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Journal of Accident & Emergency Medicine logoLink to Journal of Accident & Emergency Medicine
. 1996 Nov;13(6):422–424. doi: 10.1136/emj.13.6.422

Hydrochloric acid inhalation: who needs admission?

S H Boyce 1, K A Simpson 1
PMCID: PMC1342817  PMID: 8947805

Abstract

Nine pharmaceutical workers were exposed to hydrochloric acid (HCl) fumes. Four were discharged with no symptoms after a 4 h observation period in the accident and emergency (A&E) department. The remaining five were admitted to the medical unit because of severe symptoms, reduced peak expiratory flow rate (PEFR), or hypoxaemia. Treatment was symptomatic and discharge followed 24 h later. Only one patient, discharged from the medical unit, developed long term airway hyper-reactivity, superimposed on a background of chronic obstructive airways disease. Thus patients who are minimally symptomatic with normal PEFR and oxygen saturation values can be safely discharged from the A&E department after a short observation period of 4 h with advice to return if dyspnoea occurs. Caution should be employed in severely symptomatic patients, those with pre-existing lung pathology or reduced PEFR, and hypoxaemic patients, where observation for at least 24 h is recommended.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boulet L. P. Increases in airway responsiveness following acute exposure to respiratory irritants. Reactive airway dysfunction syndrome or occupational asthma? Chest. 1988 Sep;94(3):476–481. doi: 10.1378/chest.94.3.476. [DOI] [PubMed] [Google Scholar]
  2. Burleigh-Flayer H., Wong K. L., Alarie Y. Evaluation of the pulmonary effects of HCl using CO2 challenges in guinea pigs. Fundam Appl Toxicol. 1985 Oct;5(5):978–985. [PubMed] [Google Scholar]
  3. Deschamps D., Soler P., Rosenberg N., Baud F., Gervais P. Persistent asthma after inhalation of a mixture of sodium hypochlorite and hydrochloric acid. Chest. 1994 Jun;105(6):1895–1896. doi: 10.1378/chest.105.6.1895. [DOI] [PubMed] [Google Scholar]
  4. Fine J. M., Gordon T., Thompson J. E., Sheppard D. The role of titratable acidity in acid aerosol-induced bronchoconstriction. Am Rev Respir Dis. 1987 Apr;135(4):826–830. doi: 10.1164/arrd.1987.135.4.826. [DOI] [PubMed] [Google Scholar]
  5. Finnegan M. J., Hodson M. E. Prolonged hypoxaemia following inhalation of hydrogen chloride vapour. Thorax. 1989 Mar;44(3):238–239. doi: 10.1136/thx.44.3.238. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Kaplan H. L., Anzueto A., Switzer W. G., Hinderer R. K. Effects of hydrogen chloride on respiratory response and pulmonary function of the baboon. J Toxicol Environ Health. 1988;23(4):473–493. doi: 10.1080/15287398809531129. [DOI] [PubMed] [Google Scholar]
  7. Rosenthal T., Baum G. L., Frand U., Molho M. Poisoning caused by inhalation of hydrogen chloride, phosphorus oxychloride, phosphorus pentachloride, oxalyl chloride, and oxalic acid. Chest. 1978 May;73(5):623–626. doi: 10.1378/chest.73.5.623. [DOI] [PubMed] [Google Scholar]
  8. Stavert D. M., Archuleta D. C., Behr M. J., Lehnert B. E. Relative acute toxicities of hydrogen fluoride, hydrogen chloride, and hydrogen bromide in nose- and pseudo-mouth-breathing rats. Fundam Appl Toxicol. 1991 May;16(4):636–655. doi: 10.1016/0272-0590(91)90152-t. [DOI] [PubMed] [Google Scholar]
  9. Stevens B., Koenig J. Q., Rebolledo V., Hanley Q. S., Covert D. S. Respiratory effects from the inhalation of hydrogen chloride in young adult asthmatics. J Occup Med. 1992 Sep;34(9):923–929. [PubMed] [Google Scholar]

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