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. 1986 Feb 15;292(6518):437–441. doi: 10.1136/bmj.292.6518.437

Diminution in energy expenditure during lactation.

P J Illingworth, R T Jung, P W Howie, P Leslie, T E Isles
PMCID: PMC1339421  PMID: 3081114

Abstract

Energy expenditure at rest and in response to a meal and to an infusion of noradrenaline was measured in 12 lactating women and compared with that in seven bottle feeding women and seven non-pregnant, non-lactating controls. The energy response of the lactating women was remeasured after lactation stopped. During lactation the resting metabolic rate was unaltered but there was a reduced response to infusion of noradrenaline and to a meal, which increased to normal control values after lactation stopped. Such reductions in expenditure were not found in women who had been bottle feeding and were tested at a similar six to eight weeks post partum. These findings suggest that metabolic efficiency is enhanced in lactating women, who may not need to increase energy intake to the extent suggested by current recommended dietary allowances.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agius L., Rolls B. J., Rowe E. A., Williamson D. H. Increased lipogenesis in brown adipose tissue of lactating rats fed a cafeteria diet. The possible involvement of insulin in brown adipose tissue hypertrophy. FEBS Lett. 1981 Jan 12;123(1):45–48. doi: 10.1016/0014-5793(81)80016-6. [DOI] [PubMed] [Google Scholar]
  2. Astrup A., Bülow J., Madsen J., Christensen N. J. Contribution of BAT and skeletal muscle to thermogenesis induced by ephedrine in man. Am J Physiol. 1985 May;248(5 Pt 1):E507–E515. doi: 10.1152/ajpendo.1985.248.5.E507. [DOI] [PubMed] [Google Scholar]
  3. Bazelmans J., Nestel P. J., O'Dea K., Esler M. D. Blunted norepinephrine responsiveness to changing energy states in obese subjects. Metabolism. 1985 Feb;34(2):154–160. doi: 10.1016/0026-0495(85)90125-8. [DOI] [PubMed] [Google Scholar]
  4. Berry M. N., Clark D. G., Grivell A. R., Wallace P. G. The contribution of hepatic metabolism to diet-induced thermogenesis. Metabolism. 1985 Feb;34(2):141–147. doi: 10.1016/0026-0495(85)90123-4. [DOI] [PubMed] [Google Scholar]
  5. Butte N. F., Garza C., Stuff J. E., Smith E. O., Nichols B. L. Effect of maternal diet and body composition on lactational performance. Am J Clin Nutr. 1984 Feb;39(2):296–306. doi: 10.1093/ajcn/39.2.296. [DOI] [PubMed] [Google Scholar]
  6. Chromý V., Gergel J., Voznícek J., Krombholzová L., Musil J. Assay of serum free fatty acids by extraction-photometric procedure. Clin Chim Acta. 1977 Oct 15;80(2):327–332. doi: 10.1016/0009-8981(77)90040-7. [DOI] [PubMed] [Google Scholar]
  7. Cunningham S., Leslie P., Hopwood D., Illingworth P., Jung R. T., Nicholls D. G., Peden N., Rafael J., Rial E. The characterization and energetic potential of brown adipose tissue in man. Clin Sci (Lond) 1985 Sep;69(3):343–348. doi: 10.1042/cs0690343. [DOI] [PubMed] [Google Scholar]
  8. Durnin J. V., Womersley J. Body fat assessed from total body density and its estimation from skinfold thickness: measurements on 481 men and women aged from 16 to 72 years. Br J Nutr. 1974 Jul;32(1):77–97. doi: 10.1079/bjn19740060. [DOI] [PubMed] [Google Scholar]
  9. Felig P. Insulin is the mediator of feeding-related thermogenesis: insulin resistance and/or deficiency results in a thermogenic defect which contributes to the pathogenesis of obesity. Clin Physiol. 1984 Aug;4(4):267–273. doi: 10.1111/j.1475-097x.1984.tb00802.x. [DOI] [PubMed] [Google Scholar]
  10. Flint D. J. Role of insulin and the insulin receptor in nutrient partitioning between the mammary gland and adipose tissue. Biochem Soc Trans. 1985 Oct;13(5):828–829. doi: 10.1042/bst0130828. [DOI] [PubMed] [Google Scholar]
  11. Golay A., Schutz Y., Meyer H. U., Thiébaud D., Curchod B., Maeder E., Felber J. P., Jéquier E. Glucose-induced thermogenesis in nondiabetic and diabetic obese subjects. Diabetes. 1982 Nov;31(11):1023–1028. doi: 10.2337/diacare.31.11.1023. [DOI] [PubMed] [Google Scholar]
  12. Howie P. W., McNeilly A. S., McArdle T., Smart L., Houston M. The relationship between suckling-induced prolactin response and lactogenesis. J Clin Endocrinol Metab. 1980 Apr;50(4):670–673. doi: 10.1210/jcem-50-4-670. [DOI] [PubMed] [Google Scholar]
  13. Jung R. T., Shetty P. S., James W. P., Barrand M. A., Callingham B. A. Reduced thermogenesis in obesity. Nature. 1979 May 24;279(5711):322–323. doi: 10.1038/279322a0. [DOI] [PubMed] [Google Scholar]
  14. Prentice A. M., Whitehead R. G., Roberts S. B., Paul A. A. Long-term energy balance in child-bearing Gambian women. Am J Clin Nutr. 1981 Dec;34(12):2790–2799. doi: 10.1093/ajcn/34.12.2790. [DOI] [PubMed] [Google Scholar]
  15. Schutz Y., Lechtig A., Bradfield R. B. Energy expenditures and food intakes of lactating women in Guatemala. Am J Clin Nutr. 1980 Apr;33(4):892–902. doi: 10.1093/ajcn/33.4.892. [DOI] [PubMed] [Google Scholar]
  16. Shetty P. S., Jung R. T., James W. P., Barrand M. A., Callingham B. A. Postprandial thermogenesis in obesity. Clin Sci (Lond) 1981 May;60(5):519–525. doi: 10.1042/cs0600519. [DOI] [PubMed] [Google Scholar]
  17. Trayhurn P. Decreased capacity for non-shivering thermogenesis during lactation in mice. Pflugers Arch. 1983 Aug;398(3):264–265. doi: 10.1007/BF00657164. [DOI] [PubMed] [Google Scholar]
  18. Trayhurn P., Douglas J. B., McGuckin M. M. Brown adipose tissue thermogenesis is 'suppressed' during lactation in mice. Nature. 1982 Jul 1;298(5869):59–60. doi: 10.1038/298059a0. [DOI] [PubMed] [Google Scholar]
  19. Trinder P. Determination of blood glucose using an oxidase-peroxidase system with a non-carcinogenic chromogen. J Clin Pathol. 1969 Mar;22(2):158–161. doi: 10.1136/jcp.22.2.158. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Whitehead R. G., Paul A. A., Cole T. J. How much breast milk do babies need? Acta Paediatr Scand Suppl. 1982;299:43–50. doi: 10.1111/j.1651-2227.1982.tb09626.x. [DOI] [PubMed] [Google Scholar]

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