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. 1982 Nov;40(2):163–170. doi: 10.1016/S0006-3495(82)84471-8

Theoretical analysis of specimen cooling rate during impact freezing and liquid-jet freezing of freeze-etch specimens.

G Kopstad, A Elgsaeter
PMCID: PMC1328989  PMID: 7171712

Abstract

We have carried out a theoretical analysis of specimen cooling rate under ideal conditions during impact freezing and liquid-jet freezing. The analysis shows that use of liquid helium instead of liquid nitrogen as cooling medium during impact freezing results in an increase in a specimen cooling rate of no more than 30-40%. We have further shown that when both impact freezing and liquid-jet freezing are conducted at liquid nitrogen temperature, the two methods give approximately the same specimen cooling rate under ideal conditions except for a thin outer layer of the specimen. In this region impact freezing yields the highest cooling rate.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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