Correction to: Scientific Reports 10.1038/s41598-025-13288-6, published online 04 August 2025
In the original version of this Article the captions of Figures 2, 3, 4 and 5 were interchanged.
The caption of Figure 2 was incorrectly given as:
Imaging mass spectroscopy reveals a unique lipid signature in positive modes. Positive MALDI-TOF images of mouse brain sections in each row display lipid signatures as indicated at a specific m/z value. The mass spectrum of individual groups of animals, Sham Vs TBI, is shown in sequence. Each image reveals the spatial distribution of distinct lipid molecular ions, utilizing a color scheme to denote the relative abundance of these specific lipids across various X-Y coordinates within the sample. The last panel to the right indicates the intensity of each m/z among the groups.
now reads:
Increase in calcium levels in superficial layers of the somatosensory cortex triggered by the airblast TBI. (A-B) Contrast normalized images of in vivo GCaMP6f signal before and t = 5 min after TBI, respectively, from a representative mouse. The gray value’s standard deviation (σ) was measured within the yellow ROI. Measurements excluded regions where vasculature occluded GCaMP6f fluorescence. (C) Measurements from 4 trials show statistically significant changes in the GCaMP6f signal after TBI (p > 0.05 for t = 5, 6, 7, 8, 9 min; not significant at t = 10 min).
The caption of Figure 3 was incorrectly given as:
Increase in calcium levels in superficial layers of the somatosensory cortex triggered by the airblast TBI. (A-B) Contrast normalized images of in vivo GCaMP6f signal before and t = 5 min after TBI, respectively, from a representative mouse. The gray value’s standard deviation (σ) was measured within the yellow ROI. Measurements excluded regions where vasculature occluded GCaMP6f fluorescence. (C) Measurements from 4 trials show statistically significant changes in the GCaMP6f signal after TBI (p > 0.05 for t = 5, 6, 7, 8, 9 min; not significant at t = 10 min).
now reads:
Immunohistochemical evidence of cellular changes after TBI. (A) Individual astrocytes labeled with GFAP showed increased immunoreactivity. (B) Mean fluorescent intensity was measured per field of view. (C) Immunohistology of S100B marker in astrocytic cell bodies, (E) a decreased S100B localization was noted in all three TBI groups. (D) NeuN localization in mature neurons tends to have uniform localization of the antigen throughout the nucleus (normal cell); however, after TBI, this neuronal marker segregates to the nuclear membrane (faint cells), as shown by yellow arrows. (E, F) Faint cells in a field of view were significantly increased in the injured areas within 5 min of injury.
The caption of Figure 4 was incorrectly given as:
Immunohistochemical evidence of cellular changes after TBI. (A) Individual astrocytes labeled with GFAP showed increased immunoreactivity. (B) Mean fluorescent intensity was measured per field of view. (C) Immunohistology of S100B marker in astrocytic cell bodies, (E) a decreased S100B localization was noted in all three TBI groups. (D) NeuN localization in mature neurons tends to have uniform localization of the antigen throughout the nucleus (normal cell); however, after TBI, this neuronal marker segregates to the nuclear membrane (faint cells), as shown by yellow arrows. (E, F) Faint cells in a field of view were significantly increased in the injured areas within 5 min of injury.
now reads:
The molecular signaling profile of airblast TBI was comprehensively captured by phosphoproteomics analysis. (A) Volcano plot showing the magnitude and significance of differential phosphopeptide abundance between sham and 15 psi exposed somatosensory cortex at 5 min post-exposure. Significant protein phosphorylation patterns are encircled in green. (B) The degree of phosphorylation and dephosphorylation for each identified protein is indicated in fold change. Red bars represent phosphorylation, while green represents dephosphorylation. (C) STRING analysis reveals intuitive bioinformatics visualization of the connectome between different phosphorylation patterns identified after the 15 psi blast Vs. Sham group. The network generated by STRING omitted the isolated genes; each node’s color is irrelevant, but the lines connecting each node have significance. Blue lines indicate the interactions in the database, whereas pink lines indicate the interaction was experimentally proven. (D) Proteins are sorted based on biological processes using Gene Ontology (GO) enrichment analysis, which is altered immediately in an airblast TBI. (E) Serine residues were prone to most phosphorylation changes, followed by threonine.
The caption of Figure 5 was incorrectly given as:
The molecular signaling profile of airblast TBI was comprehensively captured by phosphoproteomics analysis. (A) Volcano plot showing the magnitude and significance of differential phosphopeptide abundance between sham and 15 psi exposed somatosensory cortex at 5 min post-exposure. Significant protein phosphorylation patterns are encircled in green. (B) The degree of phosphorylation and dephosphorylation for each identified protein is indicated in fold change. Red bars represent phosphorylation, while green represents dephosphorylation. (C) STRING analysis reveals intuitive bioinformatics visualization of the connectome between different phosphorylation patterns identified after the 15 psi blast Vs. Sham group. The network generated by STRING omitted the isolated genes; each node’s color is irrelevant, but the lines connecting each node have significance. Blue lines indicate the interactions in the database, whereas pink lines indicate the interaction was experimentally proven. (D) Proteins are sorted based on biological processes using Gene Ontology (GO) enrichment analysis, which is altered immediately in an airblast TBI. (E) Serine residues were prone to most phosphorylation changes, followed by threonine.
now reads:
Imaging mass spectroscopy reveals a unique lipid signature in positive modes. Positive MALDI-TOF images of mouse brain sections in each row display lipid signatures as indicated at a specific m/z value. The mass spectrum of individual groups of animals, Sham Vs TBI, is shown in sequence. Each image reveals the spatial distribution of distinct lipid molecular ions, utilizing a color scheme to denote the relative abundance of these specific lipids across various X-Y coordinates within the sample. The last panel to the right indicates the intensity of each m/z among the groups.
The original Article has been corrected.