Abstract
OBJECTIVE: To determine the effect of lead contamination around a lead-reclamation plant on the blood lead levels of children and pregnant women living in the area. DESIGN: Prevalence study. SETTING: Residents living 150 m or less (high-exposure area), 151 to 400 m (intermediate-exposure area) or 401 to 800 m (low-exposure area) southeast from the plant. PARTICIPANTS: All children aged 10 years or less and all pregnant women living in the designated area. OUTCOME MEASURES: Correlation of venous blood lead levels with soil lead concentrations in the areas in which the subjects lived and with sociodemographic and behavioural factors. MAIN RESULTS: Of the estimated 57 pregnant women 38 (67%) participated: 20 were in the high-exposure area and 18 in the other two areas; their geometric mean blood lead levels were low (0.15 and 0.13 mumol/L respectively). Of the 625 eligible children 510 (82%) participated: 169 were in the high-exposure area, 179 in the intermediate-exposure area and 162 in the low-exposure area; their geometric mean lead levels were 0.43, 0.30 and 0.26 mumol/L respectively. Within each age group children in the high-exposure area had the highest levels. The mean levels for children aged 6 months to 5 years were 0.49, 0.35 and 0.28 mumol/L in the three areas respectively. Within each exposure group children aged 1 to 2 years had the highest levels. No potential confounding variables could explain the relation between blood lead level and soil lead concentration. CONCLUSIONS: The pregnant women's blood lead levels did not seem to be affected by exposure level, but the children's levels were primarily related to the soil lead concentration.
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Selected References
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- Baghurst P. A., McMichael A. J., Vimpani G. V., Robertson E. F., Clark P. D., Wigg N. R. Determinants of blood lead concentrations of pregnant women living in Port Pirie and surrounding areas. Med J Aust. 1987 Jan 19;146(2):69–73. doi: 10.5694/j.1326-5377.1987.tb136265.x. [DOI] [PubMed] [Google Scholar]
- Brockhaus A., Collet W., Dolgner R., Engelke R., Ewers U., Freier I., Jermann E., Krämer U., Manojlovic N., Turfeld M. Exposure to lead and cadmium of children living in different areas of north-west Germany: results of biological monitoring studies 1982-1986. Int Arch Occup Environ Health. 1988;60(3):211–222. doi: 10.1007/BF00378699. [DOI] [PubMed] [Google Scholar]
- Brunekreef B., Noy D., Biersteker K., Boleij J. Blood lead levels of Dutch city children and their relationship to lead in the environment. J Air Pollut Control Assoc. 1983 Sep;33(9):872–876. doi: 10.1080/00022470.1983.10465665. [DOI] [PubMed] [Google Scholar]
- Duggan M. J. Contribution of lead in dust to children's blood lead. Environ Health Perspect. 1983 Apr;50:371–381. doi: 10.1289/ehp.8350371. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Duggan M. J., Inskip M. J. Childhood exposure to lead in surface dust and soil: a community health problem. Public Health Rev. 1985;13(1-2):1–54. [PubMed] [Google Scholar]
- Elwood P. C. The sources of lead in blood: a critical review. Sci Total Environ. 1986 Jun;52(1-2):1–23. doi: 10.1016/0048-9697(86)90101-4. [DOI] [PubMed] [Google Scholar]
- Fergusson J. E. Lead: petrol lead in the environment and its contribution to human blood lead levels. Sci Total Environ. 1986 Apr;50:1–54. doi: 10.1016/0048-9697(86)90350-5. [DOI] [PubMed] [Google Scholar]
- Fernandez F. J. Micromethod for lead determination in whole blood by atomic absorption, with use of the graphite furnace. Clin Chem. 1975 Apr;21(4):558–561. [PubMed] [Google Scholar]
- Madhavan S., Rosenman K. D., Shehata T. Lead in soil: recommended maximum permissible levels. Environ Res. 1989 Jun;49(1):136–142. doi: 10.1016/s0013-9351(89)80028-3. [DOI] [PubMed] [Google Scholar]
- Mahaffey K. R., Annest J. L., Roberts J., Murphy R. S. National estimates of blood lead levels: United States, 1976-1980: association with selected demographic and socioeconomic factors. N Engl J Med. 1982 Sep 2;307(10):573–579. doi: 10.1056/NEJM198209023071001. [DOI] [PubMed] [Google Scholar]
- Millar I. B. Monitoring of lead in the environment. J Epidemiol Community Health. 1978 Jun;32(2):111–116. doi: 10.1136/jech.32.2.111. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Needleman H. L. The persistent threat of lead: medical and sociological issues. Curr Probl Pediatr. 1988 Dec;18(12):697–744. doi: 10.1016/0045-9380(88)90004-7. [DOI] [PubMed] [Google Scholar]
- O'Heany J., Kusiak R., Duncan C. E., Smith J. F., Smith L. F., Spielberg L. Blood lead and associated risk factors in Ontario children. Sci Total Environ. 1988 Jun 1;71(3):477–483. doi: 10.1016/0048-9697(88)90221-5. [DOI] [PubMed] [Google Scholar]
- Quinn M. J., Delves H. T. UK blood lead monitoring programme 1984-1987: results for 1985. Hum Toxicol. 1988 Mar;7(2):105–123. doi: 10.1177/096032718800700202. [DOI] [PubMed] [Google Scholar]
- Rabinowitz M., Leviton A., Needleman H., Bellinger D., Waternaux C. Environmental correlates of infant blood lead levels in Boston. Environ Res. 1985 Oct;38(1):96–107. doi: 10.1016/0013-9351(85)90075-1. [DOI] [PubMed] [Google Scholar]
- Schilling R. J., Bain R. P. Prediction of children's blood lead levels on the basis of household-specific soil lead levels. Am J Epidemiol. 1988 Jul;128(1):197–205. doi: 10.1093/oxfordjournals.aje.a114941. [DOI] [PubMed] [Google Scholar]
- Schmitt N., Philion J. J., Larsen A. A., Harnadek M., Lynch A. J. Surface soil as a potential source of lead exposure for young children. Can Med Assoc J. 1979 Dec 8;121(11):1474–1478. [PMC free article] [PubMed] [Google Scholar]
- Skerfving S., Schütz A., Ranstam J. Decreasing lead exposure in Swedish children, 1978-84. Sci Total Environ. 1986 Dec 31;58(3):225–229. doi: 10.1016/0048-9697(86)90201-9. [DOI] [PubMed] [Google Scholar]
- Tenenbein M. Does lead poisoning occur in Canadian children? CMAJ. 1990 Jan 1;142(1):40–41. [PMC free article] [PubMed] [Google Scholar]
- Zarembski P. M., Griffiths P. D., Walker J., Goodall H. B. Lead in neonates and mothers. Clin Chim Acta. 1983 Oct 31;134(1-2):35–49. doi: 10.1016/0009-8981(83)90182-1. [DOI] [PubMed] [Google Scholar]
