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. 1972 Dec;227(3):801–814. doi: 10.1113/jphysiol.1972.sp010059

The role of circulating catecholamines in sweat production in man

Judith A Allen, I C Roddie
PMCID: PMC1331287  PMID: 4650937

Abstract

1. The effects of intravenous infusions of adrenaline, isoprenaline and noradrenaline on human sweating were assessed by continuous measurement of total body weight loss in normal subjects.

2. All three catecholamines increased the rate of weight loss but isoprenaline was effective in a much smaller dosage than either adrenaline or noradrenaline.

3. β-adrenoceptor blockade with propranolol reduced the response.

4. The response was not abolished by collecting expired air in a Douglas bag suggesting that it was not due to an increase in respiratory water loss.

5. The response was not abolished by atropine infusions suggesting that it was not mediated through cholinergic sudomotor nerves.

6. It is concluded that intravenous infusions of catecholamines may elicit a small, non-cholinergically mediated sweat response in man.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allen J. A., Grimley J. F., Roddie I. C. A body balance to measure sweat rates in man. Biomed Eng. 1971 Oct;6(10):468–471. [PubMed] [Google Scholar]
  2. CHALMERS T. M., KEELE C. A. Physiological significance of the sweat response to adrenaline in man. J Physiol. 1951 Aug;114(4):510–514. doi: 10.1113/jphysiol.1951.sp004640. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. CHALMERS T. M., KEELE C. A. The nervous and chemical control of sweating. Br J Dermatol. 1952 Feb;64(2):43–54. doi: 10.1111/j.1365-2133.1952.tb16160.x. [DOI] [PubMed] [Google Scholar]
  4. Foster K. G., Ginsburg J., Weiner J. S. Role of circulating catecholamines in human eccrine sweat gland control. Clin Sci. 1970 Dec;39(6):823–832. doi: 10.1042/cs0390823. [DOI] [PubMed] [Google Scholar]
  5. HAIMOVICI H. Evidence for adrenergic sweating in man. J Appl Physiol. 1950 Mar;2(9):512–521. doi: 10.1152/jappl.1950.2.9.512. [DOI] [PubMed] [Google Scholar]
  6. HURLEY H. J., Jr, SHELLEY W. B. The role of the myoepithelium of the human apocrine sweat gland. J Invest Dermatol. 1954 Feb;22(2):143–156. doi: 10.1038/jid.1954.19. [DOI] [PubMed] [Google Scholar]
  7. HURLEY H. J., WITKOWSKI J. A. Mechanism of epinephrineinduced eccrine sweating in human skin. J Appl Physiol. 1961 Jul;16:652–654. doi: 10.1152/jappl.1961.16.4.652. [DOI] [PubMed] [Google Scholar]
  8. Prout B. J., Wardell W. M. Sweating and peripheral blood flow in patients with phaeochromocytoma. Clin Sci. 1969 Feb;36(1):109–117. [PubMed] [Google Scholar]
  9. SHELLEY W. B., HURLEY H. J., Jr The physiology of the human axillary apocrine sweat gland. J Invest Dermatol. 1953 Apr;20(4):285–297. doi: 10.1038/jid.1953.35. [DOI] [PubMed] [Google Scholar]
  10. SONNENSCHEIN R. R., KOBRIN H., JANOWITZ H. D., GROSSMAN M. I. Stimulation and inhibition of human sweat glands by intradermal sympathomimetic agents. J Appl Physiol. 1951 Apr;3(10):573–581. doi: 10.1152/jappl.1951.3.10.573. [DOI] [PubMed] [Google Scholar]
  11. SWAN H. J. C. Observations on a central dilator action of adrenaline in man. J Physiol. 1951 Feb;112(3-4):426–437. doi: 10.1113/jphysiol.1951.sp004540. [DOI] [PMC free article] [PubMed] [Google Scholar]

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