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. 2026 Jul 3;15(13):1064. doi: 10.3390/biology15131064

Correction: Gurbuz Can et al. Altered Hippocampal Clock Gene Regulation Is Associated with Circadian Dysregulation of Oxidative Imbalance, Neuroinflammation, and Histopathological Damage After Pinealectomy. Biology 2026, 15, 655

Venhar Gurbuz Can 1,*, Mehmet Demir 2, Tansu Kusat 3, Feyza Basak 3
PMCID: PMC13359587  PMID: 42450642

Error in Figure

In the original publication [1], there was a mistake in Figure 4 as published. During the final revision process, a requested modification to Figure 4 was inadvertently not implemented in the published version of the article. The lower graph panel was inadvertently replaced with TNF-α and melatonin graphs. The correct lower panel should display the H-score analyses of caspase-3 and GFAP, consistent with the immunohistochemical findings and the values reported in the original figure legend. There is no error in the figure legend or elsewhere in the manuscript; the issue is limited solely to Figure 4. Importantly, this correction does not affect the results, statistical analyses, interpretation, or conclusions of the article. The corrected Figure 4 appears below. The authors state that the scientific conclusions are unaffected. This correction was approved by the Academic Editor. The original publication has also been updated.

Figure 4.

Figure 4

Immunohistochemical staining of caspase-3 and GFAP in hippocampal tissue of Control, Sham, and PNX groups, along with their corresponding H-score analyses. Arrowheads indicate cells presenting positive immunoreactivity. Data are expressed as mean ± SD (n = 10), and differences were considered statistically significant at p < 0.05. For caspase-3, the PNX group (83.413 ± 13.536) showed a significant increase compared with the Control (21.134 ± 10.345) and Sham (36.675 ± 11.463) groups (p < 0.05). Similarly, for GFAP, the PNX group (212.435 ± 17.535) was significantly higher than the Control (120.436 ± 15.753) and Sham (136.684 ± 13.546) groups (p < 0.05). No statistically significant differences were observed between the Control and Sham groups for either caspase-3 or GFAP H-scores (p > 0.05).

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Reference

  • 1.Gurbuz Can V., Demir M., Kusat T., Basak F. Altered Hippocampal Clock Gene Regulation Is Associated with Circadian Dysregulation of Oxidative Imbalance, Neuroinflammation, and Histopathological Damage After Pinealectomy. Biology. 2026;15:655. doi: 10.3390/biology15080655. [DOI] [PMC free article] [PubMed] [Google Scholar]

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