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. 1988 Mar;53(3):349–359. doi: 10.1016/S0006-3495(88)83112-6

On the elasticity of cytoskeletal networks.

R Nossal 1
PMCID: PMC1330203  PMID: 3349131

Abstract

Models relating to the gelation and elasticity of complex cytoskeletal networks are formulated and investigated. Kinetic equations for reversible elongation of nucleated actin filaments are analyzed when the filaments are acted upon by capping proteins and cross-linking factors. Analytical expressions are obtained that relate the low frequency elastic shear modulus of a network, G, to chain growth kinetics, the number of nucleation sites, monomer concentration, and the amount of capping and cross-linking protein. Elasticity curves that relate G to such factors as the association constant for cross-linking are derived and then used to determine solation-gelation phase contours.

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Selected References

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