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Annals of Surgery logoLink to Annals of Surgery
. 1980 Apr;191(4):391–396. doi: 10.1097/00000658-198004000-00001

The role of H.I.D.A./P.I.P.I.D.A. scanning in diagnosing cystic duct obstruction.

C A Suarez, F Block, D Bernstein, A Serafini, G Rodman Jr, R Zeppa
PMCID: PMC1344557  PMID: 7369804

Abstract

A newer approach to the early diagnosis of acute biliary tract disease is review. Ninety-two patients were evaluated with a new hepatobiliary agent (H.I.D.A/P.I.P.D.A.) for the presence of cystic duct obstruction. Seven patients with suspected acute gall bladder disease were dropped from the study for the lack of pathologic confirmation of the diagnosis. Forty-four of the remaining 85 patients were subsequently operated on and found to have acute cholecystitis. Forty-three of the 44 had cystic duct obstruction demonstrated on H.I.D.A. Scan (one false negative). An additional 23 patients underwent cholecystectomy for chronic disease. In this group, the gallbladder scan was only 43% (10/23) accurate in correctly identifying disease. Eighteen patients with nonbiliary disease had normal scans. The accuracy of ultrasonography and the scan are also compared in a smaller subgroup of 53 patients who had both studies.

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Selected References

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  1. Bornhurst R. A., Heitzman E. R., McAfee J. G. Double-dose drip-infusion cholangiography. An analysis of 107 consecutive cases. JAMA. 1968 Nov 11;206(7):1489–1494. [PubMed] [Google Scholar]
  2. Cheung L. Y., Chang F. C. Intravenous cholangiography in the diagnosis of acute cholecystitis. Arch Surg. 1978 May;113(5):568–570. doi: 10.1001/archsurg.1978.01370170030004. [DOI] [PubMed] [Google Scholar]
  3. Dempsey P. J., Phillips J. F., Warren D. L., Donovan A. J. Cholecystosonography for the diagnosis of cholecystolithiasis. Ann Surg. 1978 May;187(5):465–474. doi: 10.1097/00000658-197805000-00003. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Doust B. D. The use of ultrasound in the diagnosis of gastroenterological disease. Gastroenterology. 1976 Apr;70(4):602–610. [PubMed] [Google Scholar]
  5. FISCHER H. W. THE EXCRETION OF IODIPAMIDE: RELATION OF BILE AND URINE OUTPUTS TO DOSE. Radiology. 1965 Mar;84:483–491. doi: 10.1148/84.3.483. [DOI] [PubMed] [Google Scholar]
  6. Gardner B., Masur R., Fujimoto J. Factors influencing the timing of cholecystectomy in acute cholecystitis. Am J Surg. 1973 Jun;125(6):730–733. doi: 10.1016/0002-9610(73)90174-8. [DOI] [PubMed] [Google Scholar]
  7. Glenn F. Acute cholecystitis. Surg Gynecol Obstet. 1976 Jul;143(1):56–60. [PubMed] [Google Scholar]
  8. Glenn F., Grafe W. R., Jr Historical events in biliary tract surgery. Arch Surg. 1966 Nov;93(5):848–852. doi: 10.1001/archsurg.1966.01330050152025. [DOI] [PubMed] [Google Scholar]
  9. HINCHEY E. J., ELIAS G. L., HAMPSON L. G. ACUTE CHOLECYSTITIS. Surg Gynecol Obstet. 1965 Mar;120:475–480. [PubMed] [Google Scholar]
  10. Hood J. B., Seymour E. Q. Accuracy of oral cholecystography in cholelithiasis. Am Surg. 1978 Jul;44(7):435–436. [PubMed] [Google Scholar]
  11. McAvoy J. M., Roth J., Rees W. V., Orr F., Dainko E. A. Role of ultrasonography in the primary diagnosis of cholelithiasis: an analysis of fifty cases. Am J Surg. 1978 Sep;136(3):309–312. doi: 10.1016/0002-9610(78)90282-9. [DOI] [PubMed] [Google Scholar]
  12. Morrow D. J., Thompson J., Wilson S. E. Acute cholecystitis in the elderly: a surgical emergency. Arch Surg. 1978 Oct;113(10):1149–1152. doi: 10.1001/archsurg.1978.01370220035006. [DOI] [PubMed] [Google Scholar]
  13. Paré P., Shaffer E. A., Rosenthall L. Nonvisualization of the gallbladder by 99mTc-HIDA cholescintigraphy as evidence of cholecystitis. Can Med Assoc J. 1978 Feb 18;118(4):384–386. [PMC free article] [PubMed] [Google Scholar]
  14. Prian G. W., Norton L. W., Eule J., Jr, Eiseman B. Clinical indications and accuracy of gray scale ultrasonography in the patient with suspected biliary tract disease. Am J Surg. 1977 Dec;134(6):705–711. doi: 10.1016/0002-9610(77)90307-5. [DOI] [PubMed] [Google Scholar]
  15. Roller R. J., Mallory A., Caruthers S. B., Schaefer J. W. Oral cholecystography after alcoholic pancreatitis. Gastroenterology. 1977 Aug;73(2):218–220. [PubMed] [Google Scholar]
  16. Rosenthall L. Clinical experience with the newer hepatobiliary radiopharmaceuticals. Can J Surg. 1978 Jul;21(4):297–300. [PubMed] [Google Scholar]
  17. Taavitsainen M., Järvinen H., Tallroth K. Cholescintigraphy in the diagnosis of acute cholecystitis. Ann Clin Res. 1978 Aug;10(4):227–234. [PubMed] [Google Scholar]
  18. Tabrisky J., Lindstrom R. R., Herman M. W., Castagna J., Sarti D. Value of gallbladder B-scan ultrasonography. Gastroenterology. 1975 May;68(5 Pt 1):1246–1252. [PubMed] [Google Scholar]
  19. Thal E. R., Weigelt J., Landay M., Conrad M. Evaluation of ultrasound in the diagnosis of acute and chronic biliary tract disease. Arch Surg. 1978 Apr;113(4):500–503. doi: 10.1001/archsurg.1978.01370160158027. [DOI] [PubMed] [Google Scholar]
  20. Thorpe C. D., Olsen W. R., Fischer H., Doust V. L., Joseph R. R. Emergency intravenous cholangiography in patients with acute abdominal pain. Am J Surg. 1973 Jan;125(1):46–50. doi: 10.1016/0002-9610(73)90007-x. [DOI] [PubMed] [Google Scholar]
  21. Tjen H. S., van der Pompe W. B., Cox P. H. Technetium-99m-labelled diethyl-acetanilido-iminodiacetate: a new hepatobiliary agent. A preliminary report. Br J Radiol. 1977 Oct;50(598):735–739. doi: 10.1259/0007-1285-50-598-735. [DOI] [PubMed] [Google Scholar]
  22. Verdegaal W. P. Hepatobiliary scanning. Neth J Med. 1978;21(4):176–182. [PubMed] [Google Scholar]
  23. Wistow B. W., Gagne G. M., Henderson R. W., McAfee J. G., Hall R. C., Grossman Z. D. Experimental and clinical trials of new 99mTc-labeled hepatobiliary agents. Radiology. 1978 Sep;128(3):793–794. doi: 10.1148/128.3.793. [DOI] [PubMed] [Google Scholar]
  24. Zusmer N. R., Harwood S. R., Pevsner N. H., Janowitz W. R., Serafini A. N. Gray scale ultrasonography and rose bengal scintigraphy in the evaluation of the patient with jaundice. Surg Gynecol Obstet. 1978 Sep;147(3):321–327. [PubMed] [Google Scholar]
  25. van der Linden W., Sunzel H. Early versus delayed operation for acute cholecystitis. A controlled clinical trial. Am J Surg. 1970 Jul;120(1):7–13. doi: 10.1016/s0002-9610(70)80133-7. [DOI] [PubMed] [Google Scholar]

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