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. 1980 Apr;191(4):488–493. doi: 10.1097/00000658-198004000-00016

Analysis of staging and management of patients with sarcoma: a ten-year experience.

H F Sears, R Hopson, W Inouye, T Rizzo, P J Grotzinger
PMCID: PMC1344572  PMID: 7369814

Abstract

Over ten years, 70 patients with soft tissue sarcoma were treated for their primary tumors at the hospital of The Fox Chase Cancer Center. The clinical characteristics of these tumors are correlated with the outcome of various management efforts. The results of these evaluations identify three groups that can provide the basis for future treatment decisions and stratification for randomized studies of management options. The first group of patients, those with small well differentiated tumors, have no systemic spread regardless of the treatment modality used. The second group, those with large (greater than 5 cm) tumors that are moderately or poorly differentiated, do uniformly poorly despite the management techniques used. An intermediate group, those with high grade or large size but not both, have outcomes which may be correlated to treatment modalities.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BOWDEN L., BOOHER R. J. The principles and technique of resection of soft parts for sarcoma. Surgery. 1958 Dec;44(6):963–977. [PubMed] [Google Scholar]
  2. Brennhovd I. O. The treatment of soft tissue sarcomas--a plea for a more urgent and aggressive approach. Acta Chir Scand. 1966 May;131(5):438–442. [PubMed] [Google Scholar]
  3. Cantin J., McNeer G. P., Chu F. C., Booher R. J. The problem of local recurrence after treatment of soft tissue sarcoma. Ann Surg. 1968 Jul;168(1):47–53. doi: 10.1097/00000658-196807000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Castro E. B., Hajdu S. I., Fortner J. G. Surgical therapy of fibrosarcoma of extremities: a reappraisal. Arch Surg. 1973 Aug;107(2):284–286. doi: 10.1001/archsurg.1973.01350200146030. [DOI] [PubMed] [Google Scholar]
  5. Ferrell H. W., Frable W. J. Soft part sarcomas revisited. Review and comparison of a second series. Cancer. 1972 Aug;30(2):475–480. doi: 10.1002/1097-0142(197208)30:2<475::aid-cncr2820300227>3.0.co;2-p. [DOI] [PubMed] [Google Scholar]
  6. Gerner R. E., Moore G. E., Pickren J. W. Soft tissue sarcomas. Ann Surg. 1975 Jun;181(6):803–808. doi: 10.1097/00000658-197506000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Gilbert H. A., Kagan A. R., Winkley J. Management of soft tissue sarcomas of the extremities. Surg Gynecol Obstet. 1974 Dec;139(6):914–918. [PubMed] [Google Scholar]
  8. Goepfert H., Lindberg R. D., Sinkovics J. G., Ayala A. G. Soft-tissue sarcoma of the head and neck after puberty. Arch Otolaryngol. 1977 Jun;103(6):365–368. doi: 10.1001/archotol.1977.00780230087015. [DOI] [PubMed] [Google Scholar]
  9. HARE H. F., CERNY M. J., Jr SOFT TISSUE SARCOMA. A REVIEW OF 200 CASES. Cancer. 1963 Oct;16:1332–1337. doi: 10.1002/1097-0142(196310)16:10<1332::aid-cncr2820161014>3.0.co;2-z. [DOI] [PubMed] [Google Scholar]
  10. Krementz E. T., Carter R. D., Sutherland C. M., Hutton I. Chemotherapy of sarcomas of the limbs by regional perfusion. Ann Surg. 1977 May;185(5):555–564. doi: 10.1097/00000658-197705000-00008. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Lindberg R. D. Soft tissue sarcomas. Curr Probl Cancer. 1976 Nov;1(5):4–13. doi: 10.1016/s0147-0272(76)80002-5. [DOI] [PubMed] [Google Scholar]
  12. McNeer G. P., Cantin J., Chu F., Nickson J. J. Effectiveness of radiation therapy in the management of sarcoma of the soft somatic tissues. Cancer. 1968 Aug;22(2):391–397. doi: 10.1002/1097-0142(196808)22:2<391::aid-cncr2820220217>3.0.co;2-q. [DOI] [PubMed] [Google Scholar]
  13. Rosenberg S. A., Kent H., Costa J., Webber B. L., Young R., Chabner B., Baker A. R., Brennan M. F., Chretien P. B., Cohen M. H. Prospective randomized evaluation of the role of limb-sparing surgery, radiation therapy, and adjuvant chemoimmunotherapy in the treatment of adult soft-tissue sarcomas. Surgery. 1978 Jul;84(1):62–69. [PubMed] [Google Scholar]
  14. Russell W. O., Cohen J., Enzinger F., Hajdu S. I., Heise H., Martin R. G., Meissner W., Miller W. T., Schmitz R. L., Suit H. D. A clinical and pathological staging system for soft tissue sarcomas. Cancer. 1977 Oct;40(4):1562–1570. doi: 10.1002/1097-0142(197710)40:4<1562::aid-cncr2820400428>3.0.co;2-6. [DOI] [PubMed] [Google Scholar]
  15. STOUT A. P. Pseudosarcomatous fascitis in children. Cancer. 1961 Nov-Dec;14:1216–1222. doi: 10.1002/1097-0142(196111/12)14:6<1216::aid-cncr2820140611>3.0.co;2-w. [DOI] [PubMed] [Google Scholar]
  16. Scanlon P. W. Split-dose radiotherapy for radioresistant bone and soft tissue sarcoma: ten years' experience. Am J Roentgenol Radium Ther Nucl Med. 1972 Mar;114(3):544–552. doi: 10.2214/ajr.114.3.544. [DOI] [PubMed] [Google Scholar]
  17. Shiu M. H., Castro E. B., Hajdu S. I., Fortner J. G. Surgical treatment of 297 soft tissue sarcomas of the lower extremity. Ann Surg. 1975 Nov;182(5):597–602. doi: 10.1097/00000658-197511000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Suit H. D., Russell W. O., Martin R. G. Management of patients with sarcoma of soft tissue in an extremity. Cancer. 1973 May;31(5):1247–1255. doi: 10.1002/1097-0142(197305)31:5<1247::aid-cncr2820310533>3.0.co;2-a. [DOI] [PubMed] [Google Scholar]
  19. Suit H. D., Russell W. O., Martin R. G. Sarcoma of soft tissue: clinical and histopathologic parameters and response to treatment. Cancer. 1975 May;35(5):1478–1483. doi: 10.1002/1097-0142(197505)35:5<1478::aid-cncr2820350537>3.0.co;2-1. [DOI] [PubMed] [Google Scholar]
  20. Townsend C. M., Jr, Eilber F. R., Morton D. L. Skeletal and soft tissue sarcomas. Treatment with adjuvant immunotherapy. JAMA. 1976 Nov 8;236(19):2187–2189. [PubMed] [Google Scholar]
  21. VAN DER WERF-MESSING B., VAN UNNIK J. FIBROSARCOMA OF THE SOFT TISSUES: A CLINICOPATHOLOGIC STUDY. Cancer. 1965 Sep;18:1113–1123. doi: 10.1002/1097-0142(196509)18:9<1113::aid-cncr2820180911>3.0.co;2-k. [DOI] [PubMed] [Google Scholar]

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