Abstract
Introduction
Inadequate access to clinical guidance influences the implementation of evidence-based clinical practices in trauma care settings. This guidance is not optimally effective if it cannot be disseminated in settings where it is most needed, leading to substantial inequities in trauma care. To address this problem, this project developed a trauma clinical guidance repository and accompanying mobile application and sought to elicit concept feedback.
Methods
As part of year 2 of the Design for Implementation: The Future of Trauma Clinical Guidance and Research Conference Series, attendees participated in interactive breakout sessions to generate user feedback and beta-test the clinical guidance repository and mobile phone application that was created after the first conference. A mixed-methods approach using interactive discussions and a post-conference survey was administered to elicit feedback from a largely academic, urban audience.
Results
56 post-conference survey responses were collected. Respondents provided detailed, indepth feedback on the display and user features of the mobile application and gave input on what factors they would prioritize to maximize the tool’s adoption, with the most frequent mentions being about logical and user-friendly application clickthrough. Areas of positive feedback included the repository’s novel contribution as a clinical tool and its potential to aid clinicians in resource-constrained settings. Components of the tool that participants believed required further iteration included ensuring clear, concise language and making it more user-friendly to retrieve information during emergent situations efficiently. A prominent theme throughout the sessions and survey is the necessity of continuous opportunities for feedback from a wide range of stakeholders, both clinical and non-clinical.
Discussion
For novel information dissemination platforms to be effective, clinical guidance must be continuously updated and presented in a user-friendly, logical format that allows clinicians to find and integrate information into practice seamlessly. Conceptual feedback will contribute to a better understanding of clinician needs, further elucidating the opportunities to match technology with bedside utility.
Level of Evidence: Level VI
Keywords: guideline
WHAT IS ALREADY KNOWN ON THIS TOPIC
Disparities in access to timely, resource-relevant, evidence-informed clinical guidance currently lead to inequitable outcomes in trauma care.
WHAT THIS STUDY ADDS
Through interactive sessions, key partners provided input on the key factors that a novel clinical tool would need to address this gap in trauma care successfully.
HOW THIS STUDY MIGHT AFFECT RESEARCH, PRACTICE, OR POLICY
This study further elucidates clinician needs, which will ideally inform ongoing innovation among potential technology partners, ensuring that resources are invested aligned with patient and clinician needs first and foremost.
Introduction
The magnitude of preventable deaths in trauma and emergency care is well-documented, with up to 60% of trauma deaths in certain resource-constrained settings considered potentially preventable due to limitations in available resources.1 Nearly two million lives annually could be saved in low- and middle-income countries with similar care standards as those in higher-income nations.2 However, even within high-income settings, variable quality of implementation of resource-relevant clinical guidance can lead to up to a 60% difference in survival rates.3 Updated evidence-informed clinical guidance is a critical starting point for improving outcomes, but current solutions have a limited and insufficient user interface and user experience (UX). Even well-regarded and widely adopted platforms, including DynaMed, UpToDate, and ClinicalKey, have limitations. For example, when given free licenses, adoption of UpToDate by medical students and faculty in a resource-limited setting was limited by its complex user interface and lack of intuitive features.4 Even so, physicians generally consider UpToDate to be more user-friendly than DynaMed, and UpToDate has been shown to retrieve information more efficiently.5 6 Finally, tools such as UpToDate, which generally provide overviews and literature reviews, are often used in conjunction with well-known clinical practice guidelines in the trauma care space such as the Eastern Association for the Surgery of Trauma Practice Management Guidelines as well as other guidelines such as those provided by the American Association for the Surgery of Trauma and the Western Trauma Association.7,9 While these are tremendous tools for collecting research and guiding clinicians with access to them, they are limited by cost and paywalls, inefficient aggregation of the latest research that occasionally generates contradictory evidence, and lack of a user-friendly series of decision trees that can rapidly be used to aid resource-relevant clinical decision-making.10
Current solutions addressing this space often struggle to strike the right balance between the appropriateness of clinical data and its comprehensiveness, creating tools of doubtful clinical accuracy and utility. Several design factors should be considered to address this issue and create a resource that can collate high-quality, useful information across disciplines. These include continuous input from clinicians and other setting-relevant stakeholders, a regular review process to update guidance and procedures, and adherence to human-centered design principles.11,13 Additionally, to effectively test clinician UX and validate quality and usefulness, current best practices for testing include leadership buy-in to reinforce the reasons for testing, organically providing realistic examples of how the tool could be useful, and lowering barriers to providing feedback throughout the testing process.14,16
Clinical guidance dissemination technology is ripe for innovation, which could be accomplished through building a user-friendly mobile tool that is resource-appropriate, clinically relevant, and continuously updated to be aligned with the latest guidance. The objective of this project is to demonstrate the demand for such a product and to corroborate assumptions around what factors would maximize the product’s adoption by clinicians. Building on previous research in trauma care, this project aims to outline the effective use of a clinical guidance repository and associated mobile app to fill clinical gaps through UX testing with clinicians from several care settings, levels of experience, and parts of the world.
Methods
Minimum viable product deliverable - clinical guidance repository
At the first annual meeting of the Design for Implementation: The Future of Trauma Clinical Guidance and Research (DFI) Conference Series in February 2024, facilitators and conference attendees discussed solutions that would enhance the delivery of timely medical guidance to healthcare providers in emergent situations.17 As part of the minimum viable product (MVP) created, conference participants supported the development of ‘a consolidated, coordinated, accessible (free/offline), easy-to-use platform to house existing guidance—recommended to be used in every hospital, every time, every patient’.
UK-based software firm Tactuum developed a clinical guidance repository and accompanying mobile application to serve as a preliminary solution to the trauma community’s requests. The data sources included in the repository were part of a systematic review which included guidance sources such as protocols, position papers, reviews, guidelines, and consensus documents published from 2016 to 2023.18 These were retrieved from eight databases, including PubMed, Embase, ProQuest, Ovid Medline, Scielo, Google Scholar, and Global Index Medicus, as well as from 28 professional societies affiliated with the International Association for Trauma Surgery and Intensive Care. Guidance sources in the repository were included as published by the original organizations and authors. No contextual modification based on the end-user setting was performed. The initial design of the features used in the Quris Trauma Guidance application incorporated the 2024 DFI conference feedback generated from clinicians, industry leaders, and other stakeholders. Online supplemental item 1 contains an overview of the chatbot feature in the mobile application, as well as example instructions for the model.
As part of the second annual meeting of the DFI Conference Series (February 19–20, 2025), facilitators hosted an interactive workshop focused on beta-testing this application and its corresponding 200+searchable guidance resources, leveraging mixed methods surveys to collect feedback.
Conference facilitation details
During the first day of the conference, facilitators (LB, KG, CC, SR, MB, NF) led participants through several UX breakout sessions, during which participants were provided sticky notes (and virtual equivalents through Miro board) to provide input on various UX facets. Facilitators elicited feedback on several key design and search principles, including information architecture (IA), naming conventions, and content structure. These themes were addressed when leading the group through several features of the mobile application, including the overall IA, the search feature, and an artificial intelligence (AI)-backed chat interface. For this project, IA refers to optimizing the design and structure of information for efficiency of user retrieval, and information hierarchy refers to the specific logic of how links can be clicked on from one page to find more specific information on the next.19 After having participants download the mobile app to their personal Android or Apple iOS device, facilitators presented a virtual poster board (Miro) and prompted application feedback via the hand-written sticky notes (or virtual equivalent). Online supplemental item 2 contains screenshots of the Miro board presentation that include images of the various mobile app displays.
Facilitators collected and organized UX feedback across several flows and application views as detailed in table 1. ‘Tapping through’ indicates an exhaustive walkthrough of all pages and components of the application. The ‘searching’ and ‘Chat UI’ flows denote areas to provide targeted feedback on the search and chat functions of the application, respectively. Beneath each Flow and App View category were several prompt questions for participants to respond to with open-ended text. Example questions included, ‘Were the icons in the document list helpful?’ and ‘What would make this easier to read?’
Table 1. Overview of app views and flows demonstrated during.
| Flow | Information architecture | Chat | |
|---|---|---|---|
| ‘Tapping through’ | ‘Searching’ | ‘Chat UI’ | |
| App views | Home view | Search start | Chat prompt |
| Document list | Search results | Chat response | |
| Document view | |||
| Floating action button | |||
Facilitators (LB, CC, and SR) compiled both virtual and in-person sticky note feedback into a Google Sheet (Google, 2025) immediately after the conference. From there, a reviewer (BF) conducted a thematic analysis using Microsoft Excel (Microsoft Corporation, 2018) by grouping responses into two major categories: ‘IA,’ which includes the ‘tapping through’ and ‘searching’ views in table 1, and ‘chat’, which provides feedback from the ‘Chat UI’ flow in table 1 (Microsoft Corporation, 2018).
Post-conference survey
At the end of the conference, an anonymous 40-question post-conference Microsoft Forms (Microsoft 365, V.2505) survey was sent to participants to collect demographic data and rank order features that would influence their potential adoption and continued use of the Quris application. The survey was released to remote and in-person participants during the last hour of the conference program. Participants were encouraged to complete the survey at that time but also received the link in their email to complete at a time more convenient for them. The last survey response was received on February 28, 2025. When considering that 70 inperson and up to 65 virtual participants joined during the 2 days, and 65 responses were collected, the response rate is close to 48%. However, since the exact number of virtual attendees is unknown, this response rate is not entirely accurate. The rank order question stated, ‘Based on the UX review session for the Tactuum MVP Digital Repository app, what UX features are most important in determining whether or not you use the app? (1=not important, 5=very important).’ The answers were analyzed in Microsoft Excel (Microsoft Corporation, 2018) using univariate descriptive statistics of each answer choice. The Consensus-Based Checklist for Reporting of Survey Studies was used for the post-conference survey (online supplemental item 3).20
Feedback from the breakout sessions and the survey was used as recommendations for iteration and improvement of the Quris application and is the focus of the narrative findings in the Results section.
Results
Demographics of conference attendees
This conference brought together 70 inperson and up to 65 virtual participants during the 2 days. 56 responses were collected from the post-conference survey (table 2). Most survey respondents were clinicians: 46% were physicians, 16% were nurses, and 4% were advanced practice providers. The 34% of non-clinical attendees were from a variety of backgrounds, including patient advocacy roles, the healthcare and life sciences industries, private technology companies, and in clinical research. The majority of clinicians worked in trauma surgery, general surgery, or emergency medicine (75%), and 61% of respondents worked in designated trauma centers. Of these, 71% worked in level I centers, 15% in level II, 9% in level III, and 6% in level IV. More than half of respondents (52%) work under academic appointments, and 13% stated they work in rural areas. A majority of respondents conduct research (52%) and participate in clinical guidance development (70%) at many levels, including internationally (26%), nationally (59%), and institutionally (56%).
Table 2. Demographics of post-conference survey respondents (n=56)*.
| Variable | N | Percent | Variable | N | Percent |
|---|---|---|---|---|---|
| Provider type | Global health initiatives | ||||
| Physician | 26 | 46.4% | Yes | 14 | 25.0% |
| Non-clinical/not applicable | 10 | 17.9% | No | 38 | 67.9% |
| RN | 9 | 16.1% | Not applicable | 4 | 7.1% |
| Other | 9 | 16.1% | Verified/designated trauma center | ||
| Advanced practice providers (APP) | 2 | 3.6% | Yes | 34 | 60.7% |
| Appointment | No | 9 | 16.1% | ||
| Academic | 29 | 51.8% | Not applicable | 13 | 23.2% |
| Non-academic | 19 | 33.9% | Trauma center level | ||
| Other | 8 | 14.3% | Level I | 24 | 70.6% |
| Gender | Level II | 5 | 14.7% | ||
| Woman | 31 | 55.4% | Level III | 3 | 8.8% |
| Man | 23 | 41.1% | Level IV | 2 | 5.9% |
| Transgender | 1 | 1.8% | Clinical discipline | ||
| Prefer not to answer | 1 | 1.8% | Trauma surgery | 21 | 37.5% |
| Age in years | Emergency medicine | 8 | 14.3% | ||
| 25–34 | 4 | 7.1% | General surgery | 13 | 23.2% |
| 35–44 | 17 | 30.4% | Pediatrics | 1 | 1.8% |
| 45–54 | 18 | 32.1% | Burns | 1 | 1.8% |
| 55–64 | 17 | 30.4% | Orthopedics | 1 | 1.8% |
| Race/ethnicity | Neurology | 1 | 1.8% | ||
| White | 44 | 78.6% | Anesthesia | 3 | 5.4% |
| American Indian or Alaska Native | 1 | 1.8% | Physical and rehabilitation medicine | 1 | 1.8% |
| Asian | 5 | 8.9% | Neurosurgery | 2 | 3.6% |
| Black or African American | 4 | 7.1% | Internal medicine | 1 | 1.8% |
| Hispanic | 1 | 1.8% | Other | 5 | 8.9% |
| Prefer not to answer | 1 | 1.8% | Not applicable | 14 | 25.0% |
| Degree | Participating in dissemination science/quality improvement | ||||
| Bachelor of Science and/or Arts | 8 | 14.3% | Yes | 28 | 50.0% |
| Bachelor of Science in Nursing | 3 | 5.4% | No | 23 | 41.1% |
| Master of Science and/or Arts | 8 | 14.3% | Not applicable | 5 | 8.9% |
| Master of Science in Nursing | 7 | 12.5% | |||
| Master of Business Administration | 6 | 10.7% | Conducts research Yes |
29 | 51.8% |
| Master of Public Health | 7 | 12.5% | No | 25 | 44.6% |
| Doctor of Medicine | 26 | 46.4% | Not applicable | 2 | 3.6% |
| Doctor of Philosophy | 7 | 12.5% | Participates in clinical guidance development | ||
| Other | 7 | 12.5% | Yes | 39 | 69.6% |
| None | 1 | 1.8% | No | 13 | 23.2% |
| Rural | Not applicable | 4 | 7.1% | ||
| Yes | 7 | 12.5% | Context of clinical guidance development | ||
| No | 36 | 64.3% | International | 10 | 25.6% |
| Not applicable | 13 | 23.2% | National | 23 | 59.0% |
| Military | Regional | 3 | 7.7% | ||
| Yes | 2 | 3.6% | Institutional | 22 | 56.4% |
| No | 46 | 82.1% | Other | 3 | 7.7% |
| Not applicable | 8 | 14.3% | Role in publishing | ||
| Patient advocate | No/None | 18 | 32.1% | ||
| Yes | 13 | 23.2% | Associate Editor/Editor/Editorial Board | 13 | 23.2% |
| No | 38 | 67.9% | Regular reviewer | 13 | 23.2% |
| Not applicable | 5 | 8.9% | Other | 4 | 7.1% |
| Professional role in diversity, equity, and inclusion initiatives | Not applicable | 8 | 14.3% | ||
| Yes | 9 | 16.1% | |||
| No | 41 | 73.2% | |||
| Not applicable | 6 | 10.7% |
Percentages over 100% are due to rounding error.
Clinical guidance repository feedback session
In total, 377 inperson and 104 virtual sticky notes (n=481) were submitted, providing thematic feedback and content analysis of the Quris mobile application shared during the conference. Of these respondents, the ‘n’ denotes the number of sticky notes that included feedback on a specific area of interest.
Information architecture
UX and design (n=120)
Participants requested standardization of fonts and colors across the application more often than they had a preference for a particular style or user design. Several participants requested that documents include outlines and/or bulleted phrases near the top, with hyperlinks and additional guidance provided further down the page for more evidence or information as needed. While the current application includes downloading external documents as the default, many providers would prefer that the application easily navigate to the document and only use download as a feature if selected by the user. Similarly, many would like the information to all be contained within the application, as opposed to hyperlinks taking the user to an external site. This was particularly relevant to the ‘Access Resource’ (which directs users to the document of interest) feature, with one individual citing skepticism of having to click a link without a clear indication of what it was linking to.
Several users expressed confusion about where feedback from the Floating Action Button would go if they had a question or constructive criticism about the page they were navigating. Others enjoyed the feature’s easy accessibility from several parts of the UX. Finally, many users commented on ways to personalize the application in a positive and clinically sound manner. These include one participant’s request for a ‘personalized folder’ that would allow the application to be more useful to a clinician’s specific feedback, needs, and most probable use cases.
Information hierarchy (n=178)
According to several participants, decision trees as built out in the Quris application should remain in chart form (as is the default across the medical field). Feedback notes about the home view screen indicated that categories (and their corresponding buttons to bring users to the next page) will require concise language that disambiguates between different areas of care. For example, several participants noted that splitting categories (such as geriatric vs adult vs pediatric, by organ system, by practice setting, or even alphabetically) could increase the likelihood of accurately choosing the sought-after page and reduce the number of ‘clicks’ needed to get to the proper protocol. In addition, many individuals emphasized the need for precise language that allows clinicians to use the application in a timely manner, which can be compromised by unclear terms such as ‘general hospital’ guidance.
In terms of the document list, feedback indicated a desire to place documents in a systematic order, such as alphabetically, or, more commonly suggested, anatomically. Simple yet specific titles and phrases were generally considered more favorably when compared with lengthier captions or journal titles. Participants indicated the need to strike a balance between the ability to scan the list quickly and to know what a given document contained before opening it. This feedback was supplemented by frequent comments in support of images or icons corresponding to each potential ‘click’. However, many expressed the importance of using recognizable, universal symbols that do not have a particular meaning in special settings, such as in conflict zones or the Armed Forces.
Participants provided positive feedback on the results from the search tool, indicating it allowed them to logically pursue information with increasing specificity to the topic they wanted to research. One person stated that there was more opportunity to hyperlink to medical groups or other institutions of interest that may be able to provide expertise in a given domain. Finally, a few individuals suggested that the application’s adoption would be easier if a clinician could directly input information about their patient and receive advice tailored to the care of this patient.
Interoperability (n=10)
Some participants highlighted the importance of making all repository features equally user-friendly on smartphone interfaces, given the on-the-go nature of how many clinicians would use the application. Respondents also noted that feedback would need to be efficiently (if not continuously) integrated into the application, given the fast-evolving nature of bedside clinical scenarios and clinical evidence in emergency medical situations. Finally, a few indicated that there would be a need to integrate patient information and documentation to maximize the application’s efficiency.
Chat
UX and design (n=91)
Respondents generally reported that the results and follow-up text from the chat made sense; there were no reports of clear examples of AI-related ‘hallucination’, non sequiturs, or incorrect details. Chat results were deemed somewhat wordy and longer than needed. Still, participants felt comfortable navigating the chat and indicated they would move on and use another area of the application if the results seemed misleading or confusing. A few individuals reiterated the need for continuously updating evidence-informed information to differentiate the application.
Interoperability (n=11)
Participants asked practical questions about the application’s usability in different settings, including resource-limited areas that may not have Internet or phone service. One noted that it would be helpful to link the chat back to a patient registry to reinforce and/or update current guidance on a given topic. Some people noted that in resource-limited settings, a backup strategy for continuously updating information would be critical.
Information hierarchy (n=10)
Feedback on information hierarchy largely mirrored the feedback given for the IA, including input on categorizations. There was some disagreement among responses in terms of what to do with outdated information. Some respondents wanted to keep all information visible for historical reference, whereas others believed it was critical to ‘decommission’ obsolete information. Finally, one individual proposed offering several use cases for a given scenario and suggested a drop-down list within the chat feature.
Post-conference reflection
User-friendliness, graphics and design, evidence-informed and trustworthiness, ability to personalize, clinical relevance, and ethical considerations were all highly important factors influencing the adoption of a bedside-ready clinical guidance tool for those surveyed. Table 3 shows the rank-ordered UX features deemed most important to the respondents of the post-conference survey (on a scale of 1 = ‘not important’ up to 5 = ‘very important’).
Table 3. Rank order of prioritized user experience features.
| Category | Mean | SD |
|---|---|---|
| Intuitive category groupings | 4.05 | 0.92 |
| Intuitive navigation through application | 4.43 | 0.87 |
| Search and sort functionality | 4.55 | 0.78 |
| Broad device compatibility | 4.25 | 0.92 |
| Native text format | 4.38 | 0.84 |
| Enhanced user and group access | 3.88 | 0.99 |
| Ability to bookmark specific sections | 4.00 | 1.06 |
| Ability to create unique user-specific notes | 3.68 | 1.11 |
| Ability to share notes with other users | 3.55 | 1.03 |
| Ability to provide feedback on clinical content | 3.73 | 1.07 |
| Ability to provide feedback on application/UX | 3.59 | 0.99 |
| Dictation/voice content options | 3.75 | 1.07 |
UX, user experience.
Discussion
Contextual inquiry of the Quris Trauma Guidance Repository application, a product intended to provide resource-relevant, efficient, and evidence-informed clinical guidance across a variety of clinical and emergency settings, generated significant interest from participants at the 2025 DFI Conference. Insights on how to improve the UX of this platform uncovered unidentified needs for this product, including more robust ability to be personalized to user needs and logical information architecture. The conference findings also indicated that there is an unmet need for a clinical solution with this level of specificity and personalization. Beyond an openness to incorporating AI into how clinicians synthesize and use the latest clinical evidence, there appears to be tremendous agreement that the current ecosystem and status quo are insufficient.
Models of this sort exist to keep a repository of up-to-date information via serial systematic reviews, which are the current anticipated approach to maintaining the currency of information. These efforts require leveraging in-kind support from partners for whom this offers an attractive opportunity for authorship of the peer-reviewed literature. The more complex question of ongoing maintenance costs of the platform is a topic of subsequent complementary research and includes considerations regarding the economics of the publishing system as well as national-level coordination regarding information dissemination.
Limitations
Feedback from the conference was limited only to its participants; therefore, the takeaways are likely skewed towards clinicians with an interest and/or expertise in this area. The largely US-based, urban academic population represented by the conference participants may not fully represent the views and needs of clinicians in other settings, including in lower-resourced global settings.
Next steps
Results and feedback generated during this conference captured reflection on the first attempt to co-design and beta-test a solution to the problems that were defined during the first year of the conference series and move from an MVP to a more developed interface. In doing so, development can account for common pain points and other areas of clinical feedback from the conference. Even beyond the next stage of building out the UX and underlying clinical evidence, input from healthcare workers and other users will be critical to refine it further. To do this effectively, an organizing framework such as dissemination and implementation research should be used to scale and improve the concept in a sustainable manner. This framework provides guiding principles that health organizations have successfully adopted to implement new practices and technological solutions specific to their organizational needs, reflecting the needs for successful implementation of this project.21
Conclusions
There is a need for an accessible, affordable, clinician co-designed medical information dissemination platform that can seamlessly provide situation-dependent and resource-dependent clinical guidance. If done appropriately and with continued feedback from stakeholders across the design and implementation process, such a tool could be useful in closing gaps in trauma care outcomes globally.
Supplementary material
Footnotes
Funding: The Design for Implementation: The Future of Trauma Research & Clinical Guidance (DFI) conference series was made possible, in part, by a conference grant from the Agency for Healthcare Research and Quality (1R13HS028940-01A1). The views expressed in written conference materials or publications and by speakers and moderators do not necessarily reflect the official policies of the Department of Health and Human Services; nor does mention of trade names, commercial practices, or organizations imply endorsement by the U.S. Government. The American Association for the Surgery of Trauma, American Burn Association, American Trauma Society, Eastern Association for the Surgery of Trauma, Chest Wall Injury Society, Society of Critical Care Medicine, Society of Trauma Nurses, and Trauma Center Association of America provided travel funds for representatives to attend the 2025 DFI meeting. The Eastern Association for the Surgery of Trauma and American Trauma Society provided travel funds for patient partners to attend. The Society of Trauma Nurses, Acera Surgical, and Tactuum provided additional financial support. The American College of Surgeons hosted the event in its Chicago offices and provided meeting management, facilities, and audiovisual equipment at no cost to the conference. Publication of this supplement is made possible by Medical Center of the Rockies, UCHealth (Loveland, Colorado, United States).
Provenance and peer review: Not commissioned; externally peer-reviewed.
Patient consent for publication: Not applicable.
Ethics approval: This study involves human participants. The study was reviewed by the Colorado Multiple Institutional Review Board, CB F490; COMIRB No: 24-1608 and COMIRB #: 22-0626, and determined exempt from institutional review board review because it was deemed Category 2. Category 2 reads, “Research that only includes interactions involving educational tests (cognitive, diagnostic, aptitude, achievement), survey procedures, interview procedures, or observation of public behavior (including visual or auditory recording) if at least one of the following criteria is met: (A) the information obtained is recorded by the investigator in such a manner that the identity of the human subjects cannot readily be ascertained, directly or through identifiers linked to the subjects; (B) any disclosure of the human subjects’ responses outside the research would not reasonably place the subjects at risk of criminal or civil liability or be damaging to the subjects’ financial standing, employability, educational advancement, or reputation or (C) the information obtained is recorded by the investigator in such a manner that the identity of the human subjects can readily be ascertained, directly or through identifiers linked to the subjects, and an IRB conducts a limited IRB review to make the determination required by 45 CFR 46.111(a)(7).” Participants gave informed consent to participate in the study before taking part.
Data availability free text: A limited, deidentified dataset is available upon reasonable request to the corresponding author.
Collaborators: Pamela Bixby, MA, Deputy Director; Coalition for National Trauma Research; San Antonio, TX, USA. Stephanie Bonne, MD, Professor of Surgery; Advocate Christ Medical Center, Department of Surgery, Oak Lawn, IL, USA and Professor of Surgery; Wake Forest School of Medicine, Department of Surgery, Winston-Salem, NC, USA. Eileen M. Bulger, MD, Professor of Surgery & Division Chief, Trauma, Burns, and Critical Care; University of Washington, Seattle, WA, USA and Chief of Surgery; Harborview Medical Center, Seattle, WA, USA. James G Cain, MD, MBA, Department Chair and Professor of Anesthesiology; University of Florida College of Medicine Jacksonville, Department of Anesthesiology, Jacksonville, FL, USA. Jennifer Chastek, DNAP, Certified Registered Nurse Anesthetist; Iowa Anesthesia LC, Manchester, IA, USA. Julia Roberts Coleman, MD, MPH, Assistant Professor; Department of Surgery, Columbus, OH, USA. Todd W Costantini, MD, Professor of Surgery; Division of Critical Care and Acute Care Surgery, University of Minnesota Medical School, Minneapolis, MN, USA. Nicholas Cozzi, MD, MBA, FACEP, FAEMS, Assistant Professor; Rush University Medical Center, Chicago, IL, USA. Kimberly A. Davis, MD, MBA, Division Chief, General Surgery, Trauma and Surgical Critical Care; Yale School of Medicine Department of Surgery, New Haven, CT, USA. Rochelle A. Dicker, MD, Professor of Surgery; UCSF, San Francisco, CA, USA. Warren C. Dorlac, MD, Vice Chair, COT; University of Colorado; Associate Trauma Medical Director, Medical Center of the Rockies, Loveland, CO, USA. Erik Van Eaton, MD, Associate Professor; Department of Surgery, University of Washington, Seattle, WA, USA. Evert Eriksson, MD, Professor of Surgery; Medical University of South Carolina, Department of Surgery, Charleston, SC, USA. Susan Evans, MD, MBA, Professor of Surgery; Wake Forest School of Medicine; Vice Chair Research, Department of Surgery, Winston-Salem, NC, USA. Atrium Health. Shannon Marie Foster, MD, Acute Care Surgeon, Contractor, Director; SMF Coverage & Solutions LLC, Reading, PA, USA. Jeffrey M. Goodloe, MD, Professor; University of OK School of Community Medicine; Department of Emergency Medicine; Tulsa, OK, USA and National Liaison to ACS COT; Board Member; American College of Emergency Physicians; Irving, TX, USA. Elliott R. Haut, MD, PhD, Professor; Johns Hopkins University School of Medicine; Baltimore, MD, USA. Molly Jarman, PhD, MPH, Lead Investigator; Center for Surgery and Public Health, Brigham and Women's Hospital, Boston, MA, USA and Assistant Professor, Department of Surgery, Harvard Medical School, Boston, MA, USA. Alyssa Johnson, MSN, RN, TCRN, CEN, Montana Trauma System Manager; Dept. of Public Health & Human Services, Helena, MT, USA. Meera Kotagal, MD, MPH, Assistant Professor, Division of Pediatric General and Thoracic Surgery; Cincinnati Children's Hospital, Cincinnati, OH, USA and Assistant Professor, Department of Surgery; University of Cincinnati College of Medicine, Cincinnati, OH, USA. Morgan Krause, MSN-Ed, Trauma Nurse Research Coordinator; Northeast Georgia Medical Center, Gainesville, GA, USA. John C. Kubasiak, MD, Assistant Professor of Surgery; Loyola University Chicago, Maywood, IL, USA. Kelly Lang, BA, Author, Speaker, Advocate; The Miracle Child; Leesburg, VA, USA Allison Barbara Leigh, MD candidate, Medical Student; University of Colorado School of Medicine's Fort Collins Branch, Aurora, CO, USA Halinder S. Mangat, MD, MSc, Associate Professor; Kansas University Medical Center, Kansas City, KS, USA and Director of Research; Brain Trauma Foundation, Palo Alto, CA, USA. Debra Marie Marvel, MA, Patient Representative; R Adams Cowley Shock Trauma Center, Baltimore, MD, USA and Patient Advocate, CNTR, San Antonio, Texas, USA. Christopher Paul Michetti, MD, Chief of Trauma, Professor of Surgery; University of Maryland Capital Region Medical Center, Department of Surgery, Largo, MD, USA. Vicki Moran, PhD, RN, Associate Professor of Nursing; Saint Louis University; St. Louis, MO, USA and Trauma Research Coordinator; SSM Health Saint Louis University Hospital, MO, USA. Ashley N. Moreno, MS, Research Associate; Coalition for National Trauma Research; San Antonio, TX, USA. Simon JW Oczkowski, MD MSc MHSc, Associate Professor; Department of Medicine, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Canada. Michael A. Person, MD, MPH, Associate Professor; University of South Dakota; Sioux Falls, SD, USA. Michelle A. Price, PhD, Med, Executive Director; Coalition for National Trauma Research; San Antonio, TX, USA and Adjunct Professor; UT Health San Antonio, TX, USA. LJ Punch, MD, Medical Director; The Bullet Related Injury Clinic, St. Louis, MO, USA. Megan Racey, PhD; Research Coordinator, McMaster University, Hamilton, Ontario, Canada. Bradford L. Ray, CCP, RABT, Director. Patient Blood Management & Research; University Medical Center, El Paso, Texas, USA and Clinical Instructor; Trauma, General Surgery El Paso, Texas, USA. Diane Redmond, MSN RN TCRN CPHQ CCRP, Trauma- Clinical Research Nurse; Penrose Hospital, Trauma Services, Colorado Springs, CO, USA. Linda Kate Reinhart, MSN, CNS; Trauma Program Manager, St. Luke's University Health Network-Grand View Campus, Sellersville, PA, USA and Past President, Society of Trauma Nurses Organization, Lexington, KY, USA. Heather Rhodes, PhD, DHS, RT(R)(ARRT)CT, Trauma Scientist; Center for Clinical Epidemiology and Population Health, Marshfield, WI, USA. Bryn Rhodes, Director of Standards Strategy; Smile Digital Health, Toronto, ON, USA. Andres M. Rubiano, MD, PhD, Professor of Neurosciences and Neurosurgery; Universidad El Bosque, Bogota, Colombia and Medical and Research Director; Meditech Foundation, Cali, Colombia. Sabrina Sanchez, MD, MPH, Associate Professor of Surgery; Boston University Chobanian & Avedisian School of Medicine, Boston, MA, USA and Attending Surgeon, Boston Medical Center, Boston, MA, USA. Babak Sarani, MD, Professor of Surgery and Emergency Medicine; George Washington University, Washington, DC, USA. Erica Shelton, MD, MPH, MHS, Assistant Professor; Department of Emergency Medicine, Johns Hopkins University; Baltimore, MD, USA. David A Spain, MD, Professor of Surgery; Stanford University, Stanford, CA, USA. Kristan Staudenmayer, MD, MS, Associate Professor of Surgery; Stanford University, Stanford, CA, USA and Chair, ACS COT Trauma Systems; COT, Chicago, IL, USA. Deborah M. Stein, MD, MPH, Professor of Surgery; University of Maryland School of Medicine Program in Trauma, Baltimore, MD, USA. Julie Valenzuela, MD, Assistant Professor of Surgery; University of Miami Miller School of Medicine, Surgery, Miami, FL, USA and Director of Community Engaged Research, Outreach, and Advocacy, William Lehman Injury Research Center. Cynthia Lizette Villarreal, MA, Director of Applied Research; Coalition for National Trauma Research; San Antonio, TX, USA. Jeffrey L. Wells, AA, Non-Scientist IRB Member; Univ. MD, Baltimore, USA and Non-Scientist IRB Member; NIH Bethesda, MD, USA. Gabriela Zavala Wong, MD, Research Scientist; Medical Center of the Rockies, UCHealth, Loveland, CO, USA. Sociedad de Cirujanos Generales del Peru, Lima, Peru; Universidad Peruana Cayetano Heredia School of Medicine, Lima, Peru; LeAnne Sitari Young, MSN, RN, TCRN, Assistant Clinical Director of Trauma and Injury Prevention; Texas Children's Hospital, Trauma Services, Houston, TX, USA and Immediate Past President; Society of Trauma Nurses.
Contributor Information
The 2025 Design for Implementation (DFI) Authorship Group:
Pamela Bixby, Stephanie Bonne, Eileen M Bulger, Elliott R Haut, Molly Jarman, Alyssa Johnson, Allison Barbara Leigh, Halinder S Mangat, Debra Marie Marvel, Christopher Paul Michetti, Vicki Moran, Ashley N Moreno, Simon JW Oczkowski, Michael A Person, Michelle A Price, LJ Punch, Bradford L Ray, David A Spain, Kristan Staudenmayer, Deborah M Stein, Julie Valenzuela, Cynthia Lizette Villarreal, Jeffrey L Wells, Gabriela Zavala Wong, LeAnne Sitari Young, James G Cain, Jennifer Chastek, Julia Roberts Coleman, Todd W Costantini, Nicholas Cozzi, Kimberly A Davis, Rochelle A Dicker, Warren C Dorlac, Erik Van Eaton, Evert Eriksson, Susan Evans, Shannon Marie Foster, Jeffrey M Goodloe, Meera Kotagal, Morgan Krause, John C Kubasiak, Kelly Lang, Megan Racey, Diane Redmond, Linda Kate Reinhart, Heather Rhodes, Bryn Rhodes, Andres M Rubiano, Sabrina Sanchez, Babak Sarani, and Erica Shelton
Data availability statement
Data are available upon reasonable request.
References
- 1.Yeboah D, Mock C, Karikari P, Agyei-Baffour P, Donkor P, Ebel B. Minimizing preventable trauma deaths in a limited-resource setting: a test-case of a multidisciplinary panel review approach at the Komfo Anokye Teaching Hospital in Ghana. World J Surg. 2014;38:1707–12. doi: 10.1007/s00268-014-2452-z. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2.Mock C, Joshipura M, Arreola-Risa C, Quansah R. An estimate of the number of lives that could be saved through improvements in trauma care globally. World J Surg. 2012;36:959–63. doi: 10.1007/s00268-012-1459-6. [DOI] [PubMed] [Google Scholar]
- 3.Lee Y, Bahn S, Shin GW, Jung M-Y, Park T, Cho I, Lee J-H. Development of safety and usability guideline for clinical information system. Medicine (Baltimore) 2021;100:e25276. doi: 10.1097/MD.0000000000025276. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Kinengyere AA, Rosenberg J, Pickard O, Kamya M. Utilization and uptake of the UpToDate clinical decision support tool at the Makerere University College of Health Sciences (MakCHS), Uganda. Afr Health Sci. 2021;21:904–11. doi: 10.4314/ahs.v21i2.52. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 5.Baxter SL, Lander L, Clay B, Bell J, Hansen K, Walker A, Tai-Seale M. Comparing the Use of DynaMed and UpToDate by Physician Trainees in Clinical Decision-Making: A Randomized Crossover Trial. Appl Clin Inform. 2022;13:139–47. doi: 10.1055/s-0041-1742216. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 6.Bradley-Ridout G, Nekolaichuk E, Jamieson T, Jones C, Morson N, Chuang R, Springall E. UpToDate versus DynaMed: a cross-sectional study comparing the speed and accuracy of two point-of-care information tools. J Med Libr Assoc. 2021;109:382–7. doi: 10.5195/jmla.2021.1176. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 7.Haut ER. Eastern Association for the Surgery of Trauma (EAST) practice management guidelines and the perpetual quest for excellence. J Trauma Acute Care Surg. 2020;89:1–10. doi: 10.1097/TA.0000000000002709. [DOI] [PubMed] [Google Scholar]
- 8.LaGrone LN, Stein D, Cribari C, Kaups K, Harris C, Miller AN, Smith B, Dutton R, Bulger E, Napolitano LM. American Association for the Surgery of Trauma/American College of Surgeons Committee on Trauma: Clinical protocol for damage-control resuscitation for the adult trauma patient. J Trauma Acute Care Surg. 2024;96:510–20. doi: 10.1097/TA.0000000000004088. [DOI] [PubMed] [Google Scholar]
- 9.Tesoriero R, Coimbra R, Biffl WL, Burlew CC, Croft CA, Fox C, Hartwell JL, Keric N, Lorenzo M, Martin MJ, et al. Adult emergency resuscitative thoracotomy: A Western Trauma Association clinical decisions algorithm. J Trauma Acute Care Surg. 2024;97:961–8. doi: 10.1097/TA.0000000000004462. [DOI] [PubMed] [Google Scholar]
- 10.Uribe-Cavero LJ, Vera-Maccha PJ, Siguas-Huasasquiche A, Bohorquez-Espino EE, Taype-Rondan A. Inconsistent Reporting of Interactions Between Warfarin and Medicinal Plants Across Clinical Decision Support Resources. J Evid Based Integr Med. 2025;30:2515690X251334445. doi: 10.1177/2515690X251334445. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 11.Greenberg JK, Otun A, Kyaw PT, Carpenter CR, Brownson RC, Kuppermann N, Limbrick DD, Jr, Foraker RE, Yen PY. Usability and Acceptability of Clinical Decision Support Based on the KIIDS-TBI Tool for Children with Mild Traumatic Brain Injuries and Intracranial Injuries. Appl Clin Inform. 2022;13:456–67. doi: 10.1055/s-0042-1745829. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 12.Bérubé M, Lapierre A, Sykes M, Grimshaw J, Turgeon AF, Lauzier F, Taljaard M, Stelfox HT, Witteman H, Berthelot S, et al. Canadian Traumatic Brain Injury Research Consortium (2025). Development and usability testing of a multifaceted intervention to reduce low-value injury care. BMC Health Serv Res. 2025;25:37. doi: 10.1186/s12913-024-12153-y. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 13.Thomas A, Asnes A, Libby K, Hsiao A, Tiyyagura G. Developing and Testing the Usability of a Novel Child Abuse Clinical Decision Support System: Mixed Methods Study. J Med Internet Res. 2024;26:e51058. doi: 10.2196/51058. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 14.Meidani Z, Omidvar A, Akbari H, Asghari F, Khajouei R, Nazemi Z, Nabovati E, Holl F. Evaluating the Usability and Quality of a Clinical Mobile App for Assisting Physicians in Head Computed Tomography Scan Ordering: Mixed Methods Study. JMIR Hum Factors. 2024;11:e55790. doi: 10.2196/55790. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.Aiyegbusi OL. Key methodological considerations for usability testing of electronic patient-reported outcome (ePRO) systems. Qual Life Res. 2020;29:325–33. doi: 10.1007/s11136-019-02329-z. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 16.Cresswell KM, Bates DW, Sheikh A. Ten key considerations for the successful implementation and adoption of large-scale health information technology. J Am Med Inform Assoc. 2013;20:e9–13. doi: 10.1136/amiajnl-2013-001684. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 17.Guido JM, Krause M, Steiner A, Nicol A, Grider KT, Zavala Wong G, Moreno AN, LaGrone LN, Design for Implementation (DFI) Authorship Group Trauma community clinical guidance needs: a mixed-methods iterative consensus-building study. Trauma Surg Acute Care Open. 2025;10:e001592. doi: 10.1136/tsaco-2024-001592. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.Zavala Wong G, Panshin MS, Samsamshariat T, Albirair M, Gamboa JE, Simmons CG, Farley AD, LaGrone LN. Dissecting inequity: global systematic review of trauma clinical guidance. Trauma Surg Acute Care Open. 2025;10:e001624. doi: 10.1136/tsaco-2024-001624. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 19.Dekkers T, Melles M, Vehmeijer SBW, de Ridder H. Effects of Information Architecture on the Effectiveness and User Experience of Web-Based Patient Education in Middle-Aged and Older Adults: Online Randomized Experiment. J Med Internet Res. 2021;23:e15846. doi: 10.2196/15846. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 20.Sharma A, Minh Duc NT, Luu Lam Thang T, Nam NH, Ng SJ, Abbas KS, Huy NT, Marušić A, Paul CL, Kwok J, et al. A Consensus-Based Checklist for Reporting of Survey Studies (CROSS) J Gen Intern Med. 2021;36:3179–87. doi: 10.1007/s11606-021-06737-1. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 21.Kwan BM, Brownson RC, Glasgow RE, Morrato EH, Luke DA. Designing for Dissemination and Sustainability to Promote Equitable Impacts on Health. Annu Rev Public Health. 2022;43:331–53. doi: 10.1146/annurev-publhealth-052220-112457. [DOI] [PMC free article] [PubMed] [Google Scholar]
Associated Data
This section collects any data citations, data availability statements, or supplementary materials included in this article.
Supplementary Materials
Data Availability Statement
Data are available upon reasonable request.
