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. 1986 Jan 18;292(6514):163–166. doi: 10.1136/bmj.292.6514.163

Dialysis arthropathy: complication of long term treatment with haemodialysis.

E A Brown, I R Arnold, P E Gower
PMCID: PMC1339036  PMID: 3080116

Abstract

Twenty eight patients who had received haemodialysis for more than 10 years were reviewed to establish the incidence of joint problems. Only six patients had no joint symptoms, one had avascular necrosis, one had had recent septic arthritis, and four had hyperparathyroidism. The remaining 16 patients had no evidence of hyperparathyroidism yet had an arthropathy causing pain and stiffness in many joints, particularly the shoulders. Ten of these 16 patients had a recurrent carpal tunnel syndrome requiring repeated surgical decompressions, which resulted in only partial improvement. Of the eight patients who had received dialysis for more than 15 years, seven had this "dialysis arthropathy" and six had recurrent carpal tunnel syndrome. Dialysis arthropathy is a common and often severe and disabling complication of long term treatment with haemodialysis. The cause is not known, but amyloid was found in a synovial biopsy specimen from one patient.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BYWATERS E. G., DIXON A. S., SCOTT J. T. Joint lesions of hyperparathyroidism. Ann Rheum Dis. 1963 May;22:171–187. doi: 10.1136/ard.22.3.171. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Bailey G. L., Griffiths H. J., Mocelin A. J., Gundy D. H., Hampers C. L., Merrill J. P. Avascular necrosis of the femoral head in patients on chronic hemodialysis. Trans Am Soc Artif Intern Organs. 1972;18(0):401-4, 410. doi: 10.1097/00002480-197201000-00099. [DOI] [PubMed] [Google Scholar]
  3. Brown E. A., Gower P. E. Joint problems in patients on maintenance hemodialysis. Clin Nephrol. 1982 Nov;18(5):247–250. [PubMed] [Google Scholar]
  4. Delmez J. A., Holtmann B., Sicard G. A., Goldberg A. P., Harter H. R. Peripheral nerve entrapment syndromes in chronic hemodialysis patients. Nephron. 1982;30(2):118–123. doi: 10.1159/000182447. [DOI] [PubMed] [Google Scholar]
  5. Dieppe P. A., Crocker P., Huskisson E. C., Willoughby D. A. Apatite deposition disease. A new arthropathy. Lancet. 1976 Feb 7;1(7954):266–269. doi: 10.1016/s0140-6736(76)91400-8. [DOI] [PubMed] [Google Scholar]
  6. Dinarello C. A. Interleukin-1 and the pathogenesis of the acute-phase response. N Engl J Med. 1984 Nov 29;311(22):1413–1418. doi: 10.1056/NEJM198411293112205. [DOI] [PubMed] [Google Scholar]
  7. Elliott R. B., Crossley J. R., Berryman C. C., James A. G. Partial preservation of pancreatic beta-cell function in children with diabetes. Lancet. 1981 Jul 4;2(8236):1–4. doi: 10.1016/s0140-6736(81)90249-x. [DOI] [PubMed] [Google Scholar]
  8. Goldstein S., Winston E., Chung T. J., Chopra S., Pariser K. Chronic arthropathy in long-term hemodialysis. Am J Med. 1985 Jan;78(1):82–86. doi: 10.1016/0002-9343(85)90466-8. [DOI] [PubMed] [Google Scholar]
  9. Hoffman G. S., Schumacher H. R., Paul H., Cherian V., Reed R., Ramsay A. G., Franck W. A. Calcium oxalate microcrystalline-associated arthritis in end-stage renal disease. Ann Intern Med. 1982 Jul;97(1):36–42. doi: 10.7326/0003-4819-97-1-36. [DOI] [PubMed] [Google Scholar]
  10. Jain V. K., Cestero R. V., Baum J. Carpal tunnel syndrome in patients undergoing maintenance hemodialysis. JAMA. 1979 Dec 28;242(26):2868–2869. [PubMed] [Google Scholar]
  11. Llach F., Pederson J. A. Acute joint syndrome (AJS) and maintenance hemodialysis (HD). Proc Clin Dial Transplant Forum. 1979;9:17–22. [PubMed] [Google Scholar]
  12. Massry S. G., Bluestone R., Klinenberg J. R., Coburn J. W. Abnormalities of the musculoskeletal system in hemodialysis patients. Semin Arthritis Rheum. 1975 May;4(4):321–349. doi: 10.1016/0049-0172(75)90016-5. [DOI] [PubMed] [Google Scholar]
  13. Mathews M., Shen F. H., Lindner A., Sherrard D. J. Septic arthritis in hemodialyzed patients. Nephron. 1980;25(2):87–91. doi: 10.1159/000181759. [DOI] [PubMed] [Google Scholar]
  14. Mirahmadi K. S., Coburn J. W., Bluestone R. Calcific periarthritis and hemodialysis. JAMA. 1973 Jan 29;223(5):548–549. [PubMed] [Google Scholar]
  15. Rosenfeld N., Rascoff J. H. Tendon ruptures of the hand associated with renal dialysis. Plast Reconstr Surg. 1980 Jan;65(1):77–79. doi: 10.1097/00006534-198001000-00017. [DOI] [PubMed] [Google Scholar]
  16. Rubin L. A., Fam A. G., Rubenstein J., Campbell J., Saiphoo C. Erosive azotemic osteoarthropathy. Arthritis Rheum. 1984 Oct;27(10):1086–1094. doi: 10.1002/art.1780271002. [DOI] [PubMed] [Google Scholar]
  17. Schwarz A., Keller F., Seyfert S., Pöll W., Molzahn M., Distler A. Carpal tunnel syndrome: a major complication in long-term hemodialysis patients. Clin Nephrol. 1984 Sep;22(3):133–137. [PubMed] [Google Scholar]

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