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[Preprint]. 2026 Jun 15:2026.06.10.731422. [Version 1] doi: 10.64898/2026.06.10.731422

Scout-based Multi-Echo NAvigator (SMENA) for high temporal resolution motion and B 0 estimation and correction: applications to multi-echo GRE and EPTI

Nan Wang, Yimeng Lin, Yannick Brackenier, Aizada Nurdinova, Zihan Zhou, Daniel Abraham, Xiaozhi Cao, Congyu Liao, Kawin Setsompop
PMCID: PMC13308255  PMID: 42367951

Abstract

Purpose

To develop a data-driven technique, Scout-based Multi-Echo NAvigator (SMENA), for joint estimation of motion and B 0 inhomogeneity ( δ B 0 ) at a temporal resolution of ∼200 ms with minimal additional scan time for gradient-echo acquisition.

Methods

SMENA consists of two key acquisition components: SMENA-scout and SMENA-nav. SMENA-scout is a rapid 3D 4-mm multi-echo acquisition completed in less than 8 seconds, providing images with matched contrast and phase at multiple echo times. SMENA-nav captures signal variations induced by motion and δ B 0 during the scan using compact multi-echo navigator trajectories (3.5 ms) embedded within each TR. Motion and δ B 0 maps were jointly estimated every ∼200 ms through a model-based optimization framework relating SMENA-scout to SMENA-nav. The estimation accuracy and correction performance of SMENA were evaluated in simulations and in vivo using multi-echo GRE and GRE-EPTI acquisitions. Multiple prospective motion experiments, including large continuous movement and deep breathing, were investigated.

Results

In both simulations and in vivo experiments, accurate motion and δ B 0 estimation were achieved. Compared with motion-only estimation, joint estimation reduced rotation and translation errors. Joint motion and δ B 0 correction resulted in substantial improvements in image quality, particularly at longer echo times, producing an NRMSE of 10.4% compared to 31.6% with motion-only correction. High-temporal-resolution tracking of motion and δ B 0 enabled improved reconstruction quality in scenarios involving continuous motion and deep breathing.

Conclusion

SMENA enables high-temporal-resolution joint estimation of motion and δ B 0 with minimal additional acquisition cost, providing a practical solution for motion- and δ B 0 -robust MRI.

Full Text Availability

The license terms selected by the author(s) for this preprint version do not permit archiving in PMC. The full text is available from the preprint server.


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