Abstract
A benign hepatic adenoma in a young woman taking oral contraceptives for 7 years is reported. The diagnosis must be suspected in any young woman taking oral contraceptive agents who develop signs and symptoms of acute cholecystitis with hepatomegaly or mass, or when signs and symptoms of non-traumatic intraabdominal hemorrhage are present. Rupture of the tumor is a life-threatening complication. Treatment should be either hepatic lobectomy or wide local resection.
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- Antoniades K., Brooks C. E., Jr Hemoperitoneum from liver cell adenoma in a patient on oral contraceptives. Surgery. 1975 Jan;77(1):137–139. [PubMed] [Google Scholar]
- Baum J. K., Bookstein J. J., Holtz F., Klein E. W. Possible association between benign hepatomas and oral contraceptives. Lancet. 1973 Oct 27;2(7835):926–929. doi: 10.1016/s0140-6736(73)92594-4. [DOI] [PubMed] [Google Scholar]
- Berg J. W., Ketalaar R. J., Rose E. F., Vernon R. G. Letter: Hepatomas and oral contraceptives. Lancet. 1974 Aug 10;2(7876):349–350. doi: 10.1016/s0140-6736(74)91725-5. [DOI] [PubMed] [Google Scholar]
- Cattan D., Vesin P., Wautier J., Kalifat R., Meignan S. Letter: Liver tumours and steroid hormones. Lancet. 1974 May 4;1(7862):878–878. doi: 10.1016/s0140-6736(74)90542-x. [DOI] [PubMed] [Google Scholar]
- Contostavlos D. L. Letter: Benign hepatomas and oral contraceptives. Lancet. 1973 Nov 24;2(7839):1200–1200. doi: 10.1016/s0140-6736(73)92956-5. [DOI] [PubMed] [Google Scholar]
- Henderson J. T., Richmond J., Sumerling M. D. Androgenic-anabolic steroid therapy and hepatocellular carcinoma. Lancet. 1973 Apr 28;1(7809):934–934. doi: 10.1016/s0140-6736(73)91384-6. [DOI] [PubMed] [Google Scholar]
- Horvath E., Kovacs K., Ross R. C. Letter: Benign hepatoma in a young woman on contraceptive steroids. Lancet. 1974 Mar 2;1(7853):357–358. doi: 10.1016/s0140-6736(74)93111-0. [DOI] [PubMed] [Google Scholar]
- Johnson F. L., Lerner K. G., Siegel M., Feagler J. R., Majerus P. W., Hartmann J. R., Thomas E. D. Association of androgenic-anabolic steroid therapy with development of hepatocellular carcinoma. Lancet. 1972 Dec 16;2(7790):1273–1276. doi: 10.1016/s0140-6736(72)92649-9. [DOI] [PubMed] [Google Scholar]
- Knapp W. A., Ruebner B. H. Letter: Hepatomas and oral contraceptives. Lancet. 1974 Feb 16;1(7851):270–271. doi: 10.1016/s0140-6736(74)92580-x. [DOI] [PubMed] [Google Scholar]
- Lingeman C. H. Letter: Liver-cell neoplasms and oral contraceptives. Lancet. 1974 Jan 12;1(7846):64–64. doi: 10.1016/s0140-6736(74)93063-3. [DOI] [PubMed] [Google Scholar]
- O'Sullivan J. P., Wilding R. P. Liver hamartomas in patients on oral contraceptives. Br Med J. 1974 Jul 6;3(5922):7–10. doi: 10.1136/bmj.3.5922.7. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ziegenfuss J., Carabasi R. Androgens and hepatocellular carcinoma. Lancet. 1973 Feb 3;1(7797):262–262. doi: 10.1016/s0140-6736(73)90098-6. [DOI] [PubMed] [Google Scholar]