Skip to main content
NCBI home page
Annals of Surgery logoLink to Annals of Surgery
. 1980 Jan;191(1):19–22. doi: 10.1097/00000658-198001000-00004

Gallbladder carcinoma first diagnosed at microscopic examination of gallbladders removed for presumed benign disease.

L Bergdahl
PMCID: PMC1344611  PMID: 7352774

Abstract

The patients who survive gallbladder carcinomas more than five years are usually those in whom the carcinoma was first diagnosed at microscopic examination of gallbladders removed for presumed benign disease. A group of 32 such patients (from a series of 120 cases) was studied. The prognosis was very bad (longest survival 2.5 years) in 21 of the patients where the cancer involved all the layers of the gallbladder wall. The prognosis was far better in the 11 patients in which the cancer was confined to the mucosa or submucosa. Sixty-four per cent of the patients were alive after 5 years and 44% after 10 years. Five of the 11 patients died because of recurrence. Simple cholecystectomy had been performed in all the patients except one who underwent a right hepatic lobectomy. Radical cholecystectomy including a wedge resection of liver tissue and dissection of the regional lymph nodes is recommended in all patients with inapparent gallbladder carcinomas.

Full text

PDF
19

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adson M. A. Carcinoma of the gallbladder. Surg Clin North Am. 1973 Oct;53(5):1203–1216. doi: 10.1016/s0039-6109(16)40147-7. [DOI] [PubMed] [Google Scholar]
  2. Andersson A., Bergdahl L., Zeuchner E. Karzinom der Gallenblase als unerwartete histologische Diagnose bei Chole,ystitis und Gallensteinleiden. Zentralbl Chir. 1976;101(21):1314–1317. [PubMed] [Google Scholar]
  3. BOSSART P. A., PATTERSON A. H., ZINTEL H. A. Carcinoma of the gallbladder. A report of seventy-six cases. Am J Surg. 1962 Mar;103:366–369. doi: 10.1016/0002-9610(62)90227-1. [DOI] [PubMed] [Google Scholar]
  4. BURDETTE W. J. Carcinoma of the gall bladder. Ann Surg. 1957 Jun;145(6):832-44; discussion, 844-7. doi: 10.1097/00000658-195706000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bivins B. A., Meeker W. R., Griffen W. O., Jr Importance of histologic classification of carcinoma of the gallbladder. Am Surg. 1975 Mar;41(3):121–124. [PubMed] [Google Scholar]
  6. Brasfield R. D. Right Hepatic Lobectomy for Carcinoma of the Gallbladder: A Five-Year Cure. Ann Surg. 1961 Apr;153(4):563–566. doi: 10.1097/00000658-196104000-00020. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. FAHIM R. B., McDONALD J. R., RICHARDS J. C., FERRIS D. O. Carcinoma of the gallbladder: a study of its modes of spread. Ann Surg. 1962 Jul;156:114–124. doi: 10.1097/00000658-196207000-00021. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Frank S. A., Spjut H. J. Inapparent carcinoma of the gallbladder. Am Surg. 1967 May;33(5):367–372. [PubMed] [Google Scholar]
  9. GLENN F., HAYS D. M. The scope of radical surgery in the treatment of malignant tumors of the extrahepatic biliary tract. Surg Gynecol Obstet. 1954 Nov;99(5):529–541. [PubMed] [Google Scholar]
  10. Keill R. H., DeWeese M. S. Primary carcinoma of the gallbladder. Am J Surg. 1973 Jun;125(6):726–729. doi: 10.1016/0002-9610(73)90173-6. [DOI] [PubMed] [Google Scholar]
  11. Klein J. B., Finck F. M. Primary carcinoma of the gallbladder. Review of 28 cases. Arch Surg. 1972 Jun;104(6):769–772. doi: 10.1001/archsurg.1972.04180060019004. [DOI] [PubMed] [Google Scholar]
  12. Litwin M. S. Primary carcinoma of the gallbladder. A review of 78 patients. Arch Surg. 1967 Aug;95(2):236–240. doi: 10.1001/archsurg.1967.01330140074017. [DOI] [PubMed] [Google Scholar]
  13. Pemberton L. B., Diffenbaugh W. F., Strohl E. L. The surgical significance of carcinoma of the gallbladder. Am J Surg. 1971 Sep;122(3):381–383. doi: 10.1016/0002-9610(71)90263-7. [DOI] [PubMed] [Google Scholar]
  14. Piehler J. M., Crichlow R. W. Primary carcinoma of the gallbladder. Arch Surg. 1977 Jan;112(1):26–30. doi: 10.1001/archsurg.1977.01370010028005. [DOI] [PubMed] [Google Scholar]
  15. Piehler J. M., Crichlow R. W. Primary carcinoma of the gallbladder. Surg Gynecol Obstet. 1978 Dec;147(6):929–942. [PubMed] [Google Scholar]
  16. RIVKIN L. M. Carcinoma of gall bladder; report of fifty-two operative cases and résumé of the literature. AMA Arch Surg. 1955 Jan;70(1):128–135. [PubMed] [Google Scholar]
  17. TRAGERMAN L. J. Primary carcinoma of the gallbladder; review of 173 cases. Calif Med. 1953 May;78(5):431–437. [PMC free article] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES