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. 1987 Apr;51(4):557–568. doi: 10.1016/S0006-3495(87)83381-7

Electric and magnetic fields from two-dimensional anisotropic bisyncytia.

N G Sepulveda, J P Wikswo Jr
PMCID: PMC1329928  PMID: 3580484

Abstract

Cardiac tissue can be considered macroscopically as a bidomain, anisotropic conductor in which simple depolarization wavefronts produce complex current distributions. Since such distributions may be difficult to measure using electrical techniques, we have developed a mathematical model to determine the feasibility of magnetic localization of these currents. By applying the finite element method to an idealized two-dimensional bisyncytium with anisotropic conductivities, we have calculated the intracellular and extracellular potentials, the current distributions, and the magnetic fields for a circular depolarization wavefront. The calculated magnetic field 1 mm from the tissue is well within the sensitivity of a SQUID magnetometer. Our results show that complex bisyncytial current patterns can be studied magnetically, and these studies should provide valuable insight regarding the electrical anisotropy of cardiac tissue.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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