NEUROSCIENCE. For the article “A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis,” by Ngan Vo, Matthew E. Klein, Olga Varlamova, David M. Keller, Tadashi Yamamoto, Richard H. Goodman, and Soren Impey, which appeared in issue 45, November 8, 2005, of Proc. Natl. Acad. Sci. USA (102, 16426–16431; first published October 31, 2005; 10.1073/pnas.0508448102), the authors note that in Fig. 4B, the solid and shaded legend boxes for miR132 and miR1-1 were transposed. The corrected figure and its legend appear below.
Fig. 4.
Expression of miR132 induces neurite sprouting. (A) Neonatal cortical neurons were transfected with a GFP reporter (green) and cotransfected with vector control, or expression constructs for premiR1-1 or premiR132. Cells were immunostained for the neuronal marker MAP2 (red). (B) Neurons were transfected as in A and analyzed morphometrically. The histogram depicts the distribution of neurons plotted as bins of neurites. The distributions were statistically distinct (P < 0.01; Kruskal–Wallis). (Inset) The average total neurite length (TNL) of miR1-1 (n = 109) and miR132 (n = 137) transfected neurons from four independent experiments. *, P < 0.01 for miR132 vs. miR1-1 (Student's t test).