Abstract
The effects of d-amphetamine on punished responding were studied in two experiments. In Experiment I, pigeons responded under a multiple fixed-ratio 30 response fixed-interval 5-min schedule of food presentation with 60-sec limited holds in both components. Each response was punished with electric shock, the intensity of which was varied systematically. In Experiment II, another group of pigeons responded under a multiple fixed-interval 5-min fixed-interval 5-min schedule of food presentation with 40-sec limited holds. Each response was punished with shock during one component, and every thirtieth response was punished in the other component. d-Amphetamine increased overall rates of punished responding only rarely under any of the punishment conditions; however, response rates within the fixed-interval when rates were low were increased by d-amphetamine when the shock intensity was low (Experiment I), or when responses produced shock intermittently (Experiment II). The data suggest that the effects of d-amphetamine on punished responding depend on the control rate of responding, the punishment intensity, the punishment frequency, and the schedule of food presentation.
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- AZRIN N. H. A technique for delivering shock to pigeons. J Exp Anal Behav. 1959 Apr;2:161–163. doi: 10.1901/jeab.1959.2-161. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Clark F. C., Steele B. J. Effects of D-amphetamine on performance under a multiple schedule in the rat. Psychopharmacologia. 1966;9(2):157–169. doi: 10.1007/BF00404720. [DOI] [PubMed] [Google Scholar]
- DEWS P. B. Analysis of effects of psychopharmacological agents in behavioral terms. Fed Proc. 1958 Dec;17(4):1024–1030. [PubMed] [Google Scholar]
- HENDRY D. P., VANTOLLER C. FIXED-RATIO PUNISHMENT WITH CONTINUOUS REINFORCEMENT. J Exp Anal Behav. 1964 Jul;7:293–300. doi: 10.1901/jeab.1964.7-293. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hanson H. M., Witoslawski J. J., Campbell E. H. Drug effects in squirrel monkeys trained on a multiple schedule with a punishment contingency. J Exp Anal Behav. 1967 Nov;10(6):565–569. doi: 10.1901/jeab.1967.10-565. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kelleher R. T., Morse W. H. Determinants of the specificity of behavioral effects of drugs. Ergeb Physiol. 1968;60:1–56. doi: 10.1007/BFb0107250. [DOI] [PubMed] [Google Scholar]
- McMillan D. E. Drugs and punished responding. I. Rate-dependent effects under multiple schedules. J Exp Anal Behav. 1973 Jan;19(1):133–145. doi: 10.1901/jeab.1973.19-133. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McMillan D. E. Effects of d-amphetamine on performance under several parameters of multiple fixed-ratio, fixed-interval schedules. J Pharmacol Exp Ther. 1969 May;167(1):26–33. [PubMed] [Google Scholar]
- McMillan D. E. The effects of sympathomimetic amines on schedule-controlled behavior in the pigeon. J Pharmacol Exp Ther. 1968 Apr;160(2):315–325. [PubMed] [Google Scholar]
- Morrison C. F. The effects of nicotine on punished behaviour. Psychopharmacologia. 1969;14(3):221–232. doi: 10.1007/BF00404220. [DOI] [PubMed] [Google Scholar]
- SMITH C. B. EFFECTS OF D-AMPHETAMINE UPON OPERANT BEHAVIOR OF PIGEONS: ENHANCEMENT BY RESERPINE. J Pharmacol Exp Ther. 1964 Nov;146:167–174. [PubMed] [Google Scholar]