.85(9.29,21.99) −1.71(−1.78,−1.65)
Varicella and herpes zoster Republic of Palau 147.82(139.23,153.56) 2397.66(2258.29,2490.72) 96.87(92.14,100.87) 2187.56(2080.75,2277.87) −0.37(−0.50,−0.23) 1.17(0.71,1.78) 19.05(11.55,28.83) 0.48(0.30,0.73) 10.81(6.73,16.51) −1.64(−1.77,−1.51)
Varicella and herpes zoster Republic of Panama 28,682.38(28057.71,29191.00) 2638.59(2581.13,2685.38) 36,211.87(35462.90,37159.31) 2402.54(2352.85,2465.40) −0.19(−0.27,−0.11) 265.90(210.10,329.68) 24.46(19.33,30.33) 57.28(42.02,78.12) 3.80(2.79,5.18) −8.19(−9.38,−6.99)
Varicella and herpes zoster Republic of Paraguay 61,635.27(59963.45,62891.83) 2978.85(2898.05,3039.58) 64,738.19(63460.72,66005.14) 2424.05(2376.21,2471.49) −0.53(−0.63,−0.42) 460.75(280.29,687.92) 22.27(13.55,33.25) 299.93(174.45,477.95) 11.23(6.53,17.90) −1.86(−2.00,−1.72)
Varicella and herpes zoster Republic of Peru 293,512.97(282051.55,301624.11) 2756.07(2648.44,2832.23) 327,341.36(314130.41,337605.68) 2616.53(2510.93,2698.58) −0.15(−0.25,−0.06) 3568.49(2142.19,5292.02) 33.51(20.11,49.69) 869.48(521.37,1361.74) 6.95(4.17,10.88) −5.02(−5.20,−4.84)
Varicella and herpes zoster Republic of Poland 295,806.67(286520.59,307091.80) 2376.05(2301.46,2466.70) 187,880.14(181640.83,196199.63) 2440.44(2359.40,2548.51) 0.79(0.46,1.13) 593.37(523.36,681.54) 4.77(4.20,5.47) 97.75(61.74,150.81) 1.27(0.80,1.96) −4.02(−4.78,−3.25)
Varicella and herpes zoster Republic of Rwanda 140,702.43(136990.72,144014.33) 3399.70(3310.01,3479.72) 176,742.42(173029.64,181212.55) 2745.26(2687.59,2814.70) −0.66(−0.73,−0.60) 4962.29(2879.01,8054.01) 119.90(69.56,194.60) 2660.01(1541.94,4175.09) 41.32(23.95,64.85) −3.75(−4.09,−3.41)
Varicella and herpes zoster Republic of San Marino 125.41(122.11,128.95) 2096.36(2041.15,2155.52) 126.87(122.53,131.43) 2033.47(1963.90,2106.54) −0.30(−0.65,0.04) 0.20(0.13,0.30) 3.37(2.24,4.98) 0.14(0.09,0.21) 2.27(1.37,3.43) −1.34(−1.40,−1.29)
Varicella and herpes zoster Republic of Senegal 152,044.71(147235.77,156163.63) 3419.08(3310.94,3511.71) 229,695.15(224315.95,235688.57) 2830.39(2764.11,2904.25) −0.45(−0.54,−0.35) 3636.12(2201.32,5636.32) 81.77(49.50,126.75) 3539.85(2024.42,5455.06) 43.62(24.95,67.22) −1.07(−1.44,−0.69)
Varicella and herpes zoster Republic of Serbia 69,223.44(67642.71,71503.54) 2386.11(2331.62,2464.71) 37,661.13(36481.48,39220.05) 2009.81(1946.85,2093.00) −0.45(−0.56,−0.34) 340.15(206.54,519.53) 11.72(7.12,17.91) 53.89(35.04,77.15) 2.88(1.87,4.12) −4.53(−4.74,−4.32)
Varicella and herpes zoster Republic of Seychelles 690.78(602.97,769.41) 2211.09(1930.01,2462.76) 676.03(583.14,753.72) 2214.46(1910.21,2468.97) 0.12(0.05,0.19) 4.85(3.09,6.99) 15.52(9.89,22.37) 2.42(1.51,3.60) 7.94(4.94,11.80) −1.93(−2.09,−1.78)
Varicella and herpes zoster Republic of Sierra Leone 82,562.84(79002.66,85680.68) 3743.15(3581.74,3884.50) 137,191.48(133405.53,140698.08) 3014.76(2931.56,3091.82) −0.67(−0.71,−0.63) 2017.97(1156.41,3364.66) 91.49(52.43,152.54) 2188.63(1184.55,3823.56) 48.09(26.03,84.02) −2.12(−2.28,−1.97)
Varicella and herpes zoster Republic of Singapore 22,088.17(20130.10,22985.74) 2398.36(2185.75,2495.82) 28,347.68(26806.06,29649.17) 2716.86(2569.11,2841.60) 0.26(−0.06,0.58) 44.33(34.63,56.56) 4.81(3.76,6.14) 17.84(8.78,31.34) 1.71(0.84,3.00) −4.51(−5.18,−3.84)
Varicella and herpes zoster Republic of Slovenia 12,396.24(12010.13,12886.85) 2226.44(2157.09,2314.56) 9815.16(9504.53,10153.29) 2424.56(2347.83,2508.09) 0.99(0.73,1.25) 4.45(2.32,7.92) 0.80(0.42,1.42) 3.06(1.52,5.41) 0.76(0.38,1.34) −0.05(−0.18,0.09)
Varicella and herpes zoster Republic of South Africa 493,358.56(483551.31,505418.21) 2799.72(2744.07,2868.16) 497,234.57(487642.18,510423.96) 2496.41(2448.25,2562.63) −0.02(−0.18,0.13) 5021.90(3934.22,6470.29) 28.50(22.33,36.72) 3179.17(2411.99,4120.17) 15.96(12.11,20.69) −1.65(−1.95,−1.35)
Varicella and herpes zoster Republic of South Sudan 107,165.06(103281.62,110397.83) 3261.19(3143.02,3359.57) 164,467.61(159391.18,169462.34) 2997.22(2904.70,3088.24) −0.34(−0.48,−0.20) 2224.87(1348.25,3465.99) 67.71(41.03,105.48) 3442.90(1896.16,5860.70) 62.74(34.56,106.80) −0.12(−0.47,0.24)
Varicella and herpes zoster Republic of Sudan 356,321.11(341402.26,371427.46) 3225.76(3090.70,3362.51) 569,660.50(552015.09,590369.76) 2665.07(2582.52,2761.96) −0.56(−0.64,−0.47) 5889.26(3370.91,9266.08) 53.32(30.52,83.89) 3504.36(2008.80,5569.81) 16.39(9.40,26.06) −3.32(−3.65,−2.98)
Varicella and herpes zoster Republic of Suriname 4411.22(4300.50,4511.87) 2579.80(2515.05,2638.67) 4469.37(4350.64,4587.79) 2354.12(2291.58,2416.50) −0.19(−0.24,−0.14) 51.97(28.35,78.46) 30.39(16.58,45.89) 32.57(19.02,51.47) 17.16(10.02,27.11) −1.87(−2.06,−1.69)
Varicella and herpes zoster Republic of Tajikistan 94,971.52(91652.80,98278.83) 3303.96(3188.50,3419.01) 134,658.76(130965.11,139146.52) 3022.55(2939.64,3123.28) 0.05(−0.24,0.35) 894.72(543.61,1334.97) 31.13(18.91,46.44) 953.53(516.86,1555.96) 21.40(11.60,34.93) −0.68(−0.83,−0.52)
Varicella and herpes zoster Republic of the Congo 41,102.34(40136.50,42018.53) 3098.12(3025.32,3167.18) 63,601.83(62332.75,65497.30) 2557.53(2506.50,2633.75) −0.38(−0.61,−0.15) 1044.45(584.00,1628.14) 78.73(44.02,122.72) 685.99(382.37,1099.38) 27.58(15.38,44.21) −3.18(−3.55,−2.81)
Varicella and herpes zoster Republic of the Gambia 19,337.92(18626.65,19955.70) 3442.19(3315.58,3552.15) 36,326.05(35385.72,37293.43) 2867.96(2793.72,2944.33) −0.53(−0.63,−0.42) 301.90(160.74,497.62) 53.74(28.61,88.58) 469.95(255.13,768.67) 37.10(20.14,60.69) −1.25(−1.60,−0.89)
Varicella and herpes zoster Republic of the Marshall Islands 738.37(699.72,765.71) 2756.98(2612.64,2859.06) 572.11(548.26,589.18) 2479.67(2376.28,2553.66) −0.21(−0.30,−0.11) 10.90(6.23,16.40) 40.69(23.26,61.24) 7.69(4.27,12.68) 33.32(18.51,54.97) −0.78(−1.22,−0.34)
Varicella and herpes zoster Republic of the Niger 183,610.76(176330.10,190186.18) 3784.54(3634.48,3920.08) 526,272.44(510382.34,540535.46) 3376.41(3274.46,3467.91) −0.50(−0.61,−0.40) 5299.72(2964.69,8746.33) 109.24(61.11,180.28) 8571.23(4502.36,14099.69) 54.99(28.89,90.46) −2.37(−2.69,−2.06)
Varicella and herpes zoster Republic of the Philippines 807,524.70(714741.75,885628.48) 2519.37(2229.90,2763.05) 1,041,064.37(933976.15,1121669.11) 2324.96(2085.81,2504.97) −0.23(−0.25,−0.21) 8932.31(7487.86,10943.13) 27.87(23.36,34.14) 7924.99(6364.73,9742.53) 17.70(14.21,21.76) −1.12(−1.34,−0.90)
Varicella and herpes zoster Republic of the Union of Myanmar 465,523.37(415093.60,503161.79) 2435.86(2171.99,2632.80) 468,088.93(413392.55,514451.52) 2253.88(1990.51,2477.12) −0.21(−0.23,−0.19) 11,526.14(6750.27,18755.37) 60.31(35.32,98.14) 4638.07(2756.86,7159.55) 22.33(13.27,34.47) −3.30(−3.68,−2.91)
Varicella and herpes zoster Republic of Trinidad and Tobago 12,841.89(12264.00,13401.52) 2472.10(2360.85,2579.83) 7978.94(7623.72,8312.59) 2192.11(2094.52,2283.78) 0.38(0.09,0.67) 7.65(4.76,12.25) 1.47(0.92,2.36) 5.10(2.90,8.29) 1.40(0.80,2.28) −0.08(−0.48,0.31)
Varicella and herpes zoster Republic of Tunisia 106,524.12(101986.59,111156.20) 2669.74(2556.02,2785.83) 89,835.12(86272.64,93450.81) 2505.47(2406.11,2606.31) 0.29(0.06,0.51) 689.65(402.99,1111.02) 17.28(10.10,27.84) 172.99(104.76,248.81) 4.82(2.92,6.94) −3.68(−3.84,−3.53)
Varicella and herpes zoster Republic of Turkey 702,332.67(678708.62,728034.57) 2632.27(2543.73,2728.60) 567,162.68(549257.87,590696.57) 2295.07(2222.62,2390.30) −0.22(−0.28,−0.16) 6804.59(4102.66,10915.18) 25.50(15.38,40.91) 1034.86(671.05,1539.20) 4.19(2.72,6.23) −5.82(−6.01,−5.63)
Varicella and herpes zoster Republic of Uganda 378,202.71(359915.78,393853.54) 3672.66(3495.08,3824.64) 739,262.53(719613.79,759430.20) 2963.74(2884.97,3044.60) −0.70(−0.73,−0.67) 5718.88(3083.49,9679.83) 55.54(29.94,94.00) 9532.10(5254.31,16554.56) 38.21(21.06,66.37) −0.95(−1.23,−0.67)
Varicella and herpes zoster Republic of Uzbekistan 334,939.15(323751.59,347293.14) 3137.37(3032.57,3253.08) 382,788.12(370808.48,396786.37) 3035.56(2940.56,3146.57) 0.21(−0.22,0.64) 97.18(49.07,176.18) 0.91(0.46,1.65) 113.23(58.04,198.63) 0.90(0.46,1.58) 0.12(0.06,0.19)
Varicella and herpes zoster Republic of Vanuatu 2630.54(2455.44,2766.59) 3152.31(2942.48,3315.34) 4164.03(3955.17,4308.90) 2824.24(2682.59,2922.50) −0.31(−0.34,−0.29) 31.52(18.44,50.59) 37.78(22.10,60.63) 45.43(26.30,73.45) 30.81(17.84,49.82) −0.29(−0.63,0.06)
Varicella and herpes zoster Republic of Yemen 280,387.59(268726.28,293036.52) 3334.74(3196.04,3485.17) 476,205.75(461820.48,494279.29) 2725.52(2643.19,2828.96) −0.33(−0.51,−0.16) 3501.35(1997.09,5725.92) 41.64(23.75,68.10) 3533.67(2133.50,5604.35) 20.22(12.21,32.08) −2.10(−2.30,−1.89)
Varicella and herpes zoster Republic of Zambia 160,863.82(154535.13,166392.19) 3422.28(3287.64,3539.89) 293,497.59(286746.05,301546.63) 2807.45(2742.87,2884.45) −0.60(−0.71,−0.49) 4583.35(2644.90,7313.39) 97.51(56.27,155.59) 4679.34(2590.25,7535.80) 44.76(24.78,72.08) −2.24(−2.70,−1.78)
Varicella and herpes zoster Republic of Zimbabwe 179,121.17(174043.46,183933.60) 2974.27(2889.95,3054.18) 223,897.83(219638.59,228962.39) 2804.25(2750.90,2867.68) 0.08(−0.02,0.19) 1810.51(1139.60,2793.50) 30.06(18.92,46.39) 3628.19(2113.15,5808.93) 45.44(26.47,72.75) 2.94(2.19,3.70)
Varicella and herpes zoster Romania 175,232.96(169154.37,184219.97) 2335.55(2254.53,2455.33) 94,546.49(92238.87,98577.68) 2339.76(2282.65,2439.52) 0.61(0.38,0.85) 273.49(196.41,382.06) 3.65(2.62,5.09) 39.21(21.99,66.21) 0.97(0.54,1.64) −4.91(−5.46,−4.36)
Varicella and herpes zoster Russian Federation 1,128,366.60(1085760.24,1182931.40) 2497.21(2402.92,2617.97) 758,984.60(729350.31,792396.60) 2246.20(2158.50,2345.08) 1.28(0.70,1.86) 3548.51(3206.48,3913.19) 7.85(7.10,8.66) 2527.69(2193.95,2871.97) 7.48(6.49,8.50) 1.14(0.63,1.64)
Varicella and herpes zoster Saint Kitts and Nevis 464.19(447.35,476.55) 2526.74(2435.08,2594.05) 302.54(290.29,312.99) 2151.49(2064.36,2225.76) −0.68(−0.80,−0.55) 0.54(0.37,0.74) 2.94(2.04,4.04) 0.27(0.17,0.40) 1.94(1.21,2.87) −1.32(−1.42,−1.23)
Varicella and herpes zoster Saint Lucia 1654.61(1395.08,1761.83) 2477.83(2089.17,2638.40) 879.24(826.07,918.36) 2095.51(1968.79,2188.76) −0.69(−0.83,−0.55) 2.61(1.86,3.68) 3.90(2.79,5.52) 1.13(0.77,1.61) 2.69(1.83,3.83) −1.32(−2.03,−0.62)
Varicella and herpes zoster Saint Vincent and the Grenadines 1278.49(1228.65,1318.32) 2378.47(2285.74,2452.56) 714.78(682.02,744.18) 2120.74(2023.54,2207.96) −0.28(−0.36,−0.21) 2.60(2.02,3.40) 4.84(3.76,6.33) 0.49(0.31,0.78) 1.46(0.92,2.32) −0.92(−2.40,0.58)
Varicella and herpes zoster Slovak Republic 41,437.96(40350.82,42992.25) 2360.85(2298.92,2449.41) 28,578.29(27643.38,29795.03) 2549.13(2465.73,2657.66) 0.73(0.45,1.02) 122.74(78.13,178.05) 6.99(4.45,10.14) 32.63(21.10,46.09) 2.91(1.88,4.11) −2.45(−2.70,−2.21)
Varicella and herpes zoster Socialist Republic of Viet Nam 790,431.10(686776.60,885729.17) 2347.80(2039.92,2630.86) 697,416.59(595881.21,785168.58) 2205.69(1884.57,2483.22) 0.04(−0.17,0.25) 7727.38(4819.47,11545.71) 22.95(14.32,34.29) 2307.92(1370.03,3668.89) 7.30(4.33,11.60) −3.10(−3.41,−2.79)
Varicella and herpes zoster Solomon Islands 5925.30(5592.35,6179.08) 3044.60(2873.52,3174.99) 9444.95(8987.97,9797.96) 2855.68(2717.51,2962.41) −0.22(−0.29,−0.15) 102.69(58.78,164.22) 52.77(30.20,84.38) 136.29(77.34,210.71) 41.21(23.38,63.71) −0.72(−1.02,−0.42)
Varicella and herpes zoster State of Eritrea 65,527.80(63764.45,67140.12) 3331.72(3242.06,3413.69) 93,103.30(91175.90,95338.90) 2894.42(2834.50,2963.92) −0.40(−0.45,−0.34) 1739.27(1042.95,2640.21) 88.43(53.03,134.24) 2869.42(1631.23,4619.01) 89.21(50.71,143.60) −0.07(−0.24,0.10)
Varicella and herpes zoster State of Israel 53,830.70(52454.65,55492.33) 2683.07(2614.48,2765.89) 94,498.81(91507.39,97717.27) 2801.27(2712.60,2896.68) 0.26(0.17,0.35) 84.37(61.97,113.94) 4.21(3.09,5.68) 118.25(85.49,165.96) 3.51(2.53,4.92) 0.15(−0.27,0.56)
Varicella and herpes zoster State of Kuwait 19,498.69(18047.81,20774.66) 2842.56(2631.05,3028.57) 26,798.66(25719.80,27886.04) 2446.33(2347.85,2545.59) −0.23(−0.41,−0.06) 7.49(3.68,13.07) 1.09(0.54,1.91) 12.80(6.84,21.76) 1.17(0.62,1.99) 0.23(0.18,0.28)
Varicella and herpes zoster State of Libya 63,208.73(60385.89,65830.08) 2738.34(2616.05,2851.90) 43,887.02(42597.18,45356.16) 2102.35(2040.56,2172.72) −0.66(−0.76,−0.56) 336.07(208.60,528.22) 14.56(9.04,22.88) 136.28(81.26,208.81) 6.53(3.89,10.00) −2.59(−2.83,−2.35)
Varicella and herpes zoster State of Qatar 4921.07(4603.43,5199.89) 3214.72(3007.22,3396.86) 18,093.22(17083.35,18934.52) 3030.22(2861.09,3171.12) 0.13(−0.01,0.27) 18.77(11.32,29.78) 12.26(7.39,19.45) 17.85(11.35,26.08) 2.99(1.90,4.37) −4.38(−4.58,−4.18)
Varicella and herpes zoster Sultanate of Oman 32,154.12(30260.54,33819.20) 3208.05(3019.12,3374.17) 42,118.32(39848.48,44120.77) 2823.26(2671.11,2957.49) 0.12(−0.24,0.48) 184.06(114.00,294.51) 18.36(11.37,29.38) 63.44(42.35,89.70) 4.25(2.84,6.01) −3.69(−4.19,−3.18)
Varicella and herpes zoster Swiss Confederation 40,949.15(39607.04,42193.41) 2596.37(2511.27,2675.26) 45,045.41(43721.01,46572.17) 2555.64(2480.50,2642.26) 0.00(−0.19,0.19) 55.45(40.50,75.52) 3.52(2.57,4.79) 41.62(26.80,62.97) 2.36(1.52,3.57) −1.49(−1.65,−1.33)
Varicella and herpes zoster Syrian Arab Republic 214,810.84(204807.40,223912.72) 2921.83(2785.76,3045.63) 104,872.91(102151.79,107719.15) 1927.78(1877.76,1980.10) −1.32(−1.57,−1.06) 1778.64(1007.35,2818.87) 24.19(13.70,38.34) 503.81(305.19,751.96) 9.26(5.61,13.82) −3.23(−4.02,−2.44)
Varicella and herpes zoster Taiwan (Province of China) 170,256.86(164169.57,174504.39) 2329.43(2246.14,2387.54) 90,728.69(86944.26,95003.39) 2242.73(2149.18,2348.40) −0.18(−0.43,0.07) 307.50(245.16,391.83) 4.21(3.35,5.36) 72.56(43.57,117.75) 1.79(1.08,2.91) −2.90(−3.12,−2.68)
Varicella and herpes zoster Togolese Republic 70,805.42(68695.12,72544.07) 3289.11(3191.08,3369.87) 117,754.64(115097.17,121013.73) 2820.19(2756.55,2898.25) −0.32(−0.43,−0.21) 1299.61(814.08,2049.56) 60.37(37.82,95.21) 1367.15(756.03,2239.34) 32.74(18.11,53.63) −1.68(−1.90,−1.47)
Varicella and herpes zoster Tokelau 19.55(18.46,20.37) 2577.97(2434.68,2686.37) 10.54(9.86,11.16) 2061.02(1927.47,2181.01) −0.59(−0.71,−0.46) 0.24(0.14,0.37) 31.79(18.89,48.54) 0.07(0.04,0.10) 13.21(7.98,20.45) −3.07(−3.30,−2.84)
Varicella and herpes zoster Turkmenistan 58,512.97(56702.28,60556.04) 3103.75(3007.71,3212.12) 54,028.34(52569.23,55970.05) 2755.77(2681.35,2854.81) −0.25(−0.46,−0.05) 21.97(12.95,35.45) 1.17(0.69,1.88) 20.26(11.31,34.44) 1.03(0.58,1.76) −0.35(−0.38,−0.31)
Varicella and herpes zoster Tuvalu 145.85(135.54,154.73) 3413.14(3171.94,3620.97) 127.33(120.55,131.96) 2591.74(2453.71,2685.97) −0.92(−1.04,−0.79) 2.96(1.68,4.67) 69.24(39.20,109.36) 1.13(0.65,1.79) 23.00(13.14,36.52) −3.22(−3.40,−3.04)
Varicella and herpes zoster Ukraine 368,205.11(355759.40,385875.38) 2446.27(2363.58,2563.67) 160,606.44(151998.87,170083.07) 1901.74(1799.82,2013.96) 0.56(−0.01,1.13) 897.37(609.18,1415.15) 5.96(4.05,9.40) 293.46(220.81,380.55) 3.47(2.61,4.51) −0.64(−1.22,−0.06)
Varicella and herpes zoster Union of the Comoros 8573.48(8302.67,8816.67) 3243.63(3141.17,3335.63) 8235.80(8072.54,8436.83) 2623.30(2571.30,2687.33) −0.72(−0.74,−0.71) 221.58(124.74,350.10) 83.83(47.19,132.45) 153.78(84.84,255.33) 48.98(27.02,81.33) −2.05(−2.35,−1.75)
Varicella and herpes zoster United Arab Emirates 22,531.75(21361.80,23515.91) 3186.87(3021.39,3326.07) 43,342.85(41570.23,45337.73) 2556.98(2452.40,2674.66) 0.00(−0.28,0.29) 162.54(93.29,247.55) 22.99(13.19,35.01) 69.61(48.04,98.13) 4.11(2.83,5.79) −5.34(−5.67,−5.02)
Varicella and herpes zoster United Kingdom of Great Britain and Northern Ireland 393,859.06(383597.40,405195.01) 2655.12(2585.94,2731.54) 371,525.32(360996.85,384529.96) 2373.25(2306.00,2456.33) −0.10(−0.26,0.06) 1441.07(1329.09,1588.54) 9.71(8.96,10.71) 673.06(561.99,834.23) 4.30(3.59,5.33) −2.03(−2.46,−1.59)
Varicella and herpes zoster United Mexican States 1,211,834.98(1187989.95,1235910.96) 2794.36(2739.38,2849.88) 974,267.07(956361.48,997904.38) 2257.82(2216.32,2312.60) −0.52(−0.62,−0.42) 14,421.38(13021.21,16153.95) 33.25(30.03,37.25) 3458.64(2773.76,4428.67) 8.02(6.43,10.26) −5.05(−5.75,−4.34)
Varicella and herpes zoster United Republic of Tanzania 503,115.19(484010.43,519402.01) 3371.36(3243.34,3480.49) 892,319.95(870919.73,915742.33) 2891.67(2822.32,2967.58) −0.47(−0.56,−0.39) 11,457.67(6948.69,18008.26) 76.78(46.56,120.67) 14,699.17(8304.59,23700.47) 47.63(26.91,76.80) −0.74(−1.07,−0.41)
Varicella and herpes zoster United States of America 2,010,805.06(1963145.88,2073680.13) 2715.64(2651.27,2800.55) 1,896,457.75(1843805.86,1952706.89) 2332.31(2267.56,2401.49) −0.38(−0.48,−0.29) 4286.28(3867.20,4867.50) 5.79(5.22,6.57) 2904.53(2368.07,3626.15) 3.57(2.91,4.46) −1.25(−1.78,−0.72)
Varicella and herpes zoster United States Virgin Islands 1085.50(1031.04,1119.47) 2602.19(2471.63,2683.62) 389.48(372.18,405.25) 2137.72(2042.78,2224.26) −0.65(−0.70,−0.61) 6.32(3.63,9.50) 15.16(8.70,22.78) 1.22(0.68,2.04) 6.69(3.72,11.21) −2.32(−2.47,−2.17)

Fig. 8.

Fig. 8

Estimated annual percentage change in overall incidence and DALYs of 8 vaccine-preventable diseases in children and adolescents, globally, 1990–2021

The highest incidence of acute hepatitis E is mainly in Asia (South Asia: 721.18 per 100,000, Southeast Asia: 349.53 per 100,000, and East Asia: 719.43 per 100,000)(Table 4, Fig. 7A). The highest incidence of hepatitis B is concentrated in Oceania (970.50 per 100,000), Western Sub-Saharan Africa (1073.00 per 100,000), and Central Sub-Saharan Africa (138 per 100,000). The long-term trend from 1990 to 2021 shows an increasing trajectory of incidence of acute hepatitis E in 42 countries/regions including the Kingdom of Bhutan, the Republic of Turkey, and the Republic of San Marino, with EAPC ranging from 1.02 to 1.18 (Table 5; Fig. 8).

In 2021, pertussis are concentrated in Central Sub-Sahamn Africa (1319.80 per 100,000 population) and Western Sub-Saharan Africa (650.38 per 100,000 population) (Table 4, Fig. 7A). The long-term trend from 1990 to 2021 shows that 10 countries/areas are experiencing an upward trend in growth rates. The top three countries/areas with increasing incidence rates are the Republic of Iceland, Ukraine, and the Republic of San Marino, with EAPCs of 5.24, 4.02, and 2.59, respectively (Table 5; Fig. 8).

South Asia and Oceania had higher incidence rates of typhoid fever in 2021, with 493.19 per 100,000 and 429.65 per 100,000, respectively (Table 4, Fig. 7A). The long-term trend from 1990 to 2021 includes an increase in incidence in countries/regions such as the Republic of Italy, the Republic of Poland, and Hungary, with EAPC ranging from 1.32% to 2.29% (Table 5; Fig. 8).

In 2021, measles was more prevalent in Western Sub-Saharan Africa (728.35 per 100,000) and Eastern Sub-Saharan Africa (606.84 per 100,000) (Table 4, Fig. 7A). The long-term trend from 1990 to 2021 shows an increase in incidence in only two countries, Montenegro and the Republic of Finland. The EAPC is 7.32 and 3.39, respectively (Table 5; Fig. 8).

In 2021, the incidence of Meningitis varied very little between regions, with relatively low incidence rates ranging from 6.09 to 183.75 per 100,000 population (Table 4, Fig. 7A). Moreover, the long-term trend from 1990 to 2021 shows a decreasing trend in all countries/regions (Table 5; Fig. 8).

The regional characterization of DALY rates for the 8 VPDs in 2021 was strongly correlated with incidence patterns, with Eastern Sub-Saharan Africa having the significantly highest DALY rates for all 8 diseases in all regions (Table 4; Fig. 7B). From 1990 to 2021, most regions and countries with increasing incidence of VPDs showed concurrent upward trends in DALY (Table 5; Fig. 8).

To understand the countries/areas where the multiple burden of VPDs increased from 1990 to 2021, we collated countries/areas where the incidence or DALYs of at least two diseases in VPDs increased (Table 6). At the global level, Bulgaria and Ukraine exhibited increasing incidence trends for five of the eight diseases (EAPC = 0.025 to 1.095, 0.12 to 4.1) (Table 5; Table 6). Canada, Sweden, and Zimbabwe showed increasing trends in the rates of DALYs for 4 diseases (EAPC = 0.04 to 0.6,0.11 to 3.05,0.24 to 2.95). Nine countries (Australia, Canada, Czech Republic, Spain, Bulgaria, Finland, Iceland, Zimbabwe, and Ukraine) had increasing trends in the incidence or DALYs of ≥ 2 VPDs. In Zimbabwe, there was a concurrent increase in the incidence and DALYs for Acute hepatitis A, Varicella and herpes zoster, and typhoid fever. EAPCs and burdens in other countries can be found in Fig. 8 (Fig. 8; Fig. 9)

Table 6.

Nations with multiple upward trends in incidence and DALYs among the eight vaccine-preventable Diseases(VPDs)

Nations Number of diseases with an increasing trend in incidence VPDs and corresponding EAPC values Number of diseases with an increasing trend in DALYs VPDs and corresponding EAPC values
Australia 4 Acute hepatitis A: 0.215, Acute hepatitis E: 0.04, Typhoid fever: 0.94, Varicella and herpes zoster: 0.1 2 Acute hepatitis E: 0.13, Typhoid fever: 0.92
Canada 2 Acute hepatitis A: 0.41, Typhoid fever: 0.09 4 Acute hepatitis A: 0.12, Acute hepatitis E: 0.07, Measles: 0.040, Typhoid fever: 0.60
Czech Republic 4 Acute hepatitis A: 0.61, Acute hepatitis E: 0.1, Typhoid fever: 1.31, Varicella and herpes zoster: 1.10 2 Typhoid fever: 13.5, Varicella and herpes zoster: 2.14
Georgia 2 Acute hepatitis A: 0.09, Varicella and herpes zoster: 0.08 2 Measles: 2.37, Varicella and herpes zoster: 0.38
Hellenic Republic 3 Acute hepatitis E: 0.43, Typhoid fever: 0.25, Varicella and herpes zoster: 0.075 2 Acute hepatitis E: 4.68, Varicella and herpes zoster: 0.33
Kingdom of Spain 4 Acute hepatitis A: 0.99, Acute hepatitis E: 0.66, Typhoid fever: 0.32, Varicella and herpes zoster: 0.78 2 Acute hepatitis A: 0.275, Acute hepatitis E: 1.24
Kingdom of Thailand 2 Acute hepatitis A: 0.99, Acute hepatitis E: 0.03, Typhoid fever: 0.375 2 Acute hepatitis A: 0.29, Acute hepatitis E: 0.38
Republic of Bulgaria 5 Acute hepatitis A: 0.53, Acute hepatitis E: 0.02, Pertussis: 0.71, Typhoid fever: 1.10, Varicella and herpes zoster: 0.88 3 Measles: 5.16, Pertussis: 0.79, Varicella and herpes zoster: 0.07
Republic of Finland 2 Measles: 3.48, Typhoid fever: 0.01 2 Acute hepatitis E: 0.32, Measles: 5.10
Republic of Iceland 2 Acute hepatitis A: 0.06, Pertussis: 0.05, Typhoid fever: 0.35 2 Acute hepatitis E: 1.15, Pertussis: 4.73
Republic of Zimbabwe 4 Acute hepatitis A: 0.08, Acute hepatitis E: 0.07, Typhoid fever: 0.18, Varicella and herpes zoster: 0.09 4 Acute hepatitis A: 1.22, Pertussis: 0.24, Typhoid fever: 2.48, Varicella and herpes zoster: 2.95
Russian Federation 3 Acute hepatitis A: 0.04, Acute hepatitis E: 0.065, Typhoid fever: 0.23 2 Acute hepatitis E: 0.15, Varicella and herpes zoster: 1.14
State of Israel 2 Acute hepatitis E: 0.28, Varicella and herpes zoster: 0.26 2 Acute hepatitis E: 3.14, Varicella and herpes zoster: 0.15
Ukraine 5 Acute hepatitis A: 0.32, Acute hepatitis E: 0.12, Pertussis: 4.1, Typhoid fever: 0.31, Varicella and herpes zoster: 0.56 2 Pertussis: 2.02, Typhoid fever: 1.38

Fig. 9.

Fig. 9

Fig. 9

Fig. 9

Fig. 9

Fig. 9

Fig. 9

Fig. 9

Estimated annual percentage changes in incidence and DALYs for each of the 8 vaccine-preventable diseases globally, 1990–2021

SDI and inequality

Overall, most VPDs showed decreasing incidence and DALYs (Table 1; Fig. 10). Significantly, DALYs for hepatitis E in low and medium SDI showed an increasing trend, while incidence rates continued to increase in high SDI, medium-high SDI, and medium SDI regions during 1990–2021 (Table 1). The burden of disease in 2021 was not consistent across different SDI regions (Fig. 11). Overall, with the exception of varicella and herpes zoster, the incidence of most diseases showed a decreasing trend as the SDI increased (Fig. 12).

Fig. 10.

Fig. 10

Fig. 10

Fig. 10

Fig. 10

Global trends in the incidence of eight vaccine-preventable diseases in children and adolescents in different SDI regions, 1990–2021

Fig. 11.

Fig. 11

Incidence and DALYs burden share of 8 vaccine-preventable diseases in different SDI areas in 2021

Fig. 12.

Fig. 12

Fig. 12

Fig. 12

Fig. 12

Relationship between SDI and Incidence of vaccine preventable diseases in 204 countries globally

While the incidence of hepatitis A increased and its DALYs decreased with higher SDI, the opposite trends were observed for hepatitis E.The incidence of hepatitis B increased with a higher SDI, whereas the incidence of hepatitis B decreased with a higher SDI. Hepatitis B, on the other hand, decreases in both incidence and DALYs as SDI increases. The burden of meningitis, varicella and herpes zoster, and other diseases also rose with higher SDI. In contrast, there is no significant linear relationship between DALYs and SDI for typhoid fever (Fig. 13).

Fig. 13.

Fig. 13

Fig. 13

Fig. 13

Fig. 13

Fig. 13

Fig. 13

Fig. 13

Estimated annual percentage changes in incidence of 8 vaccine-preventable diseases in child and adolescent populations and association of SDI and Incidence

Regarding socioeconomic inequality, the SII and CII were calculated for each VPD (Fig. 14). The magnitude of absolute inequality SII varied across diseases, with measles exhibiting the largest relative disparity between low and high SDI populations.

Fig. 14.

Fig. 14

Fig. 14

Fig. 14

Fig. 14

Fig. 14

Fig. 14

Fig. 14

Fig. 14

Health inequality regression curves and concentration curves for eight vaccine-preventable diseases in children and adolescents globally

Discussion

This study provides a comprehensive assessment of the global burden and trends of eight high-incidence VPDs among children and adolescents from 1990 to 2021. The key findings are: (1) a significant overall decline in incidence and DALYs, contrasted by a concerning rise in hepatitis E burden, particularly among males and infants; (2) persistent male predominance and a high burden concentrated in children under 10 years of age; (3) substantial geographical disparities, with the heaviest burdens shifting towards and persisting in low-SDI regions, except for varicella/herpes zoster; (4) a significant inverse association between SDI and disease burden for most VPDs, alongside measurable socioeconomic inequalities.

Global trends and the anomaly of hepatitis E

Despite an annual decline of 2.67% in VPD incidence and 3.15% in DALYs since 1990, our analysis confirms a substantial global decline in the incidence and DALYs of VPDs from 1990 to 2021. However, the 2021 estimates of 231 million incident cases and 72.9 million DALYs underscore that the control of VPDs remains an ongoing public health challenge. The disproportionate burden of hepatitis A, varicella and herpes zoster, and hepatitis E (collectively representing 68% of incident cases) signals gaps in vaccine implementation and pathogen-specific vulnerabilities. Currently, some countries in the Western Pacific region have not incorporated the hepatitis A vaccine into routine immunization [11]. However, given the high incidence of hepatitis A in recent years, health organizations should explore the possibility of eliminating hepatitis A in the region through age-specific precision vaccination, and countries need to develop a strategic and systematic response to emerging outbreaks. Notably, hepatitis E emerged as an epidemiological anomaly. This aligns with evidence linking hepatitis E outbreaks to zoonotic transmission in low-resource settings and insufficient sanitation infrastructure, compounded by the absence of universally adopted pediatric vaccines [12]. The resurgence of hepatitis E post-2009, particularly in South Asia and among males, may reflect climate-related increases in waterborne transmission and sex-based differences in exposure risks. The 2009 inflection point aligning with intensified El Niño events further implicates climate-driven water contamination in tropical zones [4, 13]. Furthermore, socio-behavioral factors may contribute to this disparity. In some Asian contexts, traditional patriarchal norms can influence dietary preferences, favoring male children in meat allocation, and may encourage greater outdoor activity among boys, potentially increasing exposure risks [14]. All of these pathways have the potential to increase hepatitis A and E outbreaks [12]. Recent molecular studies have shed light on the evolving nature of the hepatitis E virus (HEV) [15, 16]. HEV may enhance its transmissibility or pathogenicity, leading to exacerbation of the disease after infection or making it more likely to spread [17]. If the mutated strain is prevalent among adolescents, it may accelerate the spread of the disease. This may partially explain the sustained transmission despite improved sanitation in many regions.

Sex and age disparities

The disparity in VPD burden between males and females—with men having higher frequency and DALYs across most diseases—is like what is seen in the wider field of pediatric infectious disease epidemiology. This could be because of biological factors (like differences in immune response) and social and behavioral risks [18]. The exception of pertussis, where females exhibited marginally higher DALYs, echoes recent studies suggesting sex-specific differences in pathogen susceptibility and sex hormones [19].

Our age-stratified findings expose critical gaps in current vaccine schedules. The concentration of VPD burden in children under 10 years emphasizes the precarious intersection of waning maternal antibodies and incomplete primary immunization. Our age-stratified analysis revealed a critical inflection point: a resurgence in acute hepatitis B incidence among infants (<1 year) after 2018, reversing the previous downward trend. This finding is highly concordant with reports of stagnating or declining coverage of the hepatitis B birth dose, a cornerstone of prevention recommended by WHO within 24 hours of birth. With global coverage at only 43% and as low as 6% in the WHO African Region in 2021, our results provide strong, evidence-based support for the urgent scaling-up of this intervention to interrupt vertical transmission [20]. Meanwhile, the sharp plikely stemsn pertussis aligns with pandemic-era social distancing, indicating non-pharmaceutical interventions temporarily boosted protection. The persistence of this effect will need to be monitored as these measures are eased. Notably, pandemic-related vaccination disruptions reversed trends in older age groups, with increased incidence of pertussis in 1-year-olds and hepatitis A and B in 2–4-year-olds. A survey covering 107 countries showed that in the first few months of the 2020 pandemic, routine immunization services were disrupted or completely suspended in 68 countries [21]. Before the pandemic, the global full-course vaccination rate for the diphtheria-tetanus-pertussis vaccine was approximately 89%-90% [21]. However, a WHO report indicated that the global pertussis vaccination rate has still not recovered to pre-pandemic levels [3]. Therefore, despite the global initiative of The Big Catch Up campaign, there remains a long way to go to achieve the goals of the Immunization Agenda 2030.

Recent advances in maternal immunization strategies offer promising solutions. Currently, more than 30 countries around the world have recommended maternal pertussis vaccination to reduce major infant incidence [22, 23]. Similarly, Riches et al. showed that maternal vaccination against hepatitis B and prophylaxis of infants reduces vertical transmission by 86.3% and has the potential to achieve WHO elimination goals [24]. Therefore, maternal immunization strategies are an important part of reducing the burden of disease in infants and children in the future.

The resurgence of varicella and herpes zoster in 2–4-year-olds presents a complex challenge. Previously, there was a large body of conflicting research on the relationship between varicella vaccination and the incidence of herpes zoster [25–27]. Although recent studies have suggested that varicella vaccination may reduce the incidence of herpes zoster in adults over the age of 10 years, an increase in the incidence of the disease in the 1–2 year age group has been observed in vaccinated children [28–30]. This may be because in young children, the immune response to varicella-zoster virus is inadequate, and therefore viral reactivation can occur earlier [29, 31]. In addition, in vaccinated children, herpes zoster seems to develop at an earlier age [29].

Regional and socioeconomic inequalities

The inverse relationship between SDI and VPD burden—with exceptions like varicella and herpes zoster—reinforces the role of socioeconomic determinants in disease persistence. In addition, on absolute inequality, all except hepatitis E showed varying degrees of reduction, with measles showing the greatest reduction. Measles, whooping cough, hepatitis B, varicella, and herpes zoster all caused more health inequality than the other diseases. Measles inequality was much worse than the other diseases, showing how important it is to focus on improving health services and vaccinations for low-SDL groups. The growing relative inequality for measles (attributable to subnational coverage gaps in low-SDI regions) demands urgent redress through equity-focused immunization strategies, such as Gavi’s zero-dose child initiatives [32]. Further, except for varicella and herpes zoster, the diseases are concentrated in the lower SDI groups. The paradoxical rise of varicella and herpes zoster in high-SDI populations may reflect their waning varicella immunity, supporting expanded recombinant zoster vaccine adoption [33].

The inverse relationship between SDI and hepatitis A incidence illustrates the ‘hygiene-epidemiological transition’: improved sanitation reduces endemic transmission but elevates travel-related exposure risks in high-income populations [34]. In addition, high SDI areas have better disease surveillance systems that capture cases more accurately, leading to higher reporting rates. In contrast, low SDI areas may have underreporting, and actual incidence may be underestimated. Conversely, the 18.5-fold higher meningitis burden in Eastern Sub-Saharan Africa versus Western Europe exposes catastrophic vaccine access disparities. The implementation of the meningococcal A conjugate vaccine in the African meningitis belt has led to the virtual elimination of meningococcal A disease. However, other serotypes have become more important causes of meningitis epidemics [35].

Our findings on the global stagnation and local resurgence of VPDs find a concerning resonance within the European region. In recent years, the vaccination coverage rate in Europe has stagnated and declined in some countries, leading to the resurgence of diseases once thought to be under control [3, 34]. Notably, the WHO European Region reported more than 127,000 cases of measles in 2024, which was the highest number in 27 years [34]. In 2023, pertussis cases reached 87,000, marking the highest level in 29 years [35]. Outbreaks of diphtheria also persist, particularly among vulnerable populations. These outbreaks underscore the critical importance of maintaining high vaccination coverage to protect vulnerable populations, such as infants under one year of age. Although there has been no local wild poliovirus transmission in Europe for over 20 years. However, regular sewage monitoring shows that the risk of virus importation continues to rise, posing a significant threat to groups with insufficient polio vaccination rates [35]. Therefore, continuous monitoring is still necessary. The COVID-19 pandemic severely disrupted routine immunization services and changed Europe’s public health priorities. This led to stagnation or decline in childhood routine vaccination rates, constituting a major emerging public health concern for the region [35]. Beyond pandemic-related disruptions, socio-economic disparities significantly influence vaccine uptake within European countries. Studies conducted in France indicate that vaccination uptake is lower among individuals with lower socioeconomic status, limited education, or non-EU origins [36]. This highlights that vaccine access and acceptance are not uniform, even within a generally high-income region, necessitating targeted interventions for vulnerable groups. In response, European public health groups such as the ECDC and WHO Europe have stressed the need to strengthen health services, ensure equitable access to vaccines, and fight false information [37, 38]. They have played a vital role in coordinating response measures, including conducting catch-up vaccination campaigns and strengthening health system surveillance to address these gaps. The ECDC monitors vaccination coverage and gives scientific guidance to its member states. For example, it recently published reports on Hepatitis B vaccination policy and problems with reaching elimination goals [39]. Addressing these issues is crucial for achieving regional health equity and preventing the further spread of VPDs across Europe.

Limitations and future directions

While our analysis leverages robust GBD methodologies, several limitations merit consideration. First, resource-poor regions face significant monitoring gaps, model-based estimates, and ecological inferences. Passive reporting systems in low SDI regions (e.g., sub-Saharan Africa) tend to underestimate incidence rates, especially for pertussis (atypical manifestations) and hepatitis E (limited diagnostic means). Although GBD mitigates this issue through modelling, residual bias still persists, and uncertainty intervals in data-scarce regions are wider for GBD’s Gaussian process regression. Second, the association between SDI and countries may mask sub-national differences (e.g., urban-rural gaps in India). Third, our analysis period ends in 2021, precluding assessment of post-pandemic recovery efforts in immunization services. Fourth, conflicting research exists on the relationship between varicella vaccination and herpes zoster incidence, and the mechanisms underlying age-specific differences in this association remain unclear. Fifth, the specific mechanisms driving sex-based disparities in VPD burden (e.g., higher pertussis DALYs in females) have not been fully elucidated. Sixth, discrepancies in surveillance capacity between high and low SDI regions may introduce bias in cross-regional burden comparisons.

Future research should prioritize several key areas: (1) Integrate sero-surveillance and genomic data to better disentangle vaccine effects from natural immunity shifts, particularly for evolving pathogens such as HEV. (2) Conduct implementation research to optimize delivery strategies for underutilized vaccines (e.g., hepatitis E) and understand drivers of vaccine hesitancy in specific contexts. (3) Perform in-depth age-specific research on the relationship between varicella vaccination and herpes zoster incidence, focusing on the mechanisms of inadequate immune responses and early viral reactivation in young children. (4) Investigate the specific biological and socio-behavioral mechanisms underlying sex-based disparities in VPD burden, especially for pertussis. (5) Evaluate the long-term effectiveness of equity-focused immunization strategies and maternal immunization programs in reducing VPD burden and health inequalities. (6) Assess the impact of climate change and socio-behavioral factors on the transmission of waterborne and zoonotic VPDs such as hepatitis E, to inform targeted prevention strategies. (7) Strengthen surveillance systems in low SDI regions to reduce underreporting bias and improve cross-regional burden comparisons.

Conclusion

This study confirms substantial global progress in reducing VPD burden from 1990 to 2021, but critical challenges remain, including the rising burden of hepatitis E, persistent sex and age disparities, and significant regional and socioeconomic inequalities. Pandemic-related disruptions to immunization services have further reversed progress in many regions, highlighting the fragility of VPD control. Targeted actions are urgently needed to address these gaps: strengthening perinatal and infant immunization, prioritizing the introduction and expansion of hepatitis E vaccines in endemic regions, implementing equity-focused catch-up campaigns to reach zero-dose children, and restoring and strengthening health systems disrupted by the pandemic. Addressing these issues through coordinated global, regional, and national efforts is essential to achieve the goals of the Immunization Agenda 2030 and advance global health equity in VPD control.

Acknowledgements

We appreciate the excellent work by the Global Burden of Disease Study 2021 collaborators.

Abbreviations

APC

Annual percent change

CII

Concentration index

DTP

Diphtheria-tetanus-pertussis

EAPC

Estimated annual percentage change

EPI

Essential programme on immunization

GBD

Global burden of disease

HEV

Hepatitis e virus

ICD

International classification of diseases

SDI

Sociodemographic index

SII

Slope index of inequality

SDI

Sociodemographic index

VPDs

Vaccine-preventable diseases

WHO

World health organization

Author contributions

All authors contributed to the conceptualization of the study. X.J., R.W., S.T., and S.W. were responsible for methodology, data curation, investigation, formal analysis, writing – original draft, and writing – review and editing. Y.L., F.G., C.Y., and Y.M. were responsible for data curation and investigation. G.S. was responsible for project administration, supervision, funding acquisition and writing – review, and editing. All authors read and approved the final manuscript.

Funding

This study was funded by National center for women and children’s health, NHC, PRC (2024FYH24), Xinjiang Uygur Autonomous Region Health Science and Technology Program Projects (2025001CXKYXM650023079), the Postgraduate Research & Practice Innovation Program of Jiangsu Province (KYCX24_0487), SEU Innovation Capability Enhancement Plan for Doctoral Students (CXJH_SEU 24213) and the Autonomous Region Health Youth Medical Science and Technology Talent Project (WJWY-202457).

Data availability

The data used for the analyses are publicly available from the Global Health Data Exchange GBD Results Tool (https://ghdx.healthdata.org/gbd-results-tool).

Declarations

Ethics approval and consent to participate

Since the data comes from the GBD database, it is not applicable.

Consent for publication

Not applicable.

Competing interests

The authors have no relevant financial or non-financial interests to disclose.

Footnotes

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Contributor Information

Shaokang Wang, Email: shaokangwang@seu.edu.cn.

Ying Ma, Email: ycy720119@163.com.

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Associated Data

This section collects any data citations, data availability statements, or supplementary materials included in this article.

Data Availability Statement

The data used for the analyses are publicly available from the Global Health Data Exchange GBD Results Tool (https://ghdx.healthdata.org/gbd-results-tool).


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