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. 1974 Jul;180(1):130–135. doi: 10.1097/00000658-197407000-00020

Hypoglycemia and Insular Hyperplasia: Review of 148 cases

Paride Stefanini, Manlio Carboni, Neri Patrassi, Antonio Basoli
PMCID: PMC1343621  PMID: 4365152

Abstract

On the bases of personal experience and the series of 148 cases from an international inquiry and a review of the literature, the relation between insular hyperplasia and hypoglycemia was examined. The fundamental points in this investigation included: age, diagnostic investigations, histological findings and postoperative results. The data on the patients with insular hyperplasia indicates that 83% were of adult age. Insular hyperplasia was the only abnormal factor determined to be present. Through treatment a high percentage of cases (71%) was cured. From a practical surgical point of view, differentiation between occult insulomas and insular hyperplasia is not critical. Consequently, good results can be achieved in botlh diseases by practicing a progressive blind resection guided by examination of the operated specimen and by intra-operative blood sugar levels.

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Selected References

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