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PLOS One logoLink to PLOS One
. 2026 Jul 8;21(7):e0352982. doi: 10.1371/journal.pone.0352982

Knowledge, attitudes, and practices regarding type 2 diabetes and associated factors among rural adolescents in Indonesia: A cross-sectional study

Nila Kusumawati 1,2,*, Hanno Pijl 3, Halimatou Alaofè 1, Emul Yani 4, Desti Puswati 4, Abdul Hamid 2
Editor: Cho Lee Wong5
PMCID: PMC13345253  PMID: 42418453

Abstract

Introduction

Type 2 diabetes (T2D) is an increasingly important public health concern in Indonesia and is increasingly affecting adolescents at a growing rate due to lifestyle transitions and limited awareness. Evidence regarding adolescents’ knowledge, attitudes, and practices (KAP) toward T2D in rural settings remains limited. This study assessed KAP levels related to T2D, identified sociodemographic factors associated with KAP outcomes, and examined interrelationships among KAP domains among rural Indonesian adolescents.

Methods

A cross-sectional study was conducted from September 2024 to February 2025 among 1,546 senior high school students in Kampar Regency, Riau Province. Participants were selected using multistage cluster sampling. Data were collected using a validated KAP questionnaire (Cronbach’s α = 0.725). Descriptive and inferential statistics, including Mann–Whitney U tests, Kruskal–Wallis tests, Spearman’s rank correlations, and multiple linear regression analyses, were used to examine KAP outcomes and associated factors.

Results

Participants demonstrated limited knowledge regarding T2D, particularly related to risk factors, symptoms, and complications. Although attitudes toward diabetes prevention were generally positive, preventive practices remained suboptimal, especially regarding physical activity. Female gender, peri-urban school location, higher academic rank, extracurricular participation, and prior exposure to diabetes information were associated with higher KAP scores. Knowledge was moderately associated with attitude but only weakly associated with preventive practices.

Conclusions

Rural adolescents demonstrated limited diabetes-related knowledge and suboptimal preventive behaviors despite generally positive attitudes toward T2D prevention. Several sociodemographic and school-related factors were associated with KAP outcomes. However, the weak relationship between knowledge and practice highlights a persistent gap between awareness and preventive behavior. School-based, peer-led, and after-school interventions that integrate education with behavioral reinforcement may strengthen diabetes prevention efforts among rural adolescents.

Introduction

Type 2 diabetes (T2D) is a major non-communicable disease in Indonesia, contributing significantly to national morbidity and mortality rates [1–2]. According to the International Diabetes Federation Diabetes Atlas (2025), Indonesia ranks fifth globally in diabetes prevalence among adults aged 20–79 and third for undiagnosed cases. The number of people affected by diabetes and its complications is expected to continue rising [1]. Diabetes is also the fifth leading cause of death among non-communicable diseases in the country [3]. A national study reported that 4% of the 18.9 million enrollees in Indonesia’s National Health Insurance were T2D patients, 57% of whom experienced complications. The direct medical costs of diabetes reached USD 576 million, with 74% of this expenditure dedicated to managing complications [4].

Although T2D was once regarded as an adult-onset disease, it is now increasingly diagnosed among adolescents worldwide [5,6]. Contributing risk factors such as obesity, physical inactivity, and smoking are becoming more prevalent among youth [7]. In rural Indonesia, these risks are compounded by low parental awareness of diabetes screening in adolescents and the widespread perception that T2D primarily affects older adults [8]. The COVID-19 pandemic has further worsened this situation by increasing screen time and reducing physical activity, resulting in higher body mass index (BMI) levels among adolescents [9–11]. Furthermore, the rapid expansion of internet access has contributed to greater digital engagement among adolescents, negatively influencing adolescent lifestyles in both urban and rural areas of Indonesia [12–14].

Reducing adolescents’ exposure to modifiable risk factors is crucial to curbing the future burden of T2D in Indonesia. Evidence suggests that effective prevention programs could reduce national diabetes rates to 9.22% [15]. Designing such interventions requires a clear understanding of adolescents’ knowledge, attitudes, and practices (KAP) related to T2D. Findings from other countries show wide disparities in KAP among adolescent populations. For instance, students in peri-urban areas of Bangladesh demonstrated greater diabetes-related knowledge than those in rural areas [16]; Nepalese metropolitan students showed higher knowledge, but similar attitudes compared to rural peers [17]; and Jordanian adolescents exhibited moderate to high knowledge but poor attitudes and practices [18]. In India, rural high school students displayed fair diabetes knowledge, though their attitudes and self-care behaviors were not assessed [19].

While many studies have examined adolescents’ knowledge and attitudes toward T2D, mainly in urban areas where risk factors are more pronounced, few studies have comprehensively assessed all three KAP domains in rural settings. Even less evidence exists on how sociodemographic factors such as gender, parental education, school type, and extracurricular participation shape these outcomes. Understanding these relationships is crucial for identifying groups at risk of limited awareness or unhealthy behaviors, addressing disparities in access to health information, and designing targeted health promotion strategies. Moreover, most adolescent KAP research in low- and middle-income countries remains descriptive, rarely analyzing interrelationships among KAP domains [16–22]. Exploring these linkages can clarify whether greater knowledge and positive attitudes translate into healthier practices, testing the applicability of the KAP framework.

This study aims to fill these gaps by assessing the levels of KAP related to T2D among rural adolescents in Indonesia; identifying sociodemographic factors associated with these outcomes; and examining the interrelationships among KAP domains. Understanding these relationships is vital for policymakers and educators to design culturally relevant, school-based interventions that promote early diabetes prevention. Strengthening diabetes awareness during adolescence can facilitate early risk identification, encourage healthier lifestyles, and reduce future disease burden. Additionally, this context-specific evidence may inform similar efforts in other low- and middle-income countries, where diabetes prevalence is projected to increase by 95% by 2050 [1]. This project underscores the urgency of developing locally grounded strategies to address the global rise of T2D.

Materials and methods

Study design, setting, and period

A cross-sectional study was conducted from September 18, 2024, to February 7, 2025, in Kampar Regency, Riau Province, Indonesia, to assess adolescents’ KAP related to T2D. Riau Province ranks 15th among Indonesia’s 38 provinces in diabetes prevalence, with a rate of 1.5%, slightly below the national average. Unhealthy lifestyle habits, including low physical activity and frequent consumption of sugary beverages, have been observed among children as young as three years old in the region [7,8,12,23]. Kampar Regency was chosen for its predominantly rural characteristics, relatively high diabetes burden, and large population of senior high school students [23].

Study population, sample size, and sampling

The study population comprised 21,872 senior high school students in Kampar Regency. Using OpenEpi version 3, the minimum sample size was calculated as 1,288 students based on a 50% anticipated frequency, 5% confidence limits, 99% confidence level, and a design effect of 2 to account for cluster sampling. After adjusting for a 20% non-response rate [24], the final sample included 1,546 students to improve statistical power and representativeness.

A multistage cluster sampling technique was used [25]. Eleven of the 21 districts in Kampar were randomly selected, followed by the random selection of one senior high school from each district. Within each school, students in grades 10 and 11 were proportionally recruited. Eligible participants were those attending school during data collection who voluntarily agreed to participate.

Data collection instrument and procedure

Data were collected using a pretested, structured KAP questionnaire adapted from previous studies on diabetes among adolescents, with additional context-specific variables included to reflect the local setting and study objectives [16–19]. The instrument underwent two stages of validation. First, face validity was assessed by two researchers. Second, content validity was reviewed by six experts in internal medicine, nursing, and public health. This process yielded an item-level content validity index (I-CVI) of 0.80 and a scale-level content validity index (S-CVI) of 0.90.

The questionnaire was pilot-tested among 420 students from three public schools that were not included in the main study. Item validity was supported by Pearson correlation coefficients ranging from 0.273 to 0.585. Construct validity was supported by a Kaiser–Meyer–Olkin (KMO) value of 0.779 and a significant Bartlett’s test of sphericity (p < 0.001). Internal consistency was acceptable, with Cronbach’s alpha of 0.725.

The final instrument, administered in Indonesian (S1 File) and translated into English for reporting purposes (S2 File), consisted of four sections:

Sociodemographic and anthropometric characteristics.

The first section assessed sociodemographic and anthropometric characteristics. Sociodemographic variables included age, gender, ethnicity, grade, class rank, school location, total daily school hours, extracurricular participation, parents’ education and employment, and family history of diabetes. Anthropometric measures included height and weight, from which BMI was calculated. Total daily school hours included both regular classroom hours and time spent at school after classes for social, transportation, or educational purposes before returning home. Family history was assessed using two questions: the presence of first-degree relatives with diabetes (none, yes, or no idea), and the number of affected relatives (none or one/more). Height and weight were measured by trained staff to the nearest 0.1 cm and 0.1 kg, respectively. BMI was categorized using the Indonesian classification based on World Health Organization cutoffs [24].

Knowledge domain.

The second section assessed knowledge of T2D using five questions covering causes, risk factors, symptoms, complications, and prevention. Some questions allowed multiple responses and were scored based on the number of correct responses selected. Each correct response was assigned 1 point.

Attitude domain.

The third section assessed attitudes using six statements related to diabetes prevention and risk factors. Positive responses were scored as 1, and negative or “do not know” responses were scored as 0.

Practice domain.

The fourth section assessed practices related to physical activity, smoking, and body weight monitoring. Responses were scored according to the frequency of these health-related behaviors, with higher scores indicating healthier practices. The maximum possible scores were 18 for knowledge, 6 for attitude, and 8 for practice, yielding a total KAP score of 32.

Data were collected in classrooms using self-administered paper questionnaires supervised by the authors and trained assistants from public health, nursing, nutrition, and midwifery programs. Questionnaires were reviewed onsite for completeness before collection, and participants were given the opportunity to review unanswered items during the data collection session.

Data entry was performed by trained research assistants under the supervision of the research team. Prior to data entry, assistants received standardized training on coding procedures, use of the study codebook, and quality control measures. The completed datasets were subsequently cross-checked for accuracy, consistency, and completeness by the research team, and data cleaning was conducted before statistical analysis.

Ethical considerations

Ethical approval was obtained from the Institutional Review Board of Institut Kesehatan Payung Negeri Pekanbaru, Riau Province, Indonesia (No. 277/IKES PN/KEPK/IX/2024). The study was conducted in accordance with the approved protocol, and no major deviations occurred during the study period. Permission to conduct data collection in schools was granted by the Provincial Department of Education (No.421/cabdisdik/6.2/2023/083), and additional written approvals were obtained from each participating school.

Participation was voluntary, and all participants were informed about the study’s purpose and procedures. Participants were informed that they could decline participation or withdraw from the study at any time without penalty. Written informed consent was obtained from students aged 17 years and older, witnessed by homeroom teachers. For students under 17 years, written parental or guardian consent and participant assent were required.

Questionnaires were anonymous, and no identifying information was collected. Completed questionnaires were coded and stored securely in a locked cabinet, while electronic data files were stored on password-protected personal computers. Both hard-copy and electronic data were accessible only to the research team and retained for up to three years after study completion. Data were analyzed and reported in aggregate form to maintain participant confidentiality.

Inclusivity in global research and reporting guidelines

Additional information regarding the ethical, cultural, and scientific considerations specific to inclusivity in global research is provided in the Supporting Information (S3 File). This study was also reported in accordance with the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) guidelines. The completed STROBE checklist is provided in the Supporting Information (S1 Checklist).

Statistical analysis

Descriptive statistics were used to summarize participants’ sociodemographic characteristics and KAP outcomes. Categorical variables were presented as frequencies (n) and percentages (%), while continuous variables with non-normal distributions were summarized using medians and interquartile ranges (IQRs). There were no missing data in the dataset.

For descriptive interpretation, individual knowledge, attitude, practice, and total KAP scores were converted into percentages of the maximum obtainable scores and categorized using modified Bloom’s cutoff criteria as low/negative (<60%), moderate/neutral (60%–79%), or high/positive (≥80%) [26]. These categories were used solely to describe KAP levels, while continuous KAP scores were retained for bivariate and multivariable analyses.

The Shapiro–Wilk test indicated that KAP scores were not normally distributed (p < 0.001); therefore, non-parametric tests were used for bivariate analyses. Spearman’s rank correlation was used to examine associations between age and KAP scores. The Mann–Whitney U test was used for comparisons between binary variables, such as gender and school location, while the Kruskal–Wallis test was used for variables with three or more categories, such as family history of T2D.

Multiple linear regression analyses were subsequently performed to identify sociodemographic predictors of KAP scores, with the composite scores treated as continuous outcomes. Linear regression was considered appropriate because the composite KAP scores were derived from multiple questionnaire items and demonstrated sufficient range and approximate continuity. In addition, regression diagnostics indicated that model assumptions were adequately met at the residual level. All measured sociodemographic variables were included simultaneously to adjust for potential confounding. Although multistage cluster sampling was used, analyses were conducted at the individual level.

Regression assumptions were evaluated systematically. Linearity assumptions were satisfied based on diagnostic assessment. Visual inspection of residual plots suggested approximate normality of residuals. Residual normality was considered acceptable for linear regression, particularly given the large sample size. Heteroskedasticity was detected using White’s test (p < 0.05) and was addressed using robust standard errors. Independence of observations was considered satisfied based on the study design. No multicollinearity was detected, with a mean variance inflation factor (VIF) of 1.17. No influential observations were identified based on Cook’s Distance (Cook’s D < 0.05). Diagnostic tests, including the Ramsey RESET and Link tests, showed no evidence of model misspecification (p > 0.05).

Finally, Spearman’s rank correlation was used to examine interrelationships among the KAP domains. All analyses were conducted using Stata Statistical Software, Release 19 (StataCorp LLC, College Station, TX, USA). A two-sided p-value < 0.05 was considered statistically significant.

Results

Participants’ sociodemographic characteristics

A total of 1,546 senior high school students participated in the study, with a median age of 16 years (IQR: 16–17). As shown in Table 1, nearly two-thirds of participants were female (64.0%), and the majority were non-obese (91.8%). Most students attended peri-urban schools (63.8%), spent more than 8 hours/day at school (93.3%), and did not participate in extracurricular activities (65.8%).

Table 1. Sociodemographic characteristics of the study participants (N = 1,546).

Characteristics n (%)
Gender
Male 557 (36.0)
Female 989 (64.0)
Ethnicity
Indigenous 834 (53.9)
Non-Indigenous 712 (46.1)
Body Mass Index
Obese 126 (8.2)
Non-obese 1,420 (91.8)
School Location
Remote rural 559 (36.2)
Peri-urban 987 (63.8)
Total Daily School Hours
≤8 hours/day 103 (6.7)
>8 hours/day 1,443 (93.3)
Grade Level
Grade X 716 (46.3)
Grade XI 830 (53.7)
Class Rank
Below top 10 942 (60.9)
Top 10 604 (39.1)
Extracurricular Participation
Not participating 1,017 (65.8)
Participating at least 1 day/week 529 (34.2)
Father’s Employment
Unemployed 114 (7.4)
Employed 1,432 (92.6)
Mother’s Employment
Unemployed 1,258 (81.4)
Employed 288 (18.6)
Father’s Education
Junior high school or below 583 (37.7)
Senior high school or above 963 (62.3)
Mother’s Education
Junior high school or below 596 (38.6)
Senior high school or above 950 (61.4)
First-degree Relatives’ T2D History
None 1,098 (71.0)
Yes 141 (9.1)
No idea 307 (19.9)
Received Information about T2D
Did not receive 364 (23.5)
Received 1,182 (76.5)

Regarding parental characteristics, 62.3% of fathers and 61.4% of mothers had at least a senior high school education. Fathers were more likely to be employed (92.6%) than mothers (18.6%). Almost 20% of adolescents were uncertain whether their first-degree relatives had T2D. Among participants reporting a family history of T2D, all reported at least one affected first-degree relative, most commonly their father (57.4%). Additionally, 23.5% of participants had not received any information about diabetes. Among those who had received information about diabetes, social media (48.8%), websites (42.3%), and school-based education (26.1%) were the most common information sources.

Knowledge of type 2 diabetes

As shown in Table 2, participants demonstrated partial knowledge of T2D. About 16.6% incorrectly believed it to be an infectious disease, while 22.4% were uncertain. Only 50.8% recognized physical inactivity as a risk factor, and 8.9% identified smoking as a risk factor. Awareness of common symptoms was also limited. While 53.0% recognized frequent urination, only 16.9% identified increased thirst and 16.2% identified frequent hunger. Knowledge of T2D complications varied. While 61.5% of participants identified foot problems as a complication, only 13.0% recognized diabetic retinopathy. Regarding preventability, 81.6% correctly indicated that T2D is preventable, although 15.7% were unsure and 2.7% believed it was not preventable.

Table 2. Participants’ diabetes-related knowledge (N = 1,546).

Questions and Selected Responses n %
T2D is an infectious disease
Yes 256 16.6
No 943 61.0
Do not know 347 22.4
T2D risk factors
Obesity 603 39.0
Physical inactivity 785 50.8
Family history 814 52.7
Stress 140 9.1
Smoking 137 8.9
T2D signs and symptoms
Frequent urination 819 53.0
Tiredness 570 36.9
Increased thirst 262 16.9
Increased hunger 250 16.2
Unintended weight loss 543 35.1
T2D complications
Diabetic retinopathy 201 13.0
Diabetic kidney disease 434 28.1
Foot problems 951 61.5
Nerve damage 323 20.9
Heart disease 229 14.8
Stroke 207 13.4
T2D is preventable
Yes 1,262 81.6
No 42 2.7
Do not know 242 15.7

Attitudes toward type 2 diabetes

Participants’ attitudes toward diabetes prevention and T2D risk factors are presented in Table 3. Most adolescents expressed positive attitudes toward prevention, with 91.1% agreeing that healthy eating is important and 89.1% acknowledging the role of exercise in T2D prevention. However, misconceptions persisted. Nearly 28% were unsure whether having a family history increases T2D risk, and 27.7% disagreed. Likewise, 24.4% disagreed that smoking raises the risk, and 43.0% were uncertain. Approximately one-quarter (24.8%) of participants were unsure of the role of obesity in increasing T2D risk.

Table 3. Participants’ diabetes-related attitudes (N = 1,546).

Questions and Selected Responses n %
Healthy eating is important to prevent T2D
Agree 1,408 91.1
Disagree 19 1.2
Not sure 119 7.7
Exercise helps prevent T2D
Agree 1,378 89.1
Disagree 30 1.9
Not sure 138 8.9
If you have a family history of T2D, you are at higher risk of getting it
Agree 677 43.8
Disagree 428 27.7
Not sure 441 28.5
People who smoke are more likely to get T2D
Agree 503 32.6
Disagree 377 24.4
Not sure 655 43.0
Regular screening helps in the early detection and prevention of T2D
Agree 1,273 82.3
Disagree 43 2.8
Not sure 230 14.9
Obesity increases the risk of developing T2D
Agree 1,034 66.9
Disagree 129 8.3
Not sure 383 24.8

Preventive practices related to type 2 diabetes

Preventive practices related to T2D varied across behaviors (Table 4). Only 17.5% of adolescents engaged in at least 60 minutes of daily physical activity, whereas 66.0% were active for 30 minutes or less per day, and 16.5% reported no physical activity. Although 91.5% of participants were non-smokers, 6.4% reported smoking fewer than 25 cigarettes per day, and 2.1% reported smoking 25 or more cigarettes per day. Regarding weight monitoring, only 5.0% checked their weight daily, whereas 16.0% did so annually, and 3.8% never monitored their weight.

Table 4. Participants’ diabetes-related practices (N = 1,546).

Questions and Selected Responses n %
Daily Physical Activity
None 255 16.5
30 minutes or less 1021 66.0
60 minutes or more 270 17.5
Cigarette Consumption per Day
Never 1,414 91.5
Less than 25 99 6.4
25 or more 33 2.1
Frequency of Body Weight Monitoring
Never 58 3.8
Once a year 248 16.0
Once every few months 540 34.9
Once a month 404 26.1
Once a week 219 14.2
Every day 77 5.0

Overall knowledge, attitude, and practice levels

The median (IQR) knowledge score was 5 (4–7) out of a possible score of 18, with most participants (92.4%) classified as having low knowledge levels regarding T2D. The median (IQR) attitude score was 4 (3–5) out of a possible score of 6, and 42.9% of participants demonstrated positive attitudes toward T2D prevention. The median (IQR) practice score was 4 (3–5) out of a possible score of 8, with more than half of participants (55.5%) categorized as having low practice levels. The median overall KAP score was 14 (12–17) out of a possible score of 32, and most participants (89.1%) demonstrated low overall KAP levels related to T2D (Table 5).

Table 5. Distribution of knowledge, attitude, practice, and overall KAP levels (N = 1,546).

Domain Low n (%) Moderate n (%) High n (%)
Knowledge 1,429 (92.4) 102 (6.6) 15 (1.0)
Attitude 459 (29.7) 423 (27.4) 664 (42.9)
Practice 858 (55.5) 585 (37.8) 103 (6.7)
Total KAPa 1,377 (89.1) 158 (10.2) 11 (0.7)

aKAP: knowledge, attitude, and practice.

KAP levels were categorized using modified Bloom’s cutoff criteria as low (<60%), moderate (60%–79%), or high (≥80%).

Factors associated with knowledge, attitude, and practice

Bivariate analysis.

Bivariate analyses (S1 Table) revealed significant associations between several sociodemographic factors and KAP domains. Gender, school location, grade level, extracurricular participation, parental education, and exposure to diabetes information were significantly related to knowledge, attitude, and overall KAP scores (all p < 0.05), but not to practice scores. Longer school hours and higher class rank were significantly associated with multiple KAP domains, whereas obesity status and parental employment showed no significant associations. Participants reporting a family history of T2D had higher attitude and overall KAP scores than those without such history or who were uncertain about their family history status. Adolescents who were uncertain about their family’s T2D status generally exhibited the lowest KAP scores across domains.

Multivariable analysis of sociodemographic factors.

After adjustment for all covariates, several sociodemographic variables remained significantly associated with knowledge scores.

Knowledge.

Female students scored, on average, approximately 0.5 points higher on the knowledge scale than male students (B = 0.50, 95% CI 0.24–0.77, p < 0.001). Non-Indigenous students also demonstrated higher knowledge scores than Indigenous students (B = 0.80, 95% CI 0.53–1.07, p < 0.001). Higher knowledge scores were additionally observed among students attending peri-urban schools (B = 0.46, 95% CI 0.17–0.74, p = 0.002), those in Grade XI (B = 0.33, 95% CI 0.02–0.64, p = 0.040), students ranked in the top 10 of their class (B = 0.55, 95% CI 0.27–0.83, p < 0.001), participants in extracurricular activities (B = 0.72, 95% CI 0.43–1.00, p < 0.001), students whose fathers had at least a senior high school education (B = 0.34, 95% CI 0.05–0.63, p = 0.020), and those previously exposed to diabetes-related information (B = 0.48, 95% CI 0.20–0.75, p = 0.001). In contrast, students who were uncertain about their family’s diabetes history demonstrated lower knowledge scores (B = –0.36, 95% CI –0.66 to –0.05, p = 0.020).

Attitude.

Higher attitude scores were observed among female students (B = 0.35, 95% CI 0.20–0.50, p < 0.001), peri-urban school attendees (B = 0.29, 95% CI 0.15–0.43, p < 0.001), students spending more than 8 hours/day at school (B = 0.51, 95% CI 0.21–0.81, p = 0.001), those in Grade XI (B = 0.21, 95% CI 0.04–0.37, p = 0.013), and students ranked in the top 10 of their class (B = 0.20, 95% CI 0.06–0.35, p = 0.005). Students participating in extracurricular activities (B = 0.24, 95% CI 0.10–0.39, p = 0.001) and those previously exposed to diabetes-related information (B = 0.34, 95% CI 0.17–0.52, p < 0.001) also demonstrated more favorable attitude scores toward T2D prevention and risk factors. Conversely, students uncertain about their family’s diabetes history demonstrated lower attitude scores (B = –0.20, 95% CI –0.38 to –0.01, p = 0.040).

Practice.

Higher practice scores were observed among students attending peri-urban schools (B = 0.16, 95% CI 0.02–0.30, p = 0.030), those spending more than 8 hours per day at school (B = 0.69, 95% CI 0.43–0.94, p < 0.001), and students ranked in the top 10 of their class (B = 0.24, 95% CI 0.10–0.38, p = 0.001). Students uncertain about their family’s diabetes history again demonstrated lower practice scores (B = –0.18, 95% CI –0.34 to –0.01, p = 0.040).

Overall KAP.

Higher overall KAP scores were observed among female (B = 0.88, 95% CI 0.49–1.26, p < 0.001) and non-Indigenous students (B = 0.93, 95% CI 0.55–1.30, p < 0.001), as well as among students attending peri-urban schools (B = 0.90, 95% CI 0.50–1.30, p < 0.001), those spending more than 8 hours per day at school (B = 1.26, 95% CI 0.41–2.11, p = 0.004), students in higher grade level (B = 0.54, 95% CI 0.10–0.98, p = 0.015), those ranked in the top 10 of their class (B = 0.99, 95% CI 0.60–1.39, p < 0.001), and participants in extracurricular activities (B = 1.01, 95% CI 0.62–1.40, p < 0.001). Higher paternal education (B = 0.45, 95% CI 0.04–0.86, p = 0.03) and prior exposure to diabetes-related information (B = 0.85, 95% CI 0.43–1.26, p < 0.001) were also associated with higher overall KAP scores. In contrast, adolescents uncertain about their family’s diabetes history consistently demonstrated lower overall KAP scores (B = –0.73, 95% CI –1.18 to –0.28, p = 0.002).

Although the observed effect sizes were generally modest in magnitude, several associations were consistently identified across the knowledge, attitude, practice, and overall KAP domains. Given the multifactorial nature of health knowledge and behaviors, even relatively small differences in KAP scores across adolescent populations may be meaningful at the population level, particularly for informing targeted diabetes education and prevention strategies among vulnerable adolescent groups (Table 6).

Table 6. Associations between sociodemographic characteristics and KAP scores (N = 1,546).
Variables Knowledge Attitude Practice Overall KAP
B (95% CI),

p
B (95% CI),

p
B (95% CI),

p
B (95% CI),

p
Age 0.02 (–0.17, 0.22), 0.81 0.05 (–0.06, 0.16), 0.38 –0.02 (–0.12, 0.08), 0.72 0.06 (–0.22, 0.34), 0.69
Gender
Male Ref Ref Ref Ref
Female 0.50 (0.24, 0.77), < 0.001 0.35 (0.20, 0.50), < 0.001 0.03 (–0.12, 0.17), 0.71 0.88 (0.49, 1.26), < 0.001
Ethnicity
Indigenous Ref Ref Ref Ref
Non-Indigenous 0.80 (0.53, 1.07), < 0.001 0.14 (0.00, 0.28), 0.06 –0.01 (–0.15, 0.12), 0.85 0.93 (0.55, 1.30), < 0.001
Body mass index
Obese Ref Ref Ref Ref
Non-obese –0.21 (–0.65, 0.24), 0.37 –0.10 (–0.33, 0.12), 0.38 –0.22 (–0.46, 0.02), 0.08 –0.53 (–1.17, 0.12), 0.11
School location
Remote rural Ref Ref Ref Ref
Peri-urban 0.46 (0.17, 0.74),

0.002
0.29 (0.15, 0.43), <0.001 0.16 (0.02, 0.30), 0.03 0.90 (0.50, 1.30), <0.001
Total daily school hours
≤8 hours Ref Ref Ref Ref
>8 hours 0.06 (–0.51, 0.64), 0.83 0.51 (0.21, 0.81), <0.001 0.69 (0.43, 0.94), <0.001 1.26 (0.41, 2.11), 0.004
Grade level
Grade X Ref Ref Ref Ref
Grade XI 0.33 (0.02, 0.64),

0.04
0.21 (0.04, 0.37),

0.01
0.01 (–0.16, 0.17),

0.95
0.54 (0.10, 0.98),

0.02
Class rank
Below top 10 Ref Ref Ref Ref
Top 10 0.55 (0.27, 0.83),

<0.001
0.20 (0.06, 0.35),

0.01
0.24 (0.10, 0.38),

<0.001
0.99 (0.60, 1.39),

<0.001
Extracurricular participation
Not participating Ref Ref Ref Ref
Participating at least 1 day/week 0.72 (0.43, 1.00),

<0.001
0.24 (0.10, 0.39),

0.001
0.05 (–0.09, 0.19),

0.48
1.01 (0.62, 1.40),

<0.001
Father’s education
Junior high school or below Ref Ref Ref Ref
Senior high school or above 0.34 (0.05, 0.63),

0.02
0.08 (–0.08, 0.24),

0.34
0.03 (–0.12, 0.18),

0.72
0.45 (0.04, 0.86),

0.03
Mother’s education
Junior high school or below Ref Ref Ref Ref
Senior high school or above 0.00 (–0.29, 0.30),

0.98
0.08 (–0.09, 0.24),

0.36
0.04 (–0.11, 0.20),

0.58
0.12 (–0.30, 0.54),

0.56
Father’s employment
Unemployed Ref Ref Ref Ref
Employed 0.18 (–0.27, 0.64), 0.43 0.07 (–0.21, 0.35), 0.62 –0.11 (–0.37, 0.16), 0.43 0.15 (–0.53, 0.83), 0.67
Mother’s employment
Unemployed Ref Ref Ref Ref
Employed 0.08 (–0.26, 0.42), 0.65 –0.05 (–0.23, 0.12), 0.55 –0.07 (–0.25, 0.11), 0.44 –0.04 (–0.53, 0.45), 0.87
First-degree relatives with T2Da history
None Ref Ref Ref Ref
Yes 0.19 (–0.27, 0.65), 0.41 0.19 (–0.03, 0.41), 0.08 0.03 (–0.22, 0.27), 0.84 0.41 (–0.22, 1.04), 0.20
No idea –0.36 (–0.66, –0.05), 0.02 –0.20 (–0.38, –0.01), 0.04 –0.18 (–0.34, –0.01), 0.04 –0.73 (–1.18, –0.28), 0.001
Received information about T2D
Not received Ref Ref Ref Ref
Received 0.48 (0.20, 0.75), 0.001 0.34 (0.17, 0.52), <0.001 0.03 (–0.13, 0.19), 0.73 0.85 (0.43, 1.26), <0.001

Values are presented as regression coefficients (B) with 95% confidence intervals.

Reference categories are indicated as “Ref”.

a T2D: Type 2 diabetes.

Model fit statistics: Knowledge, F(16,1529) = 13.19, p < 0.001, R² = 0.110; Attitude, F(16,1529) = 9.77, p < 0.001, R² = 0.093; Practice, F(16,1529) = 3.68, p < 0.001, R² = 0.034; Overall KAP, F(16,1529) = 16.36, p < 0.001, R² = 0.143.

Interrelationships among KAP domains

As shown in Table 7, Spearman’s rank correlation analysis demonstrated significant positive associations among KAP domains (all p < 0.05). Knowledge was moderately correlated with attitude (ρ = 0.424), whereas correlations between knowledge and practice (ρ = 0.052) and between attitude and practice (ρ = 0.117) were weak. Knowledge, attitude, and practice scores were all positively correlated with overall KAP scores, with the strongest correlation observed between knowledge and overall KAP (ρ = 0.817). These findings suggest that although knowledge and attitudes toward T2D were positively related, their associations with preventive practices were relatively weak.

Table 7. Intercorrelations among KAP domains.

KAP Domains Spearman’s ρ (p-value)
Knowledge – Attitude 0.424 (<0.001)
Knowledge – Practice 0.052 (0.040)
Attitude – Practice 0.117 (<0.001)
Knowledge – Overall KAP 0.817 (<0.001)
Attitude – Overall KAP 0.706 (<0.001)
Practice – Overall KAP 0.438 (<0.001)

Discussion

This study examined KAP related to T2D among rural Indonesian adolescents. It also identified sociodemographic factors associated with KAP outcomes and explored interrelationships among the domains. The findings revealed generally low levels of diabetes-related knowledge and suboptimal engagement in preventive practices among adolescents. Although some participants demonstrated favorable attitudes toward T2D prevention, overall KAP levels remained low. These findings suggest that positive attitudes alone may not be sufficient to promote healthy preventive behaviors in the absence of adequate knowledge and supportive environments for behavioral change. They also underscore the need for school-based interventions that strengthen diabetes-related understanding while promoting sustainable behavioral change among adolescents.

Knowledge and attitudes toward T2D

Adolescents demonstrated limited knowledge of T2D, particularly regarding smoking as a risk factor and symptoms such as excessive thirst and hunger. Similar knowledge gaps have been reported among adolescents and school students in rural India, Nepal, Bangladesh, Kuwait, and Saudi Arabia, especially regarding T2D risk factors and symptoms [16,17,19,27,28]. Although most participants recognized that T2D is preventable, many remained uncertain about its causes and complications. Additionally, nearly one-quarter of participants had never received any information about diabetes, and school-based education was reported less frequently than social media and websites as a source of diabetes-related information. These findings suggest that existing school-based health education may not provide sufficient depth or interactive learning opportunities to support comprehensive diabetes-related understanding.

Despite these knowledge gaps, many participants expressed favorable attitudes toward diabetes prevention and acknowledged the importance of healthy eating and physical activity. This finding is consistent with studies from rural Nepal and Bangladesh, where adolescents reported positive attitudes despite relatively limited knowledge levels [16,17]. These positive attitudes may serve as an important foundation for future diabetes prevention efforts among rural adolescents. However, misconceptions regarding smoking and family history as risk factors indicate that some adolescents still hold inaccurate or inconsistent beliefs about T2D causation. Such misconceptions may hinder the translation of positive attitudes into effective preventive behaviors.

Knowledge and preventive practices

This study revealed low levels of both diabetes-related knowledge and preventive practices among adolescents. In addition, the correlation between knowledge and practice was the weakest among the KAP domain relationships. Although approximately half of participants recognized physical inactivity as a risk factor for T2D, only 17.5% met the recommended 60 minutes of daily physical activity. Similar findings have been reported in Nepal, Ethiopia, and Indonesia, where physical inactivity among adolescents remains common [20,29,30].

These findings suggest that awareness alone is insufficient to support behavioral change and that adolescent health behaviors are shaped by broader environmental and sociocultural influences. Low physical activity levels may be influenced by hot weather conditions, limited peer and parental support for active lifestyles, and gender-related preferences to avoid outdoor activity [20,29,30]. Adolescents may also view T2D primarily as a disease affecting older adults, potentially reducing their perceived susceptibility and motivation to engage in preventive behaviors [8]. Although smoking prevalence was relatively low, adolescents who smoked tended to consume relatively large numbers of cigarettes, possibly reflecting the continued accessibility and social acceptability of tobacco use among Indonesian youth [31]. Together, these factors may hinder the adoption of healthy preventive behaviors despite some awareness of diabetes prevention practices.

These findings highlight the need for multifaceted interventions that go beyond information provision. Health promotion efforts should also strengthen behavioral skills, motivation, and supportive social environments. Strategies such as experiential learning, goal setting, and peer modeling may help reinforce the link between awareness and healthy behaviors among adolescents.

Influence of sociodemographic factors

Sociodemographic characteristics significantly influenced KAP outcomes. Female students consistently demonstrated higher knowledge, attitudes, and overall KAP scores, consistent with findings from Jordan, Iraq, and urban Indonesia showing that female adolescents often exhibit greater health literacy and attentiveness to health-related issues [18,21,22]. In rural settings, these differences may additionally reflect gender-related variations in socialization, communication preferences, and exposure to health information. Educational interventions should therefore adopt gender-responsive approaches and engage male adolescents through activity-based and technology-driven programs. These findings highlight the importance of considering sociodemographic context when designing adolescent diabetes prevention programs, particularly within rural settings where access to health education and preventive resources may vary.

Students attending peri-urban schools and those in higher grades demonstrated greater knowledge and more positive attitudes toward T2D. These differences may reflect greater cognitive maturity, better access to information, and increased exposure to structured health education [17,21]. Longer school hours and higher academic achievement were also associated with healthier preventive practices. This finding suggests that greater academic engagement and self-discipline may support greater health awareness and behavioral regulation [32–33]. Together, these findings highlight schools as critical platforms for structured, evidence-based health promotion.

Participation in extracurricular activities such as sports, scouting (Pramuka), and student councils was associated with higher knowledge, attitude, and overall KAP scores. These activities may provide opportunities for peer interaction, leadership development, and informal learning that reinforce health awareness [28,34]. Integrating diabetes prevention messages into existing extracurricular programs and encouraging greater participation among students in rural areas may therefore improve the reach and sustainability of health promotion efforts.

Adolescents who were uncertain about their family’s diabetes history consistently demonstrated lower KAP scores across domains. This finding may reflect lower perceived susceptibility to T2D and limited family communication regarding diabetes risk. Encouraging communication between adolescents and families regarding diabetes and family health history may help improve awareness and motivation for preventive behaviors.

Exposure to diabetes-related information through social media, digital platforms, or school programs was also linked to higher KAP scores, highlighting the potential role of digital communication in supporting adolescent health literacy [16,21,22]. Leveraging social media and school-supported digital health campaigns may help expand the reach of diabetes education in resource-limited rural settings, provided that the content is accurate, engaging, and culturally relevant.

Interrelationships among KAP domains

Although knowledge and attitude scores were positively correlated with overall KAP scores, their relationships with preventive practices were weak. Similar findings have been reported in Jordan, Nepal, and Iraq [17,18,22]. These findings suggest that the traditional KAP framework in which knowledge and attitudes are expected to support healthy behaviors may not fully capture the complexity of adolescent preventive practices. Adolescent health behaviors are also influenced by psychosocial and environmental determinants, including peer influence, family norms, social support, and the increasing independence of adolescents in shaping their own health behaviors [34].

Integrating broader behavioral frameworks, such as the Health Belief Model and Social Cognitive Theory, may strengthen diabetes education by addressing motivational, social, and contextual influences alongside cognitive learning. From a Health Belief Model perspective, adolescents may possess some basic diabetes-related awareness yet still lack sufficient perceived susceptibility or cues to action to adopt preventive behaviors. Social Cognitive Theory further suggests that adolescent behaviors are shaped not only by knowledge, but also by peer modeling, family influences, social reinforcement, and self-efficacy. These frameworks therefore help explain why awareness and positive attitudes did not consistently translate into healthier preventive practices in this study.

Implications for practice and policy

These findings carry important practical and policy implications for diabetes prevention among adolescents in rural Indonesia. Schools are strategic settings for health promotion because of their broad reach and structured environments. School-based interventions should be tailored to the limited resources and sociocultural contexts of rural communities. Rather than relying solely on classroom-based instruction, diabetes prevention strategies may be more sustainable when integrated into existing school and community structures, including extracurricular activities, school health units (Usaha Kesehatan Sekolah/UKS), peer-led initiatives, and collaborations with primary health centers (Puskesmas) and community health cadres. Participatory approaches such as group discussions, peer mentoring, and activity-based learning may further improve student engagement and knowledge retention.

Given the increasing use of smartphones among adolescents, including those in rural areas, low-cost digital approaches such as digital health education programs, short educational videos, and social media campaigns may further expand access to diabetes-related information in remote communities. Investments in teacher training, school health infrastructure, and digital learning resources are also important to support long-term program sustainability. Policymakers should additionally address broader structural and environmental barriers, including challenges related to engaging in physical activity and the accessibility of tobacco products, which may undermine health promotion efforts in rural communities.

Strengths and limitations

This study contributes to the limited evidence on diabetes-related KAP among adolescents in rural Asia. Its large school-based sample and analysis of sociodemographic correlates strengthen the relevance of the findings for similar rural contexts. Furthermore, examining interrelationships among KAP domains provides additional insight into the relationship between awareness and behavior.

However, several limitations should be noted. The cross-sectional design precludes causal inference, and the use of self-reported data may have introduced social desirability and recall bias, particularly regarding family history of T2D and prior exposure to diabetes-related information. Selection bias may also have occurred because only students enrolled in school and present during data collection were included. In addition, the quantitative nature of the study may not have fully captured the complexity of adolescents’ beliefs or contextual influences on behavior. Finally, the practice domain focused primarily on physical activity, smoking, and weight monitoring, while other relevant behaviors such as dietary habits, screen time, and sleep patterns were not assessed and may also influence adolescents’ risk of T2D.

Conclusion

Rural Indonesian adolescents demonstrated limited knowledge and suboptimal preventive behaviors related to T2D despite relatively favorable attitudes toward prevention. Sociodemographic and school-related factors, particularly gender, academic performance, school location, and extracurricular participation, were associated with more favorable KAP outcomes. Longer school hours and higher academic achievement were also associated with healthier preventive practices. Weak correlations between preventive practices and the knowledge and attitude domains highlight a gap between diabetes-related awareness and preventive behaviors among adolescents. Addressing this gap requires school-based, peer-led, and after-school interventions, such as extracurricular activities, that integrate behavioral reinforcement into health education. Strengthening diabetes literacy and promoting healthy lifestyle behaviors during adolescence may help reduce early T2D risk and mitigate the long-term burden of diabetes in Indonesia and other low- and middle-income settings.

Supporting information

S1 File. Questionnaire in Indonesian language.

(DOCX)

pone.0352982.s001.docx (30.2KB, docx)
S2 File. Questionnaire in English language.

(DOCX)

pone.0352982.s002.docx (31.4KB, docx)
S3 File. Inclusivity in global research questionnaire.

(DOCX)

pone.0352982.s003.docx (69.5KB, docx)
S1 Checklist. STROBE Checklist.

(DOC)

pone.0352982.s004.doc (90.5KB, doc)
S1 Table. Results of the bivariate analyses.

(DOCX)

pone.0352982.s005.docx (22.6KB, docx)

Acknowledgments

We would like to express our sincere gratitude to Universitas Pahlawan Tuanku Tambusai, the students and alumni of the Faculty of Health Sciences who were involved in and supportive of this study, the provincial education department, and the participating schools for their support and cooperation.

Data Availability

All relevant data supporting the findings of this study are available within the paper, its Supporting information files, and the Open Science Framework (OSF) repository: https://osf.io/u8q9k/.

Funding Statement

The author(s) received no specific funding for this work.

References

  • 1.International Diabetes Federation. IDF Diabetes Atlas. 11 ed. Brussels: International Diabetes Federation; 2025. [cited 2025 August 21]. Available from: https://diabetesatlas.org [Google Scholar]
  • 2.Naghavi M, Abolhassani H, Abbasifard M, Abbasi J, Abd-Allah F, Abdelalim A, et al. Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021: a systematic analysis for the Global Burden of Disease Study 2021. Lancet. 2024;403(10440):2100–32. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Institute for Health Metrics and Evaluation. Indonesia. Seattle (WA): IHME; 2023. [cited 2025 June 15]. Available from: https://www.healthdata.org/research-analysis/health-by-location/profiles/indonesia [Google Scholar]
  • 4.Hidayat B, Ramadani RV, Rudijanto A, Soewondo P, Suastika K, Siu Ng JY. Direct medical cost of type 2 diabetes mellitus and its associated complications in Indonesia. Value Health Reg Issues. 2022;28:82–9. doi: 10.1016/j.vhri.2021.04.006 [DOI] [PubMed] [Google Scholar]
  • 5.Perng W, Conway R, Mayer-Davis E, Dabelea D. Youth-onset type 2 diabetes: the epidemiology of an awakening epidemic. Diabetes Care. 2023;46(3):490–9. doi: 10.2337/dci22-0046 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Xie J, Wang M, Long Z, Ning H, Li J, Cao Y, et al. Global burden of type 2 diabetes in adolescents and young adults, 1990-2019: systematic analysis of the Global Burden of Disease Study 2019. BMJ. 2022;379:e072385. doi: 10.1136/bmj-2022-072385 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 7.Kementerian Kesehatan Republik Indonesia. Indonesian Health Survey 2023. Jakarta: Kemenkes RI; 2023. [cited 2025 April 4]. Available from: https://drive.google.com/file/d/1NMZwTtFMamkmMe-H8OpZwan105kiSQtq/view [Google Scholar]
  • 8.Kusumawati N, Agritubella SM, Rosy A, Erlin F, Pijl H. Challenges in type 2 diabetes prevention among senior high school students: a qualitative study. Int J Community Based Nurs Midwifery. 2024;12(3):175–87. doi: 10.30476/IJCBNM.2024.101360.2413 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Faust AM, Auerbeck A, Lee AM, Kim I, Conroy DE. Passive sensing of smartphone use, physical activity and sedentary behavior among adolescents and young adults during the COVID-19 pandemic. J Behav Med. 2024;47(5):770–81. doi: 10.1007/s10865-024-00499-x [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Bozzola E, Barni S, Ficari A, Villani A. Physical activity in the COVID-19 era and its impact on adolescents’ well-being. Int J Environ Res Public Health. 2023;20(4):3275. doi: 10.3390/ijerph20043275 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 11.Liu Y, Sun X, Zhang E, Li H, Ge X, Hu F, et al. Association between types of screen time and weight status during the COVID-19 pandemic: a longitudinal study in children and adolescents. Nutrients. 2023;15(9):2055. doi: 10.3390/nu15092055 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12.Badan Pusat Statistik. Persentase rumah tangga yang memiliki/menguasai telepon seluler menurut provinsi dan klasifikasi daerah, 2022–2023. Jakarta: Badan Pusat Statistik; 2023. [cited 2025 April 18]. Available from: https://www.bps.go.id/id/statistics-table/2/MzkxIzI=/persentase-rumah-tangga-yang-memiliki-menguasai--telepon-seluler-menurut-provinsi-dan-klasifikasi-daerah.html [Google Scholar]
  • 13.Badan Pusat Statistik. Proporsi individu yang menggunakan internet menurut kelompok umur (persen), 2018–2019. Jakarta: Badan Pusat Statistik; 2023. [cited 2025 May 29]. Available from: https://www.bps.go.id/id/statistics-table/2/MTIyOCMy/proporsi-individu-yang-menggunakan-internet-menurut-kelompok-umur.html [Google Scholar]
  • 14.Potas N, Açıkalın ŞN, Erçetin ŞŞ, Koçtürk N, Neyişci N, Çevik MS, et al. Technology addiction of adolescents in the COVID-19 era: mediating effect of attitude on awareness and behavior. Curr Psychol. 2022;41(4):1687–703. doi: 10.1007/s12144-021-01470-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15.Wahidin M, Achadi A, Besral B, Kosen S, Nadjib M, Nurwahyuni A, et al. Projection of diabetes morbidity and mortality till 2045 in Indonesia based on risk factors and NCD prevention and control programs. Sci Rep. 2024;14(1):5424. doi: 10.1038/s41598-024-54563-2 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 16.Akter F, Rashid SMM, Alam N, Lipi N, Qayum MO, Nurunnahar M, et al. Knowledge, attitude and practice of diabetes among secondary school-going children in Bangladesh. Front Public Health. 2022;10:1047617. doi: 10.3389/fpubh.2022.1047617 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Sitaula D, Shrestha N, Timalsina S, Pokharel B, Sapkota S, Acharya S, et al. Knowledge, attitude and practice regarding diabetes and hypertension among school students of Nepal: a rural vs. urban study. PLoS One. 2022;17(8):e0270186. doi: 10.1371/journal.pone.0270186 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Elsahoryi NA, Odeh MM, Alsous M, Kastero DH, Al-Mughrabi LF, Darras SA. Adolescents with diabetes: exploring knowledge, attitude, and practice—a cross-sectional analytical study. Pharm Pract (Granada). 2024;22:014. doi: 10.18549/PharmPract.2024.4.3014 [DOI] [Google Scholar]
  • 19.Shilpashree YD, Nusrath A, Devegowda N. Knowledge of diabetes among rural high school children on Mandya. Int J Biochem Biophys. 2018;6. doi: 10.13189/ijbb.2018.060301 [DOI] [Google Scholar]
  • 20.K C S, Kaphle HP, Neupane N, Baral S. Internet use and its association with physical activity among adolescents in Beni Municipality, Myagdi, Nepal. PLoS One. 2024;19(5):e0302456. doi: 10.1371/journal.pone.0302456 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Pandit A, Sapkota B, Poudel N, Karki R, Poudel B, Lamichhane R. Evaluation of knowledge and awareness of diabetes in higher secondary level students of Kaski district: a cross-sectional study. PLoS One. 2025;20(2):e0313755. doi: 10.1371/journal.pone.0313755 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 22.Mosa AA, Abdulqadir HH, Khalid RC, Mustafa AA, Zaki HA, Yousif IR, et al. Diabetes mellitus awareness among students attending a public high school in Kurdistan Region of Iraq: a cross-sectional study. Ann Med Surg (Lond). 2025;87(3):1236–42. doi: 10.1097/MS9.0000000000003046 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 23.Dinas Kesehatan Provinsi Riau. Profil Kesehatan Provinsi Riau Tahun 2022. Pekanbaru: Dinas Kesehatan Provinsi Riau; 2022. [cited 2025 July 27]. Available from: https://dinkes.riau.go.id/sites/default/files/2023-11/Profil%20Kesehatan%20Provinsi%20Riau%202022.pdf [Google Scholar]
  • 24.Bujang MA. A step-by-step process on sample size determination for medical research. Malays J Med Sci. 2021;28(2):15–27. doi: 10.21315/mjms2021.28.2.2 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25.Chauvet G. Coupling methods for multistage sampling. Ann Stat. 2015;43:2848–506. doi: 10.1214/15-AOS1348 [DOI] [Google Scholar]
  • 26.Kaliyaperumal K. Guideline for conducting a knowledge, attitude and practice (KAP) study. AECS Illumination. 2004;4(1):7–9. [Google Scholar]
  • 27.Al-Hussaini M, Mustafa S. Adolescents’ knowledge and awareness of diabetes mellitus in Kuwait. Alex J Med. 2016;52:61–6. doi: 10.1016/j.ajme.2015.04.001 [DOI] [Google Scholar]
  • 28.Alhilali MY, Alhilaly YS, Alkalash S. Knowledge and attitude of school students about diabetes mellitus in the western region of Saudi Arabia. Cureus. 2023;15:e47514. doi: 10.7759/cureus.47514 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 29.Zeleke EA, Fikadu T, Bekele M, Sidamo NB, Temesgen Worsa K. Physical activity status among adolescents in Southern Ethiopia: a mixed methods study. PLoS One. 2023;18(11):e0293757. doi: 10.1371/journal.pone.0293757 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30.Yusuf RA, Mont DF, Lin W-H, Chen H-J. Adolescents’ physical activity and the association with perceived social support of parents and peers in Indonesia. Asia Pac J Public Health. 2021;33(4):388–95. doi: 10.1177/1010539521997255 [DOI] [PubMed] [Google Scholar]
  • 31.Rosilawati Y, Rafique Z, Sudiwijaya E. Tobacco use among in-school young adolescents in Indonesia: exploring availability, affordability, and accessibility. PLoS One. 2024;19(3):e0301291. doi: 10.1371/journal.pone.0301291 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 32.Arundell L, Hinkley T, Veitch J, Salmon J. Contribution of the after-school period to children’s daily participation in physical activity and sedentary behaviours. PLoS One. 2015;10(10):e0140132. doi: 10.1371/journal.pone.0140132 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 33.Shi Y, Qu S. The effect of cognitive ability on academic achievement: the mediating role of self-discipline and the moderating role of planning. Front Psychol. 2022;13:1014655. doi: 10.3389/fpsyg.2022.1014655 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 34.Ameneh PD, Mohtasham G, Sakineh R, Yadollah M, Ali R. School-based peer-led diabetes intervention among female adolescents: a cluster randomized trial. BMC Public Health. 2023;23(1):1170. doi: 10.1186/s12889-023-15430-3 [DOI] [PMC free article] [PubMed] [Google Scholar]

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Reviewer #1: No

Reviewer #2: No

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Reviewer #1: The manuscript addresses an important public health issue with a large and well-powered sample size.. The manuscript is really good. However, some recommendations are required:

The statistical analysis is comprehensive, but justification for using linear regression on non-normally distributed scores should be clarified.

The discussion could better elaborate on practical intervention models tailored to rural school settings.

Some tables (especially Table 5) are dense and may benefit from simplification for readability.

Minor English language editing and proofreading are recommended to improve clarity and flow.

Reviewer #2: Justify why linear regression is appropriate or or

consider generalized linear model or ordinal

regression

Include brief explanation of what effect size

represents in real terms and clarify whether

observed differences are meaningful in practice

Incomplete reporting requirements

data availability statement, funding statement,

competing interest declaration are missing.

Include all required sections to comply with

journal guidelines

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Reviewer #1: Yes: Nasser M Alorfi

Reviewer #2: Yes: ATUHAIRE PHIONAH

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Attachment

Submitted filename: PROS ONE REVIEW REPORT.pdf

pone.0352982.s006.pdf (29.6KB, pdf)
PLoS One. 2026 Jul 8;21(7):e0352982. doi: 10.1371/journal.pone.0352982.r002

Author response to Decision Letter 1


1 Jun 2026

Response to Reviewers and Editors

Manuscript title: Knowledge, attitudes, and practices regarding type 2 diabetes and associated factors among rural adolescents in Indonesia: a cross-sectional study

We sincerely thank the Editor and Reviewers for their insightful and constructive comments. We carefully revised the manuscript in response to all suggestions. Major revisions included clarification of statistical methods, expansion of ethical and reporting details, integration of behavioral frameworks, simplification of tables, addition of reporting statements and supporting files, and revision of language throughout the manuscript. All changes are reflected in the revised manuscript and supporting information.

EDITOR’S COMMENTS

Comment 1: Ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming

Response:

We reviewed the manuscript and supporting files to ensure full compliance with PLOS ONE style requirements, including manuscript formatting, table presentation, supporting information organization, and file naming conventions.

Formatting:

The manuscript text was revised to conform to PLOS ONE formatting requirements, including heading structure, paragraph formatting, and table presentation.

Table presentation:

We revised the tables according to the journal guidelines. All tables were reformatted according to PLOS ONE guidelines and included as editable tables within the manuscript: Table 1 on pages 13–15, Table 2 on pages 15–16, Table 3 on page 17, Table 4 on page 18, Table 5 on page 19, Table 6 on pages 22–24, and Table 7 on pages 24–25.

Supplementary material organization:

Supporting files were appropriately cited in the manuscript text, including S1 File (page 8, line 168), S2 File (page 8, line 169), S3 File (page 10, line 237), S4 Checklist (page 11, line 240), and S5 Table (page 19, line 355).

File naming conventions:

We also revised the supporting information file names on page 38, lines 751–755, as follows:

• S1 File. Questionnaire in Indonesian language.

• S2 File. Questionnaire in English language.

• S3 File. Inclusivity in Global Research Questionnaire.

• S4 Checklist. STROBE checklist.

• S5 Table. Results of the bivariate analyses.

In addition, because our study used a cross-sectional design, we completed and included the STROBE checklist (S4 Checklist. STROBE checklist), in accordance with the journal guidelines. The checklist is cited in the Methods section on pages 10–11, lines 237–240, under the subtitle “Inclusivity in Global Research and Reporting Guidelines.”

Comment 2: Please include a complete copy of PLOS’ questionnaire on inclusivity in global research in your revised manuscript

Response:

We have included a complete copy of the PLOS inclusivity in global research questionnaire in the revised manuscript submission, as requested (S3 File. Inclusivity in Global Research Questionnaire; listed in the Supporting Information section on page 38, line 753).

We also added a subsection on inclusivity in global research in the Methods section under a separate subtitle, in accordance with the journal guidelines, on page 10, lines 235–237. In accordance with the PLOS inclusivity in global research guidance, we also added the following sentence to the Ethical Considerations section on page 10, lines 216–218: “The study was conducted in accordance with the approved protocol, and no major deviations occurred during the study period.”

Comment 3: If the reviewer comments include a recommendation to cite specific previously published works, please review and evaluate these publications to determine whether they are relevant and should be cited. There is no requirement to cite these works unless the editor has indicated otherwise.

Response:

We did not receive reviewer recommendations to cite additional references; therefore, no citations were included specifically in response to this point. However, we added two additional references to support and accommodate the revisions made throughout the manuscript.

Comment 4: Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and include a citation and full reference for the retraction notice.

Response:

We reviewed the reference list to ensure that all citations were complete, accurate, and current. We did not identify any retracted articles among the references cited in the manuscript.

REVIEWER 1 COMMENTS

Comment 1: The statistical analysis is comprehensive, but justification for using linear regression on non-normally distributed scores should be clarified.

Response:

We appreciate the reviewer’s comment. The non-normal distribution of KAP scores was reported primarily because non-parametric tests were used in the bivariate analyses.

Although the KAP scores were non-normally distributed and bounded by minimum and maximum values, they were derived as summed composite scores with multiple possible values and were therefore treated as approximately continuous outcomes for the regression analyses. Importantly, multiple linear regression does not require the dependent variable itself to be normally distributed; rather, the assumptions primarily concern the distribution of residuals and overall model fit. Diagnostic assessments indicated acceptable model fit and that residual assumptions were adequately satisfied. In addition, robust standard errors were applied to address potential heteroskedasticity.

We have clarified this rationale and the associated diagnostic assessments in the Methods section of the revised manuscript (Pages 11–12, lines 248–278). We also clarified the scoring procedures for the knowledge, attitude, practice, and overall KAP domains in the Methods section (Pages 8–9).

Comment 2: The discussion could better elaborate on practical intervention models tailored to rural school settings.

Response:

We have expanded the Discussion section to further elaborate on practical and contextually appropriate intervention models for rural Indonesian school settings, including school-based health education, peer-led approaches, extracurricular activities, and behavior-focused preventive strategies that may be feasible in resource-limited environments (Discussion section, pages 23–30).

Comment 3: Some tables (especially Table 5) are dense and may benefit from simplification for readability.

Response:

We have simplified Table 5, which is now presented as Table 6, to improve readability and clarity of presentation. Specifically, redundant statistical details were minimized, and the table layout was streamlined while retaining the key findings necessary for interpretation (Pages 22–24). The rows for the constant and model fit statistics were removed, and the model fit information along with other relevant notes are now presented in the table footnote (Page 24, lines 420–421).

Comment 4: Minor English language editing and proofreading are recommended to improve clarity and flow.

Response:

We revised the manuscript to improve clarity, readability, and overall flow. Additional English language editing and proofreading were conducted throughout the manuscript, including simplification of long sentences, refinement of grammar, and improvement of transitions between sections (Abstract, Introduction, Methods, and Discussion sections).

REVIEWER 2 COMMENTS

Comment 1: Abstract is too dense and slightly inconsistent [Overloaded with too many numbers for statistics for readability].

Response

We revised the abstract, particularly the Results section, to improve clarity and readability by reducing excessive statistical detail and removing less essential regression coefficients and p-values. The revised abstract now focuses more clearly on the main findings, key associations, and overall study implications while maintaining consistency with the full manuscript and ensuring that the abstract remains within the journal’s word limit (Page 2, lines 38–45).

Comment 2. Interpretation of knowledge scores [manuscript reports a median knowledge score of 5/18 but does not provide framework for interpreting the value.

Response

Thank you for this valuable feedback. Because median (IQR) values alone do not provide standardized interpretation of KAP levels, we incorporated modified Bloom’s cutoff criteria to classify KAP scores into low, moderate, and high categories. This approach was used to improve interpretability and provide clearer context for readers. We have clarified this classification approach in the Methods section (Page 11, lines 248–252) and incorporated the categorized findings into the Results section (Pages 18–19, lines 339–351, Table 5. Distribution of knowledge, attitude, practice and overall KAP).

Comment 3. Limited scope of practice domain [you only included physical activity, smoking, and weight monitoring leaving out key behaviors such as diet, screen time.

Response

We acknowledge that the practice domain did not include several relevant diabetes-related behaviors, such as dietary habits, screen time, and sleep patterns. To address this concern, we have added this point to the limitations section of the manuscript and clarified that the practice domain focused primarily on physical activity, smoking, and weight monitoring (Pages 31–32, lines 591–594).

Comment 4. Use of linear regression with non-normal data[You used multiple linear regression, but KAP scores are ordinal/bounded

Response

We appreciate the reviewer’s comment. The non-normal distribution of KAP scores was reported primarily because non-parametric tests were used in the bivariate analyses.

Although the KAP scores were non-normally distributed and bounded by minimum and maximum values, they were derived as summed composite scores with multiple possible values and were therefore treated as approximately continuous outcomes for the regression analyses. Importantly, multiple linear regression does not require the dependent variable itself to be normally distributed; rather, the assumptions primarily concern the distribution of residuals and overall model fit. Diagnostic assessments indicated acceptable model fit and that residual assumptions were adequately satisfied. In addition, robust standard errors were applied to address potential heteroskedasticity.

We have clarified this rationale and the associated diagnostic assessments in the Methods section of the revised manuscript (Pages 11–12, lines 248–268). We also clarified the scoring procedures for the knowledge, attitude, practice, and overall KAP domains in the Methods section (Pages 8–9)

Comment 5. Interpretation of effect size[B values are presented without practical interpretation]

Response

We revised the Results section, particularly the multivariable analysis of sociodemographic factors, to provide clearer interpretations of the regression coefficients. Instead of using only general associative language, we incorporated more specific interpretations, such as indicating higher or lower KAP scores in relation to key factors, alongside the reported statistical significance. Specifically, we clarified the approximate differences in KAP scores associated with important sociodemographic characteristics to help readers better understand the practical meaning of the observed effect sizes. We also used cautious and non-causal language throughout to avoid overstating the practical importance of the associations (Pages 20–22, lines 365–409). In addition, explanations regarding the practical interpretation of effect sizes and whether the observed differences may be meaningful in practice were added on page 22 (lines 410–415).

Comment 6. Causal language in cross sectional study[ some statements imply causality which is not appropriate for cross sectional study]----longer school hours improve practice.

Response

We carefully revised the manuscript to avoid causal language that may not be appropriate for a cross-sectional study design. Statements implying causality were replaced with associative terms such as “associated with,” “linked to,” or “may reflect,” and these revisions were applied consistently throughout the manuscript, including the Results, Discussion, and Conclusion sections.

Comment 7. Incomplete reporting requirements data availability statement, funding statement, competing interest declaration are missing.

Response

In the revised manuscript, we added a Data Availability Statement, Funding Statement, and Competing Interests Statement in accordance with PLOS ONE reporting requirements. The Data Availability Statement includes access to the study data through the Open Science Framework (OSF) repository (Page 33, lines 614–635). In addition, we included a completed STROBE checklist to improve reporting transparency and completeness (Pages 10–11, lines 237–240).

Comment 8. Ethical considerations[Data handling and confidentiality measures are not detailed

Response

We revised the Ethics section to provide clearer details regarding data handling and confidentiality procedures. Specifically, we clarified that questionnaires were anonymous, no identifying information was collected, completed questionnaires were coded and stored securely in a locked cabinet accessible only to the research team, and data were analyzed in aggregate form to maintain participant confidentiality. We also added information regarding the data retention period (Page 10, lines 228–233).

Comment 9. Language and grammar[some sentences are overly long and may reduce clarity. Minor grammatical errors and typo issues are present]

Response

We carefully revised the manuscript to improve readability and clarity. Several long and complex sentences were simplified, and sentence structures were refined throughout the manuscript to improve flow, reduce redundancy, and enhance comprehension while preserving the original meaning.

Comment 10. Repetition [Some redundancy exists between introduction and discussion sections]

Response

We carefully revised the manuscript to reduce redundancy between the Introduction and Discussion sections. Background information that overlapped with the Discussion was condensed or removed, and several sentences were simplified to improve readability and flow. The Introduction now focuses more clearly on the study rationale and research gaps, while the Discussion emphasizes interpretation of findings, comparison with previous studies, and implications for practice and policy.

Comment 11. Theoretical framework[there is a brief reference on behavioral models without sufficient integration]

Response

In the revised Discussion section, we expanded the theoretical interpretation of the observed knowledge–practice gap by further integrating relevant behavioral frameworks, particularly the Health Belief Model and Social Cognitive Theory. Specifically, we elaborated on how limited perceived susceptibility, insufficient cues to action, peer modeling, family influences, social reinforcement, and self-efficacy may help explain why awareness and positive attitudes did not consistently translate into healthier preventive practices among adolescents. These additions strengthen the interpretation of our findings and support the need for behaviorally informed school-based interventions (Page 30, lines 546–554).

Attachment

Submitted filename: Response to Reviewers.docx

pone.0352982.s008.docx (30.1KB, docx)

Decision Letter 1

Cho Lee Wong, Cho Lee Wong

18 Jun 2026

Knowledge, attitudes, and practices regarding type 2 diabetes and associated factors among rural adolescents in Indonesia: a cross-sectional study

PONE-D-25-61411R1

Dear Dr. Kusumawati,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

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Kind regards,

Cho Lee Wong, PhD

Academic Editor

PLOS One

Additional Editor Comments (optional):

Reviewers' comments:

Acceptance letter

Cho Lee Wong, Cho Lee Wong

PONE-D-25-61411R1

PLOS One

Dear Dr. Kusumawati,

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS One. Congratulations! Your manuscript is now being handed over to our production team.

At this stage, our production department will prepare your paper for publication. This includes ensuring the following:

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Academic Editor

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Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 File. Questionnaire in Indonesian language.

    (DOCX)

    pone.0352982.s001.docx (30.2KB, docx)
    S2 File. Questionnaire in English language.

    (DOCX)

    pone.0352982.s002.docx (31.4KB, docx)
    S3 File. Inclusivity in global research questionnaire.

    (DOCX)

    pone.0352982.s003.docx (69.5KB, docx)
    S1 Checklist. STROBE Checklist.

    (DOC)

    pone.0352982.s004.doc (90.5KB, doc)
    S1 Table. Results of the bivariate analyses.

    (DOCX)

    pone.0352982.s005.docx (22.6KB, docx)
    Attachment

    Submitted filename: PROS ONE REVIEW REPORT.pdf

    pone.0352982.s006.pdf (29.6KB, pdf)
    Attachment

    Submitted filename: Response to Reviewers.docx

    pone.0352982.s008.docx (30.1KB, docx)

    Data Availability Statement

    All relevant data supporting the findings of this study are available within the paper, its Supporting information files, and the Open Science Framework (OSF) repository: https://osf.io/u8q9k/.


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