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. 1976 Apr;183(4):358–364. doi: 10.1097/00000658-197604000-00005

In vitro penetration of topical antiseptics through eschar of burn patients.

M M Stefanides Sr, C E Copeland, S D Kominos, R B Yee
PMCID: PMC1344204  PMID: 1267492

Abstract

The ability of topical antiseptics to penetrate eschar of burn patients was determined by the agar diffusion technique. Gentamicin sulfate, mafenide acetate, nitrofurazone, povidone-iodine, silver nitrate, and silver sulfadiazine were tested against clinical isolates of Candida albicans, Staphylococcus, Streptococcus, and gram-negative bacilli including Pseudomonas aeruginosa. In practically all instances, the diameters of the zones of inhibition observed using eschar were comparable to those obtained with filter-paper discs. This finding showed that the antimicrobial agents could penetrate eschar and retain their effectiveness after penetration.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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