Abstract
By providing free medications to those who are uninsured and who have low income, organizations like NC MedAssist are able alleviate this barrier for thousands of North Carolinians each year. This article will describe the history and benefits of NC MedAssist.
Keywords: safety net, north carolina, NC MedAssist, pharmacy, mobile free pharmacy, UNC Charlotte, National Association of Free and Charitable Clinics
History
It is well known that paying for medications can be a barrier to adherence for many people.1,2 Alleviating this barrier can lead to better health care outcomes by improving the medical management of many conditions, including heart disease, diabetes, and asthma.3,4 In 1997, the Mecklenburg Medical Society Alliance in North Carolina started MedAssist of Mecklenburg as a way to serve senior adults in the county who were uninsured or had low incomes. The program was expanded in 2005 to include all adults in the county. In 2009, the Free Pharmacy Program (FFP) was expanded to cover all eligible North Carolina residents and the name was changed to NC MedAssist to portray this shift.5
NC MedAssist programs were expanded to provide over the counter (OTC) medications in 2012. Originally, the OTC Program was only provided in Charlotte; however, in 2014 the organization began providing OTC medications across the state through the Mobile Free Pharmacy Program (MFP). Additionally, the OTC Free Store opened in Charlotte in 2018 as a way to access OTC medications in person and was staffed by members of a new Transitional Jobs Program. With the onset of the COVID-19 pandemic in 2020, NC MedAssist began offering individuals the opportunity to pre-order OTC items online, to be dispensed at the free OTC Store and at MFP events. NC MedAssist’s 2022 annual report provides a snapshot of the programs and services offered to provide medications to those to those in need in North Carolina.6
Background
The mission of NC MedAssist is to “dispense opportunities through improved health”.7 This mission began with the understanding that medication adherence can lead to better health outcomes and reduced medical costs, as noted in Sokol’s seminal 2005 study.8 Since then, many other publications have demonstrated this relationship.3,4,8–15 One study conducted by Allaire and colleagues with Dispensary of Hope, a nonprofit distributor of free medications, found that medication adherence decreased inpatient hospitalization stays and per-person annual costs for one of its associated health care systems.15 These results were significant for patients with a higher number of comorbidities, demonstrating the importance of ensuring medication adherence, especially in those with multiple disease processes.15
For those who are uninsured or have low incomes, spending money on medications may not be a feasible option. The “free pharmacy” model, such as the one utilized by NC MedAssist, covers up-front costs of medications to avoid higher long-term costs of care as a result of non-adherence. Lloyd and colleagues (2019) estimated a savings of over $13 billion for Medicare if just 25% of their non-adherent clients became adherent to the medical course of treatment.10 The cost of the medications to treat or prevent medical complications would be far less than the cost of care for untreated conditions. It is well known that health insurance programs help to cover some of the costs of medication therapy for many individuals. North Carolina’s decision to expand Medicaid will decrease the number of uninsured in North Carolina by approximately 600,000.16 However, this expansion only covers those who are at 138% of the Federal Poverty level or less.17 There will still be a need for free pharmacy programs like NC MedAssist to provide services to those who do not qualify under Medicaid expansion or other health insurance programs.
The Role of NC MedAssist
Through funding received from numerous sources including grants, federal support, and individual/corporate donors, NC MedAssist provides free medications to eligible participants across North Carolina. In 2022, this resulted in an estimated $125 million in economic benefit to the state.6 While the number of patients served by NC MedAssist has steadily increased over the years, there were slight decreases after the start of the COVID-19 pandemic (Figure 1). This decline was also seen at other charitable clinics across the state as a result of the pandemic.18,19
Figure 1. Free Pharmacy Program Patients Serveda.

Abbreviation. FPP, Free Pharmacy Program
aData obtained from NC MedAssist
Eligibility for NC MedAssist includes uninsured North Carolina residents who are at or below 300% of the Federal Poverty Level.7 Once eligibility has been established, prescriptions are filled from NC MedAssist’s extensive formulary for conditions such as diabetes, heart failure, depression, and many other disease processes.20 Through the Free Pharmacy Program, postal delivery of prescription medications ensures timely access to needed therapies. Furthermore, OTC medications are available through the NC MedAssist store or through MFP events.21 Providing medications such as acetaminophen or ibuprofen to those who could not otherwise afford them may help to reduce emergency or primary care visits. These products are usually received from donors and area organizations.
Since the organization’s inception, NC MedAssist has provided an estimated 375,000 North Carolina residents with free medication via the OTC and FPP programs. In 2022, 15,748 patients received medications from the free pharmacy program, and 52,483 received OTC medications. A total of 68,201 individuals/families were served across the state in 20226 (2023 data are still pending as of this writing) (Figure 2). Patient referrals come from a variety of sources. Nearly 70% of patient referrals to NC MedAssist come from Partners of Hope, a network of over 100 clinics or safety-net organizations located throughout the state of North Carolina addressing gaps in care or social determinants of health.
Figure 2. Total Patients Serveda.

Abbreviation. FPP, Free Pharmacy Program; MFP, Mobile Free Pharmacy; Store, OTC Store; OTC, Over the Counter
aData obtained from NC MedAssist
Conclusion
The growth and success of NC MedAssist could not have been possible without the financial support from grants and donors, volunteer assistance, and partnership organizations (Figure 3).6 Continued support is needed for current programs, as well as new services like the tobacco cessation program. More research is needed to show the impact of a free pharmacy program on health care cost avoidance and patient health outcomes.3,4,15 As the only free pharmacy program in North Carolina, NC MedAssist provides essential services and acutely needed medications to thousands of people across the state each year.
Figure 3. Average Wholesale Pricea.

Abbreviation. AWP, Average Wholesale Price; BULK, Bulk replenishment from pharmaceutical companies; PAP, Patient Assistant Programs for individual pharmaceutical applications
aData obtained from NCMedAssist
Acknowledgments
The authors have no conflicts of interest to declare. All co-authors have seen and agree with the contents of the manuscript, and there is no financial interest to report.
References
- 1.8 reasons patients don’t take their medications. [2023-10-8]. https://www.ama-assn.org/delivering-care/patient-support-advocacy/8-reasons-patients-dont-take-their-medications Accessed October 8, 2023.
- 2.Teetzman J. MedAssist CARES expands access to prescription drugs for North Carolinians. [2023-10-1]. https://medassist.org/wp-content/uploads/2020/12/PR-CARES-Campaign.jpg
- 3.Medication adherence leads to lower health care use and costs despite increased drug spending. Roebuck M. Christopher, Liberman Joshua N., Gemmill-Toyama Marin, Brennan Troyen A. Jan;2011 Health Affairs (Millwood) 30(1):91–99. doi: 10.1377/hlthaff.2009.1087. https://doi.org/10.1377/hlthaff.2009.1087 [DOI] [PubMed] [Google Scholar]
- 4.Impact of medication adherence on health services utilization in Medicaid. Roebuck Mark C., Kaestner Robert J., Dougherty Julia S. Mar;2018 Med Care. 56(3):266–273. doi: 10.1097/mlr.0000000000000870. https://doi.org/10.1097/mlr.0000000000000870 [DOI] [PubMed] [Google Scholar]
- 5.NC MedAssist: Dispensing Hope for 25 years. [2023-10-1]. https://medassist.org/25years/
- 6.2022 Fiscal Year Annual Report. [2023-10-1]. https://medassist.org/wp-content/uploads/2022/11/MedAssist2022FY-FINAL.pdf
- 7.About Us: Our Vision. [2023-10-1]. https://medassist.org/about-us/
- 8.Impact of medication adherence on hospitalization risk and healthcare cost. Sokol Michael C., McGuigan Kimberly A., Verbrugge Robert R., Epstein Robert S. Jun;2005 Med Care. 43(6):521–530. doi: 10.1097/01.mlr.0000163641.86870.af. https://doi.org/10.1097/01.mlr.0000163641.86870.af [DOI] [PubMed] [Google Scholar]
- 9.Assessing the impact of medication adherence on long-term cardiovascular outcomes. Bansilal Sameer, Castellano Jose Maria, Garrido Ester, Wei Henry G., Freeman Allison, Spettell Claire, Garcia-Alonso Fernando, Lizano Irene, Arnold Renee J.G., Rajda Jay, Steinberg Gregory, Fuster Valentin. Aug;2016 Journal of the American College of Cardiology. 68(8):789–801. doi: 10.1016/j.jacc.2016.06.005. https://doi.org/10.1016/j.jacc.2016.06.005 [DOI] [PubMed] [Google Scholar]
- 10.How much does medication nonadherence cost the Medicare fee-for-service program? Lloyd Jennifer T., Maresh Sha, Powers Christopher A., Shrank William H., Alley Dawn E. Mar;2019 Med Care. 57(3):218–224. doi: 10.1097/mlr.0000000000001067. https://doi.org/10.1097/mlr.0000000000001067 [DOI] [PubMed] [Google Scholar]
- 11.Cost-effectiveness analysis of an adherence-promotion intervention for children with leukemia: a Markov Model-based simulation. McGrady Meghan E, Eckman Mark H, O’Brien Maureen M, Pai Ahna L H. May 15;2018 Journal of Pediatric Psychology. 43(7):758–768. doi: 10.1093/jpepsy/jsy022. https://doi.org/10.1093/jpepsy/jsy022 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 12.Impact and continued relevance of medication adherence measurement. Shirley Ben, Castora-Binkley Melissa, Hines Lisa. Aug 1;2022 Population Health Management. 25(4):575–578. doi: 10.1089/pop.2022.0022. https://doi.org/10.1089/pop.2022.0022 [DOI] [PubMed] [Google Scholar]
- 13.Medication adherence: understanding the issues and finding solutions. While Alison. Oct 2;2020 British Journal of Community Nursing. 25(10):474–479. doi: 10.12968/bjcn.2020.25.10.474. https://doi.org/10.12968/bjcn.2020.25.10.474 [DOI] [PubMed] [Google Scholar]
- 14.Hypertension, cholesterol and diabetes medication adherence, health care utilization and expenditure in a Medicare supplemental sample. Campbell Patrick J., Axon David R., Taylor Ann M., Smith Karen, Pickering Matthew, Black Heather, Warholak Terri, Chinthammit Chanadda. Sep 3;2021 Medicine (Baltimore) 100(35):e27143. doi: 10.1097/md.0000000000027143. https://doi.org/10.1097/md.0000000000027143 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 15.Does access to free medication reduce health system costs? An evaluation of the Dispensary of Hope program. Allaire Benjamin T, Tang Yan, Neuwahl Simon, Buell Naomi, Blackburn Hillary, Lankford Mary, Palombo Christopher, Khavjou Olga. Feb;2023 Journal of Managed Care & Specialty Pharmacy. 29(2):187–196. doi: 10.18553/jmcp.2023.29.2.187. https://doi.org/10.18553/jmcp.2023.29.2.187 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 16.Murphy N., Rapfogel N. North Carolina’s expansion of Medicaid should serve as an inspiration to other states. [2023-10-1]. https://www.americanprogress.org/article/north-carolinas-expansion-of-medicaid-should-serve-as-an-inspiration-to-other-states/
- 17.The impact of North Carolina Medicaid expansion on young adults, infant/maternal health, and caregiver well-being. Mims Susan R., Palmer Smith Erica. Sep 1;2023 North Carolina Medical Journal. 84(5) doi: 10.18043/001c.87526. https://doi.org/10.18043/001c.87526 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 18.2022 Annual Report. [2023-10-19]. https://ncafcc.org/wp-content/uploads/2023/10/2022-Annual-Report.pdf Accessed October 19, 2023.
- 19.Delay or avoidance of medical care because of COVID-19–related concerns — United States, June 2020. Czeisler Mark É., Marynak Kristy, Clarke Kristie E.N., Salah Zainab, Shakya Iju, Thierry JoAnn M., Ali Nida, McMillan Hannah, Wiley Joshua F., Weaver Matthew D., Czeisler Charles A., Rajaratnam Shantha M.W., Howard Mark E. Sep 11;2020 MMWR. Morbidity and Mortality Weekly Report. 69(36):1250–1257. doi: 10.15585/mmwr.mm6936a4. https://doi.org/10.15585/mmwr.mm6936a4 [DOI] [PMC free article] [PubMed] [Google Scholar]
- 20.Medication updates. [2023-10-1]. http://medassist.org/medication-list/
- 21.Mobile Free Pharmacy. [2023-10-1]. https://medassist.org/mobile/
