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. 2026 Jul 2;6(7):e0006715. doi: 10.1371/journal.pgph.0006715

Beliefs, referrals, and mental healthcare pathways in the Eastern Democratic Republic of Congo

Martial Mumbere Vagheni 1,2,3, Jean-Bosco Kahindo Mbeva 4, Astride Lina Piripiri 5, Joseph Zawadi Kavulivwa 6, Rosemary Ricciardelli 7, Daniel Okitundu Luwa E Andjafono 2, Bives Mutume Nzanzu Vivalya 4,6,*
Editor: Julia Robinson8
PMCID: PMC13327247  PMID: 42391169

Abstract

Although the primary healthcare (PHC) system gatekeeps early access to mental healthcare services, little is known about the factors influencing the use of these services by people with mental disorders living in conflict zones of Eastern Democratic Republic of Congo. The current study describes the patterns and factors associated with pathways to mental healthcare, with an emphasis on how religious beliefs and referral patterns are associated with the use of PHC. We surveyed patients (n = 404) attending nine psychiatric hospitals to elucidate the pathway used for those with mental health needs to obtain care. Binary logistic regressions were performed to identify factors associated with first, second, third, and fourth points of contact when seeking care. In total, 47.3% of patients had their first care contact at a psychiatric hospital while 89.3% were self-referred. Roughly one-third of participants’ first point of contact was a religious leader. Asked about sources of their compromised mental health, 32.7% of respondents reported witchcraft, 30% supernatural powers, and 12.5% divine punishment. Having a family history of mental disorders and a religious affiliation other than being Pentecostal and non-Pentecostal (aOR=0.17, p = 0.026) were associated with lower odds of non-PHC first contact (aOR=0.06, p = 0.004). Additionally, having multiple psychiatric episodes (aOR=9.86, p = 0.028), self-referral (aOR=6.37, p < 0.001), and attributing challenges to divine punishment (aOR=4.68, p = 0.05) or witchcraft (aOR=2.35, p = 0.04) were associated with higher odds of non-PHC first contact. Findings reveal the significant underutilization of PHC for mental health needs in conflict zones, individuals instead favoring self-referral to psychiatric hospitals or religious leaders. This behavior is driven by cultural and religious beliefs, specifically attributing mental disorders to witchcraft, divine punishment, and lack of integrated mental health services within the PHC system. We conclude with discussion of a collaborative model between religious leaders and medical professionals to improve care pathways in conflict zones.

Introduction

In low-income countries (and high-income countries too), many individuals with mental health needs are treated in primary healthcare (PHC) hospitals, which serve as gatekeepers to psychiatric hospitals [1]. The PHC facilities are the first point of contact for those with health needs, because their community health workers and general practitioners provide accessible and comprehensive care, before referring patients in need to specialized settings, like psychiatric hospitals. Efforts to integrate mental healthcare into the PHC system are affected by factors like low mental health prioritization, a shortage of psychotropic medications, and the scarcity of specialists at government hospitals [2].

Cultural myths and religious beliefs also influence how individuals with mental health needs interpret and seek help [3,4], especially from religious leaders and traditional healers [5]. Yet, scholars have not focused on the role of religious beliefs on mental healthcare pathways in conflict-affected regions. An individual’s socio-economic status, belief in the role of supernatural powers in disease etiology [6], and availability of specialized mental healthcare services influence people’s attitudes towards the management of psychiatric disorders [7–10]. These factors negatively affect treatment seeking behaviors, especially in conflict zones, where one in five individuals suffer from at least one mental health disorder [11].

Political conflicts and civil unrest have affected the Eastern region of Democratic Republic of Congo (DRC) for more than two decades. Here, six in ten individuals who attend religious centers for spiritual assistance meet the diagnostic criteria of at least one psychiatric disorder [12]. Seven in ten people attend psychiatric hospitals only after seeking help from traditional healers or religious leaders [5]. While 20% to 50% of the population may have post-traumatic stress disorder (PTSD) or depressive symptoms due to combat exposure [13,14], only a tiny fraction (1.9% to 2.5%) of these cases is recorded or identified within the PHC facilities [12]. In addition, people with mental health needs use several pathways to care, including self-referral [3,10,15]. Barriers to access to mental healthcare services in conflict zones stem from poor integration of mental health in the PHC system to inadequate understanding of the burden of psychiatric disorders. This is particularly the case in jurisdictions of war, poverty, low education, and loss of property. However, contextual factors limiting the use of PHC by individuals with mental health challenges have not yet been deeply assessed in conflict zones.

The Cultural Determinants of the Help Seeking Model (CDHSM) provides an avenue to understand how culture impedes help-seeking behavior for those with compromised mental health. The model includes facilitators and barriers to mental health service provision, such as causal attributions, social significance, context dynamics, and resource availability [4]. We used the CDHSM to frame the current study as it underpins the role of cultural and religious factors in mental health help-seeking behavior. Further, we reflected on the World Health Organization’s Mental Health Gap Action Program [16–18], which is not fully integrated in Eastern DRC. Overall, we aimed to describe the patterns and factors associated with pathways to mental healthcare, with an emphasis on how religious beliefs and referral patterns are associated with the use of PHC.

Method

Study design and setting

We conducted a cross-sectional survey involving patients who attended nine psychiatric hospitals in war torn Eastern DRC between 15th August and 15th December 2021. The selected hospitals included: Polycliniques Sainte Croix of Mulo, Cap Salama, Centre Muyisa, Centre Diaconal Dr. Rohland (Cediar), Bora Uzima, Notre Dame de Lourde, Centre La Guérison, Centre de Relance en Santé Mentale, and Centre pour la Protection des Indigents et de Malades Mentaux (CEPIMA). These facilities met inclusion criteria of: (i) being in a conflict-affected region of North-Kivu, Eastern DRC, (ii) belonging to private managers, and (iii) providing biological and psychosocial therapies to individuals with mental disorders for at least two years and (iv) identified in respective health zones as specialized psychiatric hospitals that receive referral from PHC system. These hospitals have an average bed-capacity of 50. The common mental health disorders of patients in these psychiatric hospitals are substance-use related problems, bipolar affective disorder, schizophrenia spectrum disorders, epilepsy, and major depressive disorder.

Study participants

Participants were patients admitted to psychiatric hospitals, aged between 16 and 65 years, consented to participate by providing an informed written consent or assent, and met the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-V) criteria for substance use disorder, bipolar affective disorder, schizophrenia spectrum disorders, major depressive disorder, and posttraumatic stress disorder. Exclusion criteria were patients with cognitive impairment who would impair their ability to comprehend the consent form and the questionnaire. The sample size of 404 participants was determined using the modified Daniel’s formula for cross-sectional studies [19] with a population proportion of 50%, the 95% confidence level, and 5% margin of error. Participants with missing responses were excluded from the analysis, except for the question about religious beliefs and referral patterns, where five respondents did not answer. No data imputation was performed. The heterogenic distribution of the sample across the nine hospitals is presented in (S1 Table).

Data collection, instruments, and variables

With the permission of the executive directors, we reviewed the medical records of potential participants on arrival, then obtained psychiatric diagnoses. We utilized consecutive sampling techniques during the recruitment process going from 15th of August to 15th of December in 2021. Trained research assistants used Kobo Collect to administer a structured survey to eligible patients who provided written informed consent or assent. A structured questionnaire, developed for this study, was piloted among 40 participants and revised based on pilot data feedback. The questionnaire was translated from French to Kiswahili by two professional translators with a mental health background. To maintain inter-rater reliability and data quality, all research assistants received standardized training on survey administration, ethical conduct, and use of the digital data collection tool. Field supervision was conducted throughout data collection. Here, we conducted periodic joint interviews, and daily consistency checks of uploaded forms to identify and resolve discrepancies in real time.

We administered face-to-face surveys in person, each 45 and 60 minutes in duration. Collected socio-demographic information included age, sex, marital status, level of education, occupation, and religion. Clinical data included information about patterns of admissions: place (i.e., referral hospital), mode of admission (referred versus self-referred), type (new admissions and readmissions) and number of admissions. We also collected information on the age of onset of psychiatric symptoms, evolution of the psychiatric diagnosis starting from the first episode of presentation, recurrent acute episodes, progressive disease or unknown evolution mode; and family history of mental disorders.

Regarding religious orientation, we collected information by asking: “What is your religion?” with answer options of “I am Catholic, Protestant, Adventist, Muslim, or other”. We then asked about religiosity: ‘How would you categorize yourself as religious? Religiosity was categorized based on the frequency of attendance at religious services, an approach commonly applied in major international surveys [20,21], and responses from pilot testing. In line with these instruments, we defined three levels: very religious (more than once per week), moderately religious (weekly to a few times per month), and indifferent (less than once per month or never). We also assessed how participants interpreted their mental health challenges, asking: “In your opinion, what is the cause of the mental disorder?” with answer options of “natural disease, Divine punishment, witchcraft, other mentioned causes, and unknown causes.”

We refer to care pathways as the avenue pursued by any individual with compromised mental health to reach the appropriate mental health treatment center [9]. To measure pathways to mental healthcare, we used an adapted version of the collaborative World Health Organization’s “Pathway Study” encounter form. The form outlines care-seeking behaviors and treatment pathways known to be used by individuals with mental health challenges before they seek healthcare in psychiatric hospitals [15]. The WHO encounter form is 22 item semi-structured questionnaire that records the patient’s “pathway contacts” referring to who the patient initially sought treatment from, followed by second, third, etc. treatment sought, while including information on delays, and referral sources. Traditional healers and faith healers are examples of informal providers of treatment used in low- and middle-income countries to map help-seeking behavior, identify delays in receiving care, and compare healers to professional health facilities. In certain contexts (like Ethiopia), the pathway has been characterized as both a possible and acceptable method for gathering pertinent pathway data [22]. The mental health care referral pathway was assessed by recording the sequence of providers consulted by each participant before reaching psychiatric services. Participants were asked to identify their first, second, third, and fourth or subsequent point of contact for mental health care. For each step, the type of provider consulted was categorized as community health worker, religious leader, traditional healer, primary health care facility, psychiatric hospital, or any other unidentified provider. Then, we grouped participants in two categories for each contact point: PHC workers (i.e., community health workers, and medical professionals in health centers and general hospital), and all other stakeholders (i.e., psychiatric nurses, clinical psychologists, religious leaders, traditional healers, and unidentified actors) as non-PHC workers.

Data processing and analysis plan

Statistical analyses were performed using the R Studio Integrated Development Environment Version R 4.2.2. Using the (S1 Data), we summarized descriptive statistics as absolute frequencies and percentages for categorical variables, means, and standard deviations or medians and interquartile ranges for continuous variables. Comparisons between demographic and clinical factors were examined using a chi-squared test for categorical variables (regarding the different points of contact for care). We conducted separate binary logistic regression analyses for each stage of care-seeking (first, second, third, and fourth point of contact) to identify factors associated with the use of non-primary healthcare (non-PHC) services versus PHC service at each stage. For each model, the dependent variable was coded as 1 = non-PHC contact (e.g., religious leaders, traditional healers, psychiatric hospitals) and 0 = PHC contact. Analyses at each stage were restricted to participants who had reached that stage in their care pathway (404 participants at the first contact, 308 for the second, 179 for the third and 104 for the fourth or more contact). Because participants were recruited from multiple psychiatric hospitals, cluster-robust standard errors at the hospital level were used to account for within-hospital correlation. Predictor variables included sociodemographic characteristics (age, sex, marital status, employment), cultural and belief-related factors (religious affiliation, religious involvement, causal attribution), and clinical characteristics (admission mode, illness severity, recurrence, and family history of mental disorders) based on existing studies [23–25]. Factors associated with the outcome at p < 0.20 in bivariate analyses were entered into multivariate models. Adjusted odds ratios (aOR) with 95% confidence intervals were reported, and statistical significance was set at p < 0.05. These models were estimated separately for each contact stage because determinants of initial help-seeking may differ from factors influencing subsequent care decisions.

Ethical considerations and reporting guidelines

Ethical approval was provided by the Ethics committee of North-Kivu (No. 005/TEN/CENK/2020), and the study was carried out in accordance with the Helsinki declaration. Participants were anonymous, participation was voluntary, and there were no rewards for participating. All participants provided their tacit written consent or assent. We also obtained consent from parents or guardians of the minors included in this study. The manuscript was prepared in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) checklist for cross-sectional studies [26].

Results

Sociodemographic and clinical characteristics of study participants

Most participants were aged between 18 and 50 (72.3%), men (59.4%), single (63.5%), Christian (71.8%), with moderate religious involvement (55.4%). Among patients presenting to psychiatric hospitals, 359/402 (89.2%) reported self-referral, and 204/400 (51%) attended the psychiatric hospital for follow-up or medication refills. The mean age of the first episode for psychiatric symptoms was 27.54 ± 12.43. Furthermore, 32% of participants attributed the cause of their mental health disorders to witchcraft, 30% to supernatural power, 12.5% to divine punishment. The first acute episode was reported at 30.5%; indicating the proportion of the sample who experienced a non-first episode of 69.6%. All characteristics of study participants are presented in Table 1.

Table 1. Baseline characteristics of study participants.

Characteristic Statistic
Frequency Percentage
Age Mean: 31.02, SD: 5.14, Min: 16, Max: 65
< 18 47 11.6
18-50 292 72.3
51- 65 65 16.1
Sex
Male 240 59.4
Female 164 40.6
Marital status
Married/cohabiting 106 26.2
Single 258 63.9
Divorced 27 6.7
Widower 13 3.2
Occupation
Public 35 8.6
Private 220 54.5
Unemployed 149 36.9
Educational level
University 26 6.4
Secondary 172 42.6
Primary 172 42.6
No formal education 34 8.4
Religious orientation
Non-Pentecostal 318 78.8
Pentecostal 37 9.2
Other 41 10.2
None 8 2
Religious attitude (N = 399)
Very religious 122 30.3
moderate 221 54.7
indifferent 56 14
Mode of admission (N = 399)
Self-referred 365 89.2
Referred 34 10.8
Age of first episode of psychiatric symptoms (years) (N = 404)
  ≤ 15 33 8
 16–25 127 31.4
 26–40 84 20.8
≥ 41 45 11.1
 Unknown 115 28.5
Evolutionary profile (N = 404)
 First acute episode 123 30.4
 Recurrent acute episodes 138 34.2
 Progressive disease 117 29
  Mixed 26 6.4
Family history of mental disorders (N = 404)
 None 189 46.8
 Episodic disorder 156 38.6
 Chronic disorder 33 8.2
 Other 26 6.4
Causal attribution (N = 404)
 Natural 121 29.4
 Divine punishment 50 12.9
 Witchcraft 132 32.7
 Other 16 4
 unknown 85 21
Attending the hospital for follow-up or medication refills (N = 400)
 Yes 204 51
 No 196 49

*N: number of participants and the denominator for percentages

Determinants of first, second, third and fourth point for mental health seeking care

Of participants whose first contact was a hospital (n = 404), nearly 1/3 (n = 121) reported subsequently consulting a religious leader. Psychiatric hospitals remained the most used facility for all contacts, followed by religious leaders. The self-reported sequences were subject, of not, to recall errors and, thus, do not establish knowledge of treatment effectiveness. In addition, 74% and 87.5% of participants attended psychiatric hospitals as their second and fourth care seeking options, respectively (see Figs 1–4).

Fig 1. Distribution of participants by type of first contact for mental health care (n = 404).

Fig 1

Fig 4. Distribution of participants by type of fourth contact for mental health care (n = 104).

Fig 4

Fig 2. Distribution of participants by type of second contact for mental health care (n = 308).

Fig 2

Fig 3. Distribution of participants by type of third contact for mental health care (n = 179).

Fig 3

Stage specific predictors of seeking mental health services in non-primary health care facilities

Multivariate analyses revealed how attributing challenges to divine punishment was associated with higher odds of non-PHC first contact (aOR = 4.68, 95% CI [1.24–30.71] p = 0.040). A similar association was observed for witchcraft attributions (aOR = 2.35, 95% CI [1.06–5.45]. p = 0.040) and self-referral (aOR=6.37, 95%CI [2.82-14.59], p < 0.001). Self-referral was also associated with increased odds of seeking care in non-PHC settings on the second (aor = 3.25, 95%CI [1.08-8.85], p = 0.026) and third points of contact (aOR=9.57, 95% CI [2.00-51.49], p = 0.005). Patients with multiple episodes of psychiatric symptoms (aOR = 9.86, 95% CI [1.35-86.82], p = 0.028) had a higher likelihood of seeking mental healthcare in the non-PHC system at the third point of contact. Given the wide CI and multiple comparisons, this estimate is imprecise and should be interpreted cautiously. Having religious affiliation other than Pentecostal and non-Pentecostal (aOR=0.17, 95% CI [0.03-0.97], p = 0.026) and having a family history of mental disorders (aOR=0.06, 95%CI [0.01-0.39], p = 0.004) were associated with a decreased likelihood of seeking mental health care in non-PHC system. (see Table 2).

Table 2. Stage-specific predictors of seeking care in non-PHC versus PHC setting across the first, second, third and fourth or subsequent contacts.

First contact for mental health Second contact for mental health third contact for mental health fourth contact for mental health
PHC NPHC PHC NPHC PHC NPHC PHC NPHC
n % n % aOR 95% CI [x–y] P n % n % aOR 95% CI [x–y] P n % n % aOR 95% CI [x–y] p n % n % aOR 95% CI [x–y] p
Religion
Non-Pentecostal 40 12.6 278 87.4 Ref 15 6.2 226 93.8 Ref – 14 10 126 90 Ref 5 6.7 70 93.3 Ref
Pentecostal 8 21.6 29 78.4 0.52 [0.09-3.04] 0.5 1 3.1 31 96.9 1.99 [0.75-5.27] 0.17 3 15 17 85 2.24 [0.32-20.68] 0.48 0 0 13 100 0.98 [0.46-2.08] 0.96
Other 8 19.5 33 80.5 2.01 [0.87-4.65] 0.1 4 13.8 25 86.2 2.57 [0.95-7.00] 0.06 5 31.3 11 68.6 0.17 [0.03-0.97] 0.04 1 7.1 13 92.9 0.24 [0.15-0.74] 0.11
None 1 12.5 7 87.5 1.46 [0.23-9.29] 0.7 0 0 6 100 4.83 [0.99-11.18] 0.1 0 0 3 100 0.63 [0.29-1.36] 0.24 0 0 2 100 0.42 [0.20-0.88] 0.22
Religious attitude
Very religious 24 19.8 98 80.3 Ref – 5 4.6 104 95.4 Ref – 7 11.7 53 88.3 Ref 3 8.1 34 91.9 Ref
moderate 25 11.3 196 88.7 1.58 [0.79 - 3.14] 0.2 12 7.7 143 92.3 67.47 [18.55-245.37] 0.06 12 13.6 76 86.4 NS 3 6.1 46 93.9 3.61 [1.08-12.07] 0.04
indifferent 8 14.3 48 85.7 0.91 [0.34 - 2.57] 0.8 3 7.5 37 92.5 0.18 [0.03-1.21] 0.08 3 10.3 26 89.7 NS 0 0 17 100 1.14 [0.36-3.58] 0.83
Address –
Health zone 32 11.9 237 88.1 Ref 12 6 188 94 Ref – 14 11.7 106 88.3 Ref 3 4.4 65 95.6 Ref
Other health zone 24 18.5 106 81.5 0.78 [0.40 - 1.52) 0.4 8 7.7 96 92.3 0.85 [0.44-1.66] 0.64 8 14 49 86 3 8.8 31 91.2 2.54 [0.67-9.58] 0.17
Admission mode
referred 18 41.9 318 58.1 Ref 6 15.8 254 84.2 Ref – 14 38.9 145 61.1 Ref 2 15.4 11 84.6 Ref
self-referred 38 10.7 25 89.3 6.37 [2.82 -14.59] <0.001 14 5.2 32 94.8 3.25 [1.08 - 8.85] 0.03 7 8.8 11 91.2 9.57 [2.00-51.49] 0.01 4 4.4 86 95.6 0.60 (0.96-3.70] 0.58
Development of the disease
First acute episode 21 17.1 102 82.9 Ref 5 7.6 61 92.4 Ref – 5 19.2 21 80.8 Ref 2 12.5 14 87.5 Ref
recurrent acute episodes 21 15.2 117 84.8 0.48 [0.19-1.18] 0.1 7 5.2 128 94.8 0.38 [0.11-1.31] 0.13 4 4.3 89 95.7 9.86 [1.35-86.82] 0.03 1 2 49 98 0.89 [0.16-4.99] 0.89
progressive disease 13 11.1 104 88.9 1.32 [0.53-3.30] 0.6 8 9.1 80 90.9 0.75 [0.20-2.86] 0.67 12 23.5 39 76.5 0.86 [0.16-4.44] 0.91 3 9.4 29 90.6 6.35 [2.07-19.53] 0.6
Mixed 2 7.7 24 92.3 1.40 [0.62-3.12] 0.4 0 0 19 100 0.49 [0.09-2.72] 0.42 1 11.1 8 88.9 2.20 [0.21-53.88] 0.54 0 0 6 100 4.77 [1.55-14.70] 0.07
Family history of mental health illness
None 28 14.8 161 85.2 Ref – 6 4.4 132 95.7 Ref – 8 11.6 61 88.4 Ref 3 7.7 36 92.3 Ref
episodic disorder 23 14.7 133 85.3 0.24 [0.14-1.41] 0.5 11 8.9 113 91.1 0.47 [0.16 - 1.28] 0.21 6 7.5 74 92.5 1.37 [0.27-7.66] 0.71 3 6.3 45 93.8 2.45 [0.43-14.22] 0.32
chronic course 5 15.2 28 84.9 0.74 [0.42-1.30] 0.3 3 11.1 24 88.9 0.36 [0.09 - 1.83] 0.08 7 38.9 11 61.1 0.06 [0.01-0.39] 0.004 0 0 13 100 9.99 [1.24-65.13] 0.13
Other 1 3.9 25 96.2 0.77 [0.43-1.38] 0.4 0 0 19 100 NS 1 8.3 11 91.7 1.12 [0.12-28.47] 0.93 0 0 4 100 1.47 [0.04-6054] 0.8
Causal attribution
Natural 23 19 98 80.5 Ref 4 4.7 82 95.4 Ref – 3 6.7 42 93.3 Ref 1 3.9 25 96.2 Ref
Divine punishment 3 6 47 94 4.68 [1.24-30.71] 0.04 1 2.9 33 97.1 6.79 [3.00-15.40] 0.69 1 4.6 21 95.5 4.3 [0.33-128.67] 0.33 0 0 10 100 4.13 [0.50-34.02] 0.19
Sorcery 16 12.1 116 87.9 2.35 [1.06-5.45] 0.04 10 9.2 99 90.8 1.67 [0.78-3.57] 0.63 8 12.1 58 87.9 1.32 [0.20-8.29] 0.84 3 7.7 36 92.3 5.88 [0.89-38.91] 0.07
other 2 12.5 14 87.5 1.48 [0.35-10.22] 0.1 0 0 11 100 NS – 1 16.7 5 83.3 0.89 [0.05-32.65] 0.9 0 0 3 100 6.16 [0.19-17.64] 0.13
unknown 13 15.3 72 84.7 1.21 [0.53-2.83] 0.7 5 7.4 63 92.7 3.85 [1.80-8.22] 0.3 9 22.5 31 77.5 0.26 [0.04-1.35] 0.12 2 7.7 24 92.3 0.56 [0.01-23.93] 0.76

aOR: adjusted odd ratio; PHC: primary health care; NPHC: non-primary health care; p: p value; CI: confidence interval; Outcome coded as 1 = non-PHC and 0 = PHC at each contact stage; aOR>1 indicates higher odds of seeking care in non-PHC settings; aOR<1 indicates decreased likelihood of seeking mental health care in non-PHC settings.

Discussion

In the current study, we sought to describe the patterns and factors associated with pathways to mental healthcare, with an emphasis on how religious beliefs and referral patterns are associated with the use of PHC in war-torn Eastern DRC where mental health services are not fully integrated in the PHC system. We found that most participants presenting to psychiatric hospitals were self-referred, which aligns with findings from previous research in similar (i.e. conflict zone) settings [27,28]. Determinants of self-referral to psychiatric hospitals included the accessibility of the hospitals, the availability of trained mental health specialists, and a well-established referral system linking the PHC and psychiatric hospitals [29,30].

Access to psychiatric hospitals in low-income countries is impaired by socio-economic status, cultural norms, and religious beliefs. Specifically, we found that one in four or 25 percent of participants presenting at PHC facilities have a mental health challenge [31]. In our cohort, the results indicate that eight to ten people with mental health disorders attended psychiatric hospitals after seeking help from traditional healers and religious leaders, echoes the findings of studies conducted by Nakku and colleagues [32] and Eagle et al [33]. Moreover, the high rate of non-first episode of 69.6% in our sample could result of patients abandoning medical treatment in favor of religious centers during periods of remission. In Eastern DRC, religious beliefs and cultural norms influence health-seeking behaviors, as highlighted by our previous study showing that nearly six in ten people seeking spiritual help in religious centers had psychiatric symptoms [5], regardless of them ever being admitted or not. This is, further, supported by the proportion of patients admitted to psychiatric hospitals who returned to religious centers for their second contact. In DRC, like in several Sub-Sahara African countries, patients with mental health challenges usually spend months or years navigating religious or traditional pathways or PHC facilities. These individuals only reach psychiatric hospitals once their condition has become chronic and severe, with impaired quality of life and complications such as suicide attempts. Their behavior is better explained by high proportion of non- Pentecostal participants in our sample, which aligns with Eagle et all’s work that emphasized how both Pentecostal/Charismatic and non-Charismatic Protestant pastors in Eastern DRC endorsed a combined approach to treating symptoms of depression, which supports the prevalence of both spiritual and medical interventions [33].

Several factors influence citizens’ decisions to seek treatment for mental health disorders, including severity of illness, suitability of treatment, and sociocultural practice and religious denomination. Approximately one-third of participants indicated they had initially consulted a religious leader as their first point of contact, after which a notable proportion (14.29%) continued to seek additional support from a religious leader (i.e., second contact), with fewer presenting to religious leader at third and fourth. This could explain the high proportion of the sample experiencing a non-first episode in this cohort because of patients abandoning medical treatment in favor of religious leaders during periods of remission. The finding suggests religious leaders can serve as effective partners in facilitating access to formal mental health care, given they may practice traditional medicines and, most importantly, provide an alternative to psychiatric treatment in countries with few mental health specialists [5,12]. Moreover, our findings reveal, after first contact in seeking mental health care in psychiatric hospitals, a notable proportion of participants sought additional support from religious leaders and traditional healers at the second contact, with fewer doing so at the third and fourth contacts. Religious leaders and traditional healers are of paramount roles in the management of mental health challenges even when psychiatric treatment is used by individuals with mental health challenges in psychiatric hospitals [34].

Understanding interpretations of mental health needs influences help seeking behaviors. Thus, for example, scholarship has found attributing mental health disorders to divine punishment and witchcraft encourages trust in the therapeutic effect of spirituality and religion, and the rejection of pharmaceutical interventions for mental health disorders [35]. Aligning with existing literature [30,36,37], we too found believing that compromised mental health results from supernatural forces, such as divine punishment or witchcraft, appears associated with reliance on PHC systems, especially in the first point of care, in addition to self-referrals. Stigma, religious beliefs and practices, and a lack of accurate information about mental health challenges influence how people interpret mental health problems and if they seek care from a religious leader [38], thus shaping how individuals perceive and seek help for mental health in low-income and low-resource settings [39]. Existing evidence emphasizes how having unskilled medical professionals in PHC and psychiatric hospitals exacerbate the influence of cultural determinants of health for those in dire need of intervention, thus constituting a major contributing factor for the poor utilization of mental health services, particularly in low-income countries [39,40]. Addressing stigmas using culturally appropriate mental health education and establishing a living interaction between medical professionals, traditional healers and religious leaders may, in consequence, promote earlier contact with appropriate mental healthcare services. Due to their role in care pathways, policymakers should consider establishing evidence-informed interventions that target the provision of biopsychosocial therapies associated with spiritual care for people seeking help in primary health care settings [41].

Late entry to psychiatric care and need of collaborative model between religious leaders and medical professionals

Our findings show how the current medical system in the DRC, the PHC system, is too often bypassed because the model does not fully account for the cultural determinants of health, especially for those with metal health needs. A significant proportion of individuals seeking religion informed interventions prior to and after seeking care in psychiatric hospitals reveals a need for collaborative care provision from religious and medical leaders. Thus, a holistic model of care that considers religious and cultural determinants of health, combining spiritual, traditional, and biomedical treatment approaches, is necessary for the betterment of and appropriate management of mental health challenges among individuals in conflict zones of DRC. Such a collaboration constitutes an evidence-informed strategy which could be both accessible and feasible, thus promising, for DRC. The Emerald consortium, involving six countries (Ethiopia, India, Nepal, Nigeria, South Africa, and Uganda) demonstrates how strengthening policy, legislation, and health system capacity can, if the cultural importance of religious leaders and traditional healers is considered, enable the integration of mental health into primary care [42]. In Northern Ghana too, efforts to integrate traditional healers and biomedical providers show how trust-building, clear recognition of healers, and structured communication mechanisms help overcome barriers to collaboration [43]. Additionally, global evidence from recent collaborative models indicates that involving traditional healers in training and formal referral networks improves mental health outcomes and increases link to psychiatric services [44]. Drawing on these examples, establishing standardized communication channels between medical professionals and religious leaders, while strengthening the capacity of PHC workers, is a realistic and context-appropriate step toward reducing reliance on religious and traditional healing centers among people with mental health needs. Finally, good mental health is a universal right, and additional efforts are needed to support individuals suffering from mental health disorders, particularly those living with the added burdens of war and civil unrest.

Study limitations

The sample consists only of psychiatric hospital patients, excluding individuals within communities outside of such, which reduces the voices of those who did not receive care from psychiatric facilities. Additionally, the study being cross-sectional study, rather than longitudinal, does not enable the establishment of a cause-effect relationship. Generalizability too is hindered by the non-randomized sampling method and the lack of controls in the analysis. In response, longitudinal studies and qualitative work nuancing context are warranted, particularly if inclusive of people living in communities, primary health care providers, and individuals’ experiences with and interpretations of psychiatric hospitals. This is necessary given our participants were exclusively patients attending psychiatric hospitals regardless of the number of admissions or episodes. Further limitations include how participants pathway-to-care histories were based solely on self-report, susceptible to recall and social desirability biases, as well as potential misclassification regarding service provision attempts and processes, particularly when help-seeking trajectories are intricate and involve numerous care contacts. Our study relied on pretested self-reported questionnaires because of a lack of validated scales detailing religious involvement. Further studies should aim to validate these tools for the individuals living in conflict zones such as the Eastern DRC. The number of predictors included in the multivariate models may have been large relative to the number of outcome events at some contacts stage, such as attributing challenges to divine punishment was associated with higher odds of non-PHC first contact with broad confidence ranges. This may have resulted in overfitting, unstable parameter estimates, and wide confidence intervals, thereby reducing the precision of some adjusted odds ratios. In particular, the broad confidence intervals observed for some predictors suggest limited statistical power and possible sparse-data bias. Therefore, associations identified in later-stage models should be interpreted cautiously. In addition, standard model diagnostics such as goodness-of-fit statistics, pseudo-R², and formal checks for multicollinearity between predictors were not conducted, which may further limit the robustness of our findings. Because separate logistic regression models were fitted for each contact stage, the analysis did not explicitly account for within-person correlations across repeated contacts over the care pathway. Therefore, the results should be interpreted as snapshots at each stage rather than as longitudinal patterns. Despite this, the method offers valuable insights into how care-seeking behaviors evolve across different points in the care pathway. Future studies with larger sample sizes and more rigorous model diagnostics are warranted to confirm these associations, perhaps a mixed-effects model could be used in future analyses. Sociodemographic variables such as age, sex, marital status, and employment status were examined but showed no significant association with the four points of contact in bivariate analysis, and education was excluded during stepwise logistic regression, which warrants additional research intended to reveal why. Nevertheless, the absence of these socioeconomic indicators in the final models may still limit interpretation, as they are known from other settings to influence pathways to care. Furthermore, the width of the confidence intervals does require caution as it suggests a sufficient sample size is lacking, which could affect the estimated correlations analyzed through the regression models.

Conclusion

Our findings reveal a significant underutilization of PHC for mental health needs in conflict zones, attributable, at least in part, to a failing adequately accounting for the cultural determinants of mental health. Instead, patients favored self-referral to psychiatric hospitals or religious leaders due to their strong cultural and religious beliefs (i.e., attributing mental health disorders to witchcraft, supernatural powers, or divine punishment), as well as a lack of integrated mental health services within the PHC system in conflict zones of DRC. While the DRC’s situation is extreme due to war and civil unrest, there remains an undeniable need for a collaborative model between religious leaders and medical professionals intended to improve care pathways in these conflict zones. Thus, much can be learned from drawing on models that have been successfully used with positive outcomes elsewhere. Finally, building the capacity of frontline workers, improving referral links, and promoting culturally sensitive education could help make mental health care more accessible and responsive in fragile settings.

Supporting information

S1 Table. Distribution of study participants per psychiatric hospital.

(DOCX)

pgph.0006715.s001.docx (17.2KB, docx)
S1 Data. Dataset.

(XLSX)

pgph.0006715.s002.xlsx (51.1KB, xlsx)

Acknowledgments

Authors would like to acknowledge the study participants for their time they committed to be part of this study and the research assistants who collected the data.

Data Availability

The dataset used to support the findings of this study are available from the corresponding author and have been deposed in a public repository (Supporting information).

Funding Statement

This study did not receive any funding. The financial support was provided by the authors, and they had no role in study design, data collection, analysis, or interpretation of data, as well as the submission for publication.

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PLOS Glob Public Health. doi: 10.1371/journal.pgph.0006715.r001

Decision Letter 0

Collins Asweto

2 Sep 2025

PGPH-D-25-01441

Entry Points to Mental Healthcare: The Influence of Beliefs and Referrals on the Use of the Primary Healthcare System in North Kivu Province, Eastern Democratic Republic of Congo

PLOS Global Public Health

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Reviewer #1: Thank you for submitting this manuscript, makes significant contribution in exploring mental healthcare pathways in a conflict-affected region, addressing an important research gap with original data from a challenging context. While the study is methodologically sound and offers valuable insights, several aspects—particularly clarity of language, structure, and adherence to reporting and data-sharing standards—require improvement. Here below are issues that need to be addressed: Summary of Key Issues

Data Availability: Per PLOS policy, deposit anonymized data in a public repository or provide a valid reason for exemption.

Section-by-Section Feedback

A. Title &

1. Consider shortening the title for clarity, e.g., ‘Beliefs, Referrals, and Mental Healthcare Pathways in Eastern DRC’ to make it more concise while retaining the main elements.

B. Abstract Paragraph 1 (lines 27–49)

2. Issue: The abstract is lengthy with some redundancy (e.g., repeating “psychiatric hospital” multiple times).

Suggestion: remove redundancy, streamline background; focus on key statistics, main predictors, and implications. Include important statistical results (aORs, p-values) for stronger impact. Ensure all abbreviations (e.g., PHC) are defined on first use.

C. Introduction(lines 52–57)

3. Correct grammar in paragraph 1 (“play” → “plays”), and ensure consistent tense usage.

4. Shorten long sentences in paragraph 3 for better readability.

5. End the introduction with a one-sentence, clearly stated research objective/hypothesis.

6. lines 66–77

Issue: Long sentences with multiple clauses reduce clarity.

Suggestion: Break into shorter sentences for readability.

7. Lines 96–102

Issue: Study aim is stated but not as a clear, concise research objective.

Suggestion: End the Introduction with a specific, one-sentence statement of objectives or hypothesis.

D. Methods

6. Rewrite hospital inclusion description for clarity (paragraph 2).

7. Simplify questionnaire description (paragraph 4).

8. Justify or cite categorization of religiosity (paragraph 6).

9. Specify all variables used in regression and cite literature for selection (paragraph 9).

10.

8. Lines 105–118; Study Setting

Issue: Minor grammar and clarity issues (“resulting in Polycliniques…” is awkward).

Suggestion: Rewrite for clarity, e.g., ‘The selected hospitals included… These facilities met inclusion criteria of…’.

9. lines 131–143; Data Collection

Issue: Phrase ‘never been published’ in describing questionnaire is redundant.

Suggestion: Simply state ‘a structured questionnaire developed for this study.’

10. lines 153–158; Religiosity Measures

Issue: Definition of ‘very religious’ as ‘more than five days a week’ may need referencing or justification.

Suggestion: Cite supporting literature for these cut-offs or note they were based on pilot testing.

11. lines 172–182; Statistical Analyses

Issue: Variables included in regression are said to be ‘chosen based on existing studies’ without listing them fully.

Suggestion: Specify variables and cite relevant studies for transparency.

E. Results

12. lines 194–199; Clinical Characteristics

Issue: Reported relapse rate (69.5%) is important but not discussed in results narrative.

Suggestion: Briefly contextualize its significance in the results section.

13. Tables 2–4

Issue: Inconsistent p-value and CI formatting across tables/figures.

Suggestion: Standardize format per PLOS style (e.g., p=0.05, 95% CI [x–y]) in all tables.

F. Discussion

14. lines 229–237

Issue: Repeats content from abstract nearly verbatim.

Suggestion: Focus on interpreting findings rather than restating them.

15. lines 268–277); Integration Recommendation

Issue: Long sentence chains make the recommendation difficult to follow.

Suggestion: Split into separate sentences: one for holistic model advocacy, one for integration, one for collaboration mechanisms.

16. Lines 278–291; Policy Implications

Issue: Important points on stigma and cultural beliefs, but needs references to back claims (e.g., ‘health workers… do not have adequate training’).

Suggestion: Add citations or state that this is based on study findings.

G. Limitations

17. Lines 292–305

Issue: ‘Quantitative approached’ correct ‘approach’ to ‘approach’, clarify whether 404 is truly low sample size for cross-sectional design

Suggestion: Revise wording to reflect actual limitation and avoid misleading reader.

H. Conclusion

18. Lines 306–312

Issue: Restates results without linking back to broader literature or practical implications in depth.

Suggestion: End with a strong recommendation for policy/practice based on findings, i.e. Strengthen conclusion with specific, actionable recommendations.

I. Other general Points.

19. Language: Throughout, minor grammar and syntax issues need correction (subject–verb agreement, tense consistency). Recommend professional English editing.

20. Reporting Guidelines: Add explicit statement in Methods noting adherence to STROBE checklist for cross-sectional studies.

21. Data Availability: PLOS encourages depositing anonymized data in a public repository rather than ‘available on request.’

22. Reference List: Check for over-reliance on the authors’ own work and ensure balanced citation of independent studies.

Reviewer #2: Reviewer Report

Manuscript title: Entry Points to Mental Healthcare: The Influence of Beliefs and Referrals on the Use of the Primary Healthcare System in North Kivu Province, Eastern Democratic Republic of Congo

Manuscript number: PGPH-D-25-01441

Article Type: Research Article

Overall Assessment

This manuscript addresses an important and under-researched topic—pathways to mental health care in conflict-affected settings—using data from psychiatric hospitals in Eastern DRC. The focus on religious beliefs, self-referral patterns, and primary healthcare underutilization is relevant for health systems research and aligns with PLOS Global Public Health’s scope.

However, the paper has substantial weaknesses in writing clarity, methodological rigor, result presentation, and interpretation of findings. There are contradictions between reported numbers, unclear definitions of key terms, insufficient statistical detail, and overgeneralized conclusions that are not fully supported by the study design. The limitations section underplays key biases, and the recommendations are broad without a clear evidence-based implementation framework.

In its current form, the manuscript requires major revision before it can be considered for publication.

Major Comments

1. Writing Clarity and Structure

The manuscript contains multiple grammatical errors, awkward phrasing, and inconsistent terminology (e.g., “war-tone” vs “war-torn”; “non-conventional hospitals” vs “non-primary healthcare hospitals” vs “psychiatric hospitals”).

Many sentences are overly long and repetitive, reducing clarity for an international audience. The Abstract and Discussion in particular repeat the same statistics without adding new interpretation.

Clearer definitions are needed for “non-conventional hospital,” “primary healthcare hospital,” and “psychiatric hospital” early in the Methods to avoid confusion.

2. Contradictions in Findings

Self-referral was reported as 89.2% (Results) and also described as 47.3% first contact with psychiatric hospitals (Figure 1), which appears inconsistent. Authors should reconcile or explain this discrepancy.

In the Discussion, “one in three” patients seeking religious care after hospital treatment is highlighted as a major finding, but this pattern is not clearly supported by the presented data tables.

The proportion attributing illness to “God’s punishment” (12.85%) is comparatively small, yet it is discussed as a dominant explanatory factor without proportional emphasis on witchcraft (32.67%) or natural punishment (29.95%).

3. Methodological Rigor

Sampling bias – The sample consists only of psychiatric hospital patients, excluding individuals who never access these facilities. This likely overestimates the proportion of non-primary healthcare pathways.

Instrument validation – The survey tool was self-developed; while piloted, no psychometric properties (e.g., reliability coefficients, validity evidence) are provided.

Recall bias – Pathway-to-care histories rely entirely on self-report, which is particularly vulnerable to recall error in multi-contact health-seeking patterns. This is not discussed as a limitation.

Variable selection for regression – Factors “chosen based on existing studies” is too vague. Authors should specify model-building strategy and justify inclusion/exclusion.

4. Results Reporting

Inconsistent sample sizes: Table 2 reports n=411, but Methods specifies n=404.

Regression results have extremely wide confidence intervals (e.g., aOR=9.86, CI=1.35–86.82), indicating unstable estimates likely due to small subgroup counts—yet no cautionary interpretation is provided.

Missing model diagnostics (goodness-of-fit, pseudo-R²) and no check for multicollinearity between predictors.

Figure 1 lacks axis labels, clear legends, and an explanation of what “n” values represent at each stage.

5. Interpretation and Overgeneralization

The authors make causal-sounding claims (e.g., “beliefs increase the odds”) from cross-sectional association data without sufficient caution.

Recommendations to integrate religious leaders into formal care systems are not directly supported by intervention evidence from this study.

Conclusions generalize to “most patients with mental disorders in war-torn zones” despite only sampling those attending psychiatric hospitals.

6. Limitations

Important biases—recall bias, social desirability bias, and misclassification—are missing from the limitations section.

No discussion on the absence of socioeconomic variables (income, education) in regression models, despite their likely influence.

Missing data handling is not described.

Minor Comments

Abstract: Clarify the meaning of “non-conventional hospitals” and ensure percentages match those in Results.

Introduction: The review of literature is relevant but would benefit from more DRC-specific policy context (e.g., mhGAP integration efforts).

Methods: Specify how missing values were addressed and whether any data imputation was performed.

Tables: Include denominators for percentages and ensure all abbreviations (PHC, aOR) are defined in footnotes.

Discussion: Reduce repetition of numerical results already presented; focus on interpreting unexpected or contextually important findings.

Language: Correct typographical errors (“necessarily modifications” → “necessary modifications”, “tone” → “torn”).

References: Ensure consistent formatting according to PLOS style (some references are missing full journal details).

Recommendation

Major Revision – While the topic is important and the dataset potentially valuable, substantial rewriting, methodological clarification, and data reporting improvements are needed before the manuscript can be considered for acceptance.

Reviewer #3: Authors have chosen a legible topic that needs to get a high appreciatory. Introductory section may be further developed to add some more relevant literature. Implications of the study may galvanize other readers to follow same type of study.

Reviewer #4: Overall: Several sentences exceed 30 words; shortening would improve clarity. Consistent tense usage (past for methods/results, present for implications) should be ensured.

Abstract: Well-structured, but some sentences are long and could be more concise.

L28–31: Combine to avoid redundancy in stating the knowledge gap.

L34: “patients who attending” → “patients attending.”

L46–47: “due to such determinant” → “due to determinants such as.”

Introduction

L52: “Although primary health care play” → “plays.”

Good framing of cultural and systemic barriers; relevant literature cited.

L63–65: Sentence structure awkward; revise for clarity (“have not centered on people in war-torn settings or on patterns…”).

L78–81: Strong justification with prevalence data.

L87–94: Clear explanation of theoretical framework; well-linked to study aim.

L97–101: Slight grammatical issues; tighten for clarity. For example, “aimed to the patterns” → “aimed to examine the patterns.”

Methods

L106–113: Consider moving the rationale for hospital selection to a bulleted list for clarity.

Participant criteria clear; statistical reasoning for sample size appropriate.

L138–141: “Never been published” not necessary unless relevant for novelty claim.

Translation and piloting described well; however, specify inter-rater reliability or quality control in data collection.

Variables section is detailed; some long sentences could be split for readability.

Statistical analysis description appropriate; mention if model diagnostics were performed.

Results

Tables are informative; ensure consistent decimal formatting and labeling.

L195–199: Minor grammar issues (“relapse rate was 69.5%”).

Figure 1 reference is good; ensure high-quality, clearly labeled figures for publication.

L215–227: Well-presented predictors; however, Table 5 should be integrated in-text with more interpretation.

Discussion

L229–237: Nicely summarizes key findings upfront.

Well-linked to literature, but several sentences are long and contain multiple ideas (e.g., L239–246). Breaking these will improve flow.

Strong point on post-hospital religious center visits; valuable policy implication.

L268–277: Good integration of recommendations for collaborative models. Could emphasize feasibility and examples from similar contexts.

L278–291: Highlights cultural determinants effectively; could add a brief comment on stigma reduction strategies.

L292–305: Limitations are well-acknowledged; however, some phrasing is defensive (“may affect the responses of participants”). Instead, frame as neutral methodological constraint.

Could mention potential recall bias due to self-reported pathways.

Reviewer #5: The topic is important and the dataset is valuable, but the current manuscript overreaches the design and under‑specifies the analysis. With the reanalysis, clearer definitions/reporting, and toned‑down interpretation, it could become publishable.

Firstly the main claim of the study implies a causal association between beliefs and referrals and use of primary healthcare system and yet the study design is cross-sectional. This is Moreso given that the sampling method had no randomization and introduces potential bias. I would suggest that the authors consider a more conservative claim and do so consistently from title, abstract to discussion. Below are some specific observations of areas they can tighten

L230 (“we sought to determine the patterns and determinants…”)

Issue: “Determine” implies causality.

Possible Fix: “we sought to describe patterns and identify factors associated with pathways…”

“After treatment successes” implies efficacy and temporal sequence not established.

Fix (replace L235–237):

“Among those presenting to psychiatric hospitals, 359/402 (89.2%) reported self‑referral. Of those whose first contact was a hospital (n= [insert]), ~1/3 reported subsequently consulting a religious center. These self‑reported sequences are subject to recall error and do not establish treatment effectiveness.”

While the statistical approach is well suited to cross-sectional categorical data, the conclusions that are arrived at from the significance are faulty in that they establish causality. While multinomial logistic regression is appropriate for categorical outcomes, the analysis overlooks repeated measures, clustering by hospital, sparse data bias, and multiple comparisons. Without addressing these and clarifying definitions, results risk bias and overinterpretation. Re-analysis with robust, stage-aware methods and cautious interpretation is required.

Take care of repeated measures, the same participant may contribute data to multiple contact stages, but the model treats these as independent. This can underestimate standard errors. A stage-aware method (e.g., GEE or multilevel modelling with participant ID and hospital as clusters) would be more robust.

Possibly consider clustering by hospital, participants are nested within nine hospitals, which may share referral patterns or patient profiles. Ignoring this clustering risks overstating precision. Cluster-robust SEs or random effects are recommended.

L216–220

Unit of analysis and model not fully clear for stage‑specific outcomes; repeated measures likely (same person contributes multiple “contact points”), yet independence is implied.

This is an issue because it violated independence inflates Type I error and narrows CIs.

You may correct by stating the modeling approach and address dependence (GEE or mixed‑effects) and hospital clustering; clarify that stage models are conditional on reaching that stage.

My suggested way to correct is to add after L216

“We modeled stage‑specific outcomes conditional on participants having reached that stage. To account for repeated measures across stages and clustering by hospital, we used [GEE with logit link and exchangeable correlation / mixed‑effects logistic regression with random intercepts for participant and hospital]. Results are reported as adjusted odds ratios (aOR) with cluster‑robust 95% CIs.”

Below are some other very specific observations and suggestions on how the authors may strengthen the analysis

L217–218 (“God’s punishment” aOR=4.68, CI 1.24–30.71, p=0.05)

Issue: Very wide CI and borderline p; precision is low; multiple testing not acknowledged.

Why: Risk of false positives and sparse‑data bias.

Action: Flag imprecision; consider penalized methods (Firth) or category collapse if sparse.

You may replace sentence:

“Attributing challenges to God’s punishment was associated with higher odds of non‑primary first contact (aOR 4.68, 95% CI 1.24–30.71). Given the wide CI and multiple comparisons, this estimate is imprecise and should be interpreted cautiously.”

L218 (witchcraft aOR=2.35, CI 1.06–5.45, p=0.04)

Issue: Same concerns; maintain associative language.

Fix (append): “A similar association was observed for witchcraft attributions (aOR 2.35, 95% CI 1.06–5.45).”

**********

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Reviewer #1: No

Reviewer #2: No

Reviewer #3: Yes:  Dr. Mohammad Ismail Bhuiyan

Reviewer #4: No

Reviewer #5: Yes:  Efison Dhodho

**********

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PLOS Glob Public Health. doi: 10.1371/journal.pgph.0006715.r003

Decision Letter 1

Collins Asweto, Helen Howard

4 Feb 2026

PGPH-D-25-01441R1

Beliefs, Referrals, and Mental Healthcare Pathways in the Eastern Democratic Republic of Congo

PLOS Global Public Health

Dear Dr. Mutume Nzanzu Vivalya,

Thank you for submitting your manuscript to PLOS Global Public Health. After careful consideration, we feel that it has merit but does not fully meet PLOS Global Public Health’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Mar 21 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at globalpubhealth@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pgph/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

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We look forward to receiving your revised manuscript.

Kind regards,

Helen Howard

Staff Editor

PLOS Global Public Health

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Reviewer #3: All comments have been addressed

Reviewer #6: All comments have been addressed

**********

-->2. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.-->

Reviewer #3: Yes

Reviewer #6: Yes

**********

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Reviewer #3: Yes

Reviewer #6: Yes

**********

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Reviewer #3: Yes

Reviewer #6: No

**********

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PLOS Global Public Health does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.-->

Reviewer #3: Yes

Reviewer #6: No

**********

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Reviewer #3: (No Response)

Reviewer #6: See attachment

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Reviewer #3: Yes:  Dr Mohammad Ismail Bhuiyan

Reviewer #6: No

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Attachment

Submitted filename: PlosGHDRC.docx

pgph.0006715.s004.docx (16.7KB, docx)
PLOS Glob Public Health. doi: 10.1371/journal.pgph.0006715.r005

Decision Letter 2

Collins Asweto, Helen Howard, Alejandro Torrado Pacheco

6 Apr 2026

PGPH-D-25-01441R2

Beliefs, Referrals, and Mental Healthcare Pathways in the Eastern Democratic Republic of Congo

PLOS Global Public Health

Dear Dr. Mutume Nzanzu Vivalya,

Thank you for submitting your manuscript to PLOS Global Public Health. After careful consideration, we feel that it has merit but does not fully meet PLOS Global Public Health’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

The manuscript has been evaluated by two reviewers. Reviewer 7 notes several significant issues with the reporting of the statistical analysis. Could you please address all of their comments carefully?

Please submit your revised manuscript by May 16 2026 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at globalpubhealth@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pgph/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

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Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

As the corresponding author, your ORCID iD is verified in the submission system and will appear in the published article. PLOS supports the use of ORCID, and we encourage all coauthors to register for an ORCID iD and use it as well. Please encourage your coauthors to verify their ORCID iD within the submission system before final acceptance, as unverified ORCID iDs will not appear in the published article. Only  the individual author can complete the verification step; PLOS staff cannot  verify ORCID iDs on behalf of authors.

We look forward to receiving your revised manuscript.

Kind regards,

Alejandro Torrado Pacheco, PhD

PLOS Editor

PLOS Global Public Health

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Reviewer #6: All comments have been addressed

Reviewer #7: (No Response)

**********

-->2. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.-->

Reviewer #6: (No Response)

Reviewer #7: No

**********

-->3. Has the statistical analysis been performed appropriately and rigorously?-->

Reviewer #6: Yes

Reviewer #7: No

**********

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Reviewer #6: Yes

Reviewer #7: No

**********

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Reviewer #6: Yes

Reviewer #7: No

**********

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Reviewer #6: I am satisfied that my concerns have been addressed.

Reviewer #7: The investigators conducted a cross-sectional survey involving patients who attended nine psychiatric hospitals in war torn Eastern DRC between 15th August and 15th December 2021.

Previous reviews of the manuscript seem to focus on the needed procedural clarification and clarity of some explanations and possible connectiveness of the psychiatric , religious, supernatural and medical issues. The statistical clarity overall is lacking despite the section on the Data processing and analysis plan. What about the ordering of type of contact if the numbers are sufficient to do so? See page 5. This is not really explained in the appendix. I can’t open the ‘sav’ file if the pathway is any help.

The analysis is not clearly presented as well. They used a hierarchical separate binary logistic regression model by fitting for each contact stage, to identify factors associated with the first, second, third, and fourth point of contact, all dichotomized into the two categories (PHC system and non-PHC system), recognizing first contact motivations may differ from those guiding later decisions. This is totally confusing and needs expansion. If this is Table 2 (Predictors of seeking mental health services in non-primary health care facilities) then the affect of the ordering is certainly not clear for either the PHC or NPHC data.

Also are the numbers sufficient for the variables or confounders considered in the models. What exactly is the content of the predictors in the models? The limitations in the ‘Discussion’ may need expansion to explain this. The entire statistical presentation needs a thorough edit for clarity.

**********

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Reviewer #6: Yes:  David Eagle

Reviewer #7: No

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PLOS Glob Public Health. doi: 10.1371/journal.pgph.0006715.r007

Decision Letter 3

Collins Asweto, Helen Howard, Alejandro Torrado Pacheco, Julia Robinson

5 Jun 2026

Beliefs, Referrals, and Mental Healthcare Pathways in the Eastern Democratic Republic of Congo

PGPH-D-25-01441R3

Dear Dr Mutume Nzanzu Vivalya,

We are pleased to inform you that your manuscript 'Beliefs, Referrals, and Mental Healthcare Pathways in the Eastern Democratic Republic of Congo ' has been provisionally accepted for publication in PLOS Global Public Health.

Before your manuscript can be formally accepted you will need to complete some formatting changes, which you will receive in a follow up email. A member of our team will be in touch with a set of requests.

Please note that your manuscript will not be scheduled for publication until you have made the required changes, so a swift response is appreciated.

IMPORTANT: The editorial review process is now complete. PLOS will only permit corrections to spelling, formatting or significant scientific errors from this point onwards. Requests for major changes, or any which affect the scientific understanding of your work, will cause delays to the publication date of your manuscript.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they'll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact globalpubhealth@plos.org.

Thank you again for supporting Open Access publishing; we are looking forward to publishing your work in PLOS Global Public Health.

Best regards,

Julia Robinson

Executive Editor

PLOS Global Public Health

***********************************************************

Reviewer Comments (if any, and for reference):

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Reviewer #7: All comments have been addressed

**********

-->2. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.-->

Reviewer #7: Yes

**********

-->3. Has the statistical analysis been performed appropriately and rigorously?-->

Reviewer #7: Yes

**********

-->4. Have the authors made all data underlying the findings in their manuscript fully available (please refer to the Data Availability Statement at the start of the manuscript PDF file)?

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Reviewer #7: Yes

**********

-->5. Is the manuscript presented in an intelligible fashion and written in standard English?

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Reviewer #7: Yes

**********

-->6. Review Comments to the Author

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Reviewer #7: All comments of a descriptive nature have been met.

**********

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Reviewer #7: No

**********

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 Table. Distribution of study participants per psychiatric hospital.

    (DOCX)

    pgph.0006715.s001.docx (17.2KB, docx)
    S1 Data. Dataset.

    (XLSX)

    pgph.0006715.s002.xlsx (51.1KB, xlsx)
    Attachment

    Submitted filename: responses to reviewers 23.10.2025.pdf

    pgph.0006715.s003.pdf (207KB, pdf)
    Attachment

    Submitted filename: PlosGHDRC.docx

    pgph.0006715.s004.docx (16.7KB, docx)
    Attachment

    Submitted filename: responses to reviewers 28.2.2026.pdf

    pgph.0006715.s005.pdf (144.1KB, pdf)
    Attachment

    Submitted filename: Responses to reviewers 2.pdf

    pgph.0006715.s006.pdf (108KB, pdf)

    Data Availability Statement

    The dataset used to support the findings of this study are available from the corresponding author and have been deposed in a public repository (Supporting information).


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